LOCUS       NZ_CM002285            43697 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2438349
            Orig. end                         :: 2482046
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..43697
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /candidate_cluster_numbers="4"
                     /contig_edge="False"
                     /product="HR-T2PKS"
                     /product="terpene-precursor"
                     /product="butyrolactone"
                     /region_number="18"
                     /rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..43697
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /detection_rules="AfsA"
                     /kind="neighbouring"
                     /product="HR-T2PKS"
                     /product="terpene-precursor"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /protoclusters="3"
                     /tool="antismash"
     cand_cluster    1..41766
                     /SMILES=""
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /kind="single"
                     /product="HR-T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41766
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[<20000:21766](-)"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<20001..21766)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
     cand_cluster    47..21120
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    47..21120
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10046:11120](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(10047..11120)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
     gene            811..>1292
                     /locus_tag="M878_RS94050"
                     /old_locus_tag="M878_11275"
     CDS             811..>1292
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016469738.1"
                     /locus_tag="M878_RS94050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11275"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_078630602.1"
                     /transl_table=11
                     /translation="MKLSQGVEWALHCTVALAQSRAQAPVSRRTLAGYFDLPEAYLAKH
                     LKSLVQAGVLTATSGPRGGFRLARPASGITALDIVEAIEGTLPPFVCTEIRQRGECAVP
                     PEKCTGPCPVAKVMYDADRAWRDHLRSVTVAGLVDRLPPWSHSHAGTPTEADASTVL"
     assembly_gap    1293..1317
                     /estimated_length=25
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     gene            complement(<1318..2378)
                     /locus_tag="M878_RS60475"
                     /old_locus_tag="M878_11280"
     CDS             complement(<1318..2378)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019524511.1"
                     /locus_tag="M878_RS60475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11280"
                     /product="2-oxoacid:ferredoxin oxidoreductase subunit beta"
                     /protein_id="WP_023546231.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.2e-30, bitscore:
                     103.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTAGGLLQLVPKAEAKQSMKDFKSDQEVRWCPGCGDYAILAAV
                     QGFMPELGLARENIVFVSGIGCSSRFPYYMNTYGMHSIHGRAPAIATGLATSRRDLSVW
                     VVTGDGDALSIGGNHLIHALRRNVNLKILLFNNRIYGLTKGQYSPTSELGKITKSTPMG
                     SLDAPFNPVSLAIGAEASFVARTIDSDRKHLTEVLRQAADHPGTALIEIYQNCNIFNDG
                     AFDALKDTQQAQEALIRLEHGQPIRFGTDGARGVVRNRATGDLEAVTVTADNEADILVH
                     DAHATSPTTAFALSRLADPDTLHQTPIGVFRSVERPVYDTAMADQLDTAIEQKGKGDLA
                     ALLAGGDTWTVIG"
     gene            complement(2371..>4221)
                     /locus_tag="M878_RS60480"
                     /old_locus_tag="M878_11285"
     CDS             complement(2371..>4221)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004984609.1"
                     /locus_tag="M878_RS60480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11285"
                     /product="2-oxoacid:acceptor oxidoreductase subunit alpha"
                     /protein_id="WP_023546232.1"
                     /transl_table=11
                     /translation="KDVRRLDRVIIRFAGDSGDGMQLTGDRFTSETASFGNDLSTLPNF
                     PAEIRAPAGTLPGVSSFQLHFADHDILTPGDAPNVLVAMNPAALKANVGDLPRGAEIIV
                     NTDEFTKRALQKVGYAASPLQDGSLDGYSLHPVPLTTLTVQALKEFDLSRKEAERSKNM
                     FALGLLSWMYHRPTEGTERFLRSKFAKKPEIMAANIAAFRAGWNFGETTEDFAVSFEVA
                     PAAKAFPVGTYRNISGNLALAYGLITASRQADLPLFLGSYPITPASDILHELSRHKNFG
                     VRTFQAEDEIAGIGAALGAAFGGSLAVTTTSGPGVALKSETIGLAVSLELPLLVVDIQR
                     GGPSTGLPTKTEQADLLQAMFGRNGEAPVPIVAPRTPADCFGAALEAARIALAYRTPVM
                     LLSDGYLANGSEPWRIPDLDELPDLRVQFATSANHTLADGSEVFWPYKRDPRTLARPWA
                     IPGTPGLEHRIGGIEKQDGTGNISYDPANHDFMVRTRQAKIDGIEVADLEVDDPDGART
                     LVLGWGSTYGPITAAVRRLRRAGEPIAQAHLRHLNPFPRNLGEVLRGYDKVVIPEMNLG
                     QLATLIRAKYLVDAHSYNQVNGMPFKAEQLARALKEAIDD"
     assembly_gap    4222..4246
                     /estimated_length=25
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     gene            4594..6813
                     /locus_tag="M878_RS60485"
                     /old_locus_tag="M878_11290"
     CDS             4594..6813
                     /EC_number="4.1.3.27"
                     /GO_function="GO:0004049 - anthranilate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF010081.0"
                     /locus_tag="M878_RS60485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11290"
                     /product="anthranilate synthase component I"
                     /protein_id="WP_023546233.1"
                     /transl_table=11
                     /translation="MSSLDITGVPTAAPVDLRWSTASGVEVRLTACHAGSAQAVRARLE
                     TALDERRGMLLFRGHDRVLGYVDPPLELSVESTELTVRALNDRGRVLIPALRTVLAGHL
                     LLEPGTNDTLRGRARPTSGVFAEEDRTRNAGVFGAVRAVLRGLSASEDSLLGLYGAFGY
                     DLIFQVDPVERHQERRTGDRDLVLHLPDEIWELDLRQDLAVRHRYDFTFAGADTGGLPR
                     TSPVQPFVPGAPLAARDHAPGEYAQVVAKAMPLFRSGDLFEVVPSQVFRRPCPTPPSDV
                     FRRLRLRNPAPHSLLMNLGEREYLVGASPEMFVRVRHEPGAEGNRSVIESSPISGTIAR
                     GQDALEDARRIRELLGSVKEESELTMCTDVDRNDKARVCEPGSVEVVDRRRIEMYSALI
                     HTVDRVRGVLRRDRDALDGFLAHLWAVTVTGAPKLAAVDFIEHAERSPRRWYGGAVGRL
                     GFDGTLDTVLTLRTVHILDGVAAVRAGATLLHDSSPEAEEAETELKARALLEVLDEPAV
                     RPAPVTRVRARGVGAGVRVLMVDHRDSFAHCLADHLRQTAAEVTTFRSGSHLPVLREQR
                     PDLLVLSPGPGRPEDFGMARTLAEAERLGVAVFGVCLGLQGMIEYCGGTLDVLGRPVHG
                     KPSAVRVTDPGSRLLAGLPEQFEVGRYHSLYAPVDSVPAELRVTAATEDGVTMAVEHRE
                     RPWAAVQFHPESIMSARGAAGRRIVDNAVSSLTAATLRQTGAARP"
     gene            complement(6968..8125)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="M878_RS60490"
                     /old_locus_tag="M878_11295"
     CDS             complement(6968..8125)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010474279.1"
                     /locus_tag="M878_RS60490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11295"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_023546234.1"
                     /transl_table=11
                     /translation="MTVSLGMPQTPRTLPEPLAPRRPTRQLRVGKVGVGSGSPVSVQSM
                     TTTPTADVNATLQQIAQLTAAGCDIVRVACPSQDDADALPQIARKAQIPVVADIHFQPR
                     YVFAAIEAGCAAVRVNPGNIKKFDDRIKDIARAAKEHGTPIRIGVNAGSLDRRLLAKHG
                     RATPEALVESALWEASLFAEHEFHDLKISVKHNDPLVMVRAYELLAERCDYPLHLGVTE
                     AGPAFQGIVKSAVAFGALLRQGIGDTIRVSLSAPPAEEVKAGTQILQALGLRPRKLDIV
                     SCPSCGRAQVDVYKLAAEVSAGLEGLQAPLRVAVMGCVVNGPGEAREADLGVASGNGKG
                     QIFVRGEVVKTVPESKIVETLIEEALRLAETTTEAGEPEVVTVGT"
     gene            complement(8161..9990)
                     /locus_tag="M878_RS60495"
                     /old_locus_tag="M878_11300"
     CDS             complement(8161..9990)
                     /EC_number="2.2.1.7"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951573.1"
                     /locus_tag="M878_RS60495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11300"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_023546235.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.2e-86,
                     bitscore: 288.5, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-07, bitscore:
                     30.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQLDEITGPADLRALSGAEVTELAAMIRRFLVEKVTRTGGHLGP
                     NLGVVELTIALHRVFDSPRDRILWDTGHQTYVHKILTGRAAGFDTLRRRGGLSGYPCRA
                     ESAHDVIENSHASTALSYADGLAKAYEIQGSTDRSVVAVIGDGALTGGMAWEALNNIAA
                     AKHRPLVVVVNDNGRSYAPTVGGLADHLAALRTGPRADAGHLGPRGLFEELGLAYLGPV
                     DGHDIEALESALTRAKRLGRPVVVHCLTEKGRGHRPAEQDEADRFHAVRAQPAAAAPAR
                     RERPSWTDVFGAELAELGAERPDLVAITAAMLAPTGLSRFAERHPERTFDVGIAEQHAV
                     TSAAGLALGGLHPVVALYATFLNRAFDQVLMDVALHRAPVTFVLDRAGATGDDGPSHNG
                     MWDLSLLQLVPGLRVAAPRDGATLRRALREAVAVDDAPTVVRFPKGSVGEDIPALDSCG
                     GVDILRRAEHPDVLLVAVGTMATTCLETADLLAGHGFGVTVVDPRWVKPVPSGLLELGR
                     EHRMVATVEDNGRVGGVGAAVAQALCDHGATAAVRTFGIAQDFPDHGARGDVLAGSGLT
                     SRHIARTLAEELAALDAVPRQGRPAPAAGHPAH"
     gene            complement(10047..11120)
                     /locus_tag="M878_RS60500"
                     /old_locus_tag="M878_11305"
     CDS             complement(10047..11120)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018840879.1"
                     /locus_tag="M878_RS60500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11305"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_023546236.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3e-44, bitscore:
                     150.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTTCSAPAARALKEARATILDGVERAVAALLAEERARWADDAP
                     QALVLLDAIGDLVAAGGKRLRPAFCASGFLLAGGSPDDPAAARLGAALELLHVSALIHD
                     DVLDESDRRRGLPTLHVARAAEHRRAGWRGSSERYGENAAILAGDLALTYADQLLAGFS
                     RPVLDEWSRLKSEMLVGQFLDVSVAAAYDPDPETSRRIAVCKSGHYSIHRPLTIGALLA
                     GRPDLAASFEAYGRALGEAFQLRDDLIDAFGDGEITGKPAGLDFAQHKMTLLLALAVRR
                     DARVRALVLPADGGIHAADADELRRLLTDSGVRAEVEERIDHLVTTAVDVLHQAPIDED
                     WRGELTEMAHRVAYRDH"
     gene            complement(11117..12136)
                     /locus_tag="M878_RS60505"
                     /old_locus_tag="M878_11310"
     CDS             complement(11117..12136)
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358319.1"
                     /locus_tag="M878_RS60505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11310"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_023546237.1"
                     /transl_table=11
                     /translation="MGSQQTQTAPDEDSGTRRIVLAEPRGFCAGVRRAVGIVERALDLY
                     GPPVYVRKEIVHNHHVVAELTERGARFVDSESEVPEGAVCVFSAHGVSPAVRRAAAERR
                     LDVIDATCPLVAKVHQEAVRYARDGRTILLVGHADHEEVEGTRGEAPERTLVVGTEEDV
                     ERLDLPDDAPVAYLTQTTLSLDETARVVDALRRRFTDLVGPHGDDICYASQNRQNAVKA
                     LARRSDLVLVVGSVNSSNSVRMVEVAREHGARAHLVPDVTFLDESWLESVTTVGISSGA
                     SAPEILVRGLAERLTELGYTGVETDRGASEDVVFALPARLATTAGDRVPSTPLAEEKP"
     misc_feature    12628..12637
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.31"
                     /tool="antismash"
     gene            12648..13562
                     /locus_tag="M878_RS97440"
                     /old_locus_tag="M878_11315"
     CDS             12648..13562
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024744.4"
                     /locus_tag="M878_RS97440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11315"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_023546238.1"
                     /transl_table=11
                     /translation="MNSHRRPPALRRVLLCAALASATLLAGPVGAVCLPTAPVAVARAQ
                     DSAVTVAGVLNFRDAGGYPTAFGPRMRTGVLYRSGALQNATDAGVQTLSDLHVTKVVDF
                     RTDAERTAAPDRLPAGASAALYPVSSTDRLQSFGQLLSMTADEQQALLGDGGAEEMMLQ
                     TAREFVTVPGKREQFGKALRDIADARGDDAVLVHCTGGRDRTGWLIAIVQTLLGVSRDD
                     VFADYLRSNTELASWKQGVLQQLAAGGMQDPGLVEPLLDVDASYLQASFDQAQQSYGSF
                     DAFVRDGLGIDDGTLARLRARLL"
     gene            complement(13673..16138)
                     /locus_tag="M878_RS60515"
                     /old_locus_tag="M878_11320"
     CDS             complement(13673..16138)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016906740.1"
                     /locus_tag="M878_RS60515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11320"
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="WP_023546239.1"
                     /sec_met_domain="PPDK_N (E-value: 3.7e-38, bitscore: 130.6,
                     seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNDRNDNTDAAPLVVSLDDPRALDRAEVGAKAAVLAQLRRSGFP
                     VPDGYVVTARAMVRHVRELAEVTAETVAGSPLDAGIRAAVQEVARRLDGPLAVRSSGID
                     EDGAHASHAGQYTTILDVEGAEALDEAVRACWASGFTEVVRGYRTAAGAEGDAPLAVLV
                     QRLVPAETAGVAFTVNPVTGARDEVLVSAVRGIGEQLVSGEVSPDDWAVPAGGTGTPVN
                     TAGRHGALTAGQAQEIATLAERVAEVLGGPTDIEWARAAGRLHLLQGRPITAIADPEPE
                     PVPVPVNAPRGFWAKDTTHAPLPLLPMTRELLDYNNTVLEGVCAQFGLLLKGLAFATIG
                     GWRYMATLPLSPADAPARIATCVAAVREDLAGQVIEEWLEEIRPRFADRIDALRRVDVT
                     ALSDEALAEHLAQVRALHRDGTEVHFRLLGAVSIALGRFGLFTTGTLGWEQGRVFELLT
                     GLSTESTGPALAMSELARTARQRLQGTPDLAALRTLLETDQEFAAAFETYRGEYGCRAL
                     QYELANPALAERPELILSLLRDQLGQDAALDHSGGAVEQARREAVAKAHAELAGGAEAE
                     RFGALLAGAERAYPVREDNEYWTVSAPNALLRWAALEAAGRLAGRGLLDRADHAFFLEV
                     EELRQALLESRDVRETVTRRRGEHRWALQNPGADSFGERPGPPPSMDALPAEVRETMGG
                     FAWTMQHMGGVSPAPRQGESGRLRGVPGSAGRYTGVARVVLSEGEFDKIRAGDVLVCPI
                     TSPVWSVVFPSIGALVTDTGGALSHAAIIAREYGIPAALATGNATQILRDGMLVTVDGS
                     SGVVEIHEQ"
     gene            complement(16443..17186)
                     /locus_tag="M878_RS60520"
                     /old_locus_tag="M878_11325"
     CDS             complement(16443..17186)
                     /NRPS_PKS="Domain: Thioesterase (16-227). E-value: 2.4e-23.
