LOCUS       NZ_CP106650            20975 bp    DNA     linear   CON 16-MAY-2024
DEFINITION  Streptomyces sp. GBA 94-10 4N24 strain GBA 94-10 chromosome,
            complete genome.
ACCESSION   NZ_CP106650
VERSION     NZ_CP106650.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. GBA 94-10 4N24
  ORGANISM  Streptomyces sp. GBA 94-10 4N24
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7025021)
  AUTHORS   Ian,E., Malko,D.B., Sekurova,O.N., Bredholt,H., Ruckert,C.,
            Borisova,M.E., Albersmeier,A., Kalinowski,J., Gelfand,M.S. and
            Zotchev,S.B.
  TITLE     Genomics of sponge-associated Streptomyces spp. closely related to
            Streptomyces albus J1074: insights into marine adaptation and
            secondary metabolite biosynthesis potential
  JOURNAL   PLoS One 9 (5), e96719 (2014)
   PUBMED   24819608
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7025021)
  AUTHORS   Ruckert,C., Busche,T. and Kalinowski,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-SEP-2022) CeBiTec, Uni Bielefeld, Sequenz 1, Bielefeld
            33615, Germany
REFERENCE   3  (bases 1 to 7025021)
  AUTHORS   Ian,E., Sekurova,O.N., Malko,D.B., Ruckert,C., Borisova,M.E.,
            Albersmeier,A., Kalinowski,J., Gelfand,M.S. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAY-2013) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-NOV-2021
            Assembly Method                   :: flye v. 2.9-b1768
            Assembly Name                     :: GB94_v2
            Genome Coverage                   :: 229.4x
            Sequencing Technology :: Illumina MiSeq;Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000495635.2-RS_2024_05_16
            Annotation Date                   :: 05/16/2024 06:31:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,298
            CDSs (total)                      :: 6,204
            Genes (coding)                    :: 5,988
            CDSs (with protein)               :: 5,988
            Genes (RNA)                       :: 94
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 216
            CDSs (without protein)            :: 216
            Pseudo Genes (ambiguous residues) :: 0 of 216
            Pseudo Genes (frameshifted)       :: 100 of 216
            Pseudo Genes (incomplete)         :: 164 of 216
            Pseudo Genes (internal stop)      :: 24 of 216
            Pseudo Genes (multiple problems)  :: 67 of 216
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:13:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2082089
            Orig. end                         :: 2103064
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP106650.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Wittmann Lab, Saarland
            University, Germany.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20975
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="12"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20975
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20975
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10975](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10975)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    559..574
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
     misc_feature    584..599
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.28"
                     /tool="antismash"
     gene            757..1545
                     /locus_tag="B591_RS08810"
                     /old_locus_tag="B591_08810"
     CDS             757..1545
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950769.1"
                     /locus_tag="B591_RS08810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08810"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_003950769.1"
                     /transl_table=11
                     /translation="MTTDAGGTRTRTADEPATEPTSPVRATRVPKYYRLKRHLLDMTRT
                     LPPGTSVPPERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLT
                     SYTEDMRAQGLEPTSQLLEVGYITADDSLASLLDITAGGRVLRIERLRLASGEPMAIET
                     THLSAKRFPALRRSLVKYTSLYTALYEVYGVRPAEAEETIETSLATPREAALLATDVGL
                     PMLMLSRHSRDESGAPVEWVRSVYRGDRYKFLARLKRPVE"
     misc_feature    1723..1738
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.57"
                     /tool="antismash"
     gene            2045..4267
                     /locus_tag="B591_RS08815"
                     /old_locus_tag="B591_08815"
     CDS             2045..4267
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1185: carbon
                     starvation protein A"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642402.1"
                     /locus_tag="B591_RS08815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08815"
                     /product="carbon starvation CstA family protein"
                     /protein_id="WP_023421737.1"
                     /transl_table=11
                     /translation="MAEPAPPASGNRKLSAKSIAVWSLVAVVGAIAWSVLALSRGEEIS
                     AIWMLAAALGSYAIAYRFYSRFIANKVLKVDKNRATPAERLDNGVDFQPTDRRVLFGHH
                     FAAIAGAGPLVGPILAAQMGYLPGTIWIVAGVIFAGAVQDMVTLFFSTRRNGRSLGQMA
                     RDEIGPVGGVAALVAVFMIMIILLAVLALVIVNALAGSPWGVFSIGMTIPIALFMGVYL
                     RTLRPGKVTEVSVLGVALLLLAIVGGGWVAESSMADFFTLEPGTLVIWMVVYGFFASVL
                     PVWMLLAPRDYLSTFMKVGTIVLMAVCVIIAMPTLKMDGVTSFATSGAGPVFSGSLFPF
                     VFITIACGALSGFHSLVSSGTTPKMVQKETQIRMIGYGAMLTESFVAIMAMIAACIIDP
                     GLYFAINSPAGVLGDTVQSASEAVAGLGFTISPDQLAQAAKDVEEASLLSRTGGAPTFA
                     LGMAEIFAAALGGAGMKAFWYHFAIMFEALFILTTVDAGTRVGRFMLQDTLGNVWKPMR
                     RVSWWPGVWLTSAIVVGCWGYFLWVGVHDPLGGINQLFPLFGIANQLLAAVALAVCTTL
                     LIKSGRLKWAWVTGIPLAWDVAVTLTASWQKIFSDNPAIGFFAQRAKYQDGIDAGEVLA
                     PAKSMSDMHTVVTNSTVDGVLSIVFAVLIIIVLVDAGRVSYNAIRRPESAKLAEAPFEQ
                     SKIVAPAGMFATAEEKAELALVGAGAPASAGDGDGDAPAKQGGDKA"
