LOCUS       NZ_KI421498            10849 bp    DNA     linear   CON 24-JUL-2024
DEFINITION  Phaeobacter inhibens DSM 16374 PhainDRAFT_scaffold1.1, whole genome
            shotgun sequence.
ACCESSION   NZ_KI421498
VERSION     NZ_KI421498.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Phaeobacter inhibens DSM 16374
  ORGANISM  Phaeobacter inhibens DSM 16374
            Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
            Roseobacteraceae; Phaeobacter.
REFERENCE   1  (bases 1 to 3361358)
  AUTHORS   Klenk,H.-P., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (29-AUG-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            country                           :: Germany
            environment                       :: Aquatic
            investigation_type                :: bacteria_archaea
            lat_lon                           :: 52.45 13.45
            project_name :: Phaeobacter inhibens T5, DSM 16374
            sequencing_meth                   :: WGS
            ref_biomaterial :: DSM 16374, LMG 22475, CIP 109289, CECT 7251
            finishing_strategy                :: Level 2: High-Quality Draft
            GOLD Stamp ID                     :: Gi10860
            Current Finishing Status          :: Level 6: Finished
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2010
            Gene Calling Method               :: Prodigal 1.4, GenePRIMP
            Isolation Site                    :: Isolated from water, Germany
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 25C
            Gram Staining                     :: Gram-
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Unknown program v. before 2012-08-13
            Genome Coverage                   :: Unknown
            Sequencing Technology :: 454-GS-FLX-Titanium; Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000473105.1-RS_2024_07_24
            Annotation Date                   :: 07/24/2024 00:56:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,924
            CDSs (total)                      :: 3,868
            Genes (coding)                    :: 3,840
            CDSs (with protein)               :: 3,840
            Genes (RNA)                       :: 56
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 28
            CDSs (without protein)            :: 28
            Pseudo Genes (ambiguous residues) :: 0 of 28
            Pseudo Genes (frameshifted)       :: 14 of 28
            Pseudo Genes (incomplete)         :: 18 of 28
            Pseudo Genes (internal stop)      :: 7 of 28
            Pseudo Genes (multiple problems)  :: 9 of 28
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:11:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 368979
            Orig. end                         :: 379828
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KI421498.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 404179
            Source DNA and Organism available from Hans-Peter  Klenk
            (hpk@dsmz.de)
            Source DNA available from Hans-Peter  Klenk (hpk@dsmz.de)
            Organism available from Hans-Peter  Klenk (hpk@dsmz.de)
            Contacts: Hans-Peter  Klenk (hpk@dsmz.de)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10849
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10849
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10849
