LOCUS       NZ_AUBE01000012        28244 bp    DNA     linear   CON 22-APR-2024
DEFINITION  Streptomyces flavidovirens DSM 40150 G412DRAFT_scaffold00011.11_C,
            whole genome shotgun sequence.
ACCESSION   NZ_AUBE01000012
VERSION     NZ_AUBE01000012.1
KEYWORDS    WGS; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces flavidovirens DSM 40150
  ORGANISM  Streptomyces flavidovirens DSM 40150
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 241428)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUL-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            environment                       :: Soil
            investigation_type                :: bacteria_archaea
            project_name :: Streptomyces flavidovirens DSM 40150
            sequencing_meth                   :: WGS
            ref_biomaterial                   :: DSM 40150, ATCC 19900
            finishing_strategy                :: Level 1: Standard Draft
            GOLD Stamp ID                     :: Gi11969
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2012
            Isolation Site                    :: Soil
            Sporulation                       :: Sporulating
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Unknown program v. before 2013-03-07
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000429085.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 01:37:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,525
            CDSs (total)                      :: 6,452
            Genes (coding)                    :: 6,216
            CDSs (with protein)               :: 6,216
            Genes (RNA)                       :: 73
            rRNAs                             :: 6, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 236
            CDSs (without protein)            :: 236
            Pseudo Genes (ambiguous residues) :: 0 of 236
            Pseudo Genes (frameshifted)       :: 106 of 236
            Pseudo Genes (incomplete)         :: 173 of 236
            Pseudo Genes (internal stop)      :: 25 of 236
            Pseudo Genes (multiple problems)  :: 59 of 236
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:04:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 81971
            Orig. end                         :: 110215
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AUBE01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     region          1..28244
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="crocagin"
                     /region_number="1"
                     /rules="(PhyH and Carbam_trans_N)"
                     /tool="antismash"
     cand_cluster    1..28244
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PhyH and Carbam_trans_N)"
                     /kind="single"
                     /product="crocagin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28244
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:18244](+)"
                     /cutoff="10000"
                     /detection_rule="(PhyH and Carbam_trans_N)"
                     /neighbourhood="10000"
                     /product="crocagin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..18244
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PhyH and Carbam_trans_N)"
                     /neighbourhood="10000"
                     /product="crocagin"
                     /protocluster_number="1"
     misc_feature    984..1004
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.09"
                     /tool="antismash"
     gene            1361..1741
                     /locus_tag="G412_RS0118070"
     CDS             1361..1741
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019074009.1"
                     /locus_tag="G412_RS0118070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_028813305.1"
                     /transl_table=11
                     /translation="MVTKQFTGAPEEADLRRADSLAREIFSDVANKWAFLIIESLGEGT
                     LRFSELRNDVEGISHKMLTQNLRMLERYGLVERKVHPTVPPRVEYTLTEPGQALRATVD
                     GMCGWTHQYLGHIEASRRRFDA"
     gene            1862..2620
                     /locus_tag="G412_RS0118075"
     CDS             1862..2620
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010043927.1"
                     /locus_tag="G412_RS0118075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IclR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_028813306.1"
                     /transl_table=11
                     /translation="MAAHDGPTLITSVQRAFRLLEAVSAHESGAPAKQLARETGLPLAT
                     AYHLLRTLAHDGYVRKLDDGGFVIGDQLDALRAGGRVQTLLSRIRPALAALRDDLSAAA
                     YLTFYEEGEIRIAEIVDSPRAQRVDLWVGFEDAGHATALGKCVLREMDEESRNDYLSRH
                     SLEDLTPRTITHRSELIRRLESSTTDPAVTDLEEYSLGTVCMAVPVYSGGVLGSLGVSM
                     RADRLSRLDEVRARLLPTASRVTRGLSLTI"
     misc_feature    complement(2753..2767)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.83"
                     /tool="antismash"
     gene            2870..3847
                     /locus_tag="G412_RS0118080"
     CDS             2870..3847
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129775.1"
                     /locus_tag="G412_RS0118080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_244283111.1"
                     /transl_table=11
                     /translation="MVWLPLLAAGPALAAATTRLPGVLCVGFLAAVLGAVLGIRDGVPG
                     RELAIVLSALVAVTLASGLASGLRVRRERVLAAVRSVAEAAQHALLKPVPATVGQFQVA
                     VRYSAAEAEARIGGDLYALVPTPYGVRLIVGDVRGKGLPAVGTAALVLGVFREAAYDEP
                     DLLDVVGRIERSLARNLGSDDFVTAVVAGYPGAGSMEVVNCGHAPPLMVRDSDVLVVEP
                     THPAPPLGLRALTGESPSLQILPFADGDQLLLYTDGVTEARNHAREFYPLVERVARHLS
                     DEPSRTLAALHDELLAHVGGRLHDDAALLLLRKPAAVGSAASAA"
     gene            complement(3913..4262)
                     /locus_tag="G412_RS38230"
                     /pseudo=""
     CDS             complement(3913..4262)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008745670.1"
