LOCUS       NZ_CM002273            34673 bp    DNA     linear   CON 11-AUG-2024
DEFINITION  Streptomyces sp. PVA_94-07 strain PVA 94-07 chromosome, whole genome
            shotgun sequence.
ACCESSION   NZ_CM002273
VERSION     NZ_CM002273.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. PVA_94-07
  ORGANISM  Streptomyces sp. PVA_94-07
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7007517)
  AUTHORS   Ian,E., Sekurova,O.N., Malko,D.B., Ruckert,C., Borisova,M.E.,
            Albersmeier,A., Kalinowski,J., Gelfand,M.S. and Zotchev,S.B.
  TITLE     Draft sequence of Streptomyces sp. PVA 94-07, a marine actinomycete
            isolated from the sponge Phakellia ventilabrum collected in the
            Trondheim fjord (Norway)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7007517)
  AUTHORS   Ian,E., Sekurova,O.N., Malko,D.B., Ruckert,C., Borisova,M.E.,
            Albersmeier,A., Kalinowski,J., Gelfand,M.S. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAY-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Assembly Name                     :: PVA94-07.23
            Genome Coverage                   :: 158.81x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000495755.1-RS_2024_08_11
            Annotation Date                   :: 08/11/2024 02:29:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,173
            CDSs (total)                      :: 6,079
            Genes (coding)                    :: 5,859
            CDSs (with protein)               :: 5,859
            Genes (RNA)                       :: 94
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 220
            CDSs (without protein)            :: 220
            Pseudo Genes (ambiguous residues) :: 0 of 220
            Pseudo Genes (frameshifted)       :: 97 of 220
            Pseudo Genes (incomplete)         :: 166 of 220
            Pseudo Genes (internal stop)      :: 15 of 220
            Pseudo Genes (multiple problems)  :: 55 of 220
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:06:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2603847
            Orig. end                         :: 2638520
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002273.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Department of Biotechnology,
            Norwegian University of Science and Technology, 7491 Trondheim,
            Norway.
FEATURES             Location/Qualifiers
     region          1..34673
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /product="RRE-containing"
                     /region_number="14"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..34673
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="interleaved"
                     /product="azole-containing-RiPP"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..32461
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:22461](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..22461)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            141..506
                     /locus_tag="B590_RS31005"
                     /old_locus_tag="B590_10960"
     CDS             141..506
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="B590_RS31005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_10960"
                     /product="ATP-binding protein"
                     /protein_id="WP_230536946.1"
                     /transl_table=11
                     /translation="MREARATARRLLPWLGYRGELDAPVLIVSELVTNAVEHGSSLEDT
                     ALLLRLSVHPCGGLSVEVTDGGTTPPGPPAPPPCPEAESGRGLFLVHALGARTTWEQAA
                     TGKTMRAFLPLGGTVPR"
     gene            503..835
                     /locus_tag="B590_RS10850"
                     /old_locus_tag="B590_10965"
     CDS             503..835
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642989.1"
                     /locus_tag="B590_RS10850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_10965"
                     /product="hypothetical protein"
                     /protein_id="WP_023417519.1"
                     /transl_table=11
                     /translation="MTAAGASHRWPDPDLLCMEALRVLSDAADAALAGQGLSARQASQL
                     AAWLRALCESYGEATHPAVVAAVRAANRALGPGVSPVLTLATHARGLLDLTFRLRAEGR
                     PVHPGA"
     gene            complement(861..4394)
                     /gene="mfd"
                     /locus_tag="B590_RS10855"
                     /old_locus_tag="B590_10970"
     CDS             complement(861..4394)
                     /GO_function="GO:0003684 - damaged DNA binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="mfd"
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018889817.1"
                     /locus_tag="B590_RS10855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_10970"
                     /product="transcription-repair coupling factor"
                     /protein_id="WP_023417520.1"
                     /transl_table=11
                     /translation="MSLHGLLDAVTEDPALTQALKAAGDGHLLAADLVGPPAARPFTVA
                     ALARETGRTVLAVTATGREAEDLAAALRTLLPPDGVVEYPSWETLPHERLSPRSDTVGR
                     RLAVLRRLAHPDADDPETGPVSVVVASVRSVLQPQVKGLGDLEPVALKAGQTTDLEEVV
                     RALAAAAYSRVELVEKRGEFAVRGGILDVFPPTEDYPVRIEFWGDEVEEIRYFKVADQR
                     SLEIAEHGLWAPPCRELLLTDQVRERAAALAVDHPELGELLGKIAEGVAVEGMESLAPV
                     LVDEMELLLDVLPEGAMALVCDPERVRTRAADLVATSLEFLQASWAASAEGGEAPVDVG
                     AASLWGIADVRERARELGMMWWSVSPFAADEETYDGDTWQLGMRAPETYRGDTARALAD
                     TKRWLGEGWRTVFVTEAHGPAARTVEVLGSEGVPARLDGDLGEISPSVVHVACGAIDHG
                     FTDERLKLAVLTETDLTGQKAAGKDGQRMPTRRRKTIDPLTLEPGDYIVHEQHGVGRYI
                     EMVQRTVQGATREYLLVEYAPAKRGQPGDRLYIPTDQLEQVTKYVGGEAPTLHRLGGAD
                     WTKTKARAKKAVKEIAADLIKLYSARMAAPGHAFGQDTPWQRELEDAFPYMETPDQLST
                     IAEVKDDMEKTVPMDRLICGDVGYGKTEIAVRAAFKAVQDGKQVAVLVPTTLLVQQHFG
                     TFSERYAQFPVNVRALSRFQSDAEAKATLEGLRDGSVDIVIGTHRLFSSETRFKDLGLV
                     IVDEEQRFGVEHKEQLKKLRANVDVLTMSATPIPRTLEMAVTGIREMSTITTPPEERHP
                     VLTFVGPYDPKQIGAAIRRELLREGQVFYIHNRVESIDRAAARLREIVPEARIATAHGK
                     MSEQALEQVVVDFWEKKFDVLVSTTIVESGIDISNANTLIVERGDNFGLSQLHQLRGRV
                     GRGRERGYAYFLYPPEKPLTETAHERLATIAQHTEMGAGMYVAMKDLEIRGAGNLLGGE
                     QSGHIAGVGFDLYVRMVGEAVADYRAALDGGVEEEPAPEVKIELPVDAHVPHDYAPGER
                     LRLQAYRAIASATTEDDVRAVREELTDRYGKLPEPVENLLLVAGLRMLARSCGVAEIVL
                     QGNNVRFGPVELRESQQLRLNRLYPRTVIKANTHQILVPRPTTGKIGGKPVVGRELLSW
                     VGEFLTSIVGS"
     misc_feature    4680..4694
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 13.79"
                     /tool="antismash"
     misc_feature    complement(4739..4754)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 16.83"
                     /tool="antismash"
     gene            4824..5828
                     /locus_tag="B590_RS10860"
                     /old_locus_tag="B590_10975"
     CDS             4824..5828
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507247.1"
                     /locus_tag="B590_RS10860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_10975"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_241193504.1"
                     /transl_table=11
                     /translation="MGDNEMAVFGLSATEEELYRHFLRNPGTCADDVHLLLRTADRAGK
                     DAARALDRLRELGLLLPAGPDGRVVPADPEQAVSHLTDRRLHELHQDLRRVTRSRHVVD
                     GLRAEQGARTAAPQGIEQIEGLAAIRGRIEDLAFFAREEILSVEPYTRLSPENITRSRP
                     LDLRCLARGVTIRNVVRHSALADPPTAAYLRELAAAGAHIRVADEGEAGERLLVYDRRS
                     VLVPLDPRDTARGALLAHKSGLVANIIALFEKIWAQAAPLDDAAGQHGESPLSEMERRV
                     LLAMCTVGKDEAGARELGVSVRTYRRHVADLMQLLGAASRAQAALLARERGWV"
     gene            complement(5830..7248)
                     /locus_tag="B590_RS10865"
                     /old_locus_tag="B590_10980"
     CDS             complement(5830..7248)
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895321.1"
                     /locus_tag="B590_RS10865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_10980"
                     /product="amidase"
                     /protein_id="WP_023417522.1"
                     /transl_table=11
                     /translation="MQDDALWRMTATAQAAAVRGGQVSAAELTDSHLARIEAVNPRVNA
                     VTQLWADRAREEAARLDRRRAAGEELGPLAGVAFTVKESTPVEGVPTTFGAERFRDLVA
                     RADALPVARLRAAGAIPVGHGNIPTMILAGMHTRSELFGDTVNPWDPARTPGGSSGGDA
                     VAVATGMAPLGLGNDSGGSVRIPAQFCGVAGLKPSTGRFPADHRVIGPDDPGLASQLLV
                     TDGPLARSVADLRLAYEVLAGTDPRDPRAVPVPAYGERLPGPLKVAVVADPGGHGVHPS
                     VRQAVARAADALRDAGYELCEVPDVPRLDEALEVYGRITITEFAPSWPVVRTLLGPGGD
                     RYIAEAMEETPPATAGELTALTGAWLGIRRCWAEFLDAYPLLLGPVFTEPPVEPGLESR
                     NRAGRERVGTGMRLCTATSFAGVPGVAVPTGLVDGLPSGVQVVGRAFREDLCLEAAQAI
                     EDRLGVLTPLDPRP"
     misc_feature    complement(7277..7295)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.21"
                     /tool="antismash"
     gene            7382..7996
                     /locus_tag="B590_RS10870"
                     /old_locus_tag="B590_10985"
     CDS             7382..7996
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008410243.1"
                     /locus_tag="B590_RS10870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_10985"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_023417523.1"
                     /transl_table=11
                     /translation="MPKQVDHAERRRLIAGAVCRLADERGLEGVTLRDVAARAEVSMGA
                     VQRCFRTKEEMLAFTLGQIGERVTGRVRARLVESPAQSARTALGHAAEETALLRGEDRA
                     EARVWLAFVAQAAVSPALARTLRADYARLQEAFTGLVREALADLGHPAPPDARRAARTL
                     LALADGLTTHVLVGHLTPEEAYDVLHAHLAGLWEAPPGSAD"
     gene            complement(7985..8245)
                     /locus_tag="B590_RS10875"
                     /old_locus_tag="B590_10990"
     CDS             complement(7985..8245)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642996.1"