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5849](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5849)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(796..814)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 22.01"
                     /tool="antismash"
     gene            911..2377
                     /locus_tag="INHI_RS0105355"
     CDS             911..2377
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014875100.1"
                     /locus_tag="INHI_RS0105355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_027246989.1"
                     /sec_met_domain="Aldedh (E-value: 5.2e-159, bitscore:
                     527.2, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQFQQYIGGVFSDGSARFESRDPATGEVWAMMPEARAPDVDAAV
                     AAACAAFHARDWAGMTATVRGKLLYRLADLIAENAETLAQLEARDTGKIIRETSAQIAY
                     VADYYRYYAGLADKIEGAHLPIDKPDMEVWLRREPLGVVAAVVPWNSQLFLAAVKIGPA
                     LAAGCTVVLKASEEAPAPLLEFARIFDQAGFPRGVLNVITGFGADCGAVLTAHPGIDHI
                     AFTGGPDTARHVVRNSAENLASTSLELGGKSPFIVFEDVDIDSTVNAQVSAIFAATGQS
                     CVAGSRLIISNQIKDVFLRSLKEKAERVRIGAPQMTETEVGPLCTDAQMRRTVELVAAS
                     LAAGARIVTGGQPLEGEGNFFPPTILDCSSAPDAPCLREEFFGPVLSVCGFDTEAEALA
                     LANDTAHGLASGVFTRDLTRAHRMIRGIRAGIVWVNTYRAVSPIAPFGGQGLSGHGREG
                     GLQAALDYTRVKTVWLRTSDEPIPDPFVMR"
     gene            complement(2475..2681)
                     /locus_tag="INHI_RS0105360"
     CDS             complement(2475..2681)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014875099.1"
                     /locus_tag="INHI_RS0105360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cold-shock protein"
                     /protein_id="WP_014875099.1"
                     /transl_table=11
                     /translation="MASGTVKWFNTTKGYGFIEPEGGGKDVFVHISQVERSGLTGLADN
                     QKVDFEMTEGRDGRQMASDIRPQ"
     gene            2902..3222
                     /locus_tag="INHI_RS0105365"
     CDS             2902..3222
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014875098.1"
                     /locus_tag="INHI_RS0105365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arsenate reductase family protein"
                     /protein_id="WP_027246990.1"
                     /transl_table=11
                     /translation="MQLFGLKACDTCRKALKQLPEAELVDVRADGVPEAILTAALAQFG
                     DRLVNTRSTTWRGLSEAERAEDPMALLKAHPTLMKRPLIKSGDDLHLGWDAKTKAALGV
                     EG"
     gene            3263..3631
                     /locus_tag="INHI_RS0105370"
     CDS             3263..3631
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014880420.1"
                     /locus_tag="INHI_RS0105370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_027246991.1"
                     /transl_table=11
                     /translation="MRNAALVLGIVAGLIGMVVGFAGYGYTAAVEYFGEIDGIARQVDD
                     VDQLRLLAVISPILALAGGAMALSRALWGGVLLLASAAGLYAGFGLNVFTIFPISLALL
                     GGLLALAAGKPDEPKAHF"
     gene            complement(3709..4245)
                     /locus_tag="INHI_RS0105375"
     CDS             complement(3709..4245)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014875096.1"
                     /locus_tag="INHI_RS0105375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DoxX family protein"
                     /protein_id="WP_014875096.1"
                     /transl_table=11