                     /locus_tag="G412_RS38230"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAGVITAAEPSWTAPLTGLSPRALSKLVTQLRREGADAPGRGRPW
                     RLPLADRVLLVGAYWRTNPTGATTSEFRSASSTPSPV"
     misc_feature    complement(3921..3923)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4335..4718
                     /locus_tag="G412_RS0118090"
     CDS             4335..4718
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521001.1"
                     /locus_tag="G412_RS0118090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_028813308.1"
                     /transl_table=11
                     /translation="MGLMLFPGDEDVASPDISWSYTGFSMFRKWLAQAEGFTLAEMDGF
                     GGDRQWCSVSTTLAPLLNHPDDGGPHLAPAQCAAMLPRLEAILDQHQPDDSDPALRRRI
                     EDVSQLVTVLRFCVDKDVELIFG"
     gene            complement(4916..5404)
                     /locus_tag="G412_RS0118095"
     CDS             complement(4916..5404)
                     /GO_function="GO:0043169 - cation binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192551.1"
                     /locus_tag="G412_RS0118095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hemerythrin domain-containing protein"
                     /protein_id="WP_037649144.1"
                     /transl_table=11
                     /translation="MTDVVELITQDHRRMEDLFRAMRSVEEDRAAALREFADLLIAHGE
                     AEEAEVYPALRRYRKVDNDEVDHGEEEHTEGNKALAALLEVPEVGSEDWDEKLEELSEA
                     ITHHLDEEERTLLNHARELVADDRRAELGEAFARERERLLKEGCGSLENVRKVIAASE"
     gene            complement(5632..6495)
                     /locus_tag="G412_RS39720"
     CDS             complement(5632..6495)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012863.4"
                     /locus_tag="G412_RS39720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_157839128.1"
                     /transl_table=11
                     /translation="MGKTRSALRITALALAGAMAVAGAGTAQGAGPPRPMKYVALGDSV
                     AAGIGAGSPTANSHNCWINEEAKIRVPNSTKAYPRRVAAALGAQLDFQAYCGATVSGVR
                     NNQTRTLSKRTKLVTVQVGANDFGFADVLLECAVLGRPCMDDLRWIQQQYLNVLPGRLD
                     KLYDKIGLKAKNAKVVVVGYPKLVTPTFNPTCLGDGGLPNDVRTEMNGAAHTLNDVLRI
                     EAGKHEFDFAEVEPSFKGHAICEDPEWINGFSNPLVESYHPNAAGHQALGWLVWQRVKP
                     TAWNRP"
     misc_feature    complement(6617..6633)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.16"
                     /tool="antismash"
     misc_feature    complement(6882..6898)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.68"
                     /tool="antismash"
     misc_feature    6882..6899
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.88"
                     /tool="antismash"
     gene            7067..7450
                     /locus_tag="G412_RS35035"
     CDS             7067..7450
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025384.4"
                     /locus_tag="G412_RS35035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4234 domain-containing protein"
                     /protein_id="WP_051338445.1"
                     /transl_table=11
                     /translation="MSTDVRTSAPAGAPSSPVVTWLLTLVTLGIYWLVWYYKVNKQVKA
                     IDPTIEVKPGMAVVAVTLGSLLIIPPFVSIVKTGSRIAQAQRAAGVTSDYCSGIVGLLL
                     AFVLGLTPLYYQSKLNTVWADRA"
     misc_feature    complement(7904..7918)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            8103..8270
                     /locus_tag="G412_RS39725"
     CDS             8103..8270
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS39725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157839129.1"
                     /transl_table=11
                     /translation="MAEVRKVVRPAVTASSRPCAFVSPDKGNAPTITPVRKDVQAAPAA
                     AEQRKQDTPA"
     gene            8413..9972
                     /locus_tag="G412_RS0118110"
     CDS             8413..9972
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018555032.1"
                     /locus_tag="G412_RS0118110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_028813310.1"
                     /sec_met_domain="TIGR04085 (E-value: 4.7e-09, bitscore:
                     30.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.5e-06, bitscore: 22.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNSIYQSSLYVRTLRSAEDRDFTAFGGRLGTYDGSERTMAFHSL
                     YGNARLVDRDIVELLKDAANGMTPEQLLERIDEASLRDLIEARYLVEAGRDEAEEINAL
                     LESRQAVLSSGVFHSSIQLVLTNACNFSCQGCFAYNFDGGVEERNTSGETVKPGPVLVE
                     LRRSRPDSGPTLAKGDWNHGSDSGRNPSMHMSLDVAEKTVKEAIALRKANGGGHLTVSF
                     FGGEPTLARGTILHVLRTFGDSYDGVSLSYDLTSNGSRIDDELLAALARHKVDTTVSID
                     YLVPETGEFRGGQQQRTAWPVVRKAIVDMKAAGVPVSITTVLSQFTWDKWGTPLIDFVA
                     EAGLDSLDVIVSFQAKEFFDRHSPHDVAQRLLHAVDYGRERGVQLSGYWYQTFQMIIDE
                     RKWAAQADYKTCPAVGRQLSIEPNGSVFACKATARKLGTIDDWQGIFASDAYQDYGMRA
                     YTNGPGCQGCELQGTCSGGSAGALEEENGSIQLMSPGYCAYMREVVQGLLERHHAQTAA
                     FA"
     gene            10001..11851
                     /locus_tag="G412_RS0118115"
     CDS             10001..11851
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     crocagin: Carbam_trans_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602580.1"
                     /locus_tag="G412_RS0118115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbamoyltransferase C-terminal domain-containing
                     protein"
                     /protein_id="WP_244283092.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 1.1e-26,
                     bitscore: 87.8, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATIGMHFGHDAGAALTQASGYHVIEAERRLGLRHVCGGNEQFAR
                     TAADWLAELRDRAESPVTRVAVADWYTPVCRVLPPALVELVGKDAWWARPGGNLLNAVV
                     RPVDLAGWPLAECLGQVELTVVRHHYAHAALAYYTSGARKALVIALDGTGNYAENGMVC
                     LGEGDRLTPVLSFTNRSCPRFGLVYEALARRVHGSQFDTGKLLGLSATGEPDPALLPVL
                     RAMLVPQGARTRSPDLYEPLDEDMLAGTALRYADSSWEYDPDSGGYLDAGLADSSDDDV
                     VHSYGSVFPDEIRTADGRRTEVGSSPGDRVCRDLAATLQAAVERDLVNLVTGISARFPG