                     /locus_tag="B590_RS10875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_10990"
                     /product="hypothetical protein"
                     /protein_id="WP_023417524.1"
                     /transl_table=11
                     /translation="MTPRLPAHLDVTLHRADPAAPPGQITVIRLLALLPADWCCHPDAG
                     TDQLRLRVRPAPAEPGPALARALADPALCGWGMAGRGASVR"
     gene            complement(8242..9540)
                     /locus_tag="B590_RS10880"
                     /old_locus_tag="B590_10995"
     CDS             complement(8242..9540)
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895323.1"
                     /locus_tag="B590_RS10880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_10995"
                     /product="amidohydrolase"
                     /protein_id="WP_023421889.1"
                     /transl_table=11
                     /translation="MTPVAAPETQPPRAEVKAAVELYLALHRAPELSGAEHATAALLAD
                     RLTALGLTVHRGLAGTPSFLAELRNGPGPTVLIRTELDALPVTEATGLPYASTVPGAMH
                     ACGHDLHAAAALGAAARLAATRAGWRGRLLLLGQSAEETLTGARALAEDGLYDRFGRPD
                     AILAQHAAPLPAGTVAHAAGGPLMAGSRTLDAVLHGRGGHAATPHLAADPLLMAASAVL
                     RLHTLTARETAPAEGAVLTVGTLHAGTRANVIPDRATLSLGLRAFTEPALDRLHEAVRR
                     VLDAESEAAAAPRPPELALTARSPVLTPDPALTAALRTVHTAHLGAGRVLAAAPSPATE
                     DLTHLTALPDGTHVPLAYWMLGTTPAATWRAAAAEGRTVPANHAPDFAPDLRQALPTGV
                     TALTAAARHLLAAGPPTVGAVPVPVPPHPEVAP"
     misc_feature    9611..9628
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 13.62"
                     /tool="antismash"
     gene            9741..9917
                     /locus_tag="B590_RS10885"
                     /old_locus_tag="B590_11000"
     CDS             9741..9917
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003968635.1"
                     /locus_tag="B590_RS10885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11000"
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_026048345.1"
                     /transl_table=11
                     /translation="MTPKTELATLADEILELESETFEISDYSDAAEVVLAGSTSCSSTS
                     TCSSTTSTTSCSA"
     misc_feature    complement(9769..9783)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.68"
                     /tool="antismash"
     gene            complement(10001..12010)
                     /locus_tag="B590_RS10890"
                     /old_locus_tag="B590_11005"
     CDS             complement(10001..12010)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643001.1"
                     /locus_tag="B590_RS10890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11005"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_023417526.1"
                     /sec_met_domain="TIGR03604 (E-value: 3.6e-93, bitscore:
                     310.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 1.8e-69, bitscore: 233.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPATPAPTTTPPALSPPAAPRPLDAARDQLQAALTARHAALPEAE
                     RALLPAPSVVPLGAADTLGTGAPDPYAAARRSATVHLTSRAVLTGPWLPEGADAETAGA
                     CGQCLAMRWQRLRGRTEREALERRHVPYGATGWPLVTDWAVEAVWAAYRAVHRPGRTAP
                     EAEEPADRTLPRVTRTDLVTLATATFPLLPDPLCPACVTPRPDTAERARLTLEPAPKPD
                     PATYRVRSLGAYALPVAALANPVCGALGSDTWINPASTTTAPVAGTHFVRGYAGLTDVT
                     WSGQANRTATSRRLAFLEGLERYAGTHRRRGTTPVLGSYHQLASDALDPRTCGVYAPET
                     YANDPLVSPFDPDREIPWVWGHSLRDERPVLVPARLAHYSAGVDADNFVFECSNGCATG
                     SGLVEAILFGLLERVERDAFLLAWYGRARLTEIDLATLTDPEVRAMTGRAALHGYDIHV
                     YDTRMGPPVPVVTALAVRRDGGPGTLAFAAAAGFDPAETVASALSEVLTYIPHLPYQVT
                     ERRAELTAMAADFTLVRELKDHAQLYGLPGMAHHAAPFLDPLDRLPLAEAFADWDAVRP
                     RTGDLRDDLALLTGALADAGHDVIAVDQTTPEQARAGLSTVATAVPGLLPIDFGWTRQR
                     ALTMDRLRTGLRTAGRRADDLPAGAVHLAPHPFP"
     gene            complement(12111..12866)
                     /locus_tag="B590_RS10895"
                     /old_locus_tag="B590_11010"
     CDS             complement(12111..12866)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609025.1"
                     /locus_tag="B590_RS10895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11010"
                     /product="ABC transporter permease"
                     /protein_id="WP_023417527.1"
                     /transl_table=11
                     /translation="MSAYAALSQAGYRAYTRDKTTLFFTFAFPLIFLVVFGLIFSGQEV
                     EQSGRPYISYIAPGVLSWGLGNAAVFGVGFVLMQWRRDDILRLIRMTPTPTSAVLASRY
                     VLALGIGAVQAVLFVAVAMLPPFGLELSSGWPYAFLMLVVGVTAFLALGVIVGSFTRTP
                     EAVAAVANCVMLPMAFLSGSFFPLDAMPGWMQAVSRVLPLRYLNDGVSASLTGSGTTGD
                     ILVSCAVLAGFAVVFTAVALKTFRWSDRT"
     protocluster    12451..34673
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[22450:24673](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(22451..24673)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="2"
     gene            complement(12915..13856)
                     /locus_tag="B590_RS10900"
                     /old_locus_tag="B590_11015"
     CDS             complement(12915..13856)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643003.1"
                     /locus_tag="B590_RS10900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11015"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_023417528.1"
                     /transl_table=11
                     /translation="MTPQPTDPAGAVVLDGVRKTYGRTEAVAGVTLTVARGEFFGLLGP
                     NGAGKTTLVEIMEGQRKADAGTVTVLGHHPWPRDTALLPRIGVQTQSSAFFVRLTAREH
                     LTTVAALYRVGREAAEKALALVGLTDHGDVRVDDLSGGQRQRLAIASALVHEPELIFLD
                     EPTAALDPQARRDLWKVLRDLKGAGRTIVYTTHHLDEAEALCDRVAILVGGAVRALDSP
                     GRLIAASSGTTRLLVPADRLTPGQGAALPGVLRATADGDMTVLETEDSGPVLAAVDAQG
                     GLHGVQTRTPSLEDVYLALTGEASLAPAPAES"
     gene            complement(13907..15025)
                     /locus_tag="B590_RS10905"
                     /old_locus_tag="B590_11020"
     CDS             complement(13907..15025)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950321.1"
                     /locus_tag="B590_RS10905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11020"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_023417529.1"
                     /transl_table=11
                     /translation="MSAPAERAAVPGSYRPALRAGVLVGGPLYDGPATVHLVKDTATGH
                     AFKAGPREAFLLARMDGTRALDQLGTEYAAAHGKRLGEAQWRQLLALLGTRGLLDGAPR
                     PAAAPLAPAEPRTLWRGTLRLVADADATTARLHRVLRPLLHPAALVPLLLLVLALQAAL
                     VLRAGEALDATWALFQNPVLLVAAATLLWLSTALHELAHGVVARHHGGTVAEIGLRWRL
                     PVVIMYCTVDNYPYLPTRWARIATAVAGAVMNLLFLLPFGALWLLAPPDDATRDACAAL
                     VLLGTVQALAMLIPLPPLDGYQIAGQLTRTLGLFTASRTYLGLALRRDPAARAYPAPAR
                     RAYLAYPAAVLLVLAGTGLALWAAARHLLTGS"
     gene            complement(15022..16089)
                     /locus_tag="B590_RS10910"
                     /old_locus_tag="B590_11025"
     CDS             complement(15022..16089)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018471574.1"
                     /locus_tag="B590_RS10910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11025"
                     /product="lantibiotic dehydratase C-terminal
                     domain-containing protein"
                     /protein_id="WP_023417530.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.3e-106,
                     bitscore: 353.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLTLTGTRAATKSGAWQATHVFYAANPRPFLLTCVRPLVAELE
                     AEGLISGYFFINYWLEGPHVRLRLKPATPQAEAEVRRRTEGAVDTFLRERPALYEVDAG
                     FLNDFYNTLFDIEFPGAERGHYTGADGRMNIRPNNSRSAEPYEPEYGKYGGPAGIELAE
                     WHFRHSSDLVIDAFATINLHLRTVLLGTSAQLMMVMAATFLPDKAELNGYLDSYYEFWH
                     RAFPGTNFIGTDEYDRNYAALAPGLGERFARVRAATAPATEEGEKPRLPGFLASWAEHC
                     AELKEKAEKLTLDGDLIFRSWDGTRDEQVTDPAVALPLLLSPYMHMTNNRLHVTIRDEA
                     YLSHVLGRVLREGTA"
     gene            complement(16086..18851)
                     /locus_tag="B590_RS10915"
                     /old_locus_tag="B590_11030"
     CDS             complement(16086..18851)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895328.1"
                     /locus_tag="B590_RS10915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11030"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_023417531.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.2e-55, bitscore:
                     185.5, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSGRGTPAAMPAPDAPAPRPGRPREAFVLRTAGLPVETVRPLRA
                     PGARRWADDVLDAAARLTADGEALGDLLHPLIGGLQDEAERRALLKLRREVFNNRLPKD
                     PGAARALVAARDPRTAEALTGWLERRAALAAREAEGAGLLASETARARAALCAAAGQDR
                     LRKGLLLASPTLDAGLDAYVRRTAAEPAATPDKKHRKIERSLLSYLYRTACKTSPFSTF
                     TGVGLGTFSEGEPHEGPGAFPLAVADAWPTAARLNTAAVGRLAATVLADPGRRADLPVT
                     VASGWGREADRVRYVRRWVTEGDEATAVTFDSVKDRLFYLRRSGTLDRLLGHFEEHGTL
                     RYGALSAWLAADRDATEADVAQYLDALLALGLVRVPCLDVTVHDTDPLRAFQSALRGVG
                     RVWADRLADRLEPAAACVDKFAAAEPDRRRLLLEQLRGELAAVQRSLGAEQRRVPQTVL
                     YEDCAVPADGPTGLTLSAGRWAEIAGEPLSRLERVLPAFDLTLPHRLTFKGFFTARFGR
                     GGRCDDLVKLVHDFHEDFFDQYLSFTAQRPAFGPDGDHNPEENWLGLPELKSLDAARAT
                     FLAGMRERWAAHEGDGDLVLDDALLDATAAPLAPLAPAFAPMSHHVQLADRPEGPLAVL
                     NRSYGGLSFPFSRFTHLFEGLDERLLAAGAQAAPPGAVLAEVTGGPVTSNLNLHARLTE
                     YEIVGPGEAGTLEPEFRLGLDDLFLVHDEEEDRLVLRSARLEREVIPVYLGYLVPLALP
                     ELPRTLLLLSPTSMSPLNVWGGVPDRPPVDGVTHRPRVRHGSLVLARRSWGVDARDLPL
                     RAPGTDEAAWFLGWHRFRRAHGLPARVYATVSDSGARGATGAKPSYLDFDSPLSLAAFE
                     ALLRTDKARAVLREALPDEDGLHAASPRGRHVTELAVETLPAPTPTRTAP"
     gene            complement(18848..20455)
                     /locus_tag="B590_RS10920"
                     /old_locus_tag="B590_11035"
     CDS             complement(18848..20455)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643007.1"