                     /translation="MHALVSSYTSLTGRADRLSAFIIPTLARLVFAAVLLVYYWNSAGL
                     KIDGSIFSPSAGAFGQIFPKAAEAVLYDVSQLNILQRLVIFAGTIAEYVLPALILVGLF
                     TRLAALGTIGFIWVQTIVDVTGHGVKLGSLFDNSIGLVDQRVMWTFLLLVLVFKGAGPL
                     SLDALARRATAPAAA"
     gene            complement(4249..5004)
                     /locus_tag="INHI_RS0105380"
     CDS             complement(4249..5004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014875095.1"
                     /locus_tag="INHI_RS0105380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA-binding domain-containing protein"
                     /protein_id="WP_027246992.1"
                     /transl_table=11
                     /translation="MTVSQTEFTHAMMDAGQPVPEGLLDATGQPAGRRFSVYRNNIAVS
                     LSEAMHSAFPLIGKLLGKQNLDGLAGMYLRAHPPSSPLMMHYGAEFPAFLAGMEQLKHL
                     GYLPDAARLDLALRRAYHAGDATAVAPARLAALPPEALMATRLTLAPAVALLGSPWPIY
                     DIWRFNTEENAPKPRHMAQDVLITRPEFDPIIQELPPGGADWITALTSGATLEEALTEV
                     QADHPDFDLSHTLALLLQGGAIIDLDRKG"
     gene            complement(5001..5849)
                     /locus_tag="INHI_RS0105385"
     CDS             complement(5001..5849)
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014875094.1"
                     /locus_tag="INHI_RS0105385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF692 family multinuclear iron-containing
                     protein"
                     /protein_id="WP_014880418.1"
                     /sec_met_domain="DUF692 (E-value: 1.6e-87, bitscore: 290.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDAAPFLPAATGVGYKPQHFADILADAGPVKWLEIHAENYMGDG
                     GRPIAQLRHLCEQFAISVHGVGLSIGGEGPLDADHLARLKHLVGWLNPASFSEHLAWST
                     HDSHFYNDLLPLPYTDATLARVCDHINQVQDTIGRRMLLENPSSYLAFAESSWSEPEFL
                     TEITRRTGCGLLLDVNNVFVSATNLDFSPQGYIDAFALDQVGEIHLGGHDEDEDDHGKP
                     LLIDSHGAEVVDPVWALLDYTLAKSGPKPVLVEWDTDVPDWPVLAAEATRAATALERVS
                     A"
     gene            complement(5918..6223)
                     /locus_tag="INHI_RS0105390"
     CDS             complement(5918..6223)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014875093.1"
                     /locus_tag="INHI_RS0105390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2282 domain-containing protein"
                     /protein_id="WP_014880417.1"
                     /transl_table=11
                     /translation="MSNTAKSLAVAGAVAAALTSAMVTPAAAQSKEKCYGVSLAGQNDC
                     AAGPGTTCAGTSTVDYQGNAWTLVDAGSCEGMDLPAMADGGDRKGSLEPLERDLPA"
     gene            complement(6458..8404)
                     /gene="thrS"
                     /locus_tag="INHI_RS0105395"
     CDS             complement(6458..8404)
                     /EC_number="6.1.1.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014880416.1"
                     /locus_tag="INHI_RS0105395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="threonine--tRNA ligase"
                     /protein_id="WP_027246993.1"
                     /transl_table=11
                     /translation="MAQVSLTFPDGNARSYDAGVTPAEVAASISTSLAKKAISATVNGA
                     HWDLQWPIDSDAAIAIHTMKDEEQANELIRHDLAHVMARAVQDIWPDTKVTIGPVIENG
                     WYYDFDRAEPFTPEDLGTIEKKMKEIINKRDEVRTEVWDRDRAIQHYTDLNEPYKVELI
                     ESIPGDEPLRMYWHGDWQDLCRGPHLQHTGQLPGDAFKLMSIAGAYWRGDSDRAMLQRI
