LOCUS       NZ_AUBE01000037        23231 bp    DNA     linear   CON 22-APR-2024
DEFINITION  Streptomyces flavidovirens DSM 40150 G412DRAFT_scaffold00035.35_C,
            whole genome shotgun sequence.
ACCESSION   NZ_AUBE01000037
VERSION     NZ_AUBE01000037.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces flavidovirens DSM 40150
  ORGANISM  Streptomyces flavidovirens DSM 40150
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 36790)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUL-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            environment                       :: Soil
            investigation_type                :: bacteria_archaea
            project_name :: Streptomyces flavidovirens DSM 40150
            sequencing_meth                   :: WGS
            ref_biomaterial                   :: DSM 40150, ATCC 19900
            finishing_strategy                :: Level 1: Standard Draft
            GOLD Stamp ID                     :: Gi11969
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2012
            Isolation Site                    :: Soil
            Sporulation                       :: Sporulating
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Unknown program v. before 2013-03-07
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000429085.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 01:37:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,525
            CDSs (total)                      :: 6,452
            Genes (coding)                    :: 6,216
            CDSs (with protein)               :: 6,216
            Genes (RNA)                       :: 73
            rRNAs                             :: 6, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 236
            CDSs (without protein)            :: 236
            Pseudo Genes (ambiguous residues) :: 0 of 236
            Pseudo Genes (frameshifted)       :: 106 of 236
            Pseudo Genes (incomplete)         :: 173 of 236
            Pseudo Genes (internal stop)      :: 25 of 236
            Pseudo Genes (multiple problems)  :: 59 of 236
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:04:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 323
            Orig. end                         :: 23554
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AUBE01000037.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..23231
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23231
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23231
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:13231](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13231)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            30..425
                     /locus_tag="G412_RS0129545"
     CDS             30..425
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS0129545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028815201.1"
                     /transl_table=11
                     /translation="MNDLGDAHLRTWTLHLIALLAADTREQLAWLGERELETKDVVEEV
                     ELVCRVSEGLAERGVFEPEDLRGLRALGRRLGKIDVTCRVGLWRNALATDSAWDGIRSL
                     ARQFLLTRLGDWRQPLPRPVRPHTGDH"
     gene            complement(643..885)
                     /locus_tag="G412_RS39935"
     CDS             complement(643..885)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS39935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157839193.1"
                     /transl_table=11
                     /translation="MAPGGTKTVAARTPVSLAGDLLATEHITMPITMLNIHEFTHPQEA
                     VPAMATMDAQTFLAQLNRVLPTAGRDETLPTLTGV"
     gene            complement(2054..2860)
                     /locus_tag="G412_RS36545"
     CDS             complement(2054..2860)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS36545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_037650246.1"
                     /transl_table=11
                     /translation="MTIEPFSTPERRPAADAAEARAITEGVRDALRVHARTGIVLARRV
                     RRAHAARVWTALGSPSWEAYARAELGVSRASAYRLLDMAVVLDQLDQAVTDLGMSPFGD
                     ILEITRQQAREIKGRVAEVAAVLADLLAERGPGLEPAAVARLLSAAVDKVRKTPPRREV
                     TTGMHAQEQRKERFEYWLGTVVLDTAPAHLTDADAAEALRAHDPELTTADTPSAAPTAS
                     VRTDRHTGRQVQSAGKDAQGVTGSQPVRSRSRMKRSPARGPGAEAS"
     misc_feature    complement(2851..2871)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.12"
                     /tool="antismash"
     gene            complement(2953..3132)
                     /locus_tag="G412_RS0129560"
     CDS             complement(2953..3132)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS0129560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028815203.1"
                     /transl_table=11
                     /translation="MALLFFGTDPNSGGGNCPAVWVDADTAQGPELVLHGKFADAATRA
                     TCRQDSPPADGSVI"
     misc_feature    complement(3124..3126)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3340..3996
                     /locus_tag="G412_RS40595"
     CDS             3340..3996
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS40595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_244283299.1"
                     /transl_table=11
                     /translation="MRRTEYDAGQAAKHLKVPAAAFRWARHTGSDPGPGRVVLPVVPGR
                     RGGAGRRRHPAAMPSPPISGGATADRIADALGTPNRTIHGAKANVTAFVVRRFVDRGLL
                     VDLSANPDGTLHHPGQVAEVCRRENLADLIAADTPLGPEQAAARLRVRRTDSDHMVRLS
                     WIRSPQSIEVRFGTSRAGAVDVALYTTASVDAVPAEHPEVDCRPAPRCTERPVGS"
     gene            complement(4047..4379)
                     /locus_tag="G412_RS39940"
     CDS             complement(4047..4379)
                     /EC_number="1.11.1.6"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS39940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="catalase"
                     /protein_id="WP_028815204.1"
                     /transl_table=11
                     /translation="MSDKHNSKPTEAPSNTKPQPKPATVTLGARGGTAVLVAVGGNTIP
                     ATLTVVDASGTPVAIYTAGPAGPQITTRNMVLTTNDGQPVDNNQNALTLGPDGPTLLAD
                     FQFVEK"
     misc_feature    4386..4400
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.48"
                     /tool="antismash"
     gene            complement(4584..5576)
                     /locus_tag="G412_RS0129575"
     CDS             complement(4584..5576)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075312.1"
                     /locus_tag="G412_RS0129575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase III
                     C-terminal domain-containing protein"
                     /protein_id="WP_028815205.1"
                     /sec_met_domain="fabH (E-value: 3e-37, bitscore: 119.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVYSRITHVAVHLPDGRQSVRAIEDRLREHSPGVRVPAGLLRRL
                     YGLEERVVAADGDVPSGLASHAVARVLNQAGLEPGEVDLLLFAAVSADVQEPANAHIVA
                     AQAGLSCPVFDVSNACNSVLNALEVADAFIRAGRYRRILIACGETLSRLSRWNLTPTTL
                     RTGLASLTGGDMGAALLVEASTRPGIIAHTFMANSAGWSAATLFNPHHAPDGPPGLHID
                     SEKLLASFLGIDTRAAQWLKEQHADPNELGLVCLHQPSVPFVRTFCERLSIQPDTVVPT
                     FHRTGNMGAATLPLQLAHAADQGRLRPGTQVVLFGMASGASGGVMLISW"
     gene            complement(5573..6478)
                     /locus_tag="G412_RS0129580"
     CDS             complement(5573..6478)
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (13-176). E-value: 2.3e-12.
