LOCUS       NZ_CM002285            21047 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Streptomyces roseochromogenus subsp. oscitans DS 12.976 chromosome,
            whole genome shotgun sequence.
ACCESSION   NZ_CM002285
VERSION     NZ_CM002285.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Kalinowski,J., Heide,L. and Apel,A.K.
  TITLE     Draft Genome Sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976, Producer of the Aminocoumarin Antibiotic
            Clorobiocin
  JOURNAL   Genome Announc 2 (1), e01147-13 (2014)
   PUBMED   24407645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Draft genome sequence of Streptomyces roseochromogenes subsp.
            oscitans DS 12.976
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 9663240)
  AUTHORS   Ruckert,C., Szczepanowski,R., Heide,L., Kalinowski,J. and Apel,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-SEP-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.5.3
            Assembly Name                     :: S.roseochromogenes_v1
            Genome Coverage                   :: 20.4x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000497445.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 03:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,098
            CDSs (total)                      :: 9,013
            Genes (coding)                    :: 8,393
            CDSs (with protein)               :: 8,393
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6 (16S, 23S)
            complete rRNAs                    :: 6, 6 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 227 of 620
            Pseudo Genes (incomplete)         :: 534 of 620
            Pseudo Genes (internal stop)      :: 54 of 620
            Pseudo Genes (multiple problems)  :: 178 of 620
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:03:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 639933
            Orig. end                         :: 660980
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002285.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21047
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="atropopeptide"
                     /region_number="5"
                     /rules="atropopeptide_p450"
                     /tool="antismash"
     cand_cluster    1..21047
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="atropopeptide_p450"
                     /kind="single"
                     /product="atropopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21047
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11047](-)"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11047)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
     gene            complement(117..446)
                     /locus_tag="M878_RS53160"
                     /old_locus_tag="M878_03000"
     CDS             complement(117..446)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540956.1"
                     /locus_tag="M878_RS53160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03000"
                     /product="AzlD domain-containing protein"
                     /protein_id="WP_023544624.1"
                     /transl_table=11
                     /translation="MPDATYLVAAVLVSGAVTWALRALPFTALGPLRASRTVQYLQPRM
                     PAGIMVILVAYCLRGLPLTHTAVLAPLAALAVTVGVHLWRRNAPLSILAGTAVHVALVS
                     TVFTY"
     gene            complement(439..1083)
                     /locus_tag="M878_RS53165"
                     /old_locus_tag="M878_03005"
     CDS             complement(439..1083)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573496.1"
                     /locus_tag="M878_RS53165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03005"
                     /product="AzlC family ABC transporter permease"
                     /protein_id="WP_245238361.1"
                     /transl_table=11
                     /translation="MGLAFVPLGIAFGVLVAHAGVAWWWATLSSALIYGGSFEFLLIGM
                     VTAAVPLASVAVSAFLVNVRHVFYALSFPLHRVKGPLGRAYSTFALCDEAYALTAGEQA
                     RSWSGRRIRRLQLFLHLYWVGGATAGALLGSLVPAGVTGLDFALTALFTVLALDAVRDR
                     PGDLPTPLLALLSALTARLLFPGSLLIAAFALFTAGLLARHLTTRGRVRHA"
     misc_feature    1099..1108
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(1197..1211)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.52"
                     /tool="antismash"
     misc_feature    1198..1211
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.62"
                     /tool="antismash"
     gene            1266..1712
                     /locus_tag="M878_RS53170"
                     /old_locus_tag="M878_03010"
     CDS             1266..1712
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019433036.1"
                     /locus_tag="M878_RS53170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03010"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_023544626.1"
                     /transl_table=11
                     /translation="MNLDAIDRDILFHLCRDGRLTNVELAQRVGLTPPPCLRRVKRLEE
                     AGVITGYRAVVDPVALGRGLEVLIDVEVSANDRTTFLEFEDIVAGYDEVIEFRRMYGRP
                     DYFLRVAVADHAAYEAFLVDKLSGLPCVLRIDSHLTMKTIKTGP"
     misc_feature    1289..1303
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.68"
                     /tool="antismash"
     gene            1803..2591
                     /locus_tag="M878_RS53175"
                     /old_locus_tag="M878_03015"
     CDS             1803..2591
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004981013.1"
                     /locus_tag="M878_RS53175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03015"
                     /product="thioesterase family protein"
                     /protein_id="WP_023544627.1"
                     /transl_table=11
                     /translation="MTASYFERIDRHRFKPTPHASGAWDTDEQHFSPLAGLVVHAIDQY
                     RAERPPTGLLLSRISYDILGRLALDECEIQVESIRPGRTIELLEAVVRIADRPVVRARA
                     WLLTEVDTSAVAGGAEERLTPPEGLAGQSLGSVWPGGHCASVDVRPVGPAQPGRATAWI
