LOCUS       NZ_CM002285            26686 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1364778
            Orig. end                         :: 1391464
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26686
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26686
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26686
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16686](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16686)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(80..93)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     misc_feature    complement(136..151)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.01"
                     /tool="antismash"
     misc_feature    complement(1258..1274)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    complement(1577..1591)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.44"
                     /tool="antismash"
     gene            1844..2641
                     /locus_tag="M878_RS56170"
                     /old_locus_tag="M878_06475"
     CDS             1844..2641
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="M878_RS56170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06475"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_023545288.1"
                     /transl_table=11
                     /translation="MTQQVPSTEPELAGVRNFRDVGGLPTMDGRRVRHGVLFRSGHLAH
                     ATEDDAAFLTSLGLHTIFDFRNAADQKLEGPDVELPGVRNVNLPLSDPADGAEFWKMVR
                     DGDLDQLRGILADGKGATRMIASYRSIVKERTTEHSQVLRALTEDSVPALMHCAAGKDR
                     AGISIAVTLLALGVERDAIVADYLESNAKHRRYKVRRSGSTEGAYTPEVMELLSPLFDA
                     RAEYLHAAFETIEQTWGGVDTYLEQGLALTPAARDHLRERLLD"
     gene            complement(2728..2850)
                     /locus_tag="M878_RS56175"
                     /old_locus_tag="M878_06480"
     CDS             complement(2728..2850)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676213.1"
                     /locus_tag="M878_RS56175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06480"
                     /product="DUF6126 family protein"
                     /protein_id="WP_023545289.1"
                     /transl_table=11
                     /translation="MSDFETKFPRSLWIRLIIYIALGHVLAGFLYLLFAVGAKG"
     gene            complement(2847..3470)
                     /locus_tag="M878_RS56180"
                     /old_locus_tag="M878_06485"
     CDS             complement(2847..3470)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676212.1"
                     /locus_tag="M878_RS56180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06485"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_023545290.1"
                     /transl_table=11
                     /translation="MNASDAGPPAGPGDELTAVAPQLRALRRRAGLTLEAAARAAGLSP
                     AHLSRLETGRRQPSLPMLLALARIYGTTVSELLGETVADRDAIVRAGDMEPTRAGGWTY
                     FQAGAPGRAMHALRVRVPYGSQGDIVRVHPGEEWLYVLRGRLRLRLGDTAHLLGPGDSA
                     HFDSLTPHRLAAEDHDGVELLFVHTLLQSPTATLCLGPLTRELP"
     gene            3592..3879
                     /locus_tag="M878_RS56185"
                     /old_locus_tag="M878_06490"
     CDS             3592..3879
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054490.1"
                     /locus_tag="M878_RS56185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06490"
                     /product="hypothetical protein"
                     /protein_id="WP_023545291.1"
                     /transl_table=11
                     /translation="MSARITPDRADTPAVALGPVSLVLGIVAAVGAWPALTLALLPLCL
                     IAGGLAVTFGLMGMYHAGRGVGSPWTAATGTVLGAAGLTAPFILVVLLSA"
     gene            complement(3883..5268)
                     /locus_tag="M878_RS56190"
                     /old_locus_tag="M878_06495"
     CDS             complement(3883..5268)
                     /NRPS_PKS="Domain: Aminotran_3 (41-363). E-value: 2.1e-86.
                     Score: 282.0. Matches aSDomain:
                     nrpspksdomains_M878_RS56190_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494124.1"
                     /locus_tag="M878_RS56190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06495"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_023545292.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.6e-85, bitscore:
                     284.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTEFDLGALLAERGTERYELHAKYLNPQLPRMLHTIGFDRVYER
                     AEGAHFYDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDLNLADLTRFDCQPLPGL
                     LAERLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRVLYCDHAFHGLTTGSLSVN
                     GEGGFRDGFAPLLPDTAVPLGDLDALARELKKGDVAALIVEPIQGKGVHEAPPGYLRAA
                     QELLHRHKALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVCVAKALSGGYVPVGATLGK
                     DWIFKKVYSSMDRVLVHSASFGSNAPAMACGLAVLSAMENEQIVAGVRSTGELLKSRLT
                     GLVDKYELLADIRGRGLMIGIEFGKPSSLKLRSRWTMLQAARKGLFAQMVVVPLLQRHR
                     ILTQVSGDHLEVIKLIPPLIIDEADVDRFVDAFTAVMDDAHSGGGLMWDFGKTLIKQAV
                     AGR"
     aSDomain        complement(4180..5145)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS56190_Aminotran_3.1"
                     /evalue="2.10E-86"
                     /label="M878_RS56190_Aminotran_3.1"
                     /locus_tag="M878_RS56190"
                     /protein_end="363"
                     /protein_start="41"
                     /score="282.0"
                     /tool="antismash"
                     /translation="VYERAEGAHFYDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DLNLADLTRFDCQPLPGLLAERLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRV
                     LYCDHAFHGLTTGSLSVNGEGGFRDGFAPLLPDTAVPLGDLDALARELKKGDVAALIVE
                     PIQGKGVHEAPPGYLRAAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAPAMACGLAVLSAMENE
                     QIVAGVRSTGELLKSRLTGLVDKYELLADIRGRGLMIGIEF"
     gene            complement(5265..7163)
                     /gene="dxs"
                     /locus_tag="M878_RS56195"
                     /old_locus_tag="M878_06500"
     CDS             complement(5265..7163)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676210.1"
                     /locus_tag="M878_RS56195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06500"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_023545293.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.9e-111,
                     bitscore: 370.1, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.9e-06, bitscore:
                     25.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILENIRGPRDLKALSEAELGELSEEIREFLVHAVSRTGGHLGP
                     NLGVVELSIALHRVFESPVDRILWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDIIENSHASTALGWADGLAKAHRVQGEKGHVVAVIGDGALTGGMAWEALNNIAAAK
                     DRPLIIVVNDNERSYAPTIGGLANHLATLRTTDGYEKVLAWGKDVLLRTPVVGNTLYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPIDGHDIKAVESALRRAKRFHGPVLVHCLTEK
                     GRGYEPALLHEEDHFHTVGVMDPLTCEPLAPSGGPSWTSVFGDEIVRIGEERDDIVAIT
                     AAMLHPVGLGKFAERFPGRVWDVGIAEQHAAVSAAGLATGGLHPVVALYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGADGASHNGMWDLSVLQVVPGLRIAAPRDAGQLRAQL
                     REAVAVDDAPTLVRFPKESVGPDIPAIGHVGGMDVLHRGERPEVLLVAVGVMAPVCLQA
                     ADLLASRGIGCTVVDPRWVKPVDPALPGLAAEHRLVAVVEDNSRSAGVGSAVALALGDA
                     DVDVPVRRFGIPEQFLAHAKRGEVLADIGLTPVEIAGRISASLAVRDADGTAKENE"