                     Score: 39.2. Matches aSDomain:
                     nrpspksdomains_G412_RS0129580_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012334.4"
                     /locus_tag="G412_RS0129580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_078607512.1"
                     /sec_met_domain="adh_short (E-value: 3.4e-36, bitscore:
                     116.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMHASTGLRVQRSVMVTGATGGIGAATALRLAGCGFDVIGTARS
                     QEKADGLLAAAAARGRPLRTVVLDVAEPSSCEEAMGRIAEMTGGGLWAVVNNAGVPQAG
                     SLEDVSDEQARYLLEVNLLGAMRICRLALPQMRRRGEGRIVNVSSGLGRVPWPLGGWYS
                     ASKHALSALTHCLRVEMAHAGVRVSLVEPGAFATAMLDRAIDDLAQVDRGGAAGYDRSK
                     SLFGAVNARVPGPEPVARTIEKALTSPRPRARYTVGFDARLLVPLHTVSPLWLSDWVKH
                     TVSGLPHKAPAYAGMVKESV"
     aSDomain        complement(5951..6439)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G412_RS0129580_PKS_KR.1"
                     /evalue="2.30E-12"
                     /label="G412_RS0129580_PKS_KR.1"
                     /locus_tag="G412_RS0129580"
                     /protein_end="176"
                     /protein_start="13"
                     /score="39.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="SVMVTGATGGIGAATALRLAGCGFDVIGTARSQEKADGLLAAAAA
                     RGRPLRTVVLDVAEPSSCEEAMGRIAEMTGGGLWAVVNNAGVPQAGSLEDVSDEQARYL
                     LEVNLLGAMRICRLALPQMRRRGEGRIVNVSSGLGRVPWPLGGWYSASKHALSALTHCL
                     "
     CDS_motif       complement(6371..6436)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G412_RS0129580_0001"
                     /evalue="3.60E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="G412_RS0129580"
                     /protein_end="36"
                     /protein_start="14"
                     /score="13.2"
                     /tool="antismash"
                     /translation="VMVTGATGGIGAATALRLAGCG"
     gene            complement(6613..6765)
                     /locus_tag="G412_RS39945"
     CDS             complement(6613..6765)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS39945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157839194.1"
                     /transl_table=11
                     /translation="MTTGRTSSWRSPGMLCDPTVFTDRVAAPRRPPGLVVRPTAGQKRF
                     ALAKA"
     gene            complement(6762..7166)
                     /locus_tag="G412_RS0129590"
     CDS             complement(6762..7166)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018106135.1"
                     /locus_tag="G412_RS0129590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028815207.1"
                     /transl_table=11
                     /translation="MSTATTELRRFLTITGQRFKSGLSAPEMFSPAVDAAWHELLGTPA
                     YAALCLETAGQPIRHVANNGHGPIAWVAAYEEAYGPLPEIWFTDADGTVDEDAIARYRE
                     TGTVVAEWDCGPAGGDGDDVAPDQPETARR"
     gene            complement(7677..7865)
                     /locus_tag="G412_RS38705"
     CDS             complement(7677..7865)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018555018.1"
                     /locus_tag="G412_RS38705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_078607514.1"
                     /transl_table=11
                     /translation="MSAPTPADTQPEDHGLQPPAFGQPSPALLARADRGYARFLAIHGP
                     AADTGDHDQDDDAEGAR"
     gene            complement(7967..8815)
                     /locus_tag="G412_RS0129600"
     CDS             complement(7967..8815)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677568.1"
                     /locus_tag="G412_RS0129600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_028815209.1"
                     /transl_table=11
                     /translation="MPASPSSSAQAAREALAVRLTHLRKDAGLTGKELSARCGWHPAKT
                     TRIQKGAVLPSDADIRTWCTACGADDQAADLIATARAVDSMYMEWRRLHRNGMRQVQQD
                     WYTLHEQTRHCRVYLSNVPPGFLQTPAFATALMKQITRFQGTPDDVTEAVAARIARSRF
                     LYEGGHRYVVLIEESVLRYRTADPEAMRGQLRHLLAVMPLASVSLGIIPFTAQRTVWPL
                     EAFYVHDDTTAVVETLTAEIKVTQPREVADYTKAFARLQEMAVYGDTARALIQAAIDAL
                     E"
     gene            complement(8824..>9312)
                     /locus_tag="G412_RS36560"
                     /pseudo=""
     CDS             complement(8824..>9312)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677567.1"
                     /locus_tag="G412_RS36560"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DUF6879 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="THRTAVHLEMRVVYAVGDERDDFESFLVPNLDPARSFWPQWMPLV
                     KDAVARGVVMRRARIVSEPVTDYIRYEHAITPLNLQAGEDLRWLPRRQASDIPLPGNDF
                     WLLDGRVVQFHHFTGTGDWAPDGKERTDDPAAAALCATAFEAVWERGIPHEKYTVQAP"
     gene            <9315..10031
                     /locus_tag="G412_RS41220"
                     /pseudo=""
     CDS             <9315..10031
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010286546.1"
                     /locus_tag="G412_RS41220"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DDE-type integrase/transposase/recombinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="EEAQPRVAHELGIAADELAGLHRRFEVIPGAQAQVDWGDEGKVLA
                     HVGLPKVYSFHMVLSYSRDPFCCFTTSQDLATFFDCHRQAFTHFGGVPMTIVYDRTKTV
                     VGVHVNFKEYADNVVAHSCAHRPSSSTESRSRGPRRLEGLAHAARCGPASASFCRRDVR
                     PALRAGARQWAATAGRSWGPSSGRARTAACAGQAGARRATSPGAQSGAAPVRVVDASLV
                     PGLAALVHCRVVGSSW"
     gene            complement(10001..11038)
                     /locus_tag="G412_RS0129610"
     CDS             complement(10001..11038)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="G412_RS0129610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028815210.1"
                     /sec_met_domain="T1TS (E-value: 1.6e-50, bitscore: 164.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHTIDTGAVYELAAIPLRLARQRHPAITKLERWHDLWLTEHYPF
                     PTDRARDTFLAQRSALWTAFTYPVTDEDRFHDLARLTSFLFAFDDLFLQSSPDSSTDVE
                     QVLNDTLHVMQGGAPATAHGRALADVWQAMAQRMPARQRHRLTEAARGFARGCLREVSS
                     RAQGSVLDLASYTSVRLEQSLAAWVYFILTEYAAGVDLTDPVLARLRSLHWACAEHLLF
                     SNDLFSFRAEHFAGDHVNAVCVLLTAGATLQQAIDKLVNLVALKEQQIADMLTTLRSSR
                     LGADCAVAAYLHNLEYVISGNLEQARFAPRYHGTADFIDRPIARGTVTLHSDRTDHQLL
                     PTTRQ"
