LOCUS       NZ_AUBE01000014        11341 bp    DNA     linear   CON 22-APR-2024
DEFINITION  Streptomyces flavidovirens DSM 40150 G412DRAFT_scaffold00013.13_C,
            whole genome shotgun sequence.
ACCESSION   NZ_AUBE01000014
VERSION     NZ_AUBE01000014.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces flavidovirens DSM 40150
  ORGANISM  Streptomyces flavidovirens DSM 40150
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 206994)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUL-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            environment                       :: Soil
            investigation_type                :: bacteria_archaea
            project_name :: Streptomyces flavidovirens DSM 40150
            sequencing_meth                   :: WGS
            ref_biomaterial                   :: DSM 40150, ATCC 19900
            finishing_strategy                :: Level 1: Standard Draft
            GOLD Stamp ID                     :: Gi11969
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2012
            Isolation Site                    :: Soil
            Sporulation                       :: Sporulating
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Unknown program v. before 2013-03-07
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000429085.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 01:37:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,525
            CDSs (total)                      :: 6,452
            Genes (coding)                    :: 6,216
            CDSs (with protein)               :: 6,216
            Genes (RNA)                       :: 73
            rRNAs                             :: 6, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 236
            CDSs (without protein)            :: 236
            Pseudo Genes (ambiguous residues) :: 0 of 236
            Pseudo Genes (frameshifted)       :: 106 of 236
            Pseudo Genes (incomplete)         :: 173 of 236
            Pseudo Genes (internal stop)      :: 25 of 236
            Pseudo Genes (multiple problems)  :: 59 of 236
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:04:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 154689
            Orig. end                         :: 166030
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AUBE01000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..11341
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11341
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11341
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6341](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6341)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            468..1199
                     /gene="hemQ"
                     /locus_tag="G412_RS0120370"
     CDS             468..1199
                     /EC_number="1.3.98.5"
                     /codon_start=1
                     /gene="hemQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037014.1"
                     /locus_tag="G412_RS0120370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydrogen peroxide-dependent heme synthase"
                     /protein_id="WP_028813694.1"
                     /transl_table=11
                     /translation="MTDAPETVTSPRGPNAGKKAKDLNDVIRYTLWSVFKLRDVLPEDR
                     AGYADEVQELFDQLAAKDVTVRGTYDVSGLRADADVMIWWHAETADQLQEAYNLFRRTR
                     LGRALEPVWSNMALHRPAEFNKSHIPAFLADEMPRNYVSVYPFVRSYDWYLLPDEDRRR
                     MLADHGKMARGFPDVRANTVASFSLGDYEWLLAFEADELYRIVDLMRHLRASEARMHVR
                     EEVPFYTGRRKSVADLVAGLA"
     gene            complement(1324..2928)
                     /locus_tag="G412_RS0120375"
     CDS             complement(1324..2928)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (104-478). E-value:
                     1.7e-19. Score: 62.3. Matches aSDomain:
                     nrpspksdomains_G412_RS0120375_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890184.1"
                     /locus_tag="G412_RS0120375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_028813695.1"
                     /sec_met_domain="PF00561 (E-value: 5.2e-25, bitscore: 82.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALAMYGTLASVGSLVLTALVAAPAGSAESAASPEARGTALAAH
                     RAAAAGIAFGACPASEGLPKHVRCGTVKVPLDYADPGGRQISLTVSRARATGKPAARQG
                     ALVYNPGGPGASSMFFPMAGVLPEWKRIGAAYDLVGYAPRGVGRSAPLSCQKPSELVQA
                     PSHAPAHPSSAYKEERKARAKAYADGCARTAGSALRHYTSLNNARDLDVLRAALGERKL
                     TFMGASYGTYFGALYATLFPSHVRRMVFDSAVNPAPGQIWYRNNLDQSLAFEGRWKDFR
                     TWVAKHDRTYHLGATPEAVLASYEKVRAGLSRKPAGGRVGTAQLQSALLSAGYYDDYWA
                     MRATALSEYLKGNPKPLIEQASPRPESAKDDENSKAVYTAVECNDAPWPTEWWVWDRDN
                     SLLAERAPFETWANAWMNLPCAYWSAPRQEPLDVGTRPGELPPTLILAAERDAATPYPG
                     ALELQRRLAGSALVTERDAGTHGIGGGANKCVNGHLETYLLTGRTPVRRAQCAPHREPN
                     PVSLDKRAVAKKPAPTV"
     aSDomain        complement(1495..2616)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G412_RS0120375_Abhydrolase_1.1"
                     /evalue="1.70E-19"
                     /label="G412_RS0120375_Abhydrolase_1.1"
                     /locus_tag="G412_RS0120375"