                     Score: 75.7. Matches aSDomain:
                     nrpspksdomains_M878_RS60520_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="M878_RS60520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11325"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_023546240.1"
                     /sec_met_domain="Thioesterase (E-value: 1.5e-23, bitscore:
                     83.2, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.3e-09, bitscore:
                     37.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAGPERVVLQEGRGFHLVCLPFAGGSARSFVRLARHIPRDWRVT
                     AVQPPTGFAPGPAGLDALASFYLGLLAADLREPALVLGHSLGAAVAHRMAWLRAAPPSE
                     SLHLVLSAPPRPHHSPAGLLELDDRALFREATRQGMLPDLNTSEDFALRFLVPNLRQDL
                     ALLDRRGWAPEPLDTPLHLLGGTDDVACPPAALARLGDVLTPRSTRLVEGGHMYVLERP
                     AETAQALVEISREVTAHPAPTLAAG"
     aSDomain        complement(16506..17138)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS60520_Thioesterase.1"
                     /evalue="2.40E-23"
                     /label="M878_RS60520_Thioesterase.1"
                     /locus_tag="M878_RS60520"
                     /protein_end="227"
                     /protein_start="16"
                     /score="75.7"
                     /tool="antismash"
                     /translation="HLVCLPFAGGSARSFVRLARHIPRDWRVTAVQPPTGFAPGPAGLD
                     ALASFYLGLLAADLREPALVLGHSLGAAVAHRMAWLRAAPPSESLHLVLSAPPRPHHSP
                     AGLLELDDRALFREATRQGMLPDLNTSEDFALRFLVPNLRQDLALLDRRGWAPEPLDTP
                     LHLLGGTDDVACPPAALARLGDVLTPRSTRLVEGGHMYVLERPAETAQ"
     CDS_motif       complement(16902..16955)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS60520_0001"
                     /evalue="1.40E-05"
                     /label="NRPS-te1"
                     /locus_tag="M878_RS60520"
                     /protein_end="95"
                     /protein_start="77"
                     /score="17.7"
                     /tool="antismash"
                     /translation="PALVLGHSLGAAVAHRMA"
     gene            complement(17183..18733)
                     /locus_tag="M878_RS60525"
                     /old_locus_tag="M878_11330"
     CDS             complement(17183..18733)
                     /GO_function="GO:0016405 - CoA-ligase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: AMP-binding (20-416). E-value: 1.6e-91.
                     Score: 298.8. Matches aSDomain:
                     nrpspksdomains_M878_RS60525_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016906742.1"
                     /locus_tag="M878_RS60525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11330"
                     /product="benzoate-CoA ligase family protein"
                     /protein_id="WP_023546241.1"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-97, bitscore:
                     325.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGPETATNAGWWYLDRHLSAGNGDRVSLVTKEGELTYSRLHERV
                     CRTARVLAEARIAPGDRVVTVLPDGVDAVACVLAAMRLGAVPVPVSPMLPLDDQREVVA
                     DCGPRAVVVQDAEGELARELTEHAPDVRVWSAGPGAGPVTSLAEATTGATPLWTVRARD
                     GRDPALIQYTSGSTGRPKGVVHLHRGLLAFPRTFGRHLGITSEDRVLSTAKLPFGYGFG
                     NSLLLPFSVGASAVLFAGRFEPHAVAGLVARTRPTLLFAVPTLYAALLSMPDAARRLDL
                     SSVRLAVSAGEHLGPQLSTRLTETLGLTVVNGLGSTECLHIFLATVPGVSPAGSTGIPV
                     PGFEAEVCDDEGRPLEQGGIGHLRVRGPSVADRYWNRPDLSAETFRDGWVHTGDTMTHD
                     PEHGWVYLGRSDNILNVGGMKILPSEVEDAVLAVPGVGSCAVVGVPDQDDVVRIVAHVV
                     PEDGVGEELRGQVLAALRRTLPPFKRPHTVRLTDALPTTSTGKTARFLIRRREMEGQT"
     aSDomain        complement(17486..18673)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS60525_AMP-binding.1"
                     /evalue="1.60E-91"
                     /label="M878_RS60525_AMP-binding.1"
                     /locus_tag="M878_RS60525"
                     /protein_end="416"
                     /protein_start="20"
                     /score="298.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AGNGDRVSLVTKEGELTYSRLHERVCRTARVLAEARIAPGDRVVT
                     VLPDGVDAVACVLAAMRLGAVPVPVSPMLPLDDQREVVADCGPRAVVVQDAEGELAREL
                     TEHAPDVRVWSAGPGAGPVTSLAEATTGATPLWTVRARDGRDPALIQYTSGSTGRPKGV
                     VHLHRGLLAFPRTFGRHLGITSEDRVLSTAKLPFGYGFGNSLLLPFSVGASAVLFAGRF
                     EPHAVAGLVARTRPTLLFAVPTLYAALLSMPDAARRLDLSSVRLAVSAGEHLGPQLSTR
                     LTETLGLTVVNGLGSTECLHIFLATVPGVSPAGSTGIPVPGFEAEVCDDEGRPLEQGGI
                     GHLRVRGPSVADRYWNRPDLSAETFRDGWVHTGDTMTHDPEHGWVYLGRSDNILNV"
     CDS_motif       complement(17579..17662)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS60525_0002"
                     /evalue="1.20E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="M878_RS60525"
                     /protein_end="385"
                     /protein_start="357"
                     /score="27.2"
                     /tool="antismash"
                     /translation="GGIGHLRVRGPSVADRYWNRPDLSAETF"
     CDS_motif       complement(18173..18232)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS60525_0001"
                     /evalue="5.90E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="M878_RS60525"
                     /protein_end="187"
                     /protein_start="167"
                     /score="25.0"
                     /tool="antismash"
                     /translation="ALIQYTSGSTGRPKGVVHLH"
     gene            complement(18730..>19212)
                     /locus_tag="M878_RS47550"
                     /pseudo=""
     CDS             complement(18730..>19212)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS47550"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="GATEPHLARMLGTCQVTAEPADTDPDASRALARAAEEAVLDALRT
                     ADRFAAEVGCAVTVTGGDAVAGTAVRMALDTVFGPKLPVCDPLAATGHCGGADGAVAVV
                     VAVEALARGVVPAAPDRGDAPAAPIGPLALCLGVDRGGSATAVLVGPPAPHPGEAA"
     misc_feature    complement(19163..19173)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     assembly_gap    19213..20000
                     /estimated_length=788
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     gene            complement(<20001..20465)
                     /locus_tag="M878_RS47555"
     CDS             complement(<20001..20465)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: ketoacyl-synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS47555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="beta-ketoacyl synthase N-terminal-like
                     domain-containing protein"
                     /protein_id="WP_031224686.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 0.00014, bitscore:
                     20.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTPNPSPPSTGAVITAAGAVTACGTSVARLFEDLLDGRRPFTTQ
                     GVPLVANPLPAAHPERATADDTDPEVFAGHVRTPLDLTDVAGARAARAMSRDARLLLYA
                     AHAAGVREAVDPDRTGVVLGTLHAGRNEYLAIHNASQGAGGPVNPVWGPQS"
     gene            complement(20549..21766)
                     /locus_tag="M878_RS60530"
                     /old_locus_tag="M878_11345"
     CDS             complement(20549..21766)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (85-404). E-value:
                     3.6e-50. Score: 163.0. Matches aSDomain:
                     nrpspksdomains_M878_RS60530_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: ketoacyl-synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: hr-t2pks-ksa"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012337.4"
                     /locus_tag="M878_RS60530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11345"
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_031224687.1"
                     /sec_met_domain="hr-t2pks-ksa (E-value: 3e-95, bitscore:
                     318.5, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 6.7e-38, bitscore:
                     129.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRDTRGRHRVVVTGLGLATPLGTEVEEFWRNVTAGTVATAPVTR
                     FPTDGYPTHLAAEVTDPALTAPLTSDGRSVPRSLRYVHHSVDAALRDAGLLGHPGLART
                     GIVVGTVMGTRPHLEELRRQGRPLTEDFSWDSPQSLAREPGRAFGLRGPRQVVAAGCAA
                     GNTALAMAADAIRSGQADAMVAGGVDELSESVYRLFTTLRALAPDAVRPFDRDRRGMMP
                     SEGAGVLVLESLEHAVRRGATVLAELPGYALAADAHHMTAPHPQGLGMLRCMQDSLEQA
                     GIDPREVDYVSAHGTGTPANDSLEAACLAEYFGSRGGTPAVSSIKGLMGHSQGGASAVE
                     AIACVLAIRDGRVPGNPTLREADESCAGLDVVRGPARDMPVRVTLSNAFGFGGNTSAIV
                     LARYPD"
     aSDomain        complement(20555..21511)
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS60530_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="3.60E-50"
                     /label="M878_RS60530_PKS_KS.1"
                     /locus_tag="M878_RS60530"
                     /protein_end="404"
                     /protein_start="85"
                     /score="163.0"
                     /tool="antismash"
                     /translation="VDAALRDAGLLGHPGLARTGIVVGTVMGTRPHLEELRRQGRPLTE
                     DFSWDSPQSLAREPGRAFGLRGPRQVVAAGCAAGNTALAMAADAIRSGQADAMVAGGVD
                     ELSESVYRLFTTLRALAPDAVRPFDRDRRGMMPSEGAGVLVLESLEHAVRRGATVLAEL
                     PGYALAADAHHMTAPHPQGLGMLRCMQDSLEQAGIDPREVDYVSAHGTGTPANDSLEAA
                     CLAEYFGSRGGTPAVSSIKGLMGHSQGGASAVEAIACVLAIRDGRVPGNPTLREADESC
                     AGLDVVRGPARDMPVRVTLSNAFGFGGNTSAIVLARYP"
     gene            complement(21756..21998)
                     /locus_tag="M878_RS60535"
                     /old_locus_tag="M878_11350"
     CDS             complement(21756..21998)
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (8-74). E-value: 4.7e-15.
                     Score: 47.7. Matches aSDomain:
                     nrpspksdomains_M878_RS60535_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="M878_RS60535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11350"
                     /product="acyl carrier protein"
                     /protein_id="WP_023546243.1"
                     /sec_met_domain="PP-binding (E-value: 1.9e-11, bitscore:
                     43.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNETEIRAVVTDVVAGVLTLPTEQVPPQARFYDDLGGDSLQKLEI
                     VAHIESRFNCSLTHEQVAVSDTVEDLCRQVARHVA"
     aSDomain        complement(21777..21974)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS60535_PP-binding.1"
                     /evalue="4.70E-15"
                     /label="M878_RS60535_PP-binding.1"
                     /locus_tag="M878_RS60535"
                     /protein_end="74"
                     /protein_start="8"
                     /score="47.7"
                     /tool="antismash"
                     /translation="VVTDVVAGVLTLPTEQVPPQARFYDDLGGDSLQKLEIVAHIESRF
                     NCSLTHEQVAVSDTVEDLCRQ"
     gene            complement(21995..23059)
                     /locus_tag="M878_RS60540"
                     /old_locus_tag="M878_11355"
     CDS             complement(21995..23059)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013226.4"
                     /locus_tag="M878_RS60540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11355"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_023546244.1"
                     /transl_table=11
                     /translation="MTAPLTAPAHRVRPPTARRAVLLLLRSCSVRFTAYYWVGFAAGLA
                     ATGHLGPGLALLGVPMWLAYCVGTESVNRIADRAADEVNRPERTRLCEEFGWSRLTAVA
                     VLSWTVFVLIGAALTWRHPGFALPALLLVDIGVAIGYSIGPAFKRHRVLALLALTAPLI
                     TPLLTGWAVYGGYDTLLSPVLPAVSVLAAFSLGLSGIKDITDVEGDRRLGYSSLWLSVA
                     RIGRGAAVYAFIGAPFLLLALYAALHVLPLPALALLPLVAVSALVVTAASRAVAPLDRE
                     AAREVMHQYTFYFLALCLTACAPTRAAAAAAAAGIAYWLVASKTLHWSGGLTLSHLRRW
                     VRLFGPALTVKEHS"
     gene            complement(23061..24335)
                     /locus_tag="M878_RS60545"
                     /old_locus_tag="M878_11360"
     CDS             complement(23061..24335)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="M878_RS60545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11360"
                     /product="cytochrome P450"
                     /protein_id="WP_023546245.1"