     gene            complement(11035..12045)
                     /locus_tag="G412_RS37460"
     CDS             complement(11035..12045)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="G412_RS37460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="terpene synthase family protein"
                     /protein_id="WP_028815211.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-50, bitscore: 164.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSLAEIVRPRRFRLPDRFTAHSPYAQSMAPQYDTWCDQFIHLPE
                     EGRARYRRQRLDLVTAYSFPHSLSHERALTTALFSLWATHLDDHFGTSSPAELAALRRR
                     VGEILDGARPRTDEHPVLRMAADLRVMATELMPPHWLSRFSRENHENFIQKGIEAEAPF
                     KLDQRVPSLAELEEFRPYSVGMYPWLTLVELELGVPLPDHIATHPAIRRAMHLLARITA
                     WQNDAYSMPKEIPRSGDGETINLAFVLQREDDLSLEQACDEMLRIHDADLAEFVALADA
                     LPDFGADQPDVERVVHHMALATSGVTTWYQLFGANRYSDDGWVESPKREGMGLLP"
     misc_feature    12021..12035
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     gene            complement(12083..13231)
                     /locus_tag="G412_RS0129620"
     CDS             complement(12083..13231)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957287.1"
                     /locus_tag="G412_RS0129620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_244283300.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.5e-50, bitscore:
                     160.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSENADFAPAAVPGSQRQCPMPAPAAVDVTLLDLRGVRHAVDTVL
                     DTFLAEKRRTESACHLPRETGEALHALLFSGGKRLRPLLCVLGWYAASGQEDITPVLHA
                     AASLEMFHTFALIHDDVVDRSATRRGRPTLHRVLADLHRGARSQAQAEHLGISTAILIG
                     DLALAWSDELFPTTCLTPAQLAAALPVVENMRTELMYGQYLDVVAAGRPTSDIERAMEI
                     VRYKTAKYTVERPLHIGAALAGTAADTRSALSAFALPLGEAFQLRDDLLGVFGTLDTTG
                     KSCMEDLRDGKHTVLLAHALQRADPVQRQALEKLVGDPGLDEGGAARIRDILIATGARD
                     SVEHMITSRRERALRSLDTGPFPLAATDALRQIAYDTTTRVA"
     gene            13909..14925
                     /locus_tag="G412_RS36570"
     CDS             13909..14925
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1213: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS36570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_244283301.1"
                     /transl_table=11
                     /translation="MAIIAHPPGEEIQFDWVELPDPPVEWGVGANAHLLVGALAHSGRW
                     RAVLAEAETFPHLVQAIDAVLRRLGGTARRWRFDRMATVCHPPTGRILPTFASVAKYYG
                     AGVDICPPRRGNRKGVVEKANHSAAQRWWRTVPDGISIGAGQNGVDKLAVQMDSRKRKL
                     DGASTTVAALAEAEPLLDLPPRPFPAELEQIRVVSPQGLVFFAGNHYSVPPGLVGAHVT
                     VRIRLGEDDLHVVTASRAVIAHHRRAPDGAGQTVRDSGHVVALERAVLASFSDKAPCRT
                     KVRRPPSAAAQAEAEKLRGRPESDVANRVVIDLSHYAAVADRLRQAPTHEDQECESE"
     gene            14936..15444
                     /locus_tag="G412_RS41480"
                     /pseudo=""
     CDS             14936..15444
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013828.4"
                     /locus_tag="G412_RS41480"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSEARRYQQLRGHLSYLKLNDAAEALPRVLDQARAERMTLTTALE
                     KLLEIEVEATEARKLSSRLRFACLPEPWTLNDFDFAAQPGVEENSSATWPLCGSSITPP
                     TSCWSARPASARRCWPSHSLAPRSTLATASTSPPPPNSPPSVTRPPSKAAGRAS"
     gene            15441..15725
                     /locus_tag="G412_RS41485"
     CDS             15441..15725
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013828.4"
                     /locus_tag="G412_RS41485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_028815213.1"
                     /transl_table=11
                     /translation="MIDELGYLPLPGDGASALFQVINQRYLKSSTILTTNVGIADWAGA
                     FGDATVAAAMLDRLLHRAAVVGIDGPSYRLRSHQSHADNLRKGVTGRAG"
     misc_feature    15863..15878
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            16120..16449
                     /locus_tag="G412_RS0129640"
     CDS             16120..16449
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895668.1"
                     /locus_tag="G412_RS0129640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028815214.1"
                     /transl_table=11
                     /translation="MALVKKGSRLITVDGMTYRWRLRGRPTYDQGLVRSPLTYAVEHAD
                     ASGTTLVVTTNKPHPSNWFGTQGSPILPGQVADSIRTALSDGWTPEGPGSPFHLDQSAG
                     FVSPH"
     gene            complement(17075..17263)
                     /locus_tag="G412_RS0129645"
     CDS             complement(17075..17263)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009717477.1"
                     /locus_tag="G412_RS0129645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cold-shock protein"
                     /protein_id="WP_028815215.1"
                     /transl_table=11
                     /translation="MRWFNAEKGFGFIAPDGGGPDVFVHYSALGGSGFTSLYEGQRVEY
                     EVAQGQKGPQATDVRVL"
     misc_feature    17746..17758
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            complement(17752..18135)
                     /locus_tag="G412_RS0129650"
     CDS             complement(17752..18135)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS0129650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028815216.1"
                     /transl_table=11
                     /translation="MKLRTFACAIAVTLTFAGVGQGAAPAWAGGIGDFLSPAIGNGCAN
                     QRVGAAAQGGTTAATGHGAGNLLTLPTTGPLNQCGGADLPLHDSFNAKNCAHENGKSDA
                     QLVQLKEILNQESDTGKSNNLVC"
     misc_feature    complement(18383..18397)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.85"
                     /tool="antismash"
     gene            18430..18609
                     /locus_tag="G412_RS0129655"
     CDS             18430..18609
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS0129655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028815217.1"
                     /transl_table=11
                     /translation="MRRAAAVILTAGALLTTLTTTTAAANPADPWPPIQLPEIQLPTLP
                     EMPEIPGVPEPESS"
     gene            complement(18782..19744)
                     /locus_tag="G412_RS40610"
     CDS             complement(18782..19744)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980061.1"
                     /locus_tag="G412_RS40610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028815218.1"
                     /transl_table=11