     gene            4264..4506
                     /locus_tag="B591_RS08820"
                     /old_locus_tag="B591_08820"
     CDS             4264..4506
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642403.1"
                     /locus_tag="B591_RS08820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08820"
                     /product="YbdD/YjiX family protein"
                     /protein_id="WP_023421738.1"
                     /transl_table=11
                     /translation="MSGEAAHHPGRLGVLAHRVRAGARWIGWYVREVSGETAYEKYAAH
                     VRSHDPDAEVMTRRQFERSRMDAREADPRDGFRCC"
     misc_feature    4818..4832
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.01"
                     /tool="antismash"
     misc_feature    4849..4863
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    4857..4870
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     regulatory      4885..4961
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            5124..7499
                     /locus_tag="B591_RS08825"
                     /old_locus_tag="B591_08825"
     CDS             5124..7499
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966408.1"
                     /locus_tag="B591_RS08825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08825"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_023421739.1"
                     /transl_table=11
                     /translation="MTIAPADPSTAEVRAEEIQGPGGALLRTLTDLTADLPDTDPGRVA
                     AAALRGRNAASDEAELRSLATEAAAGLISEDPAYSRLAARLLTRTIAEEAAGQGVTTFT
                     GSVATGHREGLIADRTAAFVTAHAERLDALVDPAADDRFGYFGLRTVHSRYLLRHPHTR
                     QVIETPQHFMLRVACGLAEDDSVRALDEVASLYRLMSALSYLPSSPTLFNSGTRHPQMS
                     SCYLLDSPKDELESIYDRYHQVARLSKHAGGIGLAYSRIRARGSLIRGTNGHSNGIVPF
                     LNTLDASVAAVNQGGRRKGAAAVYLETWHADIEEFLELRDNTGEDARRTHNLNLAHWIP
                     DEFMRRVDADADWSLFSPSDVPELTDLWGDAFDAAYRAAEAQGLAKRTIPARELYGRMM
                     RTLAQTGNGWMTFKDASNRTANQTALPGHTVHSSNLCTEILEVTDDGETAVCNLGSVNL
                     GAFVDGGAIDWERLDEAVRTAVVFLDRVVDINFYPTEQAERSNSRWRPVGLGAMGLQDV
                     FFQLRLPFDSPEARELSTRIAERIMLTAYETSCDLAEKNGPLPHWDRTRTAQGVLHPDH
                     YDTGLAWPERWEALRARVARSGMRNALLLAIAPTATIASIAGVYECIEPQVSNLFKRET
                     LSGEFLQVNSYLVEDLKRLGVWDTRTREALREASGSVQGFAWIPEELRALYRTAWELPQ
                     RGLIDMAAARTPFLDQSQSLNLFMETPTIGKLSSMYAYAWKKGLKTTYYLRSRPATRIA
                     RAAGSSAPATATVPAQAAPDAEAVACSLENPESCEACQ"
     gene            7595..8551
                     /locus_tag="B591_RS08830"
                     /old_locus_tag="B591_08830"
     CDS             7595..8551
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947116.1"
                     /locus_tag="B591_RS08830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08830"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_234025436.1"
                     /transl_table=11
                     /translation="MRYPDFYERYRDAIKNTWTVEEVDLHSDVADLAKLSPGEQHLIGR
                     LVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEEAVHVQFYLTLLDTYLPDPA
                     DRADAFAAVENIPSIREKAEFCFRWMDSVDKLDQLESQADRRKFLLNLICFAACIEGLF
                     FYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFDVVDTVRKEEPELFDDKLQE
                     QVVAMLKEAVEAELQFARDLCGDGLPGMNTESMREYLECVADQRLTRLGFAPVYGSQNP
                     FSFMELQGVQELTNFFERRVSAYQVAVEGTVSFDDDF"
     gene            complement(8637..10004)
                     /locus_tag="B591_RS08835"
                     /old_locus_tag="B591_08835"
     CDS             complement(8637..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950763.1"
                     /locus_tag="B591_RS08835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08835"
                     /product="cytochrome P450"
                     /protein_id="WP_023421740.1"
                     /sec_met_domain="p450 (E-value: 9.4e-78, bitscore: 260.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAESTTERAAAPDPRTPPLVAGSVPVLGHAPSLVRDPLAFLTGL
                     RDHGDLVRVKLGPKTAYAVCAPGLVGALLRNSQEFQVGGPLWENLEVLLGKGVATSNGA
                     DHRRQRRMMQPAFRPERIASYATVMEQEARAMADRWRDGQVVDIGAETFSCAVRVVARS
                     LLEVDSIGAKADRISASLHTVFSGLYRRMILSFGPLHRLPTPANRRFERALADLHHLVD
                     EVIAERHAQGKGADDLLDILLTSEDGEGRPLSDQEIHDHLVSLIVAGAENVASTLAWCF
                     QLLTEHPAEEQRVAEEALSVATDRPVNFGDLGSLDHTRNVIVESMRIRPAAWIFTRRAV
                     TDTELGGYRIPAGADIIYSAYAMQHDPRSFDRPDVFDPDRWIPERAEKVPQYAMMPFST
                     GNRKCPGDHFSMVEATLMLATVLPRWRLVPVPETDPAPRIGITLQPKRAVFRVESR"
     gene            complement(10001..10975)
                     /locus_tag="B591_RS08840"
                     /old_locus_tag="B591_08840"
     CDS             complement(10001..10975)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470738.1"
                     /locus_tag="B591_RS08840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08840"
                     /product="terpene synthase family protein"
                     /protein_id="WP_023417159.1"
                     /sec_met_domain="T1TS (E-value: 1.6e-50, bitscore: 171.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESRAWLLEKRLMPADKVTRYADELRYTDLIAGYYVGAPRDVISA
                     ISDFSTWFFVWDDQHDRDAVHGRRTAWYRLSAELHTALDAPGDHLAHPEPLVAAFAETV
                     HRLNGFLSPAWNERFARHFHAIVGAYDQEFENRVTKVTPQVAEYIELRRHTFGHSVWID
                     LLEPTAGREIPAALRTSGPFLSAARHCQDFSAWYNDLCSLPKELAGDDQHNLGISLIRH
                     EGLSLEEAVTEVRSRVENCVTEFEVAEKELRELLAGHLAALPEGAGSTEARSVAEAVGS
                     AVFNMRNWFSSVYWFHHESGRYRVDSWDDRSTPPYVSDLAGDA"
     misc_feature    complement(11011..11024)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.14"
                     /tool="antismash"
     misc_feature    11011..11024
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.17"
                     /tool="antismash"
     misc_feature    11257..11271
