LOCUS       NZ_KE951478            21107 bp    DNA     linear   CON 11-DEC-2024
DEFINITION  Actinomyces graevenitzii F0530 Scaffold126, whole genome shotgun
            sequence.
ACCESSION   NZ_KE951478
VERSION     NZ_KE951478.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Actinomyces graevenitzii F0530
  ORGANISM  Actinomyces graevenitzii F0530
            Bacteria; Bacillati; Actinomycetota; Actinomycetes; Actinomycetales;
            Actinomycetaceae; Actinomyces.
REFERENCE   1  (bases 1 to 64782)
  AUTHORS   Weinstock,G., Sodergren,E., Wylie,T., Fulton,L., Fulton,R.,
            Fronick,C., O'Laughlin,M., Godfrey,J., Miner,T., Herter,B.,
            Appelbaum,E., Cordes,M., Lek,S., Wollam,A., Pepin,K.H.,
            Palsikar,V.B., Mitreva,M. and Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2013) The Genome Institute, Washington University
            School of Medicine, 4444 Forest Park, St. Louis, MO 63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: High-Quality Draft
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: Velvet v. 1.1.06
            Genome Coverage                   :: 191x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000466185.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 10:46:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,803
            CDSs (total)                      :: 1,747
            Genes (coding)                    :: 1,701
            CDSs (with protein)               :: 1,701
            Genes (RNA)                       :: 56
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 46
            CDSs (without protein)            :: 46
            Pseudo Genes (ambiguous residues) :: 0 of 46
            Pseudo Genes (frameshifted)       :: 5 of 46
            Pseudo Genes (incomplete)         :: 43 of 46
            Pseudo Genes (internal stop)      :: 4 of 46
            Pseudo Genes (multiple problems)  :: 5 of 46
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:20:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 36701
            Orig. end                         :: 57808
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KE951478.1.
            Bacteria provided by Jacques Izard, and Floyd E. Dewhirst, (The
            Forsyth Institute, Department of Microbiology, 245 First St,
            Cambridge, Massachusetts, 02142).  Funded by NIDCR DE016937 'A
            Foundation for the Oral Microbiome and Metagenome'.
            Source DNA provided by Alice Kirega, Anne C. Tanner, Floyd E.
            Dewhirst, and Jacques Izard (The Forsyth Institute, Department of
            Microbiology, 245 First St, Cambridge, Massachusetts, 02142).
            Funded by NIDCR DE016937, 'A Foundation for the Oral Microbiome and
            Metagenome'.
            The bacteria was isolated from a human subject. The phylogenetic
            relative position is available at www.homd.org.
            Coding sequences were predicted using GeneMark and Glimmer3.
            Intergenic regions not spanned by GeneMark and Glimmer3 were
            blasted against NCBI's non-redundant (NR) database and predictions
            generated based on protein alignments. tRNA genes were determined
            using tRNAscan-SE and non-coding RNA genes by RNAmmer and Rfam. The
            final gene set is processed through several programs such as Kegg,
            psortB and Interproscan to determine possible function. Gene
            product names are determined by BER. Gene names are generated at
            the contig level and may not necessarily reflect any known order or
            orientation between contigs.
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            This work was funded by the National Human Genome Research
            Institute (NHGRI)/National Institutes of Health (NIH) grant
            5U54HG00496804 for characterization of this genome.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21107
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21107
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21107
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11107](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11107
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(152..2167)
                     /locus_tag="HMPREF1978_RS00180"
                     /old_locus_tag="HMPREF1978_00818"
     CDS             complement(152..2167)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005985380.1"
                     /locus_tag="HMPREF1978_RS00180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00818"
                     /product="M3 family metallopeptidase"
                     /protein_id="WP_021603012.1"
                     /transl_table=11
                     /translation="MSELFSATIAAMEADLDPANPLAKPWSLELGLPDFSVLKHEDFEP
                     AIRAGMRQQRAQWEAIATNPQPPTVDNTVVACELSGALLERALIALGALTSATYCPDLD
                     DLEERLAPELSEHSDAYSLDARMYRRYKQLAESDQEFDEETKRVITLAVEEFERDGVAL
                     EGADLAKLRELNAAITKLSARFHTLVTDEIHASGVANFTLTPQLATLESHDERVALLNK
                     AKSRNFGGERDTRQIVEQLAKLRAQRAQLLGFEHHAASVAAESAAKTTQAVNAMLSRLA
                     GPAMANARRDGQRLAQRMAQAEPGVEFTTADWLRYEEAERKELFGVDDEILAPYLELNN
                     VIDGVFFAANRLYGITFHEREDLAAHMYDPDLRVWEVREADGSVLALFVGDYYARKGKS
                     GGAWMNTFNEPGALTDTKPIIINCLNITKPASGPTLLSWDNVITCFHEFGHALHGMFGA
                     TYYPSVNGTNVARDVVEFPSQVNENWALHPQVLARYARHHVTGEPMPANLLEQLRAQGS
                     FGQGYMTSEYLGAALLDQAWHQLAPEQVPTEAEQVEEFEHQALAQAGIDDSLVLPRYRT
                     AYFSHAFGGGYDAAYYAYIWSEVMDADAVAWFRTAGLGAIGTEADNDGGLNRQAGQRFR
                     DEFLSRGDSREAALSYQRFAGRKPSLEHLLKRRGLD"
     gene            complement(2293..2874)
                     /locus_tag="HMPREF1978_RS00185"
                     /old_locus_tag="HMPREF1978_00819"
     CDS             complement(2293..2874)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HMPREF1978_RS00185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HMPREF1978_00819"
                     /product="hypothetical protein"
                     /protein_id="WP_034477583.1"
                     /transl_table=11
                     /translation="MGNTSTTGASYHLPDNVTYDDAVDPDFSHAVGFGPAQDEQVPTWL