                     /translation="MSDDYGYQVRRLETRTGGMEHELHSLRSKLGEVEDLDYELRDIRG
                     DIRSLEDDLSTVRNDLTELDDDVRGHIQGTDQSLKRLTGRVQALEAHLLAAGGAPLADL
                     DTIDPEWMKLARTANHGWHVRSGLLPRHQREAHRIKVREYEGAIAERDEHRDKVVEAAG
                     ILATQPRTSREFKQAVMDFGMSHTLAERHDQRARKLAGPAQTAQAALAQDDSLRQAKAS
                     LIEQGDKAERKLNWLLRSRLAEAIRDRALLPMWFVTVLGPVPPAHKTQEWMDLATQVLA
                     YRVTYGITDQVVALEPAPDEYVPRRTEWYLELTKDLRRW"
     gene            complement(19741..20277)
                     /locus_tag="G412_RS0129665"
     CDS             complement(19741..20277)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS0129665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_028815219.1"
                     /transl_table=11
                     /translation="MGSTEQKTEEQFAQLQQKVGARHAEVLKHSDGDQFAVEYARLVNV
                     TSKLVEFEKTIPERLAEPDRRRSERIVTWSWRGQAAVGAVLIALVFVLDHSTWWLVLLV
                     PHFVGTVAGCFQKVDAEQHRDRRFGAVALHVVALLMALISLSVISRWFIIAAAVGWMLV
                     AGSSMDSTDAKGARR"
     gene            <20536..>20709
                     /locus_tag="G412_RS38715"
                     /pseudo=""
     CDS             20536..>20709
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086896515.1"
                     /locus_tag="G412_RS38715"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIT"
     misc_feature    21195..21210
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.77"
                     /tool="antismash"
     gene            21264..22889
                     /locus_tag="G412_RS0129675"
     CDS             21264..22889
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013714.4"
                     /locus_tag="G412_RS0129675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_078607516.1"
                     /transl_table=11
                     /translation="MRPTAPTGSAVVKFGGPARTGAFVVMSAEGAMVVSRRRVLWGGAQ
                     ALALASAGRMTAGVAQAVPVRHTPTWEGSLPASSWRSLERALSLGAGLYRPGNANYQKL
                     VLPDNRRYAAVRPAGITACATEKDVRAALGWAADHGMPFAVRSGGHNYAGYSTTTGLLI
                     SLRRMRGVVPSGHRLVLGGGATNSDVYEAKAANLYFPGGRCPGVGVAGLTLGGGLGFND
                     RKWGLTCDRLVETRLVLADGSLVRASARENADLFWACRGGAGGNFGINTGFTFEAVDVS
                     AQRATVFDLTFPVRQGVEVMAAVQEALAADEHNALDVRIGFKNEGQGNGGTLWLLGQRL
                     GGQDSLQRALAPVLSLRPKKAFVQERHFWDAQDYLMERPGTPAASASKSLVPDSHIGRP
                     AVEDIIGWIEDWQPGQRGNAGYVTLFAMGGSSAQPGNGETAYPHRRGTFVIDIGSHWHT
                     DTPRQTVDGLLAQLRTMHRTLRRGLETSAAYVNFPDPDLHDWQHAYYGANYERLTDVKH
                     HYDPTGLFRYGQSIGVADTATAHP"
ORIGIN
        1 actggagtac taagtgagat cctgcctgaa tgaacgatct cggcgacgcg cacctgcgca
       61 cctggacgct gcaccttata gccctcctgg cagccgacac ccgagaacaa cttgcctggc
      121 tgggcgagcg tgagctagag acgaaggacg ttgttgaaga ggtggagctc gtctgccgcg
      181 tctccgaagg actcgcggag cgcggcgtct tcgagcccga ggatctgcgt ggtcttcggg
      241 cccttggccg tcgcctcggc aagatcgatg tcacctgccg cgtcggcctc tggcgcaacg
      301 ccctggccac agattcggcg tgggacggca tacgttctct cgcccgccag tttctcctca
      361 cgaggctggg cgactggcgt cagccactgc cacgtcccgt gcgcccgcac acgggcgacc
      421 actgagtcgg ccaggcctcc tgtgcgactc tgacccggtc ggcgccgcac acggatgggt
      481 gccgggtgaa gcagcgttcg aatccttggt gtgctctggt gcctcccgaa gtcgtgaaca
      541 tctgctgtcc gtcctcatga acaaagccac ggggacttcc gcgaccgcga agcggtagca
      601 gtcggtggcc gccaaggcga gcgtctcgcc ctccagggtc atctagacac cggtgagggt
      661 cggcagggtc tcgtcgcggc ccgcggtggg cagcacgcgg ttcagctggg cgaggaacgt
      721 ctgcgcatcc atggtggcca tggcgggcac ggcctcctgc gggtgcgtga actcgtggat
      781 gttgagcatg gtgatcggca tggtgatgtg ctcggtggcc agcaggtctc ccgcgagcga
      841 gacgggcgtg cgggcagcga ccgtcttggt tccgcccggc gccacgcgag cgccctcact
      901 gaccaggacg tccacccttg gcgcgcggtc gcggccgccg tcatcgcggg ggagatcgca
      961 ctgctacccg cactgctcat cccgcggacg atgccgtacg ccgtggccgc cggcatgtga
     1021 tgcacgcggc cttcacctgc ctcaagcccc gccagctcat caccttctcg gggctaacgg
     1081 ccggtactta cgttttgcct tcaccgcgtg agcgtccacg tcggcgcaga ctgccacctc
     1141 cgccgttcgg ctcagccaca ctatgcgccc gcgtccccca gcgcgggtcc tccccggcgc
     1201 cgccccgtcg cacagccggt gacgggggag ccccgtaccc ccgaaaggcc tgaggagctg
     1261 accacgcccg acgaggacac cgctgagggg cccgtggcca cgccgaccgg cttgtaggcg
     1321 atcttcgagg ctttcagggg tgccccgaga gcggcggatg aggaggttca gggcttgagg
     1381 tcactgtcgt cgaggtgact gccaccatgg cgtcggggcc caattgctcc agcaacctaa
     1441 tgtaggcgtc ggccgtgttg cccgccacta ggtgtgtatc ggcaagaaca gcgacccaat
     1501 gcccctcaga cggagggggt gcgagggtcc acgtgacctt ccagctgcca tcgcgcaaga
     1561 tctcggcttt tggcgagacc agccactcgg caccaaatgc aattcctccg gaatctgtgt
     1621 cggatgtccg aaccatgacg tggactgcca tgcccggggg tgcgttggtg actgtcccag
     1681 agaacacgta cgtcttgctc ggaggagtgg caggtgtctc tgtccacgag gtgatgctga
     1741 ccctggggcg gggggcaggt gcgggtcggg gttcgacacc gccgcccgca ctcagcgcca
     1801 acagcccggt gagcagcgcg gcaagcaccg ctcctgcagc cccgatcaga gccgctttgg
     1861 atgagggctg ccagcgctgc cacggataga cacgctgagg tgacggggca ggcgcaggtg
     1921 tcggtgggtc aggctcgggc gtttgcgggt cagaagatcc gctcgtggtg cctctactgc
     1981 ccccgtcgct gctgccctcg cccgccagcc ccgttgtcac cgaactcccc cagttccgat
     2041 gctgcacgcg acctcatgat gcctcagcgc caggacctcg cgcaggcgat cgcttcatgc
     2101 gggaccgtga ccgcaccggc tgggatccag tgaccccctg cgcgtcctta cccgcggact
     2161 gcacctggcg cccggtatgt cgatctgtac gcacactcgc tgtgggcgct gctgacggtg
     2221 tgtccgcagt ggtcagctcg ggatcgtggg cgcgcagcgc ctcggcggcg tctgcatcgg
     2281 tgaggtgggc gggagcggta tcgaggacca ccgtgccgag ccagtattcg aacctctcct
     2341 tgcgctgctc ctgcgcgtgc atgccggtgg tgacctcgcg gcggggcgga gtcttgcgga
     2401 ccttgtccac tgcggcggac agcagccttg ccaccgcggc tggctccagc ccggggccgc
     2461 gctcggcgag caggtccgcg aggacggccg cgacctcagc cacgcgaccc ttgatttccc
     2521 gggcctgctg gcgagtgatc tccaagatgt ctccgaacgg agacatcccg aggtcagtaa
     2581 cggcctggtc gagctggtcg aggacgaccg ccatgtcgag cagccggtag gccgacgccc
     2641 gtgacacccc caactcggcc cgcgcgtacg cctcccagct cggggagccc agggcggtcc
     2701 agacccgcgc ggcatgcgct cggcggaccc tgcgggccag gacaatgccc gtccgggcgt
     2761 gcacgcgcag ggcgtcccgt acgccctcgg tgatggcccg tgcctcggcg gcatcggctg
     2821 cgggacggcg ctcaggggtg gagaacggct cgatcgtcat accgactcaa cgagtacccc
     2881 gcacgaacag gacgtgcctt acgtgccgca acggcaggga cacccgtgag ctgcgcgttc
     2941 gtccctcgtc ccctagataa cgctgccgtc tgcgggcggg ctgtcctgac ggcaggtggc