     gene            complement(7198..8325)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="M878_RS56200"
                     /old_locus_tag="M878_06505"
     CDS             complement(7198..8325)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031167.1"
                     /locus_tag="M878_RS56200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06505"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_023545294.1"
                     /transl_table=11
                     /translation="MTAVPLGVPEVPARPVAPRRLSRQIQVGPVAVGGGAPVSVQSMTT
                     TRTSDIGATLQQIAELTASGCQIVRVACPTQEDADALATIARKSQIPVIADIHFQPKYV
                     FAAIEAGCAAVRVNPGNIKQFDDQVKEIARAAKDHGTPIRIGVNAGSLDRRLLQKYGRA
                     TPEALVESALWEASLFEEHDFTDIKISVKHNDPVVMIEAYRQLAESCDHPLHLGVTEAG
                     PAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPAEEVKVGIQILESLGLRQRRLEIVSC
                     PSCGRAQVDVYKLAEEVTAGLDGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQI
                     FVKGEVIKTVPESKIVETLIEEAMKIAERTSPADK"
     gene            complement(8330..9352)
                     /gene="hpnH"
                     /locus_tag="M878_RS56205"
                     /old_locus_tag="M878_06510"
     CDS             complement(8330..9352)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386169.1"
                     /locus_tag="M878_RS56205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06510"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_023545295.1"
                     /sec_met_domain="PF04055 (E-value: 1.4e-17, bitscore: 63.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.8e-08, bitscore: 32.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIKVATYLFEQKLRKRDKFALLVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKKKFVF
                     LCTNALLMRKKMDKFKPSPYFAWAVHIDGLRERHDASVAKEGTFDEAVEAIKEAKRRGF
                     RVTTNSTFFNTDTPQTVVEVLNFLNDDLQVDEMMLSPAYAYEKAPDQDHFLGVQQTREL
                     FKKAFSGGNRAKWRLNQSPLFLDFLEGKVDFPCTAWAIPSYSLFGWQKPCYLMSDGYVP
                     TYRQLLEETDWDKYGRGKDPRCDNCMAHCGYEPTAVLATMGSLKESLRAMRETVSGNRE
                     "
     gene            complement(9358..9999)
                     /locus_tag="M878_RS56210"
                     /old_locus_tag="M878_06515"
     CDS             complement(9358..9999)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431357.1"
                     /locus_tag="M878_RS56210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06515"
                     /product="hypothetical protein"
                     /protein_id="WP_023545296.1"
                     /transl_table=11
                     /translation="MTNQPAAAPLLIACALGIEHLALRTGDRGGADGPVSFLRTGMGPR
                     AAERSVTRQLSGPALADAAVLATGFCAGLAPGMHPGDLVVAEETRDPRGTVACVGTELL
                     VKELVRLLPGRTVHTGPLTGSDHVVRGPERSQLLATGALAVDMESAATLLAAVRGGERP
                     VAAVRVVVDAPEHELVRIGTVRGGISAFRVLRSVLPAFYEWHRSLLLPRR"
     gene            complement(10001..12025)
                     /gene="shc"
                     /locus_tag="M878_RS56215"
                     /old_locus_tag="M878_06520"
     CDS             complement(10001..12025)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676206.1"
                     /locus_tag="M878_RS56215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06520"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_023545297.1"
                     /sec_met_domain="T2TS (E-value: 1.1e-151, bitscore: 505.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGATVPTRAAAASDTTDTAPETAGVPEAAARAARRAT
                     DFLLARQDAQGWWKGDLETNVTMDAEDLLLRQFLGIRDEKTTRAAAMFIRGEQREDGTW
                     ATFYGGPGELSATIEAYVALRLAGDTPGAPHMAKASAWIRERGGIAASRVFTRIWLALF
                     GWWKWEDLPELPPELIYFPAWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDEL
                     HSDPADPNPAKPLAPVASWDGAFQRLDKALHQFRKVVPRRLRRAAMNSAARWIIERQEN
                     DGCWGGIQPPAVYSVIALHLLGYDLEHPVMREGLASLDRFAVWRKDGARMIEACQSPVW
                     DTCLATIALIDAGLPADHPQLVRAADWMLGEEIVRPGDWAVKRPGLPPGGWAFEFHNDN
                     YPDIDDTAEVALALRRVRHHDPERVDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPN
                     RLPFCDFGEVIDPPSADVTAHVVEMLAAEGLAHDPRTRRGIEWLLAEQEPNGSWFGRWG
                     VNYVYGTGSVVPALTAAGLPGSHPAIRRAVAWLESVQNDDGGWGEDLRSYRYVKEWSGR
                     GTSTASQTAWALMALLAAGEQDSKAVERGIRWLADTQREDGTWDEPYFTGTGFPWDFSI
                     NYHLYRQVFPLTALGRYLHGDPFERDLLARKPQAEAKVS"
     misc_feature    12129..12144
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.62"
                     /tool="antismash"
     misc_feature    complement(12132..12147)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.27"
                     /tool="antismash"
     gene            complement(12140..13273)
                     /locus_tag="M878_RS56220"
                     /old_locus_tag="M878_06525"
     CDS             complement(12140..13273)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656372.1"
                     /locus_tag="M878_RS56220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06525"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_078630204.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.1e-56, bitscore:
                     191.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLEAAAGPRTPGTATRGETVPTVPPASTPVPRAAVDVTALLERG
                     RTLATPVLRAAVDRLASPMDTVAAYHFGWIDAAGNPADGDGGKAVRPALAVLSAQVTGA
                     APEVGIPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALAN
                     EVLLELGTVEAGRATRRLTTATRALIDGQAQDISYEHRDRVSVEECLEMEGNKTGALLA
                     ASSSIGAVLGGADDATADALEKYGYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRK
                     KSLPVVAALAAGGPASEQLGEILAADAKSSDFENFSEEEFAARAALIEQAGGRDWTAGE
                     ARRQHIIAIEALDAIDMPDRVRDSFTALADFVVVRKR"
     gene            complement(13273..14706)
                     /gene="hpnE"
                     /locus_tag="M878_RS56225"
                     /old_locus_tag="M878_06530"
     CDS             complement(13273..14706)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546810.1"
                     /locus_tag="M878_RS56225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06530"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_023545299.1"
                     /transl_table=11
                     /translation="MSDGSRPAPAHGTARDEGAAGRGAVVVGGGLAGITAALALADAGV
                     RVTLLEGRPRLGGLAFSFQRGELTVDNGQHVYLRCCTAYRWFLDRIEGAALAPLQDRLD
                     VPVVDVAKPEGRRLGRLRRDPLPVPLHLGRSLAAYPHLSLAERAAVGRAALALKGLDLA
                     DPALDTQDFGSWLAAHGQSARAVEALWDLVGVATLNAVAGDASLGLAAMVFKTGLLSDP
                     GAADIGWARVPLGELHDRLARKALDSAGVRTEVRTRVTSVSTNENGTWSVQVPGERLET
                     DAVVLAVPQREAHGLLPSGALDAPERLLGIGTAPILNVHVVYDRKVLARPFFAALGTPV
                     QWVFDRTDASGLGAGQYLALSQSAAQDEIDLPVADLRERYLPELERLIPGTRGAEVRDF
                     FVTRERTATFAPVPGVGRLRPGARTNAPGLYLAGAWTATGWPATMESAVRSGVSAADAA
                     LSTLGRPRPRHLFEFEEAA"
     gene            complement(14831..15793)
                     /gene="hpnD"
                     /locus_tag="M878_RS56230"
                     /old_locus_tag="M878_06535"
     CDS             complement(14831..15793)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972236.1"
                     /locus_tag="M878_RS56230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06535"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_031224275.1"
