LOCUS       NZ_CM002285            43252 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1578762
            Orig. end                         :: 1622014
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..43252
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /product="NAPAA"
                     /region_number="11"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="(AMP-binding and TIGR02353)"
                     /tool="antismash"
     cand_cluster    1..43252
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="NAPAA"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..43252
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:23252](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..23252)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     regulatory      complement(617..796)
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as a
                     genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(797..810)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.49"
                     /tool="antismash"
     gene            complement(<1244..>1360)
                     /locus_tag="M878_RS96150"
                     /pseudo=""
     CDS             complement(<1244..1360)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013350597.1"
                     /locus_tag="M878_RS96150"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS481 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGQPVRRFERARPGELVHIDAKKRCRIPDGGGHEALGRA"
     gene            complement(1586..2281)
                     /locus_tag="M878_RS57025"
                     /old_locus_tag="M878_07415"
     CDS             complement(1586..2281)
                     /GO_function="GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607354.1"
                     /locus_tag="M878_RS57025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07415"
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="WP_023545474.1"
                     /transl_table=11
                     /translation="MSFFTIGHRGVMAAEPENTLRSFLRAEREGLDGIELDLHLSKDGE
                     LVVMHDETLDRTTDGSGPIADQKLRKLKKLDAGLGERIPTFGEVLDAVGPTLPIQAEIK
                     DVAAARSLAKVLTDRDLLDRVSVLSFHDVALIEIHNLLPRARTVLVAGPSAHRDTFVGR
                     AQKVGSTLVSVELRQLNRAIVEKCGAAGIDVMAWTVNDERDLALARALGLVGCVTDHPG
                     MKRLVEATA"
     gene            2533..2745
                     /locus_tag="M878_RS57030"
                     /old_locus_tag="M878_07420"
     CDS             2533..2745
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS57030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_07420"
                     /product="hypothetical protein"
                     /protein_id="WP_023545475.1"
                     /transl_table=11
                     /translation="MVGGLLPGTLLASLLSAPSAFAGGGNGLGGDIGLPAGGEFSGADF
                     SASDLAGGSWDFGSDGGGDFGDGDW"
     gene            complement(2918..4414)
                     /locus_tag="M878_RS92140"
                     /old_locus_tag="M878_07425"
     CDS             complement(2918..4414)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="M878_RS92140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07425"
                     /product="protein kinase"
                     /protein_id="WP_078630214.1"
                     /sec_met_domain="Pkinase (E-value: 7.7e-52, bitscore:
                     175.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGEALVGRDTVLSGRYELVERLGQGGMGTVHRGVDRQLRRTVAV
                     KLLSSALAHDPQSRARFRREAHAAAALNHPAVAIIHDVGEEPDPDGPRPYLVMEYVSGS
                     TLAEVLRDGPLPVAEAIETACAVLDALQHSHEHGIVHRDIKPSNIMRTGPGTVKVLDFG
                     IAKAFTETATRITGSGAAIGTPAYLSPEQISGAEIDHRADLYAMGCLLHELLTGQPPFR
                     GESPFAVMHQHLFAEPEPVSRLRSHVPSAVEAVIQCALRKDPKERFADARQMGDALAGV
                     LAQSAMPTAQAPAPFPPTTRSGTRTALHHRFALRPTVDSALALLGCLLSLLCARGHVVD
                     TAHFGWVATAAGLLGLVTLPWSGRLSCAVGWGPVAEAVAVNSELRRANDGWAHSYLGIA
                     ALLALTAACCLVGAARSKEGGAGSLVAFWFCATASVWYVLDDLHKLFVFYLLLSLVTIA
                     TMLWETRVHVRRRGGTRRAALAGQPVSAAPQARPLARRLD"
     misc_feature    complement(4397..4399)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4632..5606
                     /locus_tag="M878_RS57035"
                     /old_locus_tag="M878_07435"
     CDS             4632..5606
                     /GO_function="GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143462.1"
                     /locus_tag="M878_RS57035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07435"
                     /product="magnesium transporter CorA family protein"
                     /protein_id="WP_023545478.1"
                     /transl_table=11
                     /translation="MTRTRLYRSGNLVLEDFPTADISEYVNDPDVAVWLDLCDPCSADF
                     AMISEEFGLHELAVEDARQEHQRPKLDRYRTHAFLSAYVVSTDESSGRLTASELSVFIT
                     PTALITIRPNEGFDIEKVVERWDNNSDLAKYGVGFLLHGLLDHIVDGHFAAVQDLDDRI
                     EAVEDLLFDEGRQQMDSVQRDSYALRKNLTRLRRVVLPMREVVNSLLRRDLHIVAEPLL
                     PYYQDVYDHVLRAIEWTESLRDMITSIMETNLTVQGNRMNLIMKKVTSWASIIAVPTAV
                     TGFYGQNVPYPGFNTHVGFLTSTGVMAVGTVVLYLVFKRKDWI"
     protocluster    5001..40851
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:25851](-)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(20001..25851)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="2"
     gene            complement(5584..5826)
                     /locus_tag="M878_RS99565"
     CDS             complement(5584..5826)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025180.4"
                     /locus_tag="M878_RS99565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_280923662.1"
                     /transl_table=11
                     /translation="MRHRLVVVLGLTACAVLAGTTSLPAVGEWIADAPAHVLEAAPPRS
                     SGCSARGGWRTVHVMPWLRRATGAGRSVLRSSPCA"
     gene            6786..8084
                     /locus_tag="M878_RS57040"
                     /old_locus_tag="M878_07440"
     CDS             6786..8084
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012926.4"
                     /locus_tag="M878_RS57040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07440"
                     /product="glycoside hydrolase family 15 protein"
                     /protein_id="WP_209445501.1"
                     /transl_table=11
                     /translation="MYTYMFRNIASDGFVFSDPQSPGDISRDSKPGCIIAAPSFPADTP
                     GIDEDYVFNWVRDGAITAMEVAKADMLTRPGGTVQTLNDYVQFADLCHSSIQPPLTKGH
                     ACFNIAGDARPWTEQNDGPALQTVTILAAYDQLDLGTQKRAVDLVNANVAYLLGVYQGP
                     TTNLWEEHSGYSFFARSAQLRCFEEVQASTIVGIDKPTGLRPAIKWLRQALAGHWDGIK
                     YVSMLADPGDGAQPSPQNPVVSGYDPNIDIVQSAVYGALPVTDTKLLATAAQLRSQWEE
                     GGIAFYSINKADKEAFGIGPLFGRYPGDVYDGDTAHPVLGGHPWALSTCNVAELHYKLA
                     SEIKSSGKVPVDDLSAPFFAQSGIDASTAPAAAAAALTATGDAMVRAVVYHSDNLELSE
                     QFDGTTGFERSVHNLTWSYAAYLSAMRARAEAV"
     gene            8161..10086
                     /locus_tag="M878_RS57045"
                     /old_locus_tag="M878_07445"
     CDS             8161..10086
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017050.4"
                     /locus_tag="M878_RS57045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07445"
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_023545480.1"
                     /transl_table=11
                     /translation="MYAKFPEGAAKRTDPAAAAEVLYDAVIVGGGIAGALIASRLSDAG
                     KRVLILEAGPAEDLTLRGYESYLDRFYSATSKDNQSPYPVFANAPMPRGTDARRIFPGA
                     PDASAYIVQSGPFATDTTYTRVLGGTTMHWEAKTLRMLPEDFRMRTLYGEGADWPLTYE
                     DLAPYYNEAEREIGVSADVEDQAYLGITFDEGYVFPMKGLPLSYLDRMVAKDLDGMPVE
                     LDGEQRELRVRPFPQGRNGIPNPAYDGGKGYLPRGAVSTYQVEVGGRCQGNNNCVPICP
                     VQAKYNAGKTLAVALQSGRVDLVAQAVAHKVHVDEQTRRVTEIEYRRYDRPDSPGFTSM
                     RARGRLFILAANAVENPRLMLASGLRSSSGLMGRNFMDHAYLLAWALLPEVAGTFRGTN
                     CTGGITDLRGGRFRRRQAAFSVDIHNDGWGWARGAPMTDLIDLVDAGGRHGESLRQGLV
                     DRVSRQLQLAFMVEVPANPSNRITVDPAYTDHLGNMRPILTYDIPDYTMRGVAYARQLS
                     RRIFARLGAEDHTEYDPNFWGYAVHAGEGYEIRGGNHLAGTHTMGRDPSTSVVDPDQRC
                     WDHENLYLVGGGSMPTVGTSNVTLTIAALCLRSVRAMLAQLDAETAPIEVTSNAATRRQ
                     PQGVTR"
     gene            10083..11195
                     /locus_tag="M878_RS57050"
                     /old_locus_tag="M878_07450"
     CDS             10083..11195
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024306.4"
                     /locus_tag="M878_RS57050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07450"
                     /product="ferritin-like protein"
                     /protein_id="WP_023545481.1"
                     /transl_table=11
                     /translation="MTASTIEKRDDLISYLHAAMALEHATIPPYLTAYYSIHSTTNSDA
                     AHIIRVAAVEEMLHLTLVANVLNAIGGKPDLTRPGFVPSYPAYLPDGEDDFTVDLRPFS
                     PEAVETFCKIERPGKAPSAGARLVRRADSGRPLLASSPTAEGMRFYSIGEFYAEIIEGL
                     EKVAADDPGLFCGNPALQVGPEYYYSGGGAVIVVSDLDSARQALRFIAAQGEGLDSGIY
                     DADGELAHYYRFRQLQLGRYYQVGDGPDAPSGPPLSISWDDVYKVKVSARLADFPAGSE
                     LARVARDFNAEYGAFLALLTRAFNGQPGLLQDAVCDMFRLRDGFNRLVRNPLPGGGGLH
                     AAPTFEIPTAVGADPEASQSAGETARAVTR"
     gene            11192..11743
                     /locus_tag="M878_RS57055"
                     /old_locus_tag="M878_07455"
     CDS             11192..11743
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS57055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_07455"
                     /product="hypothetical protein"
                     /protein_id="WP_023545482.1"
                     /transl_table=11
                     /translation="MTAPPSEEYEEFEEFEEFLRLSVDLTAFEETELLGTGLARRYLAK
                     VRAACGDEIVTALLDAHRAARADAAGDAGRLDRIPLDRALLDRALRHRIFSDDRLGPVA
                     RNVIKLWYAGMWYALPPEWTDRYGAHAAGETSTVTAASYQEGLLWRAIGANPPGAKGPG
                     YGSWAQPPRIEDRYLKGATK"
     gene            11740..12654
                     /gene="iolE"
                     /locus_tag="M878_RS57060"
                     /old_locus_tag="M878_07460"
     CDS             11740..12654
                     /EC_number="4.2.1.44"
                     /GO_function="GO:0050114 - myo-inosose-2 dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="iolE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010473651.1"
                     /locus_tag="M878_RS57060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07460"
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="WP_031224389.1"
                     /transl_table=11
                     /translation="MTGLADRLGPDKVKLGVCCTLWWNDDFPTIDAGISFGQAASEMAL
                     AGFQGCSIGHKYPSDAAVLKAALDLRGLRVSEPWTSTYFTISKMRQKTIAAFEETLAHV
                     RALGGTELVVAEFGASSHLLPVDVFANRPIFTDAQWDALTSGLHELGKIANSAGMKLSY
                     HHHMGTGVMTRADVDRLMASTDPALVHLLLDTAHIAFAGDDPLDMARAYADRIGHVHLK
                     SIRPEVVSRVREEGLSFQEGVELGVFTVPGDGAIDFRPILEVLADADYQGWLVVEAEQD
                     PNKAIPLEYAKKARAYLADVLGW"
     misc_feature    12670..12681
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            12674..13708
                     /locus_tag="M878_RS57065"
                     /old_locus_tag="M878_07465"
     CDS             12674..13708
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013429.4"
                     /locus_tag="M878_RS57065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07465"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_023545484.1"
                     /transl_table=11
                     /translation="MNATFKRDVFFSFFMFTADLRPQDSRYTAVLINHLKALTDMGYDG
                     FDLHIASQPATVDHKLETDSYVALKKAFDQAGLKDVKFTTNVGTTRTFDPTSPYEEQRR
                     QALSYLKSRVDITRVLGGDSIMSGPFLYPYGVFPVTDADEPIWSDALQDWMESRYRAAR
                     SVFEDLAEYAAAREVKLAIEPVKSWETPPPNMVSEALDFLDGLDHSQAGVTIDTAQVVM
                     ESQGPSVFKDNVAKAARQDRLHYVHISAPDRGAVKDSWIPWDIILNEIEPVYRGPYLVE
                     VFNAIPPFVNSMRMARRRFWRPGEDDPVPHVDSAYDVARAALEELREQIIIPSARVPRK
                     GPAC"
     misc_feature    complement(12675..12689)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.75"
                     /tool="antismash"
     misc_feature    12731..12733
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13714..14529
                     /locus_tag="M878_RS57070"
                     /old_locus_tag="M878_07470"
     CDS             13714..14529
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012955.4"
                     /locus_tag="M878_RS57070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07470"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_209445502.1"
                     /transl_table=11
                     /translation="MSDPIIMVVKQTGDVRIHTFVSSFAYSNIANATHIIETRNQLVLV
                     DGQFLVPYARAFRDYADSLGKPIERLYLSHRHPDHWFGLGTAFSDIPIYALPETMSFIQ
                     EHGEASRSDHWKLGDLAPDRIVVPKQAVSPGTETIDGVRYLFDRVTETEIDFHLTIRLP
                     DLGVYFTQDLLYSGTHLYLTQHMDHWIQVLQEMLLSDYDLFMPGHGLPADKNEVARNIE
                     YLSAARQAIGNGLAGDAFKGFMLQRYPERKCPGIFDIYMPRLFGGASDY"
     gene            14548..16203
                     /locus_tag="M878_RS57075"
                     /old_locus_tag="M878_07475"
     CDS             14548..16203
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014794.4"
                     /locus_tag="M878_RS57075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07475"
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="WP_023545486.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.1e-32, bitscore:
                     110.5, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-24, bitscore:
                     85.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDGCTVGQYLIDRLRQLGLEHLFSIAGDYSIEWLNRYVTPSSIE
                     IIEEVNEVNAGYAADGYARLKGIGALCVTYSAGALCAVNAVAGAYVEKVPLVLINGTPS
                     IKKTITFEQTGFSAHHFISGRETDLQSFEHITVAAVRVDNPDLAPALIDYALTQCISER
                     RPIYIELLQDMVDLQCEPPRGVLKPARILSDETSLEQSVERICARLESAENPLIWVGVE
                     IDRFGLQEKAMSLIQQLNIPFVTELLSKAVLSEDDALFVGVLDGQASSAAVTDLATTSD
                     FVLALGVWLTDINSLGWEPDYDKTAFASFDAVKFGTYFGGQVALEHLIEGILAQKIAPK
                     VRKLPEKPARKAPTVGSSDVITYQGFYNFIQQYIDRKTIVSSDASMNYFGSLLLDVPRP
                     GGFIVQSSYSSIGYSAPAATGICLAKSPDQRVMVFTGDGGFQMTAQCLSTQTRFKLNPI
                     IFVIDNGVYAVEQWLADASVFHADKPFYKPCVLHRWNYSMLSEVFGCRGWEVGTYGELT
                     DAVTGALKNSNSPSIIQVRVPDKSIPENAKWKTQ"
     misc_feature    complement(16214..16227)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     gene            16223..16531
                     /locus_tag="M878_RS57080"
                     /old_locus_tag="M878_07480"
     CDS             16223..16531
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02118.1"
                     /locus_tag="M878_RS57080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07480"
                     /product="EthD family reductase"
                     /protein_id="WP_023545487.1"
                     /transl_table=11
                     /translation="MPTKITAIFENPKSPEAFEAGHHEQIALAKKIPGVQRIESAKVWP
                     KEDGSATPAYRVLDMYFTDYDAASRAVTTEEASAFVAKVFELATGGVRLLFTDVEEV"
     gene            16589..>16719
                     /locus_tag="M878_RS96155"
                     /old_locus_tag="M878_07485"
                     /pseudo=""
     CDS             16589..>16719
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009719271.1"
                     /locus_tag="M878_RS96155"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="M878_07485"
                     /product="integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLLRLAHLAATNARSLLRLLPTSDRDKDIEILACGTNCSYCNA"
     gene            complement(16871..17851)
                     /gene="sbnA"
                     /locus_tag="M878_RS57085"
                     /old_locus_tag="M878_07490"
     CDS             complement(16871..17851)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173718.1"
                     /locus_tag="M878_RS57085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07490"
                     /product="2,3-diaminopropionate biosynthesis protein SbnA"
                     /protein_id="WP_023545489.1"
                     /sec_met_domain="PALP (E-value: 9.2e-48, bitscore: 162.1,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVISAPYDFNQGDLFIDLESICGHLLYLKCEAFNFAGSIKLKAA
                     KRMVESAERDGILGPDSVLVESSSGNLGVALGMIAASKGYRFLCVTDSRCNLSTRLLME
                     ALGNEVHIVADQDSNGGFLGTRIEYVRALCASDDRYVWLSQYTNEGNWWAHYCTTGPEI
                     ARQFPELDVLFVGAGTTGTLMGCARYFRQWHRPVRIVAVDSVGSVAFGGEPGRRMIPGL
                     GMSMRPPLLDESCVDEVIRVEERDTIRMCRRMARRGFLFGGSTGTVVSAATDWLARHDT
                     RAVTAVAIAPDLGERYLDTVYQTNWLQDLYGDQVLDAADTAQADT"
     gene            complement(17888..18958)
                     /gene="sbnB"
                     /locus_tag="M878_RS57090"
                     /old_locus_tag="M878_07495"
     CDS             complement(17888..18958)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675612.1"
                     /locus_tag="M878_RS57090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07495"
                     /product="2,3-diaminopropionate biosynthesis protein SbnB"
                     /protein_id="WP_023545490.1"
                     /transl_table=11
                     /translation="MTDVLSTPGRPAMPERASVPTFAVITGEQVQQALSGREKQLVELV
                     EAAYRLHDAGDTVNPPSYFLRFPDRPTARIIALPASIGGQAHVDGLKWISSFPQNVSAG
                     LPRASAVLILNDHDTGYPFACLESSIISATRTAASAALAADRLSRGRPRPTRVGFFGTG
                     LIARYIHTFLNGTGWAFEAVGVHDVSADSATGFRGYLRQAGATAPITVHDSAEDLVRAS
                     DLVVFATISGRPHVSDPAWFSHNPLVLHVSLRDLAPEVLLGSANFVDDVEHCLKADTSP
                     HLAEQFTGNRDFLNGTLSDVMAGRAAPPADRPVVFSPFGLGVLDLAVGKYVYDEVSRAG
                     NLRLIDDFFHELRRYG"
     gene            complement(18955..19959)
                     /locus_tag="M878_RS57095"
                     /old_locus_tag="M878_07500"
     CDS             complement(18955..19959)
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0051213 - dioxygenase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: TauD (26-314). E-value: 1.5e-46. Score:
                     151.2. Matches aSDomain:
                     nrpspksdomains_M878_RS57095_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546321.1"
                     /locus_tag="M878_RS57095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07500"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_023545491.1"
                     /sec_met_domain="TauD (E-value: 2.3e-44, bitscore: 151.2,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFSSLASPLDVELQPDRPALLHVDPLDDAPSWVAEHREALRAQV
                     TGHGALVVRGLGLRDIDQVSAVFSHMADGLIAERESFAPRQAHRPGLYASTTWPANQPM
                     CMHHELSYPLQVPGLMLFACLTAPEQGGATAVADAEQVLRALPTGLTERFEREGWVLTR
                     TYNDEIGASLAESFGTGDRAEIERYCRANAIDFTWEPDGTLRTEQRRSAVVRHPLTGRR
                     CWFNQIAFLNEWTLAPEVREYLVDVYGEDRLPFNTRYGDGSPIDEAVVQLINSTYEAHT
                     RREPWRAGDLLLVDNIRTAHSREAFTGEREVLVGMAEPLRPADRRATPEASER"
     aSDomain        complement(19018..19881)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS57095_TauD.1"
                     /evalue="1.50E-46"
                     /label="M878_RS57095_TauD.1"
                     /locus_tag="M878_RS57095"
                     /protein_end="314"
                     /protein_start="26"
                     /score="151.2"
                     /tool="antismash"
                     /translation="LDDAPSWVAEHREALRAQVTGHGALVVRGLGLRDIDQVSAVFSHM
                     ADGLIAERESFAPRQAHRPGLYASTTWPANQPMCMHHELSYPLQVPGLMLFACLTAPEQ
                     GGATAVADAEQVLRALPTGLTERFEREGWVLTRTYNDEIGASLAESFGTGDRAEIERYC
                     RANAIDFTWEPDGTLRTEQRRSAVVRHPLTGRRCWFNQIAFLNEWTLAPEVREYLVDVY
                     GEDRLPFNTRYGDGSPIDEAVVQLINSTYEAHTRREPWRAGDLLLVDNIRTAHSREAFT
                     GEREVLV"
     gene            complement(20001..23252)
                     /locus_tag="M878_RS57100"
                     /old_locus_tag="M878_07505"
     CDS             complement(20001..23252)
                     /NRPS_PKS="Domain: AMP-binding (243-645). E-value: 2.3e-94.