                     STDLDLVAGEPSSPLASYVALIDTANGIAVRRPPTEWMFPNVDLTIHLHRQPAGRWVGL
                     DTTVVFGPTGLGLTSSILHDVHGPVGQAQQALTVRPLPGR"
     gene            complement(2664..3533)
                     /locus_tag="M878_RS53180"
                     /old_locus_tag="M878_03020"
     CDS             complement(2664..3533)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093179.1"
                     /locus_tag="M878_RS53180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03020"
                     /product="EamA family transporter"
                     /protein_id="WP_023544628.1"
                     /transl_table=11
                     /translation="MPAPGLVLGGILGLQGGAALTTRLYPAVGPAGVVTLRLAIAALAL
                     TALWRPRLRGDRVTLGIAAAAGTLLAVHHLAYYEAVSRLPLGAATTLEFLGPFAIALCG
                     SRRAPDLLWAALAATGVLLLSHSGTALDATGIACATLAGCCWGGYILVGKRLAERVPDG
                     RGLALAVTWAALLSLPYGITQAGTRLLDPDTLAVATAVALLSSVLPYTFQLEALRRLTP
                     RVFGILTSLEPAIGALIGLLLLSQHLAAPQWAGVAAVALASVGATRTEGRADEVRAADD
                     RAEAARDG"
     gene            3706..4314
                     /locus_tag="M878_RS53185"
                     /old_locus_tag="M878_03025"
     CDS             3706..4314
                     /EC_number="1.5.1.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360879.1"
                     /locus_tag="M878_RS53185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03025"
                     /product="flavin reductase family protein"
                     /protein_id="WP_023544629.1"
                     /transl_table=11
                     /translation="MRVDYSPDSMPTGAFYRLLTAVVVPRPIAWISTLAPDGETANLAP
                     HSFFTVACTAPPVVQFTSVGRKDSLRNVEETGEFVVNFAPEPLFAEINATATDFPRDQG
                     EFEVVGIEREPSSRVRPPRVAASPVALECTLHSTLRLGDSTVVFGRVVHAAVREDVLMD
                     GRPDIGRLRPLSRLGGNEWGTVGEVRELARVPYRDRTRD"
     gene            4643..5323
                     /locus_tag="M878_RS53190"
                     /old_locus_tag="M878_03030"
     CDS             4643..5323
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117284.1"
                     /locus_tag="M878_RS53190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03030"
                     /product="maleylpyruvate isomerase N-terminal
                     domain-containing protein"
                     /protein_id="WP_023544630.1"
                     /transl_table=11
                     /translation="MSSRGAAGPARALRAAYEAASAAVAGLGDEESWLPTGCTGWAVRD
                     LVFHCLGDAQRALVALHTPAREPVDRDAVTYWQDWRPDTTGAANGRRWVRVNASMFLDF
                     GQLRGLYLETLAAAVHAAEATDPAQHVGTQGHVLTAGDLLTTLAVEATVHHLDLTVRLP
                     HPPGPAPEGLTAVRATLDGLLGRPALPEWSDAHYARVGTGRATLTEAERTALGAAADRF
                     PLFG"
     misc_feature    complement(5426..5441)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.97"
                     /tool="antismash"
     misc_feature    5427..5440
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    complement(5442..5457)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.79"
                     /tool="antismash"
     gene            5541..7289
                     /locus_tag="M878_RS53195"
                     /old_locus_tag="M878_03035"
     CDS             5541..7289
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014141077.1"
                     /locus_tag="M878_RS53195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03035"
                     /product="carbohydrate binding domain-containing protein"
                     /protein_id="WP_023544631.1"
                     /transl_table=11
                     /translation="MTRPRPVRALLAGLATLAASTGLALGAGGTAHAATSLPTHVFAPY
                     FEAYNGDSPAALSQASGAKYLTMAFLQADKKGSCTPYWNGDTSKPVSSSVFGADFTTIR
                     SRGGDVIPSLGGYGADNAGTEIADSCTNVDSIAAAYEKIITTYDVSRLDMDVEDNSLTD
                     TAGIDRRNQAIKKVQDWAAANGRSVQFSYTLPTTTTGLADSGLAVLRSAKSAGAKVDVV
                     NIMTFDYYDGATHHMATDTETAASGLHDQLAALYPNLSDSQLWNMVGVTEMPGVDDYGP
                     AETFTTADATTVYDWAVSKGINTLSFWALQRDNGGCPGGSASDTCSGIAQDTWYFTHTF
                     APFTGGTTTPPANDFSVSLSPATASVDPGATATATVRTSVTSGAAQSVDLAVSGAPSGV
                     TASLSPSSVTAGGTSTLTVKTAAATTPGTYTLTVTGTAGSTRHSSTLTLTVNGSGGTAT
                     LANGDFETGSLAPWTCDTGASVVSSPAHGGSHALKTAPSDSQPGQCAQTLTLKPNASYT
                     LSGWVQGPYAYLGVSGGATASTWTSSSSWSKLTVPFTTGSSGTVTVYVHGWYGQGAVYA
                     DDLSVS"
     gene            7469..>7926
                     /locus_tag="M878_RS53200"
                     /old_locus_tag="M878_03040"
                     /pseudo=""
     CDS             7469..>7926
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018851426.1"
                     /locus_tag="M878_RS53200"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03040"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIELAAAFAVAGAASNAVGTAFQRKAASASSRGGLRLLAELVRRP
                     LWAIGMCGVVCAALFQSLALVNGPLALVQPLFILELPFALLVAAPLMHRRLPRSGWWGV
                     GGCVLGLAVLLIAAAPHGAVHHAPLTRWIPALCLCLGGMAAAVLLAGR"
     assembly_gap    7927..8685
                     /estimated_length=759
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     gene            <8686..9062
                     /locus_tag="M878_RS53205"
                     /old_locus_tag="M878_03045"
                     /pseudo=""
     CDS             <8690..9062
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430470.1"
                     /locus_tag="M878_RS53205"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03045"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="ALTAALLKSASGTFADHGFTAFLRSWQTYGFALTGIAAVVLLENA
                     LQAGPLAAAQPALTIGDAVVSLTLGMTLFEERIRTGWWLVPEACSALLIVVGVVVLSRA
                     VQHITVASARAARATEGSSG"
     gene            complement(9167..9316)
                     /locus_tag="M878_RS99385"
     CDS             complement(9167..9316)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M878_RS99385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_245238014.1"
                     /transl_table=11