                     YGVAFTGKEKLKAHLHMLEEAAKRDHRKLGREMNLFHMQEEAPGQIFWHPNGWKIYTTL
                     QDYMRRMQDRDGYVEVNTPQVVDRKLWEASGHWDKYQENMFIVEVDEDHAREKAVNALK
                     PMNCPCHVQVFNQGLKSYRDLPLRMAEFGSCARYEPSGALHGIMRVRGFTQDDGHIFCA
                     EDQIESETAKFIAFLSKVYADLGFHDWTIKLSTRPEKRIGSDESWDLVEKALGDACKAA
                     GYEYELLEGEGAFYGPKLEFTLTDAIGRNWQCGTLQVDPNLPERLDANFIGQDGSKHRP
                     FMLHRATLGSFERFIGILIEEHAGKLPFWLAPRQVVVASITSDADDYVNEVVETLRAAG
                     VRAEADIRNEKINYKVREHSVGKVPVILAVGHREVEERTVSVRRLGEKQTKVEALDAVT
                     KALAVEATPPDLL"
     gene            complement(8577..9581)
                     /locus_tag="INHI_RS0105400"
     CDS             complement(8577..9581)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014880415.1"
                     /locus_tag="INHI_RS0105400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4105 domain-containing protein"
                     /protein_id="WP_027246994.1"
                     /transl_table=11
                     /translation="MPRALRLFCLGLLCLLILLTTLWGAMALWYRLPVDSLWRTAAASG
                     FAGLGLATLWAVIRGRALRGLSTFCLALAALIWWWASLTPPAEAQWSPDVARQVTGTRD
                     GDILTLTDVRNFDWSTPTEFTPRWETRSYDLSQLNSVDLFMSYWAGPEMAHMVVSFGFE
                     EGAHIAWSVEVRRQVGGGFSPIADLFKTNTLVLIAADERDVVGTRTNARGEDVQLFRID
                     TDPDTARALLMQYVEAANRLAAQPQWYNSLTSNCTTVVMTMIRTIVQDVPLDWRVLANG
                     YLPEYAHDQGVLAAGYSTEELRKRGSITARAQAQGITPDYSAMIREGVPAPAP"
     gene            9825..10604
                     /locus_tag="INHI_RS0105405"
     CDS             9825..10604
                     /NRPS_PKS="Domain: Abhydrolase_1 (56-145). E-value:
                     6.3e-12. Score: 37.5. Matches aSDomain:
                     nrpspksdomains_INHI_RS0105405_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014880414.1"
                     /locus_tag="INHI_RS0105405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carboxylesterase"
                     /protein_id="WP_027246995.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.8e-09, bitscore:
                     34.2, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.5e-09, bitscore: 34.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAPQFLDTDTGRRLAYHLTPASGDATAPMVVFLGGLKSDMEGTK
                     AIHLEAWTKARGLGFLRFDYSGHGESSGTFEEGCIGDWHQDTLAAVQALTKGQILPVGS
                     SMGGWQALLLARALPERVAGLVTIAAAPDFTEDGYWANFTDAQKAELEAHGQVELPSDY
                     MEPYVITKRMIEDGRNHLVLRDPLVLSMPVRCLQGTADTAVSTETALRLLDHATCADMR
                     LQLVKDADHRFSDPACLALIETAVAEVLGLSGADAIS"
     aSDomain        9993..10259
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_INHI_RS0105405_Abhydrolase_1.1"
                     /evalue="6.30E-12"
                     /label="INHI_RS0105405_Abhydrolase_1.1"
                     /locus_tag="INHI_RS0105405"
                     /protein_end="145"
                     /protein_start="56"
                     /score="37.5"
                     /tool="antismash"
                     /translation="GLGFLRFDYSGHGESSGTFEEGCIGDWHQDTLAAVQALTKGQILP
                     VGSSMGGWQALLLARALPERVAGLVTIAAAPDFTEDGYWANFTD"
     misc_feature    10655..10668
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 19.04"
                     /tool="antismash"
     misc_feature    complement(10762..10771)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
ORIGIN
