LOCUS       NZ_CM002273            21044 bp    DNA     linear   CON 11-AUG-2024
DEFINITION  Streptomyces sp. PVA_94-07 strain PVA 94-07 chromosome, whole genome
            shotgun sequence.
ACCESSION   NZ_CM002273
VERSION     NZ_CM002273.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. PVA_94-07
  ORGANISM  Streptomyces sp. PVA_94-07
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7007517)
  AUTHORS   Ian,E., Sekurova,O.N., Malko,D.B., Ruckert,C., Borisova,M.E.,
            Albersmeier,A., Kalinowski,J., Gelfand,M.S. and Zotchev,S.B.
  TITLE     Draft sequence of Streptomyces sp. PVA 94-07, a marine actinomycete
            isolated from the sponge Phakellia ventilabrum collected in the
            Trondheim fjord (Norway)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7007517)
  AUTHORS   Ian,E., Sekurova,O.N., Malko,D.B., Ruckert,C., Borisova,M.E.,
            Albersmeier,A., Kalinowski,J., Gelfand,M.S. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAY-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Assembly Name                     :: PVA94-07.23
            Genome Coverage                   :: 158.81x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000495755.1-RS_2024_08_11
            Annotation Date                   :: 08/11/2024 02:29:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,173
            CDSs (total)                      :: 6,079
            Genes (coding)                    :: 5,859
            CDSs (with protein)               :: 5,859
            Genes (RNA)                       :: 94
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 220
            CDSs (without protein)            :: 220
            Pseudo Genes (ambiguous residues) :: 0 of 220
            Pseudo Genes (frameshifted)       :: 97 of 220
            Pseudo Genes (incomplete)         :: 166 of 220
            Pseudo Genes (internal stop)      :: 15 of 220
            Pseudo Genes (multiple problems)  :: 55 of 220
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:06:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2091936
            Orig. end                         :: 2112980
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CM002273.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Department of Biotechnology,
            Norwegian University of Science and Technology, 7491 Trondheim,
            Norway.
FEATURES             Location/Qualifiers
     region          1..21044
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="12"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21044
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21044
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11044](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11044)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(275..295)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.7"
                     /tool="antismash"
     gene            638..1588
                     /locus_tag="B590_RS08665"
                     /old_locus_tag="B590_08780"
     CDS             638..1588
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415540.1"
                     /locus_tag="B590_RS08665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08780"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_023417125.1"
                     /transl_table=11
                     /translation="MTASITRRPRPLRSRLAAAGAITAAGALLLTGCGDQTAGADKGGE
                     KETTAPLADKLPKKYQDSGVVKVGSDIAYPPVEFKDKDGKTVGLDVDLAAALGEQLGVE
                     LKFENGTFDTLLGGLRSKRYDVAMSAMTDTKSRQEGLDSETGKKVGEGVDFVDYFTAGV
                     SIYTNKGKDQGIKTWQDLCGKKIVVQRGTVSHDLAKAESKKCEKGEIKMETFDNDQQAQ
                     TRLRSGGADAGSSDFPVAAYAVKTSGGGDHFELVGEQVEAAPYGIAISKSNPELRDAIK
                     AALDAIIENGEYDKIIKKWGVEDGAVTEAVVNGGK"
     gene            1631..2566
                     /locus_tag="B590_RS08670"
                     /old_locus_tag="B590_08785"
     CDS             1631..2566
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415538.1"
                     /locus_tag="B590_RS08670"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the opines
                     (in Agrobacterium) octopine and nopaline, etc.; The
                     N-terminal region of this protein, as described by
                     TIGR01726, is a three transmembrane segment that identifies
                     a subfamily of ABC transporter permease subunits, which
                     specificities that include histidine, arginine, glutamine,
                     glutamate, L-cystine (sic), the opines (in Agrobacterium)
                     octopine and nopaline, etc; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="B590_08785"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_229360172.1"
                     /transl_table=11
                     /translation="MTKKDPEATPPGPAPTRAAPIKAVPVRHYGRYVSALIALAALGSV
                     VYAFSQGDINWAFIPDYFFNDRILSGVRETLILTFLSMVIGVVGGVLLAVMRLSKNPVV
                     SSIAWFYIWFFRGTPVLVQLFVWFNLGFVFEYMNLGPFYKDEWSDFMTPFLTALLGLGL
                     NEAAYMAEICRAGLLSVDEGQTEAAHALGMSQGKTLRRIVLPQAMRVIVPPTGNEVINM
                     LKTTSLVAAVQYYELFKHAQDIGMTSGATVEALFLAATWYLILTSILSVGQYYIERYYA
                     RGSLRQLPQTPWQKVRAHLTSLSSRSEVTR"
     gene            2563..3324
                     /locus_tag="B590_RS08675"
                     /old_locus_tag="B590_08790"
     CDS             2563..3324
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973712.1"
                     /locus_tag="B590_RS08675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08790"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_023417127.1"
                     /transl_table=11
                     /translation="MTAMVKAEGVHKSFGQVEVLKGIDLEVATGEVFCLIGPSGSGKST
                     FLRCINHLEKINAGRLYVDGDLVGYRQKGDKLYELKDTEVALKRRDIGMVFQRFNLFPH
                     KTALENVMEAPVQVRGVSKAAARERAGQLLERVGLSDKAGNYPSQLSGGQQQRVAIARA
                     LAMDPKLMLFDEPTSALDPELVGEVLDVMRQLAEEGMTMIVVTHEMGFAREVGDSLVFM
                     DGGVVVEAGDPREVLTNPQHERTQSFLSKVL"
     gene            complement(3417..4229)
                     /locus_tag="B590_RS08680"
                     /old_locus_tag="B590_08795"