                     /sec_met_domain="phytoene_synt (E-value: 8e-55, bitscore:
                     185.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.9e-68,
                     bitscore: 229.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVDSPSHVSAPVLAAYSYCETVTGQQARNFAYGIRLLPTPKR
                     RAMSALYAFSRRVDDIGDGDLAGGVKLKRLEDTRALLARVRDGEVEEDDTDPVAVALAH
                     AAHAFPIPLGGLDELIDGVQMDVRGETYETWDDLKVYCRCVAGAIGRISLGVFGTEPGA
                     RGAERASEYADTLGLALQLTNILRDVREDAEGGRTYLPADDLAKFGCSAGFDGPTPPEG
                     SDFAGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLR
                     GRVSLPGREKAYVAVRGLSGLDTRHVTRHVSPRSVRRRA"
     gene            complement(15790..16686)
                     /gene="hpnC"
                     /locus_tag="M878_RS56235"
                     /old_locus_tag="M878_06540"
     CDS             complement(15790..16686)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042802.1"
                     /locus_tag="M878_RS56235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06540"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_023545301.1"
                     /sec_met_domain="phytoene_synt (E-value: 2e-39, bitscore:
                     134.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.4e-41,
                     bitscore: 141.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATETAPHLERATLDKATSENFPVAPFFLPRAWRDDLMAVYGFA
                     RLVDDIGDGDLAPGGADARALGVSPAEAEDRLLLLDAFEADLRHVFDGTPSHPLLRRLQ
                     PTVRRRSLTPEPFLGLIAANRQDQLVTRYETYDDLLAYCELSANPVGRLVLDVSGTSTP
                     ERIRLSDAICTALQIVEHLQDVAEDLGRDRIYLPAEDMKRFHVQETDLGAKTAGASVRA
                     LVAYEAQRARDLLNEGAPLVGSVHGRLKLLLAGFVAGGRAAIRAIAAAEYDVLPGPPRP
                     GKVQLLREAGVILRGEG"
     gene            complement(17047..17847)
                     /locus_tag="M878_RS56240"
                     /old_locus_tag="M878_06545"
     CDS             complement(17047..17847)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568727.1"
                     /locus_tag="M878_RS56240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06545"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_023545302.1"
                     /transl_table=11
                     /translation="MAERNAGQATEAPEERRPTVIADELHIVYRVNGAKTGKGSATAAL
                     SRIMKRGGERGVRRVHAVRGVSFVAYRGEAIGLIGSNGSGKSTLLRAIAGLLPAEKGEV
                     YTDGQPSLLGVNAALMNDLTGERNVILGGLAMGMSREQIKERYQDIVDFSGINEKGDFI
                     TLPMRTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQKRSEERIRELRKEAGTV
                     FLVSHNNKSIRDTCDRVLWLERGELRMDGPTEEVLKEYEKFTGK"
     gene            complement(17840..18769)
                     /locus_tag="M878_RS56245"
                     /old_locus_tag="M878_06550"
     CDS             complement(17840..18769)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="M878_RS56245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06550"
                     /product="ABC transporter permease"
                     /protein_id="WP_023545303.1"
                     /transl_table=11
                     /translation="MSHTTHDGGVAKSAIPPPDEGLTAAQLAAKYGLAVSGARPSLAEY
                     VRRLWGRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNAAVYYFIFGVILHASRGLS
                     QDVYIPFLVTGVFVFTFTQSSVMSGVRAISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSMIVMFVVAIGFGSYPSPAWLLIVPVLLLQFLFNTGLALIVARMGAKTPDLAQLMPFI
                     LRTWMYTSGVMFSISKMMEGRSEIAVRLLQVNPAAVYMDLMRYALIDGYGAANLPPHVW
                     AIALFWAVLVFAGGFVYFWQAEERYGRG"
     gene            complement(18829..19701)
                     /locus_tag="M878_RS56250"
                     /old_locus_tag="M878_06555"
     CDS             complement(18829..19701)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="M878_RS56250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06555"
                     /product="glycosyltransferase"
                     /protein_id="WP_023545304.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.2e-13,
                     bitscore: 48.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGAVIITMGNRPEELRALIDSVAKQDGDPVEVVVVGNGSPVPD
                     VPDGVRTVELPENLGIPGGRNVGIEAFGPSGRQVDILLFLDDDGLLARHDTAELCREAF
                     AADPELGIVSFRIADPDTGETQRRHVPRLRASDPMRSSRVTTFLGGANAVRTRVFAEVG
                     GLPDEFFYAHEETDLAWRALDAGWMIDYRSDMVLHHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPAPLVPVYLGVWMLLTLLRRPSRPALRAWFGGFREGWTTACGPRRPMRWRTVWRL
                     TRLGRPPVI"
     gene            complement(19707..20486)
                     /locus_tag="M878_RS56255"
                     /old_locus_tag="M878_06560"
     CDS             complement(19707..20486)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413838.1"
                     /locus_tag="M878_RS56255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06560"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_078630205.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREVSLRIDRYLV
                     TTRVTPNQLTYLMTVCGVLAAPALLVPGIWGAVLGVVATQLYLLLDCVDGEIARWKKQY
                     SLNGVYLDRVGAYLTDAAVLVGLGLRAADLWGSGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQAGKPPVQEAAAEPRSSGMALARRAAAALRFHRLILGIEASLLILVLAIVDQ
                     ARGDLFFTRLGTAVLAGIALLQTLLHLVSILASSRLK"
     gene            complement(20464..21525)
                     /locus_tag="M878_RS56260"
                     /old_locus_tag="M878_06565"
     CDS             complement(20464..21525)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="M878_RS56260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06565"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_023545306.1"
                     /sec_met_domain="Fe-ADH (E-value: 8.4e-22, bitscore: 76.5,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.4e-06, bitscore:
                     26.7, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLTRLIPSPVVVDIRPGALDDLAGVLADERIAQSGRLAVAVSG
                     GSGAKLRERIAPSLPGATWYEVGGGTLDDAIRLAGEMKSGHYDAVVGLGGGKIIDCAKF
                     AAARVGLPLVAVPTNLAHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPARF
                     VRAGIGDAISNINAVADWELSNRVTGEKIDGLAAAMARQAGEAVLRHPGGIGDNGFLQV
                     LAEALVLSGISMSISGDSRPSSGSCHEINHAFDLLFPKRAAAHGEQCGLGAAFAMYLRG
                     AHEEAVHTAFVLRRHGLPVLPEEIGFTLDEFVRAVEFAPETRPGRYTILEHLDLKTNQI
                     KDIYADYVKAIGS"
     gene            complement(21513..22265)
                     /locus_tag="M878_RS56265"
                     /old_locus_tag="M878_06570"
     CDS             complement(21513..22265)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="M878_RS56265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06570"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_023545307.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.8e-09, bitscore:
                     37.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDSLPKALVPVGPAGIEDSITVLDLTLG
                     NFAEIGLTEVAIIVGYRKEAVYERKEALEAKYGLKLTLIDNDKAEEWNNAYSLWCGRDA
                     LKDGVILANGDTVHPVSVEKTLLAARGEGKKIILALDTVKSLADEEMKVVVDADKGMTK
                     ITKLMDPAEATGEYIGVTLIEGDAAPDLADALKTVWETDPQQFYEHGYQELVNRGFRID
                     VAPIGDVQWVEIDNHDDLAKGREIACRY"
     gene            complement(22262..24061)
                     /locus_tag="M878_RS56270"