                     Score: 308.2. Matches aSDomain:
                     nrpspksdomains_M878_RS57100_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (754-821). E-value: 6e-18. Score:
                     56.8. Matches aSDomain: nrpspksdomains_M878_RS57100_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (841-1074). E-value:
                     1.6e-20. Score: 66.5. Matches aSDomain:
                     nrpspksdomains_M878_RS57100_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675614.1"
                     /locus_tag="M878_RS57100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07505"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_023545492.1"
                     /sec_met_domain="Condensation (E-value: 4.5e-05, bitscore:
                     21.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-101, bitscore:
                     339.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.2e-08, bitscore:
                     33.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 1e-16, bitscore:
                     60.9, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTGVDTDREFWSRVLTAGGVTTVPRWVREPVPGADEHEMPVPED
                     VTEAVRELVRHRGVPVSALLLAVHVKVLGVLSGEPEVVTGYTTGVRGEPLPCRSAIPPG
                     SWQALLSAAEQAEAEVLAHREFPVEKLRRELGLTEPPYEAVFGPIGADEAHADDGVLQV
                     RWSDRGGRLTLRLRYRTDVLDTAAAARIGGYHLTALRLMTADPDADHTRQSLLSADEVQ
                     EQLEGLAGPRRPLPDARAHELFEQRVRAHPQAVAAVHGEQECTYGELNRRANRLARALV
                     TRGLRREDVVAVVTERNLDWLAATLAVFKAGGAYLPIEPHFPAGRIAATLSRAGCRLVL
                     TESGSTHTLDQALGTLPGVEKLPVDTAYAEPHAADDLGVQVDPGQLAYIYFTSGSTGEP
                     KGAMCEHAGMLNHLYAKIDDLVIGEGCVVAQTAPQCFDISLWQFMAPLLVGGRTLLVEQ
                     DVITDVERFVDTLERRRVGVTQLVPSYLEVVVSCLEQNPRALPDLRCVSVTGEALKREL
                     VQRWFAVQPGIELLNAYGLTETSDDTNHEVLQGVPDRVLLGRPVNNVRVYVVDERLSLV
                     PLGAPGLIAFSGVCVGRGYVNDPERTREAYRTDPYRPGERLYLGGDWGRWHPGAKLEFL
                     GRRDSQVKIRGFRIEIGEIENSLLRVDGVRDAAVVVSERSGGSKQLIAFYSGRQRQPEV
                     LREALGAVLPAYMVPSAFHWQDSLPLTANSKIDRKALTGLAEESAPERQAGDHAGLLSP
                     NERKVAAAWAELLGVPEAQIGRRDHFFDSGGTSLTAVRLSLALDRSVSLKDITRHPVLA
                     DLAALLDGTARQRPELLLPLSDGSGVPQHALVCFPHAGGNAVNYQPMASALAGGDMEVL
                     AVDLPGHNLDAHPEPFATIEQVAEQVTDEITARGLTRVMLWGHSSGVAHAMETARRLMQ
                     RRVRVTRVFLGAQLLGTSADRHTAIGDLASRSDAEIAARLTADGGYRELTELNERHAEH
                     LGAAYRHDCVCAHRYFCEALEEPPPVRLSAPVTVVVAADDPHTAGYADRHRDWLLLAEH
                     VDLHELADGGHYFLRTRPSQAAQAVLSTLVPLASC"
     aSDomain        complement(20031..20729)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS57100_Thioesterase.1"
                     /evalue="1.60E-20"
                     /label="M878_RS57100_Thioesterase.1"
                     /locus_tag="M878_RS57100"
                     /protein_end="1074"
                     /protein_start="841"
                     /score="66.5"
                     /tool="antismash"
                     /translation="ALVCFPHAGGNAVNYQPMASALAGGDMEVLAVDLPGHNLDAHPEP
                     FATIEQVAEQVTDEITARGLTRVMLWGHSSGVAHAMETARRLMQRRVRVTRVFLGAQLL
                     GTSADRHTAIGDLASRSDAEIAARLTADGGYRELTELNERHAEHLGAAYRHDCVCAHRY
                     FCEALEEPPPVRLSAPVTVVVAADDPHTAGYADRHRDWLLLAEHVDLHELADGGHYFLR
                     TRPSQAAQAVL"
     aSModule        complement(20031..22523)
                     /complete
                     /domains="nrpspksdomains_M878_RS57100_AMP-binding.1"
                     /domains="nrpspksdomains_M878_RS57100_PCP.1"
                     /domains="nrpspksdomains_M878_RS57100_Thioesterase.1"
                     /final_module
                     /locus_tags="M878_RS57100"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(20790..20990)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS57100_PCP.1"
                     /evalue="6.00E-18"
                     /label="M878_RS57100_PCP.1"
                     /locus_tag="M878_RS57100"
                     /protein_end="821"
                     /protein_start="754"
                     /score="56.8"
                     /tool="antismash"
                     /translation="ERKVAAAWAELLGVPEAQIGRRDHFFDSGGTSLTAVRLSLALDRS
                     VSLKDITRHPVLADLAALLDGT"
     CDS_motif       complement(21288..21353)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS57100_0005"
                     /evalue="2.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="M878_RS57100"
                     /protein_end="655"
                     /protein_start="633"
                     /score="35.8"
                     /tool="antismash"
                     /translation="FLGRRDSQVKIRGFRIEIGEIE"
     aSDomain        complement(21318..22523)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS57100_AMP-binding.1"
                     /evalue="2.30E-94"
                     /label="M878_RS57100_AMP-binding.1"
                     /locus_tag="M878_RS57100"
                     /protein_end="645"
                     /protein_start="243"
                     /score="308.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEQRVRAHPQAVAAVHGEQECTYGELNRRANRLARALVTRGLRRE
                     DVVAVVTERNLDWLAATLAVFKAGGAYLPIEPHFPAGRIAATLSRAGCRLVLTESGSTH
                     TLDQALGTLPGVEKLPVDTAYAEPHAADDLGVQVDPGQLAYIYFTSGSTGEPKGAMCEH
                     AGMLNHLYAKIDDLVIGEGCVVAQTAPQCFDISLWQFMAPLLVGGRTLLVEQDVITDVE
                     RFVDTLERRRVGVTQLVPSYLEVVVSCLEQNPRALPDLRCVSVTGEALKRELVQRWFAV
                     QPGIELLNAYGLTETSDDTNHEVLQGVPDRVLLGRPVNNVRVYVVDERLSLVPLGAPGL
                     IAFSGVCVGRGYVNDPERTREAYRTDPYRPGERLYLGGDWGRWHPGAKLEFLGRRDSQV
                     KIR"
     CDS_motif       complement(21438..21524)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS57100_0004"
                     /evalue="8.00E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="M878_RS57100"
                     /protein_end="605"
                     /protein_start="576"
                     /score="27.8"
                     /tool="antismash"
                     /translation="PLGAPGLIAFSGVCVGRGYVNDPERTREA"
     CDS_motif       complement(22035..22094)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS57100_0003"
                     /evalue="4.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="M878_RS57100"
                     /protein_end="406"
                     /protein_start="386"
                     /score="28.3"
                     /tool="antismash"
                     /translation="AYIYFTSGSTGEPKGAMCEH"
     CDS_motif       complement(22299..22337)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS57100_0002"
                     /evalue="1.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="M878_RS57100"
                     /protein_end="318"
                     /protein_start="305"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LAVFKAGGAYLPI"
     CDS_motif       complement(22809..22895)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M878_RS57100_0001"
                     /evalue="5.60E-05"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="M878_RS57100"
                     /protein_end="148"
                     /protein_start="119"
                     /score="15.8"
                     /tool="antismash"
                     /translation="VLAHREFPVEKLRRELGLTEPPYEAVFGP"
     gene            complement(23266..25851)
                     /locus_tag="M878_RS57105"
                     /old_locus_tag="M878_07510"
     CDS             complement(23266..25851)
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: PCP (29-99). E-value: 1.5e-14. Score:
                     45.9. Matches aSDomain: nrpspksdomains_M878_RS57105_PCP.1"
                     /NRPS_PKS="Domain: TIGR02353 (132-833). E-value: 4.4e-261.