                     /locus_tag="B590_RS10920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11035"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_023417532.1"
                     /sec_met_domain="PF00881 (E-value: 6.5e-10, bitscore: 37.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGYAYDYAAAIMRRGRVHMEPVDHVPNWADGPRKTKHYPDTDLLP
                     LPDSGYPADAALDQGLNPGPLDRPGHFDLATLSGMLRDSYGLTGRRLGVQANTDLDALP
                     HYPLANFSRGSASGGGLYPVSVYWVSGPSAPLPPGVHHYATRHHAMRRLLTGDATGEVR
                     AALEAAGPGAPGEGDATDQYLVLSIKYWQNAFKYNSFSFHAVSMDLGACVQTWRMWARA
                     RGLDVEPALWFDEERLARLLGVRTEEEGIFAVVPLRWQGATGAAAPPATPFAVRHRDVE
                     RSRTVLTFEAVTAMQAATAEGALDRPAPGALAPAAAHPAGPALPEAPLPAATPLTTDVR
                     TALRRRRSSFGRFDASRPLSAADLAALCRAATDGSYLGGDTGTGAGGVRLAGLYVFVNH
                     AEDLAPGAYAYDPGAGTLRLVKEGAPGPFLQKNYFLSNYNLEQAGAVLVPTVRTTAVLD
                     AVGDRGYRLVNATIGAVAQSVYTAAAALDVGCGVALGFDNISYIEELGLEATGEAPLLI
                     MMAGHERPAPADYRHELT"
     gene            complement(20509..22461)
                     /locus_tag="B590_RS10925"
                     /old_locus_tag="B590_11040"
     CDS             complement(20509..22461)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895330.1"
                     /locus_tag="B590_RS10925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11040"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_023417533.1"
                     /sec_met_domain="TIGR03604 (E-value: 5.1e-90, bitscore:
                     300.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 2e-75, bitscore: 253.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRADTLDQAAGAPGRADGDPVAAFAAGLHRALAAHSTPVPLDLAP
                     LGVHDAFREPLAAYEAGAVPVRIYGRQAVVGPFPGEREQPCARCLERRWQAVRSVTLRE
                     ALELGAGTRAAGENPYLTVFGADAVAGLIAARLGGRGPATGAFAAVHLVDLQTLRTRHY
                     PLVPDPECPRCSVVEEDTAEAATLTLGPAPKHRPGSFRVRDLATYELPLSPYANPLCGS
                     LGPSVVQDVSSGSTSATVGCFSMRSGDYLRETFWGGHADTFGQSLRIGVLEGLERYAGM
                     RSRAKKAEVRASLDQLVARGEQVVDPRVAGLYDEAFHAANPHVPPFTTGREIPWVWGYS
                     LRDERPVLVPEVLTYYHAPGLENRFVQESSNGCATGGCLEEAVYCGLMEVVERDAFLLA
                     WYGRAALPEIDPATSTSPATRHMVDRLAMYGYEARFFDTRITFPIPVVTGVAVRPDGGP
                     GRMCFGAGAGLDPEAAVAGALCEIATDAVNLPGRTRRDEARLRAMATDFHRVEALHDHP
                     LAYGIPEMGDHADFLLGAPGTPRPAKRSFAELYGDGSLPPVSDDLRDDLARCVGAVTGA
                     GFDVVVVDQTMPEQRALGLRTVSVLVPGLLPIDFGWTRQRALGMPRLRTALREAGLAGR
                     DLTDADLNPAPHPFP"
     gene            complement(22451..24673)
                     /locus_tag="B590_RS10930"
                     /old_locus_tag="B590_11045"
     CDS             complement(22451..24673)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895331.1"
                     /locus_tag="B590_RS10930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11045"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_023417534.1"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     5.9e-10, bitscore: 37.3, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 6.8e-17,
                     bitscore: 59.7, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADPTTEPAPATAPAADAFDALAATRPRVRRDVLFTQTPGGVLFH
                     NADGGFHLTGRTAYRFAALVLPHLTGRHRLDEVCAGFGPAQRAMAAELVRTLYARDFAR
                     DIPEADALRPAPEDAAGQRFAAQIAYIDHYTDAAPDRFARYRAARVAVLGTDETARWVA
                     LGLVRNGCGAVGLAAEFPDVTAEAAQLGDEGCPVSLGRLPDPSEGPGWAALDGYEVVVV
                     TGPGAAGLTHRLLTEGVPEGRTLLPAWAFGERLVMGPLTTGADTATATGGCWSCALLRL
                     GAGVDAGTAAALWSEVAGGARSVDAGAPGPLTGPVAAMCGNLLAYEVFRLTSGVQPAET
                     RGQVLIQDLSSLDVLAEPVPPHPRCRHCAPSGVPVTSPGTPEVPRTPSVAGAEEAQEVV
                     DALNATASALVRPHTGVFTRFDDDDLTQTPLKVSRVELPLPDGTVRAVTAADIHHLAGA
                     RTRALHRAAVLYVDHTVPAPVAGEGHGAPVDPAALATFGGTDATPAAALTPALSLRTGE
                     PHRVPVSAARPFGPHNRLRTHLAATAGAGAGSSAAEAAGAALLAALAHAAVLHAVRGRG
                     AVLLAQDTTGDAELEFLHKTAAALDLGVELLDLTGDGPAPVVLAREPGGRWAAAADLTR
                     REAARAALRDLLGDAQLAAETGQEPDSGDPFVTDLAPAALTLAGEPGGPLDAATTFPEI
                     LARLGESGRDALYLDTTPADLATGRLATARVLLTVAAPAEGGTDAR"
     aSDomain        complement(24353..24604)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B590_RS10930_Heterocycloanthracin_C_R
                     RE.1"
                     /evalue="2.70E-12"
                     /identifier="RREFam011.1"
                     /label="B590_RS10930"
                     /locus_tag="B590_RS10930"
                     /protein_end="107"
                     /protein_start="23"
                     /score="37.3"
                     /tool="antismash"
                     /translation="ATRPRVRRDVLFTQTPGGVLFHNADGGFHLTGRTAYRFAALVLPH
                     LTGRHRLDEVCAGFGPAQRAMAAELVRTLYARDFARDIP"
     aSDomain        complement(24368..24601)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B590_RS10930_Thiopeptide_F_RRE.1"
                     /evalue="3.20E-19"
                     /identifier="RREFam004.1"
                     /label="B590_RS10930"
                     /locus_tag="B590_RS10930"
                     /protein_end="102"
                     /protein_start="24"
                     /score="59.7"
                     /tool="antismash"
                     /translation="TRPRVRRDVLFTQTPGGVLFHNADGGFHLTGRTAYRFAALVLPHL
                     TGRHRLDEVCAGFGPAQRAMAAELVRTLYARDF"
     gene            complement(24680..26566)
                     /locus_tag="B590_RS10935"
                     /old_locus_tag="B590_11050"
     CDS             complement(24680..26566)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018471569.1"
                     /locus_tag="B590_RS10935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11050"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_023417535.1"
                     /transl_table=11
                     /translation="MRFQLLGPLSLHDGPESVVLQPAKPTVLLTALLLHANSVVSADYL
                     QRAIWGEEQPATAKAALQTCVLRLRRLFTKHGVTETPIEAVPGGYRITAGPHTLDLIGF
                     RERVRRAAALTHDPQAELASLRDALALWQGPLLANVRSDLLHRDEVPRLAEERLRAVER
                     LCGLHLRLGRCGEALGDLWEVTRAHPGHERFHEQLVEALYRTGRQAEALAEYRRVKEYL
                     LQELGVDPGAALQRLELAILRGDTLAAGPAGEEDGRPAALPDAPAAPGSEEPGPVAPLT
                     PVPDFTGRAPEVAALTAHLTADTAHRPGGPLTVVLSGAPGIGKSALARHVATQLADRFP
                     GGRLLIRLTGPDGRPHDPETVAGQLTRALAARPPGSATLLILDDAAGADQVRPLLAACT
                     GGAVVVTSRRGLAGLVATHGGRVVRLGPFRPAESHTLLRSVLGAERVDAEPDEARRIAE
                     GCGHHPLALRIMTARLLTRPGLGLADSARWLGPDQAGRLALTDAPGLSVPEVLGEALAR
                     LEPPLADAFLRVAALGPACGADEAAPALGLGEAETEQLLDRLADAGFLEEGPPGPYRTL
                     PLLRAWARGRGRAPAASGPTPQAPDPARTGRCPHCRTARAHRPELPRPAEKV"
     gene            complement(26575..26808)
                     /locus_tag="B590_RS10940"
                     /old_locus_tag="B590_11055"
     CDS             complement(26575..26808)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643014.1"
                     /locus_tag="B590_RS10940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11055"
                     /product="hypothetical protein"
                     /protein_id="WP_023417536.1"
                     /transl_table=11
                     /translation="MSGNRNAHCPHPVSSVRPRRARAAAALAGAVAVLALGAGQAVAQA
                     PDAAPVPVSPLVNGWDGVRADPGYGKLVNGWD"
     gene            27257..28849
                     /locus_tag="B590_RS10945"
                     /old_locus_tag="B590_11060"
     CDS             27257..28849
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643016.1"
                     /locus_tag="B590_RS10945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11060"
                     /product="MFS transporter"
                     /protein_id="WP_023417537.1"
                     /transl_table=11
                     /translation="MNEGPASGTPDLPRPRGPHPGESGPKPPAPAPDARRGAVVAALML
                     SMALAALDGTIVSTAVPQIVGDLGGFSSFSWLFAGYLLAVTVTLPVYGKLSDTLGRKPV
                     LIMGSVLFLLGSLLCAVAWDMTSLIAFRVVQGLGGGALQGTVQTLAADLYPLKERPKIQ
                     ARLSTVWALSAVAGPGLGGLLATYADWRWIFLINLPVGAVALWLIIRHLHEPVRERTGP
                     RPRIDWAGALSIFCCGAVLLTALVQGGVAWGWLSPPSLALFGAGAVLAAVTALVERRAA
                     DPVLPGWVWRRRTIAAVNLALGCLGLLMVAPTVFLPTYAQSVLGLAPVAAGFVLSVMTL
                     SWPLAAALSQHVYRRIGFRDTALVGIGGATLVLLAFPLLPYPGSGWQPALLMLALGAAL
                     GLFQLPLIVGVQSTVGWEERGTTTASVLFCRQIGQTLGAALFGAVANGVLTARLGDTSG
                     DLDAVARALDEPGAMDPSTADTLRRAVASAVETVHLGAACAGAAAFVLLLSLAPRRFPV
                     RGEHTGPASAERA"
     gene            complement(28869..29420)
                     /locus_tag="B590_RS10950"
                     /old_locus_tag="B590_11065"
     CDS             complement(28869..29420)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895335.1"
                     /locus_tag="B590_RS10950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11065"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_037970318.1"
                     /transl_table=11
                     /translation="MWRVLAARGFGGLTLRAVAAEMGATTGLVTHYFPSKRALVRHALE
                     VLDGRSAGRPRPAEERVGEASGLVRLRAVLLDVLPLDGPGAANNRIWVGSWDVALADPE
                     LAAEHAARYRRARERMAGYVAEAQRSGELPAGPEAGDVAAAAQSFVLGLVVQALFAPQE
                     FPPVRQVALVDGYLAGLAAG"
     misc_feature    29493..29506
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.71"
                     /tool="antismash"
     gene            29539..30102
                     /locus_tag="B590_RS10955"
                     /old_locus_tag="B590_11070"
     CDS             29539..30102
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018471565.1"
                     /locus_tag="B590_RS10955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11070"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_023417539.1"
                     /transl_table=11