                     /protein_end="478"
                     /protein_start="104"
                     /score="62.3"
                     /tool="antismash"
                     /translation="ALVYNPGGPGASSMFFPMAGVLPEWKRIGAAYDLVGYAPRGVGRS
                     APLSCQKPSELVQAPSHAPAHPSSAYKEERKARAKAYADGCARTAGSALRHYTSLNNAR
                     DLDVLRAALGERKLTFMGASYGTYFGALYATLFPSHVRRMVFDSAVNPAPGQIWYRNNL
                     DQSLAFEGRWKDFRTWVAKHDRTYHLGATPEAVLASYEKVRAGLSRKPAGGRVGTAQLQ
                     SALLSAGYYDDYWAMRATALSEYLKGNPKPLIEQASPRPESAKDDENSKAVYTAVECND
                     APWPTEWWVWDRDNSLLAERAPFETWANAWMNLPCAYWSAPRQEPLDVGTRPGELPPTL
                     ILAAERDAATPYPGALELQRRLAGSALVTERDAG"
     gene            complement(3015..3809)
                     /locus_tag="G412_RS0120380"
     CDS             complement(3015..3809)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432059.1"
                     /locus_tag="G412_RS0120380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_028813696.1"
                     /transl_table=11
                     /translation="MFWVLFLIVACVAAAVSCARLCLAASVAAGHPERPVDAARPAPAP
                     QDYELSLYETAFLAGGPVRVADLALVSMHRRRRLLLAHTGWATVVVDPRGEDDVERSVL
                     GAIGPAGQSPVAAIRTATTTADAVRAVADRLVSAGLAVPDAVRAPLTSAVRSVRAATLL
                     VLALAAASLLLPGQEQAAGRGLVAAWFALPLGLSLGCLAIARFEIHTYTGWASPAGRRV
                     LDALAPGHRTGERAFLTAVARLGVRAVDDPHLRAALAARRGH"
     misc_feature    3900..3915
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.17"
                     /tool="antismash"
     gene            complement(3959..4993)
                     /locus_tag="G412_RS0120385"
     CDS             complement(3959..4993)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612179.1"
                     /locus_tag="G412_RS0120385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_028813697.1"
                     /transl_table=11
                     /translation="MTTTVLALLIALAIVAVSIILFRGTSALRRGPAGTGPVPLHDLME
                     VAFLNGGPSRVVDTALATMHSDGRLAIGGPGIVSARSTVAHGPVERSVYAELAAAPNGA
                     LHNLRYAVMRGEAVQEIGDSLAFRGLMVPPQAGRKWRTGSIVLLITCILGLPACIVTAI
                     AVSVAGHSAVPFITLVLPALVWGIVCGAVNAGRAAARVTPAGRAAAAAYAASHADRTAS
                     GHLVAVRGLRALPDRALWEQLHTAARLTPGGSRTTSRTTSRTPSTDSGTSTTYAAAAMV
                     WCAGSASGASSCGSSSGDSGSRSGGSGCSSSSGGSSCGSGSGSSCGSSSGSSCSSGSSC
                     GSSS"
     gene            complement(5001..6341)
                     /locus_tag="G412_RS0120390"
     CDS             complement(5001..6341)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888544.1"
                     /locus_tag="G412_RS0120390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_028813698.1"
                     /sec_met_domain="DUF692 (E-value: 2.7e-94, bitscore: 308.9,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERLGRLGTGIGWRPEIADAVEGLPGIDWVEAVAENLCPGHLPDS
                     ILRLRARGTKVIPHGVSLGLGGADRPDAARLADLAATAEALGAPLVTEHIAFVRAGGPL
                     TASPLLEAGHLLPVPRTRDALDVLCENVRIAQDSLPVPLALENIAALINWPDEDMTEGQ
                     FLAELVSRTGVRLLIDVANLHTNHVNRGEDPSAALDELPVEAIAYVHVAGGIEKDGVWH
                     DTHAHPVSRPVLDILTDLRSRTDPPGVLLERDDNFPPTEDLARELTRIRTALTPPAQRA
                     ERPQATPPAAPERGEDPVVGVPAGARRGDDARIRVALAQAALLSALVAGTPVPAGFDSA
                     RLRVQSRALAGKRADVVAKVAPELPQLLGAAAYRDAFLAYAKSRPMSAGYRRDALDFAE
                     HLLATGRPGDEAARRQLTVWWQDRAGPRPPRRTTRFVRAARAALVRK"
     gene            complement(6432..7217)
                     /locus_tag="G412_RS0120395"
     CDS             complement(6432..7217)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006345814.1"
                     /locus_tag="G412_RS0120395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4142 domain-containing protein"
                     /protein_id="WP_208857912.1"
                     /transl_table=11
                     /translation="MRRINGTALIIAALVATIGALAFPVWSYADRSGTGQANLNASTVA
                     TQWGPLSATDRDFLVKVRLAGLWELPAGQQAIERAPSEAIKEAGDHLVVGHADLDKRAR
                     SVAAQLNVPLPNQPNEQQQGWLRELSAASGPEYERKFANLLRNAHGKVFSLVAQVRHTT
                     RNALIRQLATDANQTVLDHITMLEATGLVDFDALANEAAGNTTASPTGPPPPDGSVTVP
                     SPPAAVPTGDQTFTSRPSAQPEGEIGSPAVNTNRPEPSP"
     gene            complement(7353..8159)
                     /locus_tag="G412_RS0120400"
     CDS             complement(7353..8159)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060126.1"
                     /locus_tag="G412_RS0120400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_341860597.1"
                     /transl_table=11
                     /translation="MRRREGTPLRIALNQMLSDSDPRRNLEIIEAGIAEAAGHQADLVV
                     FPEAAMARFGTPLAAVAEPLKGPWAEAVRAMSARAGLTVVVGMFTPGDGGRVRNTLLIT
                     GPGVDTHYDKIHLFDALGYTESETVAPGRQPVTFQLNGLTFGVATCYDVRFPSLFHELA
                     ARGAQAILLPASWADGPGKADQWDVLVRARALDSGAWVLACDQASPRSIGRDPGTEPLG
                     IGRSMAVSPSGEVRHQLDAAPGLLIVDLHTTELSASPRCVAGRRGA"
     gene            complement(8206..9723)
                     /locus_tag="G412_RS0120405"
     CDS             complement(8206..9723)
                     /NRPS_PKS="Domain: AMP-binding (17-410). E-value: 1.8e-58.