                     Score: 859.9. Matches aSDomain:
                     nrpspksdomains_M878_RS57105_TIGR02353.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546323.1"
                     /locus_tag="M878_RS57105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07510"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_023545493.1"
                     /sec_met_domain="PP-binding (E-value: 1.6e-11, bitscore:
                     43.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 6.5e-259, bitscore:
                     859.9, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEQSSEVVSGPDEPAVALSDTGPTGAETERKLAEALADLLGAER
                     VPVDSHFFADLGANSLVMAQFCARVRKTADLPSPSMRDIYQHPTIQGLAAALGEATPAP
                     VDPVAAPSAPAPVPSSASGPRGNPRSHVLCGTLQLLVFLGYSLVSGFITAAGYEWIATG
                     SGVADIYLRSLLFGGIGFVALCAFPVVAKWLLIGRWRPGEFPVWSMAYLRFWLVKVLLH
                     ANPMVFLTGTPLYVLYLRALGARIGKGVAILSHSVPVCTDLLTIGAGTVIRKDSFFLGY
                     RAHAGRIQTGRITLGADVFIGEKTVLDIDTSMGHRAQLGHSSALYRGQAVPDGEHWHGS
                     PAQPTQIDYVRVPPAGCRTARRAWFGLGTLVQLFFLYIPLAVGGAYMLFTEVPAIGKRL
                     DPQTAALSRSELLSDALVLSLVLFFGCVVLGLVALYTVPRVVGLVVKPDKVYPLYGFHY
                     ALHRATARMTNIKFFAWLFGDSSYIVHYLRGLGYDLSRVEQTGSNFGTEVQHETPLLVS
                     VGSGTMVADGLSLINADFSSTSFRLSRVSIGPHSFLGNNIAYPAGGRTGDNCLLATKVM
                     VPLDGEVREGVGLLGSPCFEIPRSVDRDTRFDHLRTGDTLRRRLAAKNRYNLRSMVLML
                     LVRWLHTFALTLFGLASVDLYGVVGHVVIAGYLVITLAFSTAYFILVERCIASFRPLRP
                     RLCSIYDPYFWWHERLWKVPDHFLEIFNGTPFKTLVWRLLGVRIGRRVFDDGCYLTERT
                     LATIGDECTLNAGSKIQCHSQEDGTFKSDGTVLGTGCTLGVGAHVHYGVTMGDGSVLAP
                     DSFLMKGEEVPRKAHWGGNPAVHMPESGIRSIDVGRATSSADAAAATAS"
     aSDomain        complement(23353..25455)
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS57105_TIGR02353.1"
                     /evalue="4.40E-261"
                     /label="M878_RS57105_TIGR02353.1"
                     /locus_tag="M878_RS57105"
                     /protein_end="833"
                     /protein_start="132"
                     /score="859.9"
                     /tool="antismash"
                     /translation="LCGTLQLLVFLGYSLVSGFITAAGYEWIATGSGVADIYLRSLLFG
                     GIGFVALCAFPVVAKWLLIGRWRPGEFPVWSMAYLRFWLVKVLLHANPMVFLTGTPLYV
                     LYLRALGARIGKGVAILSHSVPVCTDLLTIGAGTVIRKDSFFLGYRAHAGRIQTGRITL
                     GADVFIGEKTVLDIDTSMGHRAQLGHSSALYRGQAVPDGEHWHGSPAQPTQIDYVRVPP
                     AGCRTARRAWFGLGTLVQLFFLYIPLAVGGAYMLFTEVPAIGKRLDPQTAALSRSELLS
                     DALVLSLVLFFGCVVLGLVALYTVPRVVGLVVKPDKVYPLYGFHYALHRATARMTNIKF
                     FAWLFGDSSYIVHYLRGLGYDLSRVEQTGSNFGTEVQHETPLLVSVGSGTMVADGLSLI
                     NADFSSTSFRLSRVSIGPHSFLGNNIAYPAGGRTGDNCLLATKVMVPLDGEVREGVGLL
                     GSPCFEIPRSVDRDTRFDHLRTGDTLRRRLAAKNRYNLRSMVLMLLVRWLHTFALTLFG
                     LASVDLYGVVGHVVIAGYLVITLAFSTAYFILVERCIASFRPLRPRLCSIYDPYFWWHE
                     RLWKVPDHFLEIFNGTPFKTLVWRLLGVRIGRRVFDDGCYLTERTLATIGDECTLNAGS
                     KIQCHSQEDGTFKSDGTVLGTGCTLGVGAHVHYGVTMGDGSVLAPDSFLMKGEEVPRKA
                     HWGGNPA"
     aSModule        complement(23353..25764)
                     /domains="nrpspksdomains_M878_RS57105_PCP.1"
                     /domains="nrpspksdomains_M878_RS57105_TIGR02353.1"
                     /incomplete
                     /locus_tags="M878_RS57105"
                     /tool="antismash"
                     /type="unknown"
     misc_feature    complement(25435..25437)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(25555..25764)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS57105_PCP.1"
                     /evalue="1.50E-14"
                     /label="M878_RS57105_PCP.1"
                     /locus_tag="M878_RS57105"
                     /protein_end="99"
                     /protein_start="29"
                     /score="45.9"
                     /tool="antismash"
                     /translation="ERKLAEALADLLGAERVPVDSHFFADLGANSLVMAQFCARVRKTA
                     DLPSPSMRDIYQHPTIQGLAAALGE"
     misc_feature    25871..25884
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            26243..26506
                     /locus_tag="M878_RS000000101005"
     CDS             26243..26506
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039405.3"
                     /locus_tag="M878_RS000000101005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6308 family protein"
                     /protein_id="WP_280923683.1"
                     /transl_table=11
                     /translation="MDEAGQAPRGACTRTGARARASRPCSASWSTTWAALAAALRADNG
                     TFYDQLVHFRRKAGIGEDIGIPRVFDVAAWMRQGRPVEASTN"
     misc_feature    26708..26717
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            26986..27378
                     /locus_tag="M878_RS57110"
                     /old_locus_tag="M878_07520"
     CDS             26986..27378
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS57110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_07520"
                     /product="hypothetical protein"
                     /protein_id="WP_023545495.1"
                     /transl_table=11
                     /translation="MAGAALAIADSPCLWATVGRSMVVAFGAFSVADVALPMRCAPSLE
                     PGCPADNRLLAHHDQRPGPFRPVRPDDGVHSRGTPRRLAPSAGPALGAPAPAIVHDRGR
                     LFHGPYFGHPGGHGIAQPIHLVTVAV"
     gene            27903..30002
                     /locus_tag="M878_RS57115"
                     /old_locus_tag="M878_07525"
     CDS             27903..30002
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014628399.1"
                     /locus_tag="M878_RS57115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07525"
                     /product="hypothetical protein"
                     /protein_id="WP_023545496.1"
                     /transl_table=11
                     /translation="MAAVGAIAALAGTLVVSVDTAGATNAPPAYTSAIPDTAPRLPAAA
                     PHWTALAAKRFWTAQRMAEAKPLPDARPRTAGKAAHPTLQGLVKPPVTGGLNAQDLREV
                     PMDATPTGTAGPTDTPTDTSTPDPSATATDTPTAAPTDTSSASPSTSPSASDSASPTAS
                     PSPSPTSTGGTGPVSSYFGGLPMVGRMYMQTSSGSYFCTASVINSPHHNIVLTAGHCMD
                     GRAGGGSLAFVPEWTAANPQPYGIFPVATDSEGRSRVWIDPRYYDRGHVQGASWDMAFA
                     QVGARSDGKQVQDVVGGNNLATGRGYAFPSIRLVGYPGTATQPLTCDNNTTQYTPTDGT
                     PGSYLQIACNGFASGTSGSPFLENFDPTTGTGDVVGSIGGWDTGGPTDDVSYSSSYGSD
                     VQNLYKAAVAGTAPARPNVLPGASTLTHATLVTSGSFTPSPSPDPDKGDLIVCWSDGEL
                     TLYRGGGNGRFDKEIRLVAANTTWTKAVSITGGDFTGTDTYDLLVRWSDGSLTLFPDVD
                     ARGLHSQITLVKPGTLWQHEVAMTAGRYTTDDHWPDDLIVRWSDGETTLYKNINSTGLH
                     SEVRLNPANSTWTHATSLTSADLAGTNESDLVVRWSDGELTLYPDINQYGFHGEVRLRA
                     PSTLWTHATLTASGNFTSTDTRPNDYLVRWSDGQLSMYQDSGNSLGTEAVLATASGSSL
                     PYYRR"
     gene            30356..>30722
                     /locus_tag="M878_RS96160"
                     /pseudo=""
     CDS             30356..>30722
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008408956.1"
                     /locus_tag="M878_RS96160"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="ArsI/CadI family heavy metal resistance
                     metalloenzyme"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPILREYEHLDASVAFCSKLFGTEPSKLRDGCANFAITEPPAQAR
                     HDRRHGR"
     gene            30720..>31286
                     /locus_tag="M878_RS47235"
                     /pseudo=""
     CDS             30720..>31286
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019121.4"
                     /locus_tag="M878_RS47235"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ATP-grasp domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.6e-29,
                     bitscore: 101.8, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 3.3e-08, bitscore:
                     32.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEPAVASGCSPTPGRHVWTGGPATWNGRPVMVKPPFGGSSVGMSL
                     VRDPADLPGALADAADDERAAVLVEEYVSGLPLTVGLLELPGGSAIVFPPLATEATEAE
                     FYDADTKLDVDSKGTVTVRAAELAPDVLDKITADVRTLWDGIGLRGSARIDFILTEDGQ
                     PYVLEVNSTPGMSRDSNFAVGAAMVG"
     gene            31357..31653
                     /locus_tag="M878_RS99575"
     CDS             31357..31653
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999435.1"
                     /locus_tag="M878_RS99575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_051430069.1"
                     /transl_table=11
                     /translation="MEHFTRGSRAWRPTWECFAAESGVDLVVAVGGDLAKQLALAAGAA
                     GVPEIALVGDNATAASYLGSVLRPGDVVLVKASRGGQLWQIAQALTGQPVTGL"
     misc_feature    31820..31835
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     misc_feature    31884..31897
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.51"
                     /tool="antismash"
     misc_feature    31886..31903
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     gene            31926..32825
                     /locus_tag="M878_RS57125"
                     /old_locus_tag="M878_07545"
     CDS             31926..32825
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656098.1"
                     /locus_tag="M878_RS57125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07545"
                     /product="hypothetical protein"
                     /protein_id="WP_023545500.1"
                     /transl_table=11
                     /translation="MSMLLITGSYRILGDRPDGDTVHFTPRDPGFWCEVPGQHRVKRDE
                     NGGASLRLDGIDATETHYKGVGPEFVHQPLRLGAHAARDELLSWLGFDDVVQDPEEKVT
                     ASAPETVPGYILTSGADVYGRCVALIGRGDPPEIGNPPKPAKSGDRIDVTVDMLHRTAN
                     HHLLSRGLVYPTFYSNLPRELRANMTTTTQEARAAQVPGGVWSYDVTTSGAKIDSLASL
                     TDELVIVPKLFRRLADYIRLFGPSLACLPSYLAGGADEFYVPGQRDSIVGLQRVVEVTN
                     GNTLRMTRPIEDLVFVEK"
     gene            32846..33253
                     /locus_tag="M878_RS57130"
                     /old_locus_tag="M878_07550"
     CDS             32846..33253
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023737.4"
                     /locus_tag="M878_RS57130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07550"
                     /product="sugar dehydrogenase complex small subunit"
                     /protein_id="WP_023545501.1"
                     /transl_table=11
                     /translation="MSDATDFRALSELLTGEGRLNAQRADDYRVRLTAAFPADVPRLLD
                     AYRTVTSQDDPGKALVDAVNADPALARLTRETITVWYTAQFTRPDGKPDAPGTPAQYQD
                     GLIWRVIEAHPPSFAPQPPAPSGYGYWTDHP"
     gene            33273..34970
                     /locus_tag="M878_RS57135"
                     /old_locus_tag="M878_07555"
     CDS             33273..34970
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017050.4"
                     /locus_tag="M878_RS57135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07555"
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_023545502.1"
                     /transl_table=11
                     /translation="MNPQYDVVIVGGGAAGALTACRIKSAKPDARILLLDAGNNGTAKP
                     DRDAFVAAYQTAAIKNVPSPYAGLDNNRLGYAPSSDGAPDPVAMNRYYVETGPDLYESG
                     FQRMLGGSTWAWRGNTPRFLPNDFQLKTNYGVGADWPIAYADLEPYYVQAEAELGVSGN
                     DDEWVGLTPRSAPYPMPGMAPSYGDELVRAALADIGPIDGVPVTVVTTPQARNSEEYRD
                     RSACQGNSSCIPVCPSGAKYDAGFHIGLARDRLGVEIRTACVVTRLLPRPGNLAPTVVF
                     RDWTTADKAEQQVDAQHVVVAVNAIETPKLWLLSGLDNRSDQVGRNLMDHLANEIVGLF
                     GQPVFPFRGPQSALGIDTFRDGDFRRNNGAFRMTIGNDGWGRTEPPAVALAHFMWDDAN
                     KRIKLTGQPLQQAIRDRVTRQLRISFSTEQLPDPANRVTLSDERDALDIPRPKIAYRID
                     DYSKRALAYGHSVARRMWQHLEDTAGATEVSPLQPDLRFLGAGHLMGTMRMGTGPSASV
                     VDPTGQSHAHRGVWVVGSSVFPTCGTANPTLTLSALTLRTADALAATL"
     gene            35038..35706
                     /locus_tag="M878_RS57140"
                     /old_locus_tag="M878_07560"
     CDS             35038..35706
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012521.4"
                     /locus_tag="M878_RS57140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07560"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_023545503.1"
                     /transl_table=11
                     /translation="MTITTRLVLARHGEAQCNVDGLVGGPLTCTGLTVRGREQTRRLAT
                     RLTAEHRTGPGFDVLYAGPRARLQESGRILATALDLPLLTDPGLDGPRHGQADGRPWRD
                     VEAEFQGRPAASPDLPWSPGSDTWNGYLLRAGRALTALLERHAGQSILLAGHGETIHAA
