LOCUS       NZ_KE951483            21107 bp    DNA     linear   CON 11-DEC-2024
DEFINITION  Actinomyces graevenitzii F0530 Scaffold161, whole genome shotgun
            sequence.
ACCESSION   NZ_KE951483
VERSION     NZ_KE951483.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Actinomyces graevenitzii F0530
  ORGANISM  Actinomyces graevenitzii F0530
            Bacteria; Bacillati; Actinomycetota; Actinomycetes; Actinomycetales;
            Actinomycetaceae; Actinomyces.
REFERENCE   1  (bases 1 to 148729)
  AUTHORS   Weinstock,G., Sodergren,E., Wylie,T., Fulton,L., Fulton,R.,
            Fronick,C., O'Laughlin,M., Godfrey,J., Miner,T., Herter,B.,
            Appelbaum,E., Cordes,M., Lek,S., Wollam,A., Pepin,K.H.,
            Palsikar,V.B., Mitreva,M. and Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2013) The Genome Institute, Washington University
            School of Medicine, 4444 Forest Park, St. Louis, MO 63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: High-Quality Draft
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: Velvet v. 1.1.06
            Genome Coverage                   :: 191x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000466185.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 10:46:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,803
            CDSs (total)                      :: 1,747
            Genes (coding)                    :: 1,701
            CDSs (with protein)               :: 1,701
            Genes (RNA)                       :: 56
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 46
            CDSs (without protein)            :: 46
            Pseudo Genes (ambiguous residues) :: 0 of 46
            Pseudo Genes (frameshifted)       :: 5 of 46
            Pseudo Genes (incomplete)         :: 43 of 46
            Pseudo Genes (internal stop)      :: 4 of 46
            Pseudo Genes (multiple problems)  :: 5 of 46
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:20:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 82169
            Orig. end                         :: 103276
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KE951483.1.
            Bacteria provided by Jacques Izard, and Floyd E. Dewhirst, (The
            Forsyth Institute, Department of Microbiology, 245 First St,
            Cambridge, Massachusetts, 02142).  Funded by NIDCR DE016937 'A
            Foundation for the Oral Microbiome and Metagenome'.
            Source DNA provided by Alice Kirega, Anne C. Tanner, Floyd E.
            Dewhirst, and Jacques Izard (The Forsyth Institute, Department of
            Microbiology, 245 First St, Cambridge, Massachusetts, 02142).
            Funded by NIDCR DE016937, 'A Foundation for the Oral Microbiome and
            Metagenome'.
            The bacteria was isolated from a human subject. The phylogenetic
            relative position is available at www.homd.org.
            Coding sequences were predicted using GeneMark and Glimmer3.
            Intergenic regions not spanned by GeneMark and Glimmer3 were
            blasted against NCBI's non-redundant (NR) database and predictions
            generated based on protein alignments. tRNA genes were determined
            using tRNAscan-SE and non-coding RNA genes by RNAmmer and Rfam. The
            final gene set is processed through several programs such as Kegg,
            psortB and Interproscan to determine possible function. Gene
            product names are determined by BER. Gene names are generated at
            the contig level and may not necessarily reflect any known order or
            orientation between contigs.
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            This work was funded by the National Human Genome Research
            Institute (NHGRI)/National Institutes of Health (NIH) grant
            5U54HG00496804 for characterization of this genome.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21107
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21107
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21107
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11107](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11107
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    1581..1592
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     gene            1585..>2844
                     /gene="nuoH"
                     /locus_tag="HMPREF1978_RS01565"
                     /old_locus_tag="HMPREF1978_01118"
                     /pseudo=""
     CDS             1585..>2844
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nuoH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008734067.1"
                     /locus_tag="HMPREF1978_RS01565"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01118"
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHAVVMTLPTAAGVTADFSDTPWWITLIKAVFLAVFLILSVIMAL
                     WVERRGLGRMQTRLGPNVNGPLGLLQAVADAGKLIMKEDFWLKGAEKFIYLLAPTIAAF
                     CAFMVYAVIPFGPSVSFFGHHTPLQLTDFPVSVLYILAITAFGVYGIVLGGWSAHSTYP
                     LFGAVRSAAQVISYELAMGLSIVTVFLVSGSMSTSGIVAAQTNLWWCVGLLPSFLIYVI
                     SMIGEVNRLPFDLPEAEGELVAGHMVEYSSMKFAWFFLAEYINMFNVSAVCTTLFLGGW
                     SAGPLTLIWEGADSGWWPVLWFVTKVWACMFFMIWTRGTLVRFRYDQFMRFGWKFLIPV
                     ALAWFVLVAIVQGLRAFTDMDAQQLLLGLSVICVVTMVVLFFWPESKSGEQEPESDKFD
                     AFAGGYPVPPLPGQELPASTR"
     gene            2883..3551
                     /gene="nuoI"
                     /locus_tag="HMPREF1978_RS01570"
                     /old_locus_tag="HMPREF1978_01119"
     CDS             2883..3551
                     /EC_number="1.6.5.9"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene="nuoI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005986113.1"
                     /locus_tag="HMPREF1978_RS01570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01119"
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="WP_021603282.1"
                     /transl_table=11
                     /translation="MSKKEIDASNHDQWLRDEPSALAKLLSPLAGYGVTISSMFRPVET
                     ERYPFEKPRVMPRFHGRHQLNRYDDGLEKCIGCELCAWACPADAIYVEAAPNTPEAQYS
                     PGERYGRVYQINYLRCILCGFCIEACPTRALTMTHEIDELVGDGREGLIYEKQNLLAPL