                     YSTLCYAGGCALNITANSALVESGQFTRVHIPTCCDDSGIALGAALAAADPAQRPAPAA
                     GPPGAHLVYAGAPLAVAEDGARNSALRAGRAVRTWATAVAFTEAVAELLAGRGCVAWLE
                     GGMETGPRALGHRSLLVSAHWSGARQYVSQTIKGREWFRPVAPLCPAEDAERYFTGPLD
                     HTDTMLFAVRVKLERAELLGEVRHIDGTARLQTVRPASHPALHGLCRAVGARTGLPVLI
                     NTSANGGGRPILNHLDDALELLAGTALDAVVLPEQRLVIE"
     gene            11967..12854
                     /locus_tag="G412_RS0118120"
     CDS             11967..12854
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     crocagin: PhyH"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602579.1"
                     /locus_tag="G412_RS0118120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_208857901.1"
                     /sec_met_domain="PhyH (E-value: 1.9e-08, bitscore: 28.5,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTVQLRDIHKSLNLRVLSPQDWDQWTTEGYVVVRETVPERNVTR
                     LTEALWDFQDMRPDDPSTWSSAHTGNERLPGHSGLVEMYNHQAQWDNRQTRRVYDAFVD
                     IWDRTDLWVTIDFANVNPPNHGSRAFAGFVHWDVDTSVDPLPVSCQAVLSLTEGNEDIG
                     GFQCVPEIFTEWDTWVKGQPEDRDPYTPDITGYGITTPRVHPGDLIIFNSLLPHGVHPN
                     VSRDQVRMAQYISMAPAWEENEALREARVRFWRDRVPPHPPEGGLRKEEHTLYGPAELT
                     PLGERLLGLRSWHE"
     gene            12929..14224
                     /locus_tag="G412_RS35045"
     CDS             12929..14224
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602578.1"
                     /locus_tag="G412_RS35045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_051338446.1"
                     /transl_table=11
                     /translation="MASATPGTSAARPGLGGPFRWLWVSTAASNAGDGVTRTLLPLLVV
                     ASHPEPAAVAGLTAVNMLPWLLFALPAGVLVDRLDRRRIVLWSNLLRGAVLLGAMAVLA
                     GDRPLAVLYVLAFVLGIAETLADTAAPAMLPRIVGQRDLERANGRLSAAQIVFNDMAGP
                     PVAGLLVGVAATAALATGGVLYAMAAVLLLGLVTVERDRAGQATSGPAEPVRTGIRAGL
                     RFVLGHRTLRLTLAASALYGLVFSATFSMLVLLSHRTLKLDATGYGLLLTAGSLGAVGG
                     SWLAPKLAERLPVVRLARWCLVASGLAYAALGLARTPAQAAVALLCNGVFMMGWNIPVM
                     SLRQRLTPEEFQGRVMSVSRLCAWGAMPVGASLGGLLAEALSVPAVFVICGGVLAAGAL
                     LLLAPLRADGYDGPAVQAGPHPRQNSDPSTKE"
     gene            14228..15160
                     /locus_tag="G412_RS0118130"
     CDS             14228..15160
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602577.1"
                     /locus_tag="G412_RS0118130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_028813313.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.1e-26, bitscore:
                     85.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEPYDTVIVGGGPAGLNAALYLGRSCRRVLLVDSGDARNMAAG
                     VMHNVLTNDGVDITDFRARARAELGAYDVAFRDDEVVSVEPDGDHVVTTTKESGTFRSR
                     TLLYAAGVRSELPPVPGLAGLWGTSVFECPYCHAWEVRGTSFGVYGGVVPGECLAATLT
                     VWSDSVTYLSDRRELPEDERERLTAAGIPTVTDKIARVSAHPEGVAVELADGRSLTFGA
                     LFLHMDTEPRVEPLRPWLRSDDLESVQTDERGRTRLPRLYVAGDLGKNMQQAAMAAASG
                     GLAAMAINADLIREDRPGSLPAPPPAPAP"
     gene            15209..16126
                     /locus_tag="G412_RS0118135"
     CDS             15209..16126
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018555037.1"
                     /locus_tag="G412_RS0118135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_028813314.1"
                     /transl_table=11
                     /translation="MQSPRAQLAPQMEHYTFVLEDQPYLGFFQYGNENTPVYSTDEHGF
                     RVTRGPGDAAATVSGERPPGPVRLLAGSSATFGVGATGDAATVPSRLWTRHAPRLPWLN
                     FSGQSHNSAQELMLLTLFRHHLPEVADIVLFSGVNNLVLSRLPTEQQGRHGAFFECGAA
                     PDTVPTPEERIDRAAGLTVRHLSTWKLLATAMGARLTFVLQPLAPWVRDEPTPQEKLLF
                     DELDDVSNFRRLHNDISTMEVGRKYAEVIGAGCAGLDVPFLDMNAALAEATTPDEWLFI
                     DRVHCTDLGYDTVARLLAGHLDLT"
     gene            16137..16298
                     /locus_tag="G412_RS39730"
     CDS             16137..16298
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G412_RS39730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157839130.1"
                     /transl_table=11
                     /translation="MSVIRRLLGRLRRRPPTAARPPERSRTPRQDHQDRRSGLRPQSED
                     DASIYPLF"
     gene            16367..18244
                     /locus_tag="G412_RS0118145"
     CDS             16367..18244
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     crocagin: Carbam_trans_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018516190.1"
                     /locus_tag="G412_RS0118145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbamoyltransferase"
                     /protein_id="WP_028813315.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 7.9e-88,
                     bitscore: 288.9, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELILGISAYYHDSAAAVVADGVPLAAAQEERFSRRRHDPRFPA
                     GAVDYCLRAAGAKLGDIAAVAFYEDSALKFRRALATWLATAPRGFPAFHDAFPQWLAWK
                     RNATGEVRRNLRARAGDGGALPPVVSGRHHASHAASAFYPSPYESAAVLCVDGVGEWAT
                     TSMWHGRGTRLSALGELRFPHSLGLLYSAFTYFCGFKVDSGEYKLMGLAPYGKPRYAQL
                     IRERLIDIKPDGSFRLDLRHFSYVYGRVMTGRGFEELFDGPRREPEGPLTEREFDLAAS
                     VQQVTEEVMLRLARTVCERTGERRLCLAGGVALNCVANGRIVAEGLCDEVWVQPAAGDA
                     GGALGAALAESHRRGAPRAHVGRRTDAMSGALLGPAYAAEEIAGFLDRHGVPYTRLSGD
                     RLARRVAAEIAAGRIVGWFQGRMEFGPRALGARSILADPRDPGMQSTLNLRIKFRESFR
                     PFAPAVLSEDAARWFDLRQESPYMLLTAQVAAEQCRDGDGDGDGDGADAGAGDDLTGLG
                     LLRVRRSTIPAVTHVDRSSRVQTVGPHDNPPFRRLLTAFRDLTGCPLLVNTSFNVRGEP
                     IVNTPQEAYTCFMRTGIDLLVLGDFLLEKQDQPPWRDKEDDWRDAIPMD"
     gene            18222..18380
                     /locus_tag="G412_RS40205"
     CDS             18222..18380
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490385.1"
                     /locus_tag="G412_RS40205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167546472.1"
                     /transl_table=11