        1 ggatggattt taccatcgcg ccaaacccgt ttctgaacct tgtcgatctg gcgcgccaga
       61 cccggcatgt gcgattgggt accggcacga tcatcgcccc attctggcat ccgatccgtc
      121 tggctggaga ggcggcgatg accgatctga tcaccgaggg gcggctggaa cttggcattg
      181 cacgcggggc ttatagctac gaatacgaac ggatggtgcc gggtatggat gcctgggacg
      241 caggccagcg gatgcgtgag ctggttccgg cgatacaggg gctatggcgg ggcgactacg
      301 cacaggaggg cacctatcat tccttcccgg ccacgacgtc ctcacccaag ccacgacagg
      361 aaaacggccc ccccatctgg gtggctgccc gcgatcccaa cagccatgaa tttgccgtcg
      421 tcaatggctg ccatgtgcag gtgacgccgc tgtggcaagg ggatgaggag atcacccggc
      481 tgatcgagac gttcaatgat gcctgcgcca aataccctga cgtgcagcgc ccggatatca
      541 tgctgttgaa ccacacctat attgcttcag atgccgccga tgcgcagcag gcggcagaag
      601 aaatcaaccg gttttactgc tacttcggcg cctggttcaa aaacgagcgc ccggtgtcgc
      661 aggggctgat tgcgccgctg agcgaagccg aaatcgcagc gcatcccttc tattcgccgg
      721 aggcgatgtt gcgtgacaat gtgatcgcca ccgccgaaga tgcgattgcc cggatccggg
      781 gatatgaggc actcgggtat gatgaataca gtttctggat cgacagcggc atgagttttg
      841 aacgcaagcg cgcctcgctt gagcggttca tccgcgatgt catgccagcc tttgcctgaa
      901 ggggatcacc atgcagcaat tccagcaata tatcggcggg gtgttctccg atggctccgc
      961 ccgttttgag agccgcgatc cggcaaccgg agaggtctgg gcgatgatgc cggaggcccg
     1021 cgcgccggat gtggacgcgg cggttgcagc cgcgtgcgcg gcattccacg cgcgggattg
     1081 ggcgggcatg accgccactg tgcgcggaaa gctgctttat cggctggcgg atctgattgc
     1141 cgagaatgct gagaccctgg cccagttgga ggcccgcgat accggtaaga tcatccgcga
     1201 aacctcggcc cagattgcct atgtggccga ttactatcgc tattacgcgg gcctcgcgga
     1261 caagatcgaa ggcgcacatc tgccgattga taaaccggat atggaggtct ggctgcgccg
     1321 cgaaccgctt ggggtggtgg cagccgtggt gccgtggaac tcgcagttgt ttctggcggc
     1381 ggtcaagatc ggcccggcac tggcggcggg ctgcactgtg gtgctgaaag cgtctgagga
     1441 agcgcctgcg ccgctgctgg aatttgcccg catctttgat caggccggtt ttccacgcgg
     1501 tgtgctcaat gtcatcaccg gatttggcgc cgattgcggc gcggtgctga cagcccatcc
     1561 tggcattgat cacatcgcct ttaccggcgg gccggacacc gcccgccatg tggtgcgcaa
     1621 ttcggcggaa aaccttgcct ccacctcgtt ggaactgggc gggaaatctc cctttatcgt
     1681 gtttgaggat gtcgatatcg acagcaccgt aaatgcccag gtctctgcca tctttgccgc
     1741 tacgggacag agctgtgttg ccggttcacg actgattatt tccaatcaga tcaaggatgt
     1801 gtttctgcgc agcctcaagg aaaaagccga gcgggtgcgg atcggtgcgc cccagatgac
     1861 ggagacggag gtcggtccac tctgcaccga cgcgcaaatg cgccggacgg tagagctggt
     1921 ggcagcgtca cttgcagcgg gtgcgcggat cgtgaccggg ggccagccgc tggaggggga
     1981 gggcaatttc tttccgccca ccatccttga ctgctccagc gcaccggacg cgccctgtct
     2041 gcgcgaggag ttttttggcc cggttctgtc ggtgtgtgga tttgacactg aggcagaggc
     2101 gctggcgctg gccaatgaca ccgcccatgg gctggcctct ggcgtgttta cccgcgacct
     2161 gacacgggcg caccggatga tccggggtat tcgtgcaggc attgtctggg tgaacaccta
     2221 tcgcgcggtc agcccgattg cgccctttgg cgggcaaggg ttgtcgggac atggtcgtga
     2281 ggggggattg caggcggcgc tggattatac aagggtcaaa acggtctggt tgcgcaccag
     2341 tgatgagccg atccccgacc cttttgtgat gcggtgacct tcagacggca gacacacagg
     2401 cgcgcgctga cagggccatt tggtggcgcg gcaggctgcg cccgagggtt aacctcggcg
     2461 cagccgtatc gcgatcattg ggggcgaatg tcgctggcca tctggcggcc atcgcgccct
     2521 tcggtcatct cgaaatcaac tttttgatta tccgccaggc cggtcagccc cgaccgctca
     2581 acctgagaga tgtgcacaaa cacatcctta ccgccgcctt cgggttcgat aaagccatag
     2641 cccttggttg tattgaacca tttcacggtg ccactcgcca tgttcccgtg tctccttcct
     2701 gctagtgagc cgccctgaat acacgataat ttcgctgcgc agagcggtgt gatcggtttt