     CDS             complement(3417..4229)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893572.1"
                     /locus_tag="B590_RS08680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08795"
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="WP_023417128.1"
                     /transl_table=11
                     /translation="MTDAETAPTGTTDAGAVQTGATPGADWAAWQISWDQQQEWYLPDR
                     EERFRVMLDMVEAVAGSEPRVLDLACGTGSITDRLLKRFPKAQSTGVDLDPALLTIAEG
                     TFAGDDRVTFVTADLKDPHWPALLPHDSYDAVLTATALHWLHSEPLAALYGQIAGIVRD
                     GGVFLNADHMPDPATPRINAADREQRHRRMDEAKAEGAVDWASWWQLAAADPVLAGPTA
                     RRFEIYGEHADGDTPPAEWHARTLREAGFTEARTVWQSPSDAMVLGLK"
     misc_feature    complement(4250..4266)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.14"
                     /tool="antismash"
     misc_feature    complement(4316..4331)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            4324..4920
                     /locus_tag="B590_RS08685"
                     /old_locus_tag="B590_08800"
     CDS             4324..4920
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470753.1"
                     /locus_tag="B590_RS08685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08800"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_023417129.1"
                     /transl_table=11
                     /translation="MELASYSDYALRLVNSEEPARGTDTLTSVDAVRALFGASTQAARR
                     ATEADVTRFRSVRGRLRAVFEAAAGGDQQQAVHLLNALLLEFPVSPQISGHGERDAEGR
                     PDWHMHLADHPSNATSGYAAIAAMGLAFHLTEFGADRLGLCEASPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRRESDTSERTGRTAE"
     gene            complement(4857..5231)
                     /gene="sodX"
                     /locus_tag="B590_RS08690"
                     /old_locus_tag="B590_08805"
     CDS             complement(4857..5231)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470752.1"
                     /locus_tag="B590_RS08690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08805"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_346016928.1"
                     /transl_table=11
                     /translation="MVPTLESGDWLLVRYGARVRPGDVVILRHPFQQDLLVVKRAVERR
                     EGGWWVLGDNAFAGGDSTVYGVVPRAMVLARVTARLRPRGTAGGGGEPVRGMRATLGWA
                     YSAVRPVRSDVSLSRRLRAR"
     gene            5505..5900
                     /gene="sodN"
                     /locus_tag="B590_RS08695"
                     /old_locus_tag="B590_08810"
     CDS             5505..5900
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="B590_RS08695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08810"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_023417131.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMQAN
                     DDPQFQTRAIVIKEQRAELAKHHVSVLWSDYFKPPHFESYPQLHQLVNDTLKALSAAKG
                     SSDPATGQKALDLIAEIDRIFWETKKA"
     gene            6038..7102
                     /locus_tag="B590_RS08700"
                     /old_locus_tag="B590_08815"
     CDS             6038..7102
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552841.1"
                     /locus_tag="B590_RS08700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08815"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_023417132.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.6e-12, bitscore:
                     44.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILRIRGVVLPERVERTFWTDGEVLRTEPPAGPGAAREVESVVDG
                     GWLVPGLVDVHTHPGAEEPEDGFDEAALRRHLEAHRDAGVLLVRTPGTMEPMPGWVDTA
                     PELPRVRSAGRWLATPGRFFPGVGRDLSEEQLPGAAVEEATAGSGWCKIIGDWRWDEPA
                     VPLEVMTEAVTAVHAAGGRVAVHCQTAEGSRNAVLAGADSLEHGMHLDPALLDLMARQG
                     TAYIPTLGAFSGSAEVWRARERSAKRSAWLEGWAGMVANVRAAHEAGVTVLAGTDTFPC
                     GTVAAESRQLLDAGLPAEEAVGAASWAARSWLGLPGLADGVPADLVAYGRDPVALPEVL
                     EHPARIVLRGRVVR"
     gene            complement(7234..7602)
                     /locus_tag="B590_RS08705"
                     /old_locus_tag="B590_08820"
     CDS             complement(7234..7602)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893576.1"
                     /locus_tag="B590_RS08705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08820"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_023417133.1"
                     /transl_table=11
                     /translation="MLLHIDPGSPVPLGDQVAAAARAAIASGGFAPGDRLPAARTLADS
                     LGVNVHTVLRGYQQLRDEGLIELRRGRGAVVARTGTVSSRAALLPHARTLVAEARSLGL
                     GEKEVLALVRETLAEQPA"
     gene            complement(7605..7760)
                     /locus_tag="B590_RS33310"
     CDS             complement(7605..7760)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B590_RS33310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_255219942.1"
                     /transl_table=11
                     /translation="MPKRSGLVNRSGEALVVRKTGDGREFAVTVDDAGTAAALLNTLAE
                     RRPETR"
     gene            complement(7760..8599)
                     /locus_tag="B590_RS08710"
     CDS             complement(7760..8599)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B590_RS08710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_255219943.1"
                     /transl_table=11
                     /translation="MTATGPPYRVPRRLVALVALPFVVTTAVVAAVHAGMRDRLPGELA
                     VHFGPGGAADRFETPGQFLVAMAAMLLLGGAAWTAMVAWSGRGGGGGTGVATAAGWGLA
                     AFLGTIAVLVLRLNAGAARAAGLSLPLWHLGVAFAVGLAGGLLGHALVRTMVPDWPPSR
                     GENGTERLDLPREGRAGWARRTSSVPMLLGGVVLMVGALAPLTVSAMPWWAAIVLLLGG
                     LLLVLMAQADVVVGQRGLTVRLCGLHWPRLSVPLDRVATAQARPVDPLGEFGGWGYR"
     misc_feature    8671..8686
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            8816..9157
                     /locus_tag="B590_RS08715"
                     /old_locus_tag="B590_08835"
     CDS             8816..9157
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415525.1"
                     /locus_tag="B590_RS08715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08835"
                     /product="DUF5713 family protein"
                     /protein_id="WP_033951099.1"