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.73"
                     /tool="antismash"
     gene            complement(11363..12019)
                     /gene="def"
                     /locus_tag="B591_RS08845"
                     /old_locus_tag="B591_08845"
     CDS             complement(11363..12019)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="B591_RS08845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08845"
                     /product="peptide deformylase"
                     /protein_id="WP_023421741.1"
                     /transl_table=11
                     /translation="MAQQDTEQQAVAGGVLAVDDEGFVIDTEDTEEREAAYRARGTARP
                     VTVVGNPVLHRETKDVTVFDAELAQLVDDMFASQRAAEGVGLAANQIGVDKKVFVYDCP
                     DDEGVRHVGVVCNPVLDELPSERRVLDDSNEGCLSVPTAYAALARPDYAVVRGQDEKGN
                     PIVVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAEGTPRYETVPND"
     gene            complement(12112..13104)
                     /locus_tag="B591_RS08850"
                     /old_locus_tag="B591_08850"
     CDS             complement(12112..13104)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415712.1"
                     /locus_tag="B591_RS08850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08850"
                     /product="hypothetical protein"
                     /protein_id="WP_008415712.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARTAGLRAVALLDRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKIPGDAAASGEPSGMGLGSAAVRISPEGEAEVVWGRRLDPARIEVQSIPL
                     PSSGRRWGEVILHDGVPHGERTTASGDTYPVFDEIELWAPSPVPTWVVLLEAQAPADRD
                     ALELLAADAGFAAEDWSSSVRLLCRTCSESRMPSDEGGGERHVDPHDHSEPGQPGPLGH
                     RTTSGEGDLWVPERECGIAAPPALVRGLLDGWVADSPDTRAWRDLEEVC"
     gene            complement(13339..13647)
                     /gene="rsrA"
                     /locus_tag="B591_RS08855"
                     /old_locus_tag="B591_08855"
     CDS             complement(13339..13647)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642406.1"
                     /locus_tag="B591_RS08855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08855"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_003950759.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEVLDHLYEFLDHEMPDSDSNKIRTHFDECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPADLRDKVISRLDMIRAGQAVPQHDIVPTEVADTP"
     gene            complement(13644..14318)
                     /locus_tag="B591_RS08860"
                     /old_locus_tag="B591_08860"
     CDS             complement(13644..14318)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="B591_RS08860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08860"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_026048295.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGSQDVPEKPEETSAERTARFERDALAFLDQMYSAAL
                     RMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKKQREPQRS
                     AAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKSALQAIPEEFRIAVYLADVEG
                     FAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGSGASAAEPNERKGA
                     GS"
     misc_feature    14510..14524
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            complement(14655..15341)
                     /locus_tag="B591_RS08865"
                     /old_locus_tag="B591_08865"
     CDS             complement(14655..15341)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415707.1"
                     /locus_tag="B591_RS08865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08865"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_234025340.1"
                     /transl_table=11
                     /translation="MNVSRSEGVAVPAVPGAGERVSVVTAAGEARVTWVRARAPRIVLA
                     LGHGAGGGVEARDLVALAGALPGAGVSVALVEQPWRVAGKKVAPAPKTLDKGWEAVWDE
                     VAGEGLPVVAGGRSAGARVACRAGAKLGAAGVLALSFPLHPPGKPERSRAEELLGTGVP
                     TLVVQGGRDPFGRPEEFPGGSYELAEVPYGDHGFAVPKKAPVGQEEALGVITDAVGAWL
                     ERLPVG"
     gene            complement(15478..16350)
                     /locus_tag="B591_RS08870"
                     /old_locus_tag="B591_08870"
     CDS             complement(15478..16350)
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="B591_RS08870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08870"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_023421742.1"
                     /transl_table=11
                     /translation="MCGRYAATRSPEDLSEIFGVEKTELSEAADGQEDGHEAGATPAPT
                     ETLVPDWNVAPTKEVPAILDRPVKGSDDPRPVRQLRTLTWGLVPSWATSPDGGARMINA
                     RAETVHEKPAYRRAFASRRCILPADGYYEWVTAPEERKLEEEGKRKRVRKQPYFVTPAD
                     GSVFAMAGLYEFWRDPSLPGDHPRAWWVTCSVITTEAETAPLGVGPEEGPRALADIHPR
                     MPLMLTPDKWDAWLDPSKTDVEEVRELLAAPAEGLMRAYPVATAVSNVRNNGPGLVSEL
                     DGPEVGTLF"
     gene            16440..17162
                     /locus_tag="B591_RS08875"
                     /old_locus_tag="B591_08875"
     CDS             16440..17162
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950755.1"
                     /locus_tag="B591_RS08875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08875"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_023417164.1"
                     /transl_table=11
                     /translation="MQSTTAAPATDLWDRVTGTQTAPEFWLVVATGVAALAVVLWGPAW
                     RPARNAITIAHEGGHGLIALVTGRTLEGIRLHSDTSGLTVSRGRPTGPGMILTALAGYT
                     APSLLGLGGAWLLAAGHITLLLWVATALLLALLVMVRNAYGVLTVLITGGLFVAVSWLA
                     GSEVQALFAYAAVWFLLLGGVRPVFELQSKRRRGGAPDSDADQLARLTHAPAAIWLFLF
                     HAVALCSLIGGGGWLLGR"
     gene            17205..18557
                     /gene="aroA"
                     /locus_tag="B591_RS08880"
                     /old_locus_tag="B591_08880"
     CDS             17205..18557
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642411.1"