                     PEGALAAPHPMAQGCEDGDYYRGEVSGPTQNQVDWVRANRPDDPSLATVKVVNQKEAVR
                     "
     gene            3551..4486
                     /locus_tag="HMPREF1978_RS01575"
                     /old_locus_tag="HMPREF1978_01120"
     CDS             3551..4486
                     /EC_number="1.6.5.9"
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009402145.1"
                     /locus_tag="HMPREF1978_RS01575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01120"
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="WP_021603283.1"
                     /transl_table=11
                     /translation="MATSLATALLPAPQLGLGESILFGVVAVIAVVCALGVLTAKRAVY
                     AAVNMIMIMICLATLYIANSAPFLGAVQIVVYTGAVMMLVLFVIMLVGVAADESIADTV
                     SGHKLLSSLMGLGLVVTLVTALMRSQLVGPAKFSAEIADDSIGSLAKVLFNDYSTVMEL
                     TGLLLITAALGALTLTHRESPNKRRGQAQVAKDKLEAYAKRGEHPGQKPFSGVYATTNS
                     AAAPALDASGKLLDESVSRVLRIRGQMLNTGALLPKASVPFPVETEAQVENAVHGHSGM
                     DAMNGAPAPQVSQPLAAEAETSADAAKEEK"
     gene            4483..4782
                     /gene="nuoK"
                     /locus_tag="HMPREF1978_RS01580"
                     /old_locus_tag="HMPREF1978_01121"
     CDS             4483..4782
                     /EC_number="1.6.5.9"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /GO_process="GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="nuoK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005870474.1"
                     /locus_tag="HMPREF1978_RS01580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01121"
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="WP_005986111.1"
                     /transl_table=11
                     /translation="MSLSVYVVLAVVLFSIGALTVLLRRDVIIELMGVELMLNSANLAL
                     VTFSRLHGNLDGQVFAFFVMVVAAAEVVVGLSIIVSIFKTRRSASVDDVDLLKH"
     gene            4794..6800
                     /gene="nuoL"
                     /locus_tag="HMPREF1978_RS01585"
                     /old_locus_tag="HMPREF1978_01122"
     CDS             4794..6800
                     /EC_number="7.1.1.2"
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /GO_process="GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="nuoL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005986110.1"
                     /locus_tag="HMPREF1978_RS01585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01122"
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="WP_021603284.1"
                     /transl_table=11
                     /translation="MNFTPLAVQASSQDVLAVPATGLLAYAWLLIAVPAASAALLLVLG
                     RRSDKWGHWLALAAAGFDACFGLTLIWKLLSLPASQRVTDHHLWRWFSAGKWELDLGVR
                     VDPLSLTFVGLVTFVGFLIHVYSVAYMSHDRDRRRFFAYLNLFVAAMLTLVLGNSYLAL
                     FVGWEGVGLASYLLIGFWNTADADAPDAVKATSAKNAVAAKKAFVMNRVGDMGLLAAMM
                     AMMSVVGSVDFDAVLPAATTGAVSTGWLTVIGLFLLVAACGKSAQFPLQAWLGDAMAGP
                     TPVSALIHAATMVTAGVYLMVRSGAIYQGAPDAQLAVAIIGAITLLFGAIVGCAKDDMK
                     KVLAASTMSQIGYMMLGAGLGPIGYAFAIFHLLTHGFFKAQLFLGAGSVMHAMSDQVNM
                     RRFGNLRTAMKITWITMGIGWIAILGLPPFSGFFSKDKIIEAAFVGEGVRPWILGSIAL
                     IGAGITAFYMSRLFFMIFHGKARWTTEADLEGPVHPHESSPWMTVPMIILSVFSVGLGG
                     ALSYGNAFTNWLTPVVGHHEHGEPVLAIPVIMAATLILVVAGVALAWVMYVRRPVATVV
                     QPSNVLVEAARHDLYQDNLNEAVAMRPGKALADGADRSDRYVIDGVIAALVATVKGSGK
                     AVTAAQNGYARSYAAYMLVGVVALLIALVAAQI"
     gene            6814..8361
                     /locus_tag="HMPREF1978_RS01590"
                     /old_locus_tag="HMPREF1978_01123"
     CDS             6814..8361
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005986109.1"
                     /locus_tag="HMPREF1978_RS01590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01123"
                     /product="NuoM family protein"
                     /protein_id="WP_021603285.1"
                     /transl_table=11
                     /translation="MYTSVINASFPVLSIAAAVPMLGALLLWLVPATRRQAKLLGMVFS
                     LVTLGLAGHMLANYDYSATDKLQFAQSGSWIPMFGVSWSLALSPISLAMVVLALALVPL
                     VLIAARSDVSEAQLGGFTGHVLALESFIVVIFSAQDLFVFYLAFEAMLIPVYFLIGNYG
                     GPQRRRAAMKFLLYSLAGGLVMLVAVAIVGVHAYGNPEGFTFTQMAATYKELGQSERTI
                     MFICLLVPFIIKAPMVPLHTWLPDTAEQATPGTSVLLIGVLDKIGTYGMIVMCVPLLTS
                     DMHWVSLTMMSLAIVAIIYGGLAAIVQDHLYRLISYTSVSHFGFMVLGIFGGSIAGASG
                     AMVYMVAHGLSIAGLYLISGFLVRRTGTARLSEMGGIARVSPVIAGTFLFSALASIALP
                     GLSGFVPEWLVLTGTFSVSTAAGLFALLGVVIAALYALWPYQKVFTGAPKEKYVGIGDL
                     NKSEKLLVTPLLIAMLALGLFTAPLTNLLAEQAELISAYTGQPGQVSVVLSQGGEAK"
     gene            8358..10004
                     /gene="nuoN"
                     /locus_tag="HMPREF1978_RS01595"
                     /old_locus_tag="HMPREF1978_01124"
     CDS             8358..10004
                     /EC_number="7.1.1.2"
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /GO_process="GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="nuoN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005986108.1"
                     /locus_tag="HMPREF1978_RS01595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01124"
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="WP_021603286.1"
                     /transl_table=11
                     /translation="MNETAATAAQFNWAALAPALAVALTAVLGVLVEALVPRAWRPTTQ
                     RVLAVAGVAVAIVLATVRWLDTLTPTKEVVNQVNVGQLDLSSVAYGSIAPGLVEDRFSQ
                     AASLILLVIGLLSVFLLADRTSARDGAIAAQAADRPGSAEEAQSLHLGWQTTEVYPLTL
                     LSLSGMMLFANVNNLAALFVVLEIISLPLYVLSATARHRRLLSQEAALKYFILGAFASG
                     FLLFGSALIYGVYGVLDYSLLAKGMTRWAQVGAPGLLVPVGVILIVVGLLFKIAAVPFH
                     SWSPDVYQGAPTPVTAFMASGVKAAAFFALCRFAFTAGLYPLFSKAATSQVLYWSLWVI
                     AIATMLVGTVGGVLQKDIKRMLAYSAISHAGFMLIAIIGAQAVSLTAIALYSLVYGLAT
                     IAAFGVVSLVRRSHNGISAEANEIASYAGLGKTNPMLAAAMALALLSFAGIPLTAGFVG
                     KFQLFVTAASGNTLWLVVAAVVCSAITAFYYVRVISNMFFRKPAQGVEVVVSDGFALVA
                     IFAAVVGTIFLGVYPQPVMHWLSQVAVMLVP"
     gene            10001..11107
                     /locus_tag="HMPREF1978_RS01600"
                     /old_locus_tag="HMPREF1978_01125"