                     CHLLLELSPSTSSRIDFGTEHACLTRFHLHHDPYGRRFWTLAALNDTAHLQQPVADRDS
                     "
     gene            complement(35715..36500)
                     /gene="fetB"
                     /locus_tag="M878_RS57145"
                     /old_locus_tag="M878_07565"
     CDS             complement(35715..36500)
                     /codon_start=1
                     /gene="fetB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539333.1"
                     /locus_tag="M878_RS57145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07565"
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="WP_023545504.1"
                     /transl_table=11
                     /translation="MNPAVPTWAGVAASAALIALTIAVAWHGRLRLGRDITVAAVRAAL
                     QLAAVGALLLLVFRHTGLTGAIGWLGIMVLIAGQVAARRTPALPKALPTATAAITIGTA
                     ATMGTLLALGVIATQARVVIPVGGMVVSGAMQATALALTRLHDEVRTARPAIEARLSLG
                     LAATDAFAPHQRTIVRTALIPALDSTKTVGVISLPGAMTGLILAGVDPFTAIRYQIVVM
                     YMLLAAAALAALIAVRLSERALFDDAHRLRPLAAQSAGS"
     gene            complement(36497..37198)
                     /locus_tag="M878_RS57150"
                     /old_locus_tag="M878_07570"
     CDS             complement(36497..37198)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539332.1"
                     /locus_tag="M878_RS57150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07570"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_023545505.1"
                     /transl_table=11
                     /translation="MVTVGEEPIQTTAFALDQVTVRRGDATLLEEITCAIPASACTALV
                     GPSGAGKTTLLRLLNRLEEPTTGTVTFQDRPLPAWNVLTLRRRVTLVGQQPVLLTDTVM
                     DDLRVGRPDLDRHEAATLLDRAHLPAAYLDRPTTNLSGGEAQRVCLARALAVTPQALLL
                     DEPTSALDAVGTAAVEGVVRDLVADGLTVVLVSHNTAQARRVSDHVLVLDHGHLVDQGE
                     AHRVDYLKEYA"
     gene            complement(37240..38283)
                     /locus_tag="M878_RS57155"
                     /old_locus_tag="M878_07575"
     CDS             complement(37240..38283)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009078956.1"
                     /locus_tag="M878_RS57155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07575"
                     /product="YncE family protein"
                     /protein_id="WP_023545506.1"
                     /transl_table=11
                     /translation="MIRHLSPRTLLVLAAGLVLAAIAAVAGVLLTRGGDKPPKEALPLR
                     QVKEISLPGDSSRFDYASLDPGRGLLFIAHLGASQVIEVDTHADKVVRTIYDLPGVHGV
                     LVVPALHRVYATASDANQVAAIDETTGKVLHRSPTGGTPDGLAYDPVHNRVWTTNESGG
                     SETVVDAGSGAVRGTVPLGGEAGNVAYAPITRQMLVDVQTRNELAVIDPTTLHITRRVP
                     LPGCDHDHGLTLDSADRLAFVACDGNARLLTLDLATWRVTGTDEVGQDPDVLAYDAPAR
                     HLYVAAESGWVTTADTHDRHLTVTGRAHLADGAHVVAVDPTTHLSYYPVPHGSGGHPAL
                     LVYRPGT"
     gene            complement(38377..38742)
                     /locus_tag="M878_RS57160"
                     /old_locus_tag="M878_07580"
     CDS             complement(38377..38742)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010038912.1"
                     /locus_tag="M878_RS57160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07580"
                     /product="hypothetical protein"
                     /protein_id="WP_023545507.1"
                     /transl_table=11
                     /translation="MIGWGQIDYGAALSAVVAALLIAAARGRGRDVLATGALAAAIGPL
                     AWNAILRAAHGDQFFTDAPVTVFPVSWQDTGSGVFTLAAASLGYGLDPLAAQPARTSIR
                     YALLAAVAALLVDIYLY"
     gene            complement(38739..39743)
                     /locus_tag="M878_RS57165"
                     /old_locus_tag="M878_07585"
     CDS             complement(38739..39743)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014144527.1"
                     /locus_tag="M878_RS57165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07585"
                     /product="DUF1259 domain-containing protein"
                     /protein_id="WP_023545508.1"
                     /transl_table=11
                     /translation="MSPRSLTKPAAGTAAALLLVTGAGLLTGCGTQTRSTADNAMNAAA
                     IQTDAPHGHLQQPVQTTEKDWKPVADALGRTGTLMKGTVYHIALPRKDLKVTTEGVAIK
                     PGLSLGGYANFAKYHDGTMLMGDLVVTEDELPKVTDALQAAGIEQTALHKHLLQQSPAI
                     WWTHVHAMGDPVKLAQGLKSALDATAIPPASPPPPTQPPIALDTAGIDKALGRKGTTDG
                     GIYKFTVARNQTVNDGTHVLPPALGLTTGINFQPLGGNKAAINGDFVMTAPEVQKVIQA
                     LRKGNIDIVELHNHSLTDQPRLFYLHYWATADGVTLAKALRPALEATDPAPAS"
     gene            39923..40621
                     /locus_tag="M878_RS57170"
                     /old_locus_tag="M878_07590"
     CDS             39923..40621
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179950.1"
                     /locus_tag="M878_RS57170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07590"
                     /product="response regulator transcription factor"
                     /protein_id="WP_023545509.1"
                     /transl_table=11
                     /translation="MRILVVEDEPKMRDLLQRALTEEGYAVDTAADGPQALALTDVAAY
                     DAMVLDVMLPGPDGFEVCATLRRRGIWLPVLMLTARDAVTDRVQGLDGGADDYLTKPFS
                     LDELMARLRALIRRGPVERPTVLTAGDLSLDPATRTVRRGDEEVPLTAKEYALLEALLH
                     RPGTVLTRAVLVEHCWDLGTSPGSNVVDAHIKALRDKIDRPYGTRAVETVRGAGYRIRR
                     DGGRPSTRTS"
     gene            40618..41697
                     /locus_tag="M878_RS000000101010"
                     /old_locus_tag="M878_07595"
     CDS             40618..41697
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="M878_RS000000101010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07595"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_023545510.1"
                     /transl_table=11
                     /translation="MNRIPLRIRLTAIFAAVMALVLTGAGYLTLSRFRESQAEYGAATG
                     IAHQAQQEALDDLLRELLTALPIVFVLATIGAYLLAAAALRPVERMRTQAAAVTEDTPE
                     YRLDVPPSRDEIARLATTLNDMLTRLQTALDHERLFVADASHELRTPLSLLRTEIELAL
                     RHPREATELHAALVSAHEETERLVQLAEDLLLLARTDRRDTSAGSAVPDLAPLLHRVAA
                     RLRNGSPDKSITVGCPAGLAAAVPNDRLDRAVTNLIHNAQQHGRGPVEVTVRPGEKCIR
                     IEVRDQGPGFPPDFLPHAFDRFTQADRSRATSGTGLGLAITAAIARAAGGQYGAFNHPE
                     GGAVVWITLPPLPQPPGTA"
     gene            41803..42321
                     /locus_tag="M878_RS57180"
                     /old_locus_tag="M878_07600"
     CDS             41803..42321
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994300.1"
                     /locus_tag="M878_RS57180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07600"
                     /product="Chromate resistance protein ChrB"
                     /protein_id="WP_023545511.1"
                     /transl_table=11
                     /translation="MTADRPPRDPGEWVLLSYRMPREPSTPRITLWRKLKRLGVAQLSD
                     GLVALPADARTREQLEWIADEAIEAGGTASIWIARPATHAQEHELATSMAAARAAEYQA
                     VIDHATQATGAANTAAVVRRLRAELRRIGRRDFFPPLERDRAHAAVHALTDEPGASVPK
                     AASHREKNA"
     gene            42318..42749
                     /locus_tag="M878_RS57185"
                     /old_locus_tag="M878_07605"
     CDS             42318..42749
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021357.4"
                     /locus_tag="M878_RS57185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_07605"
                     /product="chromate resistance protein ChrB
                     domain-containing protein"
                     /protein_id="WP_023545512.1"
                     /transl_table=11
                     /translation="MKWATRAGIHIDRAACAWLIRRHVDKEAEFVFVTDPAEVPDDATP
                     FDMRGVQLGHHGGDCSFETILRHYELTDPVLWKLAEIVHEADLDDERYDAPEAPGVDVV
                     LRGLSMICDDQRILELTGPLFDGLYEYHHRGMLLGREPS"
     gene            42772..43146
                     /locus_tag="M878_RS57190"
                     /old_locus_tag="M878_07610"
     CDS             42772..43146
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS57190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M878_07610"
                     /product="hypothetical protein"
                     /protein_id="WP_023545513.1"
                     /transl_table=11
                     /translation="MPLVIASSPEIFSTAHIGLTAAITGVLALAMAIWRLPRSAWLDMA
                     AVAVLSAASVYLWRTSANMTSLNKDGLPGFSANDWAAPILTYIFLSLYADVRIPADPRR
                     YAQARALATLASLAVNVITI"
ORIGIN
        1 cgggcggtac gcagccgtac gtgtccggcg ttcaccttgc cgagggcgtc ggcgggcagg
       61 aaggtccggc gccggccgat gcgcaggatc agcccggtga ccggcgggta ggagtccacg
      121 ccgtagagcc gggcgacgac gtcgacgacg cggcccacct cctcccccga ctggttggtg
      181 acggggccgc cgatcagccc ggccaaggag accagcgagg tgcgcaccgc cttggacgcg
      241 gtggcgcggc gctccagatg gacccggcgg tcacggaagc gggccgaggt ggacatgagc
      301 agagtgtgag cagccaaggt gaacaccccc tggccccggc atggcggggc tacgggcggc
      361 ccacggcagc acgcttcctc cccgggccgg cggcgcaggg cacgccgagc gtacgccacc
      421 acacggcctg gcgggtgggc cggtgagctt ggcggggctc agggaagaga gggctgctcc
      481 gggccgcgga aggacggcgc ggacaacacg aagaagggcc gactatggcc cggactactg
      541 tccatgtcgc ctcctcccgg tcacggccgc gcacgaggtg tcacggtcct gcggcacagg
      601 gcagcccgaa ccggccggcg ctccccaact cgtcagagct ttggcacttc acggcgtgat
      661 ccccggcgaa tccgcgggga agccacctgg ggtcacccct gtgggccggg gagacctttc
      721 gtgatccgga gcgtctctcg acgcgtggga tcagtggcct gtgtccgtga agacgcctca
      781 ccgtacgagg tgtctgttag atccgcgcca agaatacgcc cgccccgggc tgccctccca
      841 acccatgacc ggcccttgac ctgcgcacaa cagaacggag aacgaatctg ccgtttccgt
      901 ctccgtctcc cccgcccctg ccgcgagggc gcggtcgcgg cggacgcaga accagaagga
      961 ccaggcgatc aggacgacgg ccgtaccgag cacgcacagc tccggccggc cgtaggcgac
     1021 cggcatccca gcggcaccat gcgccgggcg gagcctgtcc cacgccccca actacatcca
     1081 gcacacccag atctgcaccg gctggaacga atcaccactg atgacccagc acaccgacga
     1141 ctacgccgac cgccccctct ccgagatcct ttccgatccc gccaacggca gtgcgtggct
     1201 ctaccccctc cagacctgag ggccagcaca caggcacgct gacggcccgg ccgagtgctt
     1261 cgtggccgcc gccgtcaggg atccggcagc gtttcttggc gtcgatgtgc accagttcgc
     1321 ccggccgggc acgttcgaag cggcggaccg gctggccagt ggcccagtcc tggcccgcca
     1381 gagcgggcag gcaggggccg tctgccgtca ggtcggaggg ccctggagat cagtgacggt
     1441 caactgggcc ggcgaatcga tggaatgcag gcgccacagt gacgggatgc cgtcatcggt
     1501 cgagccaggc tttctgcaat atggccccag tgcagcaaac attggggtcg gctgccactg
     1561 gcatgggtgt gggctccccc tgaggtcagg ccgtggcctc gaccagccgc ttcatgccgg
     1621 gatggtcggt gacgcagccc accaggccga gcgcccgggc cagcgccagg tcgcgctcgt
     1681 cgttgacggt ccaggccatc acgtcgatgc cggcggcgcc gcacttctcc acgatggccc
     1741 ggttcagctg gcgcagctcc acactgacca gggtggaacc gaccttctga gcacggccga
     1801 cgaaggtgtc gcggtgcgcg ctggggcctg ccaccagcac ggtgcgggcc cgcggcagca
     1861 ggttgtggat ctcgatcagc gccacgtcgt ggaacgacag caccgatacc cggtccagca
     1921 ggtcgcggtc ggtgagcacc ttggccagcg accgggcggc ggccacgtcc tttatctccg
     1981 cctggatcgg cagcgtcggc ccgacggcgt ccagtacctc cccgaacgtg gggatgcgct
     2041 cgccgagtcc ggcgtcgagc ttcttgagct tccgcagctt ctggtcggcg atgggaccgg
     2101 agccgtccgt cgtgcggtcc agggtctcgt cgtgcatgac gaccagctcg ccgtccttgc
     2161 tcaggtgcag gtccagttcg atgccgtcca gcccctcgcg ttcggcccgc aggaaggagc
     2221 gaagggtgtt ctccggctcg gcggccatga caccgcggtg gccgatggtg aagaaagaca
     2281 ctcgattgcc gtccttgggt gtggtggtcc ggggcagccg cacgagcgcc atacccccgc
     2341 cgggcggcgg gcgaccgccg gtcggagccc ccaagcctaa cgggcccgtc cgggcgcgcg
     2401 ccccggcccg cctggaccgc gccggagcgc gccccaaggc acaaacgtac cgaccagggt
     2461 gcccagccgt cctgggacgc aggcccggcc tacgccccct gggcgggcgg ctgcttcggc
     2521 ggcgccggcg gcgtggtcgg cggcctgctc cccggcaccc tgctcgccag cctgctcagc
     2581 gcgccatcgg ccttcgccgg cggaggtaac ggcttggggg gtgacatcgg tctgccggcg
     2641 ggcggcgaat tctccggcgc ggacttcagc gcctcggacc tcgcgggcgg ctcctgggac
     2701 ttcggctccg acggcggtgg cgatttcggc gacggcgact ggtgacctga cgcctggcaa
     2761 caccgcaagg agaactggcc tcccggaggc catcgagcca ccccgaaccc cgggccgccg
     2821 cggccggccc acccttccgg aggctccggt cggctgccct ggaccggacc gtcccaagcc
     2881 tgcaagccgc gccgaacccg tacccttcag cggcagttca gtcgagccga cgcgcaagcg
     2941 gacgtgcctg aggtgccgcg ctgacgggct gccctgccaa tgccgcccgc ctcgtgccac
     3001 cccggcgccg cacatgtact cgggtctccc acaacatggt ggcgatggtc accagggaca
     3061 gcagcaggta gaagacgaaa agcttgtgca ggtcgtcgag gacgtaccag accgacgcgg
     3121 tggcacagaa ccagaaagcg accagtgagc cggcgccgcc ctccttgctg cgtgccgcgc
     3181 cgaccaggca acaggcggcc gtcagcgcca gcagtgcggc tatcccgagg tacgagtgcg
     3241 cccacccgtc attggcgcgc cgcagttccg agttgaccgc cacggcctcc gccacaggcc