                     Score: 190.0. Matches aSDomain:
                     nrpspksdomains_G412_RS0120405_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="G412_RS0120405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AMP-binding protein"
                     /protein_id="WP_028813701.1"
                     /sec_met_domain="AMP-binding (E-value: 3.1e-65, bitscore:
                     213.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASTLQEAIAGQACRHDATVTFGTSAKRECLTYPVFAEQIAAAA
                     GGFAQQGVRPKDRVMLRISSSREGVLAFLGLMHLGAIPVSVKPRVPGAITGQYFSMVMR
                     QQRVRHAFRITGHGLNELQLVLRPQATPEPAPADRDDLAFIQYTSGSTGMPRPIPLSHR
                     AVLGNIEAIRTVAGMKPGHAGLIALPLHHDMGLIGVLTSLVQGIDLVVEDPGTFLRRPM
                     AALRLVRDAEGVHSAFPDFMLRYLSARIGEAAEGQEAPDRQLFSAWRTVFCGAEPIRPQ
                     SVRTFLDAAGPLGFDSTALVFCYGLAEAALMATSHRYVDAGASFRADGPTTAACLGSTM
                     PGLDLRIVDESGLDCAEAEVGSVQLRGATLFDGYDGGTDHRTTWFDTGDLGCLRSGRLY
                     LSGRRGDRISVNGVNVFATDIEQVAATVPGVAECVVLPSGESFAVVVVPERARHIDTAQ
                     VATRVAADFGMAPERVIEVTHSAVTRTASGKPARTHMAAELEQGTLR"
     aSDomain        complement(8494..9672)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G412_RS0120405_AMP-binding.1"
                     /evalue="1.80E-58"
                     /label="G412_RS0120405_AMP-binding.1"
                     /locus_tag="G412_RS0120405"
                     /protein_end="410"
                     /protein_start="17"
                     /score="190.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DATVTFGTSAKRECLTYPVFAEQIAAAAGGFAQQGVRPKDRVMLR
                     ISSSREGVLAFLGLMHLGAIPVSVKPRVPGAITGQYFSMVMRQQRVRHAFRITGHGLNE
                     LQLVLRPQATPEPAPADRDDLAFIQYTSGSTGMPRPIPLSHRAVLGNIEAIRTVAGMKP
                     GHAGLIALPLHHDMGLIGVLTSLVQGIDLVVEDPGTFLRRPMAALRLVRDAEGVHSAFP
                     DFMLRYLSARIGEAAEGQEAPDRQLFSAWRTVFCGAEPIRPQSVRTFLDAAGPLGFDST
                     ALVFCYGLAEAALMATSHRYVDAGASFRADGPTTAACLGSTMPGLDLRIVDESGLDCAE
                     AEVGSVQLRGATLFDGYDGGTDHRTTWFDTGDLGCLRSGRLYLSGRRGDRISV"
     CDS_motif       complement(9238..9297)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G412_RS0120405_0001"
                     /evalue="2.10E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="G412_RS0120405"
                     /protein_end="162"
                     /protein_start="142"
                     /score="17.3"
                     /tool="antismash"
                     /translation="AFIQYTSGSTGMPRPIPLSH"
     gene            complement(9720..10145)
                     /locus_tag="G412_RS0120410"
     CDS             complement(9720..10145)
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024675.4"
                     /locus_tag="G412_RS0120410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA thioesterase"
                     /protein_id="WP_028813702.1"
                     /sec_met_domain="4HBT_2 (E-value: 4.5e-13, bitscore: 43.3,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTVTPQEFEHTCEVALRPNDFDWAGHLNNSVHVQLLESGRWQWG
                     LALGVDLRDSSLVAVVLQLQLDYLKAVDWDPVGRLFVRTSLAGQSTYSFTLTQDIERSD