                     /translation="MTRSRWTDLARRPALAALYFLVLTPIGLCVRRIRDPLRRSWHACA
                     TTYWDHP"
     gene            complement(18437..19465)
                     /locus_tag="G412_RS0118155"
     CDS             complement(18437..19465)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005320801.1"
                     /locus_tag="G412_RS0118155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_028813316.1"
                     /transl_table=11
                     /translation="MIRGTDGKRRSVTIHDVAREAGVSRGTVSRVLNGGHYVSPAAQAA
                     VNAAIRKTGYVVNRHARSLITGKSDSVAFLLTEPQERFFEDPNFNVLLRACTQALAARD
                     IPLLLMIAGTEAERRRNLRYIEGGHVDGVLLVSSHSGDPVVSELDAASVPVVACGKPLG
                     QRARVSYVAADDRDGARSMVRYLHDSGRRRIATVTGPADTPGGVERLAGYRDVLAECGL
                     PVDESLIVPGDYSRASGEAAAELLLERAPDMDAVFVASDLMAQGVLDTLSRGGRRVPED
                     VAVGGFDDSPAALSTRPGLTTVRQPWDRISTEMVRMLLARIAGEEPSAVILPTELVRRG
                     SA"
     gene            complement(19491..20390)
                     /locus_tag="G412_RS0118160"
     CDS             complement(19491..20390)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474661.1"
                     /locus_tag="G412_RS0118160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_028813317.1"
                     /transl_table=11
                     /translation="MSTLLKAAPAPGTTPGTSQGPPGPRRTALLPTAALLLGALYCLLP
                     VAWVLVASTKSGTELFSTFTFLPGTGFADNLADLGAYRDGIYWRWMANSALYAGLGALL
                     STIVSALSGYALALYRFRGREAVFNVILAGVLMPPVILAIPQYLLMAKAGMTDSYLSVL
                     LPLILSPYGVYLGRIYAGAAIPTELVEAGRVDGAGEWRIFLRIAVPMMSPGLVTIFLFQ
                     FVAIWNNFLLPFIMLGDDEKFPMTVGLFTLLSQGSNTPALYTLVITGALLAIVPLIALF
                     LVVQRFWSLDLLSGAVKS"
     gene            complement(20387..21328)
                     /locus_tag="G412_RS0118165"
     CDS             complement(20387..21328)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005320805.1"
                     /locus_tag="G412_RS0118165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_028813318.1"
                     /transl_table=11
                     /translation="MTATRRKARGRGKPYGAKAAPYGFLLPAAVLFALFFALPIGYALW
                     LSLHKAEVRGLGLGKGARAEVWAGLQNYTAALTDPELGHAALRVFGYGAIVVPVMLGLA
                     LLFALLLDTERVRARSFSRLAIFLPYAIPGVIAALLWGFLYLPDVSPFHHLLGKLGLPQ
                     PDLLDGGPLFASLANIAVWGGTGFNMIVIYTSLRSIPVEVYEAARLDGATPVQIALRIK
                     IPMVAPSLVLTFFFSVIATLQVFGEPTTLRPLTNSIPTTWSPLMKVYNDAFLGGNVYAA
                     SATAVVLAAASFVLSFALLKVSNSLTKHRGNR"
     gene            complement(21331..22641)
                     /locus_tag="G412_RS0118170"
     CDS             complement(21331..22641)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004922228.1"
                     /locus_tag="G412_RS0118170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_028813319.1"
                     /transl_table=11
                     /translation="MSHTLHRRLAATATAVALGATALTACGSSGGDDQADSGPVSLTYW
                     AWAPGMDKVADLWNKKNPDIKVTVKKQAAGDDLVAKIITASKAHQAPDLVQAEYQALPT
                     LVSNDALADISREIGDTEKEFAPGVWQQTTLGTDAVYAVPQDSGPMMFYYREDLFKQYG
                     LSAPTTWDDFAKTARALKKKAPDKALTTFSSNDSGLFAGLAQQAGAQWWTVDGDKWKVG
                     IDDPATRKVADFWGGLVKEGAVDNQPMYTPAWNKALNTGKQIAWVSAVWAPGTLTTAAP
                     ETKGKWAMAPLPQWTKGDNATGSWGGSTTAVTTDSRHKAAAAKFATWLNTDPQALAALV
                     KESGIYPAATAAQTSGALAEAPDFFANQPDFYMRAAAIAKTTAPASWGPNVNVAYTAFK
                     DKFAHAAKTRSGFGAALTAMRDATVADLKKQGFEVAP"
     gene            22853..24874
                     /locus_tag="G412_RS0118175"
     CDS             22853..24874
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982763.1"
                     /locus_tag="G412_RS0118175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-galactosidase"
                     /protein_id="WP_028813320.1"
                     /transl_table=11
                     /translation="MPDTAPHGLHGLAFGGDYNPEQWPESVWQEDVRLMGEAGVTMVSV
                     GIFSWALLEPEPGTYDFGWLDRVIDLLHAHGIRVDLGTPTVVPPAWFYRAHPDALPVSR
                     EGVRYAFGSRGAICHSSPAYREAAARITTELARRYAAHPALAMWHVHNEYGVPVSACYC
                     DTCAAHFRRWLDARYGSVEGVNEAWGTAFWGQHYTAYDQIDPPRTAPTTGNPAQQLDYR
                     RFADATMRENFVSERDILHRLSPGIPVTTNFMTALSQCDSVDYWAWGREVDVVTNDHYL
                     ITDGRRTHVNLAMAADLTRSVAGGASWLLLEHSTSGVSWQPRNPAKRPGEMARNSLAHV
                     ARGSEGAMFFQWRQSRRGAEKFHSSMLPHAGTDSRIWREVVRLGADIGSLAAIRGTRTV
                     PDVAMVWDWASWWAQSLEWRPSQDHDARERADSFYETLYDRHLTVDFAHPEADLSAYPL
                     VVVPALYLATEAAGNNLRRYVENGGTLVVSYFSGIVDEHDAVHPGACPGALRDVLGLTV
                     EEWSPLGEGESVRIAGPRDTSLTADVWTEFVVPRGAQTVWTYADGPAAGGPAVTRHRLG
                     EGTAWYVSSRLGAVALDPILGAACEDAGIAPRTELARDVEVVRRRGDGGEYLFAINHTE
                     HDTKVPLDTPGTELLTGEHTAGHLPVPAGAVRAVRLHT"
     gene            24939..26507
                     /locus_tag="G412_RS0118180"
     CDS             24939..26507
                     /GO_function="GO:0015926 - glucosidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381489.1"
                     /locus_tag="G412_RS0118180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="WP_037649149.1"
                     /transl_table=11
                     /translation="MYVRPRGTFRTLLRAAALPVLGALLVTALPGRQAHAASTLTNPGF
                     ESGTSSWFTYSATGQDSASYAEPGGHGGSSRLAHWSSTAYKVETYQYLSGLANGSYTLS
                     AWVRSSGGQNAAYLALRNCGSAEQRTDLPPTPNGKWIRLVTSVKVTGGQCTVSVNSDGR
                     AGNWLNVDDLTFTPGSTGLAVKGADVSMLKKSEDFGGVYRTSGGTTGDGLAVLKSAGAN
                     YGRLKVWVDPADGYSDKARVLQMAQRIKAQGMKLLVDFHYSDIWADPGAQTKPAAWASH
                     SYSRLTTDVYDHTYDVLNALKAQGTTADMVQIGNEINTGLLWPEGSTDNWDQTAGLLKS
                     GINAARAVSPTTRIALHLAHGGDNSLYRWWFDNAKARGVNFDVIALSFYGYWHGPLSDL
                     QANLDDISARYGKSVMVAETAYPFRLDSKDSHENIIDLTSELVAGYPASTAGQAAWLRD
                     VMNVVEAVPGGRGLGVIYWDPTWTAVTGNGWDPADPSSGNGWENQALFDYDNRLLPAAN
                     WFSHR"