     3301 cccagcccac tgcgcacgac aggcgtcccg accacggcag tgtcaccagc cccaacaggc
     3361 ctgccgcggt ggcaacccag ccgaagtggg ctgtgtccac aacgtgacca cgtgcgcaca
     3421 gcagcgacag cagacacccc agcagggcca aggcgctgtc gaccgtgggg cgcagcgcga
     3481 acctgtggtg aagcgcggtt cgagtgccgg atcgtgtcgt cggagggaac ggggcgggag
     3541 cctgggccgt cggcatggcg gactgggcca ggacgccggc gagggcgtca cccatctgcc
     3601 gcgcgtcagc gaatcgttcc ttcggatcct ttctcagagc acactgaatc accgcctcca
     3661 ccgccgacgg cacgtgcgag cgaagccggg agaccggctc gggttcggcg aacaggtgct
     3721 gatgcatgac ggcgaacggc gattcaccgc ggaacggcgg ctgcccggtc agaagttcgt
     3781 gcagcagaca ccccatggcg tacagatcgg cccggtggtc gatctccgcc ccgctgatct
     3841 gctcgggcga gaggtaagcg ggggtgccta tggcggcgcc gctgccggtg atgcgggtgg
     3901 ccgtctcggt gaaggctttg gcgatgccga agtcgaggac cttcacggtg ccggggccgg
     3961 tgcgcatgat gttcgagggc ttgatgtccc tgtgcacgat tccgtgttcg tgactgtgct
     4021 gcagcgcgtc cagcacggca catgccgttt cgatcgcctc ggcgacgggc agtgggccat
     4081 cgcgcaggac ctcggcgagt gtcgagcccg atacgtattc catcaccaga tatggccgtg
     4141 ggccgtcggg gtcgggttcc tctccgacat catgaatgat ggccacggcg gggtggttga
     4201 gcgcggccgc cgcatgtgcc tcacgtcgga agcgggctcg tgactgcgga tcgtgggcca
     4261 gcgccgagga gagcagcttg accgcgacag tgcgacgcag ctgccggtcc accccccgat
     4321 gaaccgttcc catgccgccc tgcccgagcc tctccaccag ctcgtaccgg ccactgagga
     4381 ctgtgtcgcg ccccactaac gcctccccgt tcatcagcaa cccgacgaag cttacgactc
     4441 ctgcgatccg aggccatcga ggtggtggcc gaggcgtccg gcggcgccca agccatcgaa
     4501 cgcctcgccc cgctgttcca ccctcccgat cagcagggac agctgctgcg ggcgcaggcc
     4561 ggagatccac cgaccttttg aataaccttc cattggggac ttcttaccag ggggccttaa
     4621 ggtgccccgc catgactcga acacggctct accgcagcgg aaacctggtc ctggaagact
     4681 tcccgaccgc cgacatatcc gaatacgtga atgatcccga cgtggcggtc tggctcgacc
     4741 tgtgcgaccc gtgttccgcc gacttcgcca tgatcagcga agagttcggt ctgcacgaac
     4801 tcgcggtgga ggacgcacgt caggaacacc agcgacccaa gctggaccgt taccgcaccc
     4861 acgcgttcct cagcgcctac gtcgtaagca cggacgagag cagcgggcgg ctgacggcaa
     4921 gcgagttgtc agtgttcatc acacccacgg cattgatcac tatccgaccg aacgagggct
     4981 tcgacatcga gaaggtcgtc gagcgctggg acaacaacag cgatctcgcc aagtacgggg
     5041 tgggcttcct cctgcacggg ctgctggacc acatagtcga cggtcatttc gccgctgtcc
     5101 aggacctgga cgaccgcatc gaagcggtcg aagacctgct cttcgacgag ggacgccagc
     5161 agatggactc cgtccagcgt gactcctacg cactgcgcaa gaacctgacc aggctgcgtc
     5221 gcgtggtact gccgatgcgg gaggtcgtga acagtcttct ccggcgcgac ctgcacatcg
     5281 tcgccgagcc gctgctcccc tactaccagg acgtctacga ccatgtcctc agggccatcg
     5341 agtggaccga gtcactgcgg gacatgatca cctcaatcat ggaaaccaat ctgaccgttc
     5401 agggcaaccg catgaacctg atcatgaaga aggtcaccag ttgggcgtcg atcatcgccg
     5461 tgcccaccgc cgtcacaggc ttctacggac agaacgttcc atatccgggc ttcaatactc
     5521 atgtcggctt tctcacgtcc accggtgtca tggctgtcgg aactgtcgtg ctctacctcg
     5581 tcttcaagcg caaggactgg atctgagcac agacctgcct gcacctgttg cccgccgaag
     5641 ccacggcatc acgtgaactg ttcgccatcc acctcgagcg gagcacccgg acgaccgagg
     5701 aggcgctgct tcgaggacgt gggccggggc gtcggcgatc cactcgccca ccgccggcag
     5761 cgaggtcgtg ccggccagaa ccgcgcacgc ggtcagcccc agcaccacga ccaggcggtg
     5821 gcgcacccca cgccgtcatt gggaaacaga acgggggaga tgctcacgcg caccatccgg
     5881 attcgacgca cagttatgca acagtgagcc gcacccgatt accccaacct catacgcaac
     5941 attggaattt cctcttgtgg cacctccccg gctagctgta gcctgcggta cgcaaagata
     6001 agggcacgcc aaatggcacg ctaaatgcca tacccatcgc gtggaacggt ctaccgaaaa
     6061 gtctctgcat cgcgcgcttt ctgagaaaac ggggggacga tgggatgcat tccctattga
     6121 cgcgattagg ggaatggtgt cgactcgagc acctgattca gaatgtcatc gcaggcctga
     6181 cgacgttgtc gtgcgccact cccctcgccg cgcccccagg gcgaaatcat gagtccgaga
     6241 taatcggttt gcctgccctg ctcggcaggc atgtgacacc gccggagtcc cacggggctg
     6301 cgcatcccct gggaagttgc atacagacac gggctctgat gcacattcag gtcaccgcaa
     6361 ctcgtcccgt caagggaagt cccgcaactg tccgcgcatc ctcccggcca cccacgcgcg
     6421 tggctgcgcg ccaggcgtta ccagcagcga caacaaagcg gtaccaactc gcagccctgc
     6481 caccgaagtc cctgtgaacc ctccgcaccc tcttgcgccg tccatccggc ttactcgcgc
     6541 cggaagcccc cgcaccccgt ggaggcaact catggacgca ctcggttcca agcctttgga
     6601 tccacgcgac cagggcgccg accgtatccg atagttccgc tcgaaagaca acggggagtt
     6661 cagcgatgtc cgagtccacc acgcctgccc gcacgaaccg gccagccgac acttcccgag
     6721 cgcgggcgaa cgtccagatc tcctttactc cgggagcggt agatctgccg tcgcttgtgc
     6781 cgatcatgta tacctacatg ttccggaata tcgccagtga cggcttcgta ttcagcgatc
     6841 cgcagtcgcc gggcgacatt tcccgggact cgaagccggg gtgcatcatc gccgccccct
     6901 ccttcccggc cgacaccccc ggcatcgacg aggactacgt cttcaactgg gtgcgcgacg
     6961 gggccatcac ggccatggag gtggccaagg ccgacatgct cacccgcccg ggcgggacgg
     7021 tgcagacgct caacgattac gtgcagttcg ccgacctctg ccactccagc atccagccgc
     7081 cgttgaccaa gggtcacgcc tgcttcaaca tcgccggcga cgcccgcccg tggaccgagc
     7141 agaacgacgg tccggccttg cagacggtca ccatcctggc cgcctacgac cagctcgatc
     7201 tcggcaccca gaagcgggcc gtcgacctgg tgaacgcgaa cgtggcctac ctcctcggcg
     7261 tctaccaggg ccccaccacg aacctgtggg aggagcacag cgggtacagc ttcttcgccc
     7321 gctccgccca gctgcgctgc ttcgaggagg tccaggcctc gaccatcgtc ggcatcgaca
     7381 agccgaccgg actgcggccc gccatcaagt ggttgcgcca ggcccttgcg ggccactggg
     7441 acgggatcaa gtacgtgagc atgctggccg accccggtga cggggcccag ccatcgcccc
     7501 agaatccggt cgtcagcggt tacgacccga acatcgacat cgtccagtcg gccgtctacg
     7561 gcgccctccc cgtcaccgac accaagctgc tggccacagc ggcccaactg cgctcgcagt
     7621 gggaggaggg cggcatcgcc ttctactcga tcaacaaggc cgacaaggag gcgttcggta
     7681 tcgggccgtt gttcggccgc tacccgggcg acgtctacga cggtgacacc gcgcacccgg
     7741 tgctcggcgg ccacccctgg gccctctcca cgtgcaacgt cgccgagctg cactacaagc
     7801 tggcctccga gatcaagtcg agtggcaagg tacccgtgga cgacctgtcc gcacccttct
     7861 tcgcccagtc cggcatcgac gcgtccacgg ccccggcggc agccgccgcc gctttgacgg
     7921 cgaccggtga cgccatggtg cgggccgtcg tctaccacag tgacaacttg gagctctccg
     7981 agcagttcga cggcaccacc ggcttcgagc gcagtgtgca caacctgacg tggagctatg
     8041 ccgcctacct gtccgccatg cgggcccggg ccgaggccgt gtgacccatg gacgaccgac
     8101 tccaatcccc accaccacac cggtcccggc cgcgcctggc agcggaggag tgactgcccc
     8161 atgtacgcga agttccccga gggggcggcg aagcgcaccg accccgcggc ggcggccgag
     8221 gttctctacg acgccgtcat cgtcggcggc gggatcgccg gcgccctcat cgcctcgcgg
     8281 ctgagcgacg ccggcaagag ggtactgatt ctcgaagcgg gcccggccga ggacctcacc
     8341 ctgaggggct acgagagcta cctcgaccgc ttctactcgg ccaccagcaa ggacaaccag
     8401 tccccctacc cggtcttcgc caacgccccg atgccccgcg gcaccgacgc acggcgcatc
     8461 ttcccgggcg cgcccgacgc ctcggcctac atcgtccaga gcgggccctt cgccaccgac
     8521 accacctata cgcgggtcct cggcggcacc accatgcact gggaggccaa gacgctgcgg
     8581 atgcttcccg aggacttccg catgcgcacg ctctacggcg agggggccga ctggccgctc
     8641 acctacgagg acctcgcccc gtactacaac gaggccgaac gcgagatcgg cgtctccgcc
     8701 gacgtcgagg accaggccta cctcgggatc accttcgacg agggctacgt gttccccatg
     8761 aaggggctgc ccctgtcgta cctggaccgg atggtcgcca aggacctcga cgggatgccg
     8821 gtcgagctcg acggggagca gcgagagctg cgggtccggc cgttcccaca ggggcggaac
     8881 gggataccga acccggccta cgacggcggg aagggctacc tgccgcgagg ggcggtgagc
     8941 acgtaccagg tcgaggtcgg cgggcggtgc cagggcaaca acaactgcgt gcccatctgc
     9001 ccggtgcagg ccaagtacaa cgccggaaag accctcgctg tggccctcca gagcggccgg
     9061 gtcgacctgg tggcccaggc ggtggcccac aaggtgcacg tcgacgagca gacccgccgg
     9121 gtgacagaga tcgagtaccg ccggtacgac cggcccgaca gccccggctt caccagcatg
     9181 cgagcccggg gccggctgtt catcctggcc gccaacgcgg tggagaaccc ccggctgatg
     9241 ctggcctccg gcctgcgcag ttcgagcggc ctgatggggc ggaacttcat ggaccacgcc
     9301 tatctgctgg cgtgggccct gctgccagag gtggccggca ccttccgggg cacgaactgc
     9361 acgggcggca tcaccgacct gcgcgggggc cgcttccgcc gccgccaggc ggcattcagc
     9421 gtcgacatcc acaacgacgg atggggctgg gcccgggggg cgccgatgac cgacctgatc
     9481 gacctggtgg acgccggtgg ccgccacggc gaatccctcc gccagggcct ggtggaccgg
     9541 gtgtcccgcc agctgcagtt ggcgttcatg gtcgaggtcc ccgccaaccc gagcaaccgg
     9601 atcaccgtgg acccggccta caccgaccac ctggggaaca tgcggcccat cctcacctac
     9661 gacatccccg actacacgat gcggggggtg gcgtacgccc ggcagctgtc gcgacggatc
     9721 ttcgcccgcc tcggagccga ggaccacacc gagtacgacc cgaacttctg gggctacgcc
     9781 gtccacgccg gcgaggggta cgagatccga gggggcaacc atctcgccgg cacccacacg
     9841 atgggccgcg acccgtcgac ctcggtggtc gacccggatc agcggtgctg ggatcacgag
     9901 aacctctacc tggtcggcgg gggaagcatg cccaccgtgg gcacgtcgaa cgtgacgctc
     9961 accatcgccg ccctgtgcct gcgcagcgtc cgggccatgc tggcccagct cgacgccgag
    10021 accgcaccga tcgaggtcac ctcgaacgcc gccacccggc gccagcctca gggggtgacc
    10081 cggtgaccgc gtcgaccatc gaaaaacgtg acgacctgat cagctacctg cacgcggcga
    10141 tggcactcga gcacgcgacc atcccccctt acctgaccgc gtactactcc atacactcca
    10201 ccaccaactc cgacgccgcc cacatcatcc gggtggccgc ggtggaggag atgctgcacc
    10261 tgaccctggt cgccaacgtc ctgaacgcca tcggcgggaa gcccgacctg acccgccccg
    10321 gcttcgtgcc gtcctacccg gcctacctgc ccgacgggga ggacgacttc accgtcgacc
    10381 tgcggccctt ctcccccgag gcggtggaga cgttctgcaa gatcgagcgg ccgggcaagg
    10441 cccccagtgc cggcgcacgg ctggtgcgca gggccgacag cgggaggccg ctcctggcct
    10501 ccagcccgac ggccgaaggg atgcgcttct acagcatcgg cgagttctac gcggagatca
    10561 tcgaaggcct ggagaaggtg gcggccgacg accccgggct cttctgcggg aatccggccc
    10621 tgcaggtggg gcccgagtac tactactccg ggggcggggc ggtgatcgtc gtctccgatc
    10681 tggactcggc ccggcaggcg ctgcgattca tcgccgctca gggcgagggc ctcgactcgg
    10741 gcatctacga cgcggacggg gagctggccc actactaccg gttccggcag ctgcagctcg
    10801 gccgctacta ccaggtgggc gacggccccg acgccccttc ggggccgccg ctcagcatca
    10861 gctgggacga tgtgtacaag gtgaaggtga gcgcccggct ggccgacttc ccggcgggat
    10921 cggaactcgc ccgtgtcgcc cgggacttca acgccgaata cggggccttc ctcgccctgc
    10981 tcaccagagc gttcaatggg cagccaggcc tcttgcagga cgccgtctgc gacatgttcc
    11041 gcctgcgcga cgggttcaac cggctggtac gcaaccctct gcccggcggc ggcggcctgc
    11101 acgccgcccc taccttcgag atcccgaccg cggtcggggc cgatccggag gcctctcagt
    11161 ccgccggtga gacagcgcgg gcggtgacac ggtgaccgca ccgccgtccg aagagtacga
    11221 ggagttcgag gagttcgagg agttcctccg cctctcggtc gacctcaccg ccttcgagga
    11281 gaccgaactg ctcggcaccg gtctggcccg ccggtacctg gccaaagtgc gggccgcctg
    11341 cggcgacgag atcgtcaccg ccctcctgga cgcccaccgg gcggcccggg ccgacgcagc
    11401 cggtgatgcc ggaaggcttg accggatccc actcgaccga gccctgctcg accgggccct
    11461 gcgccaccgg atcttcagcg acgaccgcct cggcccggtg gcccgcaatg tgatcaaact
    11521 ctggtacgcc gggatgtggt acgcgctgcc acccgagtgg accgaccgct acggcgccca
    11581 cgccgcgggc gagacctcca cggtcaccgc cgcctcgtac caggaggggc tgctgtggcg
    11641 ggccatcggg gccaatcctc caggtgccaa ggggcccggc tacggctcct gggcccagcc
    11701 accccgcatc gaggaccgct acctgaaagg ggcgacgaaa tgacaggatt ggcggaccgc
    11761 ctcggcccgg acaaggtgaa gctcggcgtc tgctgcaccc tgtggtggaa cgacgacttc
    11821 cccaccatcg acgccggcat ctccttcggc caggccgcga gcgagatggc gctcgccggc
    11881 ttccagggct gcagcatcgg gcacaagtac ccctcggacg ccgccgtgct caaggccgcc
    11941 ctcgatctcc gcggccttcg ggtgtccgag ccctggacga gcacatactt cacgatcagc
    12001 aagatgcggc agaagacgat cgccgccttc gaggagacgc tggcccatgt cagggcactg
    12061 ggcgggaccg agctggtcgt ggccgagttc ggagcttcgt cgcacctgct ccccgtcgac
    12121 gtgttcgcca accgcccgat cttcaccgac gcccagtggg acgccctgac gtcgggcctg
    12181 cacgaactcg ggaagatcgc caactcggcc gggatgaagc tcagttatca ccaccacatg
    12241 ggtaccggcg tcatgacccg ggccgacgtc gaccggctga tggcctcgac cgatccagcc
    12301 ctggttcacc tgctgctcga caccgcccac atcgccttcg ccggcgacga tccgctggac
    12361 atggcccggg cctacgccga ccgcatcggc cacgtccatc tgaagagcat ccggcccgag
    12421 gtcgtgagcc gggtgcggga agaaggcctg tcgttccagg agggcgtcga gctcggcgtc
    12481 ttcaccgtgc ccggagacgg cgcgatcgac ttccggccca tcctcgaagt gctggccgat
    12541 gccgactacc aggggtggct ggtcgtggaa gccgagcagg acccgaacaa ggcgatcccg
    12601 ctcgagtacg ccaagaaggc ccgcgcctac ctcgccgacg tcttgggctg gtagcgaacg
    12661 gaggacaccg ggaatgaacg cgacattcaa acgggacgtg ttcttcagct tcttcatgtt
    12721 cacggccgat ttaaggccgc aggactcacg ttacaccgca gtcctgatca atcatctgaa
    12781 ggccctcacc gacatgggct acgacggctt cgacctgcac atcgcctccc agcccgcgac
    12841 cgtcgaccat aagctcgaga ccgacagcta tgtcgccctc aagaaggcgt tcgaccaagc
    12901 agggctgaag gacgtgaagt tcacgaccaa tgtcgggacc acgcggacct tcgacccgac
    12961 ttcaccttac gaggagcagc gcaggcaggc cctgtcctac ctcaagtcac gcgtcgacat
    13021 cacgcgggtc ctgggcggcg actcgatcat gtcagggccg ttcctctacc cctacggcgt
    13081 ctttccggtc acggacgctg atgagccgat atggagcgat gccctccaag actggatgga
    13141 gtcgcgctat cgcgcagcgc gttccgtctt cgaggatctg gcggagtacg ccgcggcgcg
    13201 agaagtgaag ctcgccatcg agcccgtcaa aagctgggag acgcccccac ccaacatggt