                     GTVVARGRVRLGLVDRDTKQIHRADLRSLLNVPGRAA"
     gene            complement(10142..10480)
                     /locus_tag="G412_RS35320"
     CDS             complement(10142..10480)
                     /NRPS_PKS="Domain: ACPS (7-43). E-value: 8.6e-12. Score:
                     37.0. Matches aSDomain: nrpspksdomains_G412_RS35320_ACPS.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00556.1"
                     /locus_tag="G412_RS35320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="holo-ACP synthase"
                     /protein_id="WP_051338493.1"
                     /transl_table=11
                     /translation="MLDSGVLFTDGERAHCHSRPDPYTSLAGLFSAKEAFVKALSSLGG
                     APAHTFPEVEVVHGPAGQPRIQLHGQIAQWHRQQRLAMEVSISHTGDLAGAVVVLLAEP
                     ARSGGPAS"
     aSDomain        complement(10352..10459)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G412_RS35320_ACPS.1"
                     /evalue="8.60E-12"
                     /label="G412_RS35320_ACPS.1"
                     /locus_tag="G412_RS35320"
                     /protein_end="43"
                     /protein_start="7"
                     /score="37.0"
                     /tool="antismash"
                     /translation="FTDGERAHCHSRPDPYTSLAGLFSAKEAFVKALSSL"
ORIGIN
        1 gggctccgga ttcctcgtgc cgcccgtgga cgggcgcacc atcaaggcgt cgacgttctc
       61 gacccgcaag tgggggtggg tggacgccgc cgcgcccgac ctgttcgtcc tgcgcacctc
      121 catcgggcgc tacggcgagg aggaccacct gcaccgcgag gacgaggagc tggtggaggt
      181 ctcactgcgc gacctggggg cggccaccgg gctcgccgcc cggcccgtcg ccaccgaggt
      241 cacccgctgg atcggcggcc tgccgcagta ccccgtcggg caccccgacc gggtcgcgcg
      301 ggtgcgtggc gaagtcgcga agctgcccgg actgcgggtc tgcggggcgg cgtacgacgg
      361 cgtgggcatc cccgcgtgcg tcgcgagcgg gtggcgcgcc gccgacgaga tcatgctcac
      421 cccggacccg gcgcggggca cggatcaggg cgcgggagaa tagggacatg actgatgctc
      481 cggagactgt gacatccccc cgaggcccga acgccggcaa gaaggccaag gacctcaacg
      541 acgtcatccg ctacaccctg tggtccgtct tcaagctgcg cgacgtcctc cccgaggacc
      601 gggccgggta cgcggacgag gtgcaggagc tgttcgacca gctcgccgcc aaggacgtca
      661 ccgtgcgcgg tacgtacgac gtgtcggggc tgcgcgccga cgcggacgtc atgatctggt
      721 ggcacgcgga gaccgccgac cagctccagg aggcgtacaa cctcttccgc cgcacccggc
      781 tgggccgcgc gctggagccg gtctggtcga acatggcgct gcaccgcccc gccgagttca
      841 acaagtcgca catcccggcc ttcctggccg acgagatgcc gcgcaactac gtctcggtct
      901 accccttcgt gcgctcgtac gactggtacc tgctgcccga cgaggaccgt cgccgcatgc
      961 tcgccgacca cggcaagatg gcgcgcggct tcccggacgt gcgcgccaac acggtcgcct
     1021 cgttctcgct cggcgactac gagtggctgc tggcgttcga ggccgacgag ctctaccgca
     1081 tcgtcgacct gatgcgccac ctgcgcgcct ccgaggcccg catgcacgtg cgcgaagagg
     1141 tgcctttcta cactggtcgg cgtaagtcgg tcgcggatct ggtcgccggg ctcgcgtgac
     1201 gcccttcggc cgggggtccg gggggtgtcc tccgggagat gcggcactgg tcggcgcaag
     1261 tcggtcgcag acctggtggc cgggctcgcc tgagcggcgg cccgccaccc ccgacccgga
     1321 agatcagacg gtgggcgcag gcttcttcgc cactgcccgc ttgtccagcg acaccgggtt
     1381 cggctcccgg tgcggcgcgc attgcgcgcg ccgcaccggc gtccgaccgg tcaggagata