     CDS             10001..11107
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009747773.1"
                     /locus_tag="HMPREF1978_RS01600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01125"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_021603287.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2e-54, bitscore:
                     177.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSALQLDVPELEEIIVPQLDEVEARLMEVVSNADETINPPTSHL
                     AAAGGKRLRPMLVLLTAQLGDAAAACSQQVHDAAVAVELTHIATLYHDDVMDDAPKRRG
                     APSAQMVWGNSAAILTGDILVARASQMVAALGPDAVLAHARTFERLCTGQLHETLPRPE
                     GVDPVDHYIQVLADKTGSLIALCGLYGTMLTGAGAKAQRIVELYGEKIGVAFQLADDVI
                     DICSDSETTGKTPGTDLLEGVDTMPVLLLRQRLASGELDSAGQAILSLLSTGNLQRQQV
                     LSDVVQRLRNHPVTAETRAMAGAWCDEAVAALADLDDAVVEATRTRLEAEGLSEAEVTQ
                     GVESARSRAQLVRRGLEDFAHLLVDRAA"
     assembly_gap    11206..11305
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            11426..12892
                     /locus_tag="HMPREF1978_RS01605"
                     /old_locus_tag="HMPREF1978_01126"
     CDS             11426..12892
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285: ferredoxin fdxC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005986105.1"
                     /locus_tag="HMPREF1978_RS01605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01126"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_034477890.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.5e-12, bitscore:
                     38.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALNVAVIGAGPAGIYASDILSKSGLDVNIDLFERLPAPYGLVR
                     YGVAPDHPRIKQIIVALYKILQRGDIRLIGNVEVGRDVSVAELHEHYDAIIFSTGADTD
                     APLNIPGADAPECYGGADFVSWYDGHPDHPRTWPLEAKEVAVLGVGNVGLDISRVLAKH
                     AEDLMVTEIPENVAEILKTNPCTDVHVFGRRGPAQVKFTPLELRELGKQRDVDVLVDEA
                     DFEYDAGSEAALKSSNQQRQVVKALEGYAMQEPEELTASHRIHIHLFQSPAEVLTDDAG
                     HVVGLRTERTRLTGDGTVEGTGVFTDWPVQAVYRAIGYASSPIEGMPFDSKRHVIPNEG
                     GRVLGEDGKPLTGMYATGWIRRGPIGLIGSTKSDAQETITNLVADANAGLLHATTDAVG
                     HDAMIALLSSRDIPFTTWEGWELLDAYERQLGEDFGELPNGKTRERVKVVNRHAMADIS
                     RGKQAPQDLIGQPDTDRVPERVAHRLPAQD"
     gene            complement(13100..14350)
                     /locus_tag="HMPREF1978_RS01610"
                     /old_locus_tag="HMPREF1978_01127"
     CDS             complement(13100..14350)
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005986103.1"
                     /locus_tag="HMPREF1978_RS01610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01127"
                     /product="DNA recombination protein RmuC"
                     /protein_id="WP_021603289.1"
                     /transl_table=11
                     /translation="MSIVNAIALLLLGITLGTALGWALATARAARLAANGGEVARIRAD
                     AAGASARAQALEQQLRTEQQRTLEAQQRARQDGAVLTALEPVREQLEHMALRVEQMELQ
                     RSKQNAIIAERLRASDATQERLRASTASLESALRSRSARGMWGEMELRRVLELGGMSEH
                     IDFELQKSVSTLRKQNRAGSLNAAPSPANGSARPDATILLPGGEFLAIDAKAPLDAFLR
                     GADAGAKGDQDAANSYLSDHAAAVRSHINELIRRNYPEQLGQGPQFTIMFIPSEAVLSA
                     ALEVDASLLEYALANGVLLTTPISLLAVARTVADAWMQNAINDDARQLLAIGSTLYKRL
                     GTVARYMDDLGASLRRSVQTYNKTVNSIEKNLLSTAKGLENLGNTLTSPSPIASEAAQI
                     RSFSAPELTNPDLEGPR"
     gene            14486..15265
                     /locus_tag="HMPREF1978_RS01615"
                     /old_locus_tag="HMPREF1978_01128"
     CDS             14486..15265
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.5"
                     /locus_tag="HMPREF1978_RS01615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01128"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_021603290.1"
                     /transl_table=11
                     /translation="MTNACYRFVVKLDRNLGVVLEYRAGTVQDLDVLARIGADAFSDYP
                     LFRLTEPELRPGVTFDQFHFALHRMLVKIFLKRESVLVACEDGKPRGYALLQKQEMPFL
                     PYLLNGGVGLLKYIPLKPLLEFLTLTDAADQHVKLNTHYDWFLEVIAVHPEHQGRGIGT
                     GMLDVGIAKFVKATGGSNYAFVTNTAKNARFYDHNGCRELAVSHLDYRGQEINVWAFKK
                     ELDKKKSKPAKDAKAGAKDAKAANEAKPAKNTEETGK"
     misc_feature    14497..14514
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            15300..16385
                     /gene="ychF"
                     /locus_tag="HMPREF1978_RS01620"
                     /old_locus_tag="HMPREF1978_01129"
     CDS             15300..16385
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ychF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010614409.1"
                     /locus_tag="HMPREF1978_RS01620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01129"
                     /product="redox-regulated ATPase YchF"
                     /protein_id="WP_021603291.1"
                     /transl_table=11
                     /translation="MALTIGIVGLPNVGKSTLFNALTRATVLAANYPFATIEPNVGIVP
                     LPDARLDKLAQIFGSERILPATVSFVDIAGIVRGASEGEGLGNQFLANIREADAICMVT
                     RAFDDPDVVHVDGKVEPSSDIETISTELVLADIQTLEKAIPRLEKEVRGKKTDPAVLQT
                     AKDALKVLEEGTMLSAGAKAAGLDTDILRTFQLMTTKPFIYVFNMDDAGMHDEAKQAQL
                     RELVSPAEAIFLDAQFESELVELEPAEASEMLADNGQAESGLDQLARVGFKTLGLQTYL
                     TAGPKEARAWTIHQGWTAPQAAGVIHTDFERGFIKAEIVSFDDLVEYGSVAEARAHGKV
                     RMEGKDYVMADGDVVEFRFNV"
     gene            16542..16823
                     /locus_tag="HMPREF1978_RS09190"
                     /old_locus_tag="HMPREF1978_01130"
     CDS             16542..16823
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005936145.1"
                     /locus_tag="HMPREF1978_RS09190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01130"
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_021603292.1"
                     /transl_table=11
                     /translation="MIQSFGDRQTERLFAREAVPSLDSRIARVALRKLRQIDAACRLED
                     LRVPPGNRLEHLRGDRAGQYSIRINDQWRICFRWGDAGPEGVEIVDYH"
     gene            16750..17118
                     /locus_tag="HMPREF1978_RS01625"
                     /old_locus_tag="HMPREF1978_01131"
     CDS             16750..17118