                     /transl_table=11
                     /translation="MAVAGERVAERKFLRGLYEDPYFPDRVLDQGVAILTALCERIEAE
                     RPADLAALYVLTDAATEEFNALEAAFEAAGSEIETVAREEIAEEFWVIASAYGFAAADP
                     ERLVGARYW"
     gene            complement(9196..9789)
                     /locus_tag="B590_RS08720"
                     /old_locus_tag="B590_08840"
     CDS             complement(9196..9789)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950792.1"
                     /locus_tag="B590_RS08720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08840"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_033951008.1"
                     /transl_table=11
                     /translation="MGVATRTAEAADRDLVAALLDTAFHDDPVSSWVFPEEEHRRAVHG
                     LFMGCFLDAALAAGRVDLLEDGSAAALWLSVPAGEQEEDDMPALMRRTADPDNERAELV
                     GRLTGAIHPTERAHAYLLLIAVAPDRQGEGLGTALLTPVLEQCDRDGLPAYLEASSARS
                     RELYLRLGFTDRGEPLRLPDGPLMWPMWREPTAG"
     gene            complement(10001..11044)
                     /locus_tag="B590_RS08725"
                     /old_locus_tag="B590_08845"
     CDS             complement(10001..11044)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415521.1"
                     /locus_tag="B590_RS08725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08845"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_023417136.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.4e-61, bitscore:
                     205.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHITQSRTDSHEAAEILDEARAVVGPELRRAVDTLPAPIRRVAR
                     YHFGWEDAAGLASGANGGKAVRPALVLAAVHALGGRPERALRSAAAVELTHNFTLLHDD
                     VIDRDRTRRHRPTAWTVFGDADAILAGDALQSLAQQWLAEDPHPRAGAAVARLTRCVIE
                     LCAGQHTDCALEDRAPTEVSLDECLTMAESKTGALLGCACALGALHADAEPDQVNALDA
                     FGREAGLAFQLIDDIIGIWGDPSRTGKPAGADLTARKKSLPVVAALTSGTAAGAELAER
                     YAGPPEPDELARTVALVEAAGGRDWAQAEAADRMGRAVQQLSLAVPDPARAGGLLSLAE
                     FVTRRSY"
     gene            complement(11562..11966)
                     /locus_tag="B590_RS08730"
                     /old_locus_tag="B590_08850"
     CDS             complement(11562..11966)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950790.1"
                     /locus_tag="B590_RS08730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08850"
                     /product="hypothetical protein"
                     /protein_id="WP_023417137.1"
                     /transl_table=11
                     /translation="MNRTHHGPPGRPSAQGGGPGATAEPATSGQAGGGFRATVLRAGRW
                     AFTAPLRLLCTTLARLLPGTRPGGGGPEDGDALPGDLATPRGPAEGRHPASSPARRKHA
                     PSPYCAMPHVPRVARCPHRPSPAPRRLGRR"
     gene            complement(11977..13383)
                     /locus_tag="B590_RS08735"
                     /old_locus_tag="B590_08855"
     CDS             complement(11977..13383)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893580.1"
                     /locus_tag="B590_RS08735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08855"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_023417138.1"
                     /transl_table=11
                     /translation="MSVGEEIRAEQATPQQSLATSAARNLATTTKSVPQMQEISSRWLL
                     RTLPWVDVQGGTYRVNRRLSYSVGDGRVTFVKTGDRVQVIPAELGELPALREFQEQDVL
                     GELASRCEQREFEAGETLAPFGSRTDAVFLLAHGRVEKIGTGPYGDDSVLGVLADGAYF
                     GEQALTDPEAIWEYTARAATHCTVLVLPADQVAQVAERAEPLAAHLRQLRSLPQQRTNK
                     YGEAPIDLSAGHVGEAVLPGTYVDYEASPREYELSVAQTVLRIHSRVADLYNQPMNQTE
                     HQLRLTVEALKERQEHELINNREFGLLNNCEYDQRIQPHAGVPGPDDMDELLSRRRGSK
                     LFLAHPRAIAAFGRECTRRGIYPESVEVAGNRVPAWRGVPIFPSNKIPVTEARTSSIIC
                     MRTGEEDQGVIGLRQSGIPDEIEPSLSVRFMGISEQAIISYLVTTYYSAAVLVPDALGV
                     LENVEIGRWH"
     misc_feature    13535..13551
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     gene            13571..14032
                     /locus_tag="B590_RS08740"
                     /old_locus_tag="B590_08860"
     CDS             13571..14032
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950788.1"
                     /locus_tag="B590_RS08740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08860"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_023417139.1"
                     /transl_table=11
                     /translation="MRLTRFTDLALRVLMRLAVENPKATADLPTTREVAAGMRVPYTHT
                     AKAVARLQHLGLVEARRGRGGGLALTTAGRSASVGALVRELEGTGDVVECEGAEPCPLR
                     SACRLRGALRQAQEAFFATLDPLTVDGLAASPTGPVLLGIARSRAPDEL"
     gene            14157..15380
                     /locus_tag="B590_RS08745"
                     /old_locus_tag="B590_08865"
     CDS             14157..15380
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642378.1"
                     /locus_tag="B590_RS08745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08865"
                     /product="globin domain-containing protein"
                     /protein_id="WP_023417140.1"
                     /transl_table=11
                     /translation="MLTERSAATVRATLPAVGAAIGEISGQFYDRLFTDRPELLRDLFN
                     RGNQAAGTQRQALAGSIAAFAGHLLDHPDSRPDAMLARIAHKHASLGVTRDQYALVHQH
                     LFAAIADVLGEAVTPQVAEAWDEVYWLMANALATMEERLTAEQNALAAGTWRPWEVVAR
                     HDDTPEVAVLRLRPADGRPAVPFRAGQYVSVRVELPDGARQIRQYSLTGAFEGDERTIA
                     VKRVPGGPGPEGEVSGHLHARTRAGDLLDLSAPYGDLVLDHTPGADGRPAPVLLASAGI
                     GCTPVVAMLGELAERAHEGRVTVVHGDRTPVTHPLRTLHAELTGRLADAEAHFWYEEPT
                     AGPGALTGRVDLKAVPVAPGTRAYLCGPLPFMRAVREQLLEQGVRPADIHYEVFGPDLW
                     LASADAAA"
     gene            15565..15795
                     /locus_tag="B590_RS08750"
                     /old_locus_tag="B590_08870"
     CDS             15565..15795
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950786.1"
                     /locus_tag="B590_RS08750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08870"
                     /product="hypothetical protein"
                     /protein_id="WP_003950786.1"
                     /transl_table=11