                     ALAKYTAWFTFSQVVTLIVYMVVHSYLYTPVGQIRIPLGLLQFLDSFTGVGSLGPFMLL
                     AVFFCAGPKIRQVRAFISYPFVVAMALLTTWVMLFFEDATRTFFHGALMLDIAYWEVSR
                     YALPCAGMGALLGLGLRHLFHWGRDRWLNR"
     gene            2979..4175
                     /locus_tag="HMPREF1978_RS00190"
                     /old_locus_tag="HMPREF1978_00820"
     CDS             2979..4175
                     /GO_function="GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036297 - interstrand cross-link repair
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017984.5"
                     /locus_tag="HMPREF1978_RS00190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00820"
                     /product="DNA glycosylase AlkZ-like family protein"
                     /protein_id="WP_034477586.1"
                     /transl_table=11
                     /translation="MSACPTLPVMVSLARIVSQGLVPATSATSVVQAVNNLLAVQGQQV
                     SALPHALLERTPGAKFSDVTTAFNQLELVRSRPMRGTVHITSAADYHWLRLTLNQRSNY
                     SLRNQSILGGISETDLETAWQLVKTHAPTQGIRRKDMFALWVQAGLAVKAQNATSLKAP
                     PTKQARVNRWCNLMMWQLDRQGLVVEGPMGTNEHRFIDATCLPAATSAASGFKFDPADL
                     RAARMEVARRYAYGHGPVSVADLARWAALPVTQARQALEDAVSNSELIVRVKIEENTFT
                     PAAPPKVVKEYNQLLYMRADLPDLLADNLSQARRLIYLPAFDELHVGYRNRTCLTDGAG
                     EKLICPTANGLFRPLIVNNGRLIAVRPASSGVIWLDKPTPYMDKRVNKLVDNRLESLQ"
     gene            4211..5089
                     /locus_tag="HMPREF1978_RS00195"
                     /old_locus_tag="HMPREF1978_00821"
     CDS             4211..5089
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017195183.1"
                     /locus_tag="HMPREF1978_RS00195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00821"
                     /product="N-acyl homoserine lactonase family protein"
                     /protein_id="WP_021603015.1"
                     /transl_table=11
                     /translation="MSALTIFHTGSVIVDEALLYRRPSDHPLAWTHLLRDDSRLVEVPV
                     SCYLLEGRHGRMLIDTGWHPDNRTKLGQIANLRQQYLAKRAVLPQGQAIDEQLAQMGIS
                     PKDLDLVMLSHLHCDHADGLRLVKDAPGIMVSKAEWCAAKRDHLRYLPHQWKHVAINTY
                     PWNTKIGPWDAGFDVYGDGSVVTVALPGHSYGLTATIIRSSNISSSDPARWVPNASGDG
                     VHDGREFILLTSDAGYGRPSLEEDLRPGMVIKAGWARRSLDWIRQVSKDPRCLRVIASH
                     DPEIIPETIQL"
     gene            complement(5179..7314)
                     /locus_tag="HMPREF1978_RS00200"
                     /old_locus_tag="HMPREF1978_00822"
     CDS             complement(5179..7314)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005985389.1"
                     /locus_tag="HMPREF1978_RS00200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00822"
                     /product="type IIA DNA topoisomerase subunit B"
                     /protein_id="WP_034477588.1"
                     /transl_table=11
                     /translation="MSEAPAYSARHLSVLEGLEAVRKRPGMYIGSTDQRGLMHCVWEIV
                     DNAVDEALEGYAKNIDVFVHTDGSIEVRDDGRGVPVDTEPSTGLSGVELVYTKLHAGGK
                     FGGGLYGAAGGLHGVGASVVNALSARMDVQVDRGGKTYAMSFRRGEPGIFDDSSGMSPN
                     SPFTAFDEASELRVVGKVKRGVSGTRVRYWADRQIFPSPNDYDGAALASRLRQTSFLVP
                     GLSLRLIDERSVVVDNETDAADARKPAGPQTYLALGGTADFVDYLAKDGSVTDTFRLTG
                     QGTYNETVQQLDERGHLRPVEVERTCQVDVALRWGIGYDTCERSFVNIIATPLGGTHLA
                     GFEQAVVKVMRKQISVNSRALKLNSRDGKIEKDDVLAGLTAVVTVRVPEPQFEGQTKEV
                     LGTAPVRAIVAAVVEKELTALLNSPKRDLKAQARALQEKIVGEMRARVSARMHKEITRR
                     KTALETSTLPAKLADCRSDDVATSELFIVEGDSALGTAKNARNSENQALLPIRGKILNV
                     QKASAADMLHNAECAAIIQVVGAGSGRTFDISSARYGKVILMTDADVDGAHIRTLLLTL
                     FFRYMRPMIEAGRVYAAVPPLHRIEVSAKGRKKKEIIYTYSDEELVSTLGKLEKQGRTF
                     KEPQRYKGLGEMDAHQLAETTMEPQHRMLRRITLADEAAVELAESTFELLMGSSVAPRR
                     EFIIDSADEVDRERIDA"
     gene            7445..7660
                     /locus_tag="HMPREF1978_RS00205"
                     /old_locus_tag="HMPREF1978_00823"
     CDS             7445..7660
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005985391.1"
                     /locus_tag="HMPREF1978_RS00205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00823"
                     /product="hypothetical protein"
                     /protein_id="WP_005985391.1"
                     /transl_table=11
                     /translation="MNVSSVLNQSASQAVEPLNVADRCDLCGARAYMRAVLMNGPLLFC
                     AHHGKANLEALRAQALRIDDFTDELD"
     gene            complement(7764..9374)
                     /locus_tag="HMPREF1978_RS09780"
                     /old_locus_tag="HMPREF1978_00824"
     CDS             complement(7764..9374)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008733797.1"
                     /locus_tag="HMPREF1978_RS09780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00824"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_021603017.1"
                     /transl_table=11
                     /translation="MSVAPNKASRKPVDAELEFDPEDEEYDESLEEDLVDEDFEEDSEQ
                     DSDEDADEESDDYDAEPAPAPAPEKRDYYLDVNLENNGDGSKKSPFNTPAAFKDIRLAP
                     GSTLFVRSHTVVKDLEIVGDGTLEEPITLAPYGHGPVPRFIYKGSAPMVARDFLTQNGL
                     VFRGWVIKGIKMQPSIAALTGDLERVRQEEAEKANAKKKGKRSKKEEKKGYTVNDSDEG
                     DEPAQKVVTAGATADPVKDYLKQIGKVALLNAVQEVELAKRIEAGLYAEHILADKSAEL
                     TSKYRRELYWITQDGQRAKNHLLEANLRLVVSLAKRYTGRGMLFLDLIQEGNLGLIRAV
                     EKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLARVQRQMLQDLG
                     REPTPAELAVELDMTEEKVIEVQKYGREPISLHTPLGEDGDSEFGDLIEDSEAVVPADA
                     VSFTLLQEQLHAVLDTLSEREAGVVSMRFGLTDGQPKTLDEIGKVYGVTRERIRQIESK
                     TMSKLRHPSRSQVLRDYLD"
     gene            complement(9494..9886)
                     /locus_tag="HMPREF1978_RS08755"
                     /old_locus_tag="HMPREF1978_00825"
     CDS             complement(9494..9886)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012791.5"
                     /locus_tag="HMPREF1978_RS08755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00825"
                     /product="universal stress protein"
                     /protein_id="WP_021603018.1"
                     /transl_table=11