    13261 ctcggaggca ctggatttcc tcgatggcct cgatcactcg caggccggcg tgacgatcga
    13321 caccgcgcag gtcgtgatgg agagccaggg cccgtcggtc ttcaaggaca atgtcgcgaa
    13381 agccgcccgg caggatcggc tccactacgt ccacatatct gcgcccgacc ggggtgcggt
    13441 gaaagacagc tggatcccct gggacatcat cctgaacgag atcgagccgg tgtatcgcgg
    13501 gccgtacctg gtcgaggtgt tcaacgccat cccgccgttc gtcaactcta tgcgcatggc
    13561 acgtcggcgc ttctggcggc ccggcgagga cgacccggta ccccacgtcg acagcgccta
    13621 cgacgtcgcg agggccgcac tggaggaact gcgggagcag atcatcattc cttccgcccg
    13681 agtacctcgg aaaggtcccg catgctagcc caggtgtcag atcccatcat catggtcgtg
    13741 aagcagacgg gcgatgtccg tattcacacc ttcgtctcgt ccttcgcgta cagcaatatc
    13801 gcgaacgcca cgcatatcat cgagaccagg aaccagctgg ttctcgtcga cgggcagttt
    13861 ctcgttcctt atgcaagggc gttcagggac tacgcagaca gccttggcaa gccgatcgag
    13921 aggctgtacc tctcgcaccg gcaccctgac cactggttcg gtctggggac agcgttcagc
    13981 gacatcccga tctacgcgct gcccgagacc atgagcttca tccaggagca cggtgaagcc
    14041 tcgcgaagtg accactggaa actcggcgac ctcgctccgg accggatagt cgtgcccaag
    14101 caggccgtca gccccggcac cgagacgatc gacggggtca ggtacctctt cgaccgggtg
    14161 acagaaaccg aaatcgactt ccacctgacc atcaggcttc ctgatctggg agtttatttc
    14221 actcaggacc tgctctacag cggcacccat ctgtacctga cgcagcatat ggaccactgg
    14281 atccaggtgc tccaggaaat gctgctctcg gactacgacc tgttcatgcc gggccacggc
    14341 ctgccggccg acaaaaatga ggtcgctcgc aacatcgagt acctctcggc cgcccggcag
    14401 gcgatcggca acgggctggc aggcgacgcc ttcaagggtt tcatgctcca gcggtatccg
    14461 gaacgcaaat gcccgggcat attcgacata tatatgcccc ggctgttcgg cggtgcgagc
    14521 gactactgac caaggaggtg ttcaaccatg aacgacggct gcactgtagg acagtacctg
    14581 atagaccggc tccgtcaact gggattggag catctctttt ccatcgcggg cgactattcg
    14641 atagaatggt tgaaccggta cgtcacgcca agcagcattg aaatcatcga ggaagtcaac
    14701 gaggtcaatg ctggttatgc ggcggacgga tacgcaagac tgaagggtat cggggccctc
    14761 tgtgtcacct actccgcggg cgcattgtgt gccgtgaacg ctgtcgccgg cgcttatgtc
    14821 gagaaggtgc cgctcgtgct gatcaacggc acaccgagca taaagaagac catcaccttc
    14881 gagcagaccg gcttcagtgc gcatcacttc atcagcggac gtgaaacgga ccttcagtcg
    14941 ttcgagcata taacggtcgc agccgtacgg gtcgacaacc cggaccttgc gccggcgttg
    15001 atagattatg cactgaccca gtgcataagc gaacgacgcc cgatctacat cgagcttctc
    15061 caggacatgg tcgacttgca gtgcgagccg ccgaggggcg tactgaagcc ggccaggatc
    15121 ttgtcggatg agaccagcct ggaacagtcg gtggagcgga tctgcgcaag gcttgaaagc
    15181 gctgagaacc cgctcatctg ggtcggtgtg gagatcgacc gattcggcct tcaggaaaag
    15241 gccatgagcc tgatccagca gctgaacatc ccattcgtca cggaacttct cagcaaggcc
    15301 gtcctctccg aggacgatgc gctgtttgtc ggcgtgctcg acggccaggc gtcatcggcg
    15361 gccgtcacgg atctggccac gacgtctgat tttgtactgg ccctcggcgt gtggctgacg
    15421 gacatcaact cgttgggctg ggagccggac tacgacaaga ccgcctttgc gtcgttcgac
    15481 gcagtcaagt tcggaaccta tttcggcgga caggtcgcgt tggagcacct gatagagggc
    15541 atactggcac agaaaatcgc acccaaagta cggaagcttc cggagaagcc ggctcgtaag
    15601 gcgccgaccg tgggctcgtc cgacgtgatc acgtaccagg gattctacaa cttcatacag
    15661 cagtacatcg acaggaagac catcgtcagc agcgatgcga gcatgaacta cttcgggagc
    15721 ctgctgctcg atgtgccgag gccgggtggg ttcatcgttc agtcgtccta ctcgtcgata
    15781 ggttacagcg cgccggctgc gacaggtatc tgcttggcga aaagccccga ccaaagggta
    15841 atggtcttca cgggcgacgg cggcttccaa atgaccgccc aatgcctctc gacgcagact
    15901 cgcttcaagc tcaacccgat catcttcgtc atcgacaatg gcgtctacgc cgtagaacag
    15961 tggctcgctg atgcgtcggt tttccatgcc gacaagccgt tctacaagcc gtgtgtcctg
    16021 caccggtgga attacagcat gctgtcagag gtattcggtt gccgagggtg ggaagtcggc
    16081 acgtatggag agctgacgga tgccgtgacg ggtgctctga agaactcgaa cagcccatcc
    16141 atcatccagg tccgagtgcc cgacaaatca attcccgaga atgcgaaatg gaaaacccag
    16201 tagcggacaa ggagcaagaa taatgccgac gaagatcact gcaatcttcg agaacccgaa
    16261 atcccccgag gcgttcgagg ccggtcacca cgagcagatc gcgctggcga agaagatccc
    16321 cggagtccag aggatcgaga gcgcgaaggt ctggccgaag gaggatggca gcgcgacgcc
    16381 ggcttatcgc gtactcgaca tgtacttcac cgactacgac gcggccagca gggccgtaac
    16441 gaccgaagag gcatcggcgt ttgtcgccaa ggttttcgag ctggcgactg gcggtgtgcg
    16501 gctcctcttc acagatgtcg aggaggtctg atctcgccaa ctgccggtgt cttcacgtgg
    16561 ccagacgcgg acggcatcat gatctgtcgt gctgctgcgc ctggcccacc tcgctgcgac
    16621 caacgcccgg tcgctcctgc gcctgctgcc gacgagcgac cgggacaagg acatcgagat
    16681 ccttgcctgc ggcaccaact gctcgtactg caacgccagg ccgaaccgct gctcgcctgc
    16741 gacctcttcg agacccgcac cctgaccggg gcgcgtctgt acgccttcgc cgtcatcgag
    16801 gcccgcaccg agccctgggc cgagccacgc cgctccggcc gcttcccgaa ccggcacccg
    16861 cactcccggg tcaggtgtcc gcctgcgcgg tgtccgcggc gtcgagtacc tgatcgccgt
    16921 acaggtcctg cagccagttg gtctggtaga cggtgtcgag gtagcgctcg ccgaggtccg
    16981 gcgcgatggc caccgccgtg acggctcgtg tgtcatgtcg tgccagccag tccgtggcgg
    17041 cactgaccac cgttccggtg gagccgccga acaggaaacc gcgtctggcc atgcgtcggc
    17101 acatacggat ggtgtccctc tcctccaccc ggatcacctc gtccacacag gactcgtcga
    17161 gcagcggcgg gcgcatgctc ataccgaggc ccgggatcat ccggcggccc ggttcgccgc
    17221 cgaacgccac cgaacccacg ctgtccacgg cgacgatccg taccggccgg tgccactggc
    17281 ggaagtagcg tgcgcagccc atcagggtcc cggtggtgcc cgccccgacg aagaggacgt
    17341 ccagttccgg gaactggcgg gcgatctccg ggcccgtcgt gcagtagtgc gcccaccagt
    17401 tgccctcatt ggtgtactgg ctcagccaga cgtatcggtc gtcggaggca cacagcgcac
    17461 ggacgtactc gatcctcgtg cccaggaagc cgccgttgga gtcctggtcg gcaacgatgt
    17521 gcacctcgtt gccgagtgcc tccatcagca gtctcgtcga caggttgcaa cgggagtccg
    17581 tcacacacag aaagcggtag cccttgctcg cggcgatcat gccgagcgcg acgcccaggt
    17641 tcccggagga cgactcgacg aggacggagt ccggccccag gatcccgtcg cgttcggcgc
    17701 tttccaccat cctcttggcg gccttcagct tgatggagcc ggcgaagttg aaggcctcgc
    17761 acttcagata gagcaggtgt ccgcagatgg actccagatc gatgaagaga tcgccctggt
    17821 tgaagtcgta cggagcggag atgacaggca cggcggacct cctggtgccg ggccgaggac
    17881 gactgcctca gccgtagcgg cgaagttcgt ggaagaagtc atcgatgaga cggaggtttc
    17941 ccgcccggga cacctcgtcg tagacgtact tgccgacggc caggtcgagg acgccgagtc
    18001 cgaacggcga gaagaccacc ggccggtccg caggcggtgc ggcgcgtcca gccatgacgt
    18061 cgctgagcgt tccgttcagg aagtcgcggt tgccggtgaa ctgttcggcc agatggggcg
    18121 atgtgtcggc cttcaggcag tgctcgacgt catcgacgaa gttggccgag cccagcaaga
    18181 cctcgggggc gagatcgcgc agggagacat gcaggaccag ggggttgtgg ctgaaccagg
    18241 cagggtcgct gacgtgtggc cggccggaaa tggtcgcgaa gaccacgagg tcgctggcgc
    18301 ggacgaggtc ttcggcgctg tcgtggacgg tgatcggtgc ggtggcgccg gcctgccgca
    18361 gatagccgcg gaaaccggtg gcgctgtcgg cggacacatc gtgcacgccg accgcctcga
    18421 aggcccagcc cgtgccgttc agaaaggtgt ggatgtaacg ggcgatcagg cccgtgccga
    18481 agaatccgac gcgggtgggg cggggacggc cgcggctgag ccggtcggcc gccagggccg
    18541 cggacgctgc ggttctggtg gcactgatga tcgagctctc caggcaggcg aaggggtagc
    18601 ccgtgtcgtg gtcgttgagg atgagcaccg cggaggctcg cggcagcccg gcactcacgt
    18661 tctgcggaaa gctggagatc cacttcagac cgtccacgtg ggcctggccg ccgatggaag
    18721 ccggcagtgc gatgatccgc gccgtgggcc ggtcggggaa gcgcaggaag tacgacggcg
    18781 ggttgaccgt gtctccggcg tcgtgcagcc ggtaggcggc ctcgaccagt tccaccagtt
    18841 gcttctcacg cccgctcagt gcttgctgta cctgttcacc ggtgatcacc gcgaacgtcg
    18901 gcacggaagc acgctcaggc atggccggcc ggccgggcgt cgacagcaca tcggtcatcg
    18961 ctcgctcgcc tccggggtcg cacggcggtc ggccggccgc aggggctcgg ccatgccgac
    19021 caggacctcc cgctctccgg tgaatgcctc tctgctgtgc gcggtgcgga tgttgtccac
    19081 gagcagcagg tcaccggccc gccagggctc gcgccgggtg tgcgcctcat aagtggaatt
    19141 gatcagctgg acgacagcct cgtcgatcgg actgccgtcg ccgtagcggg tgttgaaggg
    19201 cagtctgtcc tctccataga cgtccaccag gtactcgcgc acctccgggg ccagcgtcca
    19261 ctcgttgagg aaggcgatct ggttgaacca gcagcgccgg ccagtgagcg ggtgacggac
    19321 gacggcgctg cggcgctgct cggtgcgcaa tgtcccgtca ggctcccagg tgaagtcgat
    19381 ggcgttggcc cggcagtagc gctcgatctc ggcgcggtcg ccggtgccga acgactccgc
    19441 caggctcgct ccgatctcgt cgttgtaggt gcgggtcagc acccagccct cccgctcgaa
    19501 ccgttcggtg aggccggtgg gcagggctcg gaggacctgt tcggcatcgg cgaccgccgt
    19561 cgccccgccc tgctcgggtg cggtaaggca ggcgaacagc atcaggccgg gcacctgaag
    19621 cgggtaactc agctcgtggt gcatgcacat cggctggttg gccggccagg tcgtggacgc
    19681 gtacaggccg ggacggtggg cctgacgggg tgcgaaagac tccctctccg cgatcagacc
    19741 gtcggccata tgcgaaaaga cggcactgac ctgatcgatg tcccgcagcc cgagaccgcg
    19801 gacgaccaac gccccgtgcc cggtgacctg cgcgcgcagc gcctctcggt gctcggccac
    19861 ccagctgggg gcgtcgtcga ggggatcgac atgcagcagt gccggcctgt ccggctgcag
    19921 ctccacgtcg agcggtgatg ccagggatga gaacggcaac tcgggttcct ttcggtcgtc
    19981 cgcctggggt acgacgggtc tcagcaggag gcaagtggta cgagggtgct caggacggcc
    20041 tgtgccgcct gggacgggcg agtgcgaagg aagtagtggc ccccgtcggc gagctcgtgc
    20101 agatcaacgt gttcggccag gagcagccag tcgcggtgcc ggtcggcgta gccggcggta
    20161 tgcgggtcgt cggcggcgac gaccaccgtg accggcgcgg acagccgcac cggcggcggc
    20221 tcttcgaggg cctcacagaa gtagcggtgt gcgcagacac agtcgtgccg gtaggccgca
    20281 ccaagatgtt cggcgtgccg ctcgttcagc tccgtcagtt cccggtagcc gccgtccgct
    20341 gtcagccgcg ccgcgatctc ggcgtcgctc cggctcgcca ggtcgccgat ggccgtgtgc
    20401 cggtcggcgg atgtgccgag cagctgcgca ccgaggaaca cgcgcgtcac ccgcacgcgt
    20461 cgctgcatga gcctcctggc cgtctccatg gcatgcgcga cacccgagga atggccccac
    20521 agcatgaccc gggtcaggcc acgcgccgtg atctcgtcgg tgacctgctc ggccacctgc
    20581 tcgatcgtcg cgaacggctc ggggtgtgcg tccaggttgt gaccggggag gtccacggcg
    20641 aggacctcca tgtcgccgcc cgccagcgcg ctcgccatcg gctggtagtt gaccgcgttg
    20701 ccgcccgcat gggggaaaca caccagtgcg tgctgcggca caccgctgcc gtccgacaag
    20761 ggcagcagca gttccgggcg ctgccgggcc gtgccgtcga ggagggcggc caggtcggcg
    20821 agcaccgggt gccgcgtgat gtccttcagg gacaccgacc ggtcgagtgc gaggctgagt
    20881 ctgaccgcgg tcagggaggt gcccccggag tcgaagaagt ggtccctgcg gccgatctgc
    20941 gcctctggca cccccagcag ctcggcccag gccgcagcca ctttccgctc gttcgggctg
    21001 agcaggccgg cgtggtcccc cgcctgcctt tctggtgccg actcttcggc cagtccggtc
    21061 agggcctttc ggtcgatctt gctgttggcg gtcagcggaa ggctgtcctg ccagtgaaag
    21121 gccgacggga ccatgtaggc gggcagtacc gcgccgagtg cctcgcgcag tacttccggc
    21181 tgccgctgtc ttccggagta gaaggcgatc agctgcttgc tgccgccgga ccgctcgctg
    21241 acgaccaccg cggcgtcccg tactccgtcc acccgcagta gggagttctc gatctcaccg
    21301 atctcgatcc ggaagccgcg gatcttgacc tggctgtcgc ggcggccgag gaactccagc
    21361 ttggcgccgg ggtgccagcg cccccagtcc ccgcccaggt agagccgttc accgggccgg
    21421 tacgggtccg tccggtacgc ctcccgggtc cgctcgggat cgttgacata cccccggccc
    21481 acgcagacac cggagaacgc gatcagcccc ggggcgccca gcggtaccaa tgacaggcgc
    21541 tcgtccacga cgtagacgcg cacgttgttg acgggccggc cgagcagcac ccggtcgggc
    21601 accccctgaa ggacctcgtg attggtgtcg tccgatgtct ccgtcagccc ataggcgttg
    21661 agcagctcga tgccgggctg gacggcgaac cagcgctgga ccagctcccg tttcagcgct
    21721 tcgccggtca ccgacacaca ccgcaggtcc ggcagtgcac gcgggttctg ttccagacag
    21781 gagaccacga cctccaggta ggagggcacg agctgcgtca cgccgaccct gcggcgctcc
    21841 agtgtgtcga cgaaccgctc cacgtccgtg atcacgtcct gttcgaccag cagggtccgg
    21901 ccgccgacca gcagcggtgc catgaactgc cacagggaga tgtcgaagca ctgcggagcg
    21961 gtctgcgcca ccacacaccc ctcgccgatc accaggtcgt cgatcttggc gtaaaggtgg
    22021 ttgagcatgc ccgcgtgctc gcacatcgcc cccttcggct cgccggtgga gccggacgtg
    22081 aagtagatgt aggcgagttg gccagggtcg acctgaacgc cgaggtcgtc ggcggcgtgc
    22141 ggctcggcgt acgccgtgtc gaccggcagc ttctcgactc ccggcagcgt gcccagcgcc
    22201 tggtcgaggg tgtgggtgct gccggattcg gtcaggacca gccggcatcc cgctcgcgac
    22261 agcgtcgccg cgatacggcc ggccgggaag tggggttcga tcggcaggta cgcgccgccc
    22321 gccttgaaca ccgccaacgt cgccgccagc cagtcgaggt tgcgctcggt gacgacggcg
    22381 accacgtcct cccggcgcag acccctggtg accagcgctc gcgccagcct gttcgcgcgc
    22441 cggttgagct cgccgtacgt gcactcctgc tcgccgtgca cggccgccac ggcctgcggg
    22501 tgtgcccgca cccgctgctc gaacagttcg tgtgcccgcg cgtcgggcag cggccgacgc
    22561 ggcccggcca ggccttccag ctgttcttgt acctcatcgg ccgacagcag gctctgccgc
    22621 gtgtggtcgg cgtccggatc cgccgtcatc agccgcagcg ccgtcaggtg gtagccgccg
    22681 atgcgagccg cggccgcggt gtccagcacg tcggtgcggt accggagacg cagcgtcagc
    22741 cgtccgcccc ggtcggacca gcgcacctgc aggacgccgt cgtccgcatg ggcctcgtcg
    22801 gcgccgatgg gaccgaacac ggcctcgtac ggcggctccg tcagtcccag ctcccgccgc
    22861 agcttctcca ccgggaactc ccggtgcgcc agtacctccg cctcggcctg ctcggcggcc
    22921 gacagcaggg cctgccagga cccaggggga atggccgacc ggcacggcag cggctcaccg
    22981 cgcacaccgg tggtgtaacc cgtgaccacc tccggttcgc cggagagcac gccaagcacc
    23041 ttgacgtgca cggccaacag cagcgcgctg accggcactc cccggtgccg gaccagttcc
    23101 cgcaccgcct ccgtcacgtc ttccggcacc ggcatctcgt gctcgtccgc tcccggaacc
    23161 ggctcccgaa cccaccgcgg cacggtggtg acaccgccgg cggtcagcac ccggctccag
    23221 aactcccggt ctgtgtccac gcccgttccc atcgaatgac cttcctcaac tcgcggtcgc