     gene            26580..27836
                     /locus_tag="G412_RS0118185"
     CDS             26580..27836
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180902.1"
                     /locus_tag="G412_RS0118185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_028813322.1"
                     /transl_table=11
                     /translation="MTEHSTRLEPPRAPGVSRDAPLFSTAAVAASCVGFVLIGALQALY
                     GPAIPAFRAEFGLSPSAAGLGLSAHFIGGVAGVLLFDRFFGRTGNRRLLGASYLLMALG
                     AAGFALAPNWPLGLAMALVAGLGFGGIDYGLNQLFAIGFGRRSTAMLNILNAHFGIGAI
                     LGPVLIGAVGAEHYPAVFLAFAVANLPLLLCLRGVRGQAPKAPAEGTGQAGAGGQAGAG
                     GQVLGRSLGTLIAVFVALYVLHVGIEAGVGGWEPTHLETVGYGAGFAATATSVYWLMMT
                     AGRFLVAPLALRFRAQTIITVSCAGMTVCLLLASVPGLAPYAYAGVGLFIAPIFPTGLP
                     WLNQAAPQARRAGAIVIAASMAGGVAAGPALGKAIEWSGVRSVPLVLSVVSALCLASAL
                     WLVRATRRTTSPPRSAGST"
     misc_feature    28132..28145
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.23"
                     /tool="antismash"
     misc_feature    complement(28133..28146)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.27"
                     /tool="antismash"
     misc_feature    complement(28164..28176)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(28164..28179)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
ORIGIN
        1 ggacgcccgg cgggggccca acctcggttc ccgctgggcc agttacgtcc tgcgccaccc
       61 cgtcgccgta ctgctcctgg ccgtcctcgg cctcggcgcg gtcgccgtgc ccgccgccag
      121 tctggagctc ggcttgcccg gcgagggcac catggcgccc gacaccaccc agcgcaaggc
      181 ctacgacatg ctctcggagt ccttcggcgc cgggttcaac gggccgctga tgatcaccgt
      241 ggagggccag gacgcggcgg ccgccgccaa gagggtcggc gagcggctgg ccgagcggga
      301 cggcgtcgcc gccgtcaccc cggccacgcc caacgaggcc ggcgacaccg cgatcctcag
      361 cgtcgtcccg acgaccggtc ccaccgacga cggcaccgag gacctggtcc gctcgatccg
      421 cgccctcgcc gacggcttcc gagccgacac cggtgcggag gtgcttgtca ccggccagac
      481 cgcgatgttc atcgacttct cgcagaccct ggacgacgcg ctgcttccct atctcgccct
      541 ggtcgtcggc ctggcgtttc tgctgctgat ggtggtcttc cgctcggtcc tcgtcccgct
      601 caaggcggct ctgggcttcc tgctctccgt ggcggcggcg ctcggcgcgg tggtggcggt
      661 cttccagtgg ggctggctcg ccgatgtctt cggcgtcgac cagccgagcc cgatcatgag
      721 cacgatgccg atcttcatga tcggtgtggt cttcggcctc gccatggact acgaggtgtt
      781 cctggtgacc cgcatgcggg aggcgtacgt ccacggggcg cgccccgccg aggccgtagt
      841 caccgggttc cgctacggcg gccgggtggt cgccgcggcc gccgccatca tgatcagcgt
      901 gttctccggc ttcatcgtgg aggacaacga cttcatcaag atgatcggct tcggcctcgc
      961 ggtcgcggtg ctcttcgacg ccgtcatcgt ccgcatgacg atcgtgcccg ccctgttcgc
     1021 cctgctcggc gagggcgcct ggtggctgcc gcgctggctc gaccggctgc ttccccacct
     1081 cgacgtcgag ggcgagaagc tctcccgcat ggctccggcc cagcgggtgg cacctgcgcg
     1141 ccgcgaacat gaactagtcg actaggcaac cgggttgacc gtggtcaggc ccagcggctc
     1201 ggcgccgctg ggcctgccgt gtgcggcgac cgcgtacctg cgtctaccgg gcccttgccg
     1261 tcggtcagca gggtgatggg ctctcttgtg gttactcgga agctgtagga gagtggccgc
     1321 tgacctgaca gaacgcactt ttcggtggct gaggaacctt atggtgacca agcagttcac
     1381 gggcgcgccc gaggaagcgg acctgaggcg cgcggactct ctggcgcggg agatcttctc
     1441 ggatgtcgcc aacaagtggg cgttcctgat catcgagtct ctcggtgaag gcaccctgcg
     1501 cttcagcgag ttgcggaacg atgtcgaggg catcagccac aagatgctta cccagaacct
     1561 gcgcatgctg gagcgttacg gcctggtcga acgcaaggtg caccccaccg tgccgccgcg
     1621 agtcgagtac acgctcaccg agccgggcca agccctgcga gccacagtcg acggaatgtg
     1681 cggctggacc caccagtacc tcggtcacat cgaggcctcc cgccgccgct tcgacgcctg
     1741 acgtgcgggc agcactgccg gcgtccggat gcgatgcgta cggtggcctg gcctgccgta
     1801 tgacggtgat ccggcttgag ggccccttgc tcgcgtggtg ggtcgggcgc aagctggtct
     1861 tatggctgcg cacgacggcc ctacgctcat cacttccgta cagagagcct tccgtctgct
     1921 ggaagcggtg agtgcgcacg agagcggcgc gccggcgaag cagttggcgc gtgagacggg
     1981 cctgcctctg gccaccgcct atcacctgtt gcggacactg gctcacgacg ggtacgtacg
     2041 gaagctggac gacggcgggt tcgtcatcgg ggatcagttg gacgcgctgc gtgccggagg
     2101 tcgcgtgcag acgctgctca gccgtatccg ccccgcactg gccgctttgc gggacgacct
     2161 gtcggccgcc gcgtacctga ccttctacga ggagggcgag atccgaatcg ccgagatcgt
     2221 cgacagtccc cgggcacagc gggtcgatct ctgggtggga ttcgaggacg ccgggcatgc
     2281 caccgcgctg ggcaagtgcg tgctgcgcga gatggacgag gagtcccgca acgactacct
     2341 ttcccggcac tccctcgaag atctcacgcc ccggaccatc acccaccgtt ccgagctgat
     2401 ccggcggctc gaatcgtcga ccaccgaccc ggctgtcacg gacctggagg agtactccct
     2461 cggtacggtc tgcatggcgg tgcccgtata cagcggcggc gttctcggct cgctcggtgt
     2521 gtccatgcgg gcggaccggc tctcccgcct cgacgaggtg cgagcgcgtc tgctgccgac
     2581 agccagtcgc gtgaccaggg gtctttcgct cactatctga aatttccgtc cttgtggcgc
     2641 ccgcacggac cctgttctct ggacgaaagg gacattcggg aggatgcgcc gccacgagga
     2701 gaggactgcg gaccacaaca tgagtcaagc ccgagaccat ggagccggct ggtggccgac
     2761 gggaacgctc acatggaccc ggaccggagc cggcccgcag ttcgcggccg gcactcccgt
     2821 gctgatcgtc tttgtcgttg tactcctcga cctcgtcagc ggagctggga tggtctggct
     2881 gccgctgctc gccgccggtc ccgcgctggc cgccgccacc actcggctgc cgggggttct
     2941 gtgcgtcggc ttcctcgctg ccgttctggg cgcggtgctc ggcattcgag acggtgtacc
     3001 gggtcgcgag ctggcgatcg tgctctcggc gctggtcgct gtgacgctgg ccagtggcct
     3061 ggccagcggg ctgcgcgtgc gccgtgagcg ggtgctcgcg gccgtgcgct cggtcgccga
     3121 ggccgcccag cacgccctcc tgaagcccgt gcccgcgacg gtcggccagt tccaggtggc
     3181 cgtccgctac agcgccgccg aggcggaggc ccgtatcggc ggggacctct atgcgctggt
     3241 gccgacgccg tacggggtca ggctgatcgt cggcgatgtg cggggcaagg ggctgcccgc
     3301 ggtgggcacc gccgctctgg tgctgggtgt cttccgtgag gcggcctacg acgagcctga
     3361 cctcctcgac gtcgtcggca ggatcgagcg aagcctggcg cgcaatctgg gttccgacga
     3421 cttcgtgacc gccgtggtcg ccggatatcc cggcgcaggg agcatggagg tggtcaactg
     3481 tgggcacgct ccgccgctga tggtccgcga ttccgacgtc ctggttgtcg agccgaccca
     3541 tccggctccc ccgctcgggt tgcgtgctct taccggcgag agtccgagcc ttcagatact
     3601 gcccttcgcc gacggtgacc agctgctcct ctacaccgat ggtgttaccg aggcccgcaa
     3661 ccacgcccgt gagttctacc cgctggtcga gcgggtggcg cggcacctgt ccgacgagcc