                     /translation="MAGFLDRAKEQAQRGLAQGKQKIDEVQVQRAGADLLKKLGSAYYA
                     EQRRGGDPRATQDALRALEQHIATHGEQGLR"
     gene            15971..16564
                     /locus_tag="B590_RS08755"
                     /old_locus_tag="B590_08875"
     CDS             15971..16564
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414543.1"
                     /locus_tag="B590_RS08755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08875"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_078493266.1"
                     /transl_table=11
                     /translation="MAPPMSADRFLKALKDEGVTVVEVGSWRSHHRNSKGAWGPVNGVM
                     IHHTVTSGSARTVDICRKGYSGLPGPLCHGVITKDGRVHLVGYGRANHAGLGDDDVLAA
                     VIAERASYPPVNEANTDGNARFYGFECENLGDGKDPWTSAQLDTIERVSAAVCRVHGWN
                     QQSVIGHLEWQPGKIDPRGFTMKSMRERIKGRLK"
     gene            16596..17576
                     /locus_tag="B590_RS08760"
                     /old_locus_tag="B590_08880"
     CDS             16596..17576
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893582.1"
                     /locus_tag="B590_RS08760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08880"
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="WP_023417142.1"
                     /sec_met_domain="PALP (E-value: 4.4e-21, bitscore: 74.0,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAHPDPVPPVPEPSVPRARDGRARREPVRPLLPSPVQELREPAF
                     ERYGVRLLLKRDDLIHPDIPGNKWRKLAPVLQAEDGRTVVTFGGAWSNHLRATAAAGRL
                     LGFPTVGVVRGEELAGRPLNPSLARCRADGMRLVFVSRSRYRMRGDVAVRDALVAEAAG
                     PGQPVRVVPEGGSDDAAVRACAVLGEELAALRESVPAVAVACGTGGTLAGLAAGLAPEQ
                     EAVGVAVLKGGFLGAEVAAHQRAAFGGERGRWTVEDGFHHGGFARTSQELEEFAASFEQ
                     RHGLGVERVYVAKLLHGLAALAAEGRFRRGTALAAVVTGRPFPEA"
     gene            complement(17581..19176)
                     /locus_tag="B590_RS08765"
                     /old_locus_tag="B590_08885"
     CDS             complement(17581..19176)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470744.1"
                     /locus_tag="B590_RS08765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08885"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_023417143.1"
                     /transl_table=11
                     /translation="MDVLPLLLLVAGSTAVAGAARRTAVPAPLILVTAGLLVSYIPGVP
                     AYTLDPEIVLPMVLPPLLHTAAMDSSYLDLRAQSRSVALLSVGYTLFATLVVGWAVHLI
                     VPDLPLTAALVLGAVVAPPDAVAATAVARRAGLPSRITTILQGESLVNDATAITAYRVA
                     VAAAIGESAGLLHAGADFLIASLGGVAVGLVLMVPLHWLRTHLREPLFKNTLSLLIPFA
                     AYALAEYAGASGVLAVVVVALYLGHHSWQVDFATRLQEDAVWKMVAFVLESAVFALIGL
                     QLPLVVGGLGDYHVGEVLWYALAVFLVVVATRFVWTYPAVYLPRLASRRIRAREPDPTW
                     KGPFVVAWAGMRGVVSLAIAFSIPHTVHEGGPFPYRNLILFLTFTTVIGTLVVQGLTLP
                     ALIRLLRLPGRDVRAETLLEAQAQNAASEAAERRLDELLADPRNALPQPLADRLRSVLE
                     RRRNAVWERLGTVNPQTGESVDDTYRRLARSMIASEREVFVALRDRRHIDDEMLRALLR
                     RLDLEEAAAYREDG"
     gene            19255..19515
                     /locus_tag="B590_RS08770"
                     /old_locus_tag="B590_08890"
     CDS             19255..19515
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950782.1"
                     /locus_tag="B590_RS08770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08890"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_023417144.1"
                     /transl_table=11
                     /translation="MNKCTHVAELPHPEPAPSADTCLECLAVGSNPVQLRKCLHCGHVA
                     CCDSSPHRHATAHFRESGHPVMRSAEPGESWRWCHADGSIV"
     misc_feature    19584..19597
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.69"
                     /tool="antismash"
     misc_feature    19590..19603
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.89"
                     /tool="antismash"
     gene            19734..20147
                     /locus_tag="B590_RS08775"
                     /old_locus_tag="B590_08895"
     CDS             19734..20147
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="B590_RS08775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B590_08895"
                     /product="hypothetical protein"
                     /protein_id="WP_003950781.1"
                     /transl_table=11
                     /translation="MSPIAGEPGTQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLGCVFRLIDDSLEVTVSAPTTDGKAPERDTFAWTV
                     LSALAGKVDSSVAEDNTVSISLHKQRGAGPGPA"
ORIGIN
        1 cgccgcgatg cagcgcgaag gccgggtcga acgagtcgag gggagagttc tccccgtccg
       61 gttccggcgc gctgtcgctg cgaggattga cgatctccgc tgccacttgg tgacccctta
      121 agtcatgagc gttcgagggt tggccacccc ctggatgggg ggtgggcggg caccgcgtgc
      181 gttccgtgtc cgggcggatg ggcccgcctc cacacggggg aggtcgcacg cgcggacgcg
      241 ccgcacacgc gtcctgagcc ccggatgagg ggtgtaaccg tcttttctac ctgatcgcac
      301 ggacccgtgc cgagccgaat tggccacacg gcccgctcac atgtccgact tcccgggaac
      361 ctcccccggt gcgccatctc tgtcccacat ggcgagatgt gcggtatgcg cgtgacttaa
      421 gtaacggact ccggcggcat ggccgaagcc ctttccgcgc ggggccgttc gggcccgata
      481 gggacccgtt atccgatttt gacatgggcg gcgcctcgtt ctccgcggtc cgaatggcaa
      541 gatgccaccc atcgcacgag gtcgcgacac ccgaaggtgt gtgccaacga cccgtccggc
      601 accctcgcca tccgctcacc tgtcggagga aaccctcatg accgccagca tcacgcgtcg
      661 cccccggccc cttcgctccc gtctcgccgc ggccggcgcg atcacggccg cgggcgccct
      721 cctcctcacc ggctgcggcg accagaccgc gggcgccgac aagggcgggg agaaggagac
      781 cacggccccg ctcgccgaca agctgccgaa gaagtaccag gacagcggtg tcgtcaaggt
      841 cggctcggac atcgcgtacc cgccggtgga gttcaaggac aaggacggca agaccgtcgg
      901 tctggacgtg gacctcgccg ccgcgctcgg ggagcagctc ggggtggagc tgaagttcga
      961 gaacggcacc ttcgacacgc tcctgggcgg cctgcgctcc aagcggtacg acgtggcgat
     1021 gtcggcgatg accgacacca agtcgcgcca ggagggcctg gactccgaga ccggcaagaa
     1081 ggtcggcgag ggcgtcgact tcgtcgacta cttcaccgcc ggcgtctcga tctacaccaa
     1141 caagggcaag gaccagggga tcaagacctg gcaggacctc tgcggcaaga agatcgtcgt
     1201 ccagcgcggc accgtctcgc acgacctggc caaggccgag tcgaagaagt gtgagaaggg
     1261 cgagatcaag atggagacct tcgacaacga ccagcaggcc cagacccggc tgcgctcggg
     1321 cggtgccgac gccggttcct ccgacttccc ggtcgccgcg tacgcggtga agacctcggg