                     /translation="MAVIMSYHGTLESRAALVEAVNLAKRLDEKLLCVYAQKHRGDDLA
                     VDSQVMEVLHDALGQEDLDYAVQPCPRGKDVSEFVLEAARENHASYVVIGLAHCSRYGG
                     MNIGPNAQRLLLEAPCPVVTYTTRLD"
     misc_feature    9918..9938
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     gene            10001..11107
                     /locus_tag="HMPREF1978_RS00220"
                     /old_locus_tag="HMPREF1978_00826"
     CDS             10001..11107
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004565049.1"
                     /locus_tag="HMPREF1978_RS00220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00826"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_034477590.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.3e-39, bitscore:
                     125.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLPAHLASLRPHFDAQVCAHLGAYADSWRNTQALDEVFTILSS
                     ALAGGKRMRAILGAIGYAYASEFGAYKLALTSPQAAALGAALEFYQASALVHDDVIDHA
                     LTRRGQVATHVAFSKLHGDNGWRGNDSDFGGAAAILAGDALLAWGGDLVTQASEVTGNY
                     GAVNAFNHMCAEVALGQYLDVRNENLPLNGSDGEQMVSQSLAVIKHKSARYSVACPLII
                     GALLAGATPDSPAVKALETYGENVGAAFQLRDDELGVFGSSKVTGKPVGDDIREGKRTV
                     LVGLTWQLAGANGRALLSDVVGNTNASEMQIAAVADLMKDCGAYQKHEQLINDYLTRGL
                     ACLSHDALGASIIADLQVLAQVLTIRQA"
     gene            11170..12612
                     /locus_tag="HMPREF1978_RS00225"
                     /old_locus_tag="HMPREF1978_00827"
     CDS             11170..12612
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.5"
                     /locus_tag="HMPREF1978_RS00225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00827"
                     /product="protein kinase domain-containing protein"
                     /protein_id="WP_051256881.1"
                     /sec_met_domain="Pkinase (E-value: 4.4e-46, bitscore:
                     149.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDSVLGQVLDERYEVRARLAQGGMAVVYRGYDHRLGREVAIKV
                     MHSHLADNEAFVSRFKREAHSAAQLSDAGIVAVYDQGKTPSGRPYLVMELIDGITMRKF
                     IATRGYTLGRAIELTKQLLSSLETAHQVGIIHRDIKPENVLLPTNGKTAKVADFGLARA
                     ADAITATATGTVMGTVAYMSPELVRTGKAGTSADIFAVGVTFYELLTGTQPFTADTPVQ
                     VALLNVNEPIPAPSKLVPWLPPQIDEIVSALTNHDLNIRPANATKALELVERLVDTIPA
                     NVLKHDLDSEESHTLVDPMPVSSQHVAGVNVGLQSGAPVASRSAYSAASAPSNFSATSG
                     NSGQYSTPSYYSTPTYQPQMLAMADTGWQQSYSDDDDDEGLRRRGLLVGIPTALALAGL
                     AGIGAYILASPDKPSQVSIPDVTGKTQDDAVTALDDVGLKAAGISASSSTVPKGQVISQ
                     QPTAGTTAKTGDTVTLTISSGS"
     gene            complement(12715..14034)
                     /locus_tag="HMPREF1978_RS00230"
                     /old_locus_tag="HMPREF1978_00828"
     CDS             complement(12715..14034)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005985401.1"
                     /locus_tag="HMPREF1978_RS00230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00828"
                     /product="class II 3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_231385517.1"
                     /transl_table=11
                     /translation="MRNFDWRSCPAAQQPSYPDPQQLADVVNDLRRRPPLVFAGEADSL
                     RADMERAGQGKAFVLMGGDCAESFEKGDATTIRLKVQTILQMAIVLTYGASMPVVKIGR
                     MAGQYAKPRSADTETRNGVTLPVYRGDCVNGHEFTKSARVPDPKRMLDAYLRSGTTLNL
                     IRAFTMGGYASLSEVHSWNRGFTENPAYARFATMAGELDRSMRFMKAAGVDFGALTQVD
                     FYSAHEALLLDYEDAMTREDSRTGDPYDTSAHMLWIGERTRDIDGAHVALLSGVRNPIG
                     VKIGPDASPDELYALMDRLNPSGEGGRISFITRMGADLIEERLPALAQAVKADGRPVTW
                     ICDPMHGNTITSENGYKTRRFADILAETRSFFQVHRAVGTVPGGIHVELTGDDVTEVLG
                     GGEHIAEADLEQRYETLVDPRLNHQQSLEIAFEVAEMLRS"
     misc_feature    14006..14017
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     gene            complement(14105..15334)
                     /locus_tag="HMPREF1978_RS00235"
                     /old_locus_tag="HMPREF1978_00829"
     CDS             complement(14105..15334)
                     /EC_number="2.7.1.90"
                     /GO_process="GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004565052.1"
                     /locus_tag="HMPREF1978_RS00235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00829"
                     /product="pyrophosphate--fructose-6-phosphate
                     1-phosphotransferase"
                     /protein_id="WP_021603022.1"
                     /transl_table=11
                     /translation="MSVRRVALLTAGGFAPCLSAAVGDLIERYTEVAPEVEIIAYQYGY
                     HGLLTGNYIVIDEEARKNAGLLRNFGGSPIGNSRVKLTNAKNLVERGLVAEGVDPLAFA
                     AEQLRKDGVDVLHTIGGDDTNTTAADLAAYLHEHNYELTVVGLPKTIDNDVVPIRQSLG
                     AWTAADEGANFAFNVIGEHRSNPRMLIVHECMGRNCGYLTAETALRYRQLLDTKQWAPS
                     LGLTRERWDVHAVYLPEVKLDIAAEAERLKAIMDEQGNVNIFLSEGAGVPEIIAELEAA
                     GEEVQRDPFGHVKLDTINPGQWFAKKFAKLIGAEKVMVQKSGYYSRAAAAHQEDLDLIK
                     SMCDLAVDCALRGEPGVIGQDEENGDVLTAIAFPRIAGGKPFNIDQDWFKGLMEGIGQH
                     VEASDAPVEH"
     gene            complement(15430..16284)
                     /locus_tag="HMPREF1978_RS00240"
                     /old_locus_tag="HMPREF1978_00830"
     CDS             complement(15430..16284)
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005985404.1"
                     /locus_tag="HMPREF1978_RS00240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00830"
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_021603023.1"
                     /transl_table=11
                     /translation="MGYRAIKATAGPAIHMMYQPWIRGEEHIPVEGPAILASNHLAVID
                     SFFLPLMIEREVAFIGKSDYFTGKGLKGWGVKKFMTSVGTIPVDRRGGKYSMAALQAGI
                     DRLNSGELFGIYPEGTRSPDGRLYRGKTGVARVALATGAPVLPVAMIGTNIAQPIGQVV
                     PRLHRIGVVIGQPLDFSRYQGLENDRFVLRSITDEIMYSLMALSGQEYVDLYAADVKKM
                     MDADKLSAAEVVEKMLAAQAEANPLAMPVQAPGGRQAPLTSVPQPPAEVEEPAAQSEED
                     SAK"
     gene            16375..18054
                     /locus_tag="HMPREF1978_RS00245"
                     /old_locus_tag="HMPREF1978_00831"
     CDS             16375..18054