                     /old_locus_tag="M878_06575"
     CDS             complement(22262..24061)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="M878_RS56270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06575"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_023545308.1"
                     /transl_table=11
                     /translation="MSTAIVTGQPVPGSSLENDLRALGFDVRVAADAAEAETLLAAAPA
                     GERVALVDARFVGHPHALRLGLTDPRFPLSAVPGAVTAQRAARQELTRAVARETSAGGG
                     TALAVDSLADRIVTALDADGCAVHRPELGSLVAAVPADPQARNEARQAVAAVDDEAVRL
                     KSAVKSRDGFFTTFFISPYSRYLARWCARRGLTPNQVTTASLLTALIAAGCAATGTRAG
                     FIAAGVLLIASFVLDCTDGQLARYALKYSTLGAWLDATFDRAKEYAYYAGLALGAAHGG
                     DDVWALALGAMVLQTCRHTVDFAFNEANHDATANTSPTAALSDKLDSVGWTIWLRRMIV
                     LPIGERWAMIAILTAATTPRITFYVLLIGCALAATYTTAGRVLRSLTRKARRTGRAAQA
                     LADLADSGPLTEAVRRVLKRGLPGLAVPAVAFAGGAAVVACSAFTDHGSVLPVIGALVY
                     VLTSALAVARPLKGALDWLVPPFFRAAEYGTVLALAGKAGVNGALPAAFGLVAAVAYHH
                     YDTVYRIRGDAGAPPAWLVRAIGGHEGRTLLVTVLAAVLTAPQFTVALTVLAVAVALVV
                     LVESIRFWVSAGAPAVHDEGEPA"
     gene            <24457..24699
                     /locus_tag="M878_RS56275"
                     /old_locus_tag="M878_06580"
                     /pseudo=""
     CDS             <24457..24699
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431370.1"
                     /locus_tag="M878_RS56275"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06580"
                     /product="UDP-glucose 4-epimerase GalE"
                     /pseudo=""
                     /transl_table=11
                     /translation="DLTLNIGRGEGVSVRELITVIGEVTGDHREPLVEGRRPGDAPRSV
                     ASAERAGKELGRRAGRGVREMVESAWRGWQRHHGR"
     misc_feature    complement(24788..24802)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            24877..25818
                     /locus_tag="M878_RS56280"
                     /old_locus_tag="M878_06585"
     CDS             24877..25818
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="M878_RS56280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06585"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_023545310.1"
                     /transl_table=11
                     /translation="MGAGHDHGHAHSHAPATGTAAAAYRGRLRIALGITLTIMLVEIVG
                     GLLADSLALIADAAHMATDAVGLGMALLAIHFANRPPSTNRTFGYARAEILAALANCVL
                     LLGVGGYVLYEAVERFVTPADTRGGLMVVFGLIGLVANSVSLTLLMRGQKESLNVRGAF
                     LEVAADALGSGAVLVSGAVILTTGWQTADPVASIAIGLMIVPRTLKLLRETLDVLLESA
                     PKNVDMAEVRAHILALDGVEDVHDLHAWTITSGMPVLSAHVVVSSDTLSAIGHEKLLHE
                     LQGCLGDHFDVEHCTFQLEPGGHAEHEARLCH"
     gene            25993..26586
                     /gene="idi"
                     /locus_tag="M878_RS56285"
                     /old_locus_tag="M878_06590"
     CDS             25993..26586
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129457.1"
                     /locus_tag="M878_RS56285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_06590"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_023545311.1"
                     /transl_table=11
                     /translation="MPITPATAKHSSSNGTEEAILLELVDEKGVTIGTAEKLAAHQPPG
                     QLHRAFSVFLFDEQGRLLLQQRALGKYHSPGVWSNTCCGHPFPGEAPFAAAARRTFEEL
                     GVSPSLLAEAGRVRYNHPDPASGLVEQEYNHLFVGLVQAPLAPDPEEVGGTAFVTAAEL
                     TERHERDPFSAWFMTVLDAARPAIRELTGLSAGW"
ORIGIN
        1 gaaccgcagc gtgctgaccc ggccgttgag ctgggtgttc gggctgtcgg tgacccaggc
       61 ggccatcacg cgcgcgggat ggatctggct gaagccatgc tggatggcga gccggtcgag
      121 cgggtcggtg ttgtcggagg tccacacctg gtcggtacgg ctcagcaccc cgaggtcgat
      181 gcggccgccg ccgcccgagc aggactcgaa ggcgaccgag gggtgggccg cgcggagccg
      241 gtccagcagg gcgtacaggg cgcggacgtg gtccacccac aggcgctgcg gatacggctc
      301 accgggccag ccgacgtcgg tgaagcagcg gttgaagtcc cacttcacat agtcgatcgg
      361 cgcgctggag agcagggtgt ccagctgctc ccagaggtac tcctggacgt cctcgcgggc
      421 gaggttgagg acgagttggt tgcgcagttc cgtccgcttg cgccccggct ggtactgcac
      481 ccagtcggga tgcgcgcggt acaggtcgct gtccgggttg accatctcgg gctcgaccca
      541 gatgccgaac tgcataccga ggccgtgcac ttggtcggcg aggggcttca ggccctgtgg
      601 gaagcggtcg gggttggggg tccagtcacc gagcccggcg cggtcgctgg tgcgggcgcc
      661 gaaccagccg tcgtccacca cgaaaagctc cacgccgatg ccggcggccc gtcgggcgag
      721 cgcgagctgc tgctcctcgg agatgccgaa gttcgtcgcc tcccaggagt tgaagagcac
      781 cggccggtcc cgctccgcgt ccgggatgac gtacgcgcgc tggtaggcgt gccaggtgcg
      841 gctagcgccg ccgaaaccgc cgccgctcca caggcccgcg aagacggggg tggtgtacga
      901 ctccccgggc tgaaggagca gcaggcccga gtcgtcgtag ccggcgccgc cggtgatctg
      961 cacgcgcgcg tccgggagtt gggcgaccgc gatacgccag gagccggacc agccgagcgc
     1021 acagccgtag acctcgccgc gctcctcggt ggcgtcggtg tccagcgcca cccagggcag
     1081 gtgctggtgg ccggtgtgcc cgcggcggct gccgatgacc ttctcgccgt aggtgagcgg
     1141 ggcggtggtg aggcgggact cggcggccca gcggccgtgc agctgggaca gccgccagcc
     1201 gtcgcggtcg ggcagggtcc aggtggccgc gtcggctcgc agcagctcca cgcgcgcgtg
     1261 cgtgtcgttc gccaccgtga cccagcgctc gacgacgtca ccgcgcatcc ggtagtgcag
     1321 ggtgacggcc aggccgtcgt cgtcgaagcg cagccgcaac tcgtccgcct ccgtgtcgta
     1381 ggcctggaat ctccactccg tgccgcggcg ctcgtcgctg cgcacggaca gggcggggcg
     1441 gacgaagcgt gggccgccct cgacggggta ctcctcgcgg ccgtcgagcg gggactcgaa
     1501 gggccagtag ccgggcagcg gctccttggc cagggcctgc gcgtccgcga gggcgacacg
     1561 tggcccccag tgcaggtgga gcagttcgtc cgcgtcggtg agatgcaggg cataactgct
     1621 ggtgggcccc gagaggagcc aggtacgacc gtcttcggcg atgtccacca cgtaagacct
     1681 cacaggtgtc aacagatccg ctcaagtgcc aacatcatta ggccgcgccg ccgcaggtgc
     1741 aatgcctgtg gacaactcct tgcccgagga aaccggtgtc gtatggtcga cagagcgccc
     1801 gccgacgagc cgcgacggcg gggcccgacc gggaggagcc cccgtgacgc agcaggtccc
     1861 gtcgaccgaa ccggagctgg ccggagtgcg caatttccgc gacgttggcg gactgccgac
     1921 catggacgga cggcgggtgc ggcacggggt gctgttccgc agcggacacc tggcgcacgc
     1981 gaccgaggac gatgcggcat tcctcacctc gctgggcctg cacacgatct tcgacttccg
     2041 caacgcggcc gaccagaagc tggagggccc ggacgtcgag ctgcccggcg tgcggaatgt
     2101 gaacctgccg ctgagcgacc cggcggacgg cgccgagttc tggaagatgg tccgcgacgg
     2161 cgacctcgac cagctgcgcg gcatcctcgc cgacggcaag ggtgcgaccc ggatgatcgc
     2221 ctcgtaccgg tcgatcgtca aggagcgcac caccgagcac tcccaggtcc tgcgcgcgct
     2281 caccgaggac agcgtgcccg ccctgatgca ctgcgcggcc ggcaaggacc gcgcgggcat
     2341 ctccatagcc gtgacactcc tcgcgctggg cgtggagcgc gacgcgatcg tcgccgacta
     2401 tctggagtcc aacgccaagc accggcgcta caaggtccgc cgcagcggca gcacggaggg
     2461 tgcctacacc cccgaggtca tggagttgct cagcccgctc ttcgacgccc gcgccgagta
     2521 cctccacgcg gcgttcgaga ccatcgagca gacctggggc ggcgtggaca cgtacctgga
     2581 gcagggcctc gccctcaccc cggctgcccg cgaccacctg cgcgaacgcc tgctggactg
     2641 agcggacacg acagcgccgg cgtgtcgggc ctacgcccgt gagttcaccg gcccgcatcc
     2701 gcccgtgatt ccaccggccc ggccgcctca gcccttcgcg cccaccgcga acagcaagta
     2761 caggaacccg gccaggacat ggccgagggc gatgtagatg atcaggcgga tccacaggga
     2821 acgggggaac ttcgtctcga agtcgctcat ggcagctctc gggtcagcgg ccccaggcac
     2881 agcgtggccg tggggctctg cagcagggtg tggacgaaca gcagctcgac gccgtcgtgg
     2941 tcctcggcgg cgaggcggtg cggggtgagc gagtcgaagt gagcgctgtc gccgggcccg
     3001 agcagatgcg cggtgtcacc gaggcgcagc cgcagccggc cccgcaggac atagagccac
     3061 tcctcgccgg gatggacgcg cacgatgtcg ccctgcgagc cgtacggcac ccgcacgcgg