     1381 cggcggcgac cacttcgagc tggtcggcga acaggtcgag gcggcgccgt acggcatcgc
     1441 gatctccaag tccaacccgg aactgcgcga cgcgatcaag gccgcgctgg acgcgatcat
     1501 cgagaacggc gagtacgaca agatcatcaa gaagtggggc gtcgaggacg gcgcggtcac
     1561 cgaggcggtc gtcaacggcg gcaagtgacc cctccggcgt cgctgaaagg caacacctgt
     1621 gtctgctgac atcaccaaga aggacccgga ggccacccct ccgggtccgg cccccacgcg
     1681 ggcggccccc atcaaggccg tcccggtgcg ccactacggc cgctacgtct cggcgctgat
     1741 cgcgctcgcg gcgctcggct cggtcgtgta cgcgttctcc cagggcgaca tcaactgggc
     1801 cttcatcccg gactacttct tcaacgaccg catcctcagc ggcgtccgcg agacgctgat
     1861 cctgaccttc ctgtcgatgg tcatcggcgt ggtcggcggt gtgctgctgg cggtgatgcg
     1921 gctgtcgaag aacccggtgg tctcctcgat cgcctggttc tacatctggt tcttccgggg
     1981 caccccggtc ctggtccagc tcttcgtctg gttcaacctc ggcttcgtct tcgagtacat
     2041 gaacctcggc ccgttctaca aggacgagtg gtcggacttc atgacgccgt tcctgacggc
     2101 gctgctgggc ctcggcctca acgaggccgc gtacatggcg gagatctgcc gggccggtct
     2161 gctctcggtc gacgagggcc agacggaggc ggcccacgcc ctcggcatga gccagggcaa
     2221 gaccctgcgc cgcatcgtgc tgccgcaggc gatgcgcgtc atcgtgccgc ccaccggcaa
     2281 cgaggtcatc aacatgctga agacgacctc cctggtggcg gccgtccagt actacgagtt
     2341 gttcaagcac gcgcaggaca tcggcatgac ctccggtgcc accgtggagg cgctcttcct
     2401 cgccgccacc tggtacctga tcctcacctc gatcctcagc gtcggccagt actacatcga
     2461 gcggtactac gcccgtggtt cgctgcggca gctgccgcag accccctggc agaaggtgcg
     2521 cgcgcacctg acctcgctct ccagccgctc ggaggtgacc cgatgaccgc catggtgaag
     2581 gccgagggcg tccacaagtc cttcggccag gtcgaggtgc tcaagggcat cgacctggag
     2641 gtcgccaccg gagaggtgtt ctgcctcatc ggcccctcgg gctccggcaa gtcgaccttc
     2701 ctgcgctgca tcaaccacct ggagaagatc aacgccggcc ggctctacgt cgacggcgac
     2761 ctggtcggct accggcagaa gggcgacaag ctctacgagc tgaaggacac cgaggtcgcc
     2821 ctgaagcgcc gggacatcgg catggtcttc cagcgcttca acctcttccc gcacaagacg
     2881 gcgctggaga acgtgatgga ggcgcccgtc caggtccggg gcgtctcgaa ggcggcggcc
     2941 cgcgagcggg ccggccagct cctggagcgg gtcggcctct ccgacaaggc gggcaactac
     3001 ccctcgcagc tctccggcgg ccagcagcag cgcgtggcga tcgcccgcgc gctggcgatg
     3061 gacccgaagc tgatgctctt cgacgagccg acctcggcgc tcgacccgga gctggtcggc
     3121 gaggtgctgg acgtgatgcg ccagctcgcc gaggagggca tgacgatgat cgtcgtcacc
     3181 cacgagatgg gcttcgcccg ggaggtcggc gactcgctgg tcttcatgga cggcggcgtg
     3241 gtcgtggagg ccggcgaccc gcgcgaggtc ctgaccaacc cgcagcacga gcggacgcag
     3301 tcgttcctgt cgaaggtgct ctgagtcccg cgaggccggg ccctgcacac gcgcgggggc
     3361 ggtacggaac ctggtgttcc gtaccgcccc cgcggcgttc ccggccgcct tcgcggttac
     3421 ttcagcccga gcaccatggc gtccgagggc gactgccaga ccgtgcgggc ctcggtgaag
     3481 ccggcctcgc gcagggtgcg ggcgtgccac tcggcggggg gagtgtcgcc gtcggcgtgc
     3541 tccccgtaga tctcgaagcg gcgtgcggtc ggcccggcca ggaccgggtc ggcggcggcc
     3601 agctgccacc aggaggccca gtcgacggcg ccctcggcct tggcctcgtc catcctgcgg
     3661 tggcgctgct cgcggtcggc ggcgttgatc cgcggggtgg cggggtcggg catgtggtcg
     3721 gcgttgagga agacgccgcc gtcgcggacg atcccggcga tctggccgta gagcgcggcg
     3781 agcggttcgc tgtgcagcca gtgcagggcg gtggcggtga ggaccgcgtc gtagctgtcg
     3841 tgcgggagca gcgccggcca gtgggggtcc ttgaggtcgg cggtgacgaa ggtgacccgg
     3901 tcgtccccgg cgaaggtgcc ctcggcgatg gtgagcagcg ccgggtccag gtcgacgccg
     3961 gtactctgcg ccttcgggaa cctcttgagg agccggtccg tgatacttcc cgtaccgcag
     4021 gcgaggtcga gcacgcgcgg ctcggagccg gccaccgcct cgaccatgtc gagcatgaca
     4081 cggaagcgtt cctcgcggtc ggggaggtac cactcctgct gctggtccca gctgatctgc
     4141 caggccgccc agtcggcccc cggggtggcg ccggtctgca ccgcacccgc gtcggtggta
     4201 ccggtcggcg ccgtctctgc gtccgtcatc cgaactcctc cgtagcgtaa taccctaaag
     4261 gcggagctag ccattacatc cgcctgcccg accgacccta gaccgagccc gtaaggacta
     4321 caagtggaac tcgcctctta ctcggattac gccctgcgtc tggtcaacag cgaggaaccg
     4381 gcacggggca ccgacacgct cacctccgtg gacgcggtcc gcgccctctt cggagcgagt
     4441 acccaggctg cccgccgggc caccgaggcg gatgtcaccc gtttccgttc ggtacgcggc
     4501 cggctccgcg cggtcttcga ggcggcggcc gggggcgacc agcagcaggc ggtccacctg
     4561 ctcaacgccc tgctcctgga gttcccggtg agcccgcaga tctccggcca cggcgaacgc
     4621 gacgcggagg gccgccccga ctggcatatg cacctcgccg accacccctc caacgccacc
     4681 agcgggtacg ccgccatcgc cgcgatgggg ctggccttcc acctcacgga gttcggcgcc
     4741 gaccgcctcg gcctctgcga ggcgtcgccc tgccgcaacg cctacctcga cacctccacc
     4801 aaccgctccc gccgctactg ctcggaccgg tgcgcgaccc gcgccaacgt cgccgcctac
     4861 cgggcccgca agcgccgcga gagcgacacg tccgagcgga ccgggcgcac cgccgagtag
     4921 gcccagccga gcgtcgcccg catcccgcgc accggctcgc ccccgccacc cgccgtcccg
     4981 cgcggccgca gccgggcggt gacccgggcc agcaccatgg cgcgcggcac cacgccgtac
     5041 accgtgctgt cgccgcccgc gaaggcgttg tcccccagca cccaccagcc gccctcccgg
     5101 cgctccacgg cgcgcttgac gaccagcagg tcctgctgga aggggtggcg caggatgacc
     5161 acgtcacccg ggcggacgcg ggcgccgtac cggaccagga gccagtcgcc gctctccagc
     5221 gtcggcacca tggacggccc gtccacctcc accacgccga accgccccct gccgcgccgc
     5281 tcgtgcgccg ggtcggcagc ccccaccgca cctcgtctga tcgccacctg ctcgcccttc
     5341 cgtccgcctc actcgcctac ccgtccgcgt acccgaggcc acgtccccgg tcccggtctc
     5401 accccgtcct ttcgccctag gcccccgggg gcgaccgaga aaacccgcct cacacggagt
     5461 agtgtcacct gcgagaagac gatcacgagg aaggaccgca cctcatgctt tcccgcctgt
     5521 ttgcccccaa ggtcaaggtc agcgcccact gcgacctgcc ctgcggcgtg tacgacccgg
     5581 cccaggcccg catcgaggcg gagtccgtca aggccgttca ggagaagatg caggccaacg
     5641 acgacccgca gttccagacg cgcgccatcg tcatcaagga gcagcgcgcc gagctggcca
     5701 agcaccacgt ctcggtgctg tggagcgact acttcaagcc cccgcacttc gagagctacc
     5761 cccagctgca ccagctggtc aacgacaccc tgaaggccct ctcggccgcc aagggctcct
     5821 cggacccggc caccggccag aaggccctgg acctcatcgc cgagatcgac cgcatcttct
     5881 gggagaccaa gaaggcttga cccgccggcc cggccccaca ggccgggccc ggccggacag
     5941 accgcacccg gtccacgggg cgccgcacgc cggcgccgct gggccgggtg cggttcttct
     6001 tgcccgcggc ccggccggcc gcacgtagag tcccgccatg atcttgcgga tacgcggtgt
     6061 cgtcctgccg gagcgtgtgg agcggacctt ctggaccgac ggggaggtgc tccgcaccga
     6121 gccgcccgcc gggcccgggg ccgctcgcga ggtggaatcg gtggtggacg ggggctggct
     6181 ggtcccggga ctggtcgacg tgcacacgca tccgggggcc gaggagcccg aggacggttt
     6241 cgacgaggcg gcgctgcggc ggcacctgga ggcgcaccgc gacgcggggg tgctgctggt