     3001 ccgggtcgcc gcgtcggcga acttgccgtg caaaaccagt tccgggccct gggcggtgtc
     3061 ggcgtccacc cacaccgccg ggcagttccc tccgcccgag ttcgggtccg tgccgaagaa
     3121 aagtaacgcc atgatcccct ccgaagcgag ccggttgcgc gtagttgcgt gacgaccgtc
     3181 ccgcgccctg cccgcccggt caatatcgca gaccggggcg ggccatcgcc cggccatccg
     3241 gacgggtgat ttcccttcgc gtacgcgggc gccagcccta gcggcgcacg tccaacttgc
     3301 gtgctttcaa ggggccttgg gtgagaggtg atcgatctca tgcgacgaac cgagtacgac
     3361 gcgggacagg ccgccaagca cctgaaggtg cccgcagccg ccttccggtg ggcccggcac
     3421 accggttctg atcccggccc cggacgggtc gtcctgccag tggtcccggg ccgccgtgga
     3481 ggcgctggac gccgacgcca tccggccgcg atgccctccc cgccgatctc cggcggcgcg
     3541 acggccgacc ggatcgccga cgcgctcggc accccgaacc ggactattca cggcgcgaag
     3601 gcgaacgtga cggcgttcgt ggtgcgccgg ttcgtcgacc gcggcctcct ggtcgacctg
     3661 agcgcgaacc cggacgggac gctgcaccac cccggccagg tcgcagaggt ctgccgccgc
     3721 gagaacctgg cggacctgat cgccgccgat accccgctcg gtcctgagca ggccgccgcc
     3781 cgccttcggg tccgccgtac cgactccgac cacatggtcc ggctcagctg gatccgctcc
     3841 ccgcagtcga tcgaggtccg cttcggcacc agccgggccg gagccgtcga cgtcgcgctc
     3901 tacaccacgg cgtccgtcga cgcggtgccc gccgaacacc ccgaggtcga ctgtcgcccc
     3961 gctccacgct gcacagaacg acctgtcggc agttagggca cgacctatcg gacacgccct
     4021 gagtagatcc gcccggacgg gtgtatctac ttctcgacga actggaagtc cgccagcagg
     4081 gtcgggccgt ccgggcccag ggtcagcgcg ttctggttgt tgtcaacggg ctggccatcg
     4141 ttcgtcgtca ggaccatgtt cctcgtggtg atctgcggtc ctgcgggtcc ggcggtgtag
     4201 atggcgaccg gggtaccgct ggcgtccacg acggtcaggg tggccggaat cgtgttcccg
     4261 ccgacggcaa ccagcacggc ggtgcccccg cgggcgccca gcgttacggt ggccggcttc
     4321 ggctgtggct tcgtgtttga gggtgcctcg gtcggcttgg agttgtgctt gtcgctcatg
     4381 tcaacattct ccagaaattc aaagggaata ccagctcgcc tcaccatacg aacaagacgc
     4441 gccgcggatg gtcgagcagg ctcgcgccaa acgccagcgg tcccggccag ggactgcgcc
     4501 ctttccgtga ccctggagcc tgtcggccgg cccctgttgt cacgagtgtg agggcgtggg
     4561 ccacggtgtc tatcagctgg tgcctaccag ctgatcagca ttacgccgcc gctggcgccg
     4621 ctggccatgc cgaacaggac cacctgtgtg cccgggcgta gccggccttg gtcggcggcg
     4681 tgggcgagtt ggagggggag ggtggctgcg cccatgttgc cggtgcggtg gaaggtgggc
     4741 acgaccgtgt cgggctggat gctgaggcgt tcgcagaagg tgcggacgaa gggaacggac
     4801 ggctggtgga gacagaccag gccgagttcg ttcggatcgg cgtgctgttc cttcagccac
     4861 tgcgcggcgc gggtgtcgat gccgaggaag gaggcgagga gcttttcgga gtcgatgtgc
     4921 agtcccggcg ggccgtcggg ggcgtggtga gggttgaaga gggtggcagc cgaccagccc
     4981 gcggagttcg ccatgaacgt gtgagcgatg atgcccggcc gggtggaggc ttcgacgagc
     5041 agggcggcgc ccatgtcccc gccggtcagg gaagccagcc cggtccgcag ggtggtggga
     5101 gtgaggttcc atcggctgag gcggctgagg gtttccccgc atgcgatcag gatccgccgg
     5161 taacggccgg cgcggatgaa ggcgtccgcg acctccaggg cgttcaggac gctgttgcag
     5221 gcgttggaga cgtcgaagac cggacagctc agtcccgctt gggcggcgac gatgtgggcg
     5281 ttggcgggtt cctggacatc ggcgctgaca gcggcgaaca gcagcaggtc gacttcgccc
     5341 ggttcaaggc ctgcctggtt caggacacgg gcgacggcat gggaggcgag gccagagggc
     5401 acgtcgccgt ccgcggcgac gacgcgctct tccagcccgt agagcctccg cagcaagccg
     5461 gccggaaccc gtacaccggg gctgtgctca cgcagccggt cctcgatagc tcgcacgctc
     5521 tggcggccgt caggcaggtg gaccgcgacg tgggtgatgc ggctgtagac gttcataccg
     5581 actccttcac catgccggca tacgccgggg ctttgtgagg caggccgctg accgtgtgtt
     5641 tcacccagtc cgacagccac agcggtgaca ccgtgtgaag cggcaccagg agacgggcgt
     5701 cgaagccgac ggtgtaacgg gccctgggcc ggggggaggt cagcgccttc tcgatggtcc
     5761 gggcgaccgg ctcgggaccg gggacacgtg cgttgacagc cccgaacaga gacttcgacc
     5821 ggtcgtagcc cgccgctccg cctcggtcga cttgggcgag gtcgtcgatc gcccggtcca
     5881 gcatcgcggt ggcgaatgct ccaggctcca ccaaagacac gcggacaccg gcatgcgcca
     5941 tctccacgcg caggcagtgg gtgagcgcgc tcagcgcgtg cttgctcgcg ctgtaccagc
     6001 cgcccagcgg ccagggcact cgtcccaaac cagacgacac gttcacgatc cggccctcac
     6061 cacgtcgccg catctgcggc agggcgaggc ggcagatccg catcgccccc agaaggttca
     6121 cctccagcag gtaccgcgcc tgctcatcac tcacgtcctc aagcgacccg gcctgcggca
     6181 ccccggcgtt gttcaccacc gcccacaagc caccgcccgt catctccgcg atacgcccca
     6241 tcgcctcctc gcaggacgac ggctcggcga catccagtac caccgtcctc agcggccgcc
     6301 cgcgcgccgc ggcggcagcg agcaggccgt ccgccttctc ctggctgcgc gctgtaccga
     6361 tcacatcgaa accgcagccg gccaacctca gtgccgtcgc cgcgccgatt cccccagttg
     6421 cccccgtaac catcacactg cgttgaaccc gcaggccggt cgaggcatgc atctccattc
     6481 gtacgtcact ccccaggatc cacagacggc ccgcgccacc tggtacgcca ccgcacagtg
     6541 ggcaacgacc aggaagaaac gcagttgtgg cctcccgcag aatcactgcg agcctttgcc
     6601 cgcaggtcgg ggtcacgcct tggcgagcgc gaaccgcttc tggccggccg tcgggcgtac
     6661 gaccaggccg ggaggtctgc gcggcgccgc tactcggtcg gtgaagaccg tgggatcgca
     6721 gagcatgcct ggactgcgcc acgaggaggt gcgtccggtg gtcaccggcg ggcggtctcc
     6781 ggctggtcgg gcgcgacgtc gtcgccgtcg ccgccggcgg ggccgcagtc ccactccgcg
     6841 accacggtgc cggtctcccg gtagcgggcg atggcgtcct cgtccacggt gccgtcggcg
     6901 tcggtgaacc agatctccgg cagcggcccg tacgcctcct cgtaggcggc gacccaggcg
     6961 atcgggccgt ggccgttgtt cgcgacgtga cggatcggct ggccggcggt ctccaggcac
     7021 agggccgcgt aggccggggt gccgagcagt tcgtgccagg ccgcgtccac ggccggggag
     7081 aacatctccg gtgcggacag gccgctcttg aagcgctggc cggtgatggt caggaaccgg
     7141 cgcagctcgg tcgttgcggt actcacggtg gtgcccctct cggtgtcgag tggtgctcgc
     7201 cccggcccgg ggtgggacgg gtgtggtgcc gtgcaccgcg cacccgggag atccggtctc
     7261 tgccgggtgc gcggtgggtt tcaggggggc cgtgacggcc tggggtgcaa cgctggcgag
     7321 gcggtccagg cgctcgtaca gggcgcgtac gagccgggcg cggctctggg cgcagcgcgc
     7381 ggtgccctcc agcggaacgg acaggcggcg gtcggcttcc tcgaggacga cgtcggcgag
     7441 ggcgcgggcg gcgtggtctt cgggcagcag gtccgcggca cggcggacat cgacggcgac
     7501 ggcgcgggcg gtgccggtga gcagcagggc aatctgctgg aggtccgcag agggaaggct
     7561 ggggctcccg gtccatccga gcacggcctt gacgaggcac ttgtggagct cccggtcgag
     7621 ggggagctcg atgtcgaggc gtccttcggg gtcgtagagc acgacgtggg ggtcggtcat
     7681 cgtgcgccct ccgcgtcgtc gtcctggtcg tggtcgccgg tgtcggcggc cgggccatgg
     7741 atggcgagga agcgggcgta gccgcggtcg gcgcgggcca ggagcgccgg ggagggctgg
     7801 ccgaaggcgg gcggctggag tccgtggtct tccggctggg tgtcggcggg tgtgggtgcg
     7861 ctcatggggc accgcctccg tgtgctgggt gcgtcgcgtc ggtgtcgttc gacgctacgg
     7921 aggccgccgc gtggttctca acgagattgc gggtaattgc ggaacatcac tccagggcgt
     7981 cgatcgcggc ctggatgagg gcgcgggccg tgtcgccgta gacggccatc tcctggaggc