                     /sec_met_domain="p450 (E-value: 2.1e-17, bitscore: 62.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQTEVSASSGAGVAELPFNPADPSFQADPFPAYRVLRDRFPVLR
                     GPLGAFLVSRYEDCELLLRDRRMGKDFANSKFFQQIMGEAGDEPPPFLGLGLDDWDAKL
                     FMLTDPPEHTRLRGLVGQAFTPAMIRNLRSAVTAIVEELLGELPERFDLMERLATPMPI
                     RVLGTMLGIPAEDQAQFTTWSTEIAGLLDLDVALPPEVAEARRTAVAACTSYFLELAAR
                     RAGGDGEDLVSQLVRARDQGSALTTQEIAATCVLLVVAAQETFSNLLGNAAVVFARQPE
                     AFTRIAERPETTDATLEEILRLEPPAHQVGRIALERMELHGEVIEPGDAVILLVASANR
                     DERAFPAPDAVDIGREGRNHLSFGRGIHYCLGAPLATMMAKEALRGLTVRITSLALAEE
                     PIAYKPGMGLRGPARLPVVVRKRVS"
     misc_feature    complement(24410..24427)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.16"
                     /tool="antismash"
     misc_feature    complement(24420..24435)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.74"
                     /tool="antismash"
     gene            complement(24589..25935)
                     /locus_tag="M878_RS60550"
                     /old_locus_tag="M878_11365"
     CDS             complement(24589..25935)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135297.1"
                     /locus_tag="M878_RS60550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11365"
                     /product="3-deoxy-7-phosphoheptulonate synthase class II"
                     /protein_id="WP_031224690.1"
                     /transl_table=11
                     /translation="MTTAPVPRTAHSTWRDLTAAQQPRWPDPALLAAVTAELARAPELV
                     SAEESDRLTARLADVTHGRAFVLMGGDCAETFTGTTTDSVRRKLRTLLQMAVILTYAAQ
                     VPVVKVGRMAGQYAKPRSRPTETRDDVTLPAYRGDAVNGLEFSPASRTPDARRLRRMYD
                     SSAATLNLVRAFATGGSADLREAHAWNQGFVRDSPAGRRYEDLAGEIDRSLRFMKACGV
                     DPHATRGVEFFAGHEGLLLDYEDALTRTDPRTGLSYATSGHFLWIGERTRDLDGAHVDY
                     FARIRNPIGVKLGPSVTADEALAYADRLNPGNSPGRLTFVTRMGASRIRDVLPGLVEKV
                     TANGVAVTWVCDPMHGNTFEATSGHKTRRFDDILDEVSGFFEVHRALGTHAGGVHVELT
                     GDDVTECLGGADGLLVQDLHRRYETACDPRLSHRQSLELAFLLAQMLRD"
     gene            complement(26004..26903)
                     /locus_tag="M878_RS60555"
                     /old_locus_tag="M878_11370"
     CDS             complement(26004..26903)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044908.1"
                     /locus_tag="M878_RS60555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11370"
                     /product="acyl-CoA thioesterase II"
                     /protein_id="WP_063750620.1"
                     /transl_table=11
                     /translation="MSETRAAEKNAATSPLLEILDLEEIEAGVFRGHSPAAAPPRVFGG
                     QLLAQALTAASRTVPGGRTAHAAQIVFLRGADPARPLDFHVQDLHDGRSFGVRQVAVRQ
                     GERAVCTVTVSFQDTEQGPEHAVTAPAAPPPDRWPTYAHALGPMSGRLGAIPDVVRPFD
                     LRYETEPPWAGAARGPGRPAHRAWLRAVERLPDTPLSHQAALAYATDLTLVDSILLGHG
                     VYWGLDPVTMVSLNHSVWFHRPFRADTWLLYDCESPTAGQGRGLACGRFFDEDGRLVAS
                     VVQEALFRLGPRGHEGAR"
     gene            complement(27034..27738)
                     /locus_tag="M878_RS60560"
                     /old_locus_tag="M878_11375"
     CDS             complement(27034..27738)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (120-176). E-value: 1.3e-06. Score:
                     20.2. Matches aSDomain: nrpspksdomains_M878_RS60560_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013786.4"
                     /locus_tag="M878_RS60560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11375"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_158692679.1"
                     /transl_table=11
                     /translation="MRAPVPQGRVSSLADAVRALRPLLSAQGLALGLAGTEETALLPGG
                     PAERGLARCMGAARRQEFLAGRWALRRALDAVGCPAPDISYEGRRPKVPDRTVASLTHS
                     GGTAVALAARRDTCRTVGVDLELHQLPLEAAHLVLTPREAGWLEATAAGDPAAARRLLH
                     TVFSAKEAVFKALAALPGGAASPRTLRDIAVRPVPHGFEAWQHGQAGPVLRTRVRWVAG
                     AVLCWTVLPAAG"
     aSDomain        complement(27211..27378)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS60560_ACPS.1"
                     /evalue="1.30E-06"
                     /label="M878_RS60560_ACPS.1"
                     /locus_tag="M878_RS60560"
                     /protein_end="176"
                     /protein_start="120"
                     /score="20.2"
                     /tool="antismash"
                     /translation="VGVDLELHQLPLEAAHLVLTPREAGWLEATAAGDPAAARRLLHTV
                     FSAKEAVFKAL"
     gene            complement(27743..29137)
                     /gene="pcaB"
                     /locus_tag="M878_RS60565"
                     /old_locus_tag="M878_11380"
     CDS             complement(27743..29137)
                     /EC_number="5.5.1.2"
                     /GO_function="GO:0047472 - 3-carboxy-cis,cis-muconate
                     cycloisomerase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="pcaB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467090.1"
                     /locus_tag="M878_RS60565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11380"
                     /product="3-carboxy-cis,cis-muconate cycloisomerase"
                     /protein_id="WP_023546249.1"
                     /transl_table=11
                     /translation="MKDMADTGLLSPVRAGTEVEAAVSDRAWLQAMLDAEAALARAQAK
                     LGTLPVLAAEAITRAADATRFDLREIALAARETANPVVALVQSLTRLVAAEVPAAADYV
                     HRGSTSQDIFDTGAMLVVRRALTVIRADLARAAEALARLAAEHRDTPMAGRTLALQAVP
                     TTFGLKAAGWRQSLLDAEERLARVAGQHLPVSLGGAAGTLAGYLEYAGIGGVRRTPEEY
                     VTDLEEAFAAETGLSRPALPWHALRTPIADVAAALAFTAGALGKIAVDVQNLTRTELGE
                     VSEPFVPGRGSSSAMPHKRNPVLATLIRTAALQVPVLAAGLTQCLLAEDERSGGAWHAE
                     WQPLRECLRLVGGAAYTAVELAEGLRVHPDRMRENLARTGGQLVTERIAARLVPALGKA
                     RARELVDEASTTARTLDRPLHQVLAELPEVRAALAPAELTGLVDPDSYVGAAGALVDRA
                     VGPRPR"
     gene            complement(29134..31092)
                     /locus_tag="M878_RS60570"
                     /old_locus_tag="M878_11385"
     CDS             complement(29134..31092)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NpaA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609606.1"
                     /locus_tag="M878_RS60570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11385"
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="WP_023546250.1"
                     /sec_met_domain="NpaA (E-value: 3.9e-227, bitscore: 754.6,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSSALALCIVGAGPRGLSVLERLCANARMTPTHSAVTVHVVDPG
                     TPGAGAVWRPEQSRLLLMNTVASQITVFTDKSVRIDGPVEPGPSLYEWARRLAGGGFGA
                     CDDQTLAEARDLTPDSYPSRAFYGCYLRDMFQRVVRDAPAHVTVRTYRQRAVAVTDLSG
                     EHRGAQAVRLEDGTWLEPLDAVVLAQGHLANRPTAREERHAQLARVHGLTYLPPANPAD
                     VDLDVIAPGEHVLLRGLGLNFFDYMALLTTGRGGTFARDGAERLVYRPSGNEPVLFATS
                     RRGIPYHARGENEKGAHGRHHPRLLTADHVTALRGSRPPGEGLDFRRDLWPLIAREVES
                     VYYGALLAARGRGADRERLVTGYLHADETELPGLLDAYGITAEERWNWARLERPYAGRT
                     FADRADFQAWLSAHLAADVRQARGGNVSNPLKAALDVLRDLRNEVRLAVDHGGLDGDSH
                     RDDLDRWYTPLNAFLSIGPPASRIEETAALIEAGVLELTGPDTVIRIDLRSSTYVTTST
                     AVPGPPVRATALIEARIPDADVRRTADPLLLHLLGTGQATTHRISAACGTTYHTGGLAV
                     GTRPYRLLDAQGREHPRRFAYGVPTESVHWATAAGIRPGVDSVTLGDSDAVARAVLELE
                     PTVDAPVPDADITGVII"
     gene            complement(31374..32447)
                     /locus_tag="M878_RS60575"
                     /old_locus_tag="M878_11390"
     CDS             complement(31374..32447)
                     /codon_start=1
                     /gene_functions="regulatory (extras) StrR_like: StrR-like
                     pathway specfic regulators"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970238.1"
                     /locus_tag="M878_RS60575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11390"
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="WP_051430077.1"
                     /transl_table=11
                     /translation="MVMADDVQQAAHEAERARASAEDRLSEVHRVPVASLRPGRSPRVN
                     AEDEEHVRLLADSDEARPPLVVHRATMEVVDGRHRLKAAVLRGETEIEVRFFDGSAEDA
                     FVFAVRTNVRHGLPLSLADRRAAAVRILGSHPEWSDRAIARVTGLSSKTVGAQRHKLGD
                     LGEATTRVGRDGRGRPLNSAEGRRIAGRLILESPHASLRAIAKQAGVSPGTVRDVRARL
                     DRGDDIVPSHRRGEKPTTPPAPQSAPRPQPWSVVAPGWETDERPRQPMVDNLDWIDMFR
                     RMCRDPSLRLTEDGRQLLRMMEMHVLHPQRWDSIARSVPRHRAQVVSALAMECAQQWHR
                     FAARIEAGEVTVTSVAS"
     misc_feature    complement(32484..32501)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.2"
                     /tool="antismash"
     gene            32724..33341
                     /locus_tag="M878_RS60580"
                     /old_locus_tag="M878_11395"
     CDS             32724..33341
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268979.1"
                     /locus_tag="M878_RS60580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11395"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_037730097.1"
                     /transl_table=11
                     /translation="MIQSRAVRTRQELIRAAAEAFALRSYHQATIADISEAAGVSPGGL
                     HFHFTNKAAIAEAVEDEAAQLLRATCRDARSGAHTSLQALIDASHAIAALLSGNIVARA
                     GLLLGQEPTRSSKLSLHQEWAECIHLLVRRAVEEGQLSSDVSPRDLYTAVLAATVGLEA
                     LGRGDGRWLTPQTLASFWRLLLPRICPPHRAVHLNPTGTAAR"
     cand_cluster    32756..43697
                     /candidate_cluster_number="4"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="3"
                     /tool="antismash"
     protocluster    32756..43697
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[37755:38697](-)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      complement(37756..38697)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="3"
     misc_feature    complement(33351..33369)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.19"
                     /tool="antismash"
     gene            33424..34866
                     /locus_tag="M878_RS60585"
                     /old_locus_tag="M878_11400"
     CDS             33424..34866
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="M878_RS60585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11400"
                     /product="MFS transporter"
                     /protein_id="WP_031224696.1"
                     /transl_table=11
                     /translation="MALTRSDSSAASEAVQPPPGSREWRVLSVALIAAFMAVFDLYVVN
                     IAAPTLRTDLHAGDASLELVVSGYAFTYAAGLVTGGRLGDRFGYRTMFVAGMAAFSVAS
                     LLCALATTPGQLVAARLLQGLTAAAMVPQVLALITVTFPAAHRARATGWYGAVSGLGAL
                     CGQILGGLILKADLFGLGWRGIFVVNVPVGVIAVALGLTVLPRTPAAQKAKFDPIGALT
                     VSLALALVLVPLSLGRESGWPLWTWLCLIASVPVMFAAIAWQRSLLRRGGAPIINTALF
                     RNRPYSLMLSAASTYQLYFGSFLFALTLVVQSWLGTSPDRAALVFLLQGVLFTVASMVG
                     GKLIARYRTGVPVVGGVLVIAGLLLITGELAAGGPGLSAWWLVPPLAVIGLGNGLLLPP
                     LIGGALSRVQPEQAGAASGTLNTAQQFANSLGVTVIGTVFFALAGPALHSAGHAMEILN
                     VVYALLTAAVIALVKLADRAGR"
     gene            34972..36030
                     /gene="trpD"
                     /locus_tag="M878_RS60590"
                     /old_locus_tag="M878_11405"
     CDS             34972..36030
                     /EC_number="2.4.2.18"
                     /GO_function="GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640529.1"
                     /locus_tag="M878_RS60590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11405"
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="WP_023546254.1"
                     /transl_table=11
                     /translation="MSAQSQGRSWPKLLDSLLRRSDLHARDTAWAMDQVMSGAAPPAAL
                     AGLLVALRAKGETVEEVEGLVRSAYRHALPLEIAGPALDIVGTGGDGSDSVNVSTMSAI
                     VAAGAGARVVKHGNRSASSACGSADVLEELGVVLDLSPQDVRDVAEDVGITFCFARLFH
                     PAMRHAAPTRRSLGVRTVFNLLGPLCNPARPSAQAVGVADPAAAPLIARVLARRGVSAL