    23281 cgcagcggcg tcggctgatg acgttgctcg gccgacgtcg atggaccgga tgccgctctc
    23341 gggcatgtgc accgccggat tgccgcccca atgtgctttc cgggggactt cctcgccctt
    23401 catgaggaag gaatcgggtg ccagcaccga gccgtcgccc atggtcacgc catagtgcac
    23461 atgggcgccg acgcccagcg tgcagccggt gccgagcacg gtgccgtcgg acttgaaggt
    23521 gccgtcctcc tgcgagtggc actggatctt gctgccggcg ttgagggtgc actcgtcgcc
    23581 gatggtggcg agcgtccgct cggtcagata gcagccgtcg tcgaacaccc tcctgccgat
    23641 gcgcacgccc agcagccgcc agaccagggt cttgaagggg gttccgttga agatctcgag
    23701 gaagtggtcc ggaaccttcc acagccgctc gtgccaccag aaatacgggt cgtagatgga
    23761 gcacaaccgg gggcgcaacg gacggaacga tgcgatgcag cgctccacca ggatgaagta
    23821 cgcggtggag aatgcgaggg tgatcaccag atatccggcg atcaccacgt gtccgaccac
    23881 tccgtacaga tccacggagg cgagaccgaa cagggtgagc gcgaaggtgt gcagccatcg
    23941 cacgagcagc atgagcacca tggagcgaag gttgtagcgg ttcttcgcgg cgagccgacg
    24001 gcgcagggtg tcgcccgtcc tgagatggtc gaaccgtgtg tcacggtcca ccgagcgggg
    24061 gatctcgaag cacggtgagc cgaggagccc cacgccttca cggacctcgc cgtcgagggg
    24121 aaccatcacc ttcgtggcga gcaggcagtt gtcccccgtc ctgccgcctg ccggataggc
    24181 gatgttgttg cccaggaagc tgtgcggccc gatcgacacc ctggacagcc ggaaggacgt
    24241 gctggagaag tcggcgttga tgagggagag gccgtcggcc accatcgtcc cgctgccgac
    24301 ggagaccaga agaggtgtct cgtgctgcac ttccgtgccg aagttcgacc cggtctgctc
    24361 gacacgtgac aggtcgtatc cgagtccgcg gaggtagtgc acgatgtagg agctgtcgcc
    24421 gaagagccag gcgaagaact tgatgttcgt catgcgcgcg gtggcgcggt gcagcgcgta
    24481 gtgaaatccg tagagcggat agaccttgtc gggcttgacg accaggccca ccacacgggg
    24541 cacggtgtac agggccacca gccccagaac gacgcatccg aagaacagca cgagtgagag
    24601 caccagcgcg tcggagagca gttccgaccg ggacagtgcg gccgtctgcg ggtcgagtct
    24661 cttgccgatc gccggtacct cggtgaacag catgtacgcc ccgccgacgg ccagcggaat
    24721 gtacaggaag aacaactgga ccagggtgcc gaggccgaac caggcccggc gcgcggtacg
    24781 gcatccggcc ggagggaccc tgacgtagtc gatctgcgtg ggctgcgccg gagatccgtg
    24841 ccagtgctca ccgtccggga ccgcctggcc gcggtacagg gcggacgagt ggccgagctg
    24901 ggctcggtgc cccatcgacg tgtcgatgtc caggacggtc ttctcaccga tgaagacatc
    24961 cgcgccgagg gtgatccggc cggtctggat gcgtcccgcg tgggcccggt agccgaggaa
    25021 gaacgagtcc ttgcggatca ctgtgcccgc gccgatcgtc agcaggtcgg tgcagacagg
    25081 gacggagtgg gagaggatgg cgactccctt gccgatccgc gcgccgaggg cccgcagata
    25141 gagcacgtac agcggggtcc cggtgaggaa gaccatcgga ttggcgtgga gcagcacctt
    25201 gacgagccag aagcgcagat acgccatgct ccagacgggg aactcgccag gccgccagcg
    25261 gccgatgaga agccatttcg ccacgaccgg gaatgcgcac agcgcgacga acccgatgcc
    25321 tccgaacagc aacgaccgca gatagatgtc ggccacaccc gaaccggtgg cgatccactc
    25381 gtagcccgcg gcggtgatga atccggagac aagggagtaa cccaggaaga cgagtaactg
    25441 caacgttccg cagagaacat ggctgcgcgg gttcccgcgc ggacccgaag ccgacgacgg
    25501 cacgggtgcc ggcgccgacg gggcggccac cggatcgaca ggcgcaggag tggcttcccc
    25561 gagggccgcc gccaggccct ggatcgtggg gtgctgatag atgtccctca tggacgggga
    25621 cggtagatcc gctgtcttcc gtactcgcgc gcagaactgg gccatgacca gggagttggc
    25681 gccgaggtcg gcgaagaagt ggctgtcgac cggaacgcgc tccgcgccca gcaggtcggc
    25741 cagtgcctcc gccagcttcc gctcggtctc cgcccccgtg ggcccggtgt cgctcagggc
    25801 gacggcaggt tcgtccggcc ccgacacgac ctcggaggac tgctccacca tgcgatctcc
    25861 aagaacgtgg atgttcccga tcaaggtcca gcggattcag tttgtccagg cagcggcctg
    25921 cgtgccactt gctcactcat tcatctgtat gcgaagaacg atccgttttg tcatattctc
    25981 ctgatatcac gccagggtgg ggagcacacg gctcacccga atggcggtcc cccggacggc
    26041 accgcgcttc tcgagcgcct cgcgactggg cgaagtcctg gcctgtaatc cagcaacccc
    26101 tgggtggctc gcccgttggg gccagtggcc ccggtcatga gcccggcgtt gaccgcgttg
    26161 atggccgatg cagcgctcaa cgacccgagc gagcatcggt cgagccgtgc ggggttcgcc
    26221 gggcgtcttg cccagacgat gactggacga ggccgggcag gctccgcgtg gggcctgtac
    26281 gcggaccggg gcgagggcga gggcgagtcg accgtgttcg gcttcgtgga gcactacctg
    26341 ggcggcgctg gcagcagccc tacgggcgga caacggcacc ttctacgatc agttggtcca
    26401 tttccgccgc aaggccggta tcggcgagga catcgggatc ccgcgcgtgt tcgacgttgc
    26461 tgcatggatg cgtcaaggcc gaccagtcga ggcctcgacg aactgagccg caggggccgt
    26521 cgggagggct caggtgacgg cgggcagggg acggatcgga ccggagggca gcttgagagt
    26581 gagcccggcc ggcagccgct cgccggcgat ccacagcacg gcgttgtcct gtgtgaacca
    26641 ggtctgcgca gactcctttc aggtagtcgg cgatctcgcg ttcggccccg aggacgtgaa
    26701 agtgagtgaa ggcggccttg gtcgcgccgt tgaagtggta gtcggccagg ccctggcggt
    26761 gcagggcgag gtgcgtgatg ccgacgcgga agccgagtcc ggcgtgcatc gggccggtgg
    26821 cgtgggcgaa gagggtgggt atgccgtcga ctcggcggtg tggaccgcgg cgagggggtt
    26881 catcttcggc ctcggttcgg tgtgttcatc gtcgtggtca tccgtcttgg tcatgctctg
    26941 ggcagggcgg tggcgcggtg tcgaactggc caccccgtcc tcgtcatggc cggcgcggcc
    27001 ctggccatcg ccgactcgcc gtgtttgtgg gccacggtcg gccggagcat ggtggtcgcc
    27061 ttcggggcct tctcggtcgc ggacgtcgcg ctgccgatgc gctgtgcgcc ctcgctggag
    27121 ccgggctgtc ctgccgacaa ccgacttctg gcacaccacg accagcggcc tggtcccttt
    27181 cgtcctgttc gccccgatga cggcgttcat agccgcggca cgccccgccg cctcgcacct
    27241 tcggctggtc cggcgctggg cgcaccggct cctgccatcg tccacgaccg cggccgtctc
    27301 ttccacggcc cctacttcgg tcacccggga gggcacggca tcgcccagcc catccacctg
    27361 gtcaccgtcg ccgtctgact ctggctgccg gcagccgggt tacgacacgt cgagccgcga
    27421 tacaaccgcc gacgcgcacc gcgtgccggc cccggcaccg cagcgccgcc ccacgtgccg
    27481 cacgaccgga aagctcacag gcgagaccga cctgcttgcc tctccgctct cgcagcgaac
    27541 ggcacgccga acggcccgcg ttgccgggag cggcggacca tgcacgcgcg gcgcgcccac
    27601 ggcctccgag aagaccgaaa ggcctggaat ccaccggcga tcgcgacacg cctcggcctc
    27661 gaccagcagg ccttcgccca cggcggctca ccccgatccc gctgtgcgtc cgggagccgg
    27721 caccggccgc ccggctcgtc accgaggtga attcgcccca tggttcgatc cccgagcagc
    27781 agtgccgtac tctctgctag tcctagagcc tgcgtgacgg agggtcacgc caagtggggg
    27841 gaattcagcc caaagtgagc agaactgccg ggcaccgcgc gagtcggcgt ggtgcccttc
    27901 tcgtggccgc cgtcggcgcc atagccgccc tggccggaac tctcgtcgtc tcggtcgata
    27961 cggcaggcgc cacgaacgcc cctccggcgt acacgtccgc gataccggac accgccccgc
    28021 gtctcccagc cgccgcgccg cactggacag ccctggcggc caagcggttc tggaccgcgc
    28081 agcgcatggc agaagcgaag ccgcttccgg acgccagacc gcggaccgcg ggcaaggccg
    28141 cccaccccac gctccagggc ctcgtcaagc cgccggtgac cggtggcctg aacgcccagg
    28201 acctgcgcga ggtcccgatg gacgccacgc cgaccggcac cgccggcccg acggacacac
    28261 ccaccgacac ctcgaccccg gatccctccg ccaccgctac ggacaccccg accgccgcgc
    28321 cgacggacac ctcgtccgcc tccccgagca cctcccccag cgcgtcggac tcggcgagcc
    28381 ccaccgcctc gcccagcccg tcccccacca gcacgggcgg gacaggtccc gtcagctcct
    28441 acttcggcgg gctgccgatg gtcggccgga tgtacatgca gaccagcagc ggctcctact
    28501 tctgcaccgc gagcgtcatc aacagcccgc accacaacat cgtgctcacc gccgggcact
    28561 gcatggacgg gcgggcaggc ggcggctcgc tcgcgttcgt ccccgagtgg accgcggcca
    28621 atccccagcc gtacggcatc ttccccgtcg ccaccgactc cgaaggccgc agccgggtct
    28681 ggatcgatcc ccgctactac gaccgcggac acgtccaggg cgcctcgtgg gacatggcgt
    28741 tcgcccaggt cggcgcgcgc agcgacggca agcaggtgca ggacgtggtg ggcggcaaca
    28801 acctggccac cggccgcggc tacgccttcc ccagcattcg gctggtcggc taccccggca
    28861 ccgccacgca gcccctgacc tgcgacaaca acaccacgca gtacaccccg accgacggca
    28921 cccccggctc gtacctccag atcgcgtgca acggcttcgc ctccggcacg agcggcagcc
    28981 cgttcctgga gaacttcgac ccgaccaccg gcaccggcga cgtggtcggc agcatcggcg
    29041 gctgggacac cggcggaccg accgacgacg tctcctacag ctcgtcctac ggttccgacg
    29101 tgcagaacct gtacaaggcg gcggtcgcag gcaccgcccc cgcgcgtccc aatgtgctgc
    29161 ccggcgcctc cacactcacc catgccaccc tcgtcacttc cggctccttc acgccttcgc
    29221 cttcgcccga tccggacaag ggcgacctga tcgtgtgctg gtcggacggc gagctgacgc
    29281 tgtaccgggg tggtggcaac ggacggttcg acaaggagat acgactcgtc gcggccaaca
    29341 ccacctggac gaaggccgtc tccatcacgg gcggcgactt cacgggcacc gacacctacg
    29401 acctgctggt gcgctggagc gacggcagcc tcaccctctt ccccgacgtc gacgcgcgcg
    29461 gcctgcacag ccagatcacc ctcgtcaagc cgggcacgct gtggcagcac gaggtcgcca
    29521 tgaccgcggg ccgctacacc accgacgacc actggcccga cgacctgatc gtgcgctggt
    29581 ccgacggcga gaccacgctc tacaagaaca tcaactccac cggcctccac agcgaggtcc
    29641 ggctcaaccc tgccaactcc acctggacgc acgccacatc cctcacgtcc gccgacctcg
    29701 ccgggaccaa cgagtcagac ctcgtggtcc gctggtccga cggcgaactg accctgtacc
    29761 cggacatcaa ccagtacggc ttccacggag aggtgcgact gcgggccccc agcacgctgt
    29821 ggacccacgc cacgctcacc gcgtcgggca acttcaccag caccgacacc cggcccaacg
    29881 actacctcgt gcgctggtcc gacggccaac tgtccatgta ccaggacagc ggcaacagcc
    29941 tcggcacgga agccgtactc gcgaccgcgt ccggctcgtc actgccgtac taccggcgct
    30001 gaccacgaag tcccctgggc ctcggcccag gggactcctg gcggtggttt gctgacggcg
    30061 ggttcgtctg ggagcaggcc gtgtggtgaa ggcgtcaact acggtctgtg gagcccggaa
    30121 tgacgaggag gctgccttgt ccgccctcgc ccggtccgct ggaagcgtac gccgtccgct
    30181 tcgatgacct cttttccacg ctggctcagc gcctggggtt tcgcgagtac ctgtccttcc
    30241 tgtccgagtc gacctgggac aggagccgac ttcgtccgtc ccctgcttcg agaccgtcat
    30301 ggtgaccggt gcccgcgtac acgttctcgc cgtcgcggaa cacgccagcc gacgagtgcc
    30361 gatcctgcgc gagtacgagc acctcgacgc gtccgtcgcc ttctgcagca agctcttcgg
    30421 caccgagccc tccaaactcc gcgacggctg tgccaacttc gccatcaccg agccccccgc
    30481 tcaagctcgt catgatcgca ggcacggcag gtgaggcgac ccgcatggac cacctcggcg
    30541 tcgaggccga acccaccgag gccatccgcg ccgccaccac ccgcctgggc gaggccggcc
    30601 tggccacggc cgaggagaac gacaccgtct gctgctacgc cctccaggac aaggtctggg
    30661 tccacggcac cggccaggag ccctgggagg tctacgtcgt caaggccgat gccgacacgg
    30721 tggaaccggc cgtcgcgagc ggttgctccc ccacgcccgg ccgacacgtc tggaccggcg
    30781 gcccagcgac ctggaacggg cgcccggtga tggtcaagcc cccgttcggc gggtccagcg
    30841 tgggcatgag ccttgtacgc gatccggcgg acctccccgg cgccctggcg gacgctgccg
    30901 acgacgagcg agcagccgtt ctcgtcgagg aatacgtgag cggcctgcca ctgacggtgg
    30961 ggctgctgga gctgccgggc gggtccgcca tcgtcttccc gccgctggcc accgaagcca
    31021 ccgaggccga gttctacgac gccgacacca agctcgacgt ggactccaag gggaccgtga
    31081 ccgtgcgcgc cgccgagctg gctcccgatg tactggacaa aatcaccgcg gacgtccgga
    31141 cgctgtggga cgggatcggg ctgcgcggct cggctcgcat cgacttcatc ctcaccgagg
    31201 acggccagcc gtacgtgctg gaggtcaaca gcacgccggg catgtcccgc gacagcaact
    31261 tcgcggtggg ggcggccatg gtcggactca cgcacaaggc gcccacggtg acggaactcc
    31321 tgaaactcgc ggtcaagcac gaggttctga ccccgggtgg agcacttcac gcggggatcg
    31381 cgagcctggc ggccgacctg ggagtgcttc gcagccgaga gtggggtcga tctcgtcgtg
    31441 gcggtcggcg gagacctcgc caagcagctc gctctcgcgg cgggcgcagc aggggtcccg
    31501 gagattgcct tggtgggcga caacgccacc gctgcctcct acctcggctc cgtcctccgc
    31561 cccggtgacg tcgtgctcgt gaaggcgtcc cgcggtggtc agctctggca gatcgcccaa
    31621 gcgctcaccg gacagcccgt caccggcctg tgacccgtct ccatctgggg tagcgacggc
    31681 gatcgcccgt ggaaggggca gccttcgtgc cctctgcctc tgtctgcccg caggcaacgg
    31741 cccggaccgc tcagcagtcc gggccttcgt cgttttcgtg gtcctggtct tggtctcagt
    31801 cgagcctttc cctccagtgg tcacgcctgg gtccccctcc aggagtgtgg actctccgtc
    31861 cggccctcgt ggtcagttcg aacatttgat agcaataagt taccaatagg acacaggagg
    31921 tagatatgtc catgctgctc atcaccggct cgtaccggat cctcggcgac cggcccgacg
    31981 gcgatacggt ccacttcacc ccgcgcgacc cggggttctg gtgcgaggtc cccggccagc
    32041 accgggtcaa gcgggacgag aacggcggcg cctcgctccg gctggacggg atcgacgcca
    32101 ccgagaccca ctacaagggg gtcgggcccg aattcgtcca ccagccactg cgcctgggcg
    32161 cgcacgccgc ccgagacgag ctgctgagct ggctgggctt cgacgacgtc gtacaggacc
    32221 ccgaggagaa ggtcacggct tcggccccgg agaccgtgcc cggctacatc ctcacctccg
    32281 gcgccgacgt ctacggccgc tgcgtcgcgt tgatcggtcg cggcgacccg ccggagatcg
    32341 gcaaccctcc gaagcccgcg aagagcggcg accggatcga cgtcaccgtg gacatgctgc
    32401 accggaccgc caatcaccac ctgctgtccc gcggcctggt gtaccccacc ttctacagca
    32461 acctcccccg ggagctgcgg gcgaacatga ccacgaccac gcaggaggcc agggcggccc
    32521 aggttccggg cggcgtctgg tcgtacgacg tgacgaccag cggcgcgaag atcgacagcc
    32581 tggcctcgct caccgacgag ttggtgatcg tgcccaagct gttccgccgc ctcgccgact
    32641 acatccggct cttcggcccg tctctcgcct gtctcccctc ctatctggcc ggcggcgccg
    32701 acgagttcta tgtccccggg cagcgcgaca gcatcgtcgg cctccagcgc gtggtcgagg
    32761 tcaccaacgg caacacgttg cggatgaccc gcccgatcga agacctcgtg ttcgtcgaga
    32821 agtagaccgg agaacgagcc gcaccatgag tgacgccacc gacttccggg cgctgtccga
    32881 actgctcacc ggcgagggca ggctgaacgc ccagcgcgcc gacgactacc gtgtgcgcct
    32941 caccgctgcc ttccccgccg acgtgccgcg gctgctcgac gcctaccgca ctgtcacgag
    33001 ccaggacgac ccgggcaagg ctctggttga cgcggtcaac gccgacccag cccttgcacg
    33061 gctcacccgg gagaccatca ccgtctggta caccgcccag ttcacccggc cggacggcaa
    33121 acccgacgcc ccgggcacac ccgcccagta ccaggacggc ctgatctggc gtgtcatcga
    33181 ggcccacccg ccgtccttcg ctccccagcc gccggcgccg agcggctacg gctactggac