     3721 gtcccgcact ctcgccgcgc tccacgacga gctgctggcg cacgtcggcg gtcggctcca
     3781 cgacgacgcg gcgctgctcc tgctccggaa accggccgct gtcggctcgg cggcatccgc
     3841 tgcctaaagg aggtcccgta actgatcttg ggggcgatgg cggaaggggt gatcggggcg
     3901 cggtcggctc gtttatccgg taagggtgag gttgtacagg cgggcgacgc agagcatgtc
     3961 gtggtggacg ccgtcgcctt tcaggcggca gtcgcggagg atcgtccagc ccttcatacg
     4021 ggcgaaggtg tgctcgacgc gctcctgaac tcgcttgtag tggcgccagt tgggttggtc
     4081 cgccagtacg cgccgaccag cagcacacgg tccgccagcg gcagcctcca cggccgtccg
     4141 cgacccgggg cgtcggcacc ctccctacgc agctgagtca ccagcttgct caaggcgcgc
     4201 gggctcagcc cagtgagcgg ggctgtccag gacggctccg ctgccgtgat cacaccagcc
     4261 atccggagat catttcagtt gccgacaccc ctcccatgac tgatcctggg ctccgagcaa
     4321 gcaaggggga caagatgggc ctgatgctct tcccaggcga cgaggacgtg gcgagcccgg
     4381 acatctcctg gtcctacacc ggcttcagca tgttcaggaa gtggttggcc caggccgagg
     4441 ggttcacgct cgccgagatg gacggcttcg gcggagatcg ccagtggtgc agcgtctcca
     4501 ccacgctggc gccactactc aatcatccag acgacggtgg cccccacctc gcgcccgctc
     4561 aatgcgcggc catgttgccc cgactggaag caatactcga ccaacatcag cctgacgaca
     4621 gcgaccccgc cctccgacgg cgcatcgaag acgtcagtca gttggtcacc gtcctgcggt
     4681 tctgcgtgga caaggacgtt gagctcatct tcggctaacc acgggagcgc ggagtgaccc
     4741 gtcgttgagg ggatggcctg cggttacggg acagccttca gagcggggcg atgccggcgc
     4801 cgagctgagt tgcgaacagc ggggcatagc gcaccatgag agggtctgaa gccaaggccg
     4861 tcgtactgca gccacggtga aataccaggc gcgagggccg cggggtcgcc gcgcgtcatt
     4921 cggacgccgc tatgaccttg cgtacgttct ccaggcttcc gcacccctcc ttgagcagcc
     4981 gctcgcgctc gcgggcgaac gcctcgccca gctcggcccg acggtcgtcc gcgacgagtt
     5041 ccctggcgtg attgaggagc gtacgttcct cctcgtccag atgatgggtg atggcctcgg
     5101 acagctcctc cagcttctcg tcccagtcct ccgaacccac ttcgggcacc tccaggagag
     5161 ctgccagggc cttgttgccc tccgtgtgtt cctcttcgcc gtggtcgacc tcgtcgttgt
     5221 cgaccttccg gtagcggcgc agcgccgggt agacctccgc ctcctcggcc tcaccatggg
     5281 cgatcagcag gtccgcgaac tccctgagcg cggcggcccg gtcctcctcc acgctccgca
     5341 tcgcgcggaa gaggtcctcc atccgccggt ggtcctgcgt gatcagctcc accacgtcgg
     5401 tcacgtcgcc tcctgagttg tgcgagtacg tagatcgaac gccttccccg taatccgcac
     5461 gtcatcccct gacgggacgc tgagcgggag ggactggcgg tacccgccgg gaggttgagt
     5521 tcaggtcgaa tggtgctcgg tcgggccgat ggcagcgtgg cgcggcatcg cacgtcatga
     5581 acgaagccgt gttgccgcgg tgaagggctt ccaccgcggc gaaccggcca atcaggggcg
     5641 gttccacgct gtcggcttga cccgctgcca gaccagccag ccaagcgctt ggtggccagc
     5701 ggcattcggg tggtacgact ccaccagggg gttactgaac ccgttgatcc actcgggatc
     5761 ctcacagatg gcgtggccct tgaacgacgg ctcgacttcg gcgaagtcaa attcatgctt
     5821 gccggcctcg atccgcagca cgtcattgag cgtgtgggcc gctccattca tctcggtgcg
     5881 aacgtcgttg ggaagcccgc cgtcacccag gcaggtcggg ttgaatgtgg gagtgaccaa
     5941 cttcgggtag ccgaccacga cgaccttggc gttcttggcc ttcaacccga tcttgtcgta
     6001 gagcttgtcg agccttccag gaaggacgtt caagtactgc tgctggatcc acctcaggtc
     6061 gtccatgcac gggcgtccga gcaccgcgca ctcgagcagc acatccgcga agccgaagtc
     6121 gttggctccg acctgcacgg tgaccagctt ggttctcttg ctcagcgtcc gggtctggtt
     6181 gttcctcacg ccactgacgg tggcgccgca gtacgcctgg aagtccagct gggcgccgag
     6241 cgcggcggcg acccgacgcg ggtacgcctt ggttgagttt ggaacccgga tcttcgcctc
     6301 ctcgttgatc cagcagttgt gggagtttgc cgtcggagat cccgcaccga tgcctgccgc
     6361 caccgagtcg cccagcgcga cgtacttcat cggccgggga gggccggcac cctgggctgt
     6421 ccccgctcca gctaccgcca ttgcccccgc cagcgccagg gctgtgatgc gtagtgcgct
     6481 cctggttttg cccatcgttt ccgtccccct ttggctgcct gcgctcggcg tacagccccg
     6541 attgtctgcg ccggggccag tggctcctcc ggcgttttcg gcacacttga gcctgcgccc
     6601 tggagcttgg ggaaaccttg aatgaaattc caacgccgag cccaagctcc aagcgcccac
     6661 gcagatttgc tgtgatgggc agcccccatg cgcacgcgcg gctagaggct gggtcagctg
     6721 aaatgtcaac aggcgcttac gagcgtcggc gagtaggccg acacggcgcc gcagggcggc
     6781 acttgtactc cttgaacgct cccggcatct gtgcccgcag ctctcgtctg cccaggcctc
     6841 ccggcaccag gggcgcccgt ccgcatcccc cggtttgtac gttgtaatga acttgtaatg
     6901 cccacgcccg tccttggcat gctcagaggc cgtacgctcc gtaagccctc gctccacagt
     6961 ttcaacagct gcaacgcgag gcgacacact catcacttcc ctgctcccgt ggggtggctc
     7021 agccagaacg ggcagcagga agcacagcaa gcaagtgggg aatttgatgt ccaccgacgt
     7081 ccgcacgtcc gcgcccgccg gcgctccttc cagcccggtt gtcacctggc tgctcaccct
     7141 ggtgaccctg ggtatctact ggctcgtctg gtactacaag gtcaacaagc aggtgaaggc
     7201 gatcgacccg accattgagg tcaagcccgg catggcggtc gttgccgtca ccctcggctc
     7261 gttgctgatc atcccgccgt tcgtctcgat cgtgaagacc ggctcccgca tcgcccaggc
     7321 acagcgtgcc gccggcgtga cctccgacta ctgctccggc atcgtcggtc tgctgctcgc
     7381 cttcgtcctc ggcctgaccc cgctctacta ccagagcaag ctcaacacgg tctgggccga
     7441 ccgcgcctga tttaccgcca cacacgcggg tcttacacgc gggtagggga cggaagagcg
     7501 atttgctctt ccggccccta cccgcttcgc gtccccgccg gaccggcgag ccagagacga
     7561 tcccgcccct tgtggccggc gcgcctttgc cgaacggccg cgtgccgtgg aacgcgaatg
     7621 cgccagggcc ggcggccggt acggtgtccg gctgctcgtc gtcgccacgc gtccaggccc
     7681 agccacatca cgccagtggg cgagcggcac gactccgctg ggcgtctgcg gcgtgcgtcc
     7741 gcgtccgccg cgagccggct cgggcggccg caatccgcgc cgggcgagtc cgtagcggaa
     7801 acaggaccgg tcgcgccggt ggagagccgc aaacggtggc ggccaccgga tcggcgtacc
     7861 gcgcttttcg atcagcgact cccggcactg ttccggcgaa ttgatcgcga atgatgatgt
     7921 cgcggcggtg ccatattcgg ccccttcgcc tattgcgccc caggtgctca atgccgctca
     7981 atgctgctca aagcctgccc gttccagcca gtcgggccat ggccgaaagg gcctcttatc
     8041 ggtgtcgccg gcatctgctt cagtgaggtc tgttgcgcgc ccgacaaatt ggaggaggct
     8101 ccatggctga agtgagaaaa gtggtcaggc ccgcggtgac cgcgtcgtcc cggccctgcg
     8161 cgttcgtatc gcccgacaag ggcaacgctc cgacgatcac cccggtgcgg aaggacgtac
     8221 aggctgcccc tgccgctgct gagcagcgga aacaggacac gcctgcctga gccccgacgc
     8281 acctcctggc ccccgccgga gacggctggg tcctcttacg ccgcaggcgg ggcacaccac
     8341 gcgccccgcc tgcggtggcc gattgttccg atgccttgtc ggacgctccg atacgcaggg
     8401 agaggcccgt ccatgccgaa ttcgatctat cagtcctcgc tttacgtccg tacgctgcgt