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003780577.1"
                     /locus_tag="HMPREF1978_RS01625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01131"
                     /product="HigA family addiction module antitoxin"
                     /protein_id="WP_081688319.1"
                     /transl_table=11
                     /translation="MISGVSASGGATLVQKGLRSLTTTKIAPIHPGEVLMEDFIEGFGI
                     TQHKLAVAIDVPPRRINEIVHGKRGITADTAMRLSRYFGTTPGFWMNLQMRYELDRAED
                     VLGDRLSGIVPLTMVEVA"
     gene            complement(17215..17856)
                     /locus_tag="HMPREF1978_RS01630"
                     /old_locus_tag="HMPREF1978_01132"
     CDS             complement(17215..17856)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016668718.1"
                     /locus_tag="HMPREF1978_RS01630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01132"
                     /product="hypothetical protein"
                     /protein_id="WP_021603294.1"
                     /transl_table=11
                     /translation="MRSVSTPLNRCVLAICGFVLLAASAWLLASGLGLARFWPDAAPYL
                     ASKQGRVGAVASQANWLLPVLALASVLAIIGGLALLLMQVPRRVAASPMRLSDSEGLLL
                     TTLDPEVLSQALSERAQGVPGVERCTVWVSGTLSHLQIQADASVSQECEIDWTVSTLRS
                     RLQQDVSISLGYEPKQIDLLVRLERPTSSKVLRTASSQGSPKPAKDTDAA"
     gene            complement(17869..18414)
                     /locus_tag="HMPREF1978_RS01635"
                     /old_locus_tag="HMPREF1978_01133"
     CDS             complement(17869..18414)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005986074.1"
                     /locus_tag="HMPREF1978_RS01635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01133"
                     /product="DUF6286 domain-containing protein"
                     /protein_id="WP_021603295.1"
                     /transl_table=11
                     /translation="MRKVPKLIRRPSRSGSSVVLALLLLAGGSLGAWLTGQRLITGYWP
                     RHALHALEAIKSTSLSSTAALIAAGVVAACGLIMIIAALWPGRPERVEILPDDIPGQTA
                     VRRRDLAKLVRLQVEQLGGANSVSATARRSRVNVVVHSVLDELEPVQQAAQKQTDQALQ
                     MLAPVGIKGSRVRVKHAS"
     gene            complement(18411..18872)
                     /locus_tag="HMPREF1978_RS01640"
                     /old_locus_tag="HMPREF1978_01134"
     CDS             complement(18411..18872)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005986073.1"
                     /locus_tag="HMPREF1978_RS01640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01134"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_021603296.1"
                     /transl_table=11
                     /translation="MASLASPTATQSSGLQPTTGQAGQRGTAQAADTDAGTAQRGSTTI
                     PAKVVAKIAAEAAYETGNVGSNAGGVLGIGARRNFSSRPDAQCELYGQVAVLHMNLGLV
                     FPTPLADTIEAVRAHVRSRVEHLTGLSVGKINIEISWLNPDGPGRKNLK"
     gene            complement(18875..19051)
                     /locus_tag="HMPREF1978_RS09810"
                     /old_locus_tag="HMPREF1978_01135"
     CDS             complement(18875..19051)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009234222.1"
                     /locus_tag="HMPREF1978_RS09810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01135"
                     /product="hypothetical protein"
                     /protein_id="WP_005986071.1"
                     /transl_table=11
                     /translation="MKTTHLALLVGLFLGTVLAFGSFADFVLVSLCGLVGLGVGLYLEG
                     RVDVRSFLERLRK"
     gene            complement(19078..19530)
                     /locus_tag="HMPREF1978_RS01650"
                     /old_locus_tag="HMPREF1978_01136"
     CDS             complement(19078..19530)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005986069.1"
                     /locus_tag="HMPREF1978_RS01650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_01136"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_034477896.1"
                     /transl_table=11
                     /translation="MSDTSKQPEQNENTEAGSTPNTPLHTSHGVTTIDENVIAKIAGMA
                     TREVPGVYSMGNAMRRAFTAMTERIPTAQTNVTGGINVQKGETQTSIEVTVVVDYGAPI
                     IEVTEAIRNNIIEQIETSTGLEVVEVNIHVTDVHLPGDESETNNLK"
     misc_feature    complement(20522..20536)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    20636..20648
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     misc_feature    21079..21097
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.02"
                     /tool="antismash"
     misc_feature    complement(21080..21098)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.61"
                     /tool="antismash"
ORIGIN
        1 tggatcaccg acaaggaccg cttcgccttc ccgtgggcca gcgctccgga ccgcctgacc
       61 accccgctgg tacgtgaagc tgacggcacc ctggttccca ccagctggcc cgacgctctc
      121 gacgtcgccg cacgcggcct agctaaggcc atcgccgctg gtggcgtggg tttcctaccc
      181 ggcgcccgac tgaccctaga ggacgcttgg gcctggtctc gctttgcccg caccgtggcc
      241 cacaccaacg acatcgacca gcgagtacgt cccgccggcg ctgaggatga agctttcatc
      301 gccgctaacg tggctggtcg cggccttggc cgcgtcacct acaccagcct ggaaagcgcc
      361 ggcacggtgc tgctggtggc cctagagccc gaggatgagt gtggttcgct gttcctgcgc
      421 ctacacaagg ccgtgaacaa ccgtggcctc aaggtgcaca ccgtggctcc gattaagagc
      481 gccggttcgg taaagctacg tgccaacatc atcagcgcca cccccggtag cgaggttgcc
      541 gctgttaagg ccctgcccgc cgagctaacc gaggccctta gcgctgaggg tgccaccatc
      601 ctggtgggtg aacgcgctgc cgaggtgccc ggcctgctca gcgccgtcga cgctttggct
      661 aagagcaccg gtgcccgtct ggcttgggtg ccgcgccgtg ccggtgaacg cggtggtatc
      721 gaggctggta ccctgccggg cctgctgcct ggtggtcgcc tagtttccga cgacgccgcc
      781 cgcgcccagg ttgagcagct atggggcgcc ctgcccgctg ctgccggccg cgacactgag
      841 gccatcctta actcggtgct cagcgccgac ggcctagacg ccctggtagt tggtggcgtt
      901 gacctgcgcg actttagtga cccgggactg gcccgcaccg ccatgagcga agctggcttc
      961 ctggtacagc tagaggtgcg tcgctcagaa atcagcgagc acgccgacgt tatcttcccc
     1021 gtggccccgc ccgtggaaaa gaacggcacc ttcgttaact gggaaggccg cgtacgtccc
     1081 ttcggccagg cccacgtttc acgcgcccgc accgaccgtc aggtactggc catgctggct
     1141 gcagaaatgg gatctgacct gcacgtaaat gacctagctg agctacaccg tgagctagcc
     1201 ggcctgggca ttagcgcaac gcaccctgac atgcagccca ccagcgccgt cgccactagc