                     /GO_function="GO:0003724 - RNA helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000027 - ribosomal large subunit assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005985406.1"
                     /locus_tag="HMPREF1978_RS00245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00831"
                     /product="DEDD exonuclease domain-containing protein"
                     /protein_id="WP_330932964.1"
                     /transl_table=11
                     /translation="MSTVAKAPNPDPNYPHQASLLQMGTPLEQVTFVVVDLETTGAQPG
                     PDAITEFGAVRVRGGEILDEFGSLANPGTAVPAYITMLTGITTSMVASAPPLEEVLGDF
                     MSWARLDEPDTVIVAHNARFDVSHLRSAAGAFGFDWPSVRVLDTLKLTRKAWSRNDVAN
                     HKLSTLARFVGAQTTPTHRALDDARATVDVLYAALEKVALQGLTHMEDLTSACDPVPAS
                     RRAKAAMAADLPQAPGVYRFYSPGNQVLYVGSATNLRQRVRSYFTASESRGHIATMLDV
                     ADRVEYDRYPTLIEARVQELRQISFYDPPANRRSRKHATKAWLKLTSGPRPRLSIVSYV
                     DYEQLSKGGVIGPYSSRRSANAARVAIEEVFALDRVGDKGISDTVSDEDYPALADLAYQ
                     ALSDNATLVVDPLMQRIQTLAQAQRYEDAGVITKRLQAYVRGLERVQRLRPLFTCPYLV
                     SARRRSLGGWEFVAISHGQLLGSAVSPSGVYPLDVLAEFEAFLSPITPPERIMGTLMLE
                     EANLLADWALDEGARLVSLDPQANLSWPIDSPARHAKLLAHA"
     gene            complement(18056..18472)
                     /locus_tag="HMPREF1978_RS00250"
                     /old_locus_tag="HMPREF1978_00832"
     CDS             complement(18056..18472)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005985408.1"
                     /locus_tag="HMPREF1978_RS00250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00832"
                     /product="hypothetical protein"
                     /protein_id="WP_021603025.1"
                     /transl_table=11
                     /translation="MTSAPESDSVELLVFSDDSDTRKQVIEAVGRRPDKGLPRVTWFEC
                     ATAEAVRLALKENPTRFAALVFDSEVKKFGGMGLAHELLTEMDSRPAVVMLTARPQDGW
                     LSAWAHADAVVSRPLDPVTVAQAVAQAMRKQLAK"
     gene            18632..19255
                     /locus_tag="HMPREF1978_RS00255"
                     /old_locus_tag="HMPREF1978_00833"
     CDS             18632..19255
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005985409.1"
                     /locus_tag="HMPREF1978_RS00255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00833"
                     /product="superoxide dismutase"
                     /protein_id="WP_021603026.1"
                     /transl_table=11
                     /translation="MAIYTLPELPYDYAALEPHISGRIMELHHDKHHAAYVAGANSALE
                     ALAAAREEGNLGAINLWEKNLAFNLGGHTNHTIFWNNLSPNGGGEPEGELAEAIKDSFG
                     SFEKFRAHFTATALGIQGSGWAVLAYDSISGKLVIFQLFDQQANVPVGTVPLFMVDMWE
                     HAFYLDYLNVKADYVKAIWNIANWSDVAKRLDNAVANAKQLILG"
     gene            complement(19459..20460)
                     /locus_tag="HMPREF1978_RS00260"
                     /old_locus_tag="HMPREF1978_00834"
     CDS             complement(19459..20460)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012478.5"
                     /locus_tag="HMPREF1978_RS00260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00834"
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="WP_034477593.1"
                     /transl_table=11
                     /translation="MRRSLTAAAALLLAASLGLAGCSGDGKKSAKAAATPASAATKQEK
                     VDCSKLKIDTDSKALPTIGQPSSNKAPAITWVKGAKAPTNLTVKTIKAGSGAAVAADSN
                     VAANYSGWKWDSATTFDSSFERGSATRFGLNGVIDGWRCGLLGHKVGDVLEISIPGKLA
                     YGDKPANPQAPAGTLVFYVELTDALTTAQISAASKDATLVEGATEELEKNGITVTGKLG
                     QAPSITIKAGISAPTSAKLITLASGNGEKLTDTDTALGYMAMATWDGNKRSSWTESSPQ
                     PVQMSVSQIKQLVDLSGIPVGSRVVIILPPQASSQGGQTTPASVYVFDIAAK"
     misc_feature    complement(20451..20465)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.79"
                     /tool="antismash"
     gene            complement(20541..20906)
                     /locus_tag="HMPREF1978_RS00265"
                     /old_locus_tag="HMPREF1978_00835"
     CDS             complement(20541..20906)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005985413.1"
                     /locus_tag="HMPREF1978_RS00265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF1978_00835"
                     /product="iron-sulfur cluster assembly accessory protein"
                     /protein_id="WP_005985413.1"
                     /transl_table=11
                     /translation="MSQTTNEVATHEVMLTDVAAAKVASLLEQEGRDDLRLRVGVQPGG
                     CSGLVYQLYFDERVLDGDAIRAFGEEGKQVEVIVDRMSIPYLNGATIDFADTIEKQGFT
                     IDNPNAVGSCACGESFH"
ORIGIN
        1 gcctttttgc agctagcgcc gccgatgaag tttcaccggc ggcgctagca acttgatact
       61 gcctaagagc agcaattaaa cggtcaagtg aggctccagg gtcagtctcc atgtcctaac
      121 catagcctca tgtatgtgcc ttggcacatg tttagtccaa accacggcgc ttaagtaggt
      181 gctccaagct gggcttacgt cccgcaaagc gctggtagct aagggccgcc tcgcggctat
      241 cgccacggct gaggaactca tcgcggaagc gctgaccggc ctgacggtta agtccgccgt
      301 cgttgtcagc ctcagtgcca atcgcaccca ggccagcagt gcggaaccag gccaccgcgt
      361 cggcgtccat aacttcactc caaatgtagg cgtagtaagc ggcgtcgtag cccccaccaa
      421 aggcgtggga gaagtaggcg gtgcggtaac gcggcagcac tagggagtcg tcaataccag
      481 cctgggctag tgcctggtgc tcaaactcct ccacctgctc agcctcggtg ggtacctgct
      541 cgggggcaag ctggtgccac gcctggtcta gtagggctgc gcccaggtat tcgctggtca
      601 tgtagccctg gccgaaacta ccctgggcac gcagctgctc tagcaggttg gcgggcatgg
      661 gctcgccggt tacgtggtgg cgggcgtagc gggccagtac ctgggggtgc agcgcccagt
      721 tttcgttaac ctgagagggg aactccacca cgtcacgggc tacgttagtg ccgttaactg
      781 acgggtagta ggtagcccca aacatgccgt gtagggcgtg gccaaactcg tggaagcaag
      841 taattacgtt gtcccagcta agcaaggtgg gtccagaagc aggcttggtg atgttgaggc
      901 agttaatgat gatcggcttg gtgtcagtca aggcgccggg ctcattaaaa gtattcatcc
      961 aggcgccacc ggacttaccc ttgcgggcat agtagtcacc cacaaatagc gccagcacac
     1021 tgccatcagc ttcgcgcact tcccatacac gcaggtcggg atcatacata tgagcggcca
     1081 ggtcttcgcg ctcgtggaaa gtgatgccgt agagacggtt ggcggcaaag aaaacaccgt
     1141 caatgacgtt atttagctcc aggtaggggg ccaaaatctc gtcatccaca ccgaacagtt
     1201 ctttacgttc ggcttcctca tagcgcagcc agtctgcagt ggtgaactcg acgccgggct
     1261 cagcctgagc catgcgctgg gctagacgct gtccatcacg gcgggcgttg gccatagccg