     1441 cgtctccagg tgaccgttga cgcacttgtt cgcgccgccg ccgataccgt gcgtccccgc
     1501 gtcccgctcc gtgaccagcg cggagcccgc cagccgccgc tgaagttcca gcgcgcccgg
     1561 atacggcgtc gccgcgtccc gctcggcggc caggatcagc gtcgggggca gctcacccgg
     1621 ccgcgtaccg acgtccaggg gctcctggcg cggagcgctc cagtacgcgc acggcaggtt
     1681 catccacgcg ttcgcccacg tctcgaaggg cgcgcgctcc gcgagcaggc tgttgtcgcg
     1741 gtcccacacc caccactcgg tcggccaggg cgcgtcattg cactcgacgg cggtgtagac
     1801 ggccttgctg ttctcgtcgt ccttcgcaga ctcgggcctc ggtgacgcct gctcgatcag
     1861 cggcttcggg ttgcccttca ggtactccga cagggccgtg gcgcgcatcg cccagtagtc
     1921 gtcgtagtaa ccggcgctga gcagcgccga ctggagctgg gcggtgccca ccctgccgcc
     1981 cgccggcttg cgggagagcc ccgcgcgcac cttctcgtag ctggcgagga ccgcttcggg
     2041 cgtggcgccc aggtggtacg tcctgtcgtg cttggcgacc caggtgcgga agtccttcca
     2101 gcgcccctcg aaggcgagcg actggtcgag gttgttgcgg taccagatct gtccgggggc
     2161 ggggttgacc gccgagtcga agaccatgcg gcgtacgtgg gaggggaaga gcgtcgcgta
     2221 cagcgcgccg aagtaggtgc cgtacgacgc gcccatgaag gtcagcttcc tctcgccgag
     2281 cgccgcccgc agcacgtcca ggtcgcgggc gttgttgagc gacgtgtagt ggcgcagcgc
     2341 gctgcccgcc gtgcgggcac agccgtcggc gtacgccttg gcgcgggctt tccgctcctc
     2401 cttgtacgcg gaggaagggt gcgccggggc atggctgggc gcctggacga gttccgacgg
     2461 cttctggcag gacagcgggg ccgagcggcc gacgccacgc ggtgcgtagc cgacgaggtc
     2521 gtacgccgcg ccgatccgct tccactcggg caggacgccc gccatcggga agaacatgct
     2581 ggacgcgccg gggccgccgg ggttgtagac gagcgcgccc tggcgtgcgg cgggcttccc
     2641 ggtcgcgcgg gcgcggctga cggtcagtga gatctggcgg ccaccggggt cggcgtagtc
     2701 gagggggacc ttgaccgtgc cgcacctgac gtgtttgggc aggccctcgg acgcggggca
     2761 ggcgccgaag gcgatgccgg cggcggccgc gcggtgggcg gcgagcgcgg tgccgcgggc
     2821 ctcgggggag gcggcggact cggcgctgcc ggcgggggcg gcgacgaggg cggtcaggac
     2881 cagggagccg acggacgcca gggtcccgta catggccagt gctctcatcg cgttcccttc
     2941 gcgtgcggtg caggacaaaa gggatacttg gcgggggagt tggcgaagta aagcaccggt
     3001 gggcggtgtc ggggtcaatg accccgacga gccgcgaggg cggcacgcag gtgcggatcg
     3061 tcgacagcgc gtacgccgag acgggcgacg gcggtcagga acgcgcgctc cccggtgcgg
     3121 tggccgggcg cgagcgcgtc gagcacccgc cggccggcgg gggaggccca gccggtgtac
     3181 gtatggatct cgaaccgggc gatggcgagg cagcccaggc tgaggccgag cgggagcgcg
     3241 aaccaggcgg cgaccaggcc ccggcccgcg gcctgctcct ggcccggcag cagcagggac
     3301 gcggcggcca gggccaggac gagcagggtc gcggcccgca cggaccgtac ggcggaggtg
     3361 aggggggcgc gtacggcgtc ggggacggcg aggcccgcgg agaccaggcg gtcggccacg
     3421 gcccgtacgg cgtcggcggt ggtcgtggcg gtacgtatcg ccgctaccgg ggactggccg
     3481 gccgggccga ttgcgcccag caccgagcgc tccacatcgt cctcgccccg tgggtcgacg
     3541 acgacggtcg cccagccggt gtgcgcgagc agcagccggc ggcggcggtg catcgacacg
     3601 agggccaggt ccgcgactct caccgggccg ccggcgagga acgccgtctc gtagaggctc
     3661 agttcgtaat cctggggcgc gggcgcgggc cgtgcggcgt ccacgggccg ttccgggtgg
     3721 ccggcggcga cggaagcggc gaggcagagc cgggcgcagg agaccgcggc cgcgacacag
     3781 gccacgatga ggaaaagaac ccagaacatg gcggagttct acgcgacaag cccaccggaa
     3841 agccatggcc ggctcacgat gtggaccatt ccgtcgtggc ttcgtggcgt cgtggcttca