     1261 aaactggccc ccgggcaggc ctacctggcc acccacaagc ccatgcttga cggcgggcgc
     1321 ctacaggact tcgaagagca cctggccgcc accgcgcgcc gcccggtggt ctacgtggcc
     1381 cgcgaactgg ccaaggctaa tggcatccac tccggcagcc agctgcaagt cagcacgcaa
     1441 accggctcga tcactttgcc ggcggtaatc gcgccgctag cacccaacac tgtttggctt
     1501 cccgaatgct cggccggttc caccgtgcgt cagagcctag gcggcggcca aggtcttatc
     1561 gttaatctct cggaggtgaa gtaaatgcac gccgtcgtta tgacgctgcc aaccgcagcc
     1621 ggggtaactg cggacttttc tgacaccccc tggtggatta cgctgatcaa agccgtattc
     1681 ctagcggtat ttttgatcct gtccgtgatt atggcgctgt gggttgaacg tcgcggcctg
     1741 ggccgtatgc agacccgtct agggcctaac gttaacggtc cgctaggtct gcttcaggct
     1801 gttgccgacg caggcaagct gatcatgaag gaagacttct ggcttaaggg cgccgaaaag
     1861 ttcatctacc tgctggcccc caccattgcc gccttctgtg ccttcatggt ttacgcggtg
     1921 atcccctttg ggccttcggt gagcttcttt ggtcaccaca ccccgctgca gctaactgac
     1981 ttcccggttt cggtgctcta catcctggct attaccgcct ttggtgtgta cggcattgtg
     2041 ctaggtggtt ggtccgccca ctccacctac ccgctgtttg gtgcagtgcg tagcgccgcc
     2101 caggtgatca gctacgagct ggccatgggt ctgtccattg tgaccgtgtt cctggtttcg
     2161 ggctccatgt ccacttccgg gattgtggcc gcacagacca acctgtggtg gtgtgtgggc
     2221 ttgctgccca gcttcctgat ctatgtcatc tccatgattg gtgaagttaa ccgtctgccc
     2281 ttcgaccttc ctgaagctga aggtgagctg gtggctggac acatggtgga gtactcctcc
     2341 atgaagttcg cctggttctt cctggccgaa tacatcaaca tgttcaacgt ttccgccgtg
     2401 tgcaccacct tgttcctagg tggctggagc gccggcccgc taaccctgat ttgggaaggc
     2461 gccgactctg gctggtggcc ggtgctgtgg ttcgtaacca aggtgtgggc ctgcatgttc
     2521 ttcatgattt ggacccgtgg tactttggtg cgtttccgct acgaccagtt catgcgtttt
     2581 ggttggaagt tcctgattcc ggtggctctg gcctggtttg tgctggtggc tattgtgcag
     2641 ggcctgcgcg ccttcaccga catggacgca cagcagctgc tgctgggtct aagcgtgatc
     2701 tgcgtggtga ccatggtggt gctgttcttc tggcctgaat ctaagtccgg tgaacaagag
     2761 cctgaaagcg acaagtttga cgctttcgcc ggtggttacc cggtcccgcc gctgcccggg
     2821 caggaactac ctgcctctac ccgtcacgcg gtgcccgcca agtctgccaa ggaggttgaa
     2881 aagtgagtaa aaaagaaatt gatgcctcca accacgacca gtggctgcgt gacgagcctt
     2941 cggcgctagc taagctgctc tcgcccctgg ctggctatgg ggtaactatt tcctccatgt
     3001 tccgtccggt ggaaactgag cgttacccct ttgaaaagcc ccgggttatg cctcgcttcc
     3061 acggccgtca ccagctcaac cgttacgacg acgggctgga aaagtgcatt ggttgtgaac
     3121 tgtgtgcttg ggcttgcccg gctgacgcta tctacgttga ggccgccccc aacactcccg
     3181 aggcgcagta ctctcccggt gagcgctacg ggcgtgtcta ccagatcaac tacctgcgct
     3241 gcattttgtg cggtttttgc attgaggctt gtcctacccg tgcactaacc atgactcacg
     3301 aaattgatga gctggtaggt gacggccgtg aaggcctgat ctatgaaaag caaaacctgc
     3361 tagctccctt gcctgaaggt gccctagctg ccccgcaccc gatggcgcag ggctgcgaag
     3421 acggtgacta ctaccgtggc gaggttagcg gccccaccca gaaccaggtg gattgggtac
     3481 gtgccaaccg tcccgatgac cccagcctgg ccaccgtgaa agtcgtaaac cagaaggagg
     3541 ctgtgcgcta atggcaactt cactagccac cgcccttttg cccgccccgc agctgggctt
     3601 gggtgaaagc atcctgtttg gggtagtcgc cgttattgcg gtggtgtgcg ccctgggcgt
     3661 gctaaccgct aagcgtgcgg tctacgcggc cgtaaacatg atcatgatca tgatctgttt
     3721 ggccaccctt tacattgcta actctgcccc gttcctggga gcagtgcaga ttgtggtcta
     3781 caccggtgcg gtcatgatgc ttgtgctatt cgtgatcatg ctggtgggtg tggccgcaga
     3841 cgagtccatt gccgacactg tcagtggaca caagctcctc tccagcctga tgggcttggg
     3901 tttggtagtc accctggtga cggcgctgat gcgttcgcag ctggtggggc cggccaagtt
     3961 ctcagctgaa attgctgacg actccattgg ttctctagcc aaggtgctgt tcaacgacta
     4021 ctccacagtt atggagctaa ccggtctgct gctaatcacc gcagccctag gcgcgctgac
     4081 cctaacccac cgcgaaagcc ccaacaagcg tcgcggtcag gcacaggttg ctaaggacaa
     4141 gcttgaggcc tacgccaagc gcggcgagca cccgggtcaa aagcccttct ccggtgtcta
     4201 cgccaccacc aacagcgctg ccgccccggc gctggacgcc tccggcaagc tgcttgacga
     4261 gtcggtttcg cgcgtactgc gtattcgtgg ccagatgcta aatactggcg cactgctgcc
     4321 taaggccagc gtgcccttcc cggtggaaac cgaggcccag gttgaaaacg cggtacacgg
     4381 ccactccggt atggacgcca tgaatggcgc cccggccccg caggtgagcc agcctctggc
     4441 cgctgaagcc gaaactagcg ctgacgctgc taaggaggaa aagtgagcct aagcgtttac
     4501 gtagtcctgg ccgtggtgct ctttagcatt ggtgcgctca ccgtgctgct gcgccgcgac
     4561 gtgattattg aactaatggg ggttgagctg atgcttaact cagctaacct cgccctggtt
     4621 accttctcac gtctgcacgg caaccttgat ggccaggttt tcgccttctt tgtgatggtg
     4681 gttgccgcag ctgaagttgt ggtggggcta tcgattattg tgtccatctt taagacccgc
     4741 aggagcgcat ctgttgatga cgttgacctg ctcaagcact gagaggaaaa ccggtgaact
     4801 ttactcctct cgcagtacaa gcctctagcc aggatgtgct agccgtgccc gctacaggtt
     4861 tgctggccta cgcctggctg ctaattgctg tcccggccgc tagcgccgcc ctgttgctgg
     4921 tgctgggacg ccgcagcgac aagtggggcc actggctggc tctggccgca gctggttttg
     4981 acgcctgctt tgggctaacc ctgatctgga agctactaag ccttccggct tcccagcgcg
     5041 taaccgacca ccacctgtgg cgttggttca gcgccggcaa gtgggagcta gacctgggcg
     5101 tgcgcgttga cccgctgtcg ctgaccttcg tgggcctagt taccttcgtg ggtttcctaa
     5161 tccacgttta ctccgtggcc tacatgtccc acgaccgcga ccgtcgtcgt ttcttcgcct
     5221 acctgaacct gttcgtggca gccatgctca ccctggttct gggtaacagc tacctggccc
     5281 tgtttgtggg ttgggaaggc gtgggcctgg cttcctacct gctaattggt ttctggaaca
     5341 ctgccgacgc cgacgctccc gacgccgtaa aggccaccag tgccaagaac gccgtcgccg
     5401 ccaagaaggc cttcgtaatg aaccgtgtcg gtgacatggg tctgctggcc gccatgatgg
     5461 ccatgatgag cgtggtgggc tcggttgact tcgacgccgt cctgcccgcc gccactacgg
     5521 gtgccgtatc caccggctgg ctgaccgtta tcggcctgtt cctgctggtg gcagcctgtg
     5581 gtaagtctgc acagttcccc ctgcaggcct ggctgggtga cgccatggct ggccccaccc
     5641 cggtgtcggc cctgatccac gcggccacca tggttaccgc cggtgtgtac ctaatggtgc
     5701 gctcgggcgc tatctaccag ggtgcccctg acgcccagct ggccgtggcc atcattggtg
     5761 ccattacgct gctgttcggt gccattgtgg gttgcgccaa ggacgacatg aagaaggtac
     5821 tggccgcctc caccatgagc cagattggtt acatgatgct gggcgcgggc ctaggcccca
     5881 tcggctacgc cttcgctatc ttccacctgc tcacccacgg cttcttcaag gcccagctgt
     5941 tcctgggtgc cggtagcgtc atgcacgcta tgagcgacca ggtcaacatg cgtcgctttg
     6001 gtaacctgcg caccgccatg aagatcacct ggatcaccat gggtatcggc tggatcgcca
     6061 tccttggttt gccgcctttc tccggcttct tctccaagga caagatcatt gaggccgctt
     6121 ttgtgggtga aggtgtgcgc ccgtggatcc tgggttccat tgccctgatc ggcgctggaa
     6181 ttaccgcttt ctacatgtcg cgtctgttct tcatgatttt ccacggcaag gcccgctgga