                     VFRGDDGVDELSVTTTSAIWSVTGSGIRSETFDPRDIGFTLASPDALRGGDPAHNARVA
                     RDILAGEQGPVRDAVLLSAAAGLAALEPCDRPVAERLEDGVRRAAASIDSGAAASILER
                     WVAVTVKRALDA"
     gene            complement(36103..36966)
                     /locus_tag="M878_RS60595"
                     /old_locus_tag="M878_11410"
     CDS             complement(36103..36966)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268973.1"
                     /locus_tag="M878_RS60595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11410"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_023546255.1"
                     /transl_table=11
                     /translation="MILITGASGTVGRLTARTLMRSGHPVRLLVRDAVRAPAPEPGAEA
                     QVAIGDFDAPETLRRAMTGVRAVLVITSDPTRPEQDAHLVRAAADTGVRHLVKLSALAA
                     TQARARDLVTRWQRESEDRIRASGSDWTLLRPRAFMTNTLAWAAEVKATDTVRHWPGDV
                     PSACVDPADVAAVAARVLTEDGHAGRAYPLTGPEALTAREQTRILSGALGRPLSFAERS
                     REETLAMLHRRYPEPVAQALVDRADGRSADAKGGVADTVARLLGRPAGTYAAWIERSLR
                     AFARGT"
     gene            complement(36983..37759)
                     /locus_tag="M878_RS60600"
                     /old_locus_tag="M878_11415"
     CDS             complement(36983..37759)
                     /NRPS_PKS="Domain: PKS_KR (11-191). E-value: 9.2e-17.
                     Score: 53.5. Matches aSDomain:
                     nrpspksdomains_M878_RS60600_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542397.1"
                     /locus_tag="M878_RS60600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11415"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_023546256.1"
                     /sec_met_domain="adh_short (E-value: 1.5e-32, bitscore:
                     112.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 2.7e-29, bitscore:
                     101.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHSQGMLAGKVVMITGASSGIGAAAARVFSAEGARVVLMARNPE
                     PLEALAREITATRGPAHAVAGDVTSAQDVRRVVEAAVETYGRLDGAFNNAGWGAPRTPL
                     HLTEDSEYDRVFDVNVRGVWNCLRRQIPAMIATAGGGAVVSSSSTAGVVGHFLPGAPYI
                     AAKHAVIGLTKAAADQYGSQGIRANVLAIGATRTELLQEALDQYPGLEDRLASESMVGR
                     LAEPEEVARAAAWLLGDGSSFVTGATVPVDGGVTAR"
     aSDomain        complement(37187..37726)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS60600_PKS_KR.1"
                     /evalue="9.20E-17"
                     /label="M878_RS60600_PKS_KR.1"
                     /locus_tag="M878_RS60600"
                     /protein_end="191"
                     /protein_start="11"
                     /score="53.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVMITGASSGIGAAAARVFSAEGARVVLMARNPEPLEALAREITA
                     TRGPAHAVAGDVTSAQDVRRVVEAAVETYGRLDGAFNNAGWGAPRTPLHLTEDSEYDRV
                     FDVNVRGVWNCLRRQIPAMIATAGGGAVVSSSSTAGVVGHFLPGAPYIAAKHAVIGLTK
                     AAADQYGSQGIRANVLA"
     CDS_motif       complement(37631..37720)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS60600_0001"
                     /evalue="5.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="M878_RS60600"
                     /protein_end="43"
                     /protein_start="13"
                     /score="12.7"
                     /tool="antismash"
                     /translation="MITGASSGIGAAAARVFSAEGARVVLMARN"
     gene            complement(37756..38697)
                     /locus_tag="M878_RS47560"
                     /old_locus_tag="M878_11420"
     CDS             complement(37756..38697)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041195.1"
                     /locus_tag="M878_RS47560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11420"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_158692680.1"
                     /sec_met_domain="AfsA (E-value: 1.3e-17, bitscore: 62.6,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRRNGEQVLVTGVEQCEENRFNVSVHWPRDHRFYGPCADGGSDP
                     QLVSETMRQAGILVGHVAYDVPKGHSFVMNELSHTVDWEALAPADTRTRLDLEVNCLEV
                     RRRGRTLFGVRGTMVLRREGREVASGTFDYRCMSPGVYRRLRAEARSSEDPALPALPAP
                     VEPVAVGRVRPQDVVIASSGLPGTFLLRAERDHPVLYDHPLDHVPGMAIIEAMRQTAQA
                     VTGLSGAVTARMQTAFSHYVEHDLPCYLTTGTPTRPDGGAVEVPVQVWQRDQEAARGVI
                     PLSPCGDGLELTFLPYPSEQRQPVLQLAGRAV"
     misc_feature    38817..38830
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.49"
                     /tool="antismash"
     misc_feature    complement(38817..38831)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            38996..39625
                     /locus_tag="M878_RS60605"
                     /old_locus_tag="M878_11425"
     CDS             38996..39625
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602525.1"
                     /locus_tag="M878_RS60605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11425"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_023546258.1"
                     /transl_table=11
                     /translation="MRTRRKLIDAAAAVISKRGYRAATIADIMEAGDVTRGALYFHFSS
                     KRALADAIIQEQTLPYTVTAPGSPLQRLISMSLEIGRGLQNDPLLRAGTRITVDTVFDD
                     APVTPFEEWNTVAVALLTEARDAGELLPHIDPGTCGEFIVAAFTGVQLFSQAASGHADL
                     SERITNLWRLLLPGIAHPAAITYLNPTFPDSRPGAPADQPLEPSDA"
     misc_feature    complement(40664..40677)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.28"
                     /tool="antismash"
     misc_feature    complement(40858..40873)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.66"
                     /tool="antismash"
     gene            40960..41904
                     /locus_tag="M878_RS60615"
                     /old_locus_tag="M878_11440"
     CDS             40960..41904
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481457.1"
                     /locus_tag="M878_RS60615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_11440"
                     /product="hypothetical protein"
                     /protein_id="WP_031224700.1"
                     /transl_table=11
                     /translation="MSETGASPLPSTPPARSPLFRAEQFVWLNARVLEQHLFAYRFLHG
                     TPDAVEAALDAYRNEDGGYGHGLEPDLRGPMSQPLHTAHALRVLDAIGRCGGQRVERVC
                     RYLTSVSTADGALPAIRPSQRGYPTAPFVPVVDDPPSELLATGPVVGLLHRNEVWHAWL
                     FRATDFCWQAVESLGKSHPYEVEAAVAFLDSAPDRSRAEAAADRLGRMVREQRLAVLDP
                     DRLDAYPVASGYAPGEHHFPHDFARSPESFARAWFTDDEMARSLDHLAAEQQDDGGWPI
                     SWRQWAPAPALEARSLVTIEALQTLRSYGRFVG"
ORIGIN
        1 tagcgcagat ggtgggcgag atgttcgtcg aacccgaagt tggcggcctc cagcggtacg
       61 agcgaggtga ccacgttcca gcctgcccgg ccccccgaca gctggtcgag ggaggcgaac
      121 cggcgggcaa ggtcggccgg ggcgttgtag gtggtggtgg ccgtggccac cagaccgatg
      181 tgctcggtga ccgaggagag cgcggacagc acggtcagcg gctcgaagta ggaggcccgg
      241 ccggtgcggc tgagtgtctc ggcgtcctcg ccccaggtgg cgaggacgtc ggcgacgaac
      301 agcacgtcga acctggcgtt ctccagggtc tgcgcgagac gggcacggaa gtcgaagtcc
      361 agttgcccat cggcgcgggc ctgcggatgc cgccaggccg cgacatggcc accggatccg
      421 tggatgagag cgcccagtga catcgtgcgg gggcgccggg ctgtcgtcat acgagttcct
      481 cgtgtgcgtg aacggagcga aggggcaggg gtgagaggtg caggggtgag ggggcggcac
      541 gccgcgcagt ggcagcgggg gccggcgaag gggcccgccg cggggcgccg gagccggaag
      601 ccgccggccg ctcccccaac gaagatcgtt tgatggtgac cctaggccgc acgcgcctcc
      661 cctcaaagtg gtcagcacgc tgggcgactt ggcggcgcga cagcactgcg gatgtgcgac
      721 cggggaaatt ccccggtcgc acaggagggg tcaccgccgt cgcgatatca tcaacattcc
      781 ctatccacca acatgagcaa ggtgcggatc atgaagctgt cgcagggagt ggagtgggct
      841 ctgcactgca cggtggcgct ggcgcagtcc agggcccagg cgcccgtctc acggcggacc
      901 ctggcggggt acttcgacct tccggaggcg tacctcgcca agcacctgaa gtccctcgtg
      961 caggccgggg tgctgaccgc gacctccgga ccgcgcggcg gcttccggct cgctcgcccg
     1021 gcgtcgggga tcaccgctct ggacatcgtg gaggcgatcg agggcaccct gccgcccttc
     1081 gtgtgcacgg agatccgcca gcgcggcgaa tgcgcggtgc cgccggagaa gtgcactggc
     1141 ccctgcccgg tggcgaaggt catgtacgac gcggaccggg cctggcgcga ccatctgcgc
     1201 tcggtcaccg tggccggtct ggtcgaccgg ctgccgccct ggtcccacag ccacgccggg
     1261 acgcccaccg aggcggacgc ctccacggtg ctnnnnnnnn nnnnnnnnnn nnnnnnncag
     1321 ccgatgactg tccaggtgtc cccgcctgcc aggagtgcgg cgaggtcgcc cttgcctttc
     1381 tgttcgatgg cggtgtcgag ctggtcggcc atcgcggtgt cgtagacggg gcgttcgacg
     1441 gagcggaaga ctccgatcgg ggtctggtgc agggtgtcgg ggtcggcgag gcgggacagt
     1501 gcgaaggcgg tggtcgggga ggtggcgtgg gcgtcgtgga ccaggatgtc cgcctcgttg
     1561 tccgcggtga cggtgacggc ctccaggtcc ccggtggccc ggttgcgcac gacaccgcgg
     1621 gcgccgtcgg tgccgaaacg gatcggctgt ccgtgttcca ggcggatcag tgcctcctgg
     1681 gcctgctgcg tgtctttcag ggcgtcgaag gcgccgtcgt tgaagatgtt gcagttctgg
     1741 tagatctcga tcagggcggt gccggggtgg tcggcggcct ggcgcaggac ctcggtcagg
     1801 tgtttgcggt cggagtcgat ggtgcgggcg acgaaggacg cttccgcgcc gatcgccagc
     1861 gagaccgggt tgaacggggc gtccagggag cccatcgggg tcgatttggt gatcttgccg
     1921 agttcggagg tcggcgagta ctggcccttg gtcagaccgt agatccggtt gttgaacagc
     1981 aggatcttca ggttgacgtt gcggcgcagg gcgtggatga ggtggttgcc gccgatggac
     2041 agcgcgtcgc cgtcaccggt gaccacccac acgctcaggt cccgcctgct ggtggccagg
     2101 ccggtggcga tggccggggc gcggccgtgg atggagtgca tcccgtaggt gttcatgtag
     2161 tacgggaagc gggaggagca gccgatgccg gagacgaaga cgatgttctc cctggccagg
     2221 cccagctcgg gcatgaagcc ctggacggcg gcgaggatcg cgtagtcacc gcagcccggg
     2281 caccagcgca cctcctggtc cgacttgaag tccttcatcg actgcttggc ctcggccttg
     2341 gggaccagct gcagcagccc gcctgcggtg tcagtcatcg atggcctcct tcaaagccct
     2401 ggcgagctgt tccgccttga acggcatgcc gttgacctgg ttgtaggagt gggcgtcgac
     2461 caggtacttc gcccggatca gggtggcgag ctgcccgagg ttcatctccg ggatcaccac
     2521 cttgtcgtac ccccgcagca cctcgcccag attccgcggg aaggggttga ggtggcgcag
     2581 atgggcctgg gcgatgggct cgccggcccg gcgcagccgc cgtaccgccg ccgtgatcgg
     2641 cccgtacgtc gaaccccagc ccagcaccag cgtccgcgcg ccgtccgggt catcgacctc
     2701 caggtccgcg acctcgatgc cgtcgatctt ggcctgccgg gtgcggacca tgaagtcgtg
     2761 gttggccggg tcgtaggaga tgttgcccgt gccgtcctgc ttctcgatac cgccgatacg
     2821 gtgctccaga cccggcgtgc ccgggatcgc ccacggccgg gccagagtcc tgggatcccg
     2881 cttgtagggc cagaacacct cactgccatc ggccagcgtg tggttcgcac tggtggcgaa
     2941 ctgcacccgc aggtccggca gctcgtccag gtccgggatc cgccacggct ccgagccgtt
     3001 ggccagatac ccgtcggaga gcagcatcac cggtgtgcgg tacgccagcg cgatcctcgc
     3061 cgcctccagc gccgccccga aacagtccgc cggcgtgcgc ggcgcgacga tcggcaccgg
     3121 cgcctcaccg ttgcgcccga acatcgcctg cagcagatcc gcctgctcgg tcttggtcgg
     3181 cagacccgtc gacggccctc cccgctggat gtccaccacc agcagcggca gctccaggga
     3241 caccgccaga ccgatcgtct cgctcttcaa cgccaccccc ggacccgacg tcgtcgtcac
     3301 cgccagcgac ccgccgaacg ccgcacccaa agcggcaccg atccccgcga tctcgtcctc
     3361 cgcctggaac gtgcgcacac cgaagttctt gtgccgggac agctcatgca ggatgtcgga
     3421 cgccggcgtg atcgggtacg agcccaaaaa cagcggcaga tccgcctgcc gggaagcagt
     3481 gatcagaccg taagccaggg cgaggttgcc ggaaatattg cggtaggtac ccaccgggaa
     3541 cgccttcgcg gccggggcga cctcgaagga gaccgcgaag tcctccgtcg tctccccgaa
     3601 attccagccc gcacggaacg ccgcgatgtt cgccgccatg atctcaggct tcttcgcgaa
     3661 cttcgacctc aggaacctct ccgtgccctc agtgggccgg tggtacatcc acgacagcag
     3721 acccagcgcg aacatgttct tgctccgctc ggcctcctta cgggaaagat cgaactcctt
     3781 cagcgcctga accgtcagcg tggtcaacgg caccgggtgc aggctgtaac cgtccagcga
     3841 accgtcctga agcggggaag cggcatagcc caccttctgc agggcacgct tggtgaactc
     3901 gtccgtgttc acgatgatct ccgcaccccg cggcagatca cccacgttcg ccttcaacgc
     3961 ggccgggttc atcgcgacca gcacattcgg cgcatccccc ggagtgagga tgtcatgatc
     4021 ggcgaaatga agctggaagc tggagacgcc gggcagagtg cccgcgggcg cgcggatctc
     4081 agcggggaag ttcggaagag tggaaaggtc gttaccgaag gacgcagtct ccgaggtgaa
     4141 ccggtcaccg gtgagctgca taccgtcacc cgagtccccc gcgaaccgga tgatcacccg
     4201 gtccagacgc cgcacatcct tnnnnnnnnn nnnnnnnnnn nnnnnnctcc tgcggagcgg
     4261 atcgagcgct cacttccccc accttccgaa gtaacggaca gacatgaaca gggaagatat
     4321 tgtccgccgc gcccattccg ccaacccggc tgtgcaactg cggaaatcgc tgctccgtgt
     4381 gcctcgccac gcacttgaaa acggcggatt gtcacccgat catgaatcac ttcaggattc
     4441 cgggccgttg tccgatgctc gcgcgcgcag aaacctcctc aggttttccc gacgtcacag