     1321 gaccggccag gcgtgaaagc atggcgttta cggcctgcgt ggttttagct gcagattctg
     1381 cggccacact agcggcgtgg tgttcaaaac ccaacagctg ggcacgctgg gcgcgtagct
     1441 tagctagctg ctcaacgatc tgacgggtgt cacgctcacc cccaaagtta cggctcttag
     1501 ccttgttaag tagggctaca cgctcgtcgt ggctttctag cgtggccagc tgcggggtga
     1561 gggtaaagtt agctaccccg ctggcgtgga tttcgtcagt aaccagggtg tggaaacgcg
     1621 ccgaaagctt agtgatggcg gcgtttagct cacgtagctt ggccaggtct gcgccttcta
     1681 aggccacgcc gtcgcgctca aattcttcta cggccaaggt gataacgcgc ttggtttcct
     1741 cgtcaaattc ctggtctgat tcggccagct gcttgtagcg gcgatacatg cgcgcatcta
     1801 gcgaataggc gtcagaatgc tcgctcagtt cgggagctag gcgctcttct aagtcatcta
     1861 gatccgggca gtaggtggct gaggttagtg cacctagggc gattagggcg cgttcaagta
     1921 gggcgccgct aagctcacag gccaccacgg tgttgtcaac ggtgggcggc tgcgggttgg
     1981 tggcgatagc ttcccactgg gcgcgctgct ggcgcatacc ggcgcggata gcgggttcaa
     2041 agtcttcatg ctttagcacg ctaaagtcag gtaggcctag ttccaggctc cagggcttag
     2101 ctagcgggtt agccgggtcg agatcggcct ccatggctgc gatagtggct gagaaaagtt
     2161 cactcatgta cctatgttgg cacacttgct cgctacatat tcgtaatctt tcgcgccccg
     2221 cgtgcctcaa ggcccgacgg cgtcaaaagc ggtgccggtt agctgtccgg ttcagtcagc
     2281 tttgggctct ggctagcggt ttagccagcg gtcacgcccc cagtggaata ggtggcgtag
     2341 ccctaaacca agcagcgccc ccatcccagc acagggcaag gcgtagcgac taacttccca
     2401 gtaggcgata tcgagcatca gcgcgccgtg gaagaaagtg cgcgtggcgt cttcaaaaaa
     2461 cagcatcacc caggtggtta gcagcgccat ggccaccaca aaggggtagg aaataaaggc
     2521 gcgcacctgg cgaatttttg gcccggcaca gaaaaacacg gctagcagca taaatgggcc
     2581 cagtgagccg accccggtga aggaatctag gaactgtagc aatcctagtg ggatacgaat
     2641 ctgacccacc ggggtgtaca aataagagtg caccaccata tacacaatta gggtcactac
     2701 ctgcgaaaac gtaaaccagg cggtgtattt agccagggct agccaggtag gtacctgctc
     2761 atcttgcgcc ggaccaaagc caaccgcatg tgaaaaatca gggtcgacgg cgtcgtcgta
     2821 agttacgttg tcgggcaagt gatagctggc ccccgtagtg ctggtattac ccaattctcc
     2881 ccctgtaatg cctcgatgcc cttatcctag ttcagtgctg gtggatttaa ctatttagcc
     2941 agattatcct caaaatgtca gctatttagg agtcagttat gagtgcgtgt cctaccctac
     3001 cggttatggt cagcctggca cgcattgtca gccaaggttt agtgccagct accagcgcca
     3061 ctagcgtagt gcaggcagtt aacaatctgc tggcggtgca aggccaacag gtttcagccc
     3121 taccccacgc cttattggag cgcaccccgg gcgcaaagtt cagcgatgta accacagctt
     3181 ttaaccagtt agagttggtg cgctcgcgac caatgcgcgg cacggtacat attactagcg
     3241 ccgctgacta ccactggctt cggctaaccc taaatcagcg ctccaactat agtttgcgca
     3301 atcagtcgat cctagggggc attagtgaaa ctgacctaga gaccgcctgg cagctagtaa
     3361 aaacccatgc cccaacgcag ggcattagac gcaaagacat gtttgccctg tgggtgcaag
     3421 cgggcctagc tgttaaagcc caaaatgcca cttccctcaa ggctcccccc accaagcagg
     3481 cccgagttaa ccgctggtgc aatttgatga tgtggcagct ggatcgacaa ggtctagtag
     3541 tggaaggccc tatgggcacc aatgagcatc gtttcattga cgccacctgc ctacctgccg
     3601 ccaccagtgc ggctagtggc tttaaatttg atccagctga tctgcgcgcg gcgcgtatgg
     3661 aagtagctag gcgctacgcc tacgggcacg gccctgtaag cgtagctgat ctggctcgtt
     3721 gggccgcttt accggtaact caggcccgtc aagccctaga agatgcagtt agtaacagcg
     3781 agctaattgt ccgcgtaaaa atcgaggaaa atacatttac tcccgctgcg ccacctaaag
     3841 ttgtcaaaga gtataatcag ctgttatata tgcgcgcaga tttacctgat ctgttagcag
     3901 ataatctatc tcaagcccgc aggttaattt atttacccgc ttttgatgag ctgcatgtag
     3961 gctaccgcaa ccgcacctgt cttactgacg gcgcaggtga aaagcttatt tgtcctaccg
     4021 ctaacggttt atttaggccc ttaattgtta ataatggccg acttatcgcg gtacggccgg
     4081 catctagcgg ggttatctgg ttagacaaac ccacccctta catggacaaa cgagtaaata
     4141 aactagtcga caataggtta gaaagcttac aataggtcat aagcttgacc cctttcccta
     4201 ggactccaaa atgtcagccc ttactatttt tcataccggc agcgttatcg ttgacgaggc
     4261 tttgctctac cgtcgtccca gcgaccaccc gctagcttgg acccacctgc tacgtgatga
     4321 ctcacggtta gttgaggtac cggtatcgtg ctacctgctt gagggccgcc acgggcgcat
     4381 gctcattgac accggctggc acccggataa ccgcaccaaa ctaggccaaa tagctaacct
     4441 acgtcagcaa tacctcgcta aacgagcagt tttaccgcaa ggccaggcca ttgatgagca
     4501 actagcgcaa atggggatta gccccaaaga tcttgaccta gtgatgctct cacacctgca
     4561 ctgcgatcac gctgatggtt tgcggctagt taaagacgcc cccggcatta tggtctctaa
     4621 agccgagtgg tgcgccgcca agcgagacca cctgcgttac ctgccccacc agtggaagca
     4681 tgtagctatc aacacctacc catggaacac caagattggt ccttgggatg caggctttga
     4741 tgtctacggg gatggctccg tggttacagt ggccctaccg ggtcactcct atgggctaac
     4801 tgccaccatt attcgttctt ctaacatttc cagctccgac ccggcccgct gggtgcctaa
     4861 tgcttctggc gacggcgtcc acgacgggcg cgagttcatc ttgcttacct ccgacgccgg
     4921 ctatgggcgc ccctccctag aagaggatct acgtcccggc atggttatca aggccggctg
     4981 ggcgcgccgc tccctggatt ggattcgtca ggtgtctaaa gatccacgct gcctgcgcgt
     5041 aatcgccagc catgaccctg aaattattcc tgaaaccata cagctctagc gcggccctaa
     5101 accggctaaa gccccagttt gactgattta gctggcactt tctagcgcgc ctttaagcgc
     5161 cctagctggc cctacggttt aggcgtcaat gcgctcgcgg tctacctcgt cagcgctatc
     5221 aataataaat tcgcgcctag gcgccacact tgaacccata agaagttcaa aggtggattc
     5281 ggccagttct accgccgcct catcagctag cgtgattcgg cgcagcatcc ggtgttgggg
     5341 ttccatagtg gtttcagcca gctggtgggc gtccatttca cctagaccct tatagcgttg
     5401 gggttcttta aaggtgcgtc cctgcttttc tagcttgcct aaagtgctaa ccagctcttc
     5461 atcagagtag gtgtagataa tttccttctt cttgcgtccc ttagcgctga cctcaatgcg
     5521 gtgcagtggc ggtaccgcag cgtaaactcg ccccgcctca atcatggggc gcatatagcg
     5581 gaagaacagc gtcagcagca gggtgcggat gtgtgcgccg tcgacgtcag catcagtcat
     5641 caaaataacc ttgccgtaac gggctgagga aatatcgaag gtgcgtccac tgccagcccc
     5701 taccacctgg atgatggcgg cgcattcagc gttatgcagc atgtcggcgg cggaagcctt
     5761 ttgcacgtta aggatcttgc cacgaatagg cagcaaagcc tggttttcgc tgttgcgcgc
     5821 atttttggcg gtacccagcg ccgagtcacc ctcaacgata aacagctcag aggtagccac
     5881 gtcgtcgcta cggcagtcag ctagtttagc gggcagggtg gaagtttcca gcgcagtttt
     5941 acggcgggta atttccttat gcatccgggc acttacgcgc gcacgcatct cccccacaat
     6001 tttttcttgc agggcccgcg cctgggcttt aaggtcacgc ttggggctgt taagcagggc
     6061 ggttagctct ttttccacca ctgcggccac aatggctcgc accggggcgg tgcctagaac
     6121 ttctttagtt tgcccctcaa actgcggctc gggcacgcgc acggtaacca ctgcggtcag
     6181 gccagctaaa acgtcgtctt tttcaatttt gccgtcgcgc gagtttagct ttaaggcgcg