     6301 gcgtaccccg gggacgatgg agccaatgcc cggctgggtc gacacggcgc cggagttgcc
     6361 gcgcgtccgg tcggcggggc ggtggctggc gacgcccggg cggttcttcc ccggggtggg
     6421 gcgggacctg agcgaggaac agctgccggg ggccgccgtg gaggaggcca ccgccggttc
     6481 cggctggtgc aagatcatcg gcgactggcg gtgggacgag cccgccgtac ctctggaggt
     6541 catgaccgag gcggtcaccg ccgtgcacgc ggcgggcggc cgggtcgccg tgcactgcca
     6601 gacggccgag ggctcgcgga acgcggtcct cgccggagcc gacagcctcg aacacggcat
     6661 gcatctcgac cccgccctgc tcgacctgat ggcccgccag ggcacggcct acatccccac
     6721 tctgggcgcc ttctccggga gcgccgaggt gtggcgggcc cgggagcgga gcgcgaagcg
     6781 ttcggcctgg ctggaggggt gggccgggat ggtggccaac gtgcgggccg cccacgaggc
     6841 gggcgtcacc gtcctcgccg ggacggacac cttcccctgc ggcaccgtgg ccgccgagtc
     6901 ccggcaactc ctcgacgcgg gcctacccgc cgaagaggcg gtcggcgcgg cctcctgggc
     6961 cgcacgctcg tggctcggcc tgccggggct cgccgacggc gtaccggccg acctggtggc
     7021 gtacggccga gatccggtcg ccctcccgga ggtgctggag cacccggcgc ggatcgtgct
     7081 gcgggggcgg gtggtgcggt agcgcctccg gtgacccgct cggccgggca cttcgtccga
     7141 cgggtgcgat gtcggtccgc ccgtgggcag cgcgccgacg cgctgtcaga cctgatcgag
     7201 ccggagacgc tcgcccacgc cccgtcgaac gggtcaggcc ggctgctcgg ccagtgtctc
     7261 ccggaccagg gccaggacct ccttctcgcc gagcccgagc gagcgggcct cggccaccag
     7321 ggtgcgggcg tgtgggagga gggcggcgcg gctgctgacc gtgccggtgc gggcgaccac
     7381 ggcgcctcgg ccgcggcgga gttcgatcag cccctcgtcg cgcagttgct ggtagccgcg
     7441 gaggacggtg tggacgttga cgcccaggga gtcggcgagg gtgcgggcgg cagggagccg
     7501 gtcgccgggg gcgaagccgc ccgaggcgat ggcggcgcgg gcggcggccg cgacctggtc
     7561 gccgagcggt accggggagc cggggtcgat gtggagcaac atggtcagcg cgtctccggg
     7621 cggcgttcgg ccagcgtgtt gaggagagcg gcggccgtgc ccgcgtcgtc cacggtgacg
     7681 gcgaactccc gcccgtcccc ggtcttgcgc accacgagcg cctcccctga acggttgacc
     7741 agcccggacc gcttcggcat caccggtacc cccagccacc gaactccccc agcggatcga
     7801 ccggccgggc ctgcgcggtg gccactcggt cgagggggac gctcagccgg ggccagtgca
     7861 ggccgcagag gcgcaccgtc aggccgcgct ggcccacgac gacgtcggcc tgggccatca
     7921 ggaccagcag caggccgccc agcagcagga cgatcgcggc ccaccagggc atcgcggaga
     7981 ccgtcagcgg agcgagagca ccgaccatca gcacgacacc gcccagcagc atgggcacgg
     8041 aactggtgcg ccgcgcccac ccggcacgcc cctcgcgggg caggtccagc cgctcggtgc
     8101 cgttctcgcc ccggctcggg ggccagtccg ggaccatcgt cctgaccagg gcgtgcccga
     8161 ggaggccgcc ggcgaggccc acggcgaagg cgacgcccag gtgccacagg ggcaggctga
     8221 ggccggccgc gcgggcggca ccggcattga ggcggagcac caggacggcg atcgtgccga
     8281 ggaaggccgc gaggccccag cccgccgcgg tcgcgacgcc cgtaccgcct ccgccgcccc
     8341 ggccgctcca ggcgaccatc gctgtccagg ccgcgccgcc gagcagcagc atcgcggcca
     8401 tggcgaccag gaactggccg ggagtctcga accggtccgc cgctccgccc ggcccgaagt
     8461 gcacggccag ctcacccggg agccggtcac gcatcccggc gtggacggcc gccacgacag
     8521 ccgtcgtgac gacgaacggc agggcgacga gggcgaccag tcggcgcgga acacggtacg
     8581 gggggccggt ggcggtcatg ggctactcct ccgctggatg cgggcagggc cgtggccaca
     8641 cacgtcccgt ccgggcagga cggcccgacc atgtgcactt gttagcattc aactagaaca
     8701 acaggcggag ggcaagggag ggcagccccc gccggtaccc accccccgtt gtcggtgccg
     8761 tggtgcaggg tcggacaggt cgcggcacag gcagtggaga ggtgaggtgg gcggcatggc
     8821 ggtcgctgga gagcgggtcg cggagcggaa gttcctgcgc gggctctacg aggacccgta
     8881 cttcccggac cgggttctgg accagggggt ggccatcctg accgccctgt gcgagcggat
     8941 cgaggccgag cggccggcgg acctcgcggc cctgtacgtc ctcactgacg ccgccaccga
     9001 ggagttcaac gccctggagg ccgcgttcga ggcggccggc agcgagatcg agacagtggc
     9061 tcgcgaggag atcgccgagg agttctgggt catcgcctcg gcgtacggct tcgcggcggc
     9121 cgaccccgag cggctggtgg gcgcgcggta ctggtgaggt agtggcaaag gaggggcggg
     9181 ccggaatccg gcccgtcacc ccgccgtggg ctcccgccac atgggccaca tcagggggcc
     9241 gtccgggagc cgcagcggct cgccccggtc ggtgaaaccg aggcggaggt acagctcgcg
     9301 gctgcgggcg ctgctggcct ccaggtaggc ggggaggccg tcccggtcgc actgctccag
     9361 tacgggggtg agcagggcgg tgcccagccc ctcgccctgc cggtccgggg cgacggcgat
     9421 cagcagcagg taggcgtggg cgcgctcggt ggggtggatc gcgccggtga ggcggccgac
     9481 gagttcggcg cgctcgttgt cggggtcggc ggtgcgccgc atcagggcgg gcatgtcgtc
     9541 ctcctcctgc tcccccgccg ggacggagag ccagagggcg gcggccgagc cgtcctccag
     9601 gaggtcgacg cgcccagcgg cgagcgccgc gtcgaggaag caccccatga agaggccgtg
     9661 gacagcgcgg cggtgctcct cctcggggaa gacccaactg ctcaccgggt cgtcgtggaa
     9721 ggcggtgtcg agcagggccg ccaccaggtc ccggtcggcg gcctccgccg tacgcgtcgc
     9781 cactcccact gtcgccccct tctccacccg cccgcacgga cggtccggcg cggcccgcac
     9841 ggcccactgc cgcccggtgc gcgcgcctcg gtcactcacc catcggcccg cgccgggagt
     9901 cgagcatcaa ctccctttag gtgcgagccg gttgcagggt agggcatcga gggaaccggc
     9961 gggtgcggat caggcccgcc ggtcccgggt gggcaggagg tcagtaggag cgacgcgtga
    10021 cgaactccgc cagcgagagc agaccgccgg cccgcgccgg atcggggacg gccagggaga
    10081 gctgctgcac ggcgcgcccc atccggtcgg ccgcctcggc ctgcgcccag tcccgcccgc
    10141 cggccgcctc caccagcgcg acggtacggg ccagttcgtc cggctcgggc ggtccggcgt
    10201 accgttccgc cagctcggcc ccggccgccg taccggaggt gagggcggcg accaccggca
    10261 gcgacttctt ccgcgccgtg aggtccgcgc ccgcgggctt gccggtacgc gaggggtcgc
    10321 cccagatgcc gatgatgtcg tcgatgagct ggaaggcgag cccggcctcg cgcccgaagg
    10381 cgtcgagggc gttgacctgg tccggctcgg cgtcggcgtg gagcgcgccg agggcgcagg
    10441 cacagccgag cagggcgccg gtcttggact ccgccatggt gaggcactcg tcgagggaga
    10501 cctcggtggg ggcgcggtcc tccagggcgc agtcggtgtg ctggccggcg cagagttcga
    10561 tcacgcagcg ggtgaggcgg gcgacggcgg ccccggcccg tgggtgcggg tcctcggcca
    10621 gccactgctg ggcgagggac tggagcgcgt ccccggcgag gatcgcgtcg gcgtcgccga
    10681 agacggtcca ggcggtgggc cggtggcgcc gggtgcggtc gcggtcgatg acgtcgtcgt
    10741 ggagcagggt gaagttgtgg gtcagttcga cggcggcggc gctgcgcagg gcgcgctcgg
    10801 gccgtccgcc cagggcgtgc acggcggcga ggaccagcgc cggtcgcacc gccttcccgc
    10861 cgttggcgcc gctggcgagc cctgcggcgt cctcccagcc gaagtggtag cgggcgacgc
    10921 ggcgtatcgg cgccggcagc gtgtcgaccg cgcggcgcag ctcgggcccg accaccgccc
    10981 gcgcctcgtc caggatctcc gcggcctcgt ggctgtcggt tctgctctgc gtgatgtgcg
    11041 tcatgggtgt tcccttctcc ccttttcccc ggtcccgccg tccagctgtc ctgccgtccc
    11101 gctgtccgta cccctccccc ggccgccgca cggcgaccgc ctcacgcccc tccccgcacc
    11161 gcgcacccgg cacccgcccg tcctcagcca cggaggcggc tcacccggga ggcgacgctc