     4501 gcgggccgtg tgccccgccc ttcgcaccct cgccgagccg tggtccggcc gatccgacga
     4561 ccaggtagat ccttgcagcg aaggtgagtt cgcatgtctt ctctcgacat cacgggcgtg
     4621 cccacggcgg cccccgtcga tcttcggtgg tccaccgctt ccggggtgga ggtgagactg
     4681 acggcctgcc atgccggcag cgcccaggcc gtgcgcgcca ggctggagac ggcactcgac
     4741 gagcgacgcg gaatgctgct gttccgcggc catgaccggg tgctcggcta tgtcgacccg
     4801 ccactcgaac tgtcggtcga gtcgaccgag ttgacggtcc gggcgctcaa cgaccggggc
     4861 cgggtgctga tccccgcgct gcggacggtg ctcgccggac acctgctcct ggagccgggc
     4921 acgaacgaca cgctgcgtgg ccgggcccgt cccacgagcg gcgtcttcgc cgaggaggac
     4981 cgcacccgca acgcgggggt gttcggcgca gtccgcgccg tactgcgcgg cctgtcggcg
     5041 tccgaggact cgctgctggg cctgtacggc gccttcggat acgacctgat cttccaggtg
     5101 gacccggtcg agcggcacca ggaacggcgc acgggggacc gcgacctggt cctgcatctg
     5161 cccgacgaaa tatgggagtt ggacctgcgg caggacctgg cggtgcgtca ccgctacgac
     5221 ttcacgttcg caggcgcgga caccgggggg ctgccgcgca cctcgcccgt gcagccgttc
     5281 gtcccgggtg cgcccctggc ggcgcgcgac cacgctcccg gcgagtacgc gcaggtggtc
     5341 gccaaagcca tgccgctgtt ccggtcgggc gacctgttcg aggtggtgcc gagccaggtc
     5401 ttccgccggc cctgccccac cccgccgtcc gacgtcttcc gccggctgcg gctgcgcaac
     5461 cccgcgccgc acagcctgct gatgaacctc ggggagcggg agtacctggt gggcgcctcc
     5521 ccggagatgt tcgtgcgggt gcggcacgaa ccgggcgccg agggcaatcg ctcggtgatc
     5581 gagtcgtccc cgatcagcgg caccatcgca cgcgggcagg acgcgctgga ggatgcgcgg
     5641 cgcatccgcg aactgctcgg ctcggtgaag gaggagtcgg agctgaccat gtgcaccgac
     5701 gtggaccgca acgacaaggc ccgggtctgc gagccggggt ccgtcgaggt ggtggaccgc
     5761 cggcgcatcg agatgtactc ggcgctcatc cacaccgtgg accgcgtccg cggtgtgctg
     5821 cggcgcgaca gggacgccct ggacggcttc ctcgcgcatc tgtgggcggt caccgtcacc
     5881 ggcgcgccga agctcgcggc ggtggacttc atcgaacacg cggagcgttc gccgcgccgc
     5941 tggtacggcg gcgcggtcgg gcggctgggc ttcgacggca ccctcgacac ggtgctgacc
     6001 ctgcggacgg tgcacatcct ggacggggtc gccgcggtgc gggcgggtgc gacgctgctc
     6061 cacgactcct cgccggaagc ggaggaggcg gagaccgagc tgaaggcgcg ggccctgctg
     6121 gaggtcctgg acgaacccgc cgtacggccc gcgcccgtga cgcgggtccg ggcgcgcggt
     6181 gtgggcgcgg gggtgcgcgt gctgatggtg gaccaccgcg actccttcgc gcactgcctc
     6241 gccgaccatc tgcggcagac cgccgcggag gtcaccacct tccgcagcgg cagccatctg
     6301 cccgtgctgc gcgaacagcg accggatctg ctggtgctct cccccggccc cgggcgtccc
     6361 gaggacttcg gcatggcccg cacgctggcc gaggccgagc ggctgggtgt cgcggtgttc
     6421 ggagtgtgcc tgggcctgca gggaatgatc gagtactgcg gcggcaccct ggacgtgctg
     6481 gggcgaccgg tgcacggcaa gccgtcggcc gtacgggtca ccgaccccgg gtcccggctg
     6541 ctggccgggc ttcccgaaca gttcgaggtg ggccgctatc actcgctgta cgccccggtc
     6601 gactcggtgc ccgcggagct gcgggtgacc gctgccacgg aggacggggt gacgatggcc
     6661 gtggagcacc gtgaacggcc atgggcggcc gtgcagttcc atccggagtc catcatgagc
     6721 gcccgaggcg cggcggggcg gcggatcgtg gacaacgcgg tgtcgtcgct gaccgccgcg
     6781 acgctccggc agaccggcgc cgcccgtccg tgaccggacc cgcccgcacg acactcggcc
     6841 ccgccggcat gtgcccggcg gggccgagtg tcgtgcaacc cgtacgccga agggcccgtc
     6901 gggattcctc ccggcgggcc ctggtccgcg cctgtgtcgg gcgggtcttc ggcttgtcag
     6961 gcgtggttca tgtcccgacc gtgaccacct ccggttcccc ggcctcggtg gtggtctcgg
     7021 cgaggcgcag tgcctcctcg atgagggttt ccacgatttt cgactcgggg acggtcttga
     7081 cgacctcgcc gcggacgaag atctggccct tgccgttgcc ggaggccacc cccaggtcgg
     7141 cctcccgggc ctcccccggt ccgttgacca cgcagcccat gacggcgacg cgcagcggtg
     7201 cctgaaggcc ctccaggccg gcgctgacct cggcggccag cttgtagacg tcgacctggg
     7261 cgcggccgca ggaggggcag gagacgatgt cgagcttgcg gggccgcagc ccgagcgctt
     7321 gcaggatctg ggtgccggcc ttgacctcct cggcgggcgg cgccgacagg gacacccgga
     7381 tggtgtcccc gatgccctgc cggagcaacg ccccgaaggc caccgcggac ttcacgatgc
     7441 cctggaaggc cgggccggcc tcggtgacgc cgaggtgcag ggggtagtcg caccgctcgg
     7501 cgagcagctc atacgcacgc accatgacca gcgggtcgtt gtgcttgacg gagatcttca
     7561 ggtcgtggaa ttcgtgctcg gcgaacaggc tcgcctccca cagcgcggac tcgaccagcg
     7621 cttcgggtgt cgccctgccg tgcttggcga gcaggcgccg gtcgagggaa ccggcgttga
     7681 cgccgatgcg gatgggggtg ccgtgctcct tggcggcgcg ggcgatgtcc ttgatccggt
     7741 cgtcgaactt cttgatgttg ccggggttga cccggaccgc ggcgcagccc gcctcgatgg
     7801 cggcgaacac gtagcggggc tggaagtgaa tgtcggcgac gacggggatc tgcgccttgc
     7861 gggcgatctg cggcagggcg tcggcgtcgt cctgggacgg gcacgccacc cgcacgatgt
     7921 cgcagccggc cgcggtcagc tgggcgatct gctggagggt cgcgttcacg tcggccgtcg
     7981 gggtcgtcgt catggactgc acggagaccg gtgagccgct gcccacgccg accttgccga
     8041 cccggagttg gcgggtcggg cggcgtgggg cgaggggttc cggcagtgtc cggggtgtct
     8101 ggggcatgcc gagggagacc gtcatgattc cttcttctgg tcaacgggcg ggacggcggg
     8161 tcagtgagcc gggtggccgg cggcgggtgc gggccggccc tgccgcggta cggcgtcgag
     8221 ggcggccagt tcctcggcga gcgtgcgggc gatgtgccgg ctcgtcaggc cgctgccggc
     8281 gagcacgtcc ccgcgggcgc cgtggtcggg gaagtcctgg gcgatgccga aggtgcgtac
     8341 cgcggcggtg gcgccgtggt cgcagagggc ctgggcgacg gcggcgccca caccgccgac
     8401 ccgcccgttg tcctccacgg tcgcgaccat ccggtgttcg cggcctagtt ccagcaggcc
     8461 cgacggcacc ggcttgaccc agcgcgggtc gacgacggtg acgccgaagc cgtgtcccgc
     8521 gagcaggtcg gcggtctcca ggcaggtggt ggccatggtg ccgacggcga ccagcaggac
     8581 gtccgggtgc tcggcccggc gcaggatgtc gacaccgccg caggagtcga gggcggggat
     8641 gtcctcgccg acgctgccct tggggaaccg tacgacggtg ggggcgtcgt cgacggcgac
     8701 ggcctcgcgc agcgcccgtc gcagggtggc tccgtcgcgt ggggcggcca cgcggaggcc
     8761 ggggacgagc tgcagcagcg acaggtccca catgccgttg tgcgacggcc cgtcgtcgcc
     8821 ggtggcgcct gcccggtcga ggacgaaggt cacgggcgcc cggtgcaggg cgacgtccat
     8881 caggacctgg tcgaaggccc ggttgaggaa ggtggcgtag agggcgacga cggggtgcag
     8941 tccaccgagg gcgagcccgg ctgccgaggt caccgcgtgc tgttcggcga tgcccacgtc
     9001 gaaggtgcgc tccggatggc gctcggcgaa ccggctcagc ccggtcgggg cgagcatggc
     9061 ggcggtgatc gccaccaggt ccggccgctc ggcgcccagt tcggccagct cggcaccgaa
     9121 cacgtcggtc caggagggcc gttcgcggcg ggccggagcc gctgcggccg gctgggcacg
     9181 cacggcgtgg aaacggtctg cctcgtcctg ttcggcaggc cggtggccgc ggcccttctc
     9241 ggtgaggcag tgcaccacca ccggccggcc gagccgcttg gcgcgggtca gggccgactc
     9301 cagggcctcg atgtcatggc cgtcgaccgg gccgagatag gccaggccca gttcctcgaa
     9361 gagaccccgc gggccgaggt ggccggcatc ggcgcggggg ccggtgcgca aggctgccag
     9421 atggtcggcg aggccgccga cggtgggggc gtaggagcgt ccgttgtcgt tgacgacgac
     9481 gaccaggggg cggtgcttcg cggcggcgat gttgttcagc gcttcccagg ccatgccgcc
     9541 ggtgagggcc ccgtcgccga tgacggcgac gacgctgcgg tcggtgctcc cctggatctc
     9601 gtacgccttc gccaagccgt ccgcgtagga gagcgcggta gaggcgtggc tgttctcgat
     9661 gacgtcgtgg gcggactcgg cgcggcaggg gtatccggac aggccgccgc ggcggcggag
     9721 cgtgtcgaat ccggcggccc ggccggtcag gatcttgtgc acgtaggtct ggtgaccggt
     9781 gtcccacagg atgcggtcgc gcggtgagtc gaagacccgg tgcagggcga tggtgagttc
     9841 caccaccccg aggttggggc ccaggtgacc gccggtcctg gtgaccttct ccaccaggaa
     9901 ccggcggatc atcgcggcca gttcggtcac ctcggccccg gacagcgcgc gcaggtccgc
     9961 cggcccggtg atctcgtcaa gctgtggcaa gacgcctcct tcgtcgtgtc gtcgcgtacc
    10021 gcgcgggtcc acggcgcgtg ggtgtgtcag tggtcccggt aggcgacccg gtgtgccatc
    10081 tcggtgagtt cgcctcgcca gtcctcgtcg atgggtgcct ggtgcagcac gtcgacggcg
    10141 gtggtgacga ggtggtcgat ccgttcctcg acctcggccc ggacgccact gtcggtcagc
    10201 aggcggcgca gttcgtcggc gtcggccgcg tggatcccgc cgtccgcggg cagcaccagg
    10261 gcccggaccc gcgcgtcgcg ccggacggcg agggcgagca gcagggtcat cttgtgctgg
    10321 gcgaagtcca gtccggccgg tttgccggtg atctcgccgt cgccgaacgc gtcgatgagg
    10381 tcgtcgcgca gctggaaggc ctcgcccaga gcccgtccgt acgcctcgaa cgatgcggcg
    10441 aggtccgggc ggcctgcgag cagggcgccg atggtcagcg gccggtggat ggagtagtgc
    10501 ccggacttgc agacggcgat ccggcgggac gtctccgggt cggggtcgta ggcggccgcg
    10561 accgagacgt ccaggaactg tccgaccagc atctcggact tcagccggga ccattcgtcg
    10621 aggacgggcc gggagaatcc ggcaaggagc tggtccgcgt aggtcagggc gaggtcgccg
    10681 gcgaggatcg ccgcgttctc accgtaccgt tcggagcttc cccgccagcc cgcccggcgg
    10741 tgctcagcgg cgcgggcgac atggagggtg ggcaggccgc ggcgccggtc ggactcgtcg
    10801 aggacgtcgt cgtggatgag cgcggacacg tgcagcagct ccagggccgc gccgaggcga
    10861 gccgcggcgg ggtcgtcggg gctgccgccc gcgagcagga aaccggaggc gcagaacgcg
    10921 ggccgcaacc gcttgccgcc ggccgccacg aggtcgccga tcgcgtcgag gaggaccagc
    10981 gcctgcgggg cgtcgtcggc ccagcgggcg cgctcctcgg cgagcagggc ggcgacggcg
    11041 cgttcgacgc cgtccaggat cgtggcgcgc gcctctttga gagcgcgggc ggcgggcgcg
    11101 gaacacgtgg ttgtcgtcat ggcttctcct cggccagggg cgtgctgggg acgcggtcgc
    11161 cggcggtggt cgccagccgt gcgggcaggg cgaagaccac gtcctcgctg gcgccccggt
    11221 cagtctcgac gccggtgtag cccagttcgg tgagccgctc ggcgagcccg cggaccagga
    11281 tctcgggggc gctggcgccg gaactgatgc cgacggtggt gacagactcc agccagctct
    11341 cgtccaggaa ggtgacgtcg ggcaccaggt gggcgcgagc gccgtgttcc cgggcgacct
    11401 ccaccatccg cacggagttg ctggagttga cggagcccac gacgaggacg aggtcgctgc
    11461 ggcgggcgag ggccttcacc gcgttctggc ggttctggct ggcgtagcag atgtcgtcgc
    11521 cgtgcgggcc cacgaggtcg gtgaacctgc ggcgcagcgc gtcgacgacg cgtgcggtct
    11581 cgtccagcga cagggtcgtc tgggtcaggt aggccacggg ggcgtcgtcg ggcaggtcga
    11641 gccgttcgac gtcctcttcg gtcccgacga ccagggtgcg ttcgggtgcc tcgccgcggg
    11701 tgccctcgac ctcctcgtgg tcggcgtggc cgacgagcag gatggtgcgg ccgtcgcggg
    11761 cgtagcgcac ggcctcctgg tgcaccttgg ccaccagcgg gcaggtcgcg tcgatgacgt
    11821 cgagtcggcg ctcggccgcg gcgcggcgta cggccgggga gacgccgtgg gcggagaaga
    11881 cgcagaccgc gccctccggc acctcgctct cgctgtcgac gaaccgggcg ccgcgttcgg
    11941 tgagttcggc gaccacgtgg tggttgtgca caatctcctt gcgtacgtag acgggcggtc
    12001 cgtacaggtc cagggcccgc tccacgatgc cgacggcccg tcgtaccccg gcgcagaagc
    12061 ctctcggctc ggccagcacg atccgccggg tgccggagtc ttcgtcgggt gctgtctgcg
    12121 tttgctggga tcccacgggt ttcttccttc caacaggctt gccgggggcg ggtacgggcg
    12181 ggccacacag gggccggccg gaatgcgctg tgcccgggaa cgtctcgccg ggcggctggg
    12241 cgggcaggtc cgccgggcgg ccgcgcaaag gacgccgagg taccggccgc acggtgcgcg
    12301 gccggtacct cgtcaggctg cagtcccggc ccccggacct gacacgtccc gtccgggcgg
    12361 ggcatcgact ccggagggaa cgcgggggtg ccgggacttc gcggctgaag aataggccga
    12421 acggcccggc gggcccacgg tgttcagctt cggcaaccct tcgccacctg tcgtacaccg
    12481 tgcaactgcc gggaattcac acttgctcag tcgctccggc agacaaaagc gatcttcctc
    12541 gtattctttc gggaccccgg cgccgagtcc gctgcgtggg gctccggcca ggacgtgagt
    12601 cgaaccgtcc gccggaacgc tcacttccga tttttgaggt cacttccatg aactctcacc
    12661 gtcgtccgcc cgccctgcgt cgcgtcctgc tctgcgcggc cctggcctcc gccacgctgc
    12721 tggccggccc ggtcggcgcc gtctgcctgc ccaccgcccc ggtcgccgtg gcgcgcgccc
    12781 aggactccgc cgtcacggtc gcgggcgtgc tcaacttccg tgacgcgggc ggctatccga
    12841 ccgccttcgg gcctcggatg cgcaccggtg tgctgtaccg ctcgggcgca ctgcagaacg
    12901 ccacggacgc gggtgtgcag acgctgtcgg acctgcacgt cacgaaggtc gtcgacttcc
    12961 gcacggacgc ggagcggacc gccgccccgg accggctccc ggccggcgcg tcggccgctc
    13021 tgtacccggt gtcgtccacc gaccggctcc agtccttcgg ccagctgctg tcgatgacgg
    13081 cggacgagca gcaggccctg ctgggcgacg gcggggccga ggagatgatg ctgcagaccg
    13141 cgcgggagtt cgtgacggtg cccggcaagc gggagcagtt cggcaaggcg ctgcgcgaca
    13201 tcgccgacgc ccggggcgac gacgccgtcc tggtgcactg caccggcggc cgggaccgca
    13261 ccggctggct gatcgcgatc gtacagacac tgctgggcgt ctcccgtgac gacgtgttcg
    13321 cggactacct gcgctccaac accgaactgg cttcctggaa gcagggcgtg ctgcagcagc
    13381 tcgccgccgg cggtatgcag gatccgggtc tggtcgagcc cctcctcgat gtcgacgcct
    13441 cctatctgca ggcgtcgttc gaccaggcgc agcagtcgta cggctccttc gacgcgttcg
    13501 tgcgcgacgg tctcggcatc gacgacggga ccctggcgcg actgcgcgca cggctgctct
    13561 gaccgcggcg gattcgccac aggggtgcgg ctgagccccc gcgggaagcc ggacaggaaa
    13621 gtgccctgcc ccccggggga tgtaggggca gggcacggcc ggtaagcggc ggttactgct
    13681 cgtggatctc cacgacaccg ctgctgccgt cgacggtgac gagcatgccg tcccgaagga
    13741 tctgggtggc gttgccggtg gccagcgcgg ccgggatgcc gtactcgcgg gcgatgatcg
    13801 ccgcgtgcga cagcgcgccg cccgtgtcgg tcaccaaggc gccgatgctc gggaagacca
    13861 ccgaccacac cggcgaggtg atcgggcaga ccaggacgtc accggcccgg atcttgtcga
    13921 actcgccctc gctgagcacc acacgggcca caccggtgta gcgtccggcc gatccgggca
    13981 ccccgcgcag ccggccgctc tctccctggc ggggcgcggg tgagacgccg cccatgtgct
    14041 gcatcgtcca ggcgaagccg cccatcgtct cgcggacctc ggccggcagg gcgtccatcg