                     /translation="MEQRPQPGAEVSLVVFQMIDVAADPVDGGVLDGGQLRVERRGRPR
                     QGRG"
     gene            9704..9934
                     /locus_tag="M878_RS99390"
                     /old_locus_tag="M878_03055"
     CDS             9704..9934
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013209.4"
                     /locus_tag="M878_RS99390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03055"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_023544635.1"
                     /transl_table=11
                     /translation="MAAVLGRSRTRLLIELDTPASTTQLAHRTGLSPAGVSQYLTTLRG
                     AGLVGAHRACRSVLYARTAAAETLLEAAFTT"
     gene            complement(10001..11047)
                     /locus_tag="M878_RS53215"
                     /old_locus_tag="M878_03060"
     CDS             complement(10001..11047)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_p450"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000172: Biaryl bond formation (75% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568017.1"
                     /locus_tag="M878_RS53215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03060"
                     /product="cytochrome P450"
                     /protein_id="WP_023544636.1"
                     /sec_met_domain="atropopeptide_p450 (E-value: 4.3e-188,
                     bitscore: 623.6, seeds: 287, tool: rule-based-clusters)"
                     /sec_met_domain="p450 (E-value: 8.6e-14, bitscore: 50.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPSSATRARTTVFAPRLAALIGAHTGQDVFRLEPDTVGVAGHEV
                     ADRILAARRATETERPTFKPLHGRSITRTEASTVTRTLGNDVREALSGPLPEDADLAGS
                     WPLTGHLFLRDLILGQDPYRLRMLMSRNLELTPKLTWSVIAIGAALPGWPRPSSRLTGL
                     AGRAARATGYQERRYAMGMYRRAAAPVCFTVSTLVANALWLGAPFDDATPNRGIILESL
                     RLLPPSWNILRNASPEYPAVDDRIGERDDVLVLPLLSHRDPALWDDPDTFRPERWDDLD
                     PETTPGYLPFGHSSERCWGRHMVMPLAELLLDLVRGSGLVVDPRQRTGKVPLLGLLGVA
                     DVRLTHPR"
     misc_feature    complement(11384..11404)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.02"
                     /tool="antismash"
     gene            complement(11575..12108)
                     /locus_tag="M878_RS53220"
                     /old_locus_tag="M878_03070"
     CDS             complement(11575..12108)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986205.1"
                     /locus_tag="M878_RS53220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03070"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_023544637.1"
                     /transl_table=11
                     /translation="MKAAVRVFHEQGVEKTTLGDIARAAEVPLGNVYYYFKTKDQLVDA
                     TVDAHREQLEALTAQLDALPDPAARLKALVAGWVDQRETAARYGCPFGTLATELDKRDD
                     GLDQAAAQVMRALLAWVEAQFTQLGRADAAALAVELVAAYQGMSVLTNTLRDPGLMAVQ
                     GERLQSWIDGIAGR"
     misc_feature    complement(12097..12106)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            12297..13118
                     /locus_tag="M878_RS53225"
                     /old_locus_tag="M878_03075"
     CDS             12297..13118
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179776.1"
                     /locus_tag="M878_RS53225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03075"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_023544638.1"
                     /transl_table=11
                     /translation="MIVVTGATGNVGRALVAELSEGGDTVTALARHIGTEDVPPGVRAV
                     AADLGQPQSLAPALSGAKALFLLVAGEDPAGILRQAAAAGVAKVVLLSSLGAGTRPETY
                     THATRFEAAMAPSGLPFTVLRSGGLASNALAWAEPIRRYRTAAAPFADVALPFVDPDDV
                     AAVAAAVLRGDGHDGALYTLTGPEPTTPRQRAAAIAAVLGEPVTFVEQSREEAHAQMIR
                     FMPAAVAEGTLAVLGAPTPEEQAVGTDVERLLGRPAAPFSAWAARHVAAFR"
     gene            13312..14553
                     /locus_tag="M878_RS53230"
                     /old_locus_tag="M878_03080"
     CDS             13312..14553
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415768.1"
                     /locus_tag="M878_RS53230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03080"
                     /product="hypothetical protein"
                     /protein_id="WP_031223864.1"
                     /transl_table=11
                     /translation="MGGISRRNVARLGLGAGIGAAAALAAFGGQDGPSGSPGGPKGQGA
                     APRQGALRLIGDGSTAYTGRQPHQPEPPAPLEPGETPPQFVVFSWDGAGELGTGLFPRF
                     LELGRTHGAHMTFFLSGLYLLPEGKKRLYDPPNNPVGASDIGYLTDAHLKETLKYVRQA
                     WLDGHEIGTHFNGHFCEGPGSVANWTPEQWRSEIEQARAFVTSWRTHTGWHDHPPLPFD
                     YDKELVGGRTPCLLGQANLLPVARELGWRYDASSPGGLQRWPRKRHGVWDLPLQSIPFP
                     GHSFEVLSMDYNMLANQSKNSTRAPSYNYPYWRAQATQAYVAGFQRAYETNRAPLFIGN
                     HFEQWNGGIYMDAAEEALGQIAGREDVRLVSFRQFVDWLDTQDPAILRQLRTLQVGEKP
                     SAGWAAFLHPAQRT"
     gene            14865..16274
                     /locus_tag="M878_RS53235"
                     /old_locus_tag="M878_03085"
     CDS             14865..16274
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115712.1"
                     /locus_tag="M878_RS53235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03085"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_031223865.1"
                     /transl_table=11
                     /translation="MHSARLSRAALFTVLLLTVETACTSSGGRPDEAPRPGAVSAGDAL
                     FPALGNSGYDVAHYALTLDYVPETNELAGTAVITARAEQPLSRFSLDLAGLSVRDASID
                     GADAGVSSKKNKLILTPAHPLKTGATFTTTIHYSGTPKMFTAADASVEGWIETDDGAAA
                     LGEPTGSMAWFPGNHHPSDKALYDITITVPKGYTAVSNGELTGIRDKGRRTTSRWHMGE
                     PMASYVATVVVGSFDISTTTTAQGLPVYIAIDPDEVEDSPDMAELIPQIIDWAGSRFGR
                     YPFASTGAIVDHLPDLEYALETQTKPYFEKAPDETLVVHELAHQWFGNSVTPRSWQDMW
                     LSEGFATYAEWIWQEDQGDTTADEIFNAFYDGTHPESEGIWDFPPAQPPSAKQVSDSPV
                     YGRGAMTLHRLRETVGDNSFFTILKTWTEQHRYGNAHTTQFIKLCEKESGMDLTELFDT
                     WLYGEEKPTLA"
     gene            16563..18236
                     /locus_tag="M878_RS53240"