                     /locus_tag="B591_RS08880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08880"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_023421743.1"
                     /transl_table=11
                     /translation="MTLNPVSTPLWPAPYATGAVEATVQVPGSKSVTNRALVLAALAAE
                     PGWLRRPLRSRDTVLMAEALRTLGVGIEETVSSDSAAPGSTLAGGGEAWRIIPSGLRGP
                     ATVDVGNAGTVMRFLPPLATLADGDIRFDGDPRSYERPLHGVIDALRALGARIDDDDRG
                     SLPMTVHGTGSLDGGTVEIDASSSSQFVSALLLSAPRFNQGVEVRHIGPRLPSMPHIRM
                     TVDMLRRVGAQVDEPESGGEPNVWRVTPGALLGRDLTVEPDLSNAQPFLAAALVTGGRV
                     VVPDWPAHTTQPGDRLREIFTTMGGSCELTEAGLVFTGSGRVHGIDVDLGEVGELTPGI
                     AAVAALADGESVLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLRIRPRPLHGGV
                     FHTYDDHRMATAGAILGLVVKDVEIENVATTAKTLPDFPDLWTGMLDGTGQ"
     gene            18575..19591
                     /gene="rsgA"
                     /locus_tag="B591_RS08885"
                     /old_locus_tag="B591_08885"
     CDS             18575..19591
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966421.1"
                     /locus_tag="B591_RS08885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08885"
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="WP_023417166.1"
                     /transl_table=11
                     /translation="MRRYGKNPDEDDIRVRPSRRGSRPRTHTRPKHEDAAEGMVLTVDR
                     GRITCLVEGRTVTAMKARELGRKAAVVGDRVALVGDLSGQKDTLARIVRIGERASVLRR
                     TADDDDPYERVVVANADRLAVVTALADPEPRPRMIDRCLVAAYDGGLEPVLVLTKSDLA
                     SPDSLLDTYRALGVPYVVTSREELEDGSAVQRVRELLDGHVTAFVGHSGVGKTTLVNAL
                     VPEEQRRVTGHVNAVTGRGRHTTVSALALPLADAAPGSWVIDTPGVRSFGLHHVDPSRV
                     IHAFPDLEPGTEQCPRGCSHDEAECALDQWVADGHADPARLNSLRRLLATRERREGD"
     gene            19719..20042
                     /locus_tag="B591_RS08890"
                     /old_locus_tag="B591_08890"
     CDS             19719..20042
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950752.1"
                     /locus_tag="B591_RS08890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08890"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_003950752.1"
                     /transl_table=11
                     /translation="MAWLLVVVAGLLETGFAVCLKLSHGFTRLWPTIAFAAFALGSFGL
                     LTLALKRLDVGPAYAVWTGIGAAGTATYGMIFLGDVVSVLKIVSITLVICGVIGLQLSG
                     SAQ"
     gene            complement(20008..20631)
                     /locus_tag="B591_RS08895"
                     /old_locus_tag="B591_08895"
     CDS             complement(20008..20631)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893589.1"
                     /locus_tag="B591_RS08895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B591_08895"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_023421744.1"
                     /transl_table=11
                     /translation="MPEVRAALLIAAEAHLARRPWSAVRMGEVAASAGVSRQTLYNEFG
                     SKEGLARALARQAADGYLAGIERALARPATDPRERLRAAADWTVAAARPGTLLRSLLTG
                     CWGDPLPAPRPARATATAPAAQRRAELPLPGPGDLLAAARDRAVAALDESARPRTDPRE
                     LARECECVLRLALSRIVAPPVVGGAGAGRRRGRVTGPSRRAGGR"
ORIGIN
        1 ttgtagaccg cgacgcgggc accggcgtag tagggcacgc agtactgctt gccctcgaag
       61 gtgcaggtgt cggtgaggcc ctggatccag gtgtccgagt tctcgtactt cttggggtcg
      121 atctcggcga gggcgccgtt gaggatgtac tgcatcgtct cggtgttgcc gagctcgacg
      181 acgtccggga acttgtcccc gccgagggcg gtgtcgagct tcttggcctt gtcggcccag
      241 ccctggtact ggacgttcac cttgacgttg gggtacttct tcttgaactg cgcgttgacg
      301 tccttgacca gctccggcca ggtgctctgg gcgtcgacca tcagccagac ggtcaggtct
      361 tccttgcggt cctcgggctt ggcgttgctc gccgtctccg agtccccgca cgccgcgaga
      421 ccggccatca tgccagcgac accgatggcc gcaatgagct tgcgcttcac gtcaccctcc
      481 tcagggaacc ctctaccccc cacccgcagc gatgacatcg aagacgagtt actgccgtgg
      541 gactgggatc tggtctttaa tggtgtagac cagtaagccg gagcttggcc tagaccttta
      601 ggggtgtcaa gggtgtataa gaagggcagt cacgtccgtt atcggaccga cacctgaggg
      661 agtccggacc ggcgatcacc ggccgtgcca cgatgtgatc cgcgacagac ggaggagccg
      721 gtgacggcag cagcacagga gccggagagg cggagcatga cgacggacgc gggcggtacg
      781 aggacccgga cggccgacga gcccgccacc gagccgacca gtccggtccg ggccacacgg
      841 gtgcccaagt actaccgtct caagcggcac ttgctcgaca tgacgcggac actgccgccg
      901 ggcacctccg tgccccccga gcgtacgctc gccgccgagt tcgacacctc gcggaccacg
      961 gtgcgccagg cgctccagga gctggtggtc gagggccggc tcgaacgcat ccagggcaag
     1021 ggcaccttcg tcgccaagcc caaggtctcc caggcgctcc agctgacctc ctacaccgag
     1081 gacatgcgcg cccagggcct ggagcccacc tcgcagctgc tggaggtcgg ctacatcacc
     1141 gccgacgact ccctcgcctc cctgctcgac atcaccgccg gcggccgggt gctgcgcatc
     1201 gagcggctcc ggctggccag cggcgagccg atggcgatcg agaccaccca cctctccgcc
     1261 aagcgcttcc ccgccctgcg ccgctccctg gtcaagtaca cctctctcta cacggcgctc
     1321 tacgaggtct acggggtgcg cccggccgag gccgaggaga ccatcgagac ctcgctcgcc
     1381 accccgcgcg aggcggccct gctcgccacc gacgtgggcc tgccgatgct catgctctcc
     1441 cgccactccc gcgacgagag cggcgcgccg gtggagtggg tgcgctcggt ctaccgcggc
     1501 gaccggtaca agttcctggc ccgcctgaag cggccggtgg aataggaccg gcgcacggag
     1561 gacagcgggg cggcacctct caccgggggt gccgcccttt cccatgtccg gcacacgggc
     1621 cggcgggtga caccgggtca ctcgccggga gccgaagccc gtgttccggc cacccggcaa
     1681 cgaccccact cgcccccgcc tgacccccgc cgggccgttc gctcgcatgt gtgtgctttt
     1741 ccgcgcatga ccgccgggcg gtgcggggta cacaccccac cggcgggagg tcacggttgg
     1801 ggggtgatcg gtggggggcc gcccgggcgg ggcgttcacc ccgaggggga caaatacgcg
     1861 gggaggcgtg cgtaaggggc ggggatgcga cggtcgcggc gcgtggttgc gccggacggg
     1921 aagtcgttgc cgttccgata cgcggacagg ggctgtcaaa gcctggaccc gtcgcctaca
     1981 tttccgacgc attgcaggag ttcagcgcag gtgtttccgc cagcgctcat gtgaggggac
     2041 catcatggcc gagccggctc cacccgcctc cggaaaccgg aagctgtccg ccaagtccat
     2101 cgccgtctgg tcgctggtcg ccgtcgtcgg cgccatcgcc tggagcgtgc tggcgctctc