     2761 gccgcagtgc gcagacaaaa caggccgggg aagttgtccc aacccggttc caacttttgc
     2821 acggaccatg taaaaatcaa gcaaaacagt gcggctctac cataaattgt gctgagccgc
     2881 cccctcggga aaggaaaaaa cgtgcaactc tttggattga aggcctgtga cacctgccgt
     2941 aaggcgctga aacagctgcc ggaggcggaa ctggtcgatg tacgcgccga tggcgtaccg
     3001 gaggccattc tcacagcggc tctggcgcag tttggcgacc gtctggtcaa tacccgctcc
     3061 accacatggc gcggattgag cgaggcggag cgggcggagg atcccatggc gctgcttaag
     3121 gcccatccta cgctgatgaa acgtccgcta atcaaatcag gggacgatct gcatctcggc
     3181 tgggatgcca aaaccaaggc ggcccttggc gttgagggct aggatcccca tgtcagttcc
     3241 agagtagatg aggagagcgg caatgcgcaa tgcagcgctg gtgctgggca tcgtggccgg
     3301 gctgattggg atggtggttg ggtttgcggg ttatggttat accgccgccg tggagtattt
     3361 tggcgaaatc gacgggattg cccggcaggt cgatgatgtt gatcagctgc ggcttttggc
     3421 agtgatctcg cctattctgg cgctggcggg cggtgcgatg gcgctgtccc gcgcgctgtg
     3481 gggcggggtg ctgttgcttg cgtcggcggc agggctctat gccgggttcg ggctcaatgt
     3541 ctttaccatc ttcccgatct cactggcgct tttgggcggg ctgctagcgc ttgctgccgg
     3601 caaaccggat gagccgaagg cgcatttctg acccgaggtg actaacggtc atgaaaaaag
     3661 gcgccgctgc ggatacaggg cgccttttgt gtttgagagc tcagcagatc aggcggcggc
     3721 aggtgccgtg gcgcgccgcg ccagcgcatc cagcgacagg gggccggcac ccttgaagac
     3781 gagaacgagc agcaggaatg tccacataac ccgctgatcc accagaccga tggaattgtc
     3841 aaagagactg cccagtttca caccatgccc ggtgacatcg acaatggtct gcacccagat
     3901 gaagccaatg gtgccaagcg cggccagacg ggtgaacaac ccaacaagga tcagcgcagg
     3961 cagcacgtat tcggcaatcg tcccggcaaa gatcaccagc cgctgaagga tattgagctg
     4021 ggagacatca taaagcacag cctcggcagc tttgggaaag atctgaccaa acgccccggc
     4081 agagggcgaa aagatcgacc cgtcaatctt cagcccggct gagttccagt aatagaccag
     4141 taaaacagcg gcaaagacca gcctcgccag ggtcgggatg atgaacgccg acaatctgtc
     4201 agccctgccg gtgagagagg tataagagga aacaagcgcg tgcatcggtt atcctttgcg
     4261 atctaggtca atgattgcac cgccttgcaa caacagggcg agcgtatgag agaggtcaaa
     4321 atccgggtgg tcggcctgca cctcggtcag ggcctcttcc aatgtggcac cggaggtgag
     4381 ggcggtgatc cagtccgcgc cacccggagg tagctcctga atgatggggt cgaattcggg
     4441 ccgggtgatc agcacatcct gcgccatatg ccggggcttg ggagcgttct cttcggtgtt
     4501 gaagcgccag atatcataga tcggccaggg tgagcccagc agggcaacgg cgggggccag
     4561 cgtcagccgg gtcgccatca gcgcctccgg gggcagggct gccagacgcg ccggggcaac
     4621 cgctgtggcg tcgcctgcgt gatacgcccg gcgaagggcg aggtcgagcc gcgccgcatc
     4681 gggcagatag ccgaggtgtt tcagctgctc catcccggcg agaaacgcgg gaaattcagc
     4741 gccatagtgc atcatcagcg gcgaggaggg cggatgggcg cgcaggtaca tgcccgccag
     4801 cccgtcgagg ttctgcttac ccagcagttt gccaatcagg ggaaaggcgc tgtgcatcgc
     4861 ctcggaaagg gagaccgcga tattattgcg atagacgctg aaccgccgcc cggcgggctg
     4921 gcctgtcgca tccagcagtc cctccggcac cggctggccc gcgtccatca tggcgtgggt
     4981 gaattctgtc tggcttacag tcatgccgac acgcgctcca gcgcggttgc ggcgcgggtg
     5041 gcctcggctg ccaacacagg ccagtcgggc acatcggtgt cccattcgac cagcacaggt
     5101 ttggggccgg atttcgccag cgtataatcc agcagcgccc agaccggatc caccacctca
     5161 gcgccgtggc tgtcgatcag cagcggcttg ccgtggtcgt cttcatcctc gtcatggccg
     5221 ccaaggtgga tttcaccgac ctgatccaga gcaaaggcgt cgatataacc ctgaggcgaa
     5281 aaatcgagat tggtggcgga gacaaagaca ttgttcacat ccaagagcag cccgcagccg
     5341 gtgcggcggg tgatctcggt cagaaactcc ggctcggacc agctgctctc ggcaaaagcg
     5401 aggtagctgg aggggttttc cagcagcatc cggcggccga tggtgtcctg cacctgattg