     3121 agggcgtgca tggcccggcc gggcgccccg gcctggaagt acgtccagcc gcccgcccgg
     3181 gtcggctcca tgtcgccggc ccgcacgatc gcgtcccggt cggcgaccgt ctcgcccagc
     3241 agctcggaga cggtcgtacc gtagatgcgg gcgagagcca gcagcatcgg cagcgacggc
     3301 tgccgccggc ctgtctccag ccgggacaga tgggccggcg agagcccggc ggcgcgggcc
     3361 gcggcctcca gagtgaggcc ggcgcgccgg cgcagtgccc gcaactgcgg tgcgacggcc
     3421 gtcagctcgt cacccggacc cgccggtggg ccggcgtctg aggcgttcat gccttcattc
     3481 agcccgatgt ttgcccattc ggcaattttc ttgccttaga ggcaaagcag caagctccct
     3541 gccttgatag gctcgaccca ggatttgaac acgttcaaaa gtggggttcg catgtccgcc
     3601 cgcatcacgc ccgaccgagc cgacacaccc gccgtcgccc tcggccccgt atccctcgtg
     3661 ctggggatcg tcgccgctgt cggcgcatgg cccgctctta cgctcgccct gctcccgctg
     3721 tgcctcatcg ccggcgggct ggccgtcacc ttcggcctca tgggcatgta ccacgccggc
     3781 cgcggcgtcg gcagcccatg gaccgcggcc acgggaaccg tcctcggcgc ggccggcctg
     3841 accgctccct tcatcctcgt cgtcctgctc tccgcctgac gctcagcggc ccgccaccgc
     3901 ctgcttgatc agggtcttgc cgaagtccca catcaggccg ccgccgctgt gcgcgtcgtc
     3961 catcacggcg gtgaaggcgt ccacgaaccg gtcgacatcc gcctcgtcga tgatcaacgg
     4021 cgggatcagc ttgatcacct ccagatggtc gccggagacc tgggtgagga tccggtgccg
     4081 ctgcagcagc ggcacgacga ccatctgcgc gaacaagccc ttgcgcgccg cctgcagcat
     4141 ggtccagcgg ctgcgcagtt tcagcgagga cggcttgccg aactcgatgc cgatcatcag
     4201 gccccggccg cggatgtcgg cgaggagttc gtacttgtcg accagcccgg tcagccggga
     4261 cttcagcagt tcaccggtgc tgcgcacacc cgcgacgatc tgctcgttct ccatggccga
     4321 cagcacggcg aggccgcacg ccatcgccgg ggcgttggag ccgaagctgg ccgagtggac
     4381 cagaacgcgg tccatggacg agtagacctt cttgaagatc cagtccttgc cgagggtggc
     4441 gccgaccggg acgtacccgc cggacagcgc cttggccacg cacaccaggt cgggttcgac
     4501 gccgtcctcg tgctggtagg cgtagaagtc gccggtgcgg ccgagaccgg tctgcacctc
     4561 gtcggcgatg agcagcgcct tgtgccggtg cagcagctcc tgggcggcgc gcagatagcc
     4621 gggcggggcc tcgtgcaccc ccttgccctg gatgggctcc acgatcaggg cggccacgtc
     4681 acccttcttc aactcccgtg ccagggcgtc gagatcgccg aggggtacgg cggtgtcggg
     4741 cagcagcggg gcgaagccgt cgcggaagcc gccctcgccg ttgaccgaca gggaaccggt
     4801 ggtcaggccg tggaaggcgt gatcgcagta gaggacacgg ggcttgccgg tggcgtaccg
     4861 ggcgaacttc agggccgtct cgacggcctc cgtgccgctg ttgccgaaga acacccggtc
     4921 caggtgcggg ctgtgggcga gcagcctttc ggcgagcagg ccgggcagcg gctggcagtc
     4981 gaaccgggtc aggtcggcga ggttcaggtc gagcacgtcg tgcagcgcct tgcggacgac
     5041 cgggtgatgg cggcccaggc ccatcacccc gaacccggcg agcatgtcca ggtagtcgtt
     5101 gccgtccgcg tcgtagaagt gggcgccctc ggcccgctcg tagaccctgt cgaagccgat
     5161 ggtgtgcagc atgcgcggga gctgcgggtt gagatacttc gcgtgcagct cgtagcgttc
     5221 ggtaccgcgc tcggcgagca gggcgccgag gtcgaactcc gtgctcattc attctccttg
     5281 gctgtgccgt ccgcgtccct gacggccagg ctcgcgctga tccgcccggc gatctcgacg
     5341 ggcgtgagac cgatgtcggc cagcacctcg ccgcgcttgg cgtgggcgag gaactgctcc
     5401 gggatgccga accgccgtac cggcacgtcc acgtcggcgt cgccgagggc cagcgccacg
     5461 gccgaaccga cgcccgcgga gcggctgttg tcctccacga cggccaccag ccggtgttcg
     5521 gcggcgaggc ccggcagcgc ggggtcgacg ggcttgaccc accgggggtc caccaccgtg
     5581 cagccgatgc cgcgggacgc cagcaggtcg gcggcctgta ggcagaccgg tgccatcacg
     5641 ccgacggcca ccagcagcac ctcggggcgt tcgccgcggt gcagcacgtc catgccgccg
     5701 acgtgtccga tcgccgggat gtccgggccg acggactcct tcgggaagcg gaccagcgtg
     5761 ggcgcgtcgt ccacggcgac ggcctcgcgc agctgggcgc gcagctggcc ggcgtcgcgc
     5821 ggcgcggcga tcctgaggcc ggggacgacc tggaggacgg acaggtccca cataccgttg
     5881 tgggaggcac cgtcggcgcc ggtgacaccg gcccggtcga ggacgaaggt gaccccgcag
     5941 cggtgcagcg cgacgtccat cagcagctgg tcgaaggcgc gattgaggaa ggtggcgtag
     6001 agggcgacga ccgggtgcag cccgccggtg gcgaggccgg ccgcggagac ggccgcgtgc
     6061 tgctcggcga tgcccacgtc ccacacgcgg ccggggaagc gttcggcgaa cttgccgagg
     6121 ccgaccgggt gcagcatggc cgccgtgatg gcgacgatgt cgtcgcgttc ctcgccgatg
     6181 cggacgatct cgtcgccgaa caccgaggtc caggacgggc cgccggacgg cgcgagcggt
     6241 tcgcaggtca gcgggtccat cacgccgacg gtgtggaagt ggtcctcctc gtgcaggagg
     6301 gcgggctcat agccgcggcc cttctcggtg aggcagtgga ccaggaccgg gccgtggaag
     6361 cgtttcgcgc ggcgcagcgc cgactcgacg gccttgatgt cgtgcccgtc gatcgggccg
     6421 acgtacttca ggcccaggtc ctcgaacatg ccctgcgggg cgaaggcgtc cttgaagccc
     6481 ttcttcgccc cgtgcaggga ctcgtagagg gtgttgccga cgacgggtgt gcgcagcagt
     6541 acgtccttgc cccaggcgag gaccttctcg tagccgtcgg tggtgcgcag ggtggccagg
     6601 tggttggcga ggccgccgat ggtcggcgcg taggagcgtt cgttgtcgtt gacgacgatg
     6661 atcagcgggc ggtccttggc ggccgcgatg ttgttcagcg cctcccaggc catgccgccg
     6721 gtcagcgcgc cgtcgccgat gacggcgacc acatggccct tctccccctg cacccggtgg
     6781 gccttggcga ggccgtcggc ccagccgagc gcggtggagg catgactgtt ctcgatgatg
     6841 tcgtgctcgg actcctcgcg cgaggggtag ccggacagtc cccccttgcc gcgcagcttg
     6901 gagaagtcct gacgcccggt cagcaacttg tggacatagg actggtggcc ggtatcccac
     6961 aggatgcggt cgaccggtga ctcgaagacc cggtggagcg cgatggacag ttccaccacc
     7021 cccagattgg gcccgagatg accgccggtc cgcgacaccg cgtgcaccag gaactcgcgt
     7081 atctcctcgg acagttcgcc gagttccgcc tcggacagcg ccttcaggtc gcgtggtccc
     7141 cggatgttct ccagaatggt cacgtgggcc ccctctcggt ccgtgctcta cctcaactca
     7201 cttgtctgcg gggctcgttc gctcggcgat cttcatcgcc tcctcgatga gcgtctccac
     7261 gatcttcgac tcgggtacgg tcttgatgac ctcgcccttg acgaaaatct gcccctttcc
     7321 gttgcccgag gcaactccca ggtcggcctc gcgggcctcg cccggaccgt tcaccacaca
     7381 ccccatcacc gcgaccctga gcggcacttc catgccgtcc aggcccgccg tgacctcctc
     7441 ggcgagtttg tagacgtcga cctgggcccg gccgcaggag gggcaggaga cgatctccag
     7501 ccgccgctgc ctgaggccga gggactccag gatctggatg ccgaccttga cctcctcggc
     7561 cggcggcgcg ctcagcgaga cgcggatcgt gtcgccgatg ccccgggaca gcaacgcccc
     7621 gaaggccacg gccgacttga tcgtgccctg gaacgcgggg cccgcctcgg tgacccccag
     7681 gtgcagcggg tggtcacagc tctcggcgag ctgccggtac gcctcgatca tcacgaccgg
     7741 gtcgttgtgc ttgacggaga tcttgatgtc cgtgaagtcg tgctcctcga agagcgaggc
     7801 ctcccacagc gcgctctcga ccagcgcctc cggggtggcc ctgccgtact tctgcagcag
     7861 tcgccggtcg agggaaccgg cgttgacgcc gatccggatc ggtgtgccgt ggtcctttgc
     7921 ggcgcgcgcg atctccttca cctggtcgtc gaactgcttg atgttgcccg gattgacccg
     7981 gacggcggcg cacccggcct cgatggcggc gaagacgtac ttgggctgga agtggatgtc
     8041 cgcgatcacc gggatctgcg actttcgggc gatggtggcg agggcgtccg cgtcctcctg
     8101 cgtggggcag gcgacgcgga cgatctggca gccggacgcg gtgagttccg cgatctgctg
     8161 cagggtggcg ccgatgtcgg acgtacgggt cgtcgtcatc gactgcaccg acaccggggc
     8221 tccgcccccg accgccaccg gcccgacctg gatctgccgc gacagccgcc gcggtgcgac
     8281 cgggcgggcc ggtacctcgg gaacgcccaa gggaacggcg gtcatcgtgt cactcccggt
     8341 ttccggagac ggtctcgcgc atggcccgca gcgactcctt cagggagccc atggtggcga
     8401 ggacggcggt gggttcgtag ccgcagtgcg ccatgcagtt gtcgcagcgc gggtccttgc
     8461 cgcggccgta cttgtcccag tcggtctcct ccagcagctg ccggtacgtg ggcacgtagc
     8521 cgtcgctcat caggtagcag ggtttctgcc agccgaacag cgagtagctc gggatcgccc
     8581 acgcggtgca cgggaagtcg accttgccct ccaggaagtc caggaagagc gggctctggt
     8641 tgagccgcca cttcgcgcgg ttgccgcccg agaatgcctt cttgaacagt tcccgggtct
     8701 gctggacgcc gaggaagtgg tcctggtcgg gggccttctc gtaggcgtag gcgggcgaga
     8761 gcatcatctc gtcgacctgc aggtcgtcgt tgaggaaatt gagcacctcg acgacggtct
     8821 gcggggtgtc cgtgttgaag aaggtggagt tggtggtcac ccggaagccg cgccgcttgg
     8881 cctccttgat cgcctccacc gcctcgtcga aggtcccctc cttcgccacc gaggcgtcgt
     8941 gccgctcccg cagcccgtcg atgtgcacgg cccaggcgaa gtagggcgag ggcttgaact