    14101 acggcggcgg gccgggccgc tcgccgaagc tgtccgcgcc ggggttctgc agcgcccacc
    14161 ggtgctcgcc gcgccgccgc gtgacggtct cgcggacgtc ccgggactcc agcagggcct
    14221 ggcggagttc ctcgacctcc aggaagaacg catggtcggc gcggtccagc agaccgcgcc
    14281 cggcgagccg gccggccgcc tccagggcgg cccagcgcag cagggcgttg ggcgcgctga
    14341 cggtccagta ctcgttgtcc tcgcggaccg ggtaggcgcg ttccgctccg gcgagcagtg
    14401 cgccgaagcg ctcggcctcg gcgccgccgg cgagttcggc gtgtgccttg gccaccgcct
    14461 cccggcgggc ctgctccacc gcgccgccgc tgtggtcgag ggcggcgtcc tggccgagct
    14521 ggtcgcgcag cagggagagg atcagttcgg gccgctccgc cagggcgggg ttggccagtt
    14581 cgtactggag agcgcggcag ccgtactcgc cacggtacgt ctcgaaggcg gcggcgaact
    14641 cctggtccgt ctccagcagg gtgcgcaggg cggccaggtc gggggtcccc tgcagccgct
    14701 gccgggccgt acgggccagc tcggacatgg cgagcgcggg gccggtgctc tcggtggaca
    14761 ggccggtcag cagctcgaag acgcggccct gttcccagcc cagcgtgccc gtcgtgaaca
    14821 ggccgaaccg gcccagcgcg atggacaccg cgcccagcag ccggaagtgc acctcggtgc
    14881 cgtcccggtg cagcgcgcgg acctgggcga ggtgctcggc gagcgcctcg tcggacaggg
    14941 cggtcacatc gacgcggcgc agtgcgtcga tgcggtcggc gaagcgcggc ctgatctcct
    15001 ccagccattc ctcgatcacc tggcctgcca ggtcctcgcg gacggcggcc acgcaggtgg
    15061 cgatgcgggc gggggcgtcg gccggactca gcggcagggt ggccatgtag cgccagccgc
    15121 cgatggtggc gaaggccagt cccttgagca ggaggccgaa ctgggcgcag acgccttcga
    15181 ggacggtgtt gttgtagtcc agcagctccc gggtcatcgg cagcagcggc agcggcgcgt
    15241 gcgtggtgtc cttggcccag aagccccgcg gggcgttgac gggcacgggc accggttccg
    15301 gctcggggtc ggcgatcgcg gtgatgggcc ggccctgaag gaggtggaga cggccggcgg
    15361 cgcgcgccca ctcgatgtcg gtcgggccgc ccaggacctc ggcgacccgc tcggccagcg
    15421 tggcgatctc ctgcgcctgt ccggcggtca gggcgccgtg ccggccggcg gtgttcaccg
    15481 gggtgccggt gccgcccgcg gggacggccc agtcgtccgg ggacacctca ccggacacca
    15541 gctgttcgcc gatgccgcgg accgcgctga cgaggacctc gtcgcgggcg ccggtgaccg
    15601 ggttgacggt gaaggccacc cccgcggtct ccgcgggcac cagccgctgc accaggacgg
    15661 cgagcggagc gtcgccctcg gcgccggcgg cggtgcggta gccgcggacc acctcggtga
    15721 agccggacgc ccagcacgcg cggaccgcct cgtcgagagc ctccgctccc tcgacgtcga
    15781 ggatcgtcgt gtactgcccg gcgtgcgagg catgcgcccc gtcctcgtcg atgccggagg
    15841 agcggaccgc gagggggccg tcgagacggc gtgccacctc ctggaccgcg gcgcggatac
    15901 cggcgtcgag cgggctcccg gcgaccgtct cggccgtcac ctccgccagt tcacgcacat
    15961 gacggaccat ggcccgggca gtgacgacgt atccgtcggg tacgggaaag cccgatcgcc
    16021 gcagctgcgc cagtactgcg gccttcgcgc cgacctcggc gcggtccagg gcccgggggt
    16081 cgtccagtga caccacgagc ggtgccgcgt ctgtgttgtc gttcctgtcg ttgctcactc
    16141 ggctctcctc gcgaggacgt gatgtggttc ttccgccccc tgccgggtgc gcccgggcag
    16201 cgggctggtg gtgggccggc gcgggcacgg gcggtgcccg acgggccggg ggcggcgggc
    16261 cggaccgccg acggtttcgg ggcgcgtgcc gcagcgtaca aaacggaccg gtcggccgaa
    16321 aaattgttca acttgcacac ccggacgggc tgttcacccg cccggcggcc cggccgcgcc
    16381 ccgcagacgg tccgttttgt ccgcacgagc ggtccgtttc tacgctccgg ccgcctgtcc
    16441 gttcagccgg cggcgagggt cggcgcgggg tgcgccgtga cctcacggct gatctcgacc
    16501 agtgcctgtg ccgtctcggc gggccgctcc aggacgtaca tgtggccgcc ctcgaccagc
    16561 cgggtcgacc ggggtgtgag gacgtcgccg agccgggcca gggcggcggg cgggcacgcc
    16621 acgtcgtcgg tgccgccgag cagatgcagc ggggtgtcga gcggttcggg cgcccatccc
    16681 cgtcggtcca gcagcgccag gtcctggcgc aggttgggga cgaggaaccg cagcgcgaag
    16741 tcctcggacg tgttcaggtc gggcagcatg ccctgtcggg tggcctcccg gaaaagcgcc
    16801 cggtcgtcca gctccagcag tccggccggg gagtggtgcg gccggggcgg tgcggagagc
    16861 accaggtgca ggctctcgga gggcggcgcg gcccgcagcc aggccatccg gtgggccacc
    16921 gcggcaccca ggctgtgccc gagcaccagg gccggttcgc gcaggtccgc ggcgagcagg
    16981 ccgaggtaga aggaggccag agcgtcgagg ccggcgggtc cgggggcgaa tccggtcggc
    17041 ggctgtacgg cggtgacccg ccagtcgcgc gggatgtgcc gggccagccg gacgaaggag
    17101 cgggcggatc cgcccgcgaa gggcaggcag accaggtgga agccccggcc ctcctgcagg
    17161 acgacccgtt cgggaccggc tctcatgtct gtccttccat ctcgcgccga cggatgagga
    17221 atcgggccgt cttcccggtg gacgtcgtgg gcagggcgtc ggtcagacgg acggtgtggg
    17281 ggcgtttgaa gggcggcagg gtgcggcgca gcgcggccag cacctgtccg cgcagttcct
    17341 cgccgacgcc gtcctcgggc accacatggg ccacgatccg gacgacgtcg tcctggtcgg
    17401 gtacgccgac cacggcgcag gagccgacgc cggggacggc gaggaccgcg tcctccacct
    17461 cggaggggag gatcttcatc ccgccgacgt tgaggatgtt gtcggagcgg ccgaggtaga
    17521 cccagccgtg ctcggggtcg tgggtcatgg tgtcgccggt gtgcacccag ccgtcccgga
    17581 aggtctcggc actcaggtcg gggcggttcc agtagcggtc ggcgacgctg gggccgcgca
    17641 cccgcagatg accgatgccg ccctgttcca gcgggcggcc ctcgtcgtcg cagacctcgg
    17701 cctcgaagcc gggcaccggg atgccggtgc tgcctgccgg agagaccccg ggcacggtgg
    17761 ccaggaagat gtgcaggcac tcggtggagc cgagaccgtt gacgacagtg aggccgaggg
    17821 tctcggtcag ccgagtgctg agctgggggc cgaggtgctc ccccgccgac acggcgagtc
    17881 gtacggagga caggtccagc cgccgggcgg cgtcgggcat ggacagcagg gccgcgtaca
    17941 gcgtcggcac ggcgaacagc agggtgggcc gggtacgggc gaccagacct gccacggcgt
    18001 gcggttcgaa gcggccggcg aagagcacgg cactcgcgcc gaccgagaag ggcagcagga
    18061 gcgagtttcc gaacccgtag ccgaacggca gcttcgccgt ggacagcacc cggtcctcgc
    18121 tggtgatccc gaggtgccgg ccgaaggtcc gggggaaggc cagcagaccc cggtgcaggt
    18181 gcaccacgcc cttggggcgc ccggtgctgc cggaggtgta ctggatcagt gcggggtccc
    18241 gcccgtcccg ggcgcgcacc gtccacagcg gggtcgctcc ggtggtggcc tccgcgagag
    18301 aggtgaccgg cccggcgccc ggccccgcgc tccacacgcg cacgtccggc gcgtgttcgg
    18361 tcagctcccg ggccagctcg ccctcggcgt cctgtacgac gacggcgcga gggccgcagt
    18421 cggccacgac ttcgcgctgg tcgtcgagcg gcagcatcgg gctgaccggt acgggcacgg
    18481 cgccgagccg catcgcggcc agcacgcacg ccaccgcgtc gacgccgtcc ggcagcacgg
    18541 tcaccacgcg gtcgcccggc gcgatgcggg cctctgcgag gacgcgggcc gtgcggcaca
    18601 cccgttcgtg cagcctgctg taggtcagct ccccttcctt ggtgaccagg ctgacccggt
    18661 cgccgttgcc cgcgctcaga tggcggtcca ggtaccacca gccggcgttc gtcgccgtct
    18721 cgggcccgtt cacgcggcct ccccggggtg cggggcgggc gggccgacga ggacggcggt
    18781 ggcgctgccg ccgcggtcga cgcccaggca cagggccagc ggtccgatcg gggcggcggg
    18841 cgcgtcgccc cggtccggag ccgcgggcac gacgcctcgg gcgagtgcct cgacggccac
    18901 gaccacggcc accgccccat cggcgccacc gcagtgtccg gtggccgcca gggggtcgca
    18961 caccggcagc ttggggccga acacggtgtc cagggccatg cgcacggctg tcccggcgac
    19021 ggcgtcgccg ccggtgacgg tgacggcgca gcccacctcg gccgcgaacc ggtccgccgt
    19081 gcgcagcgcg tcgaggaccg cctcttcggc cgcccgggcc agggcgcggg acgcgtccgg
    19141 gtcggtgtcg gcgggttcgg cggtgacctg gcaggtgccc agcatccggg cgaggtgggg
    19201 ctcggtggcg ccnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19981 nnnnnnnnnn nnnnnnnnnn ggactgcggg ccccacaccg ggttgaccgg tccgccggcg
    20041 ccctgggagg cgttgtggat ggcgaggtac tcgttgcggc cggcgtgcag ggtgcccagg
    20101 acgacgccgg tccggtcggg gtccacggcc tcgcggacgc cggcggcgtg cgcggcgtac
    20161 agcagcagcc gggcgtcgcg gctcatggcg cgggcagcgc gggcgccggc cacgtcggtg
    20221 aggtcgagcg gggtgcggac gtggcccgcg aagacctccg ggtcggtgtc gtccgccgtg
    20281 gcccgctccg ggtgggcggc gggcagtggg ttggcgacga gcgggactcc ctgggtggtg
    20341 aagggccgcc ggccgtccag caggtcctcg aagagccggg cgaccgaggt gccgcaggcg
    20401 gtcaccgctc cggcagcggt gatcacggcg cccgtcgagg gcggtgacgg attcggtgta
    20461 cgcacatcaa tccttcaggc agtgagggcg gttgacgagg ggcgcccggc ccgtcggggt
    20521 ggggcgcgtc ggcgggcgtg cgggcggctc agtccgggta gcgcgccagc acgatcgccg
    20581 aggtgttccc gccgaagccg aacgcgttgc tgagggtcac ccgcacgggc atgtcgcggg
    20641 cgggtccgcg caccacgtcc aggccggcgc agctctcgtc cgcctcccgc agggtggggt
    20701 tgccggggac gcggccgtcg cggatggcga ggacacacgc gatggcctcc acggcgctcg
    20761 cgccgccctg ggagtggccc atcaggccct tgatggagga gaccgcgggc gtgccgcccc
    20821 ggctgccgaa gtactcggcc aggcaggccg cttccaggga gtcgttggcc ggggtgccgg
    20881 tcccgtgcgc gctgacgtag tccacctcgc gcgggtcgat gccggcctgt tcgaggctgt
    20941 cctgcatgca ccgcagcatg ccgagaccct gcgggtgagg ggccgtcatg tggtgggcgt
    21001 cggcggcgag cgcgtagccc ggcagttcgg ccaggacggt ggcgccgcgc cgcaccgcgt
    21061 gctccaggga ctccagcacc aggacgccgg cgccttcgga gggcatcatg ccgcgccggt
    21121 cccggtcgaa ggggcgtacg gcgtcggggg ccagcgcgcg cagggtggtg aacagccggt
    21181 acacggattc cgacagttcg tccacgccgc cggcgaccat ggcgtcggcc tgtccggagc
    21241 ggatggcgtc ggcggccatc gcgagggcgg tgttgcccgc ggcgcagccg gccgcgacca
    21301 cctgccgggg cccgcgcagt ccgaaggcac gaccgggttc ccgggccagc gactgcggtg
    21361 agtcccagga gaagtcctcg gtgagcgggc ggccctggcg gcgcagttcc tccagatgcg
    21421 ggcgggtgcc catgacggtg ccgaccacga tgccggtgcg tgccagaccc gggtggccga
    21481 gcagtccggc gtctcgcaac gcggcgtcga cggagtggtg gacgtagcgc agggagcgcg
    21541 ggacgctgcg gccgtccgag gtcagcgggg cggtcagggc ggggtcggtg acctcggcgg
    21601 ccaagtgggt ggggtatccg tcggtgggga accgggtgac gggtgcggtc gcgacggttc
    21661 cagccgtgac gttgcgccag aactcctcga cctcggtgcc gagcggggtg gccagcccca
    21721 ggcccgtcac gacaacccgg tggcggcccc tcgtgtcacg cgacatgccg ggcgacctga
    21781 cggcagaggt cctcgacggt gtcgctgacg gcgacctgct cgtgggtgag cgagcagttg
    21841 aaccgggact cgatgtgggc gacgatctcc agcttctgca gcgagtcgcc gccgaggtcg
    21901 tcatagaaac gagcctgagg gggcacctgt tcggtcggca gggtcagtac gccggcgacg
    21961 acgtcggtga ccacggcgcg gatctcggtc tcgttcatga gtgctccttg acggtgaggg
    22021 cggggccgaa caagcggacc cagcggcgca gatgagacag ggtcaggccg cctgaccagt
    22081 gcagggtttt ggaggccacg agccagtagg cgatccccgc ggcggcggcc gcggcggcgg
    22141 cccgggtcgg ggcgcaggcc gtcaggcaca gcgcgaggaa gtagaaggtg tactggtgca
    22201 tcacctcgcg ggccgcctca cggtccagcg gggcgaccgc ccgggacgcg gcggtgacca
    22261 cgagcgccga caccgccacg agcggcagca gcgcaagggc cggcagcggc aggacgtgca
    22321 gcgccgcgta cagcgccagc agcaggaacg gtgcgccgat gaaggcgtac acggcggcgc
    22381 cccgtccgat ccgggccacc gagagccaca ggctggagta gcccaggcga cggtcgccct
    22441 cgacgtcggt gatgtccttg atgccggaca gaccgaggct gaaggcggcc agcacggaca
    22501 cggccggcag taccggggac agcagggtgt catatccgcc gtacaccgcc cagccggtca
    22561 gcaggggcgt gatcagcggt gcggtcaggg cgagcagggc aaggacgcgg tggcgcttga
    22621 aggcggggcc gatcgagtag ccgatggcca cgccgatgtc gaccagcagc agggcgggca
    22681 gggcgaagcc ggggtgccgc caggtgaggg ccgcgccgat gaggacgaac accgtccagg
    22741 acagcacggc caccgcagtg agccgggacc agccgaactc ctcgcacagc cgggtgcgtt
    22801 cgggccggtt gacctcgtcg gccgcccggt cggcgatccg gttgaccgac tcggtgccca
    22861 cgcagtaggc gagccacatc ggcacgccca gcagggccag gccgggaccc aggtgcccgg
    22921 tggccgcgag tccggcggcg aagcccaccc agtagtaggc ggtgaagcgg acgctgcagc
    22981 tgcgcagcag aagcagcacc gcacggcggg cggtcggcgg tcgcacccgg tgggccgggg
    23041 ccgtcagggg ggcggtcatg tcagctcacc cgctttcgca ccacgaccgg aaggcgggcc
    23101 gggccgcgca ggcccatgcc gggcttgtag gcgatcggct cctcggccag ggcgagcgag
    23161 gtgatgcgca cggtcagccc gcgcagtgcc tccttggcca tcatcgtggc cagcggggcg
    23221 cccaggcagt agtgaatgcc ccggccgaag gacaggtggt tgcggccttc acgcccgatg
    23281 tcgacggcgt cgggggcggg gaaggcccgc tcgtcacggt tggcggaggc gaccagcagg
    23341 atcaccgcgt cgcccggctc gatgacctcg ccgtgcagtt ccatccgctc cagggcgatc
    23401 cggccgacct ggtgggccgg gggctccagc cgcaggatct cctcgagtgt ggcgtcggtc
    23461 gtctccggcc gctcggcgat ccgggtgaag gcctcgggct gccgggcgaa gacgacggcg
    23521 gcgttgccca gcaggttgga gaacgtctcc tgtgcggcga cgaccagcag gacgcaggtg
    23581 gccgcgatct cctgggtggt gagcgcgctg ccctggtcgc gggcgcgcac cagctgggag
    23641 acgaggtcct cgccgtcgcc gccggcccgc cgggcggcga gttcgaggaa gtaggaggtg
    23701 caggcggcga ccgcggtgcg gcgggcctcg gcgacctcgg ggggcagggc gacgtccagg
    23761 tccagcagac ccgcgatctc ggtcgaccag gtggtgaact gcgcctggtc ctcggccggg
    23821 atgcccagca tggtgccgag gacgcggatc ggcatcgggg tggccagccg ctccatgagg
    23881 tcgaagcgct cggggagttc acccaggagt tcctccacga tcgcggtgac cgcggaccgc
    23941 aggttcctga tcatggccgg ggtgaaggcc tggccgacca gaccgcgcag ccgggtgtgc
    24001 tccggcgggt cggtcagcat gaacagcttg gcgtcccagt cgtccaggcc gaggcccagg
    24061 aagggcggcg gctcgtcgcc ggcctcgccc atgatctgct ggaagaactt ggagttggcg
    24121 aagtccttcc ccatccgtcg gtcccgcagg agcagttcgc agtcctcgta gcgactgacc
    24181 aggaaggcgc cgagcggccc gcgcagcacc gggaaacggt cgcgcagaac gcggtaggcg
    24241 ggaaacggat cggcctggaa agagggatcg gcgggattga agggcaattc ggcgacaccg
    24301 gcgccggagg aggcggaaac ctcggtctga gtcatttctg aagcctttcg gaaacggccg
    24361 gttcagggcc ctgcgaaatc agcgactgca ccgcgcacga ggggtcaggg aaacagtcgg