     3901 tgaccgaatg gtccgccgcg acctcgcgga agtgatcggc gggtcgctcc gccacccgtc
     3961 aggagctgct gccgcagctt gagcccgagc tgcaactcga accggagctc gaaccgcaac
     4021 tggatccgct gccgctgccg cagctcgacc cgccggagct gcttgagcag ccggaaccgc
     4081 ccgatcggga gcccgaatcc cccgagctgc tgccgcagct cgaagcgccg gaggcggagc
     4141 ccgcgcacca caccatggcg gcggccgcgt aagtggtgct ggtgccgctg tccgtcgacg
     4201 gcgtacggga cgtggtgcgg gacgtggtgc gggagccgcc cggtgtcagc cgcgccgccg
     4261 tgtgcaactg ctcccacagg gcgcggtcgg gcagcgcccg caggccgcgc accgcgacga
     4321 ggtggccgga ggcggtccgg tccgcgtgcg aggcggcgta cgcggcggcc gccgcgcggc
     4381 ccgccggggt gacacgggcg gccgccctgc ccgcgttgac ggcgccgcac acgattcccc
     4441 agaccagcgc gggcagcacc agggtgatga acgggacggc ggaatgcccc gcgacgctca
     4501 ccgcgatcgc agtcacgatg cacgcgggca gaccgagtat gcaggtgatc agcaggacga
     4561 tactgccggt gcgccacttg cggccggcct gcggcggcac catcaggccg cggaacgcga
     4621 ggctgtcgcc gatctcctgc accgcctcgc cgcgcatgac ggcgtaccgc aggttgtgca
     4681 gcgcgccgtt gggtgcggcg gcgagttcgg cgtacacgct ccgctccacc gggccgtggg
     4741 cgacggtgct ccgtgccgag acgatgccgg ggccgccgat cgcgaggcgg ccgtcggagt
     4801 gcatcgtggc gagtgcggtg tccacgaccc tggaggggcc gccgttcagg aacgcgacct
     4861 ccatgaggtc gtggaggggg acgggcccgg tgccggccgg gccgcggcgg agggcggagg
     4921 tgccccggaa caggatgatc gagaccgcca cgatggcgag tgcgatgagc agggcgagga
     4981 cggtcgtggt catcggcgcg tcacttcctg acgagtgcgg cacgcgccgc acggacgaat
     5041 cgggtcgtac ggcggggagg gcgcgggccc gcgcggtcct gccaccagac ggtcagttgc
     5101 ctgcgggcgg cctcgtcccc cggccggccg gtggccagca ggtgctcggc gaagtcaagt
     5161 gcgtcacgcc ggtaaccggc cgacatgggc cgggacttgg cgtacgccag gaacgcgtcg
     5221 cggtaggcgg cggcccccag gagctgcggg agctccgggg cgaccttggc cacgacgtcg
     5281 gcccgcttcc cggcgagcgc acggctttgg acgcgcaggc gcgcggagtc gaagccggcg
     5341 gggacggggg ttccggcgac gagggcggag agaagcgcgg cctgcgcgag cgcgacccgg
     5401 atacgggcgt cgtcaccccg ccgagcaccc gccggcaccc cgacgacggg gtcttcgccg
     5461 cgctcgggag ctgcgggggg cgtggcctgc ggccgctcgg cgcgctgtgc cgggggcgtc
     5521 agggctgtgc ggattctggt cagttccctg gccaggtcct ccgtgggcgg gaagttgtcg
     5581 tcgcgctcca ggaggacgcc cggcgggtcc gtgcgggagc gcaggtccgt caggatgtcg
     5641 aggaccggcc gggacacggg gtgggcgtgc gtgtcgtgcc agacgccgtc cttttcgatg
     5701 ccgcccgcca cgtggacgta cgcgatcgcc tccaccggga gctcgtcgag cgccgccgaa
     5761 ggatcctcgc cgcggttcac gtggttggtg tggaggttgg ccacgtcgat caggaggcgg
     5821 acgccggtcc gtgacaccag ctccgccagg aactgaccct ccgtcatgtc ctcgtccggc
     5881 cagttgatca gcgccgcgat gttctccagc gccagcggca ccggcagcga gtcctgcgcg
     5941 atgcgcacgt tctcgcacag cacgtcgagc gcgtcccggg tgcgcggcac cggcagcagg
     6001 tgcccggcct ccagaagcgg gcttgccgtg agggggcctc ccgcccgtac gaacgcgatg
     6061 tgctccgtga cgagaggggc gcccagcgcc tcggccgtcg ccgccaggtc cgccagccgg
     6121 gccgcgtccg ggcggtccgc gccgcccagg cccagcgaga cgccgtgcgg gatcaccttc
     6181 gtaccgcggg cgcgcaaccg gaggatggag tcgggaaggt ggccggggca gaggttctcc
     6241 gccaccgcct cgacccagtc gatgccgggc agcccctcca ccgcgtcggc gatctccggg
     6301 cgccagccga tacccgtacc gagacgtcca agacgttcca tgtgtccccc tcctctgctt
     6361 cgtgcagggg taatggcccc ggcgcgccgc gccgaatcca gaggagggga cgttcagagg