    11221 cgttcctgcc cttgaacgcg tccgggtacg acgacttggc tccggcgccc gggcgacagg
    11281 cccgttcacg cccagctgcg ggccagtcgc acgccgcgga ccggacccgg cctccgggac
    11341 cggcaccgga cagccccgcg cccctgtcgt cccccgcctc cccaccggaa ctcccgtcag
    11401 gcgaccaccg gccggcccct cgttccgctt tcaccttgcg ctcccggaca ccggggcgcc
    11461 cgcccttccg gtgatacccc ggcgaccttc tcgactcccc cgcttcgccc gcacgcgccg
    11521 gcccggcccc gcgccgtacc cggctgccgg accgccgccc gtcacctgcg ccccagcctc
    11581 cgaggcgccg gtgacgggcg gtgcgggcag cgggcgaccc ggggcacgtg cggcatggcg
    11641 cagtagggcg acggggcgtg cttccgccgg gccggggacg aggcggggtg ccggccctca
    11701 gcgggccccc ggggcgtggc caggtcgccg gggagagcgt ctccgtcctc gggcccgccc
    11761 ccgcccggcc gggtgccggg caggagacgg gcgagggtgg tgcagagcag gcgcagcggt
    11821 gcggtgaacg cccaccggcc ggcccgcagc acggtggccc tgaagccgcc gcccgcctgg
    11881 ccggaggtgg cgggctccgc cgtggccccc ggcccgccgc cctgggcgga cggccggccg
    11941 ggcgggccgt ggtgggtgcg gttcatcagc gaccgctcag tgccagcggc cgatttcgac
    12001 gttctccagg acccccaggg cgtccgggac gaggaccgcc gccgagtagt aggtcgtcac
    12061 caggtaggag atgatcgcct gctcgctgat ccccatgaag cggaccgaga ggctgggctc
    12121 gatctcgtcc gggatgccac tctgccgcag gccgatgacg ccctggtcct cctcgcccgt
    12181 acgcatgcag atgatggagc tggtgcgggc ctcggtgacc gggatcttgt tgctcgggaa
    12241 gatcgggacg ccgcgccagg ccgggacgcg gttgccggcg acctccaccg actccgggta
    12301 gatcccccgc ctggtgcact cgcggccgaa ggcggcgatg gcgcgggggt gggcgaggaa
    12361 gagcttcgat ccccggcggc ggctgagcag ttcgtccatg tcgtccgggc cgggcacacc
    12421 ggcgtgcggc tggatccgct ggtcgtactc gcagttgttg agcaggccga actcgcggtt
    12481 gttgatgagt tcgtgctcct ggcgctcctt gagcgcctcg acggtcaggc ggagctggtg
    12541 ctccgtctgg ttcatcggct ggttgtagag gtcggcgacg cggctgtgga tgcgcaggac
    12601 ggtctgggcg acgctcagct cgtactcgcg gggcgaggcc tcgtagtcca cgtaggtgcc
    12661 ggggaggacg gcctcgccga cgtggccggc ggagaggtcg atgggggcct cgccgtactt
    12721 gttggtccgc tgctgcggca gggaacggag ctgccggagg tgggcggcga gcggctcggc
    12781 gcgctcggcg acctgcgcga cctggtcggc ggggaggacc aggacggtgc agtgggtggc
    12841 ggcgcgcgcc gtgtactccc agatggcctc cgggtcggtg agggcctgct cgccgaagta
    12901 cgcgccgtcg gcgaggacgc cgaggacgga gtcgtctccg taggggccgg tgccgatctt
    12961 ctccacgcgg ccgtgggcca ggaggaagac ggcgtcggtg cggctgccga agggggcgag
    13021 tgtctcaccg gcctcgaact cgcgctgctc gcagcgcgag gccagttcgc cgaggacgtc
    13081 ctgctcctgg aactcccgca gcgcgggcag ttcgcccagc tctgcgggga tgacctggac
    13141 gcggtccccg gtcttcacga aggtgacccg gccgtcgccg accgagtagc tgagcctgcg
    13201 gttgacccgg tacgtaccgc cctgcacgtc cacccagggc agcgtgcgca gcagccagcg
    13261 cgagctgatc tcctgcatct gcggcacgga cttggtggtg gtggccagat tccgcgcggc
    13321 ggatgtggcc agactctgct ggggtgtggc ctgctccgcg cggatctctt cgcctaccga
    13381 catgaaattg ccctcccgat caaacactga actcggcgcc cagacttcca tcacccagtg
    13441 gagtcacgcc attacacaaa cgagtgggaa tgatcgactc tccggcgggg cagcttgctg
    13501 tttctttcga acagccccct acgagggcct taagttgcat cacacgtgca agtttttcta
    13561 ggctgcggcc atgcggctca ctcgcttcac cgacctggcg cttcgcgtcc tcatgcggct
    13621 cgccgtcgag aacccgaagg ccaccgccga cctccccacc acccgggagg tcgccgccgg
    13681 gatgcgcgtc ccgtacaccc acaccgccaa ggcggtcgcc cggctccagc acctcggcct
    13741 cgtcgaggcc cgccggggac gcggtggcgg gctcgccctc accacggccg gccgctccgc
    13801 ctccgtcggc gccctggtgc gcgaactgga gggcaccggc gacgtcgtgg agtgcgaggg
    13861 cgccgagccg tgcccgctgc gctccgcctg ccgcctgcgc ggcgccctcc gccaggccca
    13921 ggaagccttc ttcgccaccc tcgacccgct gaccgtcgac ggcctcgcgg cctccccgac
    13981 cggccccgtc ctgctcggca tcgcccgcag ccgggccccc gacgagctct gacgcctccc
    14041 cctcagccgc cctcccggcg acccgccctc cgcgcgccgc agaattggaa tccgagaaac
    14101 caattaagcg gcgccagctc ttcacctcaa cctctcccac ctctccagga gtccccatgc
    14161 tcaccgagcg atcggccgcc accgtccgcg ccaccctgcc cgccgtcggc gcggcgatcg
    14221 gcgagatcag cgggcagttc tacgaccggc tcttcactga ccgcccggag ctgctgcggg
    14281 acctcttcaa ccgcggcaac caggccgccg ggacccagcg gcaggcgctc gccggctcga
    14341 tagccgcctt cgccggccac ctgctcgacc acccggacag tcgccccgac gcgatgctcg
    14401 cccggatcgc ccacaagcac gcctcgctcg gcgtcacccg cgaccagtac gccctggtcc
    14461 accagcacct cttcgccgcc atcgcggacg tgctcggcga ggccgtcacc cctcaggtcg
    14521 ccgaggcgtg ggacgaggtg tactggctga tggccaacgc cctggccacg atggaggaac
    14581 ggctcacggc cgagcagaac gccctggccg ccgggacctg gcgcccctgg gaggtcgtcg
    14641 cccgccacga cgacaccccc gaggtcgccg tcctgcggct gcgccccgcc gacggccgcc
    14701 ccgccgtccc cttccgggca ggccagtacg tctccgtacg ggtcgaactg ccggacggcg
    14761 cccggcagat ccgccagtac tcgctgaccg gcgccttcga gggcgacgag cggaccatcg
    14821 ccgtcaagcg cgtaccgggc ggaccggggc ccgagggcga ggtctccggg cacctgcacg
    14881 cccgcacccg cgccggtgac ctgctggacc tctccgcgcc ctacggcgac ctcgtcctcg
    14941 accacacccc cggcgccgac ggccgcccgg ccccggtcct gctcgcctcc gccggaatcg
    15001 gctgcacccc ggtcgtcgcc atgctcggcg aactggccga aagggcccac gagggccgcg
    15061 tcaccgtcgt gcacggcgac cgcacccccg tcacgcaccc gctgcgcacc ctccacgccg
    15121 agctgaccgg ccggctcgcc gacgccgagg cccacttctg gtacgaggag cccaccgccg
    15181 gccccggcgc gctcaccggc cgggtcgacc tcaaggcggt cccggtggct cccggcaccc
    15241 gcgcctacct ctgcggcccg ctgccgttca tgcgcgccgt ccgcgaacag ctcctggagc
    15301 agggggtgcg cccggcggac atccactacg aggtgttcgg gcccgacctg tggctcgcct
    15361 cggccgacgc ggccgcctga gccgccgtca ccgccccggc gccgtcctgg gacacgccgg
    15421 gcgaaccacc gggaaccacc cgtgtgcgcg gcccgttgag cccgacggaa gccgcgaccg
    15481 gtccacgggg tccgggcggc ggccccgcgc ctcgcggaca ccggggcccc gagcggggca
    15541 cccaggacag aaggagcacg gaccatggct ggattcctcg accgcgccaa ggagcaggcc
    15601 cagcgcggtc tcgcccaggg caagcagaag atcgacgagg tgcaggtgca gcgggccggt
    15661 gccgacctgc tgaagaagct gggctccgcg tactacgccg agcagcgccg gggcggcgac
    15721 ccccgtgcca cccaggacgc cctgcgcgcc ctggagcagc acatcgccac ccacggggag
    15781 caggggctgc gctgacggtc cggcgggtgg gcccgcgcgt gctcgcgggc ccaccggtcg
    15841 gccggatcgc gtcgtacacg cgtctcgtgg caccgcgcgg tcttgacgga ctccgattgc
    15901 gggtacaaag cgatccacac gaggtgcccg cgcaccgggc gggcaccgct tcgcacccga
    15961 aggaggcggc atggccccac ccatgtcagc ggacagattc ctcaaggccc tcaaggacga
    16021 aggggtcacc gtcgtcgagg tgggcagctg gcgcagccac caccgcaaca gcaagggcgc
    16081 ctgggggccc gtcaacggcg tgatgatcca ccacacggtc acctccggca gcgcccgcac