     8461 tctgccgaag atcgtgattt caccgctttc ggcggccgtc tcggtacgta tgacggaagc
     8521 gaacgcacca tggccttcca ttccctgtac ggaaatgcac ggctggtcga ccgggacatt
     8581 gtagagctgc tcaaggacgc ggcgaacggt atgacgccgg agcagttgct ggaaaggatc
     8641 gacgaggctt cgcttcgcga tctcatcgag gcgcgctatc tggtggaggc cggccgtgac
     8701 gaggccgagg agatcaacgc gctgctggag agccggcagg ccgtgctcag cagcggggtc
     8761 ttccactcct ccatccagct cgtactgacg aacgcctgca acttctcctg tcagggctgc
     8821 ttcgcctaca acttcgacgg cggtgtggag gagcggaaca cctcgggcga gaccgtgaag
     8881 cccggccccg ttctcgtcga gctgcgccgg tcgcggccgg actccgggcc gacgctggcc
     8941 aaaggcgact ggaaccacgg ttccgactcc gggcgcaacc cgtcgatgca catgtccctg
     9001 gacgtggcgg agaagaccgt caaggaggcc atcgccctgc gcaaggccaa tggcggcggg
     9061 cacctgaccg tctccttctt cggcggtgag ccgacgctcg cgcggggcac catcctgcac
     9121 gtactgcgca ccttcgggga cagttacgac ggcgtctccc tctcgtacga cctgacgagc
     9181 aacggctcgc gcatcgacga cgagctgctg gccgcgctgg cccgccacaa ggtggacacc
     9241 accgtctcca tcgactacct ggtgccggag acgggcgagt tccggggcgg acagcagcag
     9301 cggaccgcct ggcccgtggt gcgcaaggcc attgtggaca tgaaggccgc cggggtgccg
     9361 gtcagcatca ccaccgtgct gtcccagttc acctgggaca agtggggtac tccgctcatc
     9421 gacttcgtcg ccgaggccgg cctggactcg ctcgatgtga tcgtgtcctt ccaggccaag
     9481 gagttcttcg accggcacag tccgcacgat gtggcgcagc ggctgctgca cgcggtcgac
     9541 tacggccgcg agcgcggcgt acagctcagc gggtactggt accagacgtt ccagatgatc
     9601 atcgacgagc gcaagtgggc cgcgcaggcc gactacaaga cctgcccggc ggtgggccgc
     9661 cagctgtcca tcgagccgaa cggcagcgtc ttcgcctgca aggccaccgc ccgcaagctc
     9721 ggcaccatcg acgactggca gggcatcttc gcctccgacg cctaccagga ctacggcatg
     9781 cgcgcgtaca ccaacggccc cggctgccag ggctgcgagc tgcagggcac gtgctcgggc
     9841 ggttcggcgg gggcgctgga ggaggagaac gggtcgatcc agctgatgtc tcccggctac
     9901 tgcgcctaca tgcgcgaagt ggtccagggg ctgctggaac ggcaccacgc ccagaccgcc
     9961 gccttcgcct gacgcccccg agagagagcg gtacggtttc gtggcaacga tcggaatgca
    10021 cttcggccat gacgcgggcg ccgccctgac ccaggcgtcg ggttaccacg tcatcgaagc
    10081 ggaacggcgc ctgggcctgc gccacgtgtg cggcggcaac gagcagttcg cgcggaccgc
    10141 cgccgactgg ctggccgagc tacgggacag agccgagtca ccggtgaccc gtgtggccgt
    10201 ggccgactgg tacacgccgg tgtgccgcgt gctgcccccg gcgctggtcg agctggtcgg
    10261 caaggacgcc tggtgggcgc ggcccggcgg aaacctcctc aacgccgtag tccgcccggt
    10321 ggacctcgcc ggctggccac tggcggagtg tctggggcag gtcgagctga ccgtggtacg
    10381 ccaccactac gcgcacgccg cgctcgccta ctacacgtcg ggggcccgca aagccctggt
    10441 gatcgccctg gacggcaccg gcaactacgc cgagaacggc atggtctgcc tcggcgaggg
    10501 cgaccggctg acccccgtgc tgtccttcac caaccggtcg tgcccgcgct tcggcctcgt
    10561 ctacgaggcc ctggcccggc gcgtccacgg cagccagttc gacaccggca agctgctggg
    10621 actgtcggcg acgggcgaac cggaccccgc gctgctcccg gtactgcgcg ccatgctcgt
    10681 accccagggg gcgcgaaccc gctcaccgga cctgtacgag cccctggacg aggacatgct
    10741 ggccgggacg gccctgcgct atgccgacag ctcgtgggag tacgacccgg acagcggggg
    10801 ctacctcgac gccggactgg cggattcctc ggacgacgat gtcgtgcact cctacggctc
    10861 ggtgttcccc gacgagatcc gtaccgcgga cggccgccgg accgaggtgg ggagcagccc
    10921 cggcgaccgc gtctgccggg acctggccgc aacgctccag gcggccgtcg aacgcgacct
    10981 ggtgaacctg gtcaccggca tcagcgcgcg cttccccggc tactccacgc tctgctacgc
    11041 gggcggctgc gcgctcaaca tcaccgcgaa cagcgccctg gtggagtcgg gacagttcac
    11101 ccgggtccac atccccacgt gctgcgacga ttccggtatc gcgctcggcg ccgccctggc
    11161 cgccgccgat cccgcgcagc gcccggcccc ggcggccggc ccgccggggg cgcacctggt
    11221 ctacgcgggc gccccgttgg cggtcgccga ggacggggcg cggaactcgg cgctgcgggc
    11281 ggggcgcgcc gtacggacct gggccacagc ggtggcgttc accgaggcgg tggcggaact
    11341 gctggccggc cgcgggtgcg tggcctggct ggagggcggc atggagaccg ggccgcgcgc
    11401 cctcgggcac cgttccttgc tcgtctcggc gcactggtcc ggggcgcggc agtacgtctc
    11461 tcagacgatc aaggggcggg agtggttccg cccggtcgcc ccgctgtgtc ccgcggagga
    11521 tgccgaacgg tacttcaccg gccccctcga ccacaccgac accatgctgt tcgccgtacg
    11581 cgtcaaactc gaacgggccg agcttctcgg cgaggtgcgg cacatcgacg ggaccgcgcg
    11641 gctccagacg gtacggcccg cctctcatcc cgcactgcac gggctctgcc gggccgtcgg
    11701 cgcccgtacc ggtctgcccg tgctgatcaa cacgagcgcc aacggcggtg gccgccccat
    11761 cctcaaccac ctcgatgacg ccctggagct gctggccggc accgcactgg acgccgtcgt
    11821 cctgccggaa cagcggctgg tcatcgagtg agccgagtga gccgagtgag aaccccgcgc
    11881 ggggagttgt tgtccgaaag cgagctggtg aacccctcca ccgtattcga ccatgtgagg
    11941 gcgcttcacc cgtcggaggt gcgtcggtga acacagtcca gctgagggac atacacaaat
    12001 cgctgaacct gcgggtgctg tccccgcagg actgggacca atggaccacc gagggttatg
    12061 tggtggtgcg ggaaacggtg cccgagcgca acgtcacccg gctcaccgag gcactgtggg
    12121 acttccagga catgcggccg gacgacccgt ccacctggtc ctccgcccac accggcaacg
    12181 agcggcttcc cggacacagc ggcctcgtcg agatgtacaa ccaccaggcg cagtgggaca
    12241 accggcagac gcggcgggtc tacgacgcct tcgtcgacat ctgggaccgt acggacctgt
    12301 gggtgacgat cgacttcgcc aacgtcaatc cgcccaacca cggctcccgc gcgttcgcgg
    12361 gtttcgtcca ctgggacgtg gacacctcgg tcgatcccct cccggtgagc tgccaggcgg
    12421 tgctgtccct gaccgagggc aacgaggaca tcggcggctt ccagtgcgta ccggagatct
    12481 tcaccgagtg ggacacctgg gtgaagggcc agcccgagga ccgcgacccc tataccccgg
    12541 acatcaccgg ctacggcatc accacccccc gcgtgcatcc gggcgacctg atcatcttca
    12601 acagcctgct gccacacggg gtgcatccga acgtctcccg tgaccaggtg cggatggccc
    12661 agtacatctc catggccccg gcctgggaag agaacgaggc gctgcgggag gcgcgtgtcc
    12721 ggttctggcg ggaccgtgtg ccaccgcacc ctccggaggg cggactgcgc aaggaggagc
    12781 acaccctgta cggacccgcc gagctgaccc cgctcggtga acggttgctg gggctgcgga
    12841 gctggcatga gtgaccggcg cccccagccc gtgctgcctg gggcccgccg gcctgtgccc
    12901 gtagcccgtc ggcacgcggg gagagggctt ggctagcgcc acccctggga cgtccgccgc
    12961 ccggccgggt ctcggcgggc cgtttcggtg gctgtgggtg tccaccgccg cgtcgaacgc
    13021 gggcgacggc gtcacccgca cactgctgcc cctgctggtc gtcgccagcc acccggagcc
    13081 cgcggcggtg gccgggctga cggcggtcaa catgctgccc tggctgctgt tcgccctgcc
    13141 cgccggggtg ctggtggacc gtctggaccg ccggcgcatc gtgctgtgga gcaatctgct
    13201 gcgcggcgcc gtgctgctgg gcgcgatggc ggtactcgcc ggagaccgtc cactcgccgt