     6241 cgaattgacg ctgatctgtt tgcgcatcac cttaactaca gcctgttcaa agccagctag
     6301 gtgagtgcct cccaggggcg tggcaataat gtttacaaaa gaacgctcac aggtgtcgta
     6361 tccgatcccc cagcgtagcg ccacatccac ctggcaggtg cgctccacct ctaccgggcg
     6421 caggtgtccg cgctcgtcaa gctgctggac ggtctcgtta taggtaccct ggccggtgag
     6481 gcggaaagta tcggtcactg agccgtcttt cgccaggtag tcaacaaagt cggcggtgcc
     6541 ccccaaggcc aggtaggttt ggggtccggc gggtttgcgg gcgtcagctg cgtcagtttc
     6601 attgtcgacg acgacgctgc gctcatcgat tagccgcagg ctcagcccgg gcaccaaaaa
     6661 cgaagtttgg cgcagccggg aggctaaagc ggcgccgtcg tagtcattgg ggctggggaa
     6721 aatctgccgg tcagcccagt aacgcacccg cgtgccgcta accccacgct tgaccttacc
     6781 cacaacccgc agttcactgg cctcatcgaa ggcagtaaag gggctgttgg ggctcatgcc
     6841 gcttgaatca tcaaagattc ctggctcgcc gcgcctaaaa ctcatggcgt aggttttgcc
     6901 gccgcgatct acctgcacat ccatgcgggc agacagggcg ttaaccactg aggcgcccac
     6961 cccgtgcaaa ccgccggcag cgccatagag gccgccgccg aatttaccgc cggcgtgcaa
     7021 cttggtgtaa accagttcca ctccgctcag cccagtggaa ggctcagtgt ctaccggcac
     7081 cccacgtccg tcgtcacgca cctcaattga gccgtctgta tgcacgaata cgtcaatatt
     7141 tttggcgtaa ccttcaagtg cctcatcaac ggcgttatct actatttccc aaacgcaatg
     7201 catcagtcca cgctgatcgg tagaaccgat atacatgcct ggacgcttgc gaaccgcttc
     7261 taggccttct aaaacggaca gatgacgagc ggagtaggca ggggcttcgg acacgtgtac
     7321 aacctatctg attgcgccaa ttaatgcata ttgcgggtgt atctgtgggt gaacacactg
     7381 cgccaacagc aaaaataggg ctttagaagg acaaaatctt aaaaacctat gttggtatta
     7441 agccatgaat gttagcagcg tattgaatca gtcagctagc caggcggttg agccgctcaa
     7501 tgtggcagac cgctgcgacc tttgcggggc gcgcgcttac atgcgcgcgg tactaatgaa
     7561 cgggccgcta ctgttttgcg cccaccacgg caaggccaat ttagaggcgc tgcgcgccca
     7621 ggctttgcgc attgatgact ttaccgacga gctcgactga gcgctaacca ttgctcgact
     7681 gagcaccaac cattgactta accaacaacc aaagtaacgt ggccccctag ctaacagcta
     7741 gggggccacc gttaactctg gtatcagtcc aggtagtcgc gtagcacctg gctgcgtgag
     7801 gggtggcgca gtttgctcat ggtcttagac tcgatctggc ggatacgttc acgggtaacc
     7861 ccgtaaacct taccgatctc atctagggtc ttgggctggc cgtcggttag gccaaagcgc
     7921 atagacacca cgccagcttc acgttcagag agggtatcaa gcactgcgtg cagctgctct
     7981 tgcagcaggg tgaaggatac ggcgtctgcg ggcacaaccg cctcggagtc ctcaatcagg
     8041 tcaccgaatt cgctgtcacc gtcttcacct agcggagtgt gcagcgagat gggttcacgt
     8101 ccatactttt gcacctcaat gaccttttct tcggtcatgt ctagctctac agccagctca
     8161 gctggggtag gttcacgccc tagatcctgc agcatttggc gctgcacgcg ggccagcttg
     8221 ttgattacct caaccatgtg caccgggata cggatggtgc gggcctggtc agccatggcg
     8281 cgggtgatag cctgacggat ccaccaggtg gcgtaggtgg agaacttgta gcccttggtg
     8341 tagtcaaact tttctacagc gcggattaga cccaggttac cttcctggat caggtccaag
     8401 aacaacatac cgcgaccggt gtagcgctta gctagcgaaa ccactagacg caggttagct
     8461 tccagcaggt ggttcttggc gcgctgaccg tcttgggtaa tccagtacag ttcacggcgg
     8521 tatttgctgg tcagctctgc ggatttgtcg gccaggatgt gctcagcgta gaggccagcc
     8581 tcaatacgct tggctagctc cacctcttgg acggcgttaa gtagggcaac tttaccgatc
     8641 tgcttgagat agtccttaac cgggtcggcg gtagcaccag cggtgactac cttctgtgcc
     8701 ggctcgtcac cctcatcaga gtcgttaacg gtgtagccct ttttctcttc cttcttagag
     8761 cgcttgccct tcttcttggc gttagccttt tcggcctctt cctgacgcac acgctctagg
     8821 tcaccggtta gggcagcaat ggagggctgc atcttgatgc ccttaattac ccagccgcga
     8881 aataccaggc cgttttgggt caggaagtca cgggccacca tgggggctga gcccttgtag
     8941 atgaagcgcg gtaccgggcc gtgaccgtag ggagccaggg tgatgggctc ttccagggtg
     9001 ccgtcaccaa cgatctccag atccttaacc acagtgtgcg agcgcacaaa cagggtggag
     9061 ccgggggcta ggcggatgtc tttgaaagcg gcaggagtgt tgaacggtga ctttttagag
     9121 ccgtcaccat tgttttccag atttacatcc aggtagtagt cacgcttttc aggagcggga
     9181 gccggcgcgg gctcggcatc gtagtcgtcg ctctcctcat cggcatcctc gtcagagtcc
     9241 tgctcagaat cttcctcgaa gtcctcgtct accaggtctt cttcaaggga ttcgtcgtat
     9301 tcctcatcct ccgggtcgaa ttccagttca gcatcaaccg gcttgcgact agctttattg
     9361 ggagccacgg acatcctttc gcgcaccaaa acatcgacaa caggggcaat tttgccacta
     9421 tcttggggta caaccccgct agtttagctt ttattcccac cgtttcctat tttggttacg
     9481 caatgttcca acgctagtcg agcctagtag tgtaggtgac taccgggcag ggagcttcaa
     9541 gcagcaggcg ctgggcgtta ggacctatat tcataccgcc gtaacgtgag cagtgagcca
     9601 aaccaatcac cacgtaggag gcgtggtttt cgcgggccgc ttccagcacg aactcgctta
     9661 catccttacc gcgcgggcag ggctgcaccg cgtagtccag atcttcttga ccaagtgcat
     9721 catgaagcac ttccatcacc tggctgtcca cagccagatc gtcgccgcga tgcttttggg
     9781 catatacgca cagcagtttt tcgtctaaac gtttggccaa attcactgct tcaactaagg
     9841 ctgcccgtga ttccagggtc ccgtgatagc tcatgatgac ggccattttt ttgcacctcg
     9901 ttttgtatta tccctagtca aaggcggttt gactattatt tagcgtactc acaaagccag
     9961 cgcattacca caaatgtgac tgatcgccta tcgtgtagct atgagcgatc tgccggcaca
    10021 cctagctagt cttcgtcccc attttgatgc gcaggtatgt gcgcatcttg gggcgtatgc
    10081 cgattcgtgg cgcaacacgc aagcactaga tgaagttttt accatactct ctagtgcctt
    10141 ggcaggtggt aaacgtatgc gcgctatcct gggggctatt ggctacgcat acgccagtga
    10201 gtttggggct tacaaactgg ctttaacttc acctcaggca gcagcactgg gggcggcgct
    10261 agagttttat caggctagtg ctttagttca cgacgacgtc attgaccatg ccttaacccg
    10321 gcgcggccaa gtagctactc acgtggcttt ctccaagcta cacggtgata acggctggcg
    10381 cggcaacgat agcgattttg gtggggccgc agcgattttg gcaggtgacg ccctactagc
    10441 ctggggtggc gacttggtca cacaggctag tgaggtaact ggaaactacg gtgctgttaa
    10501 tgcttttaat cacatgtgtg cagaggtggc gctaggccag tacctagatg tgcgcaacga
    10561 aaaccttccc ctaaacggat cagatggcga gcaaatggtg tcccagtcac tagcagtcat
    10621 caaacacaag tcggcgcgct actcggtagc ttgcccgctg atcattggcg cgctactggc
    10681 aggagcgacc ccagatagcc cggctgtaaa agctctagaa acttacggcg aaaacgtggg
    10741 cgccgccttc cagctacgtg acgatgagct gggcgtattc ggctcctcca aagtcaccgg
    10801 caagcccgtt ggcgacgata ttcgtgaagg taaacgcacc gttttggtgg ggctgacctg
    10861 gcagctagca ggcgctaacg gccgcgccct gctcagcgac gtcgtcggca acacgaacgc
    10921 atctgagatg caaatcgcag ctgtggcaga cctaatgaag gactgtgggg cctaccaaaa
    10981 gcacgaacaa cttatcaacg actacctaac acgtggttta gcttgcctta gccatgacgc
    11041 tctaggggcc tcaattattg ccgatttaca ggttttagcc caggttttaa ccattcgcca
    11101 agcttaaatt caccaatttc ccagctgtag gccatgcgta gaatttgtta accccataga
    11161 ctagggcacg tgagtaaaga ttccgtttta ggccaggttc tagatgagcg ctatgaagtg