                     /old_locus_tag="M878_03090"
     CDS             16563..18236
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069613.1"
                     /locus_tag="M878_RS53240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03090"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_023544641.1"
                     /transl_table=11
                     /translation="MIRRSARPARPARTVVAAAAALAATSALTATAIEPASAHTPGHPA
                     ARHVLLLSVDGLHQSDLAWYIARHPHSALARLAGGGVEYTHARSTIPSDSFPGMVGQLT
                     GGNPGTTGVYYDDGYDAALLPAGTTKCAGAERGAEVDLTEDLDKNKDSIDAGQGLTGLP
                     GSILKMTGHAASLIDPTKLPVDPKSCAPVSPHAYLRVNTVFDVARKAGLRTAWSDKHVA
                     YDILNGPSGNGIQDLFAPEINSTAIGYPAGDDWTKDNAATEQYDGYKVQAVLNEIDGYD
                     HSGTHKVGTPAVFGMNFQSVSTAQKLPASDGLAGGYKAKGVPGPLLEKNLAFVDREVGA
                     FVAELGKRHLDGSTTVVLSAKHGQSPTDPKALTRIDDGPLLDGLNAAWKKAHPGSGDLV
                     AHAVDDDAMLIWLTDRSQAATDFAKAYLLAQSGTGNGIDGNAKLFTASGLNALYAGADA
                     ARYFHVKPGDSRVPDLFGITQYGVVYTGGKKKIAEHGGAHADDLDVPLVVSGAVIPHDV
                     RVAAPVETTQIAPTILRLLGLDPRALDAVRAEHTPALPVR"
     gene            complement(18319..18951)
                     /locus_tag="M878_RS53245"
                     /old_locus_tag="M878_03095"
     CDS             complement(18319..18951)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484059.1"
                     /locus_tag="M878_RS53245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03095"
                     /product="LysE family transporter"
                     /protein_id="WP_023544642.1"
                     /transl_table=11
                     /translation="MTGALAAGLLAGYGIAVPVGAVATYLVALTARTSWKVGACAALGV
                     ATADGLYALIAAFGGAALVPTIKPIMLPLRYASACVLLVLAVRSAATAIRHYREHKPTT
                     RTDEIPLSPARAYAGLLGITMTNPMTVIYFAALVLGSRGTAVQDHFQQAAFVLAAFVAS
                     ASWQLLLASGGALLGRTVTGTRGRLLTALVSSTLITALAAHLLITAL"
     gene            19177..19779
                     /locus_tag="M878_RS46815"
     CDS             19177..19779
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049289.1"
                     /locus_tag="M878_RS46815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YdcF family protein"
                     /protein_id="WP_031223871.1"
                     /transl_table=11
                     /translation="MRRGTALAVAGAAALAWGEWLNWRWSRALLGSGGGASEAVVVLGY
                     RNPQATANLINRWRVRAGIRSITGDSARDTRVIFSGGATTSGGAAEARLMADYAKSVLE
                     FDGTVVLEDQSRTTWENVMKVTPLLEDADRIKIVSQPAHALKARAYLRRQRPDLAVKLV
                     RADDYRPGEWMIVKPLLALYGLWTLRGLKAGERKISL"
     gene            complement(19971..20864)
                     /locus_tag="M878_RS53250"
                     /old_locus_tag="M878_03105"
     CDS             complement(19971..20864)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (37-282). E-value:
                     2.1e-34. Score: 111.1. Matches aSDomain:
                     nrpspksdomains_M878_RS53250_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="M878_RS53250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M878_03105"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_023544644.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-22, bitscore: 80.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.7e-24, bitscore:
                     86.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METVDHIPPLPELDGVRHRYVSVRGLRLHIAEAGQGEPVVLLHGF
                     PQHWYGWRQLIPLLSGRYRLLCVDQRGFGWSDAPHQGYDTDSRVADVLGLLDELGLDRV
                     HLIGHDWGAWTGFHVCLTAPERIRHHLALNMMHPWPLHRRLMPESWRFWYTAVLEQPLL
                     GRWMLRNRPGFTRYLMRKGVVEQAVWTPGAMGEFVRSSQEPGRARAGEALHRAFALRDI
                     AKLVLGRYKRLRLTTPTVILAGERDFMLPPSVITDAGRHADDLRVQVVPGCGHYLHEER
                     PGLVAETAVTLFSGRH"
     aSDomain        complement(20019..20753)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M878_RS53250_Abhydrolase_1.1"
                     /evalue="2.10E-34"
                     /label="M878_RS53250_Abhydrolase_1.1"
                     /locus_tag="M878_RS53250"
                     /protein_end="282"
                     /protein_start="37"
                     /score="111.1"
                     /tool="antismash"
                     /translation="PVVLLHGFPQHWYGWRQLIPLLSGRYRLLCVDQRGFGWSDAPHQG
                     YDTDSRVADVLGLLDELGLDRVHLIGHDWGAWTGFHVCLTAPERIRHHLALNMMHPWPL
                     HRRLMPESWRFWYTAVLEQPLLGRWMLRNRPGFTRYLMRKGVVEQAVWTPGAMGEFVRS
                     SQEPGRARAGEALHRAFALRDIAKLVLGRYKRLRLTTPTVILAGERDFMLPPSVITDAG
                     RHADDLRVQVVPGCGHYLHEERP"
ORIGIN
        1 tgcgggaggc cgccgtgaag gccaagcagc tcgccgagcg cctcgcggcc tgaccgtacc
       61 gccccaacgc ggcccgggcg ccgccgactt gtgctcggcg cccggacctc gtcacgtcaa
      121 tacgtgaaga ccgtactgac cagcgcgaca tggacggcgg taccggccag aatgctcagc
      181 ggggcgttac gacgccacag gtgcacgccg acggtgacgg ccagggccgc cagcggggcc
      241 agcacggcgg tgtgggtgag cggaaggccg cgcaggcagt acgcgacgag gatcaccatg
      301 atcccggcgg gcatccgggg ctggaggtac tgcacggtcc ggcttgcccg cagtggcccg
      361 agcgcggtga aagggagggc acgcagcgcc caggtgacgg cgcccgagac gaggaccgcg
      421 gcgacgaggt aggtcgcgtc aggcatggcg cacccttcct cgggtggtca ggtggcgggc
      481 caggagcccg gccgtgaaca gggcgaaggc ggcgatcagc agactgcccg ggaaaagcag
      541 ccgggcggtg agcgcgctca gcagggcgag cagcggcgtg ggcagatcgc ccggccggtc
      601 gcggacggca tcgagcgcca gcacggtgaa cagggccgtg agcgcgaagt ccagaccggt
      661 gactccggcg gggacgagcg agccgagcag cgctcccgcg gtggctccgc cgacccagta
      721 caggtgcagg aagagctgca gccgccggat gcgacgcccg gaccaggagc gggcctgctc
      781 cccggcggtc agcgcgtagg cctcgtcaca cagtgcgaag gtgctgtacg ccctcccgag
      841 cggccccttc acccggtgca gcgggaagga cagcgcgtag aagacgtgcc ggacgttcac
      901 caggaacgcg gagacggcga ccgaggccag cggcacggcg gcggtgacca tgccgatcag
      961 caggaactcg aaggacccgc cgtagatcag cgcgctggac agggtcgccc accaccaggc
     1021 gactcccgcg tgggcgacga gcacgccgaa ggcgatgccg agcgggacga aggccagccc
     1081 cacggaggcg gagtccgcga aggcggccca cgtgtcggac ggcgtccggg acggcggcgc