     2161 ccggggcgag gagatctccg ccatctggat gctggcggcg gccctcggct cgtacgccat
     2221 cgcgtaccgc ttctactcgc ggttcatcgc caacaaggtc ctgaaggtcg acaagaaccg
     2281 ggccaccccg gcggagcgcc tggacaacgg tgtcgatttc cagccgaccg accgccgggt
     2341 gctcttcgga caccacttcg cggcgatcgc gggtgcgggc ccgctggtcg gcccgatcct
     2401 ggcggcccag atgggctacc tgccgggcac catctggatc gtggccggcg tgatcttcgc
     2461 cggggccgtc caggacatgg tcaccctctt cttctccacc cggcgcaacg gccgttcgct
     2521 cggccagatg gcccgggacg agatcggccc ggtcggcggt gtcgccgccc tggtcgcggt
     2581 cttcatgatc atgatcatcc tgctggcggt gctggccctc gtcatcgtca acgcgctggc
     2641 cggctcgccg tggggtgtct tctccatcgg catgaccatc ccgatcgccc tcttcatggg
     2701 cgtctacctg cgcacgctgc gccccggcaa ggtcaccgag gtctccgtcc tcggcgtcgc
     2761 cctgctgctg ctggcgatcg tgggcggcgg ctgggtcgcc gagtcctcca tggcggactt
     2821 cttcaccctg gagccgggca ccctggtcat ctggatggtg gtctacggct tcttcgcctc
     2881 ggtgctgccg gtctggatgc tgctcgcccc gcgtgactac ctctccacct tcatgaaggt
     2941 cggcacgatc gtgctgatgg cggtctgcgt catcatcgcc atgccgacgc tgaagatgga
     3001 cggcgtcacc tccttcgcga ccagcggcgc gggcccggtc ttctccggtt cgctcttccc
     3061 gttcgtcttc atcaccatcg cctgtggcgc gctctccggc ttccactccc tggtctcctc
     3121 gggcaccacc ccgaagatgg tccagaagga gacccagatc cggatgatcg ggtacggcgc
     3181 gatgctcacc gagtcgttcg tcgccatcat ggcgatgatc gccgcctgca tcatcgaccc
     3241 gggcctctac ttcgcgatca actccccggc cggcgtcctc ggtgacaccg tccagagcgc
     3301 ctcggaggcg gtcgcgggcc tcggcttcac catcagcccg gaccaactgg cccaggcggc
     3361 gaaggacgtc gaggaggcct cgctgctgtc gcggaccggt ggcgccccca ccttcgccct
     3421 cggtatggcc gagatcttcg cggcagcgct gggcggcgcc gggatgaagg cgttctggta
     3481 ccacttcgcg atcatgttcg aggcgctctt catcctcacc accgtcgacg ccggtacgcg
     3541 ggtcggccgc ttcatgctcc aggacaccct gggcaacgtc tggaagccga tgcgccgcgt
     3601 cagctggtgg ccgggcgtct ggctgacctc ggcgatcgtg gtcggctgct ggggctactt
     3661 cctctgggtc ggcgtccacg acccgctggg cggcatcaac cagctcttcc cgctcttcgg
     3721 tatcgccaac cagctgctgg ccgccgtcgc cctggccgtc tgcaccacgc tgctgatcaa
     3781 gtcgggccgc ctcaagtggg cctgggtgac gggcataccg ctcgcctggg acgtggcggt
     3841 cacgctcacc gcgagctggc agaagatctt ctcggacaac ccggccatcg gcttcttcgc
     3901 ccagcgcgcc aagtaccagg acggcatcga cgcgggcgag gtgctggccc ccgccaagtc
     3961 gatgagcgac atgcacaccg tggtgaccaa ctccaccgtg gacggcgtcc tgtcgatcgt
     4021 cttcgcggtg ctgatcatca tcgtcctggt cgacgcgggc cgcgtcagct acaacgcgat
     4081 ccgcaggccc gagtcggcca agctggccga ggcgcccttc gagcagtcga agatcgtcgc
     4141 cccggccggg atgttcgcca ccgccgagga gaaggccgaa ctggccctcg tcggcgccgg
     4201 ggcccctgcc tccgccggtg acggcgacgg cgacgccccc gcgaagcagg gcggcgacaa
     4261 ggcatgagcg gcgaggcggc ccaccacccc ggacgcctcg gcgtcctggc ccaccgcgtg
     4321 cgcgccggcg cccgctggat cggctggtac gtccgggagg tgtcgggcga gacggcgtac
     4381 gagaagtacg ccgcgcacgt ccggagccac gacccggacg ccgaggtgat gacccgcagg
     4441 cagttcgaac gcagtcgcat ggacgcccgc gaggcggacc cgcgcgacgg attccgctgc
     4501 tgctgaccgc cggttgaagc cgccggcccc cgatcgaggg ggccggcggc ttcgccgttt
     4561 cccgggccgg ggccctggcg accgccacac cggtccgggc gcgtacgctc tccgagtcgc
     4621 cgtgccgccc cgcgcgccgc ccgtgaggtc ctccgggccg cccccggggc ccgtttcccc
     4681 tccggggcgc cgacggcccc tcaggggccc actgacggcc tgtccggcgg gcgcccgggc
     4741 cccgcccgag ggcgcctcgg cgaggttcgg gcatcgggtg cgggtggggt cgaatgaccc
     4801 acctcacagc acacccgaca caagatatgg ggccgcttcg cgagcgcggc acaagatgta
     4861 tgctcatgct cgctgtcgcc gcaggggaat ccggtggaag tccggaactg tcccgcaacg
     4921 gtgtgttggt gcgctttcgc gtacccgcga gtccgaagac ctgccgaaca gcgcacccgg
     4981 ccgtccggtc cgggtgccga tgtcgtccgg gcctcgtgga atgggctcgc ggacgcgtgc
     5041 ggagccgtgt gcccatcaag cccggcgtcc cgcccgtacc cgctgccctc cgcaaggctc
     5101 cgagccgagc gagggagagc ttcatgacca tcgcgccagc cgatccgtcg acggccgagg
     5161 tgcgggccga ggagatccag ggccccgggg gcgcgctgct gcgtaccctc accgacctca
     5221 ccgcggacct ccccgacacc gaccccggcc gggtcgccgc cgccgcgctc cggggccgca
     5281 acgccgcctc ggacgaggcc gagctgcggt cgctcgcgac ggaggccgcc gccggtctga
     5341 tctccgagga ccccgcctac tcccggctcg ccgcccgcct gctgacccgc accatcgccg
     5401 aggaggccgc gggccagggc gtcaccacct tcaccgggtc ggtcgccacg ggccaccgcg
     5461 agggcctgat cgcggaccgc accgccgcct tcgtgaccgc gcacgccgag cggctcgacg
     5521 ccctggtcga cccggcggcc gacgaccgct tcggctactt cggcctgcgc accgtgcaca
     5581 gccgctacct gctgcgccac ccgcacaccc gccaggtgat cgagacgccc cagcacttca
     5641 tgctccgcgt cgcctgcggc ctcgccgagg acgactcggt gcgcgccctc gacgaggtcg
     5701 cctcgctcta ccggctcatg agcgccctct cctacctgcc ctcctccccc accctcttca
     5761 actccggcac ccggcacccg cagatgtcct cctgctacct gctggactcc cccaaggacg
     5821 agctggagtc gatctacgac cgctaccacc aggtcgcccg gctctccaag cacgccggcg
     5881 gcatcggcct ggcctactcc cgtatccgcg cccggggttc gctgatccgc ggcaccaacg
     5941 ggcactccaa cggcatcgtg ccgttcctca acacgctcga cgcctcggtg gccgcggtca
     6001 accagggcgg ccggcgcaag ggcgcggccg cggtctacct ggagacctgg cacgccgaca
     6061 tcgaggagtt cctggagctg cgggacaaca ccggcgagga cgcccggcgc acccacaacc
     6121 tcaacctcgc gcactggatc ccggacgagt tcatgcgccg ggtcgacgcc gacgccgact
     6181 ggtcgctctt ctccccctcg gacgtccccg aactgaccga cctgtggggc gacgccttcg
     6241 acgcggcgta ccgcgcggcc gaggcgcagg gtctcgccaa gcggaccatc ccggcgcgcg
     6301 agctgtacgg ccggatgatg cgcaccctcg cgcagaccgg caacggctgg atgaccttca
     6361 aggacgcctc caaccgcacc gccaaccaga cggcgctgcc gggccacacc gtgcactcct
     6421 cgaacctgtg cacggagatc ctggaggtca ccgacgacgg cgagacggcc gtctgcaacc
     6481 tcggctcggt caacctcggc gccttcgtcg acggcggggc gatcgactgg gagcggctgg
     6541 acgaggcggt gcgcaccgcc gtggtcttcc tcgaccgcgt ggtcgacatc aacttctacc
     6601 cgaccgagca ggccgagcgc tccaactccc gctggcggcc ggtgggcctg ggcgcgatgg
     6661 ggctccagga cgtcttcttc cagctccggc tgcccttcga ctcccccgag gcccgggagc
     6721 tctccacccg gatcgccgaa cgcatcatgc tcaccgccta cgagacctcc tgcgacctcg
     6781 ccgagaagaa cggcccgctc ccccactggg accgcacccg caccgcccag ggcgtcctcc