     8041 gggcgaacgc cttcgtgtag tcggcgactt cgcgtggctg ggtcaccttg atctccgctg
     8101 tcagggtctc caccacggcc gtggtgtcgt cgtggacgta gaacgcctcc agcggccaca
     8161 cggtgcgctg cgcggtgaac gggatgatcc cgagcgagac ggaggcgagc ggcatcacgg
     8221 ccaggaggtg gcgcagctgg ccgcgcatcg cctcggggtc ggcggttcgg tagcgcagga
     8281 cggattcctc gatgaggacg acgtagcggt ggccgccctc gtagaggaag cgggagcggg
     8341 cgatgcgggc ggcgacggct tcggtgacgt cgtcgggggt gccctggaag cgggtgatct
     8401 gcttcatgag ggcggtcgcg aacgccgggg tctggaggaa gccgggcggc acgttggaga
     8461 ggtagacgcg gcagtggcgg gtctgctcgt gcagggtgta ccagtcctgc tggacctgac
     8521 gcatgccgtt gcggtgcagg cggcgccact ccatgtacat ggagtcgacc gcgcgggcgg
     8581 tggcgatgag gtcggcggcc tggtcgtcgg cgccgcacgc cgtgcaccag gtccggatgt
     8641 ccgcgtccga ggggaggacc gcgccctttt ggatgcgggt ggtcttcgcg ggatgccagc
     8701 cgcaccgggc ggagagttcc ttcccggtga ggccggcgtc cttgcgcagg tgcgtgaggc
     8761 gcacggcgag cgcctcgcgg gccgcttgtg cgctggacga tggggaggcg ggcacaggtc
     8821 tgctcagggg gcctggacgg tgtacttctc gtgtgggatg ccgcgttccc agaccgcctc
     8881 gaacgccgtg gcgcacagcg cggccgcggc cggatcgtcg gtgcgttcct ttccgtccgg
     8941 cgcccagtcg ccggtgccgg tgaagtggtg gaactgcacg acgcgcccgt ccaggagcca
     9001 gaagtcgttg ccgggcagcg ggatgtcgct cgcctggcga cggggcagcc agcgcaggtc
     9061 ttccccggcc tggaggttga gcggggtgat ggcgtgctcg tagcggatgt agtcggtgac
     9121 cggctccgag acgatccgcg cgcggcgcat caccacgccg cgggcgaccg cgtccttgac
     9181 gagcggcatc cattgcggcc agaacgagcg ggccggatcg aggttcggga ccaggaagga
     9241 ctcgaagtcg tcccgttcgt cgcccaccgc gtagacgacg cgcatctcca ggtggacggc
     9301 cgtgcggtgg gtgtgaggaa gcccagcccc gagtcgcgca tgagctgggc atcgctgctg
     9361 atgaactggc tggtctgcac cggcggttcg aggtcatccc cggtgctcaa gcccaggtcg
     9421 actggggtga cgagggcaag gtcctcgctc acgtcggcct cccgaaggtc tactcgttcc
     9481 acatggtctt gtcctactcg cgcgatccgt tctgctgttt caccaccagc caggacctgg
     9541 cgacgttctt cgactgccac cgccaagcgt tcacgcattt cggtggggtg ccgatgacga
     9601 tcgtctatga ccgcaccaag acggttgtcg gcgtacacgt gaactttaag gagtacgccg
     9661 acaacgtggt tgcgcatagt tgcgcgcacc gaccgtccag cagcacagag agccggtcaa
     9721 gaggaccgag aaggctggag gggctggccc acgcggcgcg gtgcgggcca gcctccgcca
     9781 gtttctgccg gcgggacgtg cggccagcgc tgcgcgcagg cgcgcggcaa tgggctgcta
     9841 ccgctggacg aagctggggt ccttcatctg gtcgggctcg gacagctgct tgtgcggggc
     9901 aggccggcgc ccggcgagcg accagcccag gggcgcagtc cggcgcggcg ccggtccggg
     9961 tcgtcgacgc ctccctcgta ccagggctcg ccgcgctggt tcattgccgc gtggtgggaa
    10021 gtagttggtg atcggtacgg tccgagtgca gggtcacggt cccccgggcg atggggcggt
    10081 cgatgaagtc cgcagtgccg tggtatcggg gtgcgaagcg ggcttgctcg aggtttcccg
    10141 agatcacgta ctccaggttg tggagatagg ccgcaacggc gcagtcagcg cccagccgcg
    10201 aactgcggag cgtagtcagc atgtcagcga tctgttgttc cttgagggcc acgaggttta
    10261 cgagcttgtc gattgcctgc tggagagttg cgccagctgt gagtagcacg cagaccgcgt
    10321 tgacgtggtc accggcgaag tgctcggcgc ggaaggagaa caggtcgttg gagaacagca
    10381 ggtgttcggc acaggcccag tgcagggaac gtagcctggc cagcaccggg tcggtgagat
    10441 ctacgcctgc cgcgtactcg gtgaggatga agtagaccca cgcggccagg ctctgctcga
    10501 ggcgcacgct ggtgtagctg gcaaggtcca ggactgagcc ctgtgcgcgt gaggacacct
    10561 cgcgcaggca tccgcgggcg aagcctcgtg cggcttcggt cagcctgtga cgttgccggg
    10621 cgggcatccg ctgtgccatc gcctgccaga catcggccaa cgccctgcca tgggccgtag
    10681 ccggtgctcc tccttgcatc acgtgcagcg tgtcgttgag gacctgttcg acgtcggtgg
    10741 agctgtcggg gctgctctgg aggaacaggt cgtcgaaggc gaagaggaat gaggtgaggc
    10801 gagcgaggtc gtggaatcgg tcttcgtcgg tgaccgggta ggtgaacgct gtccacaatg
    10861 cgctgcgctg ggcgaggaag gtgtcccggg cgcggtcagt ggggaagggg tagtgctcgg
    10921 tcagccacag gtcgtgccat cgttcgagct tggtgatggc cgggtgacgc tggcgggcca
    10981 gccggagggg aatggcggcg agctcgtaga cggcgccagt gtcgatggtg tgggtcatgg
    11041 cagcaagccc atgccctccc gcttcgggct ttcgacccat ccgtcatcgg agtaccggtt
    11101 ggccccgaac agctgatacc aggtggtgac gccgctggtc gcgagcgcca tgtggtgtac
    11161 gacgcgttcc acgtccggct gatcggcgcc gaagtccgga agtgcgtcgg cgagggcgac
    11221 gaactcggcg aggtcggcgt catggatgcg aagcatctca tcgcaggctt gttcaaggga
    11281 caggtcgtcc tcgcgttgga ggacgaatgc caggttgatc gtctccccgt cgccactgcg
    11341 ggggatttcc ttcggcatcg agtaggcgtc gttctgccag gcggtgatgc gcgccaggag
    11401 atgcatggct cttcggatgg ccggatgcgt cgcgatgtgg tcgggcagcg gtacccccag
    11461 ttcgagttcc accagtgtca gccaggggta catgccgacg ctgtagggcc ggaactcctc
    11521 cagttcggca agagacggga cgcgctggtc cagcttgaag ggtgcctccg cctcgatccc
    11581 tttttgaatg aagttctcgt ggttctcacg ggagaaccgg ctcagccagt gcggcggcat
    11641 cagctctgtg gccatgaccc gcaggtcggc agccatcctc agcaccggat gctcgtcggt
    11701 gcgggggcgg gcaccatcca ggatttcgcc gacccgtcgg cgcagggctg cgagttcagc
    11761 aggggagctc gtcccgaagt ggtcgtcgag gtgcgttgcc cagagtgaga acagagcagt
    11821 ggtcaacgct ctctcgtgcg agagcgagtg agggaaggag tacgcggtga caaggtccag
    11881 tctctgtcgc cggtaacggg ctcggccttc ctcgggcagg tggatgaact gatcgcacca
    11941 cgtgtcgtat tgcggcgcca tggactgggc ataggggctg tgcgcggtga agcggtcggg
    12001 gagccggaat ctgcgcggcc tgacaatctc ggccagggag tccatggacg gcaaggtgga
    12061 tctccgctct cgacagagcc gctcatgcga ctctggtggt ggtgtcgtag gcgatctgac
    12121 gcagcgcgtc agtggcggca agggggaatg ggcccgtgtc cagtgagcgg agcgcccgct
    12181 cacgccgcga ggtgatcatg tgctcgacgc tgtcgcgggc gccggtcgcg atgaggatgt
    12241 cccggatgcg ggcagcgccg ccctcgtcca gcccgggatc gccgacaagc ttttcgagag
    12301 cctgccgctg gactgggtcg gcgcgttgca gggcgtgggc cagcaggacc gtgtgctttc
    12361 cgtcgcgcag gtcctccata caggatttgc ccgtcgtatc gagcgttccg aagacgccga
    12421 ggaggtcgtc tcggagttgg aacgcctcac cgagaggcag ggcgaaggcg ctcagcgcgg
    12481 agcgcgtgtc ggcggctgtg ccagcgaggg cggcaccgat gtgcaggggc cgctcgacgg
    12541 tgtacttggc ggtcttgtag cgcacgatct ccatggcccg ctcaatgtcg ctggtgggcc
    12601 ggcctgcggc gacaacatca aggtactggc cgtacatgag ctcggtgcgc atgttttcga
    12661 cgaccggtag ggcggcggcc agttgggcgg gagtgaggca tgtcgtggga aagagctcgt
    12721 ctgaccaggc aagggcgagg tcaccgatga ggatggccgt gctgatgccc aggtgctcgg
    12781 cctgtgcttg agagcgagcg ccgcggtgga ggtcagcgag gacacggtga agagtgggcc
    12841 ggccgcggcg tgtggcggaa cggtcaacca cgtcgtcatg gatcagtgcg aaggtgtgga
    12901 acatctccag cgacgcggcc gcgtgaagta ccggggtgat gtcttcctgt ccgctagcgg
    12961 cgtaccagcc cagtacgcac agcaagggcc gcaggcgctt gccgccggag aacagcaagg
    13021 catgcaacgc ttcgccagtt tcacggggca ggtggcaggc ggattctgtg cggcgctttt
    13081 ctgccaggaa ggtgtccagc acagtatcga cggcatgacg cacgccccgc aggtccagca