     6241 ctactgaagc tgacctggaa ggcccggtcc acccgcacga gtccagcccc tggatgaccg
     6301 tccccatgat catcttgtcg gtgttctcgg tgggtctagg tggcgcgctc agctacggta
     6361 atgccttcac taactggctc accccggtag ttggccacca cgagcacggc gagccggttt
     6421 tggctattcc ggtgatcatg gctgccacct tgatcctggt agtggccggt gtggctctgg
     6481 cttgggtgat gtatgtgcgt cgcccggtag ccactgtggt tcagccttcc aacgttctgg
     6541 ttgaagctgc acgtcacgac ctataccaag acaacctcaa tgaggctgtg gccatgcgcc
     6601 cgggtaaggc cctggctgat ggtgctgacc gctctgaccg ttacgtcatc gacggcgtca
     6661 ttgccgccct agtggccacg gttaagggtt ctggtaaggc cgttactgct gctcaaaacg
     6721 gttacgcgcg ttcctacgcc gcttacatgc tggtgggggt tgtcgccttg ttgatcgccc
     6781 tcgtcgccgc ccaaatttga cgggaagatg taaatgtaca cgtcagtaat taacgcttca
     6841 ttcccggtgc tttccatcgc ggcggcagtg cccatgctgg gtgcgctcct actgtggtta
     6901 gtgcctgcaa cccgccgcca ggctaagctc ctgggcatgg tgttctcgct ggtaacccta
     6961 ggtttagctg gtcacatgct ggccaactat gactactcgg ctaccgacaa gctacagttc
     7021 gcccagtccg gcagctggat ccccatgttc ggggtgagct ggtcgctggc gctaagcccg
     7081 atctcgctgg ccatggtggt gctagccctg gccctagtgc cgctggtact tatcgccgct
     7141 cgctctgatg tgagcgaagc tcagctaggc ggtttcaccg gacacgtact ggctctggaa
     7201 tcgttcattg tggtgatttt cagcgcccag gacctattcg tcttctacct ggctttcgaa
     7261 gctatgctga tcccggtcta cttcctgatc ggtaactacg gcggccccca gcgtcgtcgt
     7321 gcagctatga agttcctgct ttactcgctg gccgggggac tggtcatgct ggtggcggta
     7381 gctatcgtgg gtgtgcacgc ctacggcaac ccggagggct tcaccttcac ccagatggct
     7441 gccacctaca aggagctagg ccagagtgaa cgcaccatca tgttcatctg cctgctggtg
     7501 ccgttcatca tcaaggcccc catggtgccg ctgcacactt ggctgcctga caccgccgag
     7561 caggccaccc cgggcacatc cgtgctgctg atcggtgtgc tggacaagat cggtacctac
     7621 ggcatgatcg tgatgtgtgt gccgctgctg accagcgaca tgcactgggt ctcgctgacc
     7681 atgatgagcc tggcgattgt ggccattatt tacggtggtt tggccgccat tgtgcaagac
     7741 cacctgtacc gcctgatttc ctacacctcg gtaagccact tcggtttcat ggtgctgggt
     7801 atcttcggtg gatcgattgc tggtgccagt ggcgccatgg tttacatggt ggctcacggc
     7861 ctgtcgatcg cgggcctgta cctgatctct ggtttcctgg tgcgtcgcac cggcaccgcg
     7921 cgcctgtccg agatgggcgg tattgcccgc gtcagcccgg ttatcgccgg taccttcctg
     7981 tttagcgccc tggcttcaat tgcactgccg ggcctgagcg ggtttgtgcc tgagtggctg
     8041 gtgctcaccg gtaccttctc agtctcgacg gcggccggcc tgttcgccct gctgggtgtg
     8101 gttattgcgg ctctgtacgc gctatggccc taccagaagg tgttcaccgg tgcgcccaag
     8161 gaaaagtacg tgggtatcgg tgacctgaac aagagtgaaa agctgctggt taccccactg
     8221 ctgatcgcca tgctggcgct gggtctattt actgcgccgc taactaactt gctagccgaa
     8281 caagccgagc tgatcagtgc ctacaccggc cagcccgggc aggtttcggt agtcctgtcc
     8341 cagggagggg aagccaagtg aacgaaactg ctgctaccgc agcccaattt aactgggctg
     8401 ccttggcccc cgcactagcg gtggcgttaa ccgcagtcct cggggtgctg gttgaagccc
     8461 tagtgccgcg cgcttggcgc cccaccactc agcgagtact ggctgtggcc ggtgtcgcgg
     8521 tggcgattgt gctggccacg gtgcgttggc tagacaccct cacccccacc aaagaggtgg
     8581 ttaaccaggt aaatgtgggc cagcttgact taagctcagt ggcttacggg tctatcgccc
     8641 caggcctggt ggaggaccgc ttctcgcagg cagcctccct gattttgctg gtgatcggcc
     8701 tgctcagcgt gttcttgctg gccgaccgca ctagtgctcg cgacggcgcc attgccgccc
     8761 aggccgctga ccgtcccggt agtgctgagg aagctcagtc cctgcacttg ggttggcaga
     8821 ccaccgaggt ttacccgctg actctgctga gcctaagcgg catgatgctg tttgctaacg
     8881 taaacaacct ggcggcactg tttgtggtgc tggagattat ctccctgccc ctgtacgtac
     8941 ttagcgccac cgcccgccac cgtcgcctgc tcagccagga agcggccctg aagtacttca
     9001 tcttgggtgc ctttgcctcc ggtttcctac tgtttggttc cgcgctgatt tacggtgttt
     9061 acggcgtgct ggactacagc ctgctagcta agggcatgac ccgctgggcc caggtaggcg
     9121 cgcctggcct gctggtgccg gtgggcgtga tcttgattgt ggttggtttg ctgttcaaga
     9181 ttgcggcagt gcccttccac tcttggagcc cggacgtata ccagggtgcc cccaccccgg
     9241 ttaccgcctt catggctagt ggggttaagg ctgctgcctt cttcgccctg tgccgtttcg
     9301 ccttcactgc tgggctgtac ccgctgttct ctaaggctgc caccagccag gtgctgtact
     9361 ggtcgctgtg ggtgattgcg attgccacca tgctggtagg taccgtcggt ggtgtactgc
     9421 aaaaagacat caagcgcatg ttggcctact cggctatctc gcacgccggc ttcatgctga
     9481 tcgccattat tggggcccag gcagtttcac tgaccgcgat cgccctgtac tcgctggttt
     9541 acggtctggc taccatcgcc gccttcggtg tggtcagcct ggtgcgccgt agccataacg
     9601 gcatcagcgc tgaagctaac gagattgcca gctacgccgg tttgggtaag accaacccga
     9661 tgctggctgc cgctatggcc ctggcactgc tgtccttcgc cggtatcccg ctgaccgccg
     9721 gttttgtggg taagttccag ctgtttgtca ccgccgcctc gggtaacacc ctgtggctgg
     9781 ttgtggccgc agtggtgtgc tcggcgatca ccgcgttcta ctatgtgcga gttatctcta
     9841 acatgttctt ccgcaagccc gcccagggcg tggaggttgt agttagcgac ggctttgccc
     9901 tggtagctat cttcgcagct gtggttggca ccatcttcct aggcgtatac ccgcagccgg
     9961 ttatgcactg gcttagccag gtagccgtta tgctggttcc gtgagtagcg cattgcagtt
    10021 agacgttcca gagctagagg aaattattgt tcctcagctt gatgaggtag aggcgcggct
    10081 gatggaggta gtctccaacg ctgacgagac catcaacccg cccacctcac acctagctgc
    10141 cgctggtggt aagcggctgc gtcccatgct ggtgctgctt acagcccagt taggcgacgc
    10201 cgccgcagcc tgctcacagc aggtgcatga tgcggctgtg gccgtggaac tgacccatat
    10261 cgccaccttg taccacgacg acgtcatgga cgatgccccc aagcgtcgcg gggcgccgtc
    10321 ggcacagatg gtgtggggta actcagctgc gatcctaacc ggcgacattc tggtggcacg
    10381 agcctcccag atggtggccg cgctggggcc cgacgcggtg ctggcacacg cccgcacctt
    10441 tgagcgccta tgcaccggcc agctgcatga gaccctgccg cgccctgagg gcgtggaccc
    10501 ggtagatcac tacattcagg tgctagctga taagaccggc tcgctaattg ccctgtgtgg
    10561 gctttatggc accatgctta ccggcgcggg cgccaaggct cagcggattg tggagcttta
    10621 cggtgaaaag atcggggtgg ctttccagct tgccgacgac gtcatcgata tttgctctga
    10681 ctcagaaacc actggtaaaa cccccggcac tgacctgctg gaaggggtag acaccatgcc
    10741 ggtgctgctg ctgcgtcagc gtttggcttc cggtgagctc gacagcgccg gccaggccat
    10801 tttgtcgctg ctttctaccg gtaacttgca gcgccagcag gtgcttagcg atgtggtgca
    10861 gcgcctacgc aaccacccgg ttactgccga gacccgcgct atggctgggg cttggtgtga
    10921 tgaggcggta gcagccctag ctgatttgga cgacgccgtc gtcgaagcta cccgcacccg
    10981 cctggaagct gagggcttaa gcgaggctga agtgacccag ggagttgaaa gcgcccgtag
    11041 ccgcgcccag ctggtacgca gaggcctgga ggacttcgcc cacctactgg tggatcgcgc
    11101 cgcctgaaac actttagtgt tttaacaatt agcacaacgg ctcactaaag ggccgcgttg