    24421 ggaacaaagc gtcaaccgcg atcggccgcc gggtgcacga acggccggcc gtgctgcgac
    24481 gcacaggcgg ggcaaggcga tggggagcgg tgggcaagga ccggaaacgc gggcgggcaa
    24541 ggggggaatt tccccggttg cacgcccggt tccggcccgg cgcggcggtc agtccctgag
    24601 catctgcgcc aggaggaagg ccagttcgag cgactggcgg tggctcagac gtgggtcgca
    24661 cgccgtctcg tagcgccggt gcaggtcctg gacgagcagc ccgtccgcgc cgcccaggca
    24721 ctcggtgacg tcgtcgccgg tcaactccac atggacgccg cccgcatgcg tgcccagcgc
    24781 ccggtgcacc tcgaagaagc cggacacctc gtccaggatg tcgtcgaagc gccgtgtctt
    24841 gtgaccgctg gtcgcctcga aggtgttgcc gtgcatggga tcgcacaccc aggtgaccgc
    24901 gacgccgttg gcggtcacct tctccaccag cccggggagc acgtcgcgga tgcggctcgc
    24961 gcccatgcgg gtcacgaacg tcagccggcc ggggctgttg ccggggttga gccggtcggc
    25021 gtaggcgagg gcctcgtccg cggtgacgga cgggccgagt ttgaccccga tggggttgcg
    25081 gatgcgggcg aagtagtcga cgtgcgcccc gtccaggtca cgggtgcgct ccccgatcca
    25141 caggaagtgg ccgctggtcg cgtacgacag cccggtgcgc gggtcggtgc gggtgagggc
    25201 gtcctcgtag tcgaggagca gcccttcgtg cccggcgaag aactcgacgc cacgggtggc
    25261 gtgggggtcg acgccgcagg ctttcatgaa gcgcagcgag cggtcgatct cgccggccag
    25321 gtcctcgtag cggcggccgg cgggcgagtc gcgtacgaac ccctggttcc aggcgtgcgc
    25381 ctcgcggagg tcggcggagc ctccggtggc gaaggcgcgc accaggttga gggtggccgc
    25441 ggaggagtcg tacatccggc gcagtcggcg ggcgtcgggg gtgcgggacg cggggctgaa
    25501 ctccagcccg ttgaccgcgt ccccacgata ggcgggcagc gtgacgtcgt cacgggtctc
    25561 ggtcggccgt gagcgcggct tggcgtactg gccggccatc cgtcccacct tgaccacggg
    25621 cacctgtgcg gcgtacgtga ggatcacggc catctgcagc agggtgcgca gttttcggcg
    25681 gacggagtcg gtggtggtgc cggtgaacgt ctcggcgcag tcgccgccca tgaggacgaa
    25741 ggcccggccg tgggtgacgt cggccagccg ggcggtgagg cggtcggact cctcggcgga
    25801 gacgagttcg ggtgcgcggg ccagttcggc ggtgacggcg gcgagcagcg ccggatcggg
    25861 ccaccggggc tgctgagcgg ccgtcaggtc gcgccaggtg ctgtgcgccg tgcgcggtac
    25921 gggtgctgtg gtcatgtcgg gttcacgcat cacggccttc gcttcggtcg gcgggacagt
    25981 gggtgggcgc tcggcgggca cggtcatcgg gccccctcgt ggccgcgcgg gcccagccgg
    26041 aacagcgcct cctggaccac gctggccacc agccggccgt cctcgtcgaa gaagcggcca
    26101 caggccaggc cccggccctg gccggcggtc ggggactcgc agtcgtacag cagccaggtg
    26161 tcggcccgga acgggcggtg gaaccacacc gagtggttga ggctgaccat ggtgaccggg
    26221 tcgaggcccc agtagacgcc gtggccgagc aggatcgagt ccacgagcgt caggtcggtg
    26281 gcgtaggcga gcgcggcctg gtgcgacagg ggtgtgtccg ggagccgttc cacggcgcgc
    26341 agccaggcgc ggtgagcagg ccgcccgggt ccgcgtgcgg caccggccca gggcggctcg
    26401 gtctcgtagc gcaggtcgaa ggggcggacg acgtcgggga tcgcgccgag ccgaccggac
    26461 atggggccga gcgcgtgcgc gtacgtcggc caccggtcgg gcgggggtgc tgcgggtgcg
    26521 gtgacggcgt gttcggggcc ctgctcggtg tcctggaacg agacggtgac cgtgcacacg
    26581 gccctctcgc cctggcgtac cgccacctgc cgcaccccga aggaccggcc gtcgtgcaga
    26641 tcctgcacgt ggaagtccag gggacgggcg ggatccgcac cgcgcaggaa gacgatctgc
    26701 gcggcgtgcg cggtacggcc cccgggcacg gtacgggagg ccgcggtcag cgcctgggcg
    26761 agcagttggc cgccgaagac gcggggcggg gcggctgccg ggctgtgtcc gcggaacact
    26821 cctgcttcga tttcctccag atccagtatt tccagcagcg ggctcgtggc cgcgttcttt
    26881 tcggcggctc gcgtttctga catgggagat ggaatccaat ccgcgggagg gcgagaaaga
    26941 gcggtgcgca caacgacgga atgaggggcg ggaaatgcgt gcgaactccg gcacacttcg
    27001 gtgaatttcc cggtggtgca gagccgtcgg ccctcagccg gccgcgggca gcacggtcca
    27061 gcacagcacc gctccggcca cccaccgcac ccttgtccgc agcacgggcc cggcctgccc
    27121 gtgctgccat gcctcgaacc cgtgcgggac gggtcgtacg gcgatgtcac gcagggtccg
    27181 cggcgatgcg gcgcctccgg gcagggcggc gagggccttg aacacggcct ccttggcgga
    27241 gaagaccgtg tgcagcagcc gccgggccgc cgccggatca ccggcggcgg tcgcctccag
    27301 ccatccggcc tcccggggag tcagcaccaa gtgtgccgct tccaggggga gttgatgcag
    27361 ttcaaggtcg acacccaccg tacggcaggt gtccctccgc gcggcaagtg cgaccgccgt
    27421 cccgccggag tgggtcagtg aggccacggt ccggtcgggc accttcggcc gccgaccctc
    27481 gtaggagatg tccggggcgg ggcagccgac cgcgtccagg gcccggcgca gtgcccaccg
    27541 gccggccagg aactcctggc gtcgcgcggc ccccatgcac cgggcgaggc cgcgctcggc
    27601 gggaccgccg ggcagaagcg cggtctcctc ggtgccggcc agaccgagtg ccagaccctg
    27661 tgccgaaagc agcgggcgca gggcccggac ggcgtcggcg aggctgctca cccgcccctg
    27721 gggcaccggt gcacgcaccg tgtcaccgcg gcctcggccc gaccgcgcgg tcgaccaggg
    27781 ctccggcggc accgacgtag gagtccgggt cgacgagtcc ggtcagctcg gcgggggcca
    27841 gggccgcacg gacctcggga agctcggcca gcacctggtg gagcgggcgg tccagggtcc
    27901 gtgcggtcgt ggaggcctcg tcgaccagct cgcgggcgcg ggccttgccg agcgcgggga
    27961 ccaggcgggc ggcgatgcgt tccgtgacga gttgcccgcc ggtgcgggcg aggttctccc
    28021 tcattcggtc ggggtgcacg cgcagtccct cggccagttc gaccgcggtg tacgcggcgc
    28081 cgccgaccag gcgcaggcat tcccgcagcg gctgccattc ggcgtgccag gccccgccgg
    28141 agcgctcgtc ctcggcgagc aggcactgcg tcaggcccgc tgccagcaca gggacctgga
    28201 gagcggcggt gcggatgagg gtggccagga ccgggttgcg cttgtgcggc atggccgagg
    28261 aactgccccg gccgggcacg aacggctcgc tgacctcgcc cagttcggtc cgggtcaggt
    28321 tctgcacatc gacggcgatc ttgcccagcg ctcccgcggt gaacgcgagg gcggcggcga
    28381 cgtccgcgat cggggtgcgc agcgcgtgcc agggcagggc gggccgggac agcccggtct
    28441 cggccgcgaa ggcctcctcc aggtcggtca cgtactcctc gggtgtgcgc cgtacgccgc
    28501 cgatgccggc gtactccagg tatccggcga gtgtgccggc cgcgcccccg agggagaccg
    28561 gcaggtgctg cccggcgacc cgggcgagcc gctcctcggc gtccagcagc gactggcgcc
    28621 agccggccgc cttcagcccg aaggtggtgg gtacggcctg cagcgccagg gtgcggccgg
    28681 ccatcggggt gtcgcggtgt tcggcggcga ggcgggccag ggcctcggcg gcccgcgcca
    28741 ggtccgccct gatgacggtg agcgcgcgcc gaaccaccag catcgcgccg gtgtcgaaga
    28801 tgtcctggct ggtggagccg cggtggacgt agtcggcggc ggccgggacc tcggccgcga
    28861 cgagccgggt gagggactgc accagggcga cgacggggtt ggcggtctcg cgcgcggcga
    28921 gggcgatttc cctgaggtcg aagcgggtgg cgtcggcggc gcgggtgatg gcctcggcgg
    28981 cgaggacggg cagggtgccc agtttcgcct gcgcccgggc cagggcggcc tcggcgtcca
    29041 gcatggcctg cagccaggcc cggtcgctga cggccgcctc gacctcggtg ccggcgcgca
    29101 cgggcgagag cagcccggta tcggccatgt ccttcatatg atcactcctg tgatgtccgc
    29161 gtcgggcacg ggcgcgtcga ccgtcggctc cagctccagc accgcgcggg cgacggcgtc
    29221 ggagtcaccg agggtcaccg agtccacgcc gggccggatg ccggccgcgg tggcccagtg
    29281 caccgactcc gtgggcactc cgtacgcgaa gcggcggggg tgttcgcggc cctgtgcgtc
    29341 gagcagacgg taggggcgtg tgccgacggc gagtccgccg gtgtggtagg tggtgccgca
    29401 ggcggcggag atgcggtggg tggtggcctg gcccgtgccg agcaggtgca gcagcagcgg
    29461 gtcggcggtg cggcgcacgt ccgcgtcggg gatccgggcc tcgatcagcg cggtggcacg
    29521 caccggtggc ccgggtacgg ccgtggacgt ggtgacgtac gtcgaggagc gcaggtcgat
    29581 gcggatgacc gtgtccgggc cggtcagttc caggaccccg gcctcgatca gtgccgccgt
    29641 ctcctcgatc cgcgaggcgg gcggcccgat ggacaagaac gcgttcaggg gtgtgtacca
    29701 ccggtcgagg tcgtcgcgat gggagtcgcc gtcgaggccg ccgtggtcga ccgccagccg
    29761 gacctcgttg cgcagatcac gcaggacgtc cagggccgct ttgagcgggt tgctcacgtt
    29821 gccaccacgg gcctggcgta cgtccgcggc caggtgggcg ctcagccagg cctggaagtc
    29881 ggcccggtcg gcgaaggtgc ggccggcgta gggccgctcc agccgcgccc agttccagcg
    29941 ctcctcggcg gtgatgccgt aggcgtccag gaggccgggc agctccgtct cgtcggcgtg
    30001 cagatagccg gtgacgaggc gctcgcgatc cgcgccccgg ccgcgggcgg ccagcagggc
    30061 gccgtagtag acgctctcca cctctcgggc gatcagcggc cacaggtccc ggcggaagtc
    30121 gaggccctcg cccggcgggc gcgagccccg cagcgcggtg acgtggtcgg cggtcagcag
    30181 ccgggggtgg tgacggccgt gcgcgccctt ctcgttctcg ccgcgggcgt ggtacgggat
    30241 gccccgccgg gaggtggcga agagcaccgg ttcgttgccc gagggccggt acaccaggcg
    30301 ctccgccccg tcacgggcga aggtgccgcc gcggcccgtg gtgagcaggg ccatgtagtc
    30361 gaagaagttc aggccgagcc cgcgcagcag gacgtgctca ccgggcgcga tcacgtcgag
    30421 gtcgacgtcc gccgggttgg cgggcggcag ataggtcagg ccgtgcaccc gggcgagctg
    30481 agcatggcgc tcctcgcggg ccgtcggccg gttcgcgagg tgtccctggg caaggacgac
    30541 ggcgtccagc ggctcgagcc aagtgccgtc ctccaggcgt acggcctggg cgccccggtg
    30601 ctcgccggac aggtcagtca ccgccaccgc gcgctgtcgg tacgtccgca cggtcacatg
    30661 ggcgggggcg tcccgcacca cgcgctggaa catgtcgcgc aggtagcagc cgtagaaggc
    30721 ccgtgacggg taggagtcgg gggtcaggtc ccgggcctcg gccagggtct ggtcgtcgca
    30781 tgccccgaag ccgcctccgg cgagccggcg tgcccactcg taaaggctgg gtcccggttc
    30841 gaccgggccg tcgatgcgca cactcttgtc ggtgaacacg gttatctggg aggcgacggt
    30901 gttcatcagc agcaggcggg actgctcggg ccgccacacg gctccggctc ccggcgtgcc
    30961 ggggtccacc acgtgaacgg tcacggcgga gtgagtgggc gtcatccgtg cgttggcgca
    31021 cagccgttcc agcacggaca gtccgcgggg tccggcgccg acgatgcaca gggcaagggc
    31081 actgctgggc atggaagggt atccgtttca cgaggaggca gcccgccgcc gcgcgtcagc
    31141 gcaggggccg ggggccgcag cgggttcggc cggctgaccg gccggaccgg gttcgggcgc
    31201 ggccgggccg ggttcggcgc gtgggtttcg cacgatgtgc ggatgtcgtg cggtgcgggg
    31261 gcacccgagt gcccccgcac cgccgcgccc gaatcagccg gacgccgaac atacccaaca
    31321 cccgggccgt ccaaggggcg gccggcgaac agcgcctgac gcccgcggaa ggttcaggag
    31381 gcgacggacg tcaccgtcac ctcgccggcc tcgatacggg cggcgaaccg gtgccactgc
    31441 tgggcgcatt ccatggccag cgccgagacg acctgcgcgc ggtgccgcgg gaccgagcgg
    31501 gcgatactgt cccagcgctg cgggtgcagg acgtgcatct ccatcatgcg cagcagctgg
    31561 cggccgtcct cggtgagccg cagcgatggg tcgcggcaca tccggcggaa catgtcgatc
    31621 cagtcgaggt tgtccaccat cggctgccgc ggccgctcat ccgtctccca gcccggtgcg
    31681 acgaccgacc acggctgtgg gcggggtgcg ctctgcgggg ccgggggcgt ggtgggtttc
    31741 tcgccgcgcc ggtggctggg cacgatgtcg tcaccgcggt cgaggcgggc gcggacatcg
    31801 cgcacggtgc ccggtgagac gcccgcctgt ttcgcgatgg cacgcagcga ggcgtgcggc
    31861 gactcaagga tgagccggcc ggcgatgcgg cggccctccg cgctgttcag tgggcgtccc
    31921 cgcccgtcgc gcccgacgcg tgtggtggcc tcgcccaggt cgccgagctt gtggcgctgg
    31981 gcgcccacgg tcttggacga cagaccggtg acccgcgcga tggcacggtc ggaccactcc
    32041 ggatgggagc cgaggatgcg taccgcggcc gccctgcggt cggcgaggga gagcggcagg
    32101 ccgtgcctga cgttcgtcct gacggcgaag acgaaggcgt cctccgcgga tccgtcgaag
    32161 aagcggacct cgatctcggt ctcgccgcgc aggaccgcgg ccttcaggcg gtgccgtccg
    32221 tcgacgacct ccatggtggc gcggtggacg accagcggtg gccgtgcctc gtcggagtcc
    32281 gccagcagac gtacgtgttc ctcgtcctcc gcgttgacgc gcggtgagcg cccgggccgg
    32341 agcgaggcga ccggtacccg gtgcacctcg gagagccggt cctccgcact ggctctcgca
    32401 cgttccgcct cgtgagcggc ctgctgtacg tcatcggcca taaccatgtc gctgacacct
    32461 tccccgttgg atgccgcatg atcgtcactc gaagattaca aaccagacga tcggttttca
    32521 acatcctcac cgcagtgggc aaccgaggaa gttccccgtt tgcacggccc atctgtccat
    32581 gtttataggg aatttgacgc cagctcgccc gatcaaagaa ggacgcccgg tgcggcaaaa
    32641 taacccgacg cgcgtcctgc tacgcgatca taggtcttta cctttccgtg accatcctca
    32701 ctgctatcac ccagggatcc cacatgatcc aatccagagc ggtgcgcacg cgccaggaac
    32761 tgatccgggc cgcggcggag gcgttcgcgc tccgcagcta ccaccaggcg acgatcgccg
    32821 acatcagcga ggccgccggg gtcagccccg gcggcctgca cttccacttc acgaacaagg
    32881 cggccatagc cgaggcggtg gaggacgaag cggcccaact gctgcgcgcc acctgtcgcg
    32941 acgcacgctc gggcgcacac accagcctcc aggcgctcat cgacgcctcg cacgcgatcg
    33001 ccgcactgct cagcgggaac atcgtcgccc gcgcaggcct cctcctcggc caggagccca
    33061 cccgctcttc gaagctgtcc ctgcatcagg agtgggccga gtgcattcac ctgctggtcc
    33121 gccgcgcggt cgaggagggg cagctgtcct ccgacgtctc cccgcgggac ctgtacacgg
    33181 cggtactcgc ggcgaccgtg ggactggagg cgctcggccg aggcgacggg cgctggctca
    33241 ccccgcagac actcgcctcg ttctggcgtc tgctcctgcc ccgcatctgc ccgccgcacc
    33301 gggccgtcca cctcaacccg accgggacgg cggcccgttg accattggcg gatattctgt
    33361 atccatgata gccatttaat gcccagtcag aacgagacat cagaacgaca ttcgggagaa
    33421 ggcatggccc tcactcgctc ggactcgtca gcagcctccg aggcggtgca gccaccccca
    33481 ggatcgcgtg agtggcgtgt gctgtccgtg gcgctcatcg ccgcgttcat ggcggtcttc
    33541 gacctgtacg tggtcaacat cgccgccccg accctgcgca ccgacctgca cgccggtgac
    33601 gcctctctgg aactcgtggt gtccggctac gcgttcacct acgcggcggg cctggtaacc
    33661 gggggccggc tcggcgaccg cttcggctac cgcacgatgt tcgtcgccgg catggcggcc
    33721 ttctccgtcg cctccctgct gtgcgcgctg gccacgaccc ccggccaact ggtcgccgcc
    33781 cgactgctgc agggcctgac cgccgctgcg atggtccccc aggtcctcgc cctgatcacc
    33841 gtcactttcc cggccgccca ccgcgcccgg gcgaccggct ggtacggcgc ggtcagcggc
    33901 ctcggcgccc tgtgcgggca gatccttggc ggcctgatcc tcaaggcgga cctcttcggc
    33961 ctcggctggc gcggcatctt cgtggtcaac gtgcccgtcg gcgtgatcgc ggtggcgctc
    34021 ggcctgaccg ttctgccgcg caccccggcg gcgcagaagg ccaagttcga cccgatcggc