    11221 cgcgcacgct tggcacaggg cggaatggct gtcgtctatc gcggttatga ccaccgccta
    11281 gggcgcgagg tagccattaa ggttatgcac tcgcacctgg ccgataatga agctttcgtt
    11341 tcacgtttta agcgtgaagc ccattcggcc gcgcagctgt cggatgcggg gatcgttgcc
    11401 gtctatgacc aaggcaaaac cccctccgga cgcccatatc tggtgatgga actgatcgat
    11461 ggcattacca tgcgtaagtt catcgccact cgtggctaca cgcttggacg cgccattgag
    11521 ctaaccaagc agctactttc ctccctggaa accgcccacc aagtcggcat tatccaccgc
    11581 gacatcaagc ccgaaaacgt cctgctgccc actaacggta aaaccgccaa ggtagccgac
    11641 tttggtctgg cccgcgctgc cgacgccatc accgccaccg ctaccggcac ggttatgggg
    11701 accgtagcct atatgtcccc tgagctggtg cgtaccggta aggccggcac tagcgccgac
    11761 atatttgcgg taggcgttac cttctatgag ctactaactg gtacgcagcc ttttacggct
    11821 gacaccccag tacaggtagc tttactcaac gtaaatgagc ccattccggc tccctccaag
    11881 ctggtgcctt ggctgccgcc gcagatcgac gagattgtca gcgcgctaac caaccatgat
    11941 ttaaatattc gccccgccaa cgccactaag gctttggagc tggttgagcg tttagtggac
    12001 actattccgg ccaatgtgct caagcacgat ttggattctg aagaaagcca cactctggta
    12061 gaccccatgc cggtctctag ccagcacgta gctggagtaa atgtggggct acagtccggt
    12121 gcaccagtgg cctccaggtc ggcttattct gctgcctcgg ctccctctaa cttctctgct
    12181 accagcggta acagcgggca gtacagcacc cccagctact actccacccc cacctaccag
    12241 cctcagatgc tcgctatggc tgatactggc tggcagcaaa gctatagcga cgacgacgac
    12301 gatgagggcc tgcgtcgacg tggcctgctg gtgggtatcc ctaccgcact ggcactggcc
    12361 ggactggctg gaattggcgc ctacattttg gctagccccg ataaaccctc acaggtttca
    12421 attcctgacg taaccggtaa aacccaagac gatgcagtaa ccgccctaga cgatgtaggg
    12481 ctaaaagccg ccggtatttc agctagctct agcaccgtac ccaagggcca agtaattagc
    12541 cagcagccta ctgccggtac taccgccaaa accggtgata cggtcaccct aactatttcc
    12601 agcggcagct agggcagcta ggctgtgggt ttttggcgcc cgcgcgccaa aaacccaccc
    12661 tgcaccaaag cgttgagccc gcggcttgcc gtgggctcaa aactttaggt ggctttagct
    12721 acgcagcatt tctgccactt caaaggcaat ctctagggac tgctggtggt ttaggcgcgg
    12781 atcaaccagg gtttcgtagc gctgctctaa gtcagcttca gcgatatgct caccgccgcc
    12841 taaaacttca gtgacatcat cgccggtcag ctctacgtgt atacccccag gcacggtccc
    12901 aacagcgcga tgcacctgga agaaactgcg ggtttcagcc aaaatatcag caaaacgacg
    12961 tgtcttgtaa ccattttcag aagtaatggt gttgccgtgc atcggatcgc aaatccaggt
    13021 aaccggacgc ccgtcagcct taaccgcctg ggccagggct ggcagacgct cctcaatcag
    13081 gtctgccccc atgcgggtaa taaagctgat gcgcccgcct tcaccactgg ggttaagcct
    13141 atccataagc gcatagagct catcagggct agcgtcagga ccgatcttga ccccaatagg
    13201 gttacgcaca cccgaaagca gggccacatg ggcgccgtcg atgtcacggg tgcgttcacc
    13261 aatccaaagc atatgggcac tagtgtcgta agggtcgccg gtacgtgaat cttcacgcgt
    13321 catggcatct tcatagtcaa gcagcagcgc ctcatgggcg gagtagaaat caacttgggt
    13381 tagcgcccca aaatccaccc cagcggcttt cataaagcgc atagagcggt ccaactcccc
    13441 cgccatagtg gcaaaacgcg cataggccgg gttttcagta aagccccggt tccatgagtg
    13501 cacttcgcta agtgaggcat agccacccat ggtgaaagca cgaatcaggt tcagcgtagt
    13561 accagagcgt aaatatgcat ccagcatccg cttaggatct ggaacgcggg ctgacttagt
    13621 aaactcatgg ccgttaacgc aatcgccgcg ataaaccggc aaggttaccc cgttgcgagt
    13681 ttcagtatca gcagagcgtg gcttagcgta ttggcccgcc atacgcccaa ttttcaccac
    13741 cggcatggag gccccatagg taagcacaat cgccatctgc aaaatggttt gtacctttaa
    13801 acgaatagtg gtggcgtcgc ccttctcaaa cgactccgca cagtcgccac ccatcaacac
    13861 aaaagctttg ccctggccag cacgctccat atcagcccgt aaagaatcag cttcaccggc
    13921 aaacactagc ggcggacgac gtcgtagatc gttaaccacg tcagctaact gctggggatc
    13981 gggataggac ggttgctgag ccgccggaca cgaacgccaa tcaaagttac gcataggccc
    14041 aatcataagg gcaaaaaagg tggcccccac ataaacgtgg gggccacctc agtagcgttt
    14101 aagctcagtg ctccacagga gcgtcagaag cctcaacatg ctggccaatg ccttccatta
    14161 gacccttgaa ccagtcctgg tcgatgttga aaggcttgcc accggcaata cgcgggaacg
    14221 cgatggcggt tagcacgtca ccgttctcct cgtcctgacc gattacgcca ggctcgccgc
    14281 gcagagcgca gtcaacagcc aggtcgcaca tgctcttgat caggtctagg tcttcctggt
    14341 gagcggcagc tgcacgagag tagtagcccg acttctggac cataaccttc tcggcaccaa
    14401 tgagcttggc gaacttcttg gcgaaccact ggccggggtt gatggtgtct agcttgacgt
    14461 ggccgaaggg gtcacgctgt acctcttcac cagcagcctc tagctcggcg atgatttcgg
    14521 gaacgccagc accctcagac aggaagatgt tgacgttgcc ctgctcgtcc atgatggcct
    14581 ttagacgctc agcctcagcg gcgatgtcta gcttaacctc gggcaggtaa acagcgtgca
    14641 catcccagcg ctcgcgggtt agacccaggg agggggccca ctgcttggtg tctagcagct
    14701 gacggtagcg tagggcggtc tcagcggtta ggtaaccaca gttacgaccc atgcactcgt
    14761 gcacgatcag catgcggggg ttggagcggt gctcaccgat tacgttgaag gcgaagttgg
    14821 cgccttcgtc ggcggcagtc caggcaccca gggactgacg gatcggcact acgtcgttat
    14881 caatggtctt gggcaggccc actacggtta gctcgtagtt gtgttcgtgt aggtaggcag
    14941 ctaggtcagc agcggtggtg ttggtgtcat cgccaccgat ggtgtgcagc acgtccacgc
    15001 cgtccttgcg tagctgctcg gcagcgaatg ccagcgggtc tacgccttcg gctactagac
    15061 cacgctcaac caggttcttg gcgttggtca gcttgacgcg agagttacca atgggggaac
    15121 caccgaagtt gcgcagcagg ccagcgttct tacgggcctc ctcgtcaatg acgatgtagt
    15181 tgccggtcag caggccgtgg tagccgtact ggtaagcaat gatctcaacc tcgggagcta
    15241 cctcggtgta acgctcaatg aggtcaccaa cagcggcgga taggcagggg gcgaaaccgc
    15301 ccgcggttag aagggcgacg cgacgaaccg acatcgagaa cctttcaatt gtgggtgtat
    15361 atggcctgcg gccatagatt tctttactag tgtactcgct cacctttgtt ggtgcacgag
    15421 tcaaagggac tacttagctg agtcttcctc gctctgggcg gcaggctcct caacttcagc
    15481 tggaggctgg ggcacactag tcagtggggc ttggcggcca ccgggggcct gtaccggcat
    15541 agccagcggg ttggcctcag cctgggcggc cagcattttc tctaccactt cagcggcgct
    15601 gagcttgtca gcgtccatca ttttctttac gtctgcagcg tataggtcaa cgtattcctg
    15661 gccagagaga gccattaggg aatacatgat ttcgtcggtg atagaacgta aaacaaagcg
    15721 gtcgttttct aggccctggt aacggctaaa gtctaggggc tggccaataa ccaccccaat
    15781 gcggtgcaga cgcggcacta cctggccgat cggctgggca atattggtgc cgatcatggc
    15841 taccggcagc accggggcgc cggtagctag cgccacgcgg gccacaccgg ttttaccacg
    15901 gtagaggcgt ccgtcagggc tgcgggtacc ttcagggtaa ataccaaaaa gctcaccgga
    15961 gtttagccgg tcaatgccgg cttgcagggc cgccatcgaa tatttaccgc cgcgacggtc
    16021 caccgggatg gtgcccacgg aggtcataaa ctttttcacg ccccagcctt taagaccttt
    16081 accggtgaaa tagtctgatt taccaatgaa agccacctcg cgctcaatca tcagcggcag