     1141 ggcggacccg gtcggtgccg ggccgccggc aacggcggga ggtatacaca tagcgacatt
     1201 ttaggaagaa tcgcttggca tatggttgcc aatagtgtcc gtagaatggc acggtgcgca
     1261 atgaaatgaa cctggacgcc atcgaccggg acattctgtt tcatctctgc cgtgacggcc
     1321 ggctgaccaa cgtcgagctg gcccagcggg tgggcctgac cccaccgccg tgtctgcgcc
     1381 gggtcaagcg gctggaggag gccggggtca tcaccggata ccgggcggtg gtggatcccg
     1441 tggcgctcgg ccgggggctg gaagtcctga tcgacgtgga ggtcagcgcc aacgaccgca
     1501 cgaccttcct ggagttcgag gacatcgtgg ccggatacga cgaggtcatc gagttccggc
     1561 gcatgtacgg ccgccccgac tatttcctcc gcgtggccgt cgccgaccat gccgcgtacg
     1621 aggccttcct ggtggacaag ttgagcggtc tgccctgtgt gctgcggatc gactcccatc
     1681 tgacgatgaa gacgatcaag accggcccgt gagcgggcgg ccatcccggt gtacggtgca
     1741 acgacccgca ccaacgctcc ccgtccctgt ccaccgtggt acgccgtgac gagaggcacc
     1801 cgttgaccgc cagctacttc gagcgcatcg accggcatcg cttcaagccc accccgcatg
     1861 cgagcggcgc gtgggacacc gacgagcagc acttcagccc gctcgccgga ctcgtggtcc
     1921 acgcgatcga ccagtaccgc gccgagcgcc cgccgaccgg actgctgctg tccaggatca
     1981 gctacgacat cctgggtcgc ctcgccctgg acgagtgcga gatccaggtg gagtcgatcc
     2041 ggcccggccg caccatcgaa ctgctcgaag cggtcgtacg catcgcggac cggccggtgg
     2101 tccgggcccg tgcctggctg ctcaccgagg tggacaccag cgccgtggcc ggcggcgccg
     2161 aggaacgtct cacccctccg gagggactcg ccggtcagtc gctgggctcg gtctggccag
     2221 gcggccactg cgcgtccgtc gacgtccggc cggtcggacc cgcccagccg gggcgcgcca
     2281 cggcctggat ctccacggac ctcgacctcg tcgccggcga gccgagcagc ccgctcgcct
     2341 cctatgtcgc cctgatcgac acggccaacg gcatcgccgt acgccggccg ccgaccgagt
     2401 ggatgttccc caacgtcgac ctgacgatcc atctgcaccg gcaaccggcg ggccgctggg
     2461 tcggcctgga caccaccgtc gtcttcggcc ccaccggcct cggcctcacg agcagcattc
     2521 tgcacgacgt ccacggcccg gtcggccagg cccaacaggc cctcacggta cgcccgttgc
     2581 ccggcaggtg accccggccg gcggcatcag cgacgaccgc cgagcgcatc cggccaccgc
     2641 gggaggcgcg gtgcgggcgt gccctagccg tcccgggcag cctcggcccg gtcgtccgcg
     2701 gctcgcacct cgtctgccct gccctccgtg cgcgtcgctc ccaccgacgc cagggccact
     2761 gccgccaccc ccgcccactg gggcgcggcg aggtgctggc tcaggaggag caggccgatc
     2821 agggcgccga tcgccggttc cagactggtg aggatgccga atacgcgggg cgtgagccgg
     2881 cgcagcgctt ccagttggaa ggtgtacggc aggacgctgg agagcagggc gaccgccgtg
     2941 gccacggcga gggtgtccgg gtccagaagg cgggtgcccg cctgtgtgat gccgtaggga
     3001 aggctgagca gtgcggccca ggtgacggcg agggcgaggc cgcggccgtc ggggacgcgt
     3061 tcggcgagcc gtttgccgac caggatgtag cctccccagc aacaaccggc gagggtcgcg
     3121 catgcgatgc ccgtggcgtc gagggccgta ccggagtggc tgagcaggag gactccggtc
     3181 gcggccaggg ccgcccagag caggtcgggg gcgcggcgcg agccgcacag ggcgatggcg
     3241 aagggaccga ggaactccag ggtggtggcg gcgcccaacg gcagccggga gaccgcctcg
     3301 tagtacgcga ggtggtgcac ggcgagcagg gtgccggcgg cggccgcgat gccgagggtg
     3361 acccggtcgc cgcggagccg gggccgccac agcgcggtga gggcgagcgc ggcgatggcc
     3421 agccgcaggg tcaccacgcc cgccggaccc acggcggggt agagacgggt cgtcagcgcg
     3481 gccccgccct gcaggccgag gatcccgccg aggacgagcc ccggggccgg cacggcgccg
     3541 agtccccggc tcagggcgag ggtcgcgcgt gcgcgaggag tcaggtgctg actgatggtt
     3601 atcgggctcc ttgtgcgact gccccgcagc ctaggcggcg gccccatgat gatcaacggt
     3661 gggggcgggg ggcacggtgg tcggggtacg gcttagcgtg ctgtcatgcg cgtcgactac
     3721 tcccccgatt ccatgccgac cggtgccttc taccgtctgc tcacggccgt cgtcgtaccc
     3781 cggccgatcg cctggatctc gactctcgcg ccggacggtg aaacggcgaa cctggccccg
     3841 cactcgttct tcaccgtggc ctgcaccgct ccccccgtcg tccagttcac gtcggtgggc
     3901 cggaaggact cgctgcgcaa tgtcgaggag accggcgagt tcgtcgtcaa cttcgccccg
     3961 gagccgctct tcgccgagat caacgcgacc gcgaccgact tcccgcgcga ccagggcgag
     4021 ttcgaggtgg tgggcatcga gcgggagccg tcgtcgcggg tgcggccgcc gcgggtggcg
     4081 gcgtctccgg tcgccctgga gtgcacgctg cactcgacgc tgcgcctcgg tgactcgacg
     4141 gtggtgttcg gccgggtcgt gcacgccgcc gtccgcgagg acgtgctgat ggacggccgg
     4201 cccgacatcg gccgactgcg gccgctgtcc cggctgggcg ggaacgagtg gggcacggtg
     4261 ggcgaggtcc gcgagctggc ccgggtgccg taccgggacc ggacccgcga ctgagccgcc
     4321 cggcctctcc cgctcccgcc gctgagcccc acaagcccag gccggcaccg gcacgagggg
     4381 cgcgccccgg cacggcaccg ggcgcacgcc gtcgtgcacg ccgggccggg ccgtgccgag
     4441 cagttcgccg aagtcccggc ttttggcctg ttgccgctga tcccggtcta cgtcgccccg
     4501 cggctgtcgg cggacacggc gacgtctagt cgggtgtgac acgctgtagg gcggacgaaa
     4561 ccgggggcgc gagcacgggg cggcgcatga gtacgggcgg gcgcatgagc acactggggg
     4621 gtgtatgagc acagggggac gcttgagctc aaggggtgcc gcaggcccgg cgcgggcgct
     4681 gcgtgcggcg tacgaggcgg cgtcggcggc cgtcgcgggc ctcggtgacg aggagtcgtg
     4741 gctgccgacc ggctgtaccg ggtgggcggt ccgcgacctc gtcttccact gcctggggga
     4801 cgcccagcgg gctctggtgg ccctgcacac gccggcgcgg gaaccggtgg accgggacgc
     4861 ggtgacgtac tggcaggact ggcggccgga caccacgggg gcggcgaacg gccggcgctg
     4921 ggtgcgggtg aacgccagca tgttcctcga cttcggccag ttgcggggcc tgtatctgga
     4981 gacgctggcg gcggccgtgc acgcggcgga agccaccgac cccgcacagc acgtcggcac
     5041 ccaggggcat gtgctgacgg caggggatct gctgaccacc ctcgccgtgg aggcgaccgt
     5101 ccaccacctc gacctgaccg tgcggctccc gcacccaccg ggacccgcgc cggagggact
     5161 gaccgcggtg cgggccacgc tggacggtct gctcggccgg cccgcactgc cggagtggag
     5221 tgacgcgcac tacgcgcgcg tgggcaccgg ccgggccacg ctcaccgagg ccgaacggac
     5281 cgcgctgggc gcggcggcgg accgcttccc gctgttcggc tgaggcaccg gctcccgtcc
     5341 gggacggccg tcaactccgg ccgatgtcca gccggttgac tcccccatga acgggcaaaa
     5401 ggctgctccc acaccttgac cgcagtttgg tccagaccaa ttatggccta gaccaatagc
     5461 cccggccggg ccgcacagcg cgccatcccg cacgacaccc gctcgcacgc ctgtcgttcg
     5521 ttcgctaccg ggagtacccg atgacacgtc cgagacccgt acgcgccctg ctcgcaggcc
     5581 tggccacgct ggccgcctcc acagggctcg ccctgggggc cggaggcacc gcacacgcgg
     5641 cgacctcact gcccacgcac gtcttcgcgc cctacttcga ggcctacaac ggcgacagcc
     5701 ctgccgcgct ctcgcaggcc tccggcgcca agtacctgac catggccttc ctgcaggccg
     5761 acaagaaggg ctcctgcacc ccgtactgga acggtgacac cagcaagccc gtcagctcct
     5821 cggtcttcgg cgccgacttc accaccatcc gctcgcgcgg cggcgacgtg atcccctccc
     5881 tcggcggcta cggtgccgac aacgcgggca ccgagatcgc cgacagctgc acgaatgtgg