                     /translation="MYAIPLAPGAELRPLEPWQAPEFLAHIDRARAHTDPWIPWATYST
                     DLDSARATLQSYADKQAADRGRVFGIWREGTLVGGVMFVRFDAAGGTCEIGVWSEPAGE
                     GLGLITAAARHLLAHAFTTRGLNRAEWRTTPRNTRSRAAAQRLGMTLDGTLREHSSYRG
                     ERLDIEVWSLLAREWERKERADRA"
     gene            complement(30139..30906)
                     /locus_tag="B590_RS10960"
                     /old_locus_tag="B590_11075"
     CDS             complement(30139..30906)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643026.1"
                     /locus_tag="B590_RS10960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11075"
                     /product="NPP1 family protein"
                     /protein_id="WP_023417540.1"
                     /transl_table=11
                     /translation="MNTGSRIRRAAFTLAAATGLVVAFAGSAHADPPAALPASADALEQ
                     TYQPAYDYDTDGCYATPAIGPDGTLNGGLNPSGALNGQCRDAWDLDNTNTYSRAKCDGD
                     WCAVLYGSYFEKDQAVAGSGLGGHRHDWEHVVVWVNGGEARYVATSAHGGFKVHDRDAI
                     RWDGSHPKIVYHKDGASTHCFRAATANDEPPENHQGTWQYPALVGWEGYPAGLRDRLSQ
                     HDWGSANFGLKDAGFGSHLEKAKPSGIDFDPYA"
     gene            31189..31443
                     /locus_tag="B590_RS32465"
                     /old_locus_tag="B590_11080"
     CDS             31189..31443
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B590_RS32465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B590_11080"
                     /product="hypothetical protein"
                     /protein_id="WP_023417541.1"
                     /transl_table=11
                     /translation="MRCRTAATSAVAALTLLLTGCGADSPYEAGYAHGQERRGTLGGDL
                     FGQIFHCATWAKEQYEEKADRNAFKRGCQHGINDLPSRP"
     gene            31506..32357
                     /locus_tag="B590_RS10970"
                     /old_locus_tag="B590_11085"
     CDS             31506..32357
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-267). E-value:
                     1.8e-26. Score: 85.2. Matches aSDomain:
                     nrpspksdomains_B590_RS10970_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895340.1"
                     /locus_tag="B590_RS10970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11085"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_023417542.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-22, bitscore: 79.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5e-17, bitscore:
                     61.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTFTAPDGTPLACHAAGDGPPLVCLPGGPFHPAAYLGDLGGLTA
                     HRRLLGLDLRGTGASGVPADPASYRCDRRVADVEALRRHLGVDRVDLLGHSAGANLAVR
                     YAERHPDHVDRLILATPSTFAVGLDVPGPVRAATARLREGEPWFPEAYTALEEVAAGRA
                     TPASWEAMAPFMYARWDDEARAHRALGTPWRGTEAAATYGSEGAFDPPATRAALAAFTR
                     PVLLVAGELDLNSPPEVVTSYAARFPDARLTVLPGVSHFPWVDNPPAFAAAVSDFLGRR
                     TS"
     aSDomain        31566..32306
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B590_RS10970_Abhydrolase_1.1"
                     /evalue="1.80E-26"
                     /label="B590_RS10970_Abhydrolase_1.1"
                     /locus_tag="B590_RS10970"
                     /protein_end="267"
                     /protein_start="20"
                     /score="85.2"
                     /tool="antismash"
                     /translation="PPLVCLPGGPFHPAAYLGDLGGLTAHRRLLGLDLRGTGASGVPAD
                     PASYRCDRRVADVEALRRHLGVDRVDLLGHSAGANLAVRYAERHPDHVDRLILATPSTF
                     AVGLDVPGPVRAATARLREGEPWFPEAYTALEEVAAGRATPASWEAMAPFMYARWDDEA
                     RAHRALGTPWRGTEAAATYGSEGAFDPPATRAALAAFTRPVLLVAGELDLNSPPEVVTS
                     YAARFPDARLTVLPGVSHFPWVDNP"
     CDS_motif       31584..31643
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B590_RS10970_0001"
                     /evalue="2.10E+01"
                     /label="NRPS-te1"
                     /locus_tag="B590_RS10970"
                     /protein_end="46"
                     /protein_start="26"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="PGGPFHPAAYLGDLGGLTAH"
     CDS_motif       31776..31820
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B590_RS10970_0002"
                     /evalue="7.90E-04"
                     /label="NRPS-te1"
                     /locus_tag="B590_RS10970"
                     /protein_end="105"
                     /protein_start="90"
                     /score="12.0"
                     /tool="antismash"
                     /translation="DLLGHSAGANLAVRY"
     gene            complement(32460..33449)
                     /locus_tag="B590_RS10975"
                     /old_locus_tag="B590_11090"
     CDS             complement(32460..33449)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643031.1"
                     /locus_tag="B590_RS10975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11090"
                     /product="hypothetical protein"
                     /protein_id="WP_023417543.1"
                     /transl_table=11
                     /translation="MSSTPASPHGFATIRGRGYRPAQADQYVAALERERDEAHAEAERL
                     TALAEGLGAEAAVLAETVATLSEPTYDNLGERAQRLYALVQEQSEALDAAGRAEAAALT
                     AAAEQAAADLREAARRYAAETRAEAERQADDRLAAARAEAHQLLTDARAEAQAERAAAE
                     AALDEARQLTARTLAGQERDLAAREAEAERELAERDTVARGHEGALDDHGDAVLAEARR
                     HHAEAEEAVRRTDQEAQTQAAELLQQAQATADRVAAEAERLVRDHEEQREALRARMEHI
                     RTALAALTGRGVVGVPAAPEAEAAPEARTALPGARRKQPGGGAEPDVA"
     gene            complement(33588..34532)
                     /locus_tag="B590_RS10980"
                     /old_locus_tag="B590_11095"
     CDS             complement(33588..34532)
                     /GO_process="GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507264.1"
                     /locus_tag="B590_RS10980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_11095"
                     /product="LCP family protein"
                     /protein_id="WP_023417544.1"
                     /transl_table=11
                     /translation="MVLWTVVALVVVVAAAGTAVYFWADGRVRTTDAFGEYAGRPEAGR
                     GTDWLLIGSDSRATLTPEQRRELHVGSDEVRNTDTLMIVHQGDHGTTMVSLPRDSYVAI
                     PGHGQGKINSAFALGGPKLLTRTVEQATGLRLDHFAEVDFLGFVDVVDALGGVRICVPA
                     GGLRDRKSGADFAAGCREMDGVQALSYVRARYSDPEGDLGRVRRQRQLVSAVADKASSP
                     AVALNPWRAGPFLSASLDAVTVDRRADVSDLFRLGRGLRGAAGDEERALTVPLRSEGEV
                     PGAGDVVVWDRRRAGELFVALREDRPIPTSDLK"
ORIGIN
        1 ggtcacccag cgtcgctcac catgtgcgaa gagcgattcc ggtctgggtt ccgtgtccaa
       61 ggaggacggg cttgagtacg acagcttccg cagcgagggt ccgcgtatgg tcaggagagt
      121 tccggccgga ccgcagggcg gtgcgagagg cgagggcgac cgcgagacgg ctgctcccct
      181 ggctcggcta ccggggagag ctggatgctc ccgtactgat cgtctcggag ctggtcacca
      241 acgccgtcga gcacggttct tccctggagg acaccgcgct tctgctgcgg ctgagcgtcc
      301 atccgtgcgg cggcctgtcc gtcgaggtga ctgacggagg aaccacccct cccgggccac
      361 ccgcaccgcc tccctgccca gaagccgaaa gcgggcgcgg tctgttcctc gtccacgcgc
      421 tcggagctcg tacgacctgg gaacaggccg caacgggcaa gaccatgcgc gccttcctcc
      481 ctctgggcgg gacggtgccc cgatgaccgc ggcaggtgcc tcgcaccggt ggccagaccc
      541 ggatctgctc tgcatggagg cgctgcgcgt gctgtcggac gccgccgacg ccgccctggc
      601 agggcagggc ctctccgcgc gtcaggccag tcagctggct gcctggctgc gggccttgtg
      661 cgagagctac ggcgaggcga cccatccggc cgtggtggca gccgtacgcg ccgcgaacag
      721 ggctctcggc cccggagttt cccccgtcct caccctggcc acccacgccc gcggactcct
      781 ggacctgact ttccggctac gtgccgaggg gcggcccgta caccccggcg cgtgaccgga
      841 gtgaggaccg ccccaagccc ctacgacccc acaatcgacg tcaggaactc ccccacccag
      901 gacagcagct cccgccccac cacaggcttc cccccgatct tcccggtcgt ggggcgcggg
      961 accaggatct ggtgggtgtt ggccttgatg accgtgcggg ggtagaggcg gttgaggcgg
     1021 agttgctggg attcgcggag ttcgacgggg ccgaagcgga cgttgttgcc ctggaggacg
     1081 atctccgcga cgccgcagga gcgggcgagc atgcggaggc cggcgacgag gaggaggttc
     1141 tcgacgggct cggggagttt gccgtagcgg tcggtgagtt cctcgcggac ggcgcggacg
     1201 tcgtcctcgg tggtggcgga ggcgatggca cggtacgcct ggaggcgcag gcgctcgccg
     1261 ggggcgtagt cgtgcgggac gtgggcgtcg acggggagtt cgatcttgac ctcgggggcc
     1321 ggttcctcct cgacgccgcc gtcgagggcg gcgcggtagt cggcgacggc ctcgccgacc
     1381 atgcggacgt acaggtcgaa accgacgccc gcgatgtggc cggactgttc gccgccgagg
     1441 aggttgccgg cgccgcggat ctccaggtcc ttcatggcga cgtacatgcc ggcgcccatc
     1501 tcggtgtgct gggcgatggt ggcgaggcgc tcgtgggcgg tctcggtcag gggcttctcg
     1561 ggcgggtaga ggaagtaggc gtacccgcgt tcgcggcccc ggcctacgcg gccgcggagc
     1621 tggtggagct gggagaggcc gaagttgtcg ccgcgctcga cgatgagggt gttggcgttg
     1681 gagatgtcga tgccggactc gacgatcgtg gtggagacca ggacgtcgaa cttcttctcc
     1741 cagaagtcca cgacgacctg ttcgagggcc tgttcggaca tcttgccgtg ggcggtggcg
     1801 atccgcgcct cggggacgat ctcgcgcagc cgggctgcgg ccctgtcgat ggactcgacg
     1861 cggttgtgga tgtagaagac ctggccctcg cggaggagtt cgcggcggat ggcggcgccg
     1921 atctgcttcg ggtcgtaggg gccgacgaag gtgaggaccg ggtggcgctc ctcgggcggg
     1981 gtggtgatcg tcgacatctc gcggatgccg gtgaccgcca tctccagggt gcgcggaatg
     2041 ggggtggcgg acatggtgag gacgtcgacg ttggcgcgga gcttcttcag ctgctccttg
     2101 tgctcgacgc cgaaccgctg ctcctcgtcg acgatgacca ggccgaggtc cttgaacctg
     2161 gtctcggagg agaagaggcg gtgggtgccg atgacgatgt cgacggagcc gtcccgcagc
     2221 ccttccaggg tggccttggc ctcggcgtcg gactggaagc gggagagggc gcggacgttc
     2281 accgggaact gcgcgtaccg ctcggagaag gtgccgaagt gctgctgcac caggagggtg
     2341 gtggggacga ggacggcgac ctgcttgccg tcctggacgg ccttgaaggc ggcgcggacc
     2401 gcgatctcgg tcttgccgta accgacgtcg ccgcagatca ggcggtccat cgggaccgtc
     2461 ttctccatgt cgtccttgac ctcggcgatg gtggagagct ggtcgggcgt ctccatgtac
     2521 gggaaggcgt cctccagttc gcgctgccag ggggtgtcct ggccgaaggc gtgcccgggg
     2581 gcggccatcc gggccgagta gagcttgatg aggtcggcgg cgatctcctt gacggccttc
     2641 ttggcgcgcg ccttggtctt ggtccagtcg gcgccgccga gccggtgcag ggtgggggcc
     2701 tcgccgccga cgtacttggt gacctgttcg agctggtcgg tggggatgta gaggcggtcg
     2761 ccgggctggc cgcgcttggc gggggcgtac tcgacgagga ggtactcgcg ggtggcgccc