     6841 acccggacca ctacgacacc ggcctcgcct ggcccgagcg gtgggaggcg ctgcgcgccc
     6901 gggtcgcgag gagcggcatg cggaacgcgc tgctcctcgc catcgccccg acggccacca
     6961 tcgcctcgat cgccggtgtc tacgagtgca tcgagccgca ggtctccaac ctcttcaagc
     7021 gcgagacgct gagcggggag ttcctccagg tcaactccta cctggtggag gacctgaagc
     7081 ggctcggcgt ctgggacacc cgcacccgcg aggcgctgcg cgaggcgagc ggttcggtgc
     7141 agggcttcgc gtggatcccc gaggagctgc gggcgctgta ccgcaccgcc tgggagctgc
     7201 cgcagcgcgg cctgatcgac atggcggcgg cccggacccc gttcctggac cagagccagt
     7261 cgctcaacct gttcatggag acgcccacca tcggcaagct cagctcgatg tacgcgtacg
     7321 cctggaagaa ggggctgaag accacgtact acctgcggtc ccgcccggcc acgcggatcg
     7381 cccgcgccgc cggcagctcc gcccccgcca ccgccaccgt cccggcgcag gcggcccccg
     7441 acgcggaggc cgtcgcctgc tccctggaga accccgagtc ctgcgaggca tgccagtgac
     7501 gaccaccccc gacaccaccc cggcagcgaa cgcgcacacc gtcggcgcgg cgaagaacct
     7561 gctcgacccc ggcttcgagc tgaccttgcg cccgatgcgg tacccggact tctacgagcg
     7621 ctaccgggac gcgatcaaga acacctggac cgtcgaggag gtcgacctcc actccgacgt
     7681 ggccgacctg gcgaagctct ccccgggtga gcaacacctg atcggccggc tggtcgcctt
     7741 cttcgccaca ggtgactcca tcgtcgccaa caacctcgtg ctgaccctgt acaagcacat
     7801 caactccccc gaggcgcggc tctacctgag ccggcagctc ttcgaggagg ccgtgcacgt
     7861 ccagttctat ctgacgctgc tcgacaccta cctgcccgac ccggccgacc gcgcggacgc
     7921 cttcgcggcg gtggagaaca tcccctcgat ccgcgagaag gcggagttct gcttccgctg
     7981 gatggactcg gtggacaagc tggaccagct ggagagccag gcggaccgcc gcaagttcct
     8041 gctcaacctg atctgcttcg ccgcctgcat cgaggggctc ttcttctacg gggcgttcgc
     8101 ctacgtgtac tggttccgct cgcgcgggct gctgcacggc ctggcgaccg gcaccaactg
     8161 ggtcttccgc gacgagacga tgcacatgag cttcgccttc gacgtggtcg acacggtccg
     8221 caaggaggag ccggagctct tcgacgacaa gctccaggag caggtcgtcg cgatgctcaa
     8281 ggaggccgtc gaggcggagc tgcagttcgc ccgcgacctg tgcggtgacg gcctgcccgg
     8341 catgaacacc gagtcgatgc gcgagtacct ggagtgcgtc gccgaccagc ggctcacccg
     8401 gctgggcttc gccccggtgt acggctcgca gaacccgttc tccttcatgg agctgcaggg
     8461 tgtgcaggag ctgaccaact tcttcgagcg ccgggtctcg gcctaccagg tcgcggtcga
     8521 gggcacggtc tccttcgacg acgacttctg accggccccg cccccgcgaa cgcccgccgc
     8581 ccggcccctc gtcctgaggg ccgggcggcg ggcgtcggtg cggggcgcgg tgggggtcag
     8641 cggctctcga cccggaagac ggcgcgcttg ggctggaggg tgatcccgat ccggggcgcc
     8701 ggatcggtct cggggacggg gacgagccgc cagcggggca gcacggtggc gagcatcagc
     8761 gtggcctcga ccatgctgaa gtggtcgccg gggcatttcc ggttgcccgt gctgaacggc
     8821 atcatcgcgt actgcggtac cttttcggcc cgttcgggaa tccaccggtc cgggtcgaag
     8881 acgtccggcc ggtcgaatga gcgcggatcg tgctgcatcg catacgcgct gtagatgatg
     8941 tccgctccgg ctggaatgcg atagccaccg agttctgtgt cggtgacggc acggcgggtg
     9001 aatatccacg ccgcaggccg tatccgcatc gattcgacga tgacattgcg ggtgtggtcg
     9061 agggagccca gatcgccgaa attgaccggc cggtccgttg ccacggatag tgcctcctcg
     9121 gccacccgct gttcctcggc cggatgttcg gtgaggagct ggaagcacca ggcgagtgtc
     9181 gaggcgacat tctcggcccc ggcgacgatc agcgagacga gatggtcgtg aatctcctga
     9241 tcgctgagcg gcctgccttc gccgtcctcg gaggtgagca gaatgtcgag cagatcgtcg
     9301 gcgcccttgc cctgcgcgtg ccgctcggcg atcacctcgt cgacgaggtg gtggaggtcg
     9361 gccagcgccc gctcgaagcg ccggttggcg ggggtcggca gccggtgcag cggcccgaag
     9421 gagaggatca tccgccggta caggccgctg aagacggtgt gcagcgaggc gctgatccgg
     9481 tccgccttcg cgccgatcga gtcgacctcc agcagcgagc gggcgaccac ccggaccgcg
     9541 cagctgaacg tctcggcgcc gatgtcgacc acctgcccgt cccgccagcg gtcggccatc
     9601 gcccgcgcct cctgctccat cacggtcgcg tacgaggcga tccgctcggg ccggaaggcg
     9661 ggctgcatca tgcggcgctg gcggcgatgg tcggccccgt tgctggtggc cacgcccttg
     9721 ccgagcagca cttcgaggtt ctcccagagc ggcccgccga cctggaactc ctgggagttg
     9781 cgcagcagcg ccccgaccag cccgggcgcg cagaccgcgt acgccgtctt cgggccgagc
     9841 ttcacgcgga ccaggtcgcc gtggtcgcgc agcccggtga ggaaggccag cgggtcgcgg
     9901 accaggctcg gggcgtggcc caggacgggc acgctgccgg ccaccagggg cggggtgcgc
     9961 gggtccgggg cggcggcgcg ttcggtggtg gattcggcgc tcacgcgtca cctgccagat
    10021 cgctgacgta gggcggggtg ctccggtcgt cccagctgtc gacgcggtaa cggccggact
    10081 cgtggtggaa ccagtagacg gaggagaacc agttgcgcat gttgaagacg gccgagccga
    10141 cggcctcggc gacggacctc gcctccgtgg agccggctcc ttcggggagt gcggcgagat
    10201 gtccggcgag gagttcccgc aattccttct ccgccacttc gaattcggtg acgcagttct
    10261 ccacgcggct ccgcacctct gtcacggcct cttcgagcga cagcccctcg tggcgtatga
    10321 gactgattcc cagattgtgc tggtcgtcgc ccgccagttc tttcgggagt gagcagaggt
    10381 cgttgtacca ggcggagaaa tcctggcagt gccgggccgc cgagagaaag ggaccactgg
    10441 tcctcagggc tgccgggatc tcgcgccccg cggtgggttc gagaaggtcg atccagacgg
    10501 agtggccgaa ggtgtgtcgg cgcagttcga tgtattcggc gacctgcggg gtgactttgg
    10561 tgacgcggtt ctcgaattcc tggtcgtagg cgccgacgat ggcgtggaaa tggcgggcga
    10621 accgctcgtt ccaggcgggg ctgaggaagc cgttcagcct gtggacggtc tcggcgaagg
    10681 ccgcgaccag cggctccggg tgcgcgaggt ggtcgccggg ggcgtccagc gcggtgtgca
    10741 gttcggcgct gagccggtac caggcggtgc gccgcccgtg gacggcgtcg cggtcgtgct
    10801 ggtcgtccca gacgaagaac caggtactga agtcggaaat cgccgagatg acgtccctcg
    10861 gcgcacccac gtagtagccg gcgatgaggt cggtgtagcg gagttcgtcc gcatagcggg
    10921 tgaccttgtc ggcgggcatc agccgctttt cgagcagcca ggcgcgggac tccacctgaa
    10981 gctttggcca atactcgtgg cgatgtcgcg gaaacgcttg ttcgatcacg ggcaacgcca
    11041 gcgcctcggg caccgaagtc gcctgcgccc gtgcggtgcc gtgtgggaaa gcaggcacga
    11101 acaaacccct ttcatccgct ttctgccgac gccccctgcc gggcggggcg ccgcgcggtg
    11161 gtgtatcccc cgccctttcc attgagcacc acaactgacc gttctggaaa cagatttgct
    11221 ccattcgcca ccccgcgccg acccgaagat cgccatacgt gtccgaaaat tgatcatgac
    11281 cccacgacac gccaccgccc cgcctcccgt gcggggagag cggggcggtg cgggtccgcg
    11341 gcggcgggcc ggcgggggtg cctcagtcgt tggggaccgt ctcgtagcgc ggagtgccct
    11401 cggccatctg ccgcagggcg tccttgcgct cgcgcttgga gagccggtcg atgtagaggt
    11461 acccgtacag gtggtccgtc tcgtgctgga ggcagcgggc gaagtagccg gtgccacgca
    11521 ccacgatcgg gttgcccttc tcgtcctgcc cgcgcaccac cgcgtagtcg gggcgggcca