     9001 tgtccatctt cttgcgcatc agcagcgcgt tggtgcacag gaagacgaac ttcttcttcg
     9061 ccaccagctg ccgcacgatc tcgtcgatct gcggatgcat cagaggttcg ccgccggcga
     9121 tcgagaccat cggcgcaccc gactccagga ccgcgcccac ggcctgcgcc acgggcatgc
     9181 gctgcttgag cacgcccgcc gggtgctgga tcttgccgca gccctcgcac ttgaggttgc
     9241 acgcgaacag cggctccagc tcgaccagca gagcgaactt gtcgcgcttc ctgagcttct
     9301 gttcaaacag atacgtagcg accttgatgg tctgacgcaa cggcatggcc atctggctca
     9361 cctccggggg agcaacaaag aacggtgcca ttcataaaat gcgggaagaa cggaacgaag
     9421 aacgcggaaa gcagatattc caccgcgcac cgtgccgatc cggacgagtt cgtgttctgg
     9481 ggcgtccacc accacccgta cggccgcaac cgggcgctcg ccgccgcgga cggcggcgag
     9541 gagcgtggcc gccgactcca tgtcgaccgc gagcgcgccg gtcgcgagca gctgggaccg
     9601 ctcggggccg cgcaccacgt ggtcggatcc ggtgagcggc ccggtgtgga ccgtgcgtcc
     9661 gggcagcagg cgcacgagtt ccttgaccag cagctcggtg cccacgcagg cgacggtgcc
     9721 gcgcgggtcc cgggtctcct cggcgaccac caggtcgccg ggatgcatgc cgggcgcgag
     9781 cccggcacag aagccggtgg ccagtacggc cgcgtcggcc agcgccgggc cggagagctg
     9841 ccgggtgacg gaccgttccg ccgcacgggg ccccatgccc gtacggagga aggaaaccgg
     9901 cccgtccgcc ccgcccctgt cccccgtgcg cagggccaga tgctcgatgc cgagcgcgca
     9961 ggcgatcagc agcggggcag ctgcgggctg gttggtcaat tcagctcacc ttggcctcgg
    10021 cctgcggttt cctcgcgagc agatcgcgct cgaaggggtc gccgtgcaga taccggccga
    10081 gcgcggtgag cgggaagacc tgccggtaca ggtggtagtt gatggagaag tcccagggga
    10141 agccggttcc ggtgaagtac ggctcgtccc aggtgccgtc ctcccgctgg gtgtcggcca
    10201 gccagcggat gccgcgctcg acggccttgg agtcctgctc cccggccgcg agcagcgcca
    10261 tcagcgccca cgcggtctgc gaggcggtcg aggtgccccg gccgctccac tccttgacgt
    10321 acctgtagga gcgcaggtcc tcgccccagc cgccgtcgtc gttctgcacg ctctccagcc
    10381 aggccacggc ccgccggatc gccgggtgcg agccgggcag accggcggcg gtcagtgcgg
    10441 ggacgaccga cccggtgccg tagacgtagt tgacgcccca gcggccgaac cacgagccgt
    10501 tcggctcctg ttcggcgagc agccactcga tgccgcgccg ggtgcgcggg tcgtgtgcga
    10561 gtccctcggc ggcgagcatc tccacgacgt gcgcggtgac gtccgccgac ggcgggtcga
    10621 tgacctcacc gaagtcgcag aacggcagcc ggttcgggaa cgggctggtg ttgtcgacgt
    10681 cgaaggcgcc ccacgcgccg ttcttcgact gcatccccag gttccagcgc acggcgcgcc
    10741 cgatggcccg gtccacgcgc tcggggtcgt ggtgccggac ccggcgcagt gcgagggcga
    10801 cctcggcggt gtcgtcgatg tcggggtagt tgtcgttgtg gaactcgaac gcccagccgc
    10861 ccggcggcaa cccgggacgc ttgacggccc agtcgccggg ccgcacgatc tcctcgccca
    10921 gcatccagtc ggccgccctg accagttgcg gatggtcggc gggcagcccg gcgtcgatga
    10981 gcgcgatggt ggcgagacag gtgtcccaca ccggggactg gcaggcctcg atcatccggg
    11041 caccgtcctt gcgccagacg gcgaaacggt ccagcgaggc gaggccctcg cgcatcacgg
    11101 gatgttcgag gtcgtagccg agcaggtgca gggcgatgac cgagtacacg gccgggggct
    11161 ggatgccgcc ccagcagccg tcgttctcct gccgctcgat gatccagcgg gcggcggagt
    11221 tcatcgccgc cctgcggagc cggcgtggga cgaccttgcg gaactggtgc agcgccttgt
    11281 ccagacgctg gaaggcaccg tcccaactgg ccaccggagc aagcggcttg gccgggttgg
    11341 ggtcggccgg gtcgctgtgc agctcgtcca gcgggaaggg cgcggggcgc accgggcgct
    11401 tggccgagac gatggtcagc ggcacgatgg tctgccgggc ccagcagccg aagtcgtaga
    11461 tgttgagcgg catccaggcc gggaagtaga tgagctccgg cgggagttcg ggcaggtcct
    11521 cccatttcca ccagccgaac agggcgagcc agatccgggt gaacacccgg gaggcggcga
    11581 taccgccgcg ctcgcggatc caggcggaag ctttcgccat gtgcggggcg ccgggcgtgt
    11641 cgccggccag gcgcagggcg acgtaggcct cgatggtggc ggacagttcg ccgggcccgc
    11701 cgtagaaggt cgcccaggtg ccgtcctcgc gctgctcgcc gcggatgaac atcgcggcgg
    11761 cccgcgtggt cttctcgtcg cggattccca ggaactgacg gagcagcagg tcctcggcgt
    11821 ccatcgtgac gttggtctcc aggtcgccct tccaccagcc ctgggcgtcc tgccgcgcga
    11881 gcaggaagtc ggtggcgcgc cgcgcggcgc gagcggcggc ttctggtacc ccggccgtct
    11941 cgggggcggt gtcggtggtg tcgctggccg cggcagcgcg ggtcggcaca gtcgccccgg
    12001 tgcttccgtc ggtcgtcgct gtcatggctt ccccttcgtg cagtcgtgcg agtcgtgctg
    12061 ctgtgggtcc gccgtcggcc ggtgtccgcg ggtgctgcgg caccggccgg cgactacgcg
    12121 agtgttcgac cgatagtgat catctctttc gtacgacgac gaagtcggcg agcgccgtga
    12181 aggagtcccg tacgcggtcg ggcatgtcga tggcgtccag ggcttcgatg gcgatgatgt
    12241 gctgacggcg tgcttctccg gccgtccagt cgcggccgcc ggcctgctcg atgagggccg
    12301 cgcgggccgc gaactcctcc tcggagaagt tctcgaagtc gctgctcttg gcgtccgcgg
    12361 cgaggatctc gccgagctgc tcggacgcgg ggccgccggc cgcgagtgcg gcgacgaccg
    12421 gcagggactt cttgcgctgg cgcaggtcgc tccaggtctg cttgccggtg gcctccgggt
    12481 cgccccagat gccgagcagg tcgtcgacgg cctggaaggc gaggccgagg tggtagccgt
    12541 acttctccag cgcgtcggcg gtggcgtcgt ccgcgccgcc gagaaccgcg ccgatggagc
    12601 tggaggccgc gagcagcgcg ccggtcttgt tgccctccat ctccaggcac tcctcgacgc
    12661 tgacgcggtc gcggtgctcg taggagatgt cctgtgcctg accgtcgatc agggcccggg
    12721 tggcggtcgt caggcggcgg gtggcgcggc cggcctcgac cgtgccgagc tccagcagca
    12781 cctcgttggc gagggcgaac agggcgtcgc cgaccaggat cgcctgggcg gggccgtgca
    12841 ccttccagac cgtgtcgcgg tgccggcgct gctcgtcgcc gtccatcagg tcgtcgtgca
    12901 gcagcgagaa gttgtggacg agttcgacgg cgacggcgcc ggggatgccc acctcgggcg
    12961 cggcaccggt gacctgggcg gagagcacgg cgagcgcggg gcgcaccgcc ttgccgccgt
    13021 cgccgtcggc cgggttgccg gcggcgtcga tccagccgaa gtggtaggcg gcgacggtgt
    13081 ccatgggaga cgccagccgg tctacggccg cacgcaggac cggagtggcc agggtccggc
    13141 cacgctccag cagcgcggtc acgtccaccg cggcccgtgg gacgggcgtc gaggccgggg
    13201 gcacagtggg cacagtctct cctcttgttg cggtaccggg ggtgcggggg cctgccgcag
    13261 cctcaagggg catcaggccg cctcctcgaa ctcgaagaga tggcgggggc ggggccggcc
    13321 cagggtgctg agggcggcgt cggccgcact cactccactg cggaccgcac tctccatggt
    13381 cgcgggccac ccggtggcgg tccacgctcc ggccaggtac aggccggggg cattggtgcg
    13441 ggcgccgggc cgcagccgcc cgacgccggg gacgggggcg aacgtggccg tgcgctcccg
    13501 ggtcacgaag aagtcccgca cctcggcgcc ccgggtgccc gggatcagcc gctccagctc
    13561 gggcagatag cgctcgcgca ggtcggcgac cggcaggtcg atctcgtcct gtgcggccga
    13621 ctgggacagc gcgaggtact ggcctgcgcc gagaccggag gcgtcggtgc ggtcgaagac
    13681 ccactgcacc ggggtgccga gggccgcgaa gaaggggcgt gcgagcacct tgcggtcgta
    13741 gacgacatgg acgttgagga tcggggcggt gccgatcccc agcagtcgct caggggcgtc
    13801 gagggcgccg gacggcagca ggccgtgggc ctcgcgctgg ggtacggcga ggacgacggc
    13861 gtcggtttcg aggcgctcgc cgggaacctg aacgctccag gtgccgtttt cgttggtaga
    13921 gacggaggtg acgcgtgtac ggacctcggt acggacgccc gcggagtcga gcgccttgcg
    13981 ggccagccgg tcatgcagtt cgcccagcgg gacgcgggcc cagccgatgt cggccgcgcc
    14041 cgggtcggac agcagaccgg tcttgaacac catcgcggcg agccccagcg aggcgtcgcc
    14101 cgcgaccgcg ttgagggtgg cgaccccgac caggtcccac agggcctcga cggcgcgcgc
    14161 cgactggccg tgcgctgcca gccagctgcc gaagtcctgg gtgtccaggg ccggatcggc
    14221 gaggtcgagc cccttcagcg cgagcgcggc ccgcccgacc gcggcgcgct cggcgagcga
    14281 gaggtgcgga taggcggcca ggctgcgccc caggtggagc gggacgggca gcgggtcgcg
    14341 ccgcagccgg ccgagccgtc tgccctcggg cttggcgacg tcgacgacgg gcacgtccag
    14401 gcggtcctgc agcggtgcca gcgccgcgcc ctcgatccgg tcgaggaacc agcggtaggc
    14461 ggtgcagcag cgcaggtaca catgctggcc gttgtcgacg gtcagctcgc cgcgctgaaa
    14521 ggagaaggcg aggccgccca gcctgggcct gccttcgagc agggtgacac gcacgcctgc
    14581 gtcggcgagc gcgagcgccg cggtgatccc ggcgagcccg ccgccgacca cgacggcgcc
    14641 gcggcctgcc gcgccctcgt ctcgcgcggt gccgtgcgcc ggtgcggggc gcgagccgtc
    14701 gctcatcgtg cgtcctcccg tgggtgccga gcgtgcaggt tgaacggtgc acggtcggcc
    14761 gtcgcagtca gggacgccac gccgcagcgc agggttgcct gccgcttgtc tctcggttcg
    14821 ggaaggtcca tcaggcgcgc ctcctgacgg accggggtga gacatggcgg gtcacatgcc