     5461 atatgatcgc agacccgcgc cagcgtggca tccgtatagg gcagcggcag cagatcgttg
     5521 taaaaatggc tgtcatgggt ggaccaggcg agatgctcag aaaaactggc gggattgagc
     5581 cagccgacca gatgtttcag ccgtgccaga tgatcggcgt ccaatggccc ttcgccgccg
     5641 atagagaggc cgacgccatg gacggagatg gcaaactgtt cgcagaggtg gcgcagctgc
     5701 gcgatcgggc ggccaccgtc gcccatgtag ttttcggcgt ggatttccag ccatttcacc
     5761 gggcctgcat cggcgaggat atcggcaaaa tgctgcggct tgtagccaac acctgtggca
     5821 gcaggcagga aaggggcggc gtccagcatg gcaggtcctc tgatccggtt acagaaaggg
     5881 cgggagacta cccccgccct cggccttaag cctttgctta tgcaggcagg tcacgctcca
     5941 gcggctccag cgagcccttg cggtcgccgc catccgccat tgcaggcagg tccatgcctt
     6001 cacagctgcc tgcgtccacc agggtccagg cgttgccttg atagtcaacg gtggaggtgc
     6061 cggcgcaggt ggtgccggga ccggcggcgc agtcattctg gccagccagg gagacgccat
     6121 agcatttctc tttggactga gcggcggctg gggtgaccat ggcagaggtc agcgcggcag
     6181 caacggcacc agcgacggcg agggattttg cagtgttgga catcggtgtc ttccttcttt
     6241 ggaatttggt tgcgaggcgg ttgttacagg tcagacatta gctcaggccg agaagtcttt
     6301 gaattcacga gcctgtgtct cacgcgggcg tcagcagctg tgaccgtata ttacaacctt
     6361 ccggctgctg aacccttaaa accatgcgca aaaagaaacc ggccccgcaa gtgggggccg
     6421 gtaaatcggt aaagatcagc aaaagaccgc agaaatgtta cagaagatcc ggcggagttg
     6481 cctcaaccgc cagtgctttt gttacagcgt ccagcgcctc gaccttggtc tgcttctcgc
     6541 caagacgccg gacggagacg gtgcgctcct cgacttcgcg gtggcccacg gccagaatga
     6601 caggcacctt gcccaccgaa tgctcgcgga ccttgtagtt gatcttctcg ttgcggatgt
     6661 cggcctcggc ccgcacaccg gcggcgcgca gggtttcaac cacttcgttc acataatcat
     6721 ccgcgtccga tgtgatggag gcgacaacca cctgacgcgg ggccagccag aacggcagct
     6781 tgcctgcgtg ttcttcgatc aggatgccaa tgaaacgttc gaaactgccc agcgtggcgc
     6841 ggtgcagcat gaacgggcga tgcttgctgc cgtcctgacc gatgaaattc gcatccagcc
     6901 gttccggcag gttgggatcc acctgcaggg tgccgcactg ccagttccgc ccaatggcgt
     6961 cggtcagggt gaattccagc ttgggaccgt aaaaggcacc ttcgccctcc agcagctcat
     7021 actcatagcc cgccgccttg caggcatcac caagcgcctt ttccaccaga tcccagcttt
     7081 catcgctgcc gatccgcttt tccgggcggg tcgagagctt gatggtccag tcatggaaac
     7141 cgaggtcggc atagactttg gacaggaaag cgatgaattt tgcagtttca gattcgatct
     7201 gatcctcggc gcagaagata tggccatcat cctgagtgaa cccacgcacc cgcataatac
     7261 catgcagcgc gcccgagggt tcatagcgcg cacaggagcc gaattcggcc atgcgcagcg
     7321 gcagatcgcg gtaggatttg aggccctgat taaacacctg cacgtggcag gggcagttca
     7381 tcggcttcag cgcgttcacg gccttttcac gggcgtgatc ctcgtcgacc tcaacgatga
     7441 acatgttttc ctggtatttg tcccagtggc ccgaggcctc ccacagtttg cggtccacca
     7501 cctgcggggt gttcacctcc acatagccgt cgcggtcctg catgcggcgc atgtagtcct
     7561 gcaaggtggt atagattttc cagccgttgg gatgccagaa gatctggccg ggtgcctctt
     7621 cctgcatgtg gaacaggttc atctcgcggc caagcttgcg gtggtcgcgc ttggcggcct
     7681 cttccagcat gtggaggtgg gctttcagct tctccttgcc ggtgaaggca acgccataga
     7741 tccgctgcag catggcgcgg tcgctgtcgc cgcgccaata ggcgcctgcg atggacatca
     7801 gcttgaaggc atcgcccggc agctggccgg tgtgctgcag gtgcgggccg cggcagagat
     7861 cctgccagtc gccatgccag tacatccgca gaggttcatc accggggatg ctctcgatca
     7921 gctcgacctt atagggttcg ttcaggtcgg tgtaatgctg gatcgcgcgg tcgcggtccc
     7981 agacctcggt ccggacttca tcacgtttgt tgatgatctc tttcatcttt ttctcgatgg
     8041 tgccgagatc ttcgggggtg aaaggctcgg cgcgatcaaa gtcgtagtac cagccgtttt
     8101 caataaccgg gccgatggtg accttggtgt cgggccagat atcctgcaca gcacgcgcca