    16141 gaagaaagag tcgataaccg ccaggtggtt ggaggctagg atagctggac cctcaacagg
    16201 aatatgttct tcaccacgaa tccagggttg atacatcatg tggatggccg gtccagccgt
    16261 cgccttaatc gcacggtatc ccatggaacc tcccaaaact cattagtgaa ctggcgccta
    16321 gcgcggctgg gcgcgtgtgg agacaagtgc tacattgata ttacagtttc gattgtgtcc
    16381 actgtagcta aagcgcccaa tcctgaccct aattaccctc accaggctag cttgctgcaa
    16441 atgggcacac ccttggagca agtaactttc gtggtggtgg acttagaaac caccggcgcc
    16501 cagcctggac ctgacgctat aaccgagttt ggggcggtgc gcgtacgcgg gggcgaaata
    16561 cttgatgagt ttggttcttt agctaatccg ggtacggctg tgcccgccta catcaccatg
    16621 ctcaccggca tcaccacctc catggtggct agcgccccgc cactagaaga agtgcttggc
    16681 gactttatga gctgggcacg cctagacgag cctgacacag tgattgtggc ccacaatgcg
    16741 cgctttgatg ttagccatct acgcagcgca gcgggagctt ttggatttga ttggccctcg
    16801 gtgcgagtgc tggatacttt gaaactgacg cgtaaggcgt ggagtcgcaa tgatgtggcc
    16861 aaccataagc taagtacttt ggcccggttt gtgggcgcgc aaactacccc tactcaccgc
    16921 gctctcgacg acgcccgcgc cactgtggat gtgctttatg cggccctaga gaaagtggcc
    16981 ctgcaggggc taacccatat ggaggattta actagcgcct gcgatccggt tcccgcctca
    17041 cggcgcgcta aggcagccat ggccgccgat ctgccgcaag cccccggcgt gtatcgcttc
    17101 tattcacccg gcaaccaggt gctttatgtg ggtagcgcca ctaatttgcg tcagcgtgtg
    17161 cgttcatatt tcaccgcttc agaatcgcgt gggcatattg ccaccatgct ggatgtggct
    17221 gaccgggttg agtatgaccg ctaccccacc ctgattgagg ctcgggtgca agagctgcgc
    17281 caaattagtt tctatgaccc gcccgctaac cgccgttcgc gtaaacacgc cactaaagct
    17341 tggttgaagc taactagcgg gccgcgcccg cgcctgtcga ttgttagcta cgttgactac
    17401 gagcagctaa gtaaaggtgg ggtaattggc ccctattctt cgcggcgcag tgcaaatgca
    17461 gctcgggtgg ctattgagga agtttttgcc ctagataggg tgggcgataa gggcattagt
    17521 gacactgtca gcgatgagga ctaccctgcc ctagctgatt tggcctacca ggctcttagc
    17581 gataatgcca ctttggtggt ggatccgctg atgcagcgta tccagacgct agctcaagcc
    17641 cagcgctatg aggacgccgg agtgatcact aagcgtttgc aagcttatgt gcgtggcctg
    17701 gagcgagtgc agcgtctgcg cccgctgttt acctgcccct atttggtttc ggcacgacga
    17761 cgcagcctag gtggctggga atttgtggct atcagccacg ggcagctact gggctctgcg
    17821 gtaagcccca gcggcgtcta ccccttagat gttttagccg agtttgaagc atttttaagc
    17881 cccatcaccc caccagagcg gatcatgggc acgcttatgc tcgaagaagc caaccttttg
    17941 gctgactggg ccctagatga gggggccagg ctagtgagtt tggatccgca agcgaaccta
    18001 tcgtggccga ttgattcgcc ggcgcggcac gccaaactac tagcccatgc ctaaattact
    18061 tagctagttg cttgcgcatt gcctgcgcca cggcctgagc taccgttacc ggatctagcg
    18121 gacgcgacac tacagcgtcg gcatgagccc atgcggaaag ccaaccgtcc tgggggcgcg
    18181 cggtgagcat aactaccgcc ggacgtgagt ccatttcggt aaggagttcg tgagctaaac
    18241 ccataccgcc gaactttttg acttcgctgt caaacactag agcagcaaag cgagtggggt
    18301 tctctttcag ggccaggcgc acagcttcag cggtggcaca ttcaaaccaa gtcactcgcg
    18361 gcaagccttt atctgggcgg cgtcctaccg cctcgatcac ctgcttgcga gtatctgaat
    18421 cgtctgaaaa caccagcagt tccacgctgt ctgattcagg cgctgaagtc atgttttcct
    18481 cctgggtggc ggcgccgcag gggacgcaca caaatgttcg cgttaagtgt atctttcaca
    18541 cctgcactaa ccaatttgta gctacactag agctaagcaa tttttaggac aaaagcccta
    18601 aaccacgttc tctagttttt caggagttta catggctatc tacaccctgc ctgaactgcc
    18661 ttacgactac gccgccttgg agccgcacat ctccgggcgc atcatggagc tacaccacga
    18721 caagcaccac gccgcctatg tagctggcgc caacagtgcc ctagaggccc tggccgctgc
    18781 ccgtgaagaa ggcaaccttg gcgctatcaa cctgtgggaa aagaacctag ctttcaacct
    18841 aggtggacac accaaccaca ccattttctg gaacaacctc tcccccaatg gcggcggcga
    18901 gcctgagggc gagctagctg aagccatcaa ggactctttc ggttcctttg aaaagttccg
    18961 cgcccacttc accgccaccg cactgggcat ccagggtagc ggctgggccg tactggccta
    19021 tgactccatc tcgggcaagc tagttatctt ccagttgttc gaccagcagg ccaatgtgcc
    19081 cgtgggcacc gtgccgctgt tcatggtgga catgtgggag cacgccttct acctggacta
    19141 cctcaatgta aaggctgact acgttaaggc catctggaac atcgccaact ggagcgatgt
    19201 agccaagcgt ctagacaacg ctgtagctaa cgccaagcag ctgatcctgg gctgaaaccc
    19261 accaagctaa actagcaagc tgaactagca agctgaacta gcacctagta aaacgtgggg
    19321 gcggctaccg tttggtagcc gcccctttgt atttactgcc atctttaagc tgctttaccg
    19381 gcctaaatgc tggttttagg cagcccaagc cctggcaccg gcccagactt agagggcctt
    19441 atttggcgca attaggcctt acttggcagc aatgtcgaat acgtaaactg acgcaggcgt
    19501 ggtctgtcca ccctggctgc tggcctgagg cggcaaaatg atcaccacgc ggctaccaac
    19561 cggaataccc gataggtcaa ccagctgctt aatctgggac actgacatct gtaccggctg
    19621 cggtgaggac tcagtccagc tagagcgctt gttgccatcc caggttgcca tcgccatgta
    19681 acccagggct gtgtcggtgt cggtgagctt ttcgccgtta ccgctagcta gcgtgatcag
    19741 cttggcggag gtgggggcgc taatgccagc cttaatagtg atcgaggggg cctggcccag
    19801 cttaccggtg acggtaatgc cgttcttttc cagctcttca gtggcgccct caaccagggt
    19861 ggcatcctta gaagcagccg aaatctgcgc cgtcgtcaaa gcatcagtta gttccacgta
    19921 gaacaccaag gtaccagccg gggcctgcgg gttagcgggc ttgtcaccgt aggctagctt
    19981 gccaggaatg gaaatctcaa gcacgtcgcc aaccttgtgt cccagcaagc cacagcgcca
    20041 accgtcaata acgccgttaa ggccaaagcg ggtagctgag ccgcgctcga aggagctgtc
    20101 gaaagtagtg gcagaatccc acttccaacc cgagtagtta gcggccacat tagagtcagc
    20161 agctactgcg gccccgctgc cagccttaat ggtcttaacc gtcaggttag tgggggcctt
    20221 agcaccctta acccaggtaa tagccggggc cttgttagaa ctgggctgac caatggtagg
    20281 tagcgcctta gagtcggtat caatcttcag cttagagcag tcaacttttt cctgcttagt
    20341 ggcggcgcta gcaggcgtgg cagcagcctt agcggacttt ttgccatcac cagagcaacc
    20401 ggctaggccc aagctggcag ccagcaacag cgccgctgcg gcggttagag atcgacgcac
    20461 aagatttcct ttgctttttt gtttgctatc gcgctatacc cccgccatca gctgcgatga
    20521 cgagggtata gcgggtggtt ttagtggaag gactcgccgc aggcgcacga accaaccgcg
    20581 ttggggttgt caatcgtgaa gccctgcttc tcaatggtgt cagcgaagtc gatagtggcg
    20641 ccgttgaggt aaggaatgct catgcggtcc acgattacct caacctgctt gccttcttca
    20701 ccaaaggcgc gaatggcgtc gccgtctagt acacgctcgt cgaagtaaag ctggtagacc
    20761 agacccgagc aaccgccggg ctgtacacct acgcgcagac gcaggtcatc acggccttcc
    20821 tgctcaagta ggctagccac cttggcggcg gcaacatcgg tcagcataac ctcatgggtg
    20881 gccacctcgt tggtggtttg gctcattgct actccttgat tatttgtctc ttgcgctcgg
    20941 gtcttaaccc aggcggttaa acatcagata tgcctatgct attcccgcta gggctaccta
    21001 agtgcactgg caggggctag cagcgaaaat ataggcgtga tttaggccaa ggtgactagt
    21061 tctaggtagt cctcactcca tagatcttcg tcaccgtctg gcagcag
//