    14881 gggtgtccag cccggacagg ccgcgtacgg cgacgtaggc cttctccctt ccgggcagcg
    14941 agacccggcc gcgcagcacg gcctcagggt cgcgctcgat tcggtccagc agccggcggt
    15001 agataccggc catggcggcg acgcacgcgc cgctgcgccg gtcgagcatg ggcagcagcc
    15061 ggtagccctc ggcgaaaagg gcgcgggcgc gccgcacttc gaagtgcacg aggcccgcga
    15121 agtcggagcc ctcgggtgga gtcggcccgt cgaacccggc cgagcagccg aacttggcca
    15181 ggtcgtcggc gggcagatag gtacggccgc cctcggcgtc ctcgcggacg tctctgagga
    15241 tgttggtcag ctgcagcgcg agcccaaggg tgtcggcgta ctcggaggcg cgctcggcgc
    15301 cgcgcgctcc cggttcggtg ccgaacacgc cgagcgagat ccggccgatg gcaccggcga
    15361 cacaccggca gtagaccttc aggtcgtccc aggtctcgta ggtctcgccg cgcacgtcca
    15421 tctgaacgcc gtcgatcagc tcgtcgaggc cgccgagcgg gatcgggaaa gcatgtgcgg
    15481 catgggcgag ggcgaccgcg accggatcgg tgtcgtcctc ctcgacctcg ccgtcccgga
    15541 cccgcgcgag cagcgccctg gtgtcctcga gccgcttcag cttcaccccg ccggccaggt
    15601 cgccgtcgcc gatgtcgtcc acgcgccggg aaaaggcgta cagcgccgac atggcgcggc
    15661 gcttgggcgt gggcagcagc cggatgccgt aggcgaagtt gcgggcctgc tgcccggtga
    15721 cggtctcgca gtagctgtag gcggcgagta ccggtgcgga cacgtgtgac ggagaatcca
    15781 cggtccggat cacccctctc ctcgcaggat cacgcccgcc tcacgcagca actggacctt
    15841 gccgggtcgg ggcgggccgg gaagtacgtc gtattcggcg gcggcgatcg cccggatcgc
    15901 cgcccttccc cccgccacga accccgcgag cagcagcttc aatctgccgt ggacgctacc
    15961 caccaggggg gcgccttcat tcagcagatc gcgggcgcgt tgtgcttcgt atgcaaccag
    16021 ggcgcgcacc gatgcgcctg cggtttttgc gccaagatcc gtttcctgga cgtgaaagcg
    16081 cttcatatcc tcggccggga ggtagatccg gtcccggccg agatcctcgg cgacgtcctg
    16141 gaggtgttcc acgatctgca gggcggtgca gatcgcgtcg gagaggcgga tccgctcggg
    16201 ggtcgaggtg ccgctgacat cgaggacgag gcggccgacg gggttggcgg agagttcgca
    16261 gtaggcgagg aggtcgtcgt aggtctcgta ccgggtgacg agctggtcct ggcggttggc
    16321 ggcgatcagg ccgaggaagg gttcgggggt gagggagcgg cggcggacgg tgggctgcag
    16381 ccggcgcagc agcggatggc tgggggtgcc gtcgaagaca tggcgcaggt cggcctcgaa
    16441 ggcgtcgagg aggagcagac ggtcctcggc ctcggcggga gacacgccga gcgcccgggc
    16501 gtcggcgccg ccgggggcga ggtcgccgtc accgatgtcg tcgaccagac gggcgaagcc
    16561 gtagacggcc atgaggtcgt cgcgccacgc ccggggcagg aagaaagggg ccacaggaaa
    16621 gttctcgcta gtggctttgt ccagggtggc gcgttccagg tgaggcgccg tctcggtggc
    16681 cgtcatcggg cgctgcccgg ggcggggacg gcacatgctg cgttgagctg gggagtttcc
    16741 gtagccattg ccgtcacatc tcccgttcta cactgccgac ccaatacaca ctatttcgga
    16801 cacgccgccc ggtaatgcgc ggggtcgccc tggcgcaggg tgtcgcgcat tatcgcccca
    16861 cttgccgctt tccggcaccg gtacagctta cgttgtacaa cccggcatgg tccgtcgggg
    16921 tgtcctgcgc atcacaacaa cacaccgatt ggttccaaga ttcctgacac aggccggagt
    16981 tgacggttcc gttacagacg cggggacccg ccggacgact tccggtagag ccttggccga
    17041 aacgggctac ttgcccgtga acttctcgta ctccttcaaa acctcttcgg tcggtccgtc
    17101 catgcgcagc tcgccgcgtt ccagccacag gacacggtca caggtgtcac ggatggactt
    17161 gttgttgtgg ctgaccagaa acaccgtgcc ggcctccttg cgcagttccc ggatgcgttc
    17221 ctcggagcgc ttctggaact tgcggtcacc ggtggcgagc gcctcgtcga tcatgaggac
    17281 gtcgtggtcc ttggctgcgg cgatggagaa ccgcagccgg gccgccatgc cggaggaata
    17341 cgtccgcatc ggcagggtga tgaagtcgcc cttctcgttg atgcccgaga agtcgacgat
    17401 gtcctggtag cgctccttga tctgctcccg ggacataccc atggcgagac cgccgaggat
    17461 cacgttccgc tcgccggtca ggtcgttcat cagggccgcg ttcacgccga gcagcgaggg
    17521 ctggccgtcg gtgtagacct cgcccttctc cgcgggcagc agaccggcga tggcgcgcag
    17581 cagcgtggac ttgccggatc cgttggagcc gatcaggccg atggcctcgc cgcggtaggc
    17641 gacgaaggac accccgcgca cggcgtgcac cctgcgcacc ccgcgctccc cgccgcgctt
    17701 catgatccgg ctgagggcgg cggtcgcgct gcccttgccg gtcttggcgc cgttgacgcg
    17761 gtagacgatg tgcagctcgt ccgcgatgac cgtcgggcgg cgttcctccg gagcttcggt
    17821 ggcctgcccg gcgttccgct cagccacggc cgtacctctc ctccgcctgc cagaagtaca
    17881 cgaaaccgcc ggcgaagacg agcacggccc agaacagtgc gatggcccac acatgcggcg
    17941 gcaggttcgc ggcgccgtag ccgtcgatca gcgcgtagcg catcaggtcc atgtagaccg
    18001 cggccgggtt gacctggagc agccggacgg cgatctcgga gcggccctcc atcatcttgc
    18061 tgatggagaa catgacgccg gaggtgtaca tccaggtgcg caggatgaac ggcatcagct
    18121 gggcgaggtc cggggtcttg gcgcccatgc gggccacgat cagcgcgagc ccggtgttga
    18181 acaggaactg cagcagcagg acgggcacga tcagcagcca ggccgggctc ggatagctgc
    18241 cgaagccgat cgccacgacg aacatcacga tcatcgagaa gagcagctgc tggagctgct
    18301 gcagcgagaa ggagatgggc agcgaggcgc gcgggaagtg cagggcgcgc accaggccca
    18361 ggttgccgga gatcgcgcgg acgcccgaca tgacggagct ctgcgtgaac gtgaagacga
    18421 acacccccgt gaccaggaac gggatgtaca cgtcctgaga caggccgcgg ctcgcatgca
    18481 ggatcacgcc gaagatgaag tagtacacgg ccgcgttgag cagcggggtc gccacctgcc
    18541 acagctggcc gagcttggcc tggctgtact gcgcggtgag cttcgcctgg gagaaggcga
    18601 ggatgaagtg gcgtcgcccc cacagccggc ggacgtactc ggcgagtgag ggacgggcgc
    18661 cgctgacggc gagcccgtac ttggcggcga gctgcgcggc cgtcagtccc tcgtcgggcg
    18721 gcggtatcgc gctcttcgcg acaccgccgt catgggttgt gtgactcacg agtggaaatc
    18781 cggactctct tggtaagaag cttgctctct tcaggtaaga gaagcttctc agatcaccgg
    18841 aggccggccc agccgggtca gccgccacac cgtgcgccag cgcatgggac gtcgcgggcc
    18901 gcacgccgtg gtccagccct cgcggaatcc gccgaaccac gccctcaggg ccggccggga
    18961 cgggcggcgc agcagcgtga gcagcatcca gaccccgaga tacaccggga ccaggggggc
    19021 ggggaggttg cggcgggcca gccagacccg gttgcgggcg accatgcggt ggtagaccgc
    19081 gtgccgcgag ggcgcggtgg tcgggtggtg cagcaccatg tcggaccggt agtcgatcat
    19141 ccagccggcg tcgagggccc gccaggccag gtcggtctcc tcatgggcgt agaagaactc
    19201 gtccggcagg ccgccgacct cggcgaagac ccgggtgcgt acggcgttgg cgccaccgag
    19261 gaaggtggtg acccgtgagg agcgcatcgg gtcggaggcg cgcagccggg gtacgtgccg
    19321 acgctgggtc tcgccggtgt cggggtcggc gatgcggaag ctgacgatgc ccagctcggg
    19381 gtccgcggcg aaggcctcgc ggcacagctc ggcggtgtcg tggcgggcga gcaggccgtc
    19441 gtcgtcgagg aagagcagta tgtcgacctg gcggccactg ggcccgaagg cctctatgcc
    19501 gacgttgcgg ccgccgggga tgcccaggtt ctcgggcagc tccaccgtcc gtacaccgtc
    19561 ggggacgtcc gggacgggcg agccgttgcc gacgacgacc acctcgaccg ggtcgccgtc
    19621 ctgcttggcg accgagtcga tgagggcccg cagctcctcg ggccggttgc ccatggtgat
    19681 gatgacggcg ccgaccttca cggcactcac ttcagcctgc tggaggcgag gatggacacc
    19741 aggtgcagca gggtctgcag cagggcgata ccggcgagga cggccgtgcc gagccgggtg
    19801 aagaacagat cgccgcgggc ctggtcgacg atcgcgagga ccaggatcag cagcgaggcc
    19861 tcgatgccga ggatgaggcg gtggaacctg agcgccgcgg cggcccggcg ggccagcgcc
    19921 atgccggagg agcgcggctc ggcggcggcc tcctgcacgg gcggcttgcc ggcctggtgc
    19981 cgggcgacgc cgaccaggtc ggtctcggcc ttgatcagga tggcgccgag ggcggcgagc
    20041 gtgccgagga aggcccacag ccagtcgata cggccgctgc cccacaggtc ggcggcgcgc
    20101 aggccgaggc ccaccaggac ggccgcgtcg gtcagatagg cgccgacgcg gtccaggtag
    20161 accccgttca gcgagtactg cttcttccag cgggcgatct cgccgtcgac gcagtccagc
    20221 agcagataca gctgggtggc gaccacgccg agcacggcgc cccagatccc cggcaccagc
    20281 agtgccgggg ccgcgagcac gccgcagacg gtcatcaggt acgtgagctg gttgggcgtg
    20341 accctggtgg tgaccaggta gcggtcgatg cgcagggaca cctcgcgcat gtagaggcgt
    20401 cccgcccagt gctcaccgct gcgccggtcc ttcacccccg cggggtggac gaccggacgg
    20461 agttcagcta ccgatggcct tgacatagtc ggcgtagatg tccttgatct ggttcgtctt
    20521 gaggtcgagg tgctcgagga tcgtgtagcg gccgggccgg gtctcggggg cgaactccac
    20581 cgcgcggacg aactcgtcca gggtgaagcc gatctcctcc ggcagcaccg ggagcccgtg
    20641 ccggcgcagc acgaaagcgg tgtgcaccgc ctcctcgtgc gccccgcgca gatacatcgc
    20701 gaaggccgcg ccgagcccgc actgttcgcc gtgggcggcc gcccgcttgg ggaacagcag
    20761 gtcgaaggcg tggttgatct cgtggcagga gccggaggac ggccgggagt cgccggagat