     2821 tggacggtgc gctggaccat ctcgatgtag cggcccacgc cgtgctgctc gtggacgatg
     2881 tagtcgcccg gctccagggt gagcgggtcg atggtcttgc ggcgccgggt gggcatccgc
     2941 tggccgtcct tgccggccgc cttctggccg gtgaggtcgg tctcggtgag gacggcgagc
     3001 ttgaggcgct cgtcggtgaa gccgtggtcg atggcgccgc aggcgacgtg gaccacggag
     3061 gggctgatct ccccgaggtc cccgtcgagc cgggccggga cgccctcgga gcccagcacc
     3121 tcgacggtac gggcggcggg gccgtgcgcc tcggtgacga agacggtccg ccagccctcg
     3181 ccgagccacc gcttggtgtc ggccagggcg cgggcggtgt cgccccggta cgtctccggg
     3241 gcgcgcatcc ccagctgcca ggtgtcgccg tcgtacgtct cctcgtcagc ggcgaacggc
     3301 gagacggacc accacatcat gcccagttcg cgggcgcgct cgcggacgtc ggcgatgccc
     3361 cacagggagg ccgcgccgac gtcgacgggg gcctcgccgc cctcggcgga ggcggcccag
     3421 gacgcctgga ggaattcgag gctggtggcg accaggtcgg cggcgcgggt gcggacccgc
     3481 tcggggtcgc agaccagggc catggcgccc tccggcagca cgtcgaggag gagttccatc
     3541 tcgtcgacga ggacgggagc cagggactcc atgccctcga cggcgacgcc ctcggcgatc
     3601 ttcccgagga gttcgcccag ctcggggtgg tccacggcga gggcggcggc gcgctcgcgg
     3661 acctggtcgg tgaggaggag ttcgcggcag ggaggggccc acaggccgtg ctcggcgatc
     3721 tccagggagc gctggtcggc gaccttgaag tagcggatct cctcgacctc gtcgccccag
     3781 aactcgatgc ggaccgggta gtcctcggtc ggcgggaaga cgtcgaggat gccgccgcgc
     3841 acggcgaact cgccgcgctt ctcgaccagc tccacccggg agtacgcggc ggcggccagc
     3901 gcccgcacca cctcctccag gtcggtggtc tgcccggcct tcagcgccac cggctccagg
     3961 tcgccgagcc ccttgacctg cggctggagg acggagcgca cggaggcgac gacgacggag
     4021 accgggccgg tctcggggtc gtcggcgtcc gggtgggcga ggcggcgcag cacggcgagg
     4081 cggcggccga cggtgtcgga gcggggcgag agccgctcgt gcggcagcgt ctcccaggag
     4141 gggtactcca cgacgccgtc gggcgggagc agggtgcgca gggcggccgc caggtcctcg
     4201 gcctcgcggc cggtggcggt gacggcgagc acggtacggc cggtctcgcg ggcgagggcg
     4261 gcgacggtga aggggcgggc ggcgggcggg cccaccaggt cggccgcgag gaggtgcccg
     4321 tccccggccg ccttcagcgc ctgggtcagc gccgggtcct cggtcaccgc gtcgagcagt
     4381 ccgtgcaggc tcatgaaagg aagtccgtcc tcgttcgtgc tcgtcgtggt cgtcgtccac
     4441 cgcgtgcccg gcgctgccgg gcgccgagac gcccgcgcgg ggcggagtcg tcacgccgcc
     4501 ggggaacacg cgagtgcccg acacgtccaa cgggccgggg ggctccagcg tacgacgtgc
     4561 ggccgacgga cgcgtccggc acggtacgtc gcgtcccgct cgcgctgcgt tgcccggccg
     4621 cgtgccgtac ggacggaagg cgtccggggt tcacgcggaa ccgggcacgg ttggctcact
     4681 cttcgcacac aattcgcacc ggccccatcc cggcgcggcg cgcgaacgct tactctgtgc
     4741 cgaaaaaacc tcgaccgtcg cggcacgtgc ccggacaatc tccggacggt gccgtcggcc
     4801 catgacgcag ccgggggcag agcgtgggtg acaacgagat ggccgtcttc gggctctccg
     4861 cgaccgagga ggagctgtac cggcatttcc tgcgcaatcc ggggacctgc gccgacgatg
     4921 tgcacctgct gctgcgcacc gccgaccggg ccggcaagga cgcggcccgg gcgctggacc
     4981 gcctccgcga gctgggcctg ctgctgcccg ccgggccgga cggccgggtg gtcccggccg
     5041 acccggaaca ggccgtatcg cacctgaccg accggcggct gcacgagctg caccaggatc
     5101 tgcggcgggt cacccggtcc cggcacgtgg tggacgggct gcgggccgag cagggggcgc
     5161 gcaccgccgc cccgcagggc atcgagcaga tcgaggggct ggcggcgatc cgcggccgca
     5221 tcgaggacct ggccttcttc gcccgcgagg agatcctctc cgtggagccc tacacgcggc
     5281 tctccccgga gaacatcacc cgctcccgcc cgctggacct gcgctgcctg gcccgcgggg
     5341 tcaccatccg caacgtggtc cgccactcgg ctctcgccga cccgccgacc gccgcctacc
     5401 tgcgggagct ggccgccgcc ggcgcccaca tccgggtcgc ggacgagggc gaggcgggcg
     5461 agcgcctcct cgtctacgac cgccggtccg tcctggtccc cctcgacccc cgcgacaccg
     5521 cgcgcggcgc cctgctggcc cacaagagcg gcctggtcgc caacatcatc gccctcttcg
     5581 agaagatctg ggcccaggcc gcccccctgg acgacgccgc gggacagcac ggcgagagcc
     5641 ccctgagcga gatggaacgc cgggtgctcc tggcgatgtg cacggtcggc aaggacgagg
     5701 cgggcgcccg cgaactgggc gtctcggtgc gtacctaccg gcggcacgtc gccgacctga
     5761 tgcaactgct cggggcggcg agccgggcac aggcggcgtt gctggcgcgg gagcgggggt
     5821 gggtctgagt caggggcgcg ggtcgagcgg ggtgaggacg ccgagccggt cctcgatcgc
     5881 ctgggccgcc tccagacaca ggtcctcccg gaaggcgcgc ccgacgacct gcaccccgct
     5941 cgggagcccg tccaccaggc ccgtggggac ggccacgccg ggtacgccgg cgaagctggt
     6001 cgcggtgcac agccgcatcc cggtgccgac ccgctcgcgg cccgcccggt tccgggactc
     6061 cagccccggt tcgaccggcg gctcggtgaa gacggggccg agcagcagcg ggtacgcgtc
     6121 gaggaactcg gcccagcagc ggcggatgcc gagccaggcg cccgtcagcg ccgtcagttc
     6181 cccggcggtc gcgggcgggg tctcttccat cgcctcggcg atgtagcggt cgccgccggg
     6241 gccgagcagg gtgcgcacca ccggccagga gggcgcgaac tcggtgatcg tgatgcggcc
     6301 gtacacctcc agggcctcgt cgagacgggg cacgtccggc acctcgcaga gctcgtaccc
     6361 ggcgtcgcgg agcgcgtcgg ccgcccgtgc gacggcctgg cggaccgagg ggtggacgcc
     6421 gtggccgccg gggtcggcca ccaccgcgac cttgagcggg ccggggaggc gttccccgta
     6481 cgcggggacc ggtacggcgc gcgggtcccg ggggtcggtg ccggccagca cctcgtaggc
     6541 gagccggagg tcggccacgc tgcgggccag cgggccgtcg gtgaccagga gctgggaggc
     6601 gaggccgggg tcgtccgggc cgatgacgcg gtggtcggcg gggaagcggc cggtggacgg
     6661 cttgagtccg gcgacgccgc agaactgcgc cgggatgcgc accgacccgc cggagtcgtt
     6721 gccgaggccg agcggggcca tgccggtggc gacggccacg gcgtcaccgc cgctggagcc
     6781 accgggggtg cgggcggggt cccacgggtt gaccgtgtcg ccgaacagct cgctgcgggt
     6841 gtgcatgccc gccaggatca tggtggggat gttgccgtgc ccgacgggga tcgccccggc
     6901 ggcccgcagc cgggccacgg gcagcgcgtc ggcgcgggcc accaggtccc ggaagcgttc
     6961 ggcgccgaag gtggtgggga cgccttcgac cggggtgctc tccttcacgg tgaaggccac
     7021 tccggccagc gggcccagct cctcgcccgc cgcccgcctg cggtccagcc gcgccgcctc
     7081 ctcgcgggcg cggtccgccc agagctgggt caccgcgttc acccgcgggt tgaccgcctc
     7141 gatgcgggcc aggtggctgt cggtcagttc ggcggccgag acctgcccgc cgcgcacggc
     7201 cgcggcctgg gccgtggccg tcatcctcca cagggcgtcg tcctgcatgg ttctccgttc
     7261 cggggcgtgt tgcgtcgttc cgatgcgctc gcatcggaac gacacggtaa cccctgaacc
     7321 gatacgcgcg catcgaataa gctgcgggcg agtggagtgc ggcacgacga gagggacggg
     7381 catgcccaag caggtggatc acgcggaacg gcgccgcctc atcgccgggg ccgtctgccg
     7441 gctcgccgac gagcgcgggc tggaaggggt gaccctgcgc gacgtggcgg cccgcgccga
     7501 ggtgtcgatg ggggcggtgc agcggtgctt ccgcaccaag gaggagatgc tcgccttcac
     7561 gctcggccag atcggcgagc gggtcaccgg gcgcgtacgg gcccgcctcg tcgagagccc
     7621 ggcccagtcg gcccgcaccg cgctgggcca cgccgccgag gagaccgccc tgctgcgcgg
     7681 ggaggaccgg gccgaggccc gggtctggct cgccttcgtc gcgcaggccg ccgtcagccc
     7741 ggcgctggcg cggaccctgc gggccgacta cgcccggctc caggaggcgt tcaccgggct
     7801 ggtccgggag gccctggcgg acctcgggca ccccgcgccg cccgatgcgc gccgcgccgc
     7861 ccgcaccctg ctggccctcg cggacggcct caccacgcac gtcctcgtcg gccacctcac
     7921 cccggaggag gcgtacgacg tgctccacgc gcacctggcc gggctctggg aggcgccgcc
     7981 cggctcagcg gactgacgcc ccgcgcccgg ccatccccca cccgcacagc gccgggtcgg
     8041 ccagggccct ggccagggcc ggccctggct cggcgggcgc ggggcggacc cgcaggcgga
     8101 gctggtcggt gcccgcgtcc gggtggcagc accagtcggc ggggaggagg gccaggaggc
     8161 ggatgacggt gatctggccg ggtggggcgg cggggtcggc gcggtggagg gtgacgtcga
     8221 ggtgggcggg gagccggggg gtcatggggc gacctccggg tggggcggga ccgggaccgg
     8281 gaccgctccc acggtgggcg ggccggccgc gaggaggtgg cgggcggcgg cggtgagcgc
     8341 ggtgacgccg gtgggcaggg cctggcggag gtcgggggcg aagtcggggg cgtggttggc
     8401 ggggacggtg cggccctccg cggcggcggc ccgccaggtg gcggcggggg tggtgccgag
     8461 catccagtag gcgagcggga cgtgagtgcc gtcggggagg gcggtgaggt gggtgaggtc
     8521 ctcggtggcc ggggaggggg cggcggccag gacgcggccc gcgccgaggt gggccgtgtg
     8581 gacggtgcgc agggcggcgg tgagggcggg gtccggggtg aggacgggcg agcgggcggt
     8641 gagggccagt tcgggcgggc ggggtgcggc ggcggcctcg ctctcggcgt ccaggacgcg
     8701 gcgtaccgcc tcgtggagcc ggtcgagggc tggttcggtg aaggcgcgca ggcccagcga
     8761 gagggtggcc cggtcgggga tgacgttggc gcgggtcccg gcgtgcaggg tgccgacggt
     8821 gaggacggcg ccttcggcgg gggcggtctc ccgggcggtg agggtgtgca gcctcaggac
     8881 ggcggaggcg gccatcagga gcgggtcggc ggcgaggtgc ggggtggcgg cgtggccgcc
     8941 gcggccgtgc aggacggcgt ccagggtgcg gctgccggcc atcagggggc cgccggcggc
     9001 gtgggcgacg gtgccggcgg ggagcggggc ggcgtgctgg gcgaggatcg cgtcggggcg
     9061 gccgaaccgg tcgtacagcc cgtcctcggc cagcgcgcgg gcgccggtca gggtctcctc
     9121 ggcggactgg ccgaggagaa gcaggcgccc ccgccagccg gcgcgggtgg cggcgaggcg
     9181 ggcggcggcg ccgagggcgg cggcggcgtg caggtcgtgg ccgcaggcgt gcatggcgcc
     9241 ggggacggtg gaggcgtagg gcaggccggt ggcctcggtg acggggaggg cgtcgagttc
     9301 ggtgcggatc aggacggtgg ggccgggtcc gttgcgcagc tcggcgagga aggagggagt
     9361 accggcgagg ccgcggtgga cggtgaggcc gagggcggtg aggcggtcgg cgagcaaggc
     9421 ggcggtggcg tgttcggcgc cggagagttc gggggcgcgg tgcagggcga ggtacagctc
     9481 gacggcggcc ttcacctcgg cgcggggcgg ctgggtctcg ggggcggcca cgggcgtcac
     9541 ctctccgtcc tcaggtacgg ggccgtccgg gcagcgtgcg gcgcggccgt gtcaggggcg
     9601 tctcgttccg ctgtcagggc actgtcaacc ggtgacagcg gggtggtggc ggatctgaca
     9661 gcgggtgggg ctgggatggg ttcagcaggt gagttccgcc ggagcggccg gtggacccct
     9721 gggaccgcag ggagtacgcg atgaccccca agaccgagct ggccaccctc gccgacgaga
     9781 tcctggagct ggagtcggag accttcgaga tctcggacta ctcggacgcg gccgaggtcg
     9841 tgctcgccgg ttcgacgtcc tgctcctcga cgtcgacctg ctccagcacc accagcacca
     9901 cctcctgctc ggcctgatcc ggccgatcgc gcgtacggcc cctgtcccgg cggcgtccac
     9961 cgccgggaca ggggccctcg tgcgtcgcgg gcccggacgg tcacgggaag gggtgcgggg
    10021 cgaggtggac ggcgccggcg gggaggtcgt cggcgcggcg tccggcggtg cgcagcccgg
    10081 tgcgcaggcg gtccatggtc agggcgcgct gccgggtcca gccgaagtcg atggggagca
    10141 ggccggggac ggcggtggcg acggtactga gtcccgcgcg ggcctgttcg ggggtggtct
    10201 ggtcgacggc gatcacgtcg tggcccgcgt cggcgagggc gccggtgagc agggccaggt
    10261 cgtcgcggag gtcgccggtg cggggccgga cggcgtccca gtcggcgaag gcctcggcga
    10321 gcgggaggcg gtccaggggg tcgaggaagg gcgcggcgtg gtgcgccatc ccgggcaggc
    10381 cgtagagctg ggcgtggtcc ttgagttccc gtacgagggt gaagtcggct gccatggcgg
    10441 tgagttcggc gcgtcgttcg gtgacctggt agggcaggtg cgggatgtag gtgaggacct
    10501 cggagagggc ggaggcgacg gtctccgcgg ggtcgaaccc ggcggcggcg gcgaaggcga
    10561 gggtgccggg gccgccgtcg cggcgtacgg cgagggcggt gacgacgggg acgggcgggc
    10621 ccatccgggt gtcgtagacg tggatgtcgt agccgtgcag ggcggcccgg ccggtcatgg
    10681 cgcggacctc ggggtcggtg agggtggcga ggtcgatctc ggtgagccgg gcgcggccgt
    10741 accaggcgag caggaacgcg tcacgttcca cgcgttcgag aaggccgaaa aggatcgcct