    11581 gcgccgcgta ggcggtgggg accgagaggc acccctcgtt ggagtcgtcg aggacgcggc
    11641 gctcggaggg cagctcgtcc agaaccgggt tgcagaccac gccgacgtgg cgcacgccct
    11701 cgtcgtccgg gcagtcgtag acgaagacct tcttgtccac gccgatctgg ttggcggcca
    11761 ggcccacgcc ctccgccgcc cgctggctgg cgaacatgtc gtccaccagc tgggccagct
    11821 ccgcgtcgaa gaccgtcacg tccttcgtct cgcggtgcag taccgggttg cccaccacgg
    11881 tgaccggacg cgcggtgccc cgggcgcggt aggccgcctc acgctcctcg gtgtcctcgg
    11941 tgtcgatgac gaatccctcg tcgtcgaccg ccagcacacc gcccgccacc gcctgctgct
    12001 ccgtgtcctg ctgcgccatg tccgcttccg cgccttcctg ggaacccgtt gtccgtgccc
    12061 gtacagccta cgcgggggcc ggggcgcggg tggccgcgag gacggagcgg ctcagcacac
    12121 ctcttcgagg tcgcgccagg cgcgggtgtc cgggctgtcg gcgacccagc cgtcgagcag
    12181 gccgcgcacc agggcgggcg gggcggcgat gccgcactcg cgctcgggga cccacaggtc
    12241 gccctcgccg gaggtggtcc ggtggcccag cgggccgggc tggcccggtt cgctgtggtc
    12301 gtgcgggtcg acgtgccgct cgccgccgcc ctcgtcgctc ggcatccggc tctccgagca
    12361 ggtccggcag agcagccgca ccgacgagga ccagtcctcg gcggcgaacc cggcgtcggc
    12421 cgccagcagc tccagcgcgt cccggtcggc cggggcctgc gcctccagca gcaccaccca
    12481 ggtcggtacc ggggagggcg cccacagctc gatctcgtcg aagaccggat aggtgtcacc
    12541 cgaagcggtg gtccgttcgc cgtgcgggac cccgtcgtgc aggatcacct cgccccagcg
    12601 gcggccggag gagggcagcg ggatcgactg gacctcgatg cgggccgggt ccagccgccg
    12661 gccccagacc acctcggcct ccccctcggg ggagatccgc acggcggcgc tgcccagccc
    12721 catcccggac ggctcgccgg aggccgccgc gtccccgggg atcttcagtc cgtacgcctg
    12781 ccaggcacgg cgggccagcg gccagtcctg gagggcggtg gcggcgatgc cgacgttcca
    12841 ccagtcgggg gcgccggtgt cccggtccag cagggcgacg gcgcgcaggc ccgcggtacg
    12901 ggcctgttcc cagtcgtggc ggaacttgtg gagcagggcg aggttgaacc aggactcgga
    12961 gagccacggc tccaggtcgg cggcgcgcgt gagcagggcg cccgcgtcct cgtaacggcc
    13021 gtcgccgatc aaggtgaacg ctcggtcggt cgcctgccgc caggaggcgg aggggcggtg
    13081 ccgtcccttg ccgaagatcc tcacgattcc cgcctgccgg tgtccggtcc cttcgggtcc
    13141 cccgcccgtg cgccggcgct gagcctggag acggggtacc tcttcgcatc caaccacgga
    13201 cggttggggc gtcgctcatt acccatgggt tacccactgg cgtgaggtgc agaccttctc
    13261 ggaccgggtc gctctatcga gtgacttgcc cagggagcgt ccggcctgta tccgcccgct
    13321 cccgggccgt cccggacgtc agggcgtgtc cgccacttcc gtcgggacga tgtcgtgctg
    13381 cgggaccgcc tggcccgccc ggatcatgtc caggcggctg atcaccttgt cccgcaggtc
    13441 cgcggggacg tcgtcctgac cgcagcaccg cttgaccagc ttcttgacgg cctgctccag
    13501 gccgtacttc tccaggcagg gagagcactc gtcgaagtgc gtgcggatct tgttggagtc
    13561 gctgtcgggc atctcgtggt cgaggaactc gtagagatgg tccaggactt cactgcaatc
    13621 cgtctcgtgc ggctctccgc agctcatgac cccgcgcctt tccgctcgtt cggttccgcc
    13681 gcgctcgccc cggaaccggc ggggaccagc ccgcgctcgc gggcatagtc ctccagcatg
    13741 ccgcgcagct ggcggcggcc gcggtgcagg cgggacatca ccgtcccgat gggtgtaccc
    13801 atgatgtccg cgatctcctt gtaggcaaac ccctcgacat cggccagata gacggcgatg
    13861 cggaactcct cggggatcgc ctgcagggcg gacttcacgt cggagtcggg aaggtggtcc
    13921 agcgcctggg actcggcgga gcgcagaccg gtcgacatgt gcgactcggc acgcgccagc
    13981 tgccagtcct cgatctcctc ggcggcgctg cgctggggct cacgctgctt cttgcggtac
    14041 gagttgatga aggtgttggt gagaatccgg tagagccatg ccttgaggtt ggtgccctca
    14101 cggaactggt ggaacgacgc gtacgccttg gcgtaggtct cctggaccag gtcctcggcg
    14161 tcggccgggt tgcgggtcat ccgcagggcc gccgagtaca tctggtcgag gaaggcgagc
    14221 gcgtcccgct cgaaccgcgc ggtccgctcc gccgaggtct cctcgggctt ctcgggcaca
    14281 tcctggcttc ccgcgtcggt ccccgtgacc ggacccacct ccttcagcgc tgtggcgggc
    14341 ccgccggccg gaccgcccga atcggaggat agaccacgct cctggacttc ccggcgatcc
    14401 cggccggagc cagtgcgcac gggcgcctgc agcaccgacc actccaggtc ggtggcgcgc
    14461 tcgcggctcg ggcagatggt cgaacccatg cggcggactt cctctcgtga tcaacgctgt
    14521 cgaagcacct tcgacccgca caacagccgc cgcccgctcg gcattcccgg cccagcacga
    14581 cgccggcccc agtccgccgc gaggctcgtc ccaggtcgcc gcaaggctcg tctcagcccg
    14641 ccgcgacacc cgcctcagcc caccggcagc cgctccagcc acgcccccac cgcgtccgtg
    14701 atcaccccga gcgcctcctc ctggccgacg ggcgccttct tcggcacggc gaacccgtgg
    14761 tcgccgtacg gcacctcggc cagctcgtag ctccccccgg ggaactcctc cggccgcccg
    14821 aacggatccc gcccgccctg caccaccagc gtcggcacgc ccgtcccgag cagctcctcg
    14881 gcccggctgc gctccggctt ccccggcgga tgcagcggaa agctcagcgc gagcaccccg
    14941 gcggccccca acttggcccc ggcccggcag gccacccgcg cccccgcact acgcccaccc
    15001 gcgacaaccg gcagcccctc cccggccacc tcgtcccaga ccgcctccca ccccttgtcc
    15061 agcgtcttcg gcgccggcgc caccttcttc cccgccaccc gccagggctg ctccaccaac
    15121 gccacactca ccccggcccc cggcaacgcc cccgccaacg ccaccagatc ccgagcctcc
    15181 accccacccc cggccccgtg cccgagcgcc agcacgatgc gcggcgcccg cgcccgcacc
    15241 cacgtgaccc gcgcctcccc cgcggcagtg accacactca cccgctcccc cgcccccggc
    15301 acagcgggaa cagccacacc ctcagacctc gatacgttca tcccgccatc ctgccccgac
    15361 ggcgaacccc gaccacttca gctgagccgc catgggcccc gcaggcacac cctcaccccc
    15421 tctcaagccc gatccagccc ggccggcgct tgaggccacc cctgcgaaac ccgcacgcta
    15481 gaacagcgtg ccgacctcag gcccgtccag ctcggacacg agcccgggcc cgttgttgcg
    15541 cacattgctc accgccgtgg ccacgggata ggcccgcatc aacccctcgg ccggcgcagc
    15601 caacaactcc cgcacctcct ccacatccgt cttcgacgga tcaagccacg cgtcccactt
    15661 gtccggcgtc agcatcaacg gcatccgggg atggatgtcg gccagcgccc gaggcccctc
    15721 ctcgggcccc accccgagcg gcgccgtctc cgcctcggtc gtgatgacgg aacacgtcac
    15781 ccaccaggcc cgcggatggt ccccgggcag cgagggatcc cgccagaact cgtacagccc
    15841 ggccatggcg aagaccgacc cgtcggcagg cgtcacgaag tagggctgct tacggacccg
    15901 cttccgcttc ccctcctcct ccagcttccg ctcctccgga gcggtcaccc actcgtaata
    15961 gccgtcggcg gggaggatgc agcgccgcga ggcgaaggcc cggcggtagg cgggcttctc
    16021 gtggacggtc tcggcccggg cgttgatcat gcgggcgccg ccgtcgggcg aggtggccca
    16081 ggaggggacg agcccccagg tcagcgtccg caactgccgt acggggcgcg ggtcgtcgct
    16141 gcccttgacc ggccggtcga ggatggcggg aacctccttg gtgggcgcca cgttccagtc
    16201 ggggacgagg gtctcggtgg gcgcgggggt cgcccccgcc tcgtggccgt cctcctggcc