     5941 actccatcgc cgcggcctac gagaagatca tcaccacgta cgacgtctcc cggctcgaca
     6001 tggacgtcga ggacaactcc ctcacggaca ccgccggcat cgaccgccgc aaccaggcca
     6061 tcaagaaggt ccaggactgg gccgccgcga acgggcgctc ggtgcagttc tcgtacaccc
     6121 tgccgaccac gacgaccggg ctcgccgaca gcggcctcgc cgtgctgcgc agcgcgaaga
     6181 gcgcgggcgc caaggtcgac gtcgtcaaca tcatgacgtt cgactactac gacggcgcca
     6241 cccaccacat ggcaaccgac accgagacgg ccgcgagcgg actgcacgac caactcgccg
     6301 cgctgtaccc gaatctgtca gacagtcagc tgtggaacat ggtcggcgtc accgagatgc
     6361 ccggtgtgga cgactacggc ccggcggaga cgttcaccac ggccgacgcg acgaccgtgt
     6421 acgactgggc ggtctcgaag ggcatcaaca ccctctcctt ctgggccctg cagcgcgaca
     6481 acggcggctg ccccggcggc agcgcctccg acacctgttc gggcatcgcc caggacacct
     6541 ggtacttcac ccacaccttc gcgcccttca ccggcggtac gacgaccccg ccggccaacg
     6601 acttctcggt gtccctgtcc cccgccaccg cctcggtcga ccctggcgcc accgcgacgg
     6661 cgacggtgag gacgtccgtg acctccggcg ccgcccagtc cgtcgatctg gcggtgagcg
     6721 gcgcgccgag cggagtgacc gcctcgctga gcccgtcgtc ggtcaccgcg ggcggcacct
     6781 ccacactcac cgtgaagacc gccgccgcca cgacacccgg cacctacacc ctgaccgtca
     6841 ccggcacggc gggctcgacc cggcacagct ccacgctcac cctgacggtc aacggatccg
     6901 gcggcacggc caccctcgcc aacggcgact tcgagaccgg ctcgctcgcg ccgtggacct
     6961 gcgacaccgg ggcctccgtg gtctcctccc ccgcgcacgg cggctcgcac gcgctgaaga
     7021 ccgcaccctc cgactcacag ccgggccagt gcgcgcagac cctgacgctg aagcccaacg
     7081 cctcctacac actgagcggt tgggtgcagg gcccgtacgc ctacctcggc gtcagtggcg
     7141 gcgccacggc cagtacctgg acctcgtcct cgtcatggtc gaagctcacg gtgccgttca
     7201 cgaccggctc ctcgggcacg gtcacggtgt atgtgcacgg ctggtacggc cagggggcgg
     7261 tgtacgccga cgacctgagt gtgagctgag actgcctgat cctgatccga cccaccgctc
     7321 cgcccggccc cgctcggtga tcaccggcgg ggccgatcca tgcccccgct ggccccccgg
     7381 ctgcccgatc cggcggctcg gagccgtctt ccataggctg aagggaccct cagcgactcc
     7441 gagggggccg cgcagacagg agacggtcgt gatcgaactg gccgcggcgt tcgccgtcgc
     7501 gggagcggcg agcaacgccg tgggcaccgc cttccagcgc aaggccgcgt ccgccagcag
     7561 ccgcggcggg ctccggctgc tcgccgagct ggtgcgccgg ccgctctggg cgatcgggat
     7621 gtgcggggtc gtctgcgccg cgctgttcca gagcctggcc ctggtcaacg ggccgctcgc
     7681 gctggtccag ccgctgttca tcctggagct gcccttcgcg ctgcttgtcg ccgccccgct
     7741 gatgcacagg cggctgcctc gctcgggctg gtggggtgtc ggcggctgtg tgctgggcct
     7801 ggcggtgctc ctgatcgccg ccgccccgca cggagccgtg caccacgccc cgctcacccg
     7861 ctggatcccg gccctgtgcc tgtgcctcgg cgggatggcc gcggccgtac tgctggccgg
     7921 ccggggnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnacgcg ctgaccgccg
     8701 ccctgctgaa gtcggccagc ggcacgttcg ccgaccacgg cttcaccgcg ttcctccggt
     8761 cctggcagac gtacggcttc gcgctgaccg gcatcgccgc ggtggtgctg ctggagaacg
     8821 cgctccaggc cggtccactg gccgcggccc agccggcgct gaccatcggc gacgcggtgg
     8881 tgagtctgac gctcgggatg acgctgttcg aggagcggat ccgcaccggc tggtggctcg
     8941 taccggaggc ctgcagtgcg ctgctgatcg tcgtgggtgt ggtggtgctc agccgggccg
     9001 tccagcacat caccgtggca tcggcccggg ctgccagggc gacagagggt tcttccgggt
     9061 gatcggcagt gtgccggtcg ggtccggccg cgggtggcgg ccgccggact ggagaggggc
     9121 tggcttgcgg agctgatccc gccgacgggc ttctttccgt actttctcaa ccccgcccct
     9181 gccggggccg gccccggcgc tcgacacgga gctggccgcc atccaggaca cccccgtcga
     9241 ccggatcggc cgcgacgtcg atcatctgga ataccaccag ggacacctcg gcccccggct
     9301 gcggtcgctg ctccacgacc cggacacccg tctggcccgc gccacccagg agatccacac
     9361 ctactgggag ccggcgctcg ccccctactg ggcacgcatc cccgcggtac tggacacgga
     9421 cgtcttccac cgggcccgcc aggtcgccga gcacggtgcg ggccacgttc tcaacgacct
     9481 gcacaccgcg gtgagatggg acggcagcac gctgcacctg acccgccgga gtcggcccct
     9541 gtcccgcacc acagcgggcc cggggctcct gctggtcccc tcggccttca ccgggccgcg
     9601 gctgcccacc cgagtcgcac cacccgaacc accacaactc gtctgtccag cgcgcggtac
     9661 gggctcgctc tggactcccg agccccctgc cgacgccgac gccttggccg cggtactcgg
     9721 ccgctcacgg acccgcctgc tgatcgaact ggacaccccg gcctccacca cccagctggc
     9781 acaccgcacc ggactgtccc cggccggggt atcccagtac ctgaccacac tacgtggcgc
     9841 gggcctggtc ggcgcccacc gggcctgccg ctccgtcctc tacgcccgta ccgccgccgc
     9901 tgaaaccctc ctcgaagccg ccttcaccac ctgaggcccg gtcaaccccc gaaggacttc
     9961 cggagccgac cggttgacat cccccgagag ggccctgccg tcagcgcggg tgcgtcagcc
    10021 gtacgtccgc cacgccgagc aggccgagga gcgggacctt gccggtcctc tgacggggat
    10081 cgaccacgag tccggagccg cggaccaggt ccagcagcag ttcggcaagc ggcatcacca
    10141 tgtgtctgcc ccagcagcgt tcggaggagt ggccgaaggg gaggtagccc ggagtcgtct
    10201 cggggtcgag gtcgtcccag cgctcggggc ggaaggtgtc cgggtcgtcc cacagggcag
    10261 ggtcgcggtg ggacagcagt ggcagcacca ggacgtcgtc ccgctcgccg atccggtcgt
    10321 cgacggccgg gtactcgggc gaggcgttgc gcaggatgtt ccacgagggc ggcagcagcc
    10381 gcagggactc gaggatgatg ccgcggttgg gtgtggcgtc gtcgaagggc gcaccgagcc
    10441 agagcgcgtt ggccaccagg gtcgagacgg tgaagcacac gggggcggcg gccctgcggt
    10501 acatgcccat ggcgtaccgg cgctcctggt agccggtggc ccgcgcggca cggcccgcga
    10561 gaccggtgag ccggctgctc ggccgcggcc agccgggcag cgcggcgccg atcgcgatca
    10621 ccgaccaggt gagcttcggg gtgagttcga gattacggct catcagcatg cgcagccggt
    10681 aggggtcctg gccgaggatg aggtcacgca ggaagaggtg cccggtcagc ggccaggagc
    10741 cggcgaggtc cgcgtcctcg ggcagcggtc cggacagtgc ctcgcgcacg tcgttgccca
    10801 gggtgcgggt gacggtggat gcctcggtgc gtgtgatgga acgcccgtgc agtggcttga
    10861 aggtggggcg ctcggtctcc gtcgcccggc gtgcggcgag gatgcgatcg gcgacctcgt
    10921 gtcccgcgac accgaccgtg tcaggttcca gccggaagac gtcctgtcct gtgtgggcgc
    10981 cgatgagcgc ggcgagccgc ggggcgaaca cggtggtgcg cgcacgcgtg gcggaagacg
    11041 gcggcatgga tgctcccggt ggtgaacggg cggccgggga agggcgcgag aggaccggag
    11101 gccgcggaac ggcgtaccac cgctgtccgg ccgggccgtg accacgcacg gccggacaac
    11161 gatgtcacct cacctgcgcg gcgaggcgtg ggatcagtac cagaggtacc aggcgttcgc
    11221 cttgaggctc ttggcggccg cgaccttgtt gcggatggcg aagagaagct tcatcagtgc
    11281 acctcctgga gagggtgaac gggcgacaca cgacgacacc ggagccacta gtgaagatcg
    11341 tgtgtcgatg actccgggaa acttccctcg ccccaccgac gaataatcgc cagagggatc
    11401 aaaaccgttc cggcatagtc actttcagac tttctccgct caccggtgct ccgctttgac