    11161 accacaaaac taccctcgcc agcggcgggg gtagttttct tggggnnnnn nnnnnnnnnn
    11221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11281 nnnnnnnnnn nnnnnnnnnn nnnnncgcca gcggcggggg tagttttctt ggggtagcct
    11341 tagaagcgct tgctgagggc tgccagtgtg ctaaccgtaa agctcgcccc tacttcctaa
    11401 tctccgttta ttcttgagga aaatcgtgac cgctctaaac gttgcagtga ttggtgctgg
    11461 cccggccggc atctacgcct cggacatcct gtctaagtca ggcttggacg ttaacattga
    11521 cctgttcgag cgcctgcctg caccctacgg gctggtacgt tacggcgtgg ctcccgacca
    11581 cccgcgtatc aagcagatca ttgtggcgct atacaagatt ttgcagcgcg gcgacattcg
    11641 cctgattggt aacgtggaag ttggccgcga cgtgagcgta gctgagctgc acgaacacta
    11701 tgacgccatt attttctcca ccggcgctga cactgacgcg cccctaaaca ttcccggcgc
    11761 tgacgcccct gaatgctatg gcggcgctga ctttgtttcc tggtacgacg gtcacccgga
    11821 ccacccgcgc acctggccgc tagaggctaa ggaagtagcc gtgctgggtg tgggtaacgt
    11881 gggcctagac atttcccgag tgctagctaa gcacgctgag gacctgatgg tcaccgaaat
    11941 ccctgagaac gtggccgaaa ttcttaaaac caacccctgc actgacgtgc acgtctttgg
    12001 ccgccgtggc ccggcccagg ttaagttcac ccccctggag ctgcgcgagc taggcaagca
    12061 gcgtgacgtg gatgtgctgg tggatgaggc tgactttgag tacgacgccg gcagtgaggc
    12121 tgcgctcaag tcctccaacc agcagcgtca ggtagttaag gcgcttgagg gctacgccat
    12181 gcaggagcct gaggagctaa ccgcctcgca ccgtattcac attcacctgt tccagtctcc
    12241 cgccgaggtg cttaccgacg acgctggtca cgtggtgggt ctgcgcactg agcgcacccg
    12301 tctaaccggt gacggcacgg tggagggcac cggcgtgttc accgactggc cggtacaggc
    12361 tgtttaccgc gccattggtt acgcctccag cccgattgag ggtatgcctt ttgactctaa
    12421 gcgccacgtg attcctaacg agggtggccg cgtattgggt gaggacggca agccgttgac
    12481 cggcatgtac gccaccggct ggattcgccg tggtccgatt ggtttgattg gctccaccaa
    12541 gtctgacgcc caggaaacca ttactaacct ggtggctgac gctaacgctg ggctgctaca
    12601 cgccaccacc gacgccgtgg ggcacgacgc catgattgcg ctgctctcta gccgtgacat
    12661 ccccttcacc acctgggagg gttgggagct gctagacgcc tacgagcgtc agctaggtga
    12721 ggactttggc gagctgccta acggcaagac ccgtgagcgt gtcaaggtgg ttaaccgcca
    12781 cgccatggcc gacatttcgc gcggcaagca ggctccgcag gacctaatcg gtcagcctga
    12841 caccgaccgc gtgcccgagc gtgtagccca ccgcctgccg gctcaggact aagctccagt
    12901 tggcgtaggc tcagcccacg ccaatctaga ggagctaaaa cgacgcataa cggcgttgtg
    12961 taggcgtggg cgctagccca gagcaatatt gaccaaacgt gcaggccgca gcttagctgc
    13021 ggcctgcacg cctgtttagc ctggtttaac gctttaagct ggtttatgca ccagcctggt
    13081 ttagcgcttt agcgttggtt taacgcgggc cctctagatc aggattagtt aattcaggtg
    13141 cgctaaaact cctgatttgg gccgcctcgc tggcaattgg gctggggcta gtgagcgtgt
    13201 tgccaaggtt ttctaggccc ttggcggtgc ttagcaggtt cttctcaatt gaattcacgg
    13261 tcttgttata ggtttgcacg ctgcggcgca ggctagcgcc caaatcatcc atatagcgag
    13321 ccacagtacc caggcgctta tacaaggtgg agccgatagc cagcagctga cgggcgtcgt
    13381 cgttaatggc gttttgcatc caggcgtcag caaccgtacg ggccaccgcc aacagcgaga
    13441 tgggggtggt tagcagcacc ccgttagcca gggcgtattc aagcaggctg gcatccacct
    13501 ccaaggcggc gctaagcacc gcctcagagg ggataaacat gatggtgaac tgggggccct
    13561 ggcctagctg ctcgggatag ttacggcgga tgagctcatt aatgtgtgaa cgcaccgcag
    13621 cggcgtgatc ggacaggtaa gagttggctg cgtcctgatc gcctttagca cccgcatcag
    13681 cgccgcgcag gaaggcatcc agaggggctt tagcgtcaat ggccagaaat tccccaccgg
    13741 gcagcaaaat cgtggcgtct gggcgcgcag agccgttagc gggggaaggg gccgcgttta
    13801 aagagccagc gcggttttgc ttacgcaaag tggacacgct tttttgcagc tcaaagtcga
    13861 tgtgctcact catcccgccc agctccagga cccggcgcag ctccatctca ccccacatgc
    13921 cgcgcgctga acgtgaacgc agcgccgatt ccagggaggc ggtggaggcc cgcagacgct
    13981 cctgggtagc gtctgaagcc cgcagacgct cagcaattat tgcgttctgt ttggagcgct
    14041 gcagctccat ttgctcaacc cgcaacgcca tatgctccag ctgctcgcgc accggctcaa
    14101 gggcggtgag taccgcgcca tcttggcggg cccgctgctg agcctccaaa gtgcgttgtt
    14161 gttcagtacg caactgctgc tccagggcct gtgcgcgggc actagccccg gcggcgtcgg
    14221 ccctaatgcg agccacctcc ccgccgttag ctgccaggcg ggctgcacgg gccgtggcca
    14281 gggcccaacc caacgcagta ccaagtgtta tacccaacaa caaaagagca attgcgttaa
    14341 cgatactcat aatttcctac tatctcaggt ctataccccg cagaaagccg ccatttttgc
    14401 gtgcttagcg acgtcgtcgt tactaactga agtaaagctt tatatgcgat gtgggctata
    14461 agtcacggaa aactaccaac atggtatgac caatgcatgt taccgttttg ttgtaaagct
    14521 ggatcgtaat cttggagtcg ttttggaata ccgcgcgggt actgtgcagg atctggatgt
    14581 tttggcccgc attggtgcgg atgccttctc agactacccc ctgtttcggc tgacagagcc
    14641 ggaactacga ccgggtgtaa ccttcgacca gtttcacttc gccttgcacc gaatgctggt
    14701 gaaaattttc cttaagcgcg aatctgtgct ggtggcttgt gaagacggta agccgcgtgg
    14761 ttatgcgcta ctgcaaaagc aagaaatgcc ttttttgcct tacctactta acggcggtgt
    14821 aggcctacta aagtacatcc cgctaaagcc gctactagaa ttccttaccc ttaccgacgc
    14881 ggctgaccag cacgtaaaac taaacaccca ctatgactgg ttcctggaag ttatcgcggt
    14941 gcaccccgaa caccagggac gcggcatcgg taccggcatg ttggatgtag gtatcgccaa
    15001 gtttgtaaag gccaccggcg gttctaacta cgcctttgtt accaacaccg ccaagaacgc
    15061 acgtttctat gaccacaacg gctgtcgtga gctggccgta agccacctgg actaccgagg
    15121 ccaggaaatc aacgtgtggg ctttcaagaa ggaactagac aagaagaagt ccaagcctgc
    15181 caaggacgca aaggccggcg ctaaggacgc caaggctgcc aatgaggcaa agcccgccaa
    15241 gaacaccgag gaaaccggca aataatcaaa gcgggccgca aacccgctaa actaggcgcg
    15301 tggctctaac tatcggaatt gtgggactgc ccaacgtagg caagtccacc ctgttcaatg
    15361 cgcttacccg cgcaaccgtc ctggcggcta actacccctt tgcgaccatc gaacctaacg
    15421 tgggtatcgt gccgcttccc gacgcgcgcc tggataaact ggcgcagatt ttcggtagtg
    15481 agcgcatttt gcccgctacg gtgtctttcg ttgacattgc tggaattgtg cgcggggcta
    15541 gcgaaggtga aggcctgggc aaccagttcc tggctaacat tcgtgaagct gacgcgatat
    15601 gcatggtcac ccgcgctttc gacgacccgg acgtggtgca cgtagacggc aaggttgaac
    15661 catcgtcaga catcgaaact atttccaccg agctggtgct ggctgacatt cagaccctgg
    15721 aaaaggccat cccgcgcctg gagaaggaag tgcgcggtaa gaagacagat cccgccgtgc
    15781 tgcaaaccgc taaggacgct ttgaaggtgc ttgaggaagg caccatgctt tcggccggcg
    15841 ctaaggcagc cgggctggat acagacattt tgcgtacctt ccagctgatg accactaagc
    15901 cgttcattta cgttttcaac atggacgacg ccggcatgca cgatgaggcc aagcaggctc
    15961 agctgcgtga actggtctct cctgccgagg ccatcttcct agacgcccag tttgaaagtg
    16021 aactggtgga gctagagccg gccgaggcct ccgaaatgct agccgacaac ggccaggccg
    16081 agtctggtct agaccagctg gctcgcgtgg gctttaagac cctgggcctg caaacctacc