    16141 ggtcgacatc tgtcgtaagg ggtactccgg gctgcccggc ccgctctgcc acggcgtcat
    16201 caccaaggac ggccgggtcc acctggtcgg ctacggcagg gccaaccacg cggggctcgg
    16261 cgacgacgac gtcctggcgg cggtcatcgc cgagcgcgcc agctaccccc cggtcaacga
    16321 ggccaacacc gacggcaacg cccgcttcta cggcttcgag tgcgagaacc tgggcgacgg
    16381 caaggacccc tggaccagcg cccagctcga cacgatcgag agggtctcgg cagccgtctg
    16441 ccgggtccac ggctggaacc agcagtccgt catcggccac ctggagtggc agcccggcaa
    16501 gatagacccc cgcggcttca ccatgaagtc gatgcgcgag cgcatcaagg gccgcctgaa
    16561 gtgaggcgtg cggcggccgg gccgacaatg aaggggtgag cgcccacccc gaccccgtac
    16621 cgcccgtccc ggagccgtcc gtaccccgtg cccgggacgg ccgcgcgcgc cgcgagccgg
    16681 tgcgcccgct gctcccctca ccggtgcagg agctgcgcga gccggccttc gagcggtacg
    16741 gggtgcggct gctgctgaag cgggacgacc tgatccaccc ggacatcccg gggaacaagt
    16801 ggcgcaagct cgcgccggta ctccaggcgg aagacggccg gacggtggtg accttcggcg
    16861 gggcctggtc caaccacctg cgggcgacgg cggcggccgg gcggctcctc ggcttcccga
    16921 ccgtcggcgt cgtccggggc gaggagctgg ccggccgtcc cctcaacccc tcgctcgcgc
    16981 ggtgccgcgc cgacggcatg cggctggtct tcgtcagccg ctcccggtac cggatgaggg
    17041 gcgacgtggc tgtccgggac gcgctggtgg ccgaggccgc cgggcccggg cagccggtgc
    17101 gcgtcgtgcc cgagggcggt tcggacgacg cggcggtccg ggcctgcgcg gtgctcggcg
    17161 aggagctggc cgcgctgcgg gagagcgtgc cggcggttgc cgtcgcctgc ggcaccgggg
    17221 gcaccctggc cggtctggcg gcggggctcg ccccggagca ggaggcggtg ggcgtcgccg
    17281 tgctgaaggg cggcttcctg ggcgcggagg tggcggcgca ccagcgggcg gcgttcggcg
    17341 gtgaacgcgg ccggtggacc gtcgaggacg gcttccacca cggcggtttc gcgcggacca
    17401 gccaggaact ggaggagttc gccgcctcct tcgagcagcg gcacggcctc ggcgtggagc
    17461 gcgtgtacgt cgccaaactc ctgcacggcc tggccgcgct ggcggcggaa ggccgcttcc
    17521 gccggggcac ggcgctggcg gcggtggtca ccggccgccc gttccccgag gcgtagcgga
    17581 tcagccgtcc tcccggtagg ccgccgcctc ctccagatcg aggcggcgca gcagggcgcg
    17641 gagcatctcg tcgtcgatgt ggcgccggtc gcgcagggcg acgaagacct cccgttcgga
    17701 ggcgatcatg gagcgggcca gccgccggta ggtgtcgtcg acgctctcgc cggtctgcgg
    17761 gttgaccgtg cccagccgct cccagaccgc gttgcggcgg cgctccagca cggaccggag
    17821 ccggtcggcg agcggctggg gcagggcgtt gcgcgggtcg gcgaggagct cgtcgaggcg
    17881 gcgctcggcg gcctcggagg cggcgttctg ggcctgggcc tccagcaggg tctccgcgcg
    17941 gacgtcgcgg ccgggcaggc ggagcagccg gatgagggcg ggcagggtga ggccctgcac
    18001 gacgagggtg ccgatgacgg tggtgaaggt caggaagagg atcaggttcc ggtacgggaa
    18061 ggggccgccc tcgtggaccg tgtgcgggat cgagaaggcg atggcgagcg agacgacgcc
    18121 gcgcatcccg gcccaggcga cgacgaaggg gcccttccag gtggggtcgg gttcgcgggc
    18181 gcggatgcgg cgggaggcga gccggggcag gtagacggcc gggtaggtcc agacgaaccg
    18241 ggtggcgacc accaccagga agaccgcgag ggcgtaccag aggacctcac ccacgtggta
    18301 gtcgccgagg ccgccgacga ccagcggcaa ctggaggccg atcagcgcga agaccgccga
    18361 ctccaggacg aaggcgacca tcttccagac ggcgtcctcc tggagccggg tggcgaagtc
    18421 gacctgccag gagtggtggc cgaggtagag ggcgacgacc accacggcga gcaccccgga
    18481 ggcgccggcg tactcggcca gcgcgtaggc ggcgaacggg atgagcagcg agagggtgtt
    18541 cttgaacagg ggttcacgca ggtgggtgcg gagccagtgg agcggcacca tgaggaccag
    18601 gccgacggcg acgccgccga gcgaggcgat gaggaaatcg gccccggcgt gcagcagtcc
    18661 ggcgctctcg ccgatcgccg cggcgacggc gacccggtag gcggtgatgg cggtggcgtc
    18721 gttcaccagg gactcgccct ggaggatcgt ggtgatccgc gagggcagcc cggcccgccg
    18781 ggcgacggcg gtggcggcga ccgcgtccgg cggcgcgaca acggcgccga ggaccagggc
    18841 ggcggtgagc ggcaggtccg gcacgatcag gtggacggcc cagccgacga cgagcgtcgc
    18901 gaagagcgtg tagccgaccg agagcagcgc gacggaacgc gactgggccc gcagatccag
    18961 gtaggagctg tccatggcgg ccgtgtggag cagcggcggc agcaccatcg gcagcacgat
    19021 ctccgggtcg agcgtgtacg cgggcacgcc cgggatgtac gacacgagca gaccggcggt
    19081 gaccaggatc agcggtgcgg ggacggccgt gcgccgggcc gctcccgcga cggcggtgct
    19141 gcccgcgacc aggagcagca gcggcagtac gtccatggcg ggtggtcccg tccttcccgg
    19201 cgtcgggcgg cagaccatga caggagccac agaagccgcg ttaacctgcc catcatgaac
    19261 aaatgcaccc atgtcgccga gctgccgcac cccgagcccg ccccgtcggc ggacacctgc
    19321 ctggagtgcc tggcggtcgg gagcaacccg gtccaactgc ggaagtgcct gcactgcggc
    19381 catgtggcgt gctgcgactc ctcgcctcac cggcacgcga cggcccactt ccgcgagagc
    19441 ggccacccgg tgatgcgcag cgcggagccg ggcgagtcgt ggcgctggtg ccacgcggac
    19501 ggttcgatcg tctgagcgct gggtacgtca acccggcgcc cggactttcc aattgggctc
    19561 cgcagacccc tagccaccct gtgtataagt atgcttacta tgagtgaggc acaggggcgg
    19621 ggggcctggg acacggacct cgacggcgcg gtagcgtcac ggctggaacg tggcgcgtcc
    19681 cggggactcc tccccggagc cccgaaagtg cttgtaccac cttggaggtg agggtgtccc
    19741 ctatcgcagg cgagcccggg acccaggact tcgtggaagt ccggctgccg gcagcgggtg
    19801 cctacctgtc ggtgctgcgg acggccacgg ccggcctcgc ggcgcgtttg gacttcaccc
    19861 tcgacgagat cgaggacctg cgcatcgccg tcgacgaggc gtgcgcgatt ctgctccagc
    19921 aggccgtgcc gggctcagtc ctcggctgcg tcttccggct gatcgacgac tcactggagg
    19981 tgacggtgtc ggcacccacc accgacggca aggcccccga gcgggacacg ttcgcctgga
    20041 cggtgctctc cgcgctcgcg ggcaaggtcg actcctcggt cgccgaggac aacaccgtct
    20101 cgatcagcct gcacaagcaa cgcggcgcgg gccccggtcc ggcgtgaggg acggggaacc
    20161 ggtgcctgag gagacgcaca gcacctggag tccccccgcg accggcggcg gggaccgacc
    20221 ggccgccggt cctgctgctg ccccggggaa cctcccgggg cagcagcagg cccggcagca
    20281 ccccgagggc gtggagcggc caccggcccg cgccccgggc gggaaggacg gacgggctgc
    20341 gcacggcccc tgggatgtcg cggagcaggc gggaccaatg accgaggaca agcaccagga
    20401 cgagaagccg gacgggcagg acgagcagcc ggagcaccag aaggaccagg cgcccccggc
    20461 gggcgccccc gtggaccgcc ccgacccgca cgaccgcagc ggcgcccgcg ccctcttcat
    20521 cgagctgcgc accctgccgg ccggcggccc cgagtacgcg gagcttcgca accggctggt
    20581 ccggatgcac ctgccgctgg tcgagcacct ggcccgccgc ttccgcaacc gcggcgagcc
    20641 gctcgacgac ctgacccagg tggcgacgat cggcctgatc aagtcggtcg accgcttcga
    20701 cccggagcgc ggcgtggagt tctccaccta cgccacgccg acggtggtcg gcgagatcaa
    20761 gcggcacttc cgcgacaagg ggtgggcggt gcgggtgccg cgccgcctcc aggagctgcg
    20821 gctctcgctc acctcggcca ccgccgagct ctcccagcgg cacgggcgct cgccgaccgt
    20881 gcacgaactg gccgagaagc tgggcatctc cgaggaggag gtgctggagg gcctggagtc
    20941 ggccaacgcc tactcgacgc tctccctgga cgtccccgac accgacgacg agtccccggc
    21001 cgtcgccgac acgctcggct cggaggacga ggcgctggag ggcg
//