    11461 cacacatccc gccgagcatg ccgtgatgca ccgcccggag attggccgga taggcatgcc
    11521 gccgagcaag gaacgacgca acgcccccgg taacctccgc ttcctaccgt cttcctaccg
    11581 tcccgcgatc ccgtcgatcc aggactggag gcgttcgccc tggacggcca tcaggccggg
    11641 gtcacgcaag gtgttggtga ggacggacat gccctggtag gcggcgacga gctcgacggc
    11701 gagggcggcg gcgtcggcgc ggcccagctg ggtgaactgg gcctccaccc aggcgagcag
    11761 ggcccgcatg acctgcgcgg cggcctggtc caggccgtcg tccctcttgt ccagctcggt
    11821 ggcgagggta ccgaagggac agccgtagcg ggccgcggtc tcgcgctggt cgacccagcc
    11881 ggcgacgagt gccttcagcc gggccgccgg atccgggagt gcgtccaact gagcagtcag
    11941 cgcttcgagt tgctcgcggt gggcgtccac cgtggcgtcg acgagctggt ccttggtctt
    12001 gaagtagtag tagacgttgc cgagcggcac ctctgccgcg cgggcgatgt cgccgagggt
    12061 ggtcttctcc acgccctgct catggaagac ccgtacggcc gccttcacca ggcgctcgcg
    12121 cttgccgccc cggctgccac cctggccgga tcgaccggat cggctcggcc gcgcgacctc
    12181 ggccgtcggc gcggaatttg agtcagtcac ctgactgagg atagacaacg gtcgccatca
    12241 cggactagcg tctcgactta gttagtcaac taactcagat agccaggaga gttgccatga
    12301 tcgttgtcac gggtgccaca gggaacgtcg gacgggctct ggtcgccgag ttgagcgagg
    12361 gtggggatac ggtgacggcc ctcgcccggc acatcgggac ggaggacgtt ccgcctggtg
    12421 tgcgcgccgt tgcggccgat ctcgggcagc cgcagagcct cgctcccgca ctgtcgggcg
    12481 ccaaggcgct gtttctgctg gtggccggcg aggatccggc cggcattctg cgccaggccg
    12541 ccgcggccgg ggtcgccaag gtggtgttgc tgtcctcgct gggggcgggc acccggcctg
    12601 agacgtacac gcacgcgacg cgcttcgagg cggccatggc cccatcgggg ctgcccttca
    12661 ccgtcctgcg ctcgggcggg ctggcctcca acgcgctggc ctgggcggag ccgatccgcc
    12721 ggtaccgcac cgcggcggca cccttcgccg atgtggcact gccgtttgtc gatccggacg
    12781 atgtcgccgc ggtggcggcg gccgtgctgc gcggagacgg acacgacggc gccctctaca
    12841 cactgaccgg cccggagccc accacccccc ggcagcgggc cgccgccatc gcggccgtgc
    12901 tcggcgagcc ggtgacattc gtcgagcaga gccgcgagga ggcccacgcc cagatgatcc
    12961 ggttcatgcc ggccgccgtc gccgaaggca cgctcgccgt cctcggcgca cccacaccgg
    13021 aggagcaagc ggtcggcacg gacgtggagc gtctgctcgg ccgccccgcg gcccccttct
    13081 ccgcgtgggc ggcacggcac gtggcggcgt tccgctgatc ctccgcatga ccccttgggg
    13141 ccgaccgggt gacacgagtg acgcctgaca acacctttga caacaccttt gcacgccaca
    13201 ccgcaccaga tcggcccttt tatatgttta tcgcacttat ggtgcgggtg ttggaagctc
    13261 gaccgagggg ggtgcacaac gcgtcgcggc agggcgcgga tggggatggc gatgggtgga
    13321 atcagccgac ggaatgtggc acgcctgggg ctcggcgccg gcatcggtgc ggccgccgcc
    13381 ctggcggcgt tcggaggaca ggacggaccg agcggctcgc cagggggccc gaaaggacag
    13441 ggcgcggcgc cccggcaagg ggcactgcgg ctgatcgggg acggctcgac ggcgtacacc
    13501 ggacggcagc cgcaccagcc ggagccgccc gcgcccctcg aacccggcga gactcccccg
    13561 cagttcgtgg tgttctcctg ggacggggcg ggcgagttgg gcaccggact gttcccgcga
    13621 ttcctggagc tcggccgcac ccacggcgcg cacatgacgt tcttcctgtc cgggctctac
    13681 ctcctcccgg aggggaagaa gcggctctac gatccgccga acaacccggt cggggcctcg
    13741 gacatcggct acctcaccga cgcccacctg aaggagacac tgaagtacgt gcgtcaggcc
    13801 tggctggacg gccacgagat cggcacgcac ttcaacgggc acttctgcga ggggcccgga
    13861 tcggtggcca actggactcc ggagcagtgg cgttcggaga tcgagcaggc gcgggcattc
    13921 gtcacgtcat ggcgcacgca caccggctgg cacgaccatc cgcccctccc cttcgactac
    13981 gacaaggaac tcgtaggcgg ccgcaccccg tgcctcctcg ggcaggcgaa cctgctgccg
    14041 gtcgcgcgtg aactgggctg gcgctacgac gcctcctcgc cgggcgggct gcaacgctgg
    14101 cccaggaagc ggcacggtgt ctgggacctg ccgctgcaga gcatcccgtt tcccgggcac
    14161 tcgttcgaag tgctgtccat ggactacaac atgctggcga accagtccaa gaactcgacg
    14221 cgggcacctt cctacaacta cccgtactgg cgcgcccagg cgacacaggc ctacgtggca
    14281 gggttccaac gagcatacga gaccaaccgg gcgccgctgt tcatcggcaa ccacttcgag
    14341 cagtggaacg gcggcatcta catggacgcg gcggaggagg cgctcggaca gatcgccggc
    14401 cgggaggatg tacgtctggt ctccttccgc cagttcgtcg actggctcga cacccaggac
    14461 cccgcaatcc tccggcaact ccgcaccctc caggtcggcg agaagccgag cgccggctgg
    14521 gccgctttcc tgcaccccgc ccagaggacc tgacaagccg gtcctccggg ccgacgcccg
    14581 acctgccgga agtacgcgag gcgcgtggac aggcccgaca ggccctgttg ccatgcccgt
    14641 ttcccctctc gatttccttg accgtccatc cggtgagagc tgtttcacga tcccttggtt
    14701 gcttcgtgga atagttttta cattcgagcg tggatgagga tagggttcaa gatcgcgaca
    14761 gaccgggcca ctgaccacgg atggggcgcg cgctcccgga gttgctgttt acgcaagcca
    14821 ctttggcgtt gtcgtcgttg tcgtcccttg caccaggagg tgtcatgcat tctgctcggt
    14881 tgtctcgggc cgctctgttc accgtgctgc tcctcaccgt cgagaccgcc tgcacgagtt
    14941 ccggcggtcg ccccgacgaa gcccccaggc ctggtgcggt ttcggcagga gacgccttgt
    15001 ttcccgcgtt gggcaacagc ggctacgacg tcgcgcatta cgcgttgaca ctcgactacg
    15061 tcccggagac caacgagctg gccggcaccg cggtgatcac agcccgggcc gaacagcccc
    15121 tgagccgctt ctccctcgac ctcgcgggcc tgagcgtgcg cgacgcgagc atcgacggag
    15181 ccgacgccgg ggtaagcagc aagaagaaca aactcatcct cacgcccgct catccgctca
    15241 agaccggcgc gaccttcacg accaccatcc actactccgg caccccgaag atgttcaccg
    15301 ctgcggacgc aagcgtggag gggtggatcg aaaccgacga cggcgcggca gcgctcggag
    15361 aaccgacagg ctcgatggcc tggttcccgg gcaaccatca tccgtccgac aaagctctgt
    15421 acgacatcac catcaccgtc cccaagggct acacagcagt cagcaacggc gaactgaccg
    15481 ggatacggga caaggggcgg cgtacgacgt cacgttggca tatgggtgag ccgatggcca
    15541 gctacgtcgc aaccgtcgta gtgggcagct tcgacatatc caccacgacc accgcgcagg
    15601 ggctgccggt atacatcgcc atcgaccccg acgaggtcga ggactccccc gacatggccg
    15661 agctgatccc ccagatcatc gactgggcag gcagccggtt cggccgctac ccctttgcca
    15721 gcaccggggc gatcgtcgat catctccccg atctcgagta cgcgctggag acccagacca
    15781 agccgtactt cgagaaggcc cccgacgaaa cgctggtcgt gcacgaactt gcccatcaat
    15841 ggttcgggaa ctccgtcacc cctcgctcct ggcaggacat gtggctgagt gaagggttcg
    15901 ccacctacgc cgaatggatc tggcaggaag accaaggcga cacgaccgcc gatgagatct
    15961 tcaacgcctt ctatgacggc acccaccccg aaagcgaggg gatctgggac ttccctccag
    16021 cgcaaccccc aagcgccaag caggtgtccg actctcccgt ctacggacgc ggggccatga
    16081 ccctccatcg tctccgcgaa accgtcggcg acaacagctt cttcaccatc ttgaagacgt
    16141 ggaccgaaca acaccggtac ggcaacgccc acaccaccca gttcatcaag ctgtgcgaga
    16201 aagagtccgg catggatctg actgaactct tcgacacctg gctctacggc gaggaaaagc