     8161 tcacatgggc cagatcgtga cggatcagct cattggcctg ctcttcgtct ttcatggtgt
     8221 ggatggcgat ggcggcatcg gaatcgatgg gccattgcag gtcccaatgc gcaccgttca
     8281 cggtggcgga gatcgccttc ttggccagcg aggtcgagat ggacgcggcg acctcggcag
     8341 gggtgacgcc tgcgtcatag gatcgtgcat tgccatcggg gaaggtgaga gagacttggg
     8401 ccatatatcg gcactcctcg tcggtttggc gcccacagaa cgcccggttg cgggttatgg
     8461 tgttttgtcc gtttggcagg ggcgcgcgag gctgtcaagc gggcgagggg cctgccccgc
     8521 gcactccctg ggatattttg ggccagaaga tgtaaaagcc ggatcagggg cctagatcag
     8581 ggggcggggg ctggcacgcc ttcgcggatc atggctgagt agtctggcgt gatgccctgc
     8641 gcctgcgccc tggccgtaat actgccgcgt ttgcgcagct cctcggtgct gtagcctgcc
     8701 gccaataccc cctgatcatg ggcgtattcg ggcaggtagc cattggccag cacccgccag
     8761 tccagcggca cgtcctgcac gatggtgcgg atcatcgtca tcaccacggt ggtgcagttt
     8821 gaggtgagcg agttgtacca ctgcggctgt gcggccagcc ggttggcggc ctcgacatat
     8881 tgcatcagca gcgctcgggc ggtgtccgga tctgtgtcga tacgaaacag ctgcacatcc
     8941 tcgccacggg catttgtgcg ggtgcccacc acatcgcgct catcggcggc gatcagcacc
     9001 agcgtgttgg tcttgaacag atccgcgatt ggggagaaac cgccgccgac ctgacgccgc
     9061 acctcaaccg accaggcaat atgcgcaccc tcctcaaagc cgaagctgac caccatatgg
     9121 gccatctccg gccccgccca ataggacatg aagagatcta cgctgttcag ttgactgagg
     9181 tcatagctgc gggtttccca gcggggggtg aactcggttg gggtggacca gtcgaaattg
     9241 cgcacgtctg tcagcgtcag aatatcgccg tcgcgggtgc cagtgacctg ccgcgcaaca
     9301 tcgggcgacc attgcgcctc ggccggtggg gtcaggctcg cccaccacca gatcagcgcc
     9361 gcaagtgcga gacagaaggt cgaaagccca cgcagcgcgc ggccccggat caccgcccag
     9421 agggttgcca gaccgaggcc cgcaaagccg gaggccgcag ccgtacgcca gaggctgtca
     9481 accggcagcc gataccacag cgccatggcc ccccagaggg tggtcaaaag gatcagcagg
     9541 cagaggagac cgagacagaa aagacgaagg gcacggggca agggctggct cctgattgtg
     9601 gggcaaaggc gaatatcgcg cggaccctag gcagggcggc gatgggtcgc aaggctcctg
     9661 cgccggacaa aagtcgccaa atgtgaaggc gttgcctcac tgcatcttgg tgacctgtgc
     9721 cggaagggca tggggcagcg ctgaaacacg ccattgccgt ggcgccgttg ccgtggcaga
     9781 tctgggggcc tgtgatttgg caaatttttt gcgcggggga gaccatggcc gcacctcaat
     9841 ttctggacac cgatacgggc cgccgcctgg cctatcatct gacccccgca agcggcgatg
     9901 caacggcgcc gatggtggtg tttctgggcg ggctgaaatc cgacatggaa ggcaccaagg
     9961 cgatacatct ggaagcctgg accaaggcgc ggggcttggg ctttctgcgg tttgactatt
    10021 ccggccacgg tgaaagctcc ggcacgtttg aagagggctg catcggcgac tggcatcagg
    10081 acacgctggc ggcggtacag gcgctgacga aggggcaaat tctgcctgtt ggatcctcca
    10141 tgggggggtg gcaggcgctg ctcttggcgc gggccctgcc cgaacgggtg gccggtctgg
    10201 tcaccatcgc cgccgcaccc gattttaccg aggatggcta ttgggccaat ttcaccgatg
    10261 cccagaaggc ggagctggag gcacacggac aggtcgaact gccaagcgac tatatggagc
    10321 cttatgtgat caccaaacgc atgatcgagg atgggcgaaa tcatctggtg ttgcgcgatc
    10381 cgctggtgct gtcgatgccg gtgcgttgcc tgcaaggcac cgccgatacc gccgtcagca
    10441 ccgaaaccgc actgcggttg ctggatcatg ccacctgcgc cgatatgcgc ctgcaactgg
    10501 tcaaagatgc cgatcaccgg ttttcggatc ccgcctgtct ggccctgatc gaaacggctg
    10561 ttgcagaggt tctggggcta tctggcgcgg atgcgatcag ctaagctatg gggaaggcct
    10621 cgctacaggt tgcaatctaa cccgcagcag gatctgtaaa tattatgagg cctccctcgt
    10681 ttgggggccg cgggcaggag aggacgcgat ggaacaacgc atcagcctga tcaccctcgg
    10741 ggtgccggat atggagcagg ccgccgcctt ctacgaggcg cttggctggc agcgggcgga
    10801 gagccccgat ggcgtcattg cgtttgacct gatttcgcag accttgggg
//