     6421 ttgatttgag gttaggggga aggctcgggg cggttcgtgt tgaccgccgg gctgccgatc
     6481 tcgccctccg gctgcgcgga cggccgggag gtgaaggtct ggtcaccggt cggtacggcg
     6541 gccggcggcg acgggaccgt caccgagccg tcgggcggcg ggggcccggt cgggctcgcc
     6601 gtggtgttgc ccgcggcctc gttcgccagg gcgtcgaagt cgaccagacc ggtggcctcc
     6661 agcatggtga tgtggtcgag gacggtctgg ttcgcgtcgg tcgccaactg ccgtatcagc
     6721 gcgttgcgcg tggtgtgccg cacctgggcc acgagggaga agaccttgcc gtgcgcgttg
     6781 cgcaggaggt tggcgaactt gcgctcgtac tccggaccgc tcgccgccga cagctccctg
     6841 agccacccct gctgctgctc gttgggctgg ttcggcagcg gaacgttgag ctgcgcggcc
     6901 accgaacggg cccgcttgtc gaggtccgcg tgaccgacga ccaggtggtc accggcctcc
     6961 ttgatcgcct cactcggggc gcgctcgatc gcctgctgtc cggccggcag ctcccacagg
     7021 cccgccagcc gcaccttcac caggaagtcc cggtcggtgg cggacagcgg gccccactgg
     7081 gtggcgaccg tggaggcgtt gaggttggcc tggccggtgc ccgagcggtc cgcgtaggac
     7141 cacaccggga aggcgagtgc gccgatggtg gcgacaagtg ccgcgatgat gagtgctgtt
     7201 ccgttgatgc gtcgcaacaa agtgtctccc gagccgatgc gttacaccgt cgaaccaacc
     7261 gcctgccgag cggccggaca acctacttgc aagtattcgt aggtacgtgt gacgcagccg
     7321 acgcgttcaa cgccgcgcgg cgaaaatccg gttcaggccc cgcgccgccc ggcgacgcag
     7381 cgcggtgacg cggacagctc ggtggtgtgc aggtcgacga tgagcaggcc aggagcagcg
     7441 tcgagctggt gccgcacttc cccggatggc gaaacggcca tgctgcgccc gatccccagg
     7501 ggttcggtgc cagggtcccg gccaatggac cgcggtgagg cctgatcgca agcgaggacc
     7561 caggcaccac tgtccagtgc gcgggcgcgg accagaacgt cccactggtc cgccttcccc
     7621 gggccgtcgg cccaggaagc gggcagcagg atggcctgcg caccccgcgc ggccagctcg
     7681 tggaagaggc tggggaagcg gacgtcgtag caggtggcga cgccgaaggt caggccgttc
     7741 aactggaagg tcacaggctg tcggccgggc gccaccgtct ccgactcggt gtagccgagc
     7801 gcatcgaaga ggtggatctt gtcgtagtgg gtgtcgacac ccggccctgt gatcagcagg
     7861 gtgtttctga cccggccgcc gtcgcccgga gtgaacatgc ccacgacgac ggtgagaccg
     7921 gctctggccg acatggcgcg tacggcctct gcccacggcc ccttcagcgg ctcggccaca
     7981 gcggcgagcg gggtcccgaa gcgggccatg gccgcctccg gaaacaccac gaggtctgcc
     8041 tggtgcccgg ccgcctcggc gataccggcc tcgatgatct cgagattccg ccggggatcg
     8101 gagtcggaca gcatctggtt caacgctatg cgcaacggcg tgccctctct acggcgcaag
     8161 cgcggcccgc gtaccggccc atgtgcttgc aggcactgac gggggtcatc gcagagttcc
     8221 ctgttcgagt tccgcggcca tatgggtacg ggcgggcttt ccgctcgccg tccgggtgac
     8281 ggcgctgtgg gtcacctcga tcacgcgctc cggagccata ccgaagtcgg cagccacacg
     8341 ggtggcgacc tgggcggtgt cgatgtgccg ggcccgctcc ggcacgacga cgacggcgaa
     8401 tgactcgccg gacggcagga ccacgcactc ggcgacaccg ggaaccgttg cggccacctg
     8461 ctcgatgtcc gtggcgaaga cattcacgcc gttgacagag atacggtcgc ctctgcggcc
     8521 gctcagatac aaccggcccg accgcagaca ccccaggtcg cccgtgtcga accaggtggt
     8581 gcgatggtcg gtgcccccgt cgtagccgtc gaacagcgtg gctccgcgca gctgtaccga
     8641 gccgacctcc gcctccgcgc agtcgagtcc cgactcgtcc acgatgcgca ggtcgaggcc
     8701 gggcatggtg ctgccgagac acgcggctgt ggtgggcccg tccgctcgga agctggcgcc
     8761 cgcgtccaca tagcggtgcg aggtggccat cagcgccgcc tcggcgagtc cgtagcagaa
     8821 caccagtgcc gtcgagtcga atcccagggg cccggcggcg tcgaggaagg tgcgcaccga