    20821 cgacatcgag atgccgctga ggaccagcgc ctcggcgagc acctggagga agccgttgtc
    20881 gccgatgccg ccggggtggc gcagcaccgc ctcgccggcc tggcgggcca tggccgcggc
    20941 gagaccgtcg atcttctcgc cggtgacccg gttggacagc tcccagtccg cgaccgcgtt
    21001 gatgttggag atcgcgtcgc cgatgccggc ccgcacgaac cgggccgggg cctcgcggat
    21061 cacgtccagg tcgatgacga ccgcgatcgg gttcggcacg ccgtaggagc cgcgtccggc
    21121 gtcgttgtcg agcgtggcga ccggcgagca cagaccgtcg tgcgcgaggt tcgtcggtac
    21181 ggcgaccagg ggcaggccga cgcgggccgc ggcgaacttg gcgcagtcga tgatcttgcc
    21241 gccgccgagc ccgaccaccg cgtcgtagtg gccggacttc atctcgccgg ccagccggat
    21301 cgcgtcgtcg agggtgcctc cgccgacctc gtaccaggtg gcgccgggca gcgagggggc
    21361 gatgcgctcg cgcagcttgg cgccggagcc gccgctgacg gcgacggcga gccggccgga
    21421 ctgcgcgatg cgctcgtcgg cgaggacacc ggccaggtcg tcgagggcac ccgggcggat
    21481 gtcgacgacg accggcgagg gaatgagccg ggtcagtagc ggcacgcgat ctcccgtccc
    21541 ttggcgaggt cgtcgtggtt gtcgatctcg acccactgga cgtcgccgat cggcgccacg
    21601 tcgatgcgga agccgcggtt gaccagctcc tggtacccgt gctcgtagaa ctgctgcggg
    21661 tcggtctccc agaccgtctt cagcgcgtcg gccaggtcgg gggcggcgtc gccctcgatc
    21721 agggtgacgc cgatgtactc gccggtggcc tcggcgggat ccatcagctt ggtgatcttc
    21781 gtcatgccct tgtcggcgtc gacgacgacc ttcatctcct cgtccgcgag ggacttcacg
    21841 gtgtcgagcg caagaatgat cttcttacct tcgccacgcg cggcgagcag cgtcttctcg
    21901 acggagaccg ggtggacggt gtctccgttg gcgaggatca caccgtcctt gagggcgtca
    21961 cggccgcacc acagggagta ggcgttgttc cactcctcgg ccttgtcgtt gtcgatgagg
    22021 gtgagcttga ggccgtattt ggcctccagc gcctccttgc gctcgtacac ggcctccttg
    22081 cggtagccga cgatgatcgc gacctcggtc agcccgatct cggcgaagtt gccgagggtc
    22141 aggtcgagca cggtgatcga atcctctatg ccggccggcc ccaccggtac cagtgccttg
    22201 ggcaaactgt cggtgtaggg gcgcagacgc cgtccggcgc cggccgccag cacgaggccg
    22261 atcatgcggg ttctccttcg tcgtgtacgg ctggggcccc tgcggagacc cagaagcgga
    22321 tgctctctac gagcaccacg agggcgacgg ccacggcgag gaccgtgagc gcgaccgtga
    22381 actgcggggc ggtgagcacc gcggccagaa cggtgacgag cagcgtccgc ccttcgtgcc
    22441 ccccgatggc gcgcaccagc caggccgggg gcgccccggc gtcgccgcgg atgcggtaca
    22501 ccgtgtcgta gtgatggtag gcgacggcgg ccaccagccc gaaagccgca ggaagggcgc
    22561 cgtttacccc cgccttaccc gcgagggcca ggacggtgcc gtactcggcg gcccggaaga
    22621 agggcgggac cagccagtcg agggcgccct tgagggggcg ggcgacggcg agggccgagg
    22681 tcaggacgta gaccagggcg ccgatcaccg gcagcaccga gccgtggtcc gtgaaggcgg
    22741 agcaggcgac gaccgcggcg ccgcccgcga aggcgacagc gggtacggcg aggcccggca
    22801 ggccccgctt gagcacgcgc cgtacggcct cggtgagcgg gccggagtcg gcgaggtccg
    22861 cgagcgcctg ggcggcccgg ccggtgcgcc gcgccttgcg ggtcagggac cgcagcacac
    22921 ggcccgccgt ggtgtacgtc gccgcgaggg cgcagccgat gagcaggacg tagaaggtga
    22981 tccggggcgt ggtggccgcg gtcaggatcg cgatcatcgc ccagcgctcg ccgatgggca
    23041 ggactatcat ccgccgcagc catatcgtcc agccgacgct gtccagcttg tcggagaggg
    23101 cagcggtcgg gctggtgttg gcggtggcgt cgtggttggc ctcgttgaag gcgaagtcca
    23161 ccgtgtgccg gcaggtctgc aggaccatcg caccgagggc gagggcccac acgtcatcgc
    23221 cgccgtgggc cgcaccgagg gcgaggccgg cgtagtaggc gtactccttg gcccggtcga
    23281 aggtggcatc cagccaggcg ccgagtgtgg agtacttcag cgcgtagcgg gcgagctggc
    23341 cgtcggtgca gtccaggacg aacgaggcga tgagcaggac gccggccgcg atgaaccccg
    23401 cgcgcgtgcc cgtcgccgcg cagcccgccg cgatcagggc ggtgagcagc gaggccgtgg
    23461 tgacctggtt cggggtcagg ccgcggcggg cgcaccagcg ggccaggtag cgcgagtacg
    23521 ggctgatgaa gaacgtggtg aagaagccgt cgcgggactt cacggccgac ttcaggcgta
    23581 cggcctcgtc gtcgacggcg gcgacggcct ggcgggcctc gttgcgggcc tgcgggtcgg
    23641 cggggacggc ggcgaccagg ctgcccagct ccggccggtg caccgcgcag ccgtcggcgt
    23701 cgagggcggt gacgatgcgg tcggcgaggc tgtccacggc gagcgccgta ccgccgccgg
    23761 ccgaggtctc gcgggccacc gcccgggtca gctcctgccg ggcggcccgc tgggcggtga
    23821 cggcgccggg gacggcggag agcgggaagc gcgggtcggt caggccgagg cgcagcgcgt
    23881 gcgggtggcc gacgaagcgg gcgtcgacca gggccacgcg ctcgccggcc ggagcggcgg
    23941 cgagcagggt ctcggcctcg gcggcgtccg ctgccacccg gacgtcgaag ccgagcgccc
    24001 gcagatcgtt ctcgagggac gatccgggca ccggctgacc cgtgacgatg gcggtcgaca
    24061 accgaactca ctccctgggt gccgacgcgc gggcgccggt ctctcacatg atggggcgcc
    24121 ctgtccgcgg cacccgggcg gcatgtcggc agaggctatc cgatgggcgg gagtccctgt
    24181 tcaccggccg ttcacggccg ggcccacggg tgctgcccgg tcctttgccg cgatcatcat
    24241 cggggatccg gggcccaccc cacaaaccgt cggcgcagaa ccgggcaacc gggacagggg
    24301 gacggggcgc tcagggcctg cccggcaatt cccgtcgtcc gcccggtggg cgggcccgtg
    24361 cggcccctcc aggggagtgc gtgccaggcg tcgcggggct ggagcacctc ccacgcacat
    24421 gaagcagtgg ggagggcagt gccggacagg cctttagatc tgacgctgaa catcgggcgg
    24481 ggcgagggtg tctcggtgcg cgagctgatc acggtcatcg gggaggtcac cggggaccac
    24541 cgggagccgc tggtggaggg acgccggccg ggggacgcgc cgcgttcggt cgcctcggcc
    24601 gagcgggccg ggaaggaact gggccggcgg gccgggcgcg gggtgcgcga gatggtggag
    24661 tcggcctggc gggggtggca gcggcaccac ggccgctgag ccgggcaagc gcaccacggc
    24721 accgggccgg gcgcggccct gccccacccg ccctgacctg cggaacgttt ccgcaggtca
    24781 gggcacatga caacggtgtt cagtaccgcg ttgccccata ccccccaccc gtagttcact
    24841 gggccctgcc ggacggaaca gggaagggcg gttgtcatgg gggcagggca cgaccacggg
    24901 catgcgcaca gccatgcgcc ggccacgggt acggctgcgg cggcctaccg gggccggctg
    24961 cggatcgcgc tgggcatcac gctcacgatc atgctggtgg agatcgtcgg cggcctgctc
    25021 gcggattcgc tcgcgctgat cgcggacgcg gcgcacatgg cgaccgacgc ggtgggcctc
    25081 ggcatggccc tgctcgcgat ccacttcgcg aaccgcccgc cgagcaccaa ccgcaccttc
    25141 ggctacgccc gcgccgagat cctcgccgcc ctggccaact gcgtgctgct gctcggggtc
    25201 ggcggatacg tcctgtacga ggcggtcgag cggtttgtga cgcccgcgga cacccgcggc
    25261 ggcctgatgg tcgttttcgg tctgatcggc ctggtcgcga actcggtctc actgaccctg
    25321 ctgatgcgcg ggcagaagga gagcctgaac gtgcgcggcg ccttcctgga ggtcgccgcg
    25381 gacgcgctgg gctcgggggc ggtgctggtc tcgggagcgg tgatcctcac caccggatgg
    25441 cagaccgccg acccggtcgc ctcgatcgcc atcggcctga tgatcgtgcc gaggacgctg
    25501 aagctgctgc gcgagacgct ggacgtgctg ctggagtcgg ctccgaagaa cgtcgacatg
    25561 gccgaggtgc gggcgcacat cctggcgctg gacggcgtgg aggacgtgca cgacctgcat
    25621 gcctggacga tcacttcggg catgccggtg ctgtcggcgc acgtggtggt cagctcggac
    25681 acgctgagcg ccatcgggca cgagaagctg ctgcatgagc tgcagggctg cctcggcgat
    25741 cacttcgatg tggagcactg caccttccag ctggagccgg gcgggcacgc ggagcacgag
    25801 gctcgcctgt gccactgacg gtccgctcgg gcgttcgacg cccctgggcg attccgtgct
    25861 tctccgaccg ggcacgatga tctaccgggt ccggcttcgg caccgcgccg cgcgtcggca
    25921 tggcggaaag tgccgggagt gccggattcg tacggcagac ttggagtgcg aagaccgagg
    25981 cgaaggatgg gtatgccgat cacacctgcc accgcgaagc acagctcgtc gaatggcacc
    26041 gaagaggcga ttctgctgga actggtcgac gagaagggtg tcacgatcgg tacggcggag
    26101 aagctcgccg cccaccagcc gcccggacag ctgcatcgcg cgttctcggt gttcctcttc
    26161 gacgaacagg gacggctgct gctccagcag cgggcgctcg gcaagtacca ctcccccggt
    26221 gtctggtcca acacctgctg cggccacccc ttccccggtg aggcgccgtt cgccgccgcg
    26281 gcccggcgca cgttcgagga gctgggcgtg tccccgtcgc tgctcgcgga ggcgggccgg
    26341 gtccgctaca accaccccga cccggcctcg ggcctcgtcg agcaggagta caaccacctg
    26401 ttcgtcggcc tggtgcaggc gccgctcgcc ccggacccgg aggaggtcgg cgggaccgcc
    26461 ttcgtgacgg cggccgagct gacggagcgc cacgagcgcg acccgttctc ggcgtggttc
    26521 atgaccgtcc tggacgcggc ccgcccggcg atcagggaac tgacgggcct gtccgcgggc
    26581 tggtgagagg cactccggca gcgtcacggg ggctacggct ccacgannnn nnnnnnnnnn
    26641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnn
//