    10801 cgacgaggcc ggagccggtg gcgcagccgt tggagcactc gaagacgaag ttgtcggcgt
    10861 ccacgcccgc gctgtagtgg gcgagccggg cgggaacgag gacgggccgc tcgtcgcgca
    10921 gcgagtggcc ccagacccag gggatctcgc ggtccgggtc gaaggggctg accagggggt
    10981 cgttcgcgta cgtctcgggg gcgtagaccc cgcaggtgcg cgggtcgagg gcgtcggagg
    11041 cgagctggtg gtagctgccg aggacggggg tggtgccgcg ccggcggtgg gtgccggcgt
    11101 accgctccag gccctccagg aaggcgagcc ggcggctggt ggcggtgcgg ttggcctggc
    11161 cggaccaggt gacgtcggtg agtccggcgt agccgcgcac gaagtgggtg ccggcgaccg
    11221 gggcggtggt ggtggaggcc gggttgatcc aggtgtcgga gccgagggcg ccgcagaccg
    11281 ggttggcgag ggcggcgacg ggcagggcgt aggcgccgag ggagcgtacg cggtaggtgg
    11341 ccgggtcggg cttgggtgcc ggctccaggg tgaggcgagc ccgctcggcg gtgtccgggc
    11401 gcggggtgac gcaggccggg cagagcgggt cgggcagcag cgggaaggtg gcggtggcga
    11461 gggtgaccag gtcggtgcgg gtgacccggg gcagggtccg gtctgcgggc tcctcggcct
    11521 ccggagcggt ccggcccggc cggtgcaccg cccggtacgc ggcccagacg gcttccacgg
    11581 cccagtcggt gaccagcggc cagccggtgg cgccgtacgg gacgtgccgc cgctccagcg
    11641 cctcccgttc ggtgcggccc cgcagccgct gccaccgcat ggccaggcac tggccgcagg
    11701 ccccggcggt ctcggcgtcg gcgccctcgg gcagccaggg cccggtgagg acggcgcgcg
    11761 aggtgaggtg gacggtggcg gaccgacgcg cggcggcgta cgggtccggg gcgccggtgc
    11821 cgagggtgtc ggcggcgccg agcgggacca cggacggggc cgggagcagg gcgcgttcgg
    11881 cctcggggag ggcggcgtgg cgggcggtca gagcggcctg gagctggtcg cgggcggcgt
    11941 ccagggggcg gggtgcggca ggtggcgaga gggcgggcgg ggtcgtggtg ggcgcggggg
    12001 tggcgggcat ggcgggctcc tgacgggccg gggcggggag gaacacgggg ccggggcggg
    12061 ggcgcctgtg ctccccgccc ggaccgggag gaccggtgcc tgcgcggcgg tcaggtgcgg
    12121 tcggaccagc ggaaggtctt gagggcgacg gccgtgaaga cgacggcgaa gcccgcgagg
    12181 acggcgcagg agaccaggat gtcgccggtg gtgccggagc cggtgaggga ggccgagaca
    12241 ccgtcgttga ggtaacgcag cggcaggaca cgggagacgg cctgcatcca gccgggcatg
    12301 gcgtcgagcg ggaagaagga gccggagagg aaggccatcg gcagcatcac gcagttggcg
    12361 acggcggcga ccgcctccgg ggtgcgggtg aaggagccga cgatgacgcc gagggcgagg
    12421 aaggcggtga cgccgacgac cagcatgagg aaggcgtacg gccagccgga ggagagttcc
    12481 aggccgaacg gcggcagcat ggcgacggcg acgaagagga ccgcctgcac ggcgccgatg
    12541 cccagcgcca gcacgtagcg ggaggccagc acggcggagg tgggcgtggg ggtcatccgg
    12601 atgaggcgga ggatgtcgtc gcgccgccac tgcatgagga cgaagccgac gccgaagacg
    12661 gcggcgttgc ccaggcccca ggagaggacg ccgggggcga tgtagctgat gtaggggcgg
    12721 ccggactgct cgacctcctg gccgctgaag atgaggccga agacgacgag gaagatcagc
    12781 gggaaggcga aggtgaagaa gagggtggtc ttgtcgcggg tgtaggcccg gtatccggcc
    12841 tggctgaggg cggcgtaggc gctcatggag ttctccgtgg gtggtggtgc gaagtggggg
    12901 gcgcggggcc gggctcagct ctcggcgggg gccggggcca gggacgcctc gccggtgagg
    12961 gcgaggtaga cgtcctccag gctgggggtg cgggtctgca cgccgtgcag gccgccctgg
    13021 gcgtcgacgg cggcgaggac ggggccggag tcctcggtct ccaggaccgt catgtcgccg
    13081 tcggcggtgg cgcgcagcac gccgggcagg gcggcgccct gtccgggggt gagccggtcg
    13141 gcggggacca gcaggcgggt ggtgccgctg ctggcggcga tcaggcggcc ggggctgtcg
    13201 agggcgcgga cggctccgcc gaccaggatg gcgacccggt cgcagagcgc ctcggcctcg
    13261 tccaggtggt gggtggtgta gacgatggtg cggcccgcgc ccttgagatc gcggagcacc
    13321 ttccacaggt cgcggcgggc ctgcgggtcg agggcggcgg tcggctcgtc caggaagatg
    13381 agctcgggct cgtggacgag ggccgaggcg atggccaggc gctggcgctg gccgccggag
    13441 aggtcgtcga cccgcacgtc accgtggtcg gtgaggccga ccagggcgag ggccttctcg
    13501 gcggcctcgc ggccgacccg gtagagggcg gcgacggtgg tgaggtgttc gcgggcggtg
    13561 aggcggacga agaaggcgct ggactgggtc tgcacgccga tgcgcgggag cagcgcggtg
    13621 tcccggggcc aggggtggtg gccgagcacc gtgacggtcc cggcgtcggc cttgcgctgg
    13681 ccctccatga tctccacgag ggtggtcttg ccggcgccgt tgggcccgag cagcccgaag
    13741 aactcgccgc gggccacggt gagggtcacc ccggcgacgg cctcggtccg cccgtacgtc
    13801 ttgcggacac cgtcgaggac gacggcgccg gcggggtcgg tgggctgggg ggtcatgtgg
    13861 tgctcctcga tcgggtgtgc ggggtgtacg tccggagggc tgggggtcag ctaccggtca
    13921 gcaggtggcg ggcggcggcc cacagggcga ggccggtccc cgcgaggacc agcagcacgg
    13981 ccgccgggta cgccaggtag gcgcggcggg ccggggcggg gtaggcgcgg gcggccgggt
    14041 cgcggcgcag ggcgagcccg aggtaggtgc ggctggcggt gaacaggccg agggtgcgcg
    14101 tgagttgccc ggcgatctgg tacccgtcga gcggcggcag cgggatcagc atggcgaggg
    14161 cctggacggt gccgagcagg acgagggcgg cgcaggcgtc gcgggtggcg tcgtcgggcg
    14221 gggcgaggag ccagagcgcg ccgaacggca gcaggaagag caggttcatg acggctccgg
    14281 cgacggccgt cgcgatgcgg gcccaacggg tcggaaggta tgggtagttg tcgactgtgc
    14341 agtacatgat gaccacgggt agccgccacc gcagtccgat ctcggccacc gtgccgccgt
    14401 ggtgccgggc caccacgccg tgggccagtt cgtgcagggc ggtggagagc cagagcaggg
    14461 tggcggcggc gaccaggagc accgggttct ggaagagcgc ccaggtggcg tcgagcgcct
    14521 ccccggcgcg cagcaccagc gccgcctgga gggcgaggac cagcaggagc agcgggacga
    14581 gcgcggccgg gtggagcagg ggccgcagca cccggtggag ccgggcggtg gtggcgtcgg
    14641 cgtcggccac caggcgcagg gtgccgcgcc acagggtgcg gggctcggcg ggcgcgaggg
    14701 gggcggcggc cgggcggggg gcgccgtcga gcaggccgcg ggtgccgagc agtgcgagga
    14761 gctggcgcca ctgtgcctcg ccgagccgct tgccgtgggc ggcggcgtac tccgtgccca
    14821 gctggtccag ggcgcgggtg ccgtccatcc gggccagcag gaacgcctcg cgcgggccgg
    14881 ccttgaaggc gtggccggtg gcggtgtcct tgacgaggtg gacggtggcc gggccgtcgt
    14941 acaggggccc gccgacgagc acgcccgcgc gcagggcggg ccggtaggag ccggggacgg
    15001 cggcccgttc ggcgggcgcg ctcacgcggt gccctcgcgc agcacccggc ccagcacgtg
    15061 cgagaggtac gcctcgtcgc ggatggtgac gtgcagccgg ttgttggtca tgtgcatgta
    15121 cggggagagg agcagcggca gcgcgacggc cgggtcggtg acctgctcgt cccgggtgcc
    15181 gtcccaggag cggaagatca ggtcaccgtc gagcgtcagc ttctcggcct tctccttgag
    15241 ttcggcgcag tgctcggccc agctggccag gaagccgggc agccggggct tctccccctc
    15301 ctcggtggcg ggggcggtgg cggcgcggac gcgggcgaag cgctccccga ggccgggggc
    15361 gagggcggcg tagttgcggt cgtactcgtc ggtgccgatg aagttggtgc cggggaaggc
    15421 gcggtgccag aactcgtagt agctgtccag gtagccgttg agttcggcct tgtcgggcag
    15481 gaaggtcgcg gccatcacca tcatcagctg ggcggaggtg ccgagcagca cggtgcgcag
    15541 gtggaggttg atggtggcga aggcgtcgat gaccaggtcg ctggagtgcc ggaagtgcca
    15601 ctcggccagc tcgatcccgg ccggcccgcc gtacttgccg tactcgggct cgtacggttc
    15661 ggcgctgcgg ctgttgttgg ggcggatgtt catccggccg tcggcgccgg tgtagtggcc
    15721 gcgttcggca ccggggaact cgatgtcgaa gagggtgttg tagaagtcgt tgaggaagcc
    15781 ggcgtcgacc tcgtagagcg ccgggcgctc gcggaggaag gtgtcgacgg ccccctcggt
    15841 gcggcggcgg acctcggcct ccgcctgggg cgtggcgggc ttgaggcgga gccggacgtg
    15901 cgggccctcc agccagtagt tgatgaagaa gtagccgctg atcagccctt ccgcctccag
    15961 ctcggcgacg agcgggcgga cgcaggtgag caggaacggg cgggggttgg cggcgtagaa
    16021 gacgtgggtg gcctgccagg cgccggactt cgtggcggcc cgggtgccgg tgagggtcag
    16081 gtcggtcatg gcgcggtcct cgtgggggtc ggagcgggca gggtctccac ggccagttcg
    16141 gtgacgtgcc ggccgcgcgg cgaggcggcg tgcagcccgt cctcgtcggg cagcgcctcg
    16201 cggaggacgg cgcgggcctt gtcggtgcgg agcagcgcct cgaaggcggc gagcgagagg
    16261 gggctgtcga agtcgaggta gctcggcttg gcgccggtcg cgccgcgcgc cccgctgtcg
    16321 gagacggtgg cgtagacccg ggcgggcagg ccgtgggccc ggcggaagcg gtgccagccg
    16381 aggaaccagg cggcctcgtc ggtgccgggg gcgcgcaacg gcaggtcgcg ggcgtccacg
    16441 ccccagctgc ggcgggcgag gaccaggctg ccgtggcgga cccggggccg gtgggtgacc
    16501 ccgtcgacgg gcgggcggtc ggggacgccg ccccagacgt tgagcgggga catggaggtc
    16561 ggggagagca gcagcagggt gcgcgggagt tcgggcaggg cgagcgggac gaggtagccg
    16621 aggtagaccg ggatcacctc gcgctccagt cgggccgagc gcagcacgag gcggtcctct
    16681 tcctcgtcgt ggacgaggaa gaggtcgtcc aggccgagcc ggaactccgg ctccagggtg
    16741 ccggcctcgc ccgggccgac gatctcgtac tcggtgaggc gggcgtgcag gttgaggttg
    16801 gaggtgacgg ggccgccggt gacctcggcg aggacggcgc cgggcggcgc ggcctgggct
    16861 ccggcggcga gcagccgctc gtccaggccc tcgaagaggt gggtgaagcg gctgaagggg
    16921 aaggagaggc cgccgtagga gcggttgagg acggcgagcg ggccctcggg ccggtcggcg
    16981 agctggacgt ggtggctcat cggcgcgaag gcgggcgcga gaggggcgag cggcgcggcg
    17041 gtggcgtcga ggagggcgtc gtcgaggacg aggtcgccgt cgccctcgtg ggcggcccag
    17101 cgttcgcgca tcccggccag gaaggtggcg cgggcggcgt ccagggactt cagctcgggc
    17161 aggccgagcc agttctcctc ggggttgtgg tcgccgtcgg ggccgaaggc ggggcgctgg
    17221 gcggtgaagg agaggtactg gtcgaagaag tcctcgtgga agtcgtggac cagcttgacc
    17281 aggtcgtcgc agcgcccgcc gcgcccgaac cgggcggtga agaacccctt gaaggtgagc
    17341 cggtgcggca gggtcaggtc gaaggcgggc agcacccgct ccagccggga gagcggttcg
    17401 cccgcgatct cggcccagcg gccggcggag agggtgaggc cggtgggccc gtcggcgggg
    17461 accgcgcagt cctcgtagag cacggtctgc gggacgcggc gctgctctgc gcccagcgac
    17521 cgctgcacgg cggcgagttc gccccggagc tgttccagga ggagccttct gcggtccggt
    17581 tcggcggcgg cgaacttgtc gacgcaggcc gcggcgggct ccaggcggtc ggcgaggcgg
    17641 tcggcccaca cgcggcccac gccgcgcagg gccgactgga aggcgcgcag cgggtcggtg
    17701 tcgtggacgg tgacgtcgag gcagggcacc cggaccaggc cgagggcgag cagcgcgtcc
    17761 aggtactggg cgacgtccgc ctcggtggcg tcccggtcgg cggcgagcca ggcggagagg
    17821 gcgccgtacc gcagggtgcc gtgctcctcg aagtggccga ggaggcggtc gagggtgccg
    17881 ctgcggcgga ggtagaagag gcggtccttg acggagtcga aggtgacggc ggtggcctcg
    17941 tcgccctcgg tgacccagcg ccgcacgtac cgcacccggt cggcctcgcg cccccacccg
    18001 gaggcgacgg tgacgggcag gtcggcgcgg cgcccggggt cggccaggac ggtggcggcg
    18061 agccggccga cggcggcggt gttgagccgg gcggcggtcg gccaggcgtc ggccacggcc
    18121 agcgggaagg cgccgggacc ctcgtgcggc tccccctcgc tgaaggtgcc gagaccgacc
    18181 ccggtgaagg tggagaaggg gctcgtcttg caggcggtcc ggtacaggta ggacagcagg
    18241 gaacgttcga tcttgcggtg cttcttgtcc ggagtggcgg ccggttcggc ggcggtgcgc
    18301 cggacgtacg cgtcgagtcc cgcgtccagg gtcggcgagg cgagcagcag gcccttgcgg
    18361 agccggtcct ggccggcggc cgcgcagagg gcggcgcggg cgcgggccgt ctcggaggcg
    18421 agcagcccgg cgccctcggc ctcgcgggcg gccagggcgg ccctgcgctc cagccagccg
    18481 gtcagggcct cggcggtgcg cgggtcgcgg gcggcgacca gggcgcgggc ggcgccgggg
    18541 tccttgggga gccggttgtt gaagacctca cggcggagtt tcagcagggc ccggcgctcg
    18601 gcctcgtcct gaagcccgcc gatcagcggg tggaggaggt cgccgagggc ctcgccgtcg
    18661 gcggtgaggc gggcggcggc gtcgagcacg tcgtcggccc agcggcgggc gccgggggcg
    18721 cgcagcgggc ggacggtctc gacgggcagc ccggcggtgc gcaggacgaa ggcctccctg