     8881 ctgcgggcgg atgggttcag ccccgcagaa cacggtgcgc caggcgctga aaagctgccg
     8941 atcgggtgct tcctgtccct ccgctgcctc cccgatccgg gctgagagat aacggagcat
     9001 gaagtcgggg aaggcgctgt gcacaccctc cgcgtcccgc accagccgca gtgccgccat
     9061 gggcctgcgc aggaaggtgc ccgggtcctc gaccaccagg tcgattccct ggaccaggga
     9121 ggtcagtacc ccgatgaggc ccatgtcgtg atggagcggc agggcgatca gcccggcgtg
     9181 gcccggcttc atgcctgcga cggttcggat ggcctcgata ttgccgagca cggcacggtg
     9241 gctgagcggt atgggacgcg gcattccggt ggagccgctc gtgtactgga tgaacgcgag
     9301 gtcgtcacgg tcagccgggg cgggctcggg cgtggcctgc ggacggagca ccaactggag
     9361 ctcgttcagg ccgtgtccgg tgatgcggaa agcatggcgc acgcgctgct gccgcatcac
     9421 catcgagaag tactgcccgg tgatcgcccc tggaacgcgc ggctttacgg agacggggat
     9481 cgcgcccaga tgcatcaggc ccaggaaggc aagcacaccc tcacgggagc tgctgatgcg
     9541 gagcatcacc cggtctttcg ggcgtacccc ttgctgcgcg aagccaccgg ctgccgccgc
     9601 gatctgctcg gcgaacaccg ggtacgtcag gcactcccgc ttggcggagg taccgaaggt
     9661 gacggtggcg tcgtgccggc aggcctgtcc ggcgatggcc tcctgcagcg tgctcgcggt
     9721 catgccgccc ttcccggaac gttcaacagg gaccgcaggt cggcccggtg aatctgtttg
     9781 gtgtcacggt cgacgagccc cagccggacc cggccccggg cgacaacggt gccgtcgctc
     9841 cgctcgatgt cctgggtgag agtgaagctg tacgtggact gccctgccag cgacgtacgg
     9901 acgaagagac ggcccaccgg gtcccagtcg accgccttca ggtaatcgag ctggagctgc
     9961 aggaccacgg ccaccagaga gctgtcccgc aggtcgactc ccagggcgag cccccactgc
    10021 cagcggcccg actcgagaag ctggacatgc acactgttgt tcagatgtcc ggcccagtcg
    10081 aagtcgttgg ggcgcagggc gacttcacag gtgtgctcga attcctgtgg tgtgacggtg
    10141 ttcatgaggc cggccctccg cttctcgccg gctcggccag gagtacgacc accgcaccgg
    10201 ccagatcacc ggtgtggctg atcgacactt ccatggcgag gcgttgctgc cggtgccact
    10261 gggcgatctg cccgtgcagt tgtatccggg gctgccccgc agggccgtgt accacctcca
    10321 cctcgggaaa ggtgtgggcc ggtgcgccgc ccagggagct gagcgccttg acgaaggcct
    10381 ccttggccga gaacagcccg gccaaggagg tgtacgggtc agggcgggag tggcagtgcg
    10441 cgcgctcgcc gtcggtgaac aggacgccgc tatcgagcaa gtgcggcttc gcgcgcagct
    10501 ccgttacgga ctgcagatcg aatccggtcg acatcgttcg tccgcaggct ggcgaagtag
    10561 gcacgcttga gatcctcata cgactgggtg tggattccgg tcacctcgcg gaccagggcg
    10621 aacacgctgg tcagcttctt cgcgtgcacc gaaccctcgt gcagcgcctc gtcgccgagg
    10681 ccgaactcct cctcggcggt gcgggtccgc tcccaccagt tcacgaagcc ctcgcgctcg
    10741 gtctgggcgt cacgggccga gccgaacgtc tcgccgccgt cgggacggac ccaggtgtac
    10801 gccatcgaca ggacgtcctt gatggggtag accccggact ccacgagcgc cttggcgaag
    10861 gaggcgaagt actgccggtg ctgcacctcg tccttcatga ccgtgtggaa gacgtcacgc
    10921 accaggccgt ccttggtggt gcgggactgc cagccgtacg acacacacgc ctcgatctcg
    10981 acacacgcct ggagaatgca gacccgcgcg tagttgtcgg tggggaaagg gccccggtgc
    11041 tcgatcacct cgccctcgtc gatcgggtcg atgcccgcca tctccatgag ccggccgaag
    11101 gcgacctcgt ggtgcgcctc ctcctccagc cagtagcgcg ccgaccaggc cgcggcgatg
    11161 tgcaggacgt cggccccgag cgggttcgac tcgcgtattt cgccggccag cttgacgccg
    11221 tccacggcga gccggatacc ggcgggctgg gtggtcagct cggcgcggga ggcgtgccac
    11281 agcgcggcct tgtcgccggg ggccggacgg gacagccggc ggccgtcgaa gaggttgtcc
    11341 g
//