    16261 gtccgccgcc tcgctcagct cggtcttctc gacgccgaag atctcgctga ggtcctcggg
    16321 gctccgggtg gccgcgtacc gtccgcacat acgtgccaga ctgccaggcc gtgccaccgg
    16381 accgccacca gttggggccc ggggccgcgc gtcccaccct cgcgaggagc cgcccgagta
    16441 tgcagagcac caccgccgcc ccggccaccg acctgtggga ccgcgtcacc gggacccaga
    16501 ccgcccccga gttctggctg gtcgtggcga ccggcgtggc ggcgctcgcc gtggtcctgt
    16561 ggggcccggc ctggcgcccc gcacggaacg cgatcaccat cgcccacgag ggcggccacg
    16621 gcctgatcgc cctggtcacc ggccgcaccc tggaggggat acgcctccac tcggacacct
    16681 cgggactgac cgtgagccgg ggcaggccga ccggcccggg catgatcctc accgccctcg
    16741 ccggctacac cgctccctcc ctcctcggcc tcggcggcgc ctggctgctg gccgccgggc
    16801 acatcacgtt gctgctctgg gtggcgacgg ccctgctgct cgccctcctc gtgatggtcc
    16861 gcaacgccta cggggtgctg acggtgctga tcaccggggg cctgttcgtg gcggtctcct
    16921 ggctggccgg ctccgaggtg caggccctct tcgcgtacgc ggcggtctgg ttcctgctgc
    16981 tgggcggggt ccgcccggtc ttcgagctcc agtccaagcg gcggcgcggc ggcgccccgg
    17041 actccgacgc cgaccagctc gcccggctga cccacgcccc ggcggccatc tggctcttcc
    17101 tcttccacgc ggtggcgctc tgctccctga tcggcggcgg cggctggctg ctcggccggt
    17161 gaccgtgcac gggtacgggg ggctgggcgc actaaagtga cggcatgacc ctgaaccccg
    17221 tatccacccc cctctggcct gccccgtacg cgaccggagc cgtcgaggcg acggtccagg
    17281 taccggggtc caagtcggtc accaaccgcg cgcttgtgct ggcggcgctc gccgccgagc
    17341 cgggctggct gcgccggccg ctccgctcgc gtgacaccgt gctgatggcg gaggcgctgc
    17401 gcaccctcgg cgtgggcatc gaggagaccg tctcgtccga ctcggcggca ccgggcagca
    17461 ccctggccgg gggcggcgag gcgtggcgga tcatcccgtc cggcctgcgc ggccccgcca
    17521 ccgtcgacgt cggcaacgcg ggcaccgtga tgcgcttcct gccgccgctc gccaccctcg
    17581 ccgacggtga catccgcttc gacggcgacc cgcgctccta cgagcgtccg ctgcacggcg
    17641 tgatcgacgc gctgcgcgcg ctgggcgccc ggatcgacga cgacgaccgg ggcagcctgc
    17701 cgatgacggt gcacggcacg ggctcgctcg acggcggcac ggtggagatc gacgcctcct
    17761 cgtcctccca gttcgtcagc gccctgctgc tgtcggcgcc ccgcttcaac cagggcgtcg
    17821 aggtccggca catcggccca cggctgccgt cgatgccgca catccggatg accgtcgaca
    17881 tgctgcgccg ggtcggcgcc caggtggacg agccggagtc gggtggcgag cccaacgtct
    17941 ggcgggtcac cccgggcgct ctgctcggcc gggacctcac cgtcgagccg gacctgtcga
    18001 acgcccagcc gttcctggcg gcggcgctgg tcaccggcgg ccgtgtggtc gtcccggact
    18061 ggccggccca caccacgcag ccgggtgacc ggctgcggga gatcttcacc acgatgggtg
    18121 gttcctgcga gctgaccgag gcgggtctgg tcttcaccgg ctcgggccgc gtccacggca
    18181 tcgacgtgga cctcggcgag gtaggcgagc tgaccccggg catcgcggcc gtcgcggccc
    18241 tggccgacgg cgagtccgtc ctgcgcggcg tcgcccacct gcggctccac gagacggacc
    18301 ggctggccgc gctcaccaag gagatcaacg agctgggcgg cgacgtcacg gagaccgccg
    18361 acggcctgcg catccggccc cgcccgctgc acggcggcgt cttccacacc tacgacgacc
    18421 accggatggc gaccgccggt gcgatcctgg gactggtggt gaaggacgtc gagatcgaga
    18481 acgtcgccac caccgcgaag accctgcccg acttccccga cctgtggacc ggcatgctcg
    18541 acgggaccgg gcagtgacgg ccgggagctg aacgatgcgc cgttacggaa agaaccccga
    18601 cgaggacgac atccgcgtcc gccccagccg ccggggcagc cgcccccgca cccacacccg
    18661 ccccaagcac gaggacgccg ccgagggcat ggtgctcacc gtggaccggg gccggatcac
    18721 ctgcctggtc gagggccgca cggtgaccgc gatgaaggcg cgcgaactgg gccgcaaggc
    18781 ggcggtggtg ggcgaccggg ttgcgctggt cggggatctc tccgggcaga aggacaccct
    18841 ggcgcggatc gtgcggatcg gggagcgcgc ctcggtgctg cgccgcacgg ccgacgacga
    18901 cgacccgtac gagcgggtgg tcgtcgccaa cgccgaccgg ctggcggtcg tcacggcgct
    18961 ggccgatccg gagccccggc cccggatgat cgaccgctgc ctggtcgccg cgtacgacgg
    19021 cggcctggag ccggtcctgg tgctgaccaa gtcggacctg gcctcccccg actccctgct
    19081 ggacacctac cgggcgctgg gcgtgccgta cgtggtgacc agccgtgagg agctggagga
    19141 cggctcggcc gtgcagcggg tcagggagct gctggacggc catgtcaccg ccttcgtggg
    19201 ccactcgggt gtcggcaaga cgacgctggt gaacgcgctg gtccccgagg agcagcggcg
    19261 ggtcaccggc cacgtcaacg cggtcaccgg ccgcggccgg cacaccacgg tctcggcgct
    19321 ggcgctgccg ctggccgacg ccgcccccgg cagctgggtg atcgacacgc cgggtgtgcg
    19381 ctcgttcggg ctgcaccacg tcgacccctc ccgcgtgatc cacgccttcc ccgacctgga
    19441 gccggggacg gagcagtgcc cgcgcgggtg cagccacgac gaggcggagt gcgcgctcga
    19501 ccagtgggtg gccgacggcc acgccgaccc ggcccgcctc aactccctgc ggcggctgct
    19561 ggcgaccagg gagcgccgcg agggcgactg acccgggcac ggcctgcggc gcgacgagcc
    19621 gggccgggtc gcctgcctca ccggacgaca cgggcataat cgcccgaagc cgtacaaggt
    19681 gtgcgcggga tcgtttcggc gggcggaaag gctcattcat ggcatggctg ctggtcgtcg
    19741 tcgcggggct gctggagacg ggtttcgccg tctgcctcaa gctgtcgcac gggttcaccc
    19801 ggctgtggcc gacgatcgcc ttcgccgcgt tcgccctcgg gagcttcggc ctgctgaccc
    19861 tggccctcaa gcgcctggac gtcggcccgg cctacgcggt gtggaccggc atcggcgccg
    19921 ccggcaccgc cacttacggc atgatcttcc tcggcgacgt ggtctcggtc ctgaagatcg
    19981 tctccatcac cctcgtcatc tgcggcgtca tcggcctcca gctctccggc tcggcccagt
    20041 gacccgcccg cgccgccgcc ccgcccccgc accccccacc accggcggcg ccacgatccg
    20101 ggagagggcc aggcgcagaa cgcattcgca ctcgcgggcc agttcgcgcg ggtcggtccg
    20161 gggccgcgcc gactcgtcga gggcggccac ggcacggtcg cgggcggcgg cgaggaggtc
    20221 gccggggccg gggagcggga gttcggcgcg gcgctgggcg gcgggggcgg tggcggtggc
    20281 gcgagccggg cgcggtgcgg gcagcgggtc gccccagcag ccggtcagca gggagcgcag
    20341 cagggtgccg gggcgggcgg cggccacggt ccagtcggcg gcggcccgca gccgctcgcg
    20401 ggggtcggtg gcggggcggg ccagcgcccg ttcgatcccg gcgaggtagc cgtcggcggc
    20461 ctgccgggcc agggcgcggg cgagtccttc cttgctgccg aactcgttgt agagcgtctg
    20521 ccgggagacc ccggccgagg ccgcgacctc acccatccgc accgcgctcc acggccggcg
    20581 ggccaggtgg gcctcggcgg cgatgagcag ggctgcgcgg acttccggca tggctgcctc
    20641 cccggcaagg gtcgtgcggg gaagtctggc gcgggcgcgg gtcgtgtcaa gggggtgtgc
    20701 gcgcgaggtg ggggcgccgc gcccgccggt gaccggatgg cccggcgcgg ccggagatcg
    20761 atactgtttc gcccatggcc gactatcacg atgatctgcg tctcgcccat gtgcttgcgg
    20821 acgccgccga cgcgaccacg atggagcggt tcaaggccct cgacctgaag gtggagacga
    20881 agccggacct cactccggtg accgaggccg acaaggcggc cgaggagctg atccgcggtc
    20941 acctcgcccg cgccaggccg cgcgacgcga tcctc
//