    16141 tgaccgctgg ccccaaggag gcgcgcgcct ggactatcca ccagggctgg accgccccac
    16201 aggctgccgg cgtgatccac accgactttg agcgcggctt cattaaggct gagatcgtct
    16261 cctttgacga cttggtggag tacggctctg tggctgaggc ccgcgcccac ggcaaggtgc
    16321 gcatggaagg caaagactac gttatggccg acggcgacgt agtggagttc aggtttaatg
    16381 tctgagccta gctttaaata ggctctaaaa aggccgggtc gcgcattgag cgtggcccgg
    16441 ccttgctgtt gtcgttcgtc tggcatgcgg aaaatgaggt cctgatgacg atgcgtctta
    16501 acggcttgcg ttaataacgt gttccgacat attgttgagt catgatccag tcattcgggg
    16561 atcgtcagac tgagcgcttg tttgcgaggg aggctgtccc ttcccttgac tcgcgcatcg
    16621 ctcgcgttgc gctgcgcaag ttgcggcaga ttgacgccgc gtgtcgtctc gaggatcttc
    16681 gggttcctcc gggcaaccgg ctcgagcatc tgcgcggtga tagagcagga cagtacagta
    16741 tccgaatcaa tgatcagtgg cgtatctgct tcaggtgggg cgacgctggt ccagaagggg
    16801 ttgagatcgt tgactaccac taaaattgct ccgattcacc cgggtgaagt cctcatggag
    16861 gacttcatcg agggttttgg aattacgcag cataagcttg ccgtcgctat cgatgttccg
    16921 ccccgtcgta tcaatgagat cgtccatggg aagcgcggga tcacggcgga tactgccatg
    16981 cggctgtccc gctactttgg cacgaccccg gggttctgga tgaacctgca gatgcgctat
    17041 gagctcgatc gtgccgaaga tgtgctgggg gacaggttga gcggaatcgt tccgctcacg
    17101 atggtcgaag tcgcctaaaa ggtctcaatc tgacgaggca gtggccgggt cgcgcattga
    17161 gcgcggcccg gccttgttgt ggcgctggcc ttgggcttgc ggcgtcggcg gcccttaggc
    17221 ggcgtcggtg tctttagcgg gcttcgggga gccttggctc gaagcggtgc gtaaaacctt
    17281 agagctggtg gggcgctcta ggcgcaccaa gaggtcaatt tgcttaggtt catagcccag
    17341 cgagatgctc acatcctgct gaaggcggct gcgtagcgtg gacacagtcc agtcaatctc
    17401 gcactcttga gacacgctgg catcagcctg aatctgcagg tggcttaagg tgccgctaac
    17461 ccacactgtg cagcgctcca ccccgggcac gccctgcgcc cgctcagata gggcctgcga
    17521 caaaacctca gggtccaagg tagtgagtaa aagcccctca gagtcactca ggcgcatcgg
    17581 tgaggccgct acccggcgcg gcacctgcat gagaagcagc gccagaccac caatgatggc
    17641 aagcactgag gccagcgcaa gcacgggtaa aagccagttt gcttgactgg cgacggcgcc
    17701 cacccgcccc tgcttgctag ccaggtaggg ggcggcgtcg ggccaaaaac gagctaaacc
    17761 caggccggaa gccagcagcc aagcggaggc agccagcaaa acaaagccac agatagccag
    17821 gacgcaccgg tttagcgggg tggaaactga acgcataatc gtgtctcctt agctcgcgtg
    17881 cttgacgcgc acgcgactgc ctttaatacc caccggggcg agcatttgta gggcctggtc
    17941 agtctgcttt tgggcggcct gctgcacggg ctctagctca tctaggacgc tgtggacgac
    18001 gacgttaacc cgcgagcggc gggcagtggc cgaaacggag ttagcaccgc ccagctgctc
    18061 aacctgtagc ctcaccagtt tggccaggtc acggcgccta actgcggtct ggccaggaat
    18121 gtcatcaggg agaatttcga cgcgctcagg ccgcccgggc catagcgccg caataatcat
    18181 gattaggcca caggccgcca caaccccggc ggcaataagc gccgcagtgg agctaagcga
    18241 agtggatttg atggcttcaa gtgcgtgtag ggcgtggcgc ggccagtagc cggtgatgag
    18301 ccgctggccg gttagccaag cccccaggct tccgccggca agcagcaaca gggctagaac
    18361 cacgctggag ccgctgcgtg aggggcggcg aatgagtttt ggaacttttc tcatttcagg
    18421 ttcttcctgc ctggaccgtc ggggttaagc caggagatct caatattgat cttgccgacg
    18481 ctcagcccgg tcaggtgctc cacccggctg cgtacatgtg cgcgcacggc ctcgattgtg
    18541 tctgccagtg gtgtgggaaa aaccaggcct aggttcatgt gtaagacggc cacctgcccg
    18601 tagagctcac attgggcgtc ggggcgggag gaaaagttgc ggcgggcgcc gatgcctaaa
    18661 accccgccgg cgttggagcc aacattgccg gtttcatagg cggcttcggc ggcaattttg
    18721 gccacgactt tagccggaat ggtggtgctg ccgcgctggg cggtgcccgc gtcggtgtca
    18781 gcggcttggg cggtgccgcg ctgcccggcc tgcccggttg tgggctggag gcctgaggac
    18841 tgggtggctg taggtgaggc gagggacgcc atcgtcactt ccttagccgc tcaaggaagc
    18901 tgcggacatc gacccggccc tccaggtaca ggcccacccc caagccgacc aggccacaca
    18961 gtgacaccag cacaaagtca gcgaaggagc caaaagccag aacggttcca aggaacaggc
    19021 ctactaggag ggccaggtgc gttgtcttca tgagatctcc tcagatcaag gcgtaaatta
    19081 cttgaggttg ttggtctcag actcgtcgcc gggcaggtgc acgtcggtga cgtggatgtt
    19141 gacctcaact acttccaggc cggtgctggt ctcgatctgc tcaatgatgt tgttacggat
    19201 cgcctcggtg acctcaatga tgggggcgcc gtagtcaacc accacggtga cctcaataga
    19261 ggtttgggtt tcgcccttct gtacgttaat gccgccggtg acgttggtct gggcggtggg
    19321 gatgcgctcg gtcatggcgg tgaaggcgcg gcgcatggcg ttacccatgc tgtagacccc
    19381 gggcacctcg cgcgtggcca tgccggcgat cttggcgatg acattctcgt caatggtggt
    19441 tacgccgtgg gaggtgtgta aaggagtgtt gggggtgctg cccgcttcag tgttttcgtt
    19501 ctgctcaggc tgcttgctgg tgtcgctcat gggaggctct ttctttgatc tgagtaggtg
    19561 gccgacggcg cacagagttt ggccgtcagg gttggcgttg attgccgtca tgattgccgc
    19621 gataaacgca ctaaaaggtg cggttgtcta agaatcctta ccgcctcagt ctatagggct
    19681 ttcgtcttaa aaaggtgaag tggggcagtt ttaaaggagc tttcttttct gactcgatat
    19741 tggctcgcct atattggatg tgttcacggc ttgcataggg aggaaaagtt catggatcct
    19801 cgtttttcgc gcgcatatgg cgcattggct gggttagcgc tgggcgatgc gctgggtatg
    19861 ccaacgcaag cgatgtctcc acagcagatt caaacggttt acggccatgt cacgggcctg
    19921 gtggatgggg ataaaagcca accctatgcg ccgggtatgg cggccgggtc ggtcactgac
    19981 gacaccgagc aagcattatt gatcgcttcc ctgctgctta aaggccacgg ctctgggctg
    20041 aacttagatg cgggcgagtt ctcccacgcc ctgctggctt gggaggattc catgattgag
    20101 cgtggctcgc tggacctact ggggccctcc acaaaggccg cacttgagcg tgtacgcgca
    20161 ggtgaagacc cactgcgtgt gggcggtgag ggcaccacta atggggcggc aatgcgggtg
    20221 acaccgatcg ggattgcggc gtcgacgtcg gaccggcagc ttttcgccga caccgtatgg
    20281 tcctcatgcc aggtcacgca cgccacccgt cagggctttc agtcagcggc gctagtggca
    20341 gccgccgtgt cactcgggat cgacgccggc gcggcggatg tgacagacct gctgtggaag
    20401 gctgtggctt ttgtgcgctc actacctgag cgcggcgcct ggagcccaga gccggatgtt
    20461 gtggcagcca cgcaccgggc attaaaactg gctgcccagc cgtcgtcgtc cctagagtgg
    20521 ctggccgagc agatcggcac ggctgtggcc tcagcgcagg caatccccat ggctttcgcg
    20581 ctgctggcac gtgatccctc cccatgcgcc ctgctgcagg ccgccaattt ggggggtgac
    20641 actgacacaa ttggtgcgat agcaggcgca attttgggtg caagcttggg tgttgaggtt
    20701 tttgacgctt acggtctggc ccaggtggag caggtttcgc agcttgatct gcctagcgtc
    20761 gctacagatt tgctggctct gcgtgatagg gagggcggcg gctctacccc cgcagcagct
    20821 acgacgtcgc ccaacccaga aaaacccgtg ctcaccccag ccgcgtcccc acaaaaaggc
    20881 gccccggcgg gccgcgtggt gctgatgggc cagatccttg tagacctggc tgtgcgtggc
    20941 gaggcactac cggcccctgg cggcgacgta tgggccagcg atgaaggaat gcacgtgggt
    21001 gggggcttta acgcgctggt ggccgcgcgg cgtatgggag cccaggccgt ctcgctcagc
    21061 ccgattggcc acggtcccta ctctttactc atccagcagg ccctgca
//