    33241 cgaccacccg tgagtcgagg agacgccccg tcatgaaccc ccagtacgac gtcgtgatcg
    33301 tcggcggcgg agcggccgga gccctcaccg cctgccggat caagagcgcc aagccggacg
    33361 cccggatcct gctcctcgac gccggcaaca acggcaccgc caagcccgac cgtgacgcgt
    33421 tcgtcgcggc ctaccagacc gccgcgatca agaacgtccc ctccccgtac gcgggcctcg
    33481 acaacaaccg gctcggctac gccccctcct cggacggggc ccccgatccg gtggcgatga
    33541 accgctacta cgtagagacc ggcccggacc tgtacgagag cggcttccag cgcatgctcg
    33601 gcggcagcac ctgggcctgg cgcggcaaca ccccgcgctt cctgcccaac gacttccagc
    33661 tcaagaccaa ctacggcgtc ggcgcggact ggccgatcgc ctatgcggac ctcgagccgt
    33721 actacgtcca ggccgaggcc gaactcgggg tgtccggcaa cgacgacgag tgggtcggcc
    33781 tcaccccgcg cagcgccccg tacccgatgc ccggcatggc gcccagctac ggcgacgagc
    33841 tcgtccgcgc cgcgctcgcc gacatcggac cgatcgacgg cgtaccggtc accgtggtca
    33901 ccactccgca ggcccgcaac tccgaagagt accgggaccg ttcggcctgc cagggcaaca
    33961 gcagctgcat cccggtctgc ccctccggtg ccaagtacga cgcgggcttc cacatcggcc
    34021 tggcccgcga tcggctcggc gtcgagatcc gcaccgcctg cgtcgtcacc cggctcctcc
    34081 cacgccccgg aaacctggcc cccaccgtgg tcttccggga ctggaccacc gccgacaagg
    34141 ccgagcagca ggtggacgcg cagcacgtcg tcgtagccgt caacgccatc gagaccccca
    34201 agctctggct gctgtccggc ctcgacaacc gcagcgacca ggtcggccgc aacctgatgg
    34261 accacctcgc caacgagatc gtcggcctgt tcggccagcc ggtcttcccc ttccgcggcc
    34321 cgcagtccgc cctcggcatc gacaccttcc gcgacggcga cttccgccgt aacaacggcg
    34381 ccttccgcat gaccatcggc aacgacggct ggggccgcac cgagccgcca gccgtcgcgc
    34441 tcgcccactt catgtgggac gacgccaaca agcggatcaa actcaccggc cagccgctcc
    34501 agcaggccat ccgggaccgc gtcacccgcc aactgaggat cagcttctcc accgagcagc
    34561 tcccggaccc ggccaaccgc gtcaccctct ccgacgaacg cgacgccctg gacatccccc
    34621 gcccgaaaat cgcctaccgc atcgacgact actccaaacg ggccctcgcc tacggccaca
    34681 gcgtcgcccg ccggatgtgg cagcacctgg aggacaccgc cggagccacc gaggtcagcc
    34741 ccttgcagcc ggacctccgt ttcctcggcg ccggccacct catgggcacc atgcgcatgg
    34801 gcaccggccc gtcggcctcc gtggtcgacc ccaccggcca gtcccacgcc caccgcggtg
    34861 tctgggtcgt cggctcgtcc gtgttcccca cctgcggaac cgccaacccc accctcaccc
    34921 tctccgccct caccctgcgc accgccgacg ccctcgccgc caccctgtga ccggccgcgc
    34981 cgccgacggg cccaccagcc tggcggcggc gcccacttgg aggggtccct cgcacccgtg
    35041 accatcacga ccaggctggt cctggcccgc cacggcgaag cccagtgcaa cgtcgacggc
    35101 ctcgtcggcg gcccgctgac ctgcactgga ctcaccgtcc ggggccgcga gcagacccgc
    35161 cgactcgcca cccgcctcac cgcagaacac cgcaccgggc ccggcttcga cgtcctgtac
    35221 gccggcccca gagccaggct ccaggagagc ggacggatcc tcgccaccgc cctcgatcta
    35281 ccgctgctca ccgacccggg tctcgacggt ccccgccacg ggcaggccga cgggcggccg
    35341 tggcgcgacg tcgaagccga gttccagggt cgccctgccg ccagccccga cctgccgtgg
    35401 tcgcccggct ctgacacctg gaacggctac ctgctccgcg ccggccgcgc cttgacggcg
    35461 ctgctggaac ggcacgctgg ccagagcatc ctcctcgccg gccacggtga gaccatccac
    35521 gccgcctgcc acctgttgct ggaactcagc ccctccacgt catcccgcat cgacttcggc
    35581 accgagcacg cctgcctcac ccgcttccac ctccaccacg acccctacgg ccgccgcttc
    35641 tggaccctcg ccgccctcaa cgacaccgcc cacctccaac agccggtcgc cgaccgggac
    35701 agttgacgtg acggtcagct gccggcggac tgtgcggcga gcgggcgcag ccggtgcgcg
    35761 tcgtcgaaca aggcgcgttc ggagagccgt acggcgatga gcgcggccag cgctgcggcg
    35821 gcgagaagca tgtacatcac gacgatctgg tagcggatcg ctgtgaaggg gtcgactcca
    35881 gcgaggatga gaccggtcat ggccccgggc aggctgatga cgccaacggt cttggtggag
    35941 tcgagggcgg ggatcagagc ggtgcggacg atggtgcgct ggtgcggggc gaaggcgtcg
    36001 gtggcggcga ggccgaggct gaggcgggcc tcgatggcgg ggcgggcggt gcggacctcg
    36061 tcgtggaggc gggtcagggc gagggcggtg gcctgcatgg cgccggagac gaccatgccg
    36121 ccgaccggga tgacgacgcg ggcctgggtg gcgatcacgc cgagggcgag cagagtgccc
    36181 atggtcgcgg ccgtgccgat ggtgatcgcg gcggtcgcgg tggggagggc tttgggcagg
    36241 gccggggtgc ggcgggcggc gacctgcccg gcgatgagga ccatgatgcc gagccagccg
    36301 atggcgcccg tcagcccggt gtggcggaag accaggagca gcagggcgcc gacggcggcg
    36361 agttggaggg cggcgcggac ggcggcgacg gtgatgtcgc ggcccagtcg gaggcgtccg
    36421 tgccaggcca cggcgatggt gagggcgatg agggcagcgg aggcggcgac tcccgcccag
    36481 gtggggacgg cggggttcac gcgtactcct ttaggtagtc gacccggtgg gcctcgccct
    36541 ggtcgacgag gtgaccgtgg tcgaggacga ggacgtggtc ggagacgcgg cgtgcctgtg
    36601 cggtgttgtg gctgaccagg accacggtca gaccgtcggc gaccagatcg cgtacgacgc
    36661 cctcgacggc tgcggtgccg actgcgtcga gtgcggaggt gggttcgtcc aggagcagcg
    36721 cctggggggt gacggccagg gcccgggcca ggcagacgcg ttgggcttcg ccgccggaga
    36781 ggttcgtggt ggggcgatcg aggtaggcgg cgggcaggtg ggcgcggtcg aggagggtcg
    36841 ccgcctcgtg gcggtcgagg tcggggcggc cgacgcgcag gtcgtccatg acggtgtcgg
    36901 tgagcaggac gggttgctgg ccaacgaggg tgacgcggcg gcgcagggtg aggacgttcc
    36961 aggccggcag ggggcggtcc tggaaggtga cggttccggt cgtgggttct tcgaggcggt
    37021 tgaggaggcg caggagggtg gtcttgcccg cgccgctcgg tccgaccagg gcggtgcagg
    37081 ccgaggcggg gatggcgcag gtgatctcct ccagcagggt cgcgtcgcca cgccggaccg
    37141 tgacctggtc caaggcgaac gcagtcgtct gtatgggctc ttctccgact gtcaccatgc
    37201 aaccatggtt acaccaatct tgccgcttcc gtcgggaggt catgttcccg gccggtacac
    37261 gagcagcgcc gggtgtccgc cggagccgtg cggaaccggg tagtagctga ggtgcgtggt
    37321 ggggtcgacg gcgacgacgt gggcgccgtc ggcgaggtgg gcgcggccgg tgacggtcag
    37381 gtgtcggtca tgggtgtcgg cggtggtgac ccagccggac tccgctgcga cgtagaggtg
    37441 acgggcgggg gcatcgtagg cgagcacgtc ggggtcctgg ccgacctcgt cggtgccggt
    37501 gacgcgccac gtggccaggt ccagggtgag caggcgggcg ttgccgtcgc aggcgacgaa
    37561 ggcgagtcgg tcggcggagt caagggtgag tccgtggtcg tggtcgcagc cgggcagggg
    37621 cacccggcgg gtgatgtgga gggtggtcgg gtcgatgacg gcgagttcgt tgcgggtctg
    37681 gacgtcgacg agcatctgcc gggtgatggg ggcgtaggcg acgttgccgg cctcgccgcc
    37741 caggggcacc gtgccgcgga ccgctccgct gccggcgtcg acgacggtct ccgagccgcc
    37801 ggactcattg gtggtccaca ccctgttgtg cacggggtcg taggccagcc cgtccggagt
    37861 gccgccggtg ggactgcggt gcaggacctt gccggtggtc tcgtcgatgg ccgcgacctg
    37921 gtttgcgtca ctggcggtgg cgtacacccg gtgcagggcg gggaccacca gcacgccatg
    37981 gacgccgggc aggtcgtaga tggtcctcac gaccttgtcc gcgtgggtgt ccacctcgat
    38041 gacctggctc gcaccgaggt gggcgatgaa cagcaggccg cggccggggt cgaggctggc
    38101 gtagtcgaag cgggaactgt cgcccggcag ggagatctcc ttcacctggc gcagcggcag
    38161 cgcctccttg ggtggcttgt cgccgccccg ggtgagcagt acgccggcca cggctgcaat
    38221 ggccgcgagg accaggccgg cggccaggac gagcagggtg cgggggctga ggtgacggat
    38281 catgtgcggg cttcccgggg tcggcggcga aggggcccgg tcgtcctggg cggcagcccc
    38341 gcgacggccg gaccgttcag tacaggtaga tgccattcag tacaagtaga tgtcgacgag
    38401 cagggccgcg acagcggcca ggagcgcgta gcggatgctg gtgcgcgccg gctgcgcggc
    38461 cagtggatcg agaccgtagc cgagggacgc ggcggccagg gtgaagaccc cggagccggt
    38521 gtcctgccag ctgacaggga agacggtcac gggtgcgtcg gtgaagaact gatccccgtg
    38581 cgcggcacgc aggatcgcgt tccaggccag gggcccgatg gccgcggcga gcgcgccggt
    38641 cgccaggacg tcacggccgc ggccccgggc ggccgcgatg agcaaggccg cgacgacggc
    38701 cgacagcgcc gcgccgtagt cgatctggcc ccagccgatc atgaggcggg agccgggtcg
    38761 gtcgcctcca gggccgggcg cagggccttg gccaaggtga ctccgtcggc ggtggcccag
    38821 tagtgcaggt agaacaggcg gggctggtcg gtcagggagt ggttgtgcag ctcgactatg
    38881 tcgatgttgc ccttccgcag cgcctggatg accttctgca cctcgggtgc ggtcatgacg
    38941 aagtcgccgt tgatggccgc cttgttgccg ccgagcggct ggaagttgat gccggtggtc
    39001 aggccgaggg caggaggcag cacatgggtg ccgtcattga cggtctggtt gcgggcgacg
    39061 gtgaacttgt agatgccgcc gtcggtggtg cccttgcggc cgagcgcctt gtcgatgccg
    39121 gcggtgtcca gcgcgatggg cggctgggtg ggcgggggcg gcgaggccgg cggtatggcg
    39181 gtggcgtcca gcgcggactt caggccctgg gcgagtttca ccgggtcgcc catggcgtgg
    39241 acgtgggtcc accagatggc cggggactgc tggagcaggt gcttgtgcag ggcggtctgc
    39301 tcgatgcctg cggcctggag cgcgtcggtg accttgggca gttcgtcctc ggtgacgacc
    39361 aggtcgccca tgagcatggt gccgtcgtgg tacttggcga agttcgcgta gccgccgagc
    39421 gacaggcccg gcttgatcgc gacgccctcg gtggtgacct tgaggtcctt gcggggcagc
    39481 gcgatgtggt agacggtgcc cttcatcagc gttccggtgc ggccgagggc gtcagcgacc
    39541 ggcttccagt ccttctccgt ggtctgcacg ggctgctgaa ggtggccgtg tggggcatcg
    39601 gtctgtatcg ctgccgcgtt catggcgttg tcggcggtac ttctcgtctg ggtgccgcag
    39661 cctgtcagca ggccggcgcc cgtcaccagc aggagcgcgg ccgccgttcc tgcggccggc
    39721 ttggtgagcg aacggggtga catgaccact cctcgtggag atcgttgtcg tagatgcctc
    39781 tgcgatcagc gaatccgccg ctgatgaagt tggcatgaag acccacacgt acaaacgggt
    39841 gacttcatgc cgtcttcatc agcggcgggg aacgtgaaag gcgccatgac gtgcgcggtg
    39901 atgtcggacg agggaaggcg cgatgcggat cctggtggtt gaggacgagc ccaagatgcg
    39961 ggacctgctg caacgggccc tgaccgagga gggctacgcc gtcgatacag ccgccgacgg
    40021 cccgcaggcc ctcgccctca ctgatgtcgc cgcctacgac gcgatggtgc tggacgtgat
    40081 gctgcccggc ccggacggct tcgaggtgtg cgcgactctc cggcgacgcg gtatctggct
    40141 gcccgtcctc atgctcaccg ccagggacgc cgtcaccgac cgcgtacagg gcctcgacgg
    40201 cggcgccgac gactacctca ccaagccctt cagcctggac gaactgatgg cccggctacg
    40261 cgccctgatc cgacgcggac ccgtcgaacg ccccaccgtc ctgaccgccg gcgacctgtc
    40321 cctggacccg gccacccgaa ccgtgcggcg cggcgacgag gaggtgcccc tgaccgccaa
    40381 ggagtacgcc ctcttggagg cactcctgca ccggcccggc accgtactga cccgcgccgt
    40441 gctcgtcgag cactgctggg acctgggcac cagccccggc tccaacgtgg tcgacgccca
    40501 catcaaggcc ctgcgtgaca agatcgaccg accctacggc acccgcgccg tcgaaaccgt
    40561 gcgcggcgcc ggataccgga tccgccgcga cggcggccgt ccctccaccc gcacgtcatg
    40621 aaccgcatcc cgctccgtat ccgcctcacc gcgatcttcg ccgccgtgat ggcgctggtc
    40681 ctgaccggcg ccggctacct caccctcagc cgcttccgcg aatcccaggc cgagtacggc
    40741 gccgccaccg gcatcgccca ccaggcccag caggaagccc tcgacgacct gctgcgcgaa
    40801 ctgctcactg ccctgcccat cgtgttcgtg ctggccacca tcggcgccta cctgctggcc
    40861 gctgcggccc tgcgcccggt ggaacgcatg cgcacccagg ccgccgccgt caccgaggac
    40921 acccccgagt accgcctcga cgtaccaccc agccgcgacg agatcgcccg cctcgccacc
    40981 accctcaacg acatgctcac acgcctccag accgccctcg accacgaacg cctcttcgtc
    41041 gccgacgcca gccacgaact acgcaccccg ctcagcctcc tgcgcaccga gatcgaactc
    41101 gccctccgcc atccccgcga ggccaccgaa ctgcacgccg ccctcgtctc cgcacacgag
    41161 gagaccgaac ggctggtcca actcgccgag gacctgttgc tcttggcccg caccgaccgc
    41221 cgcgacacgt cggccgggtc agccgtgccc gatctggccc cgcttctgca tcgcgtggct
    41281 gcccgcctgc gcaacggctc ccccgacaag tccatcaccg tcggctgccc cgctgggctg
    41341 gccgccgcag tccccaacga ccgcctggat cgggcggtga cgaacctgat ccacaacgct
    41401 cagcagcacg gccgcggccc cgtcgaagtg accgtccgcc ccggcgagaa gtgcatccgc
    41461 atcgaggtcc gcgaccaggg ccccggcttc ccgcccgact tccttcccca cgccttcgac
    41521 cgcttcaccc aggccgaccg ctcccgcgcc accagtggca ccggcctcgg actggcgatc
    41581 acggccgcca tcgcccgcgc cgccggcggc cagtacggcg ccttcaacca ccccgagggc
    41641 ggcgccgtcg tatggatcac tctcccgccc cttccgcagc cacccgggac cgcttgaggc
    41701 acctacacca gcgtgcaacc atggttacgt tgaacgtgag ctggctgcag ggagcgtcga
    41761 tgaaccggac aacgtccacc gctgcacgga tcggtacacg ccatgaccgc tgaccggccg
    41821 ccccgcgacc cgggcgagtg ggtactgctc tcctaccgga tgccccgcga accctccacg
    41881 ccccgcatca ccctctggcg caagctcaag cgcctgggcg tcgcccagct ctccgacggc
    41941 ttggtcgcac tgcccgccga cgcccgcacc cgcgaacagc tggagtggat cgccgacgag
    42001 gcgatcgagg ccggcggcac cgcctccatc tggatcgccc ggcccgccac ccacgcccag
    42061 gaacacgaac tggccacgtc catggccgcc gcccgcgccg ccgagtacca agccgtcatc
    42121 gaccatgcca cccaggccac aggcgcggcc aacaccgcag ccgtcgtccg caggctccgc
    42181 gccgaactac gacgcatcgg ccgccgcgac ttcttcccgc ccctcgaacg cgaccgcgca
    42241 cacgccgccg tccacgccct caccgacgaa ccaggcgcct cagtgcccaa ggccgcaagt
    42301 catcgggaga agaacgcatg aagtgggcca cccgcgccgg gatccacatc gaccgggccg
    42361 cctgcgcctg gctcatccgc cggcacgtcg acaaggaggc ggagttcgtc ttcgtcaccg
    42421 accccgccga agtcccggac gacgcgacgc cgttcgacat gcgcggcgtg cagctcggcc
    42481 accacggcgg cgactgctcc ttcgagacga tcctgcgcca ctacgagctg accgaccccg
    42541 tgctgtggaa actggccgag atcgtccacg aagccgacct ggacgacgaa cgctatgacg
    42601 cccccgaagc ccccggtgtg gacgtcgtcc tgcgcggcct gtccatgatc tgcgacgacc
    42661 aacggatcct ggaactgacc ggcccgctct tcgacggcct gtacgagtac caccaccggg
    42721 gcatgctgct ggggcgcgag ccctcctgac cacgtcatcc cggagcacgc catgccgctc
    42781 gtcatcgctt cgtcacccga gatcttcagc accgcccaca tcgggctgac cgccgccatc
    42841 accggcgttc tcgcactcgc catggcgatc tggcggctgc cccgatccgc atggctcgac
    42901 atggccgcgg tcgccgtact gtccgcggcc tccgtgtacc tgtggcggac ctccgcgaac
    42961 atgacgtcgc tgaacaagga cggcctgccg ggattctccg ccaacgactg ggccgcgccc
    43021 atcctcacct acatcttcct cagcctctac gccgacgtcc gcatcccggc agacccacgc
    43081 cgctacgccc aggcccgcgc cctcgccact ctcgcctccc tggcggtcaa cgtcatcacc
    43141 atctgaccgg cgactgcgcc cattgataga gaactgcaac cacggttaca gtgcccgcat
    43201 gggatccgag gacacgacgg cgcccggcag cgcaggcgat gccgagatac cc
//