    18781 gggcggccgg ggcgcggggc gggggcgtcg ggtgcgggca tggcggcggg ggtgcccctt
    18841 ccggaggtca cgtcagctcg tggcggtagt cggcgggggc gggccgttcg tggccggcca
    18901 tcatgatcag cagcggggcc tcaccggtgg cctccagacc cagttcctcg atgtacgaga
    18961 tgttgtcgaa gccgagcgcc accccgcagc ccacgtcgag cgcggcggcg gcggtgtaga
    19021 cggactgggc gacagcgccg atggtggcgt tgaccagccg gtacccgcgg tcgccgaccg
    19081 cgtcgagcac ggcggtggtg cgcacggtcg gcaccagcac ggctccggcc tgctccaggt
    19141 tgtagttgga gaggaagtag ttcttctgga ggaagggccc gggggcgccc tccttgacca
    19201 ggcgcagggt gcccgcgccg gggtcgtagg cgtaggcgcc gggggcgagg tcctcggcgt
    19261 ggttgacgaa gacgtacagc ccggccaggc gtacgccccc ggcgccggtg ccggtgtccc
    19321 cgccgaggta cgagccgtcg gtggcggccc ggcagagggc ggcgaggtcg gcggcggaga
    19381 gcgggcggga ggcgtcgaac cggccgaagc tgctgcggcg ccggcgcagg gcggtgcgca
    19441 cgtcggtggt gagcggcgtc gcggcgggca gcggtgcctc gggcagagcc gggccggccg
    19501 ggtgggcggc ggccggggcg agggcgccgg gggcgggccg gtcgagggcg ccttcggcgg
    19561 tggcggcctg catggcggtg acggcctcga aggtgaggac ggtgcgggag cgctcgacgt
    19621 cccggtggcg cacggcgaac ggggtggccg ggggcgcggc ggccccggtg gccccctgcc
    19681 accgcagcgg caccacggcg aagatcccct cctcctcggt ccgcaccccg agcagccgcg
    19741 cgaggcgctc ctcgtcgaac cagagcgcgg gttccacgtc gagcccgcgc gcccgggccc
    19801 acatccgcca ggtctgcacg caggcgccga ggtccatgga gacggcgtgg aaggagaagc
    19861 tgttgtactt gaaggcgttc tgccagtact tgatggacag gacgaggtac tggtcggtgg
    19921 cgtcgccctc gcccggtgcg cccggcccgg cggcctccag agcggcgcgg acctcgccgg
    19981 tggcgtcccc ggtgagcagg cggcgcatgg cgtggtggcg ggtggcgtag tggtggacgc
    20041 cgggcggcag gggagcggag gggccggaga cccagtagac gctgaccggg tagaggccgc
    20101 cgccggaggc cgagccgcgg gagaagttgg cgagcgggta gtgcgggagg gcgtcgaggt
    20161 cggtgttggc ctggacgccg aggcggcggc cggtcaggcc gtaggagtcg cggagcatcc
    20221 cggagagcgt ggcgaggtcg aagtggcccg gcctgtcgag gggtccgggg ttcagtccct
    20281 ggtcgagggc ggcgtccgcc gggtagccgg agtcgggcag cggcagcagg tcggtgtccg
    20341 ggtagtgctt ggtcttgcgc gggccgtcgg cccagttcgg cacgtggtcg accggctcca
    20401 tgtggacccg gccgcgccgc atgatggcgg cggcgtagtc gtaggcgtac cccacggaag
    20461 gctccctggc ttgtcggggc ggctggctgg tggcgtcggt ccccggtctc aggggaaggg
    20521 gtgcggggcg gggttgaggt cggcgtcggt gaggtcgcgg ccggcgaggc ccgcctcgcg
    20581 cagggcggtg cgcaggcggg gcatgccgag ggcgcgctgg cgggtccagc cgaagtcgat
    20641 ggggagcagg ccggggacga ggacgctgac ggtcctcagg cccagcgccc gctgttcggg
    20701 catggtctgg tcgacgacga ccacgtcgaa gccggcgccg gtgacggctc ccacgcaccg
    20761 ggcgaggtcg tcgcggaggt cgtcggagac gggcggcagc gagccgtcgc cgtacagctc
    20821 ggcgaaggag cgcttggccg ggcggggggt gccgggggcg ccgaggagga agtcggcgtg
    20881 gtcgcccatc tcggggatgc cgtaggcgag cggatggtcg tggagcgcct cgacgcggtg
    20941 gaagtcggtg gccatggcgc gcagccgggc ctcgtcgcgc cgggtgcggc cgggcaggtt
    21001 gacggcgtcg gtggcgatct cgcagagggc gcccgcgacg gccgcctcgg ggtcgagccc
    21061 ggcccccgcg ccgaagcaca tccggcccgg cccgccgtcg gggcggacgg cgacaccggt
    21121 gacgaccggg atcgggaagg tgatccgggt gtcgaagaac cgggcctcgt agccgtacat
    21181 cgcgagccgg tcgaccatgt gccgggtggc ggggctggtg ctggtcgcgg ggtcgatctc
    21241 gggcagcgcg gcccgcccgt accaggcgag gaggaaggcg tcccgctcga cgacctccat
    21301 gagcccgcag tagacggcct cctccaggca gccgccggtg gcgcagccgt tggaggactc
    21361 ctgcacgaac cggttctcca gcccgggcgc gtggtagtag gtgagcacct cggggaccag
    21421 gacggggcgt tcgtcgcgga gcgagtaccc ccacacccag gggatctcgc gtccggtggt
    21481 gaagggcggc acgtgcgggt tggcggcgtg gaacgcctcg tcgtacagcc cggcgacgcg
    21541 tgggtccacg acctgctccc cgcgcgccac gagctggtcg agcgaggccc ggacctcggc
    21601 cttcttcgcg cgtgaccgca tccccgcgta ccgctccagg ccctccagga ccccgatgcg
    21661 caggctctgc ccgaaggtgt cggcgtggcc gccccagaag gtctcgcgga ggtagtcgcc
    21721 ggagcgcatc gagaagcagc cgacggtggc ggaggtcgac ccggaggaga cgtcctggac
    21781 gacggagggc ccgagcgagc cgcagagcgg gttggcgtac ggcgacaggg gcagctcgta
    21841 cgtggcgagg tcgcggacgc ggaagctgcc gggccggtgc ttgggcgcgg gccccagggt
    21901 gagcgtggcg gcctcggcgg tgtcctcctc gacgaccgag cagcgcgggc actccgggtc
    21961 ggggacgagc gggtagtggc gggtccgcag ggtctggagg tcgaccaggt gcacggcggc
    22021 gaacgccccc gtcgccgggc cgcgcccgcc gagccgggcc gcgatcagcc cggccaccgc
    22081 gtcggccccg aacaccgtca ggtacgggtt ctcccccgcc gcccgcgtcc cggcccccag
    22141 ctccagggcc tcccgcagcg tcacactgcg caccgcctgc caccgccgct ccaggcaacg
    22201 ggcacagggc tgctcccgct cgccggggaa gggcccgacc acggcctgcc gcccgtagat
    22261 ccgcaccggc acggcccccg cctcgtacgc ggcgagcggc tcccggaagg cgtcgtggac
    22321 gccgagcggg gcgaggtcga gggggacggg cgtggagtgg gcggccagcg cccggtgcag
    22381 cccggcggcg aaggcggcca ccgggtcgcc gtcggcgcgg cccggcgctc cggccgcctg
    22441 gtcgagggtg tcagcgcgca tcggtgccgc cctcggcggg ggcggccacg gtcagcagga
    22501 cccgggcggt ggcgagccgg ccggtggcga ggtcggccgg agtggtgtcg aggtacaggg
    22561 cgtcgcggcc gctctccccg agccgggcaa ggatctcggg gaaggtggtg gcggcgtcga
    22621 gcgggccgcc cggctccccg gcgagggtga gcgcggcggg cgccaggtcg gtgacgaagg
    22681 ggtcgccgga gtcgggctcc tggccggtct cggcggcgag ctgggcgtcg ccgagcaggt
    22741 cgcgcagggc ggcgcgggcc gcctcgcgcc gggtgaggtc ggcggcggcg gcccagcggc
    22801 cgccgggctc gcgggcgagg acgacggggg cgggcccgtc gccggtcagg tcgagcagct
    22861 ccacgccgag gtcgagcgcg gcggcggtct tgtgcaggaa ctccagctcg gcgtcgcccg
    22921 tggtgtcctg ggcgagcagc acggcccccc tgccccggac ggcgtgcagc acggccgcgt
    22981 gggcgagggc ggcgagcagc gcggccccgg ccgcctcggc ggccgaactc ccggcgcccg
    23041 caccggcggt ggcggccagg tgcgtccgga gccggttgtg cgggccgaag gggcgggcgg
    23101 ccgagacggg cacgcggtgc ggttcgccgg tacgcagcga gagcgcgggg gtcagggcgg
    23161 cggccggggt ggcgtcggtc ccgccgaagg tggcgagggc ggccgggtcg acgggtgcgc
    23221 cgtgcccctc ccccgccacg ggcgcgggca cggtgtggtc gacgtacagg acggcggccc
    23281 ggtgcagggc gcgggtccgc gccccggcga ggtggtggat gtcggcggcg gtcacggcgc
    23341 gcaccgtgcc gtcgggcagg ggaagttcga cgcggctgac cttgagcggg gtctgggtga
    23401 ggtcgtcgtc gtcgaagcgg gtgaagaccc cggtgtgcgg gcggaccagg gcgctcgcgg
    23461 tggcgttgag cgcgtccacc acctcctggg cctcctcggc cccggccacg ctcggcgtgc
    23521 gggggacctc cggggtcccg ggcgaggtca ccgggactcc ggagggggcg cagtgacggc
    23581 agcgcgggtg cgggggcacg ggttcggcga ggacgtccag cgaggagagg tcctggatga
    23641 gcacctgccc gcgcgtctcg gccggctgca ccccgctggt cagccggaac acctcgtacg
    23701 cgaggaggtt gccgcacatc gcggcgaccg gcccggtcag cggccccggc gcgcccgcgt
    23761 cgacgctgcg ggcgccgccc gcgacctcgc tccacagggc ggcggcggtg cccgcgtcga
    23821 cgcccgcgcc gaggcggagc agggcgcagg accagcagcc accggtggcg gtcgcggtgt
    23881 cggcgccggt ggtgagcggg cccatgacca gccgctcgcc gaaggcccag gcgggcagca
    23941 gggtgcggcc ctcggggacg ccctcggtga gcaggcggtg ggtgagcccg gccgcgccgg
    24001 gtccggtgac cacgacgacc tcgtacccgt ccagcgcggc ccagccgggt ccttcggagg
    24061 gatcgggcag ccggcccagg ctcaccgggc agccctcgtc gccgagttgg gccgcttcgg
    24121 cggtcacgtc ggggaattcg gcggccagcc cgaccgcccc gcagccgttg cggaccaggc
    24181 cgagggcgac ccatcgggcc gtctcgtcgg taccgaggac ggcgacgcgg gcggcccggt
    24241 agcgggcgaa ccggtcggga gcggcgtcgg tgtagtggtc gatgtaggcg atctgcgcgg
    24301 cgaaccgctg cccggcggcg tcctcgggcg ccggtctcag cgcgtcggcc tcggggatgt
    24361 cgcgggcgaa gtcgcgggcg tagagagtgc ggaccagttc ggcggccatc gcccgctggg
    24421 ccgggccgaa cccggcgcac acctcgtcga gccggtggcg cccggtcagg tgcggcagga
    24481 cgagggcggc gaaccggtag gcggtgcggc cggtgaggtg gaagccgccg tcggcgttgt
    24541 ggaagaggac cccgccgggg gtctgggtga agagcacgtc gcggcggacc cggggccggg
    24601 tggcggcgag cgcgtcgaag gcgtcggcgg cgggggcggt cgccggggcg ggttcggtgg
    24661 tggggtcggc catcaggggt cacaccttct ctgcggggcg cgggagttcg gggcggtgcg
    24721 cgcgggcggt acggcagtgg gggcaccgcc cggtgcgggc ggggtcgggg gcctgtgggg
    24781 ttgggccgga ggcggccggg gcgcggcccc gcccccgcgc ccaggcccgc agcagcggca
    24841 gcgtgcggta cgggccgggc gggccctcct ccaggaaccc ggcgtcggcg agccggtcga
    24901 ggagctgctc ggtctcggcc tcaccgagcc cgagcgcggg cgcggcctcg tcggccccgc
    24961 aggccggccc gagcgcggcg accctcagga aggcgtcggc gagcgggggt tcgagccggg
    25021 ccagcgcctc cccgagcacc tcggggacgg agagcccggg ggcgtcggtg agggcgagcc
    25081 gtccggcctg gtcggggccg agccagcggg cggagtcggc gaggccgagc ccggggcggg
    25141 tcagcagccg ggccgtcatg atgcgcaggg ccagcgggtg gtggccgcag ccctcggcta
    25201 tgcggcgggc ctcgtccggt tcggcgtcga cgcgttcggc gccgaggacg gagcggagca
    25261 gggtgtgcga ctcggccggg cggaacggcc cgagccgcac cacccgcccg ccgtgggtgg
    25321 cgaccagccc ggcgaggccg cgccggctgg tgaccacgac ggccccgccc gtacaggcgg
    25381 cgagcagcgg ccgcacctgg tcggcgccgg ccgcgtcgtc caggatcagc agggtggcgc
    25441 tgccgggcgg gcgggccgcc agggcgcggg tgagctgtcc ggcgacggtc tccgggtcgt
    25501 ggggccgccc gtccgggccg gtcaggcgga tcagcagccg gccgccgggg aaacggtcgg
    25561 cgagctgcgt ggcgacgtgc cgggccagcg cggacttgcc gatgccgggg gcgccggaga
    25621 ggacgacggt cagcgggccg ccgggccggt gggcggtgtc ggcggtgagg tgggcggtga
    25681 gcgcggccac ctcgggagcg cgcccggtga agtcggggac gggggtgagc ggggcgaccg
    25741 gcccgggctc ctcgctcccg ggtgcggcgg gcgcgtccgg gagcgcggcc gggcggccgt
    25801 cctcctcccc ggcgggcccg gcggcgaggg tgtcgccgcg caggatggcc agttcgagcc
    25861 gctggagggc ggcgcccggg tcgaccccga gctcctggag caggtactcc ttgacgcgcc
    25921 ggtactcggc gagcgcctca gcctggcggc cggtccggta cagcgcctcg accagctgct
    25981 cgtggaaccg ctcgtggccg gggtgggcgc gggtcacctc ccagaggtcg cccagcgcct
    26041 ccccgcaccg cccgagccgc aggtggaggc cgcagagccg ttccacggcg cgcagccgtt
    26101 cctcggccag acgcggcacc tcgtcacggt ggagcaggtc ggagcggacg ttggcgagca
    26161 gcgggccctg ccagagcgcc agtgcgtcgc gcagcgacgc cagttcggcc tgcggatcgt
    26221 gggtgagggc ggcggcccgc cggacccgct cccggaaccc aatgaggtcc agggtgtgcg
    26281 ggccggcggt gatgcggtag ccgccgggga cggcctcgat cggcgtctcg gtgaccccgt
    26341 gcttggtgaa gagccgccgg agcctgagga cgcaggtctg gagggcggcc ttggcggtgg
    26401 ccggctgctc ctccccccag atggcccgct ggagatagtc ggcggagacc acggagttgg
    26461 cgtgcaggag cagcgcggtc aacaggacgg tgggcttggc gggctggagg accaccgact
    26521 cggggccgtc gtgcagcgag agcgggccga gcagctggaa ccgcatgccg gcgcctagtc
    26581 ccagccgttg accagcttgc cgtacccggg atcggcccga acgccgtccc agccgttgac
    26641 cagcgggctc accgggacgg gggcggcgtc cggcgcctgg gcgacggcct gcccggcccc