    34081 gcgctcaccg tctcactggc cctggccctg gtgctggtcc cgctctccct cggccgggag
    34141 tccggctggc cgctgtggac ctggctctgc ctgatcgcct cggtcccggt catgttcgcg
    34201 gcgatcgcct ggcagcggtc cctgctccgg cgcggcggcg cgcccatcat caacaccgcc
    34261 ctgttccgca accggcccta ctcgctgatg ctgtcggccg cttcgacgta ccagctgtac
    34321 ttcggcagct tcctgttcgc cctcaccctg gtggtgcaga gctggctcgg cacctccccc
    34381 gaccgggccg cactcgtgtt cctgctccag ggcgtactgt tcaccgtcgc gtccatggtc
    34441 ggcggaaagc tgatcgcccg gtaccgcacc ggtgtaccgg tggtgggcgg cgtcctggtg
    34501 atcgcaggcc tgctgctgat caccggcgaa ctggcggcgg gcggacccgg gttgtctgcc
    34561 tggtggctcg tgccgccgct ggccgtgatc ggcctgggca acggcctgct gctgcccccg
    34621 ctgatcggcg gcgcgctgtc ccgcgtgcag ccggagcagg cgggcgccgc ctccggaacc
    34681 ctgaacacgg cccagcagtt cgccaattcg ctcggcgtca ccgtgatcgg caccgtgttc
    34741 ttcgcgctcg ccggaccggc gctgcactcg gcgggccacg ccatggagat cctcaacgtg
    34801 gtgtacgccc tcctgaccgc cgccgtgatc gccctggtga agctggcgga ccgggccggc
    34861 cgctgacgcg cccgccgctg ccccgacccc gcgacctgcc accacccgcc ccgcccgtac
    34921 tgcccgttgt cgtcctgtaa gtctcccgtc accgtgtgag gagaagctgg cgtgtccgct
    34981 cagtcgcaag gccgtagctg gccgaaactg ctggattcgc tgctgcgccg cagcgacctg
    35041 cacgcgcggg acaccgcttg ggccatggac caggtgatgt ccggcgccgc cccacccgcc
    35101 gctcttgcag gcctgttggt ggccttgcgc gccaagggcg agaccgtcga ggaggtcgag
    35161 gggctggtgc gctccgcgta ccggcacgcg ctgccgctgg agatcgccgg tcccgcgctc
    35221 gacatcgtcg gcaccggcgg ggacggctcc gacagcgtca acgtctcgac gatgtcagcg
    35281 atcgtggcgg cgggtgccgg ggcccgggtg gtcaagcacg gcaaccgttc cgcgtcctcc
    35341 gcctgcggct cggccgacgt cctggaggaa ctgggtgtgg tgctcgacct gtccccgcaa
    35401 gacgtccggg acgtggccga ggacgtcggc atcaccttct gtttcgcccg gctcttccat
    35461 cctgcgatgc gccacgccgc gcccacccgg cgctcgctcg gggtacgtac ggtgttcaat
    35521 ctgctcgggc cgctgtgcaa tccggcccgg ccctcggccc aggcggtggg tgtggcggat
    35581 ccggccgcgg caccgctgat cgcgagggta ctcgcccgcc gcggcgtgtc ggccctggtc
    35641 ttccggggcg acgacggagt ggacgagttg tcggtcacca cgacctccgc catctggtcg
    35701 gtcaccggct cgggaatccg gtccgagacc ttcgaccctc gcgacatcgg cttcacgctg
    35761 gccagccccg acgctctccg cggtggcgac cccgcccaca acgcccgggt ggcccgtgac
    35821 attctggccg gcgaacaggg gccggtccgc gacgccgtgc tcctgtcggc cgccgccggt
    35881 ctcgccgcgc tggagccgtg cgaccgtccg gtggccgaac gcctggagga cggcgtacga
    35941 cgagccgccg cgtccatcga ctcgggggcc gccgcgagca tcctggaacg ctgggtcgcg
    36001 gtcaccgtga aacgcgcgct ggacgcctga gaaaaccgaa ggcggtaccg gccgaggggg
    36061 atccccggcc ggtaccgcct tgtcgtgtgc gcggccgcta cgtcacgtac ctcgcgcgaa
    36121 ggcccgcaag gaccgctcga tccaggcggc gtacgtgccc gcggggcggc ccagcagccg
    36181 cgccacggtg tcggccacgc ctcccttcgc atcggccgac cgcccgtcgg cccggtccac
    36241 gagggcctgg gccaccggtt ccgggtagcg ccggtgcagc atcgccagcg tttcctcccg
    36301 ggaacgctcg gcgaaggaca gcgggcgacc gagcgccccg gacaggatcc gggtctgctc
    36361 ccgggccgtc agcgcctcgg ggccggtcag cgggtaggcc cgtccggcat gcccgtcctc
    36421 ggtgaggacc cgggccgcca ccgccgcgac gtccgccgga tcgacacagg ccgacgggac
    36481 gtcccccggc cagtgccgca ccgtgtccgt ggccttcacc tcggcggccc acgccagggt
    36541 gttggtcatg aacgcgcggg gccgcagcag tgtccagtcc gagcccgagg cccggatgcg
    36601 gtcctcgctc tcccgctgcc agcgggtcac caggtcccgc gcccgtgcct gggtggcggc
    36661 gagcgcggac aacttcacca ggtggcgcac acccgtgtcg gccgcggccc gcaccaggtg
    36721 ggcgtcctgc tccgggcggg tcgggtcgga cgtgatgacg agaaccgccc ggacgccggt
    36781 catggcccgc cgaagcgtct cgggagcgtc gaagtccccg atggcgacct gcgcttcggc
    36841 gccgggttcc ggcgccggtg cgcgaaccgc gtcgcgcacc agcagccgga cggggtggcc
    36901 cgaacgcatc agggtccggg cggtgagccg ccccaccgtg ccgctcgcgc cagtgatcag
    36961 gatcaccgtg ctcctcgtgt tgtcatcgcg cggtcacccc gccgtcgacc ggcacggtcg
    37021 ccccggtgac gaaggacgag ccgtcgccga gcagccacgc ggcggccctg gccacctcct
    37081 ccggctccgc gagcctgccc accatcgact cggaggccag ccggtcctcc agacccgggt
    37141 actggtcgag cgcctcttgg agcagctcgg tgcgggtggc gccgatggcc aggacgttgg
    37201 cccggatccc ctgggacccg tactggtccg ccgccgcctt ggtcaggccg atcacggcgt
    37261 gcttggccgc gatgtagggg gcgccgggca gaaagtggcc gacgaccccg gcggtgctcg
    37321 acgagctgac cacggcgccg ccgcccgcgg tggcgatcat cgcggggatc tggcggcgca
    37381 gacagttcca cacacctcgc acgttcacgt cgaagacccg gtcgtactcg gagtcctccg
    37441 tcagatgcag cggcgtacgg ggagcgcccc aaccggcgtt gttgaacgcg ccgtccagcc
    37501 gcccataggt ctcgacagcc gcctcgacca cacgccgtac atcctgtgcc gaggtgacgt
    37561 caccggcgac cgcgtgggcc gggccacggg tcgcagtgat ctccctggcc aatgcctcga
    37621 ggggctcagg gttgcgggcc atcagcacta cgcgggcgcc ttcggcgctg aacacacggg
    37681 cggccgcggc tccgatgccg ctggaggcac cggtgatcat gacgaccttg ccggcgagca
    37741 tgccctggga gtgcgtcata ccgccctccc cgcgagctgg agcaccggct gcctctgctc
    37801 ggacgggtac ggaaggaacg tgagctccag tccgtccccg cacgggctca gggggatcac
    37861 tccgcgggcc gcctcctggt cgcgctgcca cacctgcacc ggtacctcga cggctcctcc
    37921 gtccggccgg gtcggtgtgc cggtggtgag gtagcagggc aggtcgtgct cgacatagtg
    37981 ggagaaggcc gtctgcatac gggccgtcac cgcgcccgac agaccggtca cggcctgggc
    38041 cgtctgccgc atcgcctcga tgatcgccat gcccgggaca tgatcgagcg ggtggtcgta
    38101 gaggaccggg tgatcgcgtt cggctcgcag caggaacgta ccgggcagtc cactcgacgc
    38161 gatgacgacg tcctggggac gtacccggcc cacggcgacc ggctccacgg gagccggaag
    38221 tgcgggcagg gccggatcct cggaggagcg ggcctcggcc cgcagccgcc ggtagacgcc
    38281 cggcgacatg cagcggtagt cgaacgtacc cgaagcgacc tcccggccct cgcgcctgag
    38341 caccatcgtg ccccggacgc cgaacagcgt ccggccgcgc cgccgcacct ccaggcagtt
    38401 cacctccaga tccagccggg tccgggtgtc ggccggagcc agcgcctccc agtcgaccgt
    38461 gtggctcagc tcgttcatga caaagctgtg ccccttcggc acgtcgtacg cgacgtgacc
    38521 gacgaggatc cccgcctgcc gcatcgtctc ggacaccagt tgcggatcac tgccgccgtc
    38581 cgcgcacggg ccgtagaacc tgtggtcccg cggccagtgc acagagacat tgaaacgatt
    38641 ctcctcgcat tgctccaccc ccgtgacgag cacctgctcg ccgttgcggc ggtgcaccag
    38701 gtccttcagc agagtcgcac tccgcgtcgc agccaggcac acgtcacctc accagctttc
    38761 gttccacccc cgcccagcgc gggaagatcg ggagccaata aaaactgact gatcggtttt
    38821 gtcaatgaga attgacgacc ttatttggac gacatatccg aaatgtctca tttgatggag
    38881 caaacaaacc atccagttgt tctcaagaac ggggatagga tgcaccaagc aatacggccc
    38941 aaaggagaag gaacgcagcc cggaggaagg gacattggcc cgccaagaac gcgctttgcg
    39001 cacccgaaga aaactcatcg atgccgccgc ggccgtcatc agcaagcgcg gctaccgggc
    39061 tgccacgatc gccgacatca tggaggccgg cgacgtcacc agaggcgcgc tctacttcca
    39121 cttcagctcg aagcgggcgc tcgccgacgc catcatccag gagcagaccc tcccctacac
    39181 ggtgaccgcg cccggctccc cgctccagcg gctcatttcg atgagcctgg agatcggacg
    39241 ggggctgcag aacgacccgt tgctcagagc gggcacccgc attaccgtcg atacggtctt
    39301 cgacgatgcg ccggtcaccc cgttcgagga gtggaacacg gtggccgtcg cgctgctgac
    39361 ggaggcccgc gacgccgggg agctgctgcc gcacatcgat cccggaacct gtggcgagtt
    39421 catcgtggcc gccttcaccg gagtccagct cttctcccag gcggcgtccg gtcacgcgga
    39481 cctgtcggag cgcatcacca acctgtggcg actgctgctg ccgggcatcg cccatcccgc
    39541 ggcgatcacc tacctgaatc cgaccttccc cgacagccgc cccggagccc cggccgacca
    39601 gcccctcgaa ccctcggacg cctgaagcac gtcggcaccc gccgccacgg gtgaaacggc
    39661 gttccgacac gctgctcgcg cggctcatga ccgggcgccg gcggcggcgc aagcgctgag
    39721 gcatgcgctg tgacgtcgca gcggttcggc ttcgagagcg gcacgctcta cgcctacagc
    39781 caggtcacgc aggaccgccc cgcgacgagc gcgggatcct gcacggccac gcagtccgtc
    39841 atcacaccgg ctccgccggc gcaccggcat gcccgcggcc cggcctacgg tacgccgccg
    39901 accccggacc gcgtctcggg gctgccactg atcctctcag gtcgccgtct gtgccgccca
    39961 cgccctgacc gccgctccgc cgttgcctca ttgaccgccc gtgcggcaag cgggccgccg
    40021 ccccggcggc tgcggctgcg gctgcggcct gacaggtggt gcgctcgcgg gctcgatgtc
    40081 ggtaccgaac cctgaactca gttcctgtgc ttcgtctcgc gggcaccggt acgcgcgtca
    40141 gggtgagcgg cgtaacaggt cggccccgcc tgtcggttga cggcaacggg acggacgcgt
    40201 gctcgcggcc gttcaggcag cggccgagca caccgacccg gtcctggtag atcgcctcga
    40261 cctcgctgag cacggcgtcg tgctgctccg tgaagccggc gcccgcagct cgccgtgccc
    40321 gcaccccgcg gacagaatcg cggcctccgc ctccgacgcc cgctgtcccg gccccggttg
    40381 ccatgccgga cggcgtccgg gctgatgccg cctggggacg tgccgtccga ggaaagcgtg
    40441 cgtccgtccc cgctcgggtg cgggacttgt gacgtttgaa cgttcgaatg cgctggaatt
    40501 ccagggcact tccgtgacgg ctgtgccctg cgatgacgga tgacaacgac aaccggtctt
    40561 cggccttcgg ctgaccagcg accccgccgg tcccgcccgc tctgcaccac ggggctggac
    40621 cggcgggcac ccggccctca gaccggggcc gcccgacgac cagttgatcc ccgccgagaa
    40681 gcggccgccg gctgcacgcc cgtccccgcg cgggcgacga tcacacgggc ggccacgatc
    40741 accgcacgat cgcgacagcc acgcccaccc cgcccctcgg cccgaccacg tgacccatcc
    40801 gcctcggccc cgaaggccaa agcgcgaaaa tctccgcaag tcggcgggtc ttccactgcc
    40861 agaaaaccgt caaccgcatg actccggtat cccgcccctg ggggtgggcc cgggccggga
    40921 gcccttgccg agaccgcttt ccgtcctacg gtctgacgca tgtccgaaac aggagcttcc
    40981 ccactcccct ccacgccccc ggcacgctct ccgctcttcc gcgccgagca gttcgtgtgg
    41041 ctcaacgcgc gcgtgctgga gcagcacctc ttcgcgtacc gctttctgca cggcaccccg
    41101 gacgcggtgg aagcggcact ggacgcctac cgcaacgagg acggcgggta cgggcacggg
    41161 ctggagcccg atctgcgcgg gcccatgagc cagcccctgc acaccgcgca cgctctgcgc
    41221 gtcctggacg ccatcgggcg ctgcggcggg cagcgggtcg agcgggtgtg ccgctatctg
    41281 acgtcggtct ccaccgcgga cggcgccctg ccggcgatcc gtccgagcca gcgcgggtat
    41341 ccgacggcgc cgttcgtccc ggtcgtcgac gaccctccca gcgagctgct cgccaccggg
    41401 ccggtggtcg ggctgctgca ccgcaacgag gtgtggcacg cctggctgtt ccgggccacc
    41461 gacttctgct ggcaggcggt ggagtccctg ggcaagtccc acccgtacga ggtggaggcc
    41521 gccgtggcct tcctggactc ggctcccgac cgctcgcgcg cggaggccgc ggcggaccgg
    41581 ctgggccgca tggtgcggga gcaacggctc gcggtcctgg accccgaccg gctcgacgcg
    41641 tatccggtcg cctccggcta tgccccgggc gagcaccact tcccgcacga cttcgccagg
    41701 agtccggagt cgttcgcgcg cgcgtggttc acggacgacg agatggcccg ctccctggac
    41761 cacctggccg ccgagcagca ggacgacggc ggctggccca tcagctggcg ccagtgggcc
    41821 ccggcccccg cactggaagc gcgctccctg gtgacgatcg aggcactgca aaccctccgg
    41881 tcctacggcc gcttcgtggg ctgagccgga cggccgcgcc ggtcgcgtgt cacccgccga
    41941 cggcctgggc cgcggtgcgc atgggcgggc agcaggccga ggcccggcgg caccgccagg
    42001 cccgcgcccg ctcctcaccg aacggcgttt gcccaggtca gcgcgattgt cagtggtcgg
    42061 gtgcaggatg gacgcatggt cagctccgca caccgagccc tcgatggctt ctcacccgcg
    42121 acccgcggct ggttcacggg ggcgttctcc gcgcccaccg cggcccaggc cggcgcgtgg
    42181 cgggccatcg gcgcgggctc ggacgtgctg gtggtggccc cgaccggttc gggcaagacg
    42241 ctggccgcgt tcctcgccgc cctggaccag ctcgcctcgg ccccgccccc ggccgacccg
    42301 aggaaacgct gccgggtgct gtatgtgtcc ccgctcaagg ccctcgcggt cgacgtcgag
    42361 cggaatctgc gcagcccgct gaccggcatc cgccaggagt cggtgcgcct gggcctgccc
    42421 gagcccgagg tcagggtcgg catccgctcc ggcgacaccc cggcggccga gcggcgcgcc
    42481 ctgtccaccc gcccgccgga catcctgatc accacccccg agtcgctgtt cctgatgctg
    42541 acctcggcca cgcgcgacgc gcttacgggc gtggagacgg tgatcctgga cgaggtgcac
    42601 gcggtcgcgg gcaccaagcg cggcgcccat ctcgcgctct ccctggagcg gctcgacgag
    42661 ctgttgccga agccggcccg ccggatcggc ctgtcggcca ccgtccgccc ggtggacgag
    42721 gtggcccggt atctctcacc gcgccgcaag gtggagatcg tccagccgga gtcgggcaag
    42781 gagttcgacc tgtccgtcgt cgtcccggtc gaggacatgg gcgagctggg cggctccccg
    42841 gcggcggacg ctgctgaggg cgcggagcgg ccgtcgatct ggccgcatgt ggaggagcgg
    42901 atcgccgacc tggtccaggc ccaccgttcg accatcgtgt tcgccaactc gcggcgcctg
    42961 gccgagcgcc tgtgcaaccg gctcaatgag atcgcgtacg agcgggcgac tggcgagacg
    43021 ctggaggagc atcactcccc ggcccagctg atgggcggct cgggcgcggc ccagggcgca
    43081 cccccggtga tcgcccgcgc gcaccacggc tcggtctcca aggagcagcg tgccctggtc
    43141 gaggaggacc tgaaggcggg ccggctgccc gccgtggtcg ccacgtccag cctggaactg
    43201 ggcatcgaca tgggcgccgt cgacctggtc gtgcaggtcg agtccccgcc gtccgtcgcc
    43261 tccgggctcc agcgcgtcgg ccgcgcgggg caccaggtgg gcgccgtctc caccggcgtg
    43321 gtcttcccca agtaccgggg tgacctcgtc caggcggccg tggtcaccga gcggatgcgc
    43381 tcgggctcga tcgagtccct gaaggtcccc gcgaacccgc tggacgtgct cgcccagcag
    43441 ctggtcgcca tgactgcgct ggacacctgg cagttcgacg acctgctcgc cgcggtccgc
    43501 cgcgcggcgc ccttcgcctc gctgcccgag tcggcgttca cggcgactct cgacatgctt
    43561 gcgggccggt atccgtccga cgcgttcgcg gagctgcgcc cgcgcgtggt gtgggaccgc
    43621 gtgaccggcg agatcaccgg tcggccgggc gcccagcgcc tcgccgtcac ctcgggcggc
    43681 acgatccccg accgcgg
//