    13141 gggtcacatc cactgccgca ggcgccggca ttgggcattg ccgctggctg ccagggacgg
    13201 cggcaggagc aaagtcggca ttctcgctca tcccgccccg cagagtgatc acttcatagc
    13261 ccgtcaagac tacagagagt gcgactgaaa tcactagacg tagtttcagt cagtgtggcc
    13321 gaaacgcgac ttaccgtgaa ggcgtgccca cacgctccga caacgcagcc gagccggcgc
    13381 ccgaccggaa ccagccgccg cgcgcaccga ccgtcccgca gcgcagagag ccggtcaaga
    13441 ggaccgagag gctggagggc tggccccacg ggatgcggtg cgggccagcc tcccaggtca
    13501 gttcctgccg gcgggacgtg cggccagtgc tgttcgcagg cgtgcggcga tgggctggaa
    13561 tcgctggacg aagctggggt ccttcatctg gtcgggctcg gacagctgct tgtgcgaggc
    13621 gggccggcga tcgcccgaca cctggggcac gaccgcaaga caatccgcgc gtatctgaac
    13681 ggcgagcgag tctccggcta tcgccgccag tcgccagacg cgttcatgcc cttcctggag
    13741 tattgccgcc aacggctcag cgacgaccct cacttgtggg cctcgacgct cttcgatgaa
    13801 gtcgtagaac tcggctatac aggcggatac tccaccttca cgcgagccct gcgacgatac
    13861 aaagcgcgtc cgcactgcga accctgtcgg gcttcgaacg gccgcgacgt ggcgatcatc
    13921 gcgcatcctc cgggtgagga gatccagttc gactgggtcg agctcccgga cccgcccgtg
    13981 gagtggggcg tcggtgccaa cgcgcatctc ctcgtcggcg ccctggctca ctcgggacga
    14041 tggcgggctg tgctggcgga ggcggagacc ttcccgcacc tggttcaggc catcgacgcc
    14101 gtgctgcggc gcctgggcgg aacggcccgg aggtggcggt tcgaccggat ggccaccgtc
    14161 tgccacccgc cgaccggacg gatcctgcca accttcgcct ccgtcgcaaa gtactacgga
    14221 gccggcgtcg acatctgccc gccccggcgg ggcaaccgca agggtgtcgt cgagaaggcc
    14281 aaccactcag cagcccaacg atggtggcga actgtcccgg acggcatcag catcggggca
    14341 ggtcagaacg gcgtcgacaa gctggccgtg cagatggaca gccgcaaacg caaactcgac
    14401 ggagcctcga ccacggtcgc cgcgctcgct gaggccgagc cgctgctgga cctcccaccc
    14461 cgtccgttcc ccgctgagct ggagcagatc cgtgtcgtca gcccgcaagg gcttgtcttc
    14521 ttcgcaggca accactactc cgtcccgccc gggctggtcg gcgcccacgt cacggtccgg
    14581 atccgcctcg gcgaggacga cttgcatgtg gtcaccgcca gccgcgcggt catcgcacac
    14641 caccgccggg caccggatgg cgcggggcag accgttcggg actccgggca cgtcgttgcc
    14701 ctcgaacgag ccgttctcgc ctcgttctcc gacaaggctc cctgccgcac caaggtccgt
    14761 cggcccccgt cggctgcggc ccaggcggaa gccgagaagc ttcgcggtcg gcctgaatcg
    14821 gacgtcgcga accgggtcgt gatcgacctg tctcactacg ccgccgtcgc cgaccggctg
    14881 cggcaggccc ccacccacga agaccaggag tgtgagagtg agtgacgcca tgccgatgag
    14941 cgaggcccgc cgctaccagc agttgcgggg ccacctgtcc tatctgaagc tcaatgacgc
    15001 cgccgaagcc cttccccgcg tcctagacca ggcccgcgcc gagcggatga ccctcaccac
    15061 ggcgctggag aaactccttg agatcgaggt cgaggcgacg gaagcacgca aactctcctc
    15121 ccggctcagg ttcgcctgcc tgccggaacc ctggaccctg aacgacttcg actttgctgc
    15181 ccagcccggc gtcgaagaga actcatccgc gacctggcca ctctgcggtt cctcgataac
    15241 gcctccaacg tcctgctggt cggcccgccc ggcgtcggca agacgatgct ggccgtcgca
    15301 ctcgctcgct ccgcggtcga cgctggccac cgcgtctact tcaccaccgc cgccgaactc
    15361 gccgccaagt gtcacaaggc cgccctcgaa ggccgctggt cgagcatcat gaggttcttc
    15421 gccggagccc ccggctactc gtgatcgatg aactgggcta tctcccgcta cccggcgacg
    15481 gcgcctcggc cctcttccag gtgatcaacc agagatatct gaagtcgagc acgatcctca
    15541 cgaccaatgt cggtattgcc gactgggccg gcgccttcgg cgacgcgacc gtcgccgccg
    15601 cgatgctcga ccggctcctg caccgtgctg ccgtggtcgg catcgacgga ccgtcctacc
    15661 ggctccgctc tcaccagtcc cacgccgaca acctccgcaa aggagtgacc ggacgtgctg
    15721 gttgaattcc gggagtgccc catctgctgg acgtcattcc aggtcaaccg caatgcagcg
    15781 gcccggcaca cctactgcac ccctcgctgc aaagcagagg ccgctcggcg ccgacgccgc
    15841 gaacgcgacg aagccgccga cgtcgctgaa ggcgaaccga tgacgtcagc gtcgccagac
    15901 ccgacaccac tcgcgccgac ggccgtccgg aactgcccac actgcgacaa gcccgtcacc
    15961 atcgtcgccc tgctggccac tcccgaagcc gcacgaccca ccatcccagc agcaagtcgg
    16021 gacgtgatcc cgatgcgcag aagctgacac cgtccgacgg gaatcggcag gacacgatca
    16081 gtcgccattc actactgtca catcggaaag gatgtggaca tggcactggt caaaaaggga
    16141 tcgcggctca tcaccgtgga cggcatgacc taccggtggc gactccgcgg acggccgacc
    16201 tacgaccagg gcctggtccg gtcacccctc acctacgcgg tcgaacacgc cgacgcttcc
    16261 ggaaccacac tggtggtcac caccaacaag ccgcacccga gcaactggtt cggaacacaa
    16321 ggcagcccga ttctgcctgg ccaggtggct gacagcatcc gcaccgcgct cagcgatggc
    16381 tggacgcccg aaggccccgg ctcaccattc cacctcgacc agtcagcggg cttcgtctcg
    16441 ccccactgac tcaccacacg ctcaaggact caccggggcc agcgatcggt gagtccttct
    16501 gctttctgct ccccacttcc ccagttggtt cacttcgtga accaactggg gcgaagagca
    16561 gccgtgggga aaattcgaga tcggcatcag ctcacggtag taacggcagg gaccgtgctg
    16621 gccacgacat caacagcgtc tgctggaggg atcggcgact ccctgtcccc ggccttcgac
    16681 accagttgca ccaaccacca cggcatccac gcagacggtg cgaccaccca cggcactggg
    16741 gcggccaacg gcaactccgc cgggcttccc atcggtaacc ccatcaacca atgtggcggc
    16801 gccgacgtgc cgagggttga ggtcttggac gggaaactgc tcgacttgag ccttcccgga
    16861 cactgatcac ccatccgggg tgcgggccgg cggtgttccc gacgcgaggg ccggaggctc
    16921 agggtctgag tgagaacctc ggaagccaag gtcagagcct tcggccgaat ttcagagcac
    16981 tgccgaacgg tcagccgcag gcgactgggt agaactcccc gagcggtccg agccgacgcc
    17041 catcgccccg ggcgccggcc tccttccggg gcggctacag gacgcggacg tccgtcgcct
    17101 gcgggccttt ctggccctgg gcgacctcgt actcgacccg ctggccttcg tacaggctcg
    17161 tgaagccact gcccccgagc gcggagtagt ggacgaacac gtcagggccg cccccgtccg
    17221 gcgcaatgaa cccaaagccc ttctctgcgt tgaaccacct cacagtgccg gtatccgccg
    17281 ggacgcgctc ggtatggccg accggtgccg ccgtgtgggc ggacgcttcg gcgagagggg
    17341 ctacaaagag ggcagcagcc gcggccacga atacagcaag gcgtgcaggg cgcacagtgg
    17401 gaacctttcg gcaggccaca agacccggta gctgcctacc tggtcccgcg gagtgggagg
    17461 tcccaagcct tgtccccaca tgactgccac acctaccgca gcaccccgac cctcactcgc
    17521 acgcaccaca acccccggcg gatacgcccc gcgcattgcg cagaccgccc gctccgccgg
    17581 ccgctcccga cacctgcacg ctcacggacc gccggtagcc cttcggacag gtgagacgtg
    17641 atcactcgcg ccgtggcaga acaagtcccc tgaaccgctc cacaccacga cgtcctgcgg
    17701 gccgctgtgc agcgcgccat ccgatagcac cccgctgggg ctggcatcca tttagcaaac
    17761 taggttgttg ctcttcccag tgtcgctctc ctggttcagg atctccttga gctggaccaa
    17821 ctgggcgtca ctcttcccgt tttcgtgcgc gcagttcttc gcgttaaacg aatcgtgtag
    17881 cgggagatcg gcgcctccgc actggttgag gggcccggta gtgggcaacg tgagcaggtt
    17941 gcctgctccg tggccggtcg cggccgtcgt gccgccctgc gctgctgcgc cgaccctctg
    18001 gttggcgcag ccattgccga tcgcgggcga gaggaagtct ccgattcctc cggcccaggc
    18061 tggggcggcg ccctggccga ccccagcaaa ggtgagcgtg acagcgatcg cgcaggcgaa
    18121 tgtgcgtagt ttcatgccct gacaacgatg ctgatcgcga atcagcacta tctagggccg