    16261 cgactctcgc gtagccgttt catcgagtag aggacggaaa agggcacaag tgcacggcct
    16321 acggtaaatg gggcgggtac cgccagcccg tctccttcca cccgtaccgg gggagagagc
    16381 gtggccggcg cgctggagac gcggacgcgc aagtctgcgg gcacctgaca cgcggctttg
    16441 cgtgtccacg tgcgtttctt ggtcaggaca cggcacggac gtccgctcct gtacacgttc
    16501 tgcccttcgg atgtccccgc acggaccatg ccaccccctc ccgcactgcc tgaggagaac
    16561 ccttgatccg acgttcggcc cgtccggccc gtccggcccg tacggtcgtc gcggcagccg
    16621 ccgcgctcgc cgccaccagc gcgctcaccg ccacggccat cgagcccgcc tcggcgcaca
    16681 cgcccggaca cccggccgcc cggcacgtcc tgctgctgtc ggtcgacggc ctgcaccagt
    16741 ccgacttggc ctggtacatc gcccgccacc cgcactcggc actcgcccgg ctcgcgggag
    16801 gcggcgtgga gtacacacac gcgagaagca ccatcccctc cgactcgttc cccggcatgg
    16861 tcggccagct caccggcggc aacccgggca ccacgggcgt ctactacgac gacggctacg
    16921 acgccgccct gctcccggcc ggcaccacca agtgcgcggg cgccgagcgc ggcgccgagg
    16981 tcgacctcac cgaggacctc gacaagaaca aggactccat cgacgcgggc cagggcctga
    17041 ccggactgcc cggcagcatc ctgaagatga ccggtcacgc cgcgagcctc atcgacccga
    17101 cgaagctgcc ggtcgacccg aagtcctgcg cgcccgtctc cccgcacgcg tacctgcggg
    17161 tgaacacggt cttcgacgtg gcccgcaagg ctggactgcg gaccgcgtgg tccgacaagc
    17221 acgtggcgta cgacatcctc aacggcccct cgggcaacgg catccaggac ctgttcgcgc
    17281 ccgagatcaa cagcaccgcc atcggctacc ccgcgggcga cgactggacc aaggacaacg
    17341 cggcgaccga gcagtacgac ggctacaagg tgcaggccgt gctcaacgag atcgacggct
    17401 atgaccacag cggcacccac aaggtcggca ccccggcggt attcggcatg aacttccagt
    17461 ccgtgtcgac cgcccagaag ctgccagcct ccgacggact ggccggcggc tacaaggcca
    17521 agggggtgcc cggaccgctg ctggagaaga acctcgcctt cgtcgacagg gaggtcggcg
    17581 cgttcgtcgc cgagctcggc aagcggcacc tggacggcag caccacggtc gtcctgtccg
    17641 ccaagcacgg ccagtcgccg accgacccga aggcgctcac ccgcatcgac gacggccccc
    17701 tcctggacgg cctcaacgcc gcctggaaga aggctcaccc gggctccggc gacctggtcg
    17761 cgcacgccgt ggacgacgac gccatgctga tctggctcac cgaccgctcg caggccgcca
    17821 ccgacttcgc caaggcgtac ctgctcgccc agtccggcac cggcaacggc atcgacggca
    17881 acgccaagct cttcacggcg agcggcctga acgccctgta cgcgggcgcg gacgccgccc
    17941 ggtacttcca tgtgaagccg ggtgactccc gcgtgcccga cctgttcggc atcacccagt
    18001 acggcgtcgt ctacacgggc ggcaagaaga agatcgccga gcacggcggc gcccacgccg
    18061 acgacctcga cgtccccctc gtcgtctccg gcgccgtcat cccgcacgac gtccgggtcg
    18121 ccgcaccggt cgagaccacc cagatcgccc cgaccatcct gcggctcctc ggcctcgacc
    18181 cgcgagccct ggacgccgta cgcgccgagc acacccccgc actgcccgtg cgctgatctc
    18241 tcgggctgcg ggctggggag ccgctcgctg ggctccccag cccctggccg gtccacaaca
    18301 ccaccgagag cggccggctc atagcgctgt gatcagcagg tgcgccgcca gtgcggtgat
    18361 cagtgtgctg gagacaagtg cggtcaggag ccgcccccgg gtgccggtca ctgttcggcc
    18421 gagcagtgct ccaccgcttg ccagaagcag ctgccagctt gccgatgcga cgaaggccgc
    18481 gagaacgaac gcggcttgct ggaagtggtc ctgaacggct gtgccgcgac tgcccagcac
    18541 gagtgccgcg aagtagatca cggtcatggg gttcgtcatc gtgatcccca agagtcccgc
    18601 atacgcccgg gctgggctga gggggatctc atcggtccgg gtcgtcggct tgtgctcgcg
    18661 atagtggcgg atcgccgtgg cggcactgcg gacagccagc acgagcagta cacaggccga
    18721 ggcataccgc aggggaagca tgatcggttt gatcgtcggg acgagggcgg cgccgccgaa
    18781 cgcggcgatc agggcataca ggccgtctgc ggtcgcgacg cccagcgcgg cacaggcgcc
    18841 gactttccag gacgtccgag cggtcagagc cacgagatag gtcgcgaccg ctcccaccgg
    18901 gacggcgatg ccgtagccgg caaggagtcc cgcggccaag gcgccggtca tgccggcagg
    18961 agcgtcggcc ttcgcggtcg gcccggctgc tgctggactc gcaccggccg atcggcggag
    19021 ggcaacggca gcggggcggt ggtcgtgatc ataggcagat cttgtgggtc atgcggttcc
    19081 cgggcaaccc gattttccgg gagcacatca gtggacaaag ctggcgaaca ttgcgagcag
    19141 ccgctgttcg gcaccgacgt ggcctagagt cgccgcatgc gacgagggac ggcactggcg
    19201 gtcgccgggg cagcggccct ggcctggggc gagtggttga actggcgctg gtctcgcgca
    19261 ctcctgggga gcggtggggg cgcttccgaa gccgtggtgg tgctgggtta ccgaaacccc
    19321 caggcgacgg cgaacttgat caaccgctgg cgagtccgtg ctggaattcg ctcgatcacc
    19381 ggcgacagtg cgcgtgacac tcgcgtgatc ttcagcggcg gcgcgacgac cagcggaggc
    19441 gctgcggagg cgcggttgat ggctgactac gcgaagtcgg tgctcgagtt cgacggcaca
    19501 gtggtcctcg aagaccaaag caggacgaca tgggagaacg tcatgaaagt gaccccactg
    19561 ctcgaggacg ccgaccgcat caaaatcgtc tcccaaccgg ctcatgcgct caaggcccgc
    19621 gcgtacttgc ggcgacagcg ccctgatctt gccgtgaagc tcgtacgcgc ggatgactac
    19681 cgccccggcg agtggatgat cgtcaaaccg ctgctggctc tgtacggact ctggacactc
    19741 cgcggtctca aagccggcga gcggaagatc tcgctctagc cggccgctgg cgcgtggtcg
    19801 tagccgcgat cggccaacac ggcgtccagg cggtgccggg gtcggccgcg cttgcctctc
    19861 acgggcgcac ggcttgaagc agcgggatca gcccgggcga cgtcgttgcg attgccgcag
    19921 gcacgcgggg ggggagccgc ccgcgacggg gaacgcgggc ggtgctcggg tcagtgacgg
    19981 ccggagaaga gggttacggc cgtctcggcc accaggccgg ggcgttcctc gtggaggtag
    20041 tggccgcagc cggggaccac ttggacgcgg aggtcgtcgg cgtggcgccc ggcgtcagtg
    20101 atgacgctcg gcggcagcat gaagtcccgc tcgccggcga ggatcacggt cggcgtggtc
    20161 agccggagcc tcttgtaccg gccgaggacc agcttggcga tgtcccgcag ggcgaacgcg
    20221 cggtgcagcg cctccccggc ccgcgcccgg ccgggctcct ggctggagcg cacgaactcc
    20281 cccatggcac ccggtgtcca tacggcctgc tccaccactc ccttgcgcat caggtagcgc
    20341 gtgaaaccgg gccggttgcg cagcatccag cggcccagca gcggctgttc cagcaccgcc
    20401 gtgtaccaga accgccagga ctccggcatc agccgccggt gcagcggcca ggggtgcatc
    20461 atgttcagcg ccaggtggtg ccggatccgc tccggggccg tgagacacac gtggaacccg
    20521 gtccacgcgc cccagtcgtg cccgatgaga tggacccggt ccaggcccag ttcgtccaga
    20581 aggccgagca cgtcggcgac ccggctgtcg gtgtcgtagc cctggtgcgg ggcatcggac
    20641 cagccgaaac cgcgctggtc cacgcagagc agccggtacc ggccggacag cagcgggatc
    20701 agctgccgcc agccgtacca gtgctggggg aatccgtgca gcaggacaac gggttctcct
    20761 tggccggcct ccgcgatgtg caggcgcaga ccgcgcacgc tgacataacg gtggcggact
    20821 ccgtccagtt cgggcaacgg cgggatgtgg tccacggtct ccacgagtgc tccagtcagg
    20881 tgttggaggg agctggtcgg cctgtcagga gtcgccaggc gcgcgaaagg ttccgtccgt
    20941 cccccgatcg atgccaccgg cgggctgcac gaggtgttct tcctgcgcct ggcccgctca
    21001 tggcagtcgg tatcctgggt tttccggact cgaacgaggc agcgtgg
//