    26701 gagggcgagc acggccacgg ccccggcgag ggcggcggca gccctggccc ggcgggggcg
    26761 gacggaggag acggggtgcg gacagtgggc gttacggttc ccggacacgg ttctccctgg
    26821 agagtctggt catggctcgt gggcaactgc gcgaacaggg ctcgccggtg tgcggcccgg
    26881 cgccccgggg ctgggccgga gcggggatgg tggggggggt ggctctgtac gaagcggggc
    26941 ggggcgccgt ggtcacgggc gcccgcctga cgggccgtcg ggcggtgttg acccgaccat
    27001 gccagcattg acttctgccg tggtggacgc gcgttgacag cttgttgcag ccgctccggc
    27061 agcatcgtgc aaccaggatc ggcattcggc gcgatccgcc cgaaccgggt ccgtcccacg
    27121 ccgccccgca cccgttcggg cagctgcccg cccgccggac gccctccccg ccggcgcccc
    27181 gccgatgaga aggtgtcccg gaatcggtgt agggggaacg gaatcgccgc cccccgcacg
    27241 tgaggagagg acgaccgtga acgagggccc cgcatccggc acgcccgacc tgccccgccc
    27301 gcgcggcccc caccccgggg agtccgggcc gaagccgccc gccccggccc cggacgcccg
    27361 gcgcggcgcg gtcgtcgccg ccctcatgct ctccatggcg ctggcggcac tggacggcac
    27421 catcgtctcc accgccgtcc cgcagatcgt cggcgacctc ggcggcttct cctccttctc
    27481 gtggctcttc gccggctacc tgctcgccgt caccgtgacc ctcccggtct acggcaagct
    27541 ctccgacacc ctcggccgca agccggtcct catcatgggc tcggtcctct tcctcctcgg
    27601 ctcgcttctc tgcgccgtcg cctgggacat gacctcgctg atcgccttcc gcgtcgtcca
    27661 agggctgggc ggcggcgccc tccagggcac ggtgcagacc ctcgccgccg acctctaccc
    27721 gctcaaggaa cgacccaaga tccaggcgcg gctctccacc gtctgggcgc tctccgccgt
    27781 cgcgggcccc ggcctgggcg ggctcctcgc cacctacgcc gactggcggt ggatcttcct
    27841 catcaacctg cccgtcggcg ccgtcgccct ctggctcatc atccgccacc tgcacgaacc
    27901 cgtccgcgag cggaccggac cccgcccccg gatcgactgg gccggcgcgc tctccatctt
    27961 ctgctgcggc gccgtgctgc tcaccgcgct ggtccagggc ggtgtcgcct ggggctggct
    28021 ctcgccgccc tccctcgccc tcttcggcgc cggcgccgtg ctggccgccg tcacggccct
    28081 ggtcgaacgc cgggccgccg acccggtcct ccccggctgg gtctggcgcc gccgcaccat
    28141 cgccgccgtc aacctcgccc tcggctgcct cggcctgctg atggtcgccc cgaccgtctt
    28201 cctcccgacg tacgcccagt ccgtcctcgg cctcgcgccg gtcgccgccg ggttcgtcct
    28261 ctccgtgatg acgctctcct ggccgctggc ggccgccctc agccagcacg tctaccggcg
    28321 catcggcttc cgcgacaccg ccctcgtcgg catcggcggt gccaccctcg tcctgctggc
    28381 cttcccgctg ctgccgtacc cgggcagcgg ctggcagccc gccctgctga tgctggcgct
    28441 cggcgccgcc ctcggcctct tccagctccc gctgatcgtc ggcgtccagt ccaccgtggg
    28501 ctgggaggag cgcggcacca ccaccgcctc ggtcctcttc tgccgccaga tcggccagac
    28561 cctcggcgcc gccctcttcg gcgccgtcgc caacggcgtc ctcaccgccc gcctcggcga
    28621 cacctccggc gacctcgacg cggtcgcccg cgccctggac gaaccgggcg ccatggaccc
    28681 ctcgaccgcc gacaccctgc gccgcgccgt cgcctcggcc gtggagaccg tccacctcgg
    28741 cgcggcctgc gcgggcgccg ccgccttcgt cctcctgctc agcctggccc cgcgccgctt
    28801 cccagtacgc ggggagcaca ccggcccggc ctccgccgaa cgggcctgac ccccgcccgc
    28861 ccgtccggtc agccggccgc cagccccgcc aggtagccgt cgaccagcgc gacctgccgg
    28921 acgggcggga actcctgggg cgcgaacagg gcctgcacca ccagccccag cacgaaactc
    28981 tgcgcggccg ccgccacgtc cccggcctcc ggcccggcgg gcagctcccc cgaccgctgc
    29041 gcctcggcga cgtacccggc catccgctcc cgggcccgcc ggtaccgcgc cgcgtgctcc
    29101 gccgccagtt ccggatcggc cagcgccacg tcccaggagc cgacccagat ccggttgttc
    29161 gccgcacccg gcccgtcgag cggcagcacg tcgagcagca ccgcccgcag ccgcaccagc
    29221 cccgacgcct cccccacccg ctcctccgcc ggccgcggcc gccccgccga ccgcccgtcg
    29281 agcacctcca gcgcgtgccg caccagcgcc cgcttgctcg ggaagtagtg cgtgaccagc
    29341 cccgtcgtgg cccccatctc cgccgccacc gcccgcagcg tcagcccccc gaacccccgc
    29401 gcggccagca cccgccacac cgcctcggac acatcctccc ggcgtgcgtc atggtcccca
    29461 cgagctggcg tcatacccgg tacggtacat acccaacgct tgttacgtac cactcgcccc
    29521 ctagccccag gacccgccgt gtacgccata cccctcgccc ccggcgccga gctgcgcccc
    29581 ctggaaccct ggcaggcccc cgagttcctg gcccacatcg accgggcccg cgcccacacc
    29641 gacccgtgga tcccctgggc cacctactcc accgacctcg actcggcccg cgccaccctc
    29701 cagtcgtacg ccgacaagca ggcggccgac cggggccgtg tcttcggcat ctggcgcgag
    29761 gggaccctgg tcggcggcgt catgttcgtc cgcttcgacg ccgccggcgg cacctgcgag
    29821 atcggcgtct ggtcggaacc ggcgggcgag ggcctcggcc tgatcaccgc cgccgcccgc
    29881 cacctcctgg cccacgcctt caccacccgc ggcctgaacc gcgcggaatg gaggaccacc
    29941 ccccgcaaca cccgcagccg cgccgccgcc cagcgcctgg gcatgaccct cgacggcacc
    30001 ctccgcgaac actcctccta ccgcggcgaa cgcctcgaca tcgaggtgtg gtcgctgctg
    30061 gcacgggagt gggagcggaa ggagcgggcg gaccgggcct agagagcccg gcccgccact
    30121 cacccagacc ccgccccgtc aggcgtacgg gtcgaagtcg atccccgagg gcttcgcctt
    30181 ctccaggtgg gagccgaaac cggcgtcctt caggccgaag ttggcgctgc cccagtcgtg
    30241 ctggctcagc ctgtcgcgca gaccggcggg gtagccctcc cagccgacga gggccgggta
    30301 ctgccaggtg ccctggtggt tctccggcgg ctcgtcgttg gcggtggcgg cgcggaagca
    30361 gtgggtgctg gcgccgtcct tgtggtagac gatcttcggg tggctgccgt cccagcggat
    30421 ggcgtcgcgg tcgtgcacct tgaaaccgcc gtgcgccgag gtggccacgt accgggcctc
    30481 gccgccgttc acccagacca ccacgtgctc ccagtcgtgc cggtgcccgc cgagcccgct
    30541 ccccgcgacc gcctggtcct tctcgaagta cgagccgtag aggacggcgc accagtcacc
    30601 gtcgcacttg gcgcgggagt aggtgttggt gttgtcgagg tcccaggcgt cccggcactg
    30661 cccgttgagg gcgccggagg ggttgagtcc gccgttgaga gtgccgtcgg gaccgatggc
    30721 gggggtggcg tagcagccgt cggtgtcgta gtcgtaggcc ggctggtacg tctgctccag
    30781 cgcgtcggca ctggccggga gcgcggcggg cgggtcggcg tgcgcgctgc cggcgaaggc
    30841 gacgacgagc ccggtggcgg cggcgagggt gaacgcggct ctgcggatgc gggaacccgt
    30901 attcaagacg tcctcctgag gacggtgggg ggatgacaca cggacacagg cagatttgac
    30961 atgcccaact caccctcgcc gaaccacggg agcgcggggt gaccgtgggg ccacaactgg
    31021 gcgtgcggga agggaagatg gggagccccc acgcacagga ggccggtccc ttgcgcaccc
    31081 tgcacgtcgt cacccacccc gaggcggccc gccacgtcga gggagtcgtg ggaggctggc
    31141 cccctgacct gtcaccagaa cctccaacag cccgaggaga cagacacgtt gagatgtcgc
    31201 accgccgcca cctccgccgt cgcggccctc accctcctgc tcaccggatg cggcgccgac
    31261 agcccctacg aggccgggta cgcccacggc caggaacgcc ggggcaccct cggcggtgac
    31321 ctcttcggcc agatcttcca ctgcgccacc tgggccaagg agcagtacga ggagaaggcc
    31381 gaccggaacg cgttcaagcg gggctgccag cacggcatca acgacctgcc gtccaggccg
    31441 taggtaccgc aggccgggag cagggaccgg gtcccactcc cggaccggtg gcacaatccc
    31501 accccatgcc caccttcacc gcccccgacg gcaccccgct cgcctgccac gccgcaggcg
    31561 acggcccgcc cctcgtctgc ctgcccggtg gcccgttcca ccccgccgcc tacctcggtg
    31621 acctcggcgg cctcaccgcc caccggcggc tgctcgggct ggacctgcgc ggtaccggcg
    31681 cctccggggt cccggccgac cccgcctcgt accgctgcga ccgccgcgtc gcggacgtgg
    31741 aggcgctccg gcgccacctt ggcgtggacc gcgtcgacct gctgggccac tccgccgggg
    31801 ccaacctggc cgtccgctac gccgagcggc acccggacca cgtcgaccgg ctgatcctgg
    31861 ccaccccgag caccttcgcc gtcgggctgg acgtgcccgg gccggtccgc gcggcgacgg
    31921 cccggctgcg cgagggcgag ccgtggttcc cggaggcgta cacggcgctg gaggaggtgg
    31981 cggcgggacg cgccacgccc gcctcctggg aggccatggc cccgttcatg tacgcccgct
    32041 gggacgacga ggcccgcgcc caccgcgcgc tgggcacccc ctggcgcggc accgaggccg
    32101 ccgccaccta cggctccgag ggcgccttcg acccacccgc cacccgcgcc gccctggccg
    32161 ccttcacccg cccggtcctc ctcgtcgcgg gcgaactcga cctcaactcc ccacccgagg
    32221 tcgtcacttc ctacgccgcc cgcttcccgg acgccaggct gacggtcctg ccgggcgtca
    32281 gccacttccc ctgggtggac aatcctccgg cgttcgctgc ggcggtcagc gatttcctgg
    32341 gccggcgcac gtcctgaacc gggcaccacc cccgtcatgc gccgccgcac gctacggggc
    32401 ggcgagccgt tccgggcagg gggcgggccc agagccctct ggcactgctc ccgctccccc
    32461 tacgccacgt ccggctccgc cccgcccccc ggctgcttac gccgagcccc cggcagcgcg
    32521 gtccgggcct ccggggcggc ctcggcctcc ggggccgccg gcacccccac cacgccccgc
    32581 cccgtgaggg cggccagcgc tgtccggatg tgttccatgc gggcccgcag tgcctcgcgc
    32641 tgctcctcgt ggtcgcggac gaggcgttcg gcctcggcgg cgacgcggtc ggcggtggcc
    32701 tgggcctgct ggaggagttc ggcggcctgg gtctgggcct cctggtcggt gcggcgtacg
    32761 gcttcctcgg cctcggcgtg atggcggcgg gcctcggcga ggacggcgtc gccgtggtcg
    32821 tcgagggcgc cctcgtggcc gcgtgccacg gtgtcccgct cggccagctc gcgctcggcc
    32881 tcggcctccc gggcagcgag gtcgcgctcc tggccggcga gggtacgggc ggtcagctgc
    32941 cgggcctcgt cgagggcggc ctcggccgcc gcccgctcgg cctgggcctc ggcgcgggcg
    33001 tcggtgagca gctggtgggc ctcggcgcgc gcggcggcga ggcggtcgtc ggcctgccgc
    33061 tcggcctcgg cgcgggtctc ggcggcatac cggcgggcgg cctcgcgcag gtcggcggcg
    33121 gcctgctcgg cggcggcggt gagggcggcg gcctcggccc ggccggccgc gtccagggcc
    33181 tcggactgct cctggacgag ggcgtagagg cgctgggcgc gctcgccgag gttgtcgtag
    33241 gtgggttcgg agagggtggc gacggtctcg gcgaggacgg cggcctcggc gccgagccct
    33301 tcggcgaggg cggtgagccg ttcggcctcc gcgtgcgcct cgtcacgctc ccgctccagg
    33361 gcggcgacgt actggtcggc ctgggccggg cggtagccgc gtccccgtat cgtcgcgaag
    33421 ccgtgcggcg acgccggtgt actgctcatc gtccgattcc tcccggtccg cgcggaaccg
    33481 ctcgtgccac gccgcgccgc ccggccgacc accccgggcc ggccgccgcg cgagggccac
    33541 ggcaccaccg tgggcaccgt atccacatcc tttcgctcaa ggatgcgtca tttcaggtca
    33601 gaagtcggaa tcgggcgatc ttcgcggagc gccacgaaga gttctccggc ccgccggcgg
    33661 tcccagacga ccacgtcccc ggctcccggg acctccccct cggaccgcag cgggacggtc
    33721 agcgcccgct cctcgtcgcc ggccgcgccg cgcagccccc ggccgagccg gaagaggtcg
    33781 ctcacgtcgg cccgccggtc gacggtgacc gcgtcgaggg aggcggagag gaagggtccg
    33841 gcccgccacg ggttgagcgc caccgccggg ctcgaagcct tgtcggcgac ggccgagacc
    33901 agctgccgct ggcgccgcac ccggccgagg tcgccttcgg ggtcgctgta gcgggcccgc
    33961 acgtaggaga gcgcctggac cccgtccatc tcccggcagc cggccgcgaa gtccgccccc
    34021 gacttccggt cgcgcagccc gcccgccggt acgcagatcc gcaccccgcc gagcgcgtcc
    34081 accacgtcga cgaagccgag gaagtcgacc tccgcgaagt ggtccagccg cagccccgtc
    34141 gcctgctcga cggtccgggt cagcagcttc ggcccgccca gcgcgaaggc cgagttgatc
    34201 ttcccctgcc cgtgcccggg gatcgccacg tacgagtcgc ggggcagcga gaccatcgtc
    34261 gtgccgtggt ccccctggtg gacgatcatg agggtgtcgg tgttacgcac ctcgtccgag
    34321 ccgacgtgca gctcgcggcg ctgctcgggg gtgagcgtgg cgcggctgtc cgagccgatg
    34381 agcagccagt cggtgccccg cccggcctcc ggccgccccg cgtactcccc gaaggcgtcc
    34441 gtggtccgta cccgtccgtc ggcccagaag tacaccgccg tccccgccgc ggccaccacc
    34501 acgaccagcg ccaccaccgt ccacagcacc acccacggcc accgccgccg gcgcctgcgc
    34561 ccgtcccccg cccccggccc gtacgtggtg ggcggcggcc agccgcccgc cgctcccgct
    34621 cctgcctcgc ccgcgcccgt catgccggca tgatccggcg gccccggcgg cgg
//