    18181 caagagagac aagggccgtt gcatcgcttc cacccttgag tttgccccgg tgtgccgtga
    18241 cccacggtgc caagtagccg cctctcctgt tgggttctgg tgcatttcac tcgttttgac
    18301 ggcggtggcg cccgaaagat gtgggctggg aatcgttgcc gtccacgtaa gggtgaccca
    18361 ggacattact actcggcggt acgggaacac atggtccgat tcatccggcc ccatgtgaaa
    18421 ggactcccta tgcgccgtgc cgcagctgtc atcctcacag ccggagcact cctgacgacc
    18481 ctcacaacca ccacggcagc cgccaacccc gccgacccct ggccccctat ccaactcccc
    18541 gagatccagc tccccaccct ccccgagatg cccgaaatcc ccggcgtgcc cgagcccgaa
    18601 tcttcctaac ggggcgcggc cggggatgac gagcggcgtg ggatggtgac ctgcggctcc
    18661 gccaggacga cgcgggtcgc cggctcgcgg tgcacgggaa cgcggacgct gttgcactcc
    18721 cgtgtgcagg gcggtgttgc acgaggcgct gtgagccacc gtgcgatcgg gcccaggctg
    18781 gctaccagcg gcgcaagtct ttggtgagtt cgaggtacca ctcggtgcgg cgcggcacgt
    18841 actcgtcagg ggccggttcg agcgcgacga cctggtctgt gatcccgtag gtgactcggt
    18901 aggccaggac ctgggtggcg aggtccatcc actcctgcgt cttgtgcgcc ggcggcacgg
    18961 gaccgagcac ggtcacgaac cacatgggca gcagggcgcg gtcgcggatc gcctcggcca
    19021 gacggctgcg cagcagccag ttcagcttcc tttccgcttt gtcgccctgc tcgatcagcg
    19081 acgccttcgc ctgcctcaga gagtcgtcct gagccagtgc ggcctgggcg gtctgggcgg
    19141 ggccagccag tttacgggcc cgctgatcgt gtctctcggc gagggtgtgg gacatgccga
    19201 agtccatgac ggcctgcttg aactcgcggg acgtgcgcgg ctgagtggcc aggatgccgg
    19261 cggcctccac caccttgtcg cggtgctcgt cgcgttcggc gatcgcgcct tcgtactcgc
    19321 ggaccttgat gcggtgggct tcgcgctggt gtctggggag caggccggag cgtacgtgcc
    19381 agccgtggtt ggcggtcctg gccagcttca tccactccgg gtcgatggtg tcgaggtcgg
    19441 cgagtggggc gccgcccgcg gccagtaggt gggcttcgag ggcctggacg cggccggtca
    19501 gccgcttgag ggattggtcc gtgccctgga tgtggccgcg tacgtcgtcg tccagctcgg
    19561 tgaggtcgtt gcggacggtg ctgaggtcgt cctcgagact gcggatgtcg ccgcggatgt
    19621 cgcgcaactc gtagtcgagg tcttcgacct cccccagctt cgaacgcagc gagtgcagct
    19681 cgtgctccat cccgccggtc cgggtctcca ggcggcggac ctggtagccg tagtcgtcgc
    19741 tcaccgccgc gcccccttcg cgtccgtgct gtccatggag gacccagcga caagcatcca
    19801 gcccacggcg gcggcgatga tgaaccaccg gctgatcacg ctcaggctaa tgagggccat
    19861 caggagcgcg accacgtgca gtgcgacggc tccgaagcgg cggtcacggt gctgttcggc
    19921 atcgaccttc tggaagcagc cggccacagt tcccacgaag tgcgggacca gcaggaccag
    19981 ccaccaggtc gagtggtcaa ggacgaagac gagcgcgatc agcaccgctc cgacggccgc
    20041 ctggccgcgc caggaccacg tcacgatgcg ctcactgcgc ctgcgatcgg gttcggccag
    20101 acgctcgggg atcgtcttct cgaactccac cagcttgctg gtgacgttca ccagccgggc
    20161 gtactccacc gcgaactggt caccgtcgga gtgcttcagc acctccgcat ggcgagcacc
    20221 gaccttctgc tgaagctgcg cgaactgctc ctcggtcttc tgctcggtgc tgcccaccga
    20281 accaccccca cccgcaatgc gacgacacgc cgaccggaca cttcccaccg gcggccaccg
    20341 ccagccgtga aactgatcga ccgtacccac agctgtccgg tacccgccgg gcaatcagat
    20401 gcagtggccg aaccatgccg atcaaccccg tgcatcgaag ccgaggcccg tggtcgcctg
    20461 ggtgcagttc agacggtccg catggcaggc agggtcttag cgaagtagag cgccgtgttt
    20521 cgtacacctc ggttcgagat cacctaggcc gtcgacctgg ccgacggcgg cgcggccctg
    20581 ctgatcgccg tgctcataaa ccatggtcag cacgtgcttt acatcctcgg ccgcatggtc
    20641 aaccgagcct ccggcagcta tcgcggcgag ggcaagaccg atgcccgcga cgcgcttgtc
    20701 atcgctgacg attacatagg ggctggcact cgccacgcgg gcgctgtccc tgatctgggt
    20761 gtgttgccgg gcggggtggc attcgggacg gagctcgacg gctgctgggt actcctgttc
    20821 actgcgcctg gccgggcggc cccgcgctgt tggactgccg cgcctttgta cgtggcgtcc
    20881 agcggcgcca ggaggtgccc atttcggccg cccgtcggcg cgcggcggtg agccctcctc
    20941 ccacgcaacg tcgaagtggc tctacaccct gcccaggttc tcgatggtcc ttgtgcatgt
    21001 ccccgcgggc gcagaaccgg cgagcgtggg cggtccactg cccagcgggc atctccagtt
    21061 ggctccgcga agcgtattac cgtgggcttg aaggctgcgc atacgccgta tagggcctga
    21121 gtcgggccgc tgtgatcggt gtccggtcag ccgccggacg gagtgacagg gaataccgag
    21181 catgtggcgg tcggtcgaat tccggtacga ctaacggctg ctcagtgcgt ggcgtgactt
    21241 gattgttccc tctgatcagc acgatgaggc cgacggcccc gaccggctcg gccgttgtca
    21301 agttcggcgg acccgccagg accggtgcgt tcgtggtgat gagtgcggag ggcgcaatgg
    21361 tggtcagtcg tcgaagggtg ctgtggggcg gagcgcaggc gttggccctg gccagtgcgg
    21421 gccggatgac tgcgggtgtc gcgcaggccg tgcccgtgcg gcacacgcca acctgggaag
    21481 gcagcctgcc ggcctcgtcg tggcgcagcc tcgaacgggc gctgagcctc ggtgccgggc
    21541 tctaccggcc cgggaacgcc aattaccaga agctggtgct gccggacaac cggcgctatg
    21601 cggcggtgcg gccggcgggc atcaccgcgt gcgccacgga gaaggacgtg cgggcggctc
    21661 tggggtgggc cgccgaccac gggatgccgt tcgccgtgcg ctcgggcggt cacaattacg
    21721 ccggttactc caccacgaca ggactgctga tcagcctgcg ccgcatgcgc ggtgtggtcc
    21781 ccagcggtca ccggctcgtg ctgggcggag gcgccaccaa ctccgacgtc tacgaggcga
    21841 aagcggcgaa cctgtacttc cccggcggcc gttgccccgg cgtgggcgtc gccgggctca
    21901 ccctgggcgg gggcttgggc ttcaacgacc gcaagtgggg cctaacgtgt gaccggctgg
    21961 tggagacacg cctggtactg gccgacggct ccctggtacg ggccagcgcg cgggagaacg
    22021 cggatctgtt ctgggcgtgc cgaggcggag ccggcggcaa cttcggcatc aacaccggtt
    22081 tcaccttcga ggccgtcgac gtctccgccc agcgcgccac cgtcttcgac ctgacctttc
    22141 ccgtccgaca gggcgtcgag gtcatggccg ccgtccaaga agccctggcc gcggacgagc
    22201 acaacgccct ggacgtgcgc atcggcttca agaacgaggg gcagggcaac ggcgggacgc
    22261 tgtggctcct gggccagcgc ctgggcggcc aggacagcct tcagcgggca ctcgcacccg
    22321 tactgtccct gcgcccgaag aaggcattcg tgcaggagcg gcacttctgg gacgcccagg
    22381 actacctcat ggaacgccct ggcacgccgg cggccagtgc ctccaagtcg ctcgtaccgg
    22441 acagccacat cggccgaccc gctgtcgagg acatcatcgg ctggatcgag gactggcaac
    22501 ccggccagag gggcaacgcc ggctacgtga cactgttcgc catgggcggc tccagcgccc
    22561 agccggggaa cggcgaaacc gcatacccgc accggcgggg aacgttcgtc atcgacatcg
    22621 gcagccactg gcacaccgac actccccgcc agaccgtcga cggcctgctc gctcagctgc
    22681 ggacgatgca ccgcaccctg cgacgcggcc tcgagacctc cgccgcgtac gtcaacttcc
    22741 ccgacccgga cctgcacgac tggcagcacg cctactacgg cgcgaactac gaacgtctga
    22801 ccgacgtcaa gcatcactac gacccgaccg ggcttttccg ctacggccag agcatcggcg
    22861 tcgctgatac cgcgacggcg cacccctgac cagaagttct ttgaccgacg gggcagtgtc
    22921 caggacgccg ccagcgcggc aagcaatccg gtgctgttgt ccggcgcgca gggcgggggc
    22981 ggcttcgatg tcgatctctc ccgcagacgg cgatcagagc gaggccatgg tcggtgtgct
    23041 ggacggggag gtcagatcgt cagtcacgag aggggctcct ggccggtgcc gggccggcgg
    23101 tgaagagccc tcagcatcga tcggcccggc cgctcacgaa tcgtggtgct cctggggccg
    23161 cagccgtgta agtaagcccg gagggatgag cacgcagagg ggggacatgg gatcggggtg
    23221 ttgcggtgag t
//