    13261 cctgtacgtg ctcgcgttcg tcctgggcat tgccgagacc ctggccgaca ccgcggcgcc
    13321 cgcgatgctt ccgcgcatcg tcggacagcg ggatctggag cgggccaacg gccggctgtc
    13381 cgccgcgcag atcgttttca acgacatggc gggcccgccg gtcgccggcc tgctggtcgg
    13441 cgtggccgcc acggcggcgc tggccaccgg cggtgtgctg tacgccatgg ccgccgtcct
    13501 gctgctgggg ctggtgaccg tggagcggga ccgggccggg caggcgacca gcgggcccgc
    13561 ggagcccgta cgcacgggaa tccgggccgg gttgcgcttc gtcctcggcc accgcacgct
    13621 ccggctgacg ctggcggcca gcgcgctgta cgggctcgtc ttctccgcca ccttctccat
    13681 gctcgtactg ctcagccacc ggacgctgaa actggacgcc accggctacg ggctgctgct
    13741 gacggccggc tccctgggcg cggtgggcgg cagctggctc gcgccgaaac tggcggagcg
    13801 gctgcccgtg gtccggctgg cccgctggtg tctggtcgcc tcgggactcg cgtacgctgc
    13861 tctgggcctg gcccgcactc cggcgcaggc cgccgtcgcg ctgctgtgca acggcgtgtt
    13921 catgatgggt tggaacatcc ccgtcatgtc cctgcggcag cggctgacgc ccgaggagtt
    13981 ccagggccgc gtgatgagcg tgtcccggct ctgtgcctgg ggcgccatgc ccgtcggtgc
    14041 gagcctcggc ggactgctgg ccgaggccct gtccgtaccg gccgtcttcg tcatctgcgg
    14101 tggtgtcctg gccgcgggtg cgctgctgct gctcgcgccg ctgcgtgcgg acggttacga
    14161 cggcccggct gtgcaggccg ggccgcaccc acggcagaac tccgatccct cgacgaagga
    14221 gtgaaccttg accgcagagc cctacgacac cgtgatcgtc ggaggcggac ccgccggcct
    14281 gaacgccgcc ctctacctgg gccgttcatg ccgccgcgtg ctgctcgtcg actccggtga
    14341 cgcgcgcaac atggcggccg gcgtcatgca caacgtcctc accaatgacg gggtggacat
    14401 caccgacttc cgcgccaggg cccgagccga actgggcgcg tacgacgtgg cgttccggga
    14461 cgacgaggtg gtctcggtgg agcccgacgg tgatcacgtg gtgacgacca ccaaggagtc
    14521 cggcaccttc cgcagccgca ccctgctcta cgcggccggc gtgcgctccg agctgcctcc
    14581 ggttccgggc ctggccggtc tgtggggcac ttcggtgttc gagtgtccgt actgccacgc
    14641 ctgggaagta cgcggcacat ccttcggcgt gtacggcggt gtcgtccccg gtgagtgcct
    14701 ggcggccacc ctgaccgtct ggtccgactc cgtcacctac ctgtccgacc gcagggagct
    14761 gcccgaggac gagcgggagc ggctgacggc ggcgggcatc cccaccgtca ccgacaagat
    14821 cgcgcgggtc tcggcgcacc cggagggagt ggccgtggag ctggcggacg gccggtcgct
    14881 gaccttcggc gcgctgttcc tccacatgga caccgagccg cgcgtggaac ccctgcgccc
    14941 ctggctgcgg agcgacgacc tggagtccgt acagaccgac gagcgcgggc gcacccggct
    15001 cccccgactt tacgtggcgg gggacctcgg caagaacatg cagcaggccg ccatggccgc
    15061 ggccagtgga ggtctggcgg ccatggccat caacgcggac ctcatacggg aggaccgccc
    15121 cggttccctc cccgctccgc cgcccgctcc ggcgccgtaa cgccccccgc gtccaccgac
    15181 cggcaccagg gacgggagac ccgccaccgt gcaatcaccc cgagcgcaac tcgccccgca
    15241 gatggagcac tacacctttg tcctggagga ccagccgtac ctgggcttct tccagtacgg
    15301 caacgagaac acgccggtct acagcaccga cgagcacggt ttccgcgtca cccgtggccc
    15361 gggtgacgcg gcggcgaccg tctcgggcga acggccgccc ggcccggtac ggctgctcgc
    15421 gggcagctcg gcgacgttcg gcgtcggggc caccggcgac gccgccaccg tgccctcgcg
    15481 gctgtggacg cggcacgcgc cccggctccc ctggctcaac ttctcgggtc agagccacaa
    15541 ctccgcgcag gagctgatgc tcctcaccct gttccggcac cacctgcccg aggtggcgga
    15601 catcgtgctg ttctccggtg tcaacaacct ggtgctgagc aggctgccga cggagcagca
    15661 gggccgtcac ggcgcgttct tcgagtgcgg cgccgccccc gacaccgtac ccacgcccga
    15721 ggaacggatc gaccgggccg ccggtctcac cgtgcggcac ctcagtacgt ggaaactgct
    15781 cgccactgcc atgggcgcac gactgacgtt cgtgctccag ccactcgccc cctgggtgcg
    15841 ggacgaaccc accccgcagg agaagctgct cttcgacgag ctggacgacg tctccaactt
    15901 ccgccggctg cacaacgaca tctccaccat ggaggtgggc cggaagtacg ccgaggtgat
    15961 cggcgccggg tgcgccgggc tggacgtgcc cttcctggac atgaacgccg cgctggcgga
    16021 ggcgaccacg cccgacgagt ggctgttcat cgaccgggtg cactgcaccg acctgggcta
    16081 cgacaccgtc gcccggctgc tcgccgggca tctcgacctc acctgaggag ccacccatgt
    16141 ccgtgatccg gcgactcctg ggcaggctgc ggcgccggcc gcccaccgcg gcccggccgc
    16201 ccgagcgctc ccgtacccct cgccaggacc accaggaccg ccggtcgggg ctgcggcccc
    16261 agtccgagga cgacgcgtcc atctacccgc tcttctgatc gcggccgcgg ccgcggccgt
    16321 cgccactgga ccgaggcgta cgaggaacgg gaacgggagg gcaccgatgc cggaactgat
    16381 cctgggcatc tccgcgtact accacgacag cgcggcggcc gtcgtggcgg acggcgtccc
    16441 gctggccgcg gcccaggagg aacgcttcag ccgccgccgt cacgaccccc gcttcccggc
    16501 cggggccgtc gactactgtc tcagggccgc cggggcgaag ctcggcgaca tcgccgccgt
    16561 cgccttctac gaggactccg ccctgaagtt ccggcgggcc ctcgccacct ggctggccac
    16621 cgcgccccgc ggctttccgg cgttccacga cgccttcccg cagtggctgg cctggaagcg
    16681 gaacgccacc ggggaggtac ggcgcaacct gcgggcgcgg gcgggcgacg gcggcgccct
    16741 gccgcccgtc gtgagcgggc ggcaccacgc ctcgcacgcg gcttccgcgt tctaccccag
    16801 cccgtacgag tcggcggccg tactgtgcgt cgacggggtc ggcgagtggg cgacgaccag
    16861 catgtggcac ggccggggaa cgcggctcag cgcgctgggc gagctgcgct tcccgcactc
    16921 actgggcctg ttgtactcgg cgttcaccta cttctgtggc ttcaaggtcg actccggcga
    16981 gtacaaactc atggggctcg cgccgtacgg gaaaccccgc tacgcccagc tcatccgcga
    17041 acggctcatc gacatcaagc cggacggctc gttccgcctc gatctgcggc acttcagcta
    17101 tgtgtacggc cgggtcatga ccggacgcgg cttcgaggag ctgttcgacg ggccgcgccg
    17161 ggagcccgag ggcccgctca ccgagcgcga gttcgacctc gcggcctccg tccagcaggt
    17221 caccgaagag gtgatgctgc ggctcgccag gacggtgtgc gagcgcaccg gggaacggcg
    17281 cctgtgcctg gccggcgggg tggccctcaa ctgcgtggcc aacggcagga tcgtggcgga
    17341 gggcctctgc gacgaggtgt gggtccagcc cgcggccggt gacgcgggcg gcgcactggg
    17401 cgccgccctg gccgagtccc accggcgcgg tgcgcctcgc gcgcacgtcg gccggcgcac
    17461 cgacgccatg tcgggagcgc tgctcgggcc cgcttacgcc gccgaggaga tcgcggggtt
    17521 cctcgaccgc cacggcgtcc cgtacacccg cctgtccggg gaccggctgg cccggcgggt
    17581 ggcggcggag atcgccgccg ggcggatcgt cggctggttc cagggccgca tggagttcgg
    17641 cccgcgggcg ctgggggccc gttcgatcct cgccgacccg cgcgatcccg gcatgcagtc
    17701 cacgctgaac ctcaggatca agttccggga gtccttccgc cccttcgccc ccgcggtgct
    17761 cagcgaggac gccgcgcggt ggttcgacct ccgccaggag agcccgtaca tgctgctgac
    17821 cgctcaggtc gcggccgaac agtgccgtga cggtgacggt gacggcgacg gcgacggcgc
    17881 tgacgccggc gcgggcgatg acctgacggg gctcggcctg ctccgggtcc ggaggtccac
    17941 gattccggcg gtcacccacg tcgaccggtc ctcccgcgtg cagacggtgg gcccgcacga
    18001 caacccgccc ttccgccggc tcctcaccgc cttccgggac ctgaccggct gccccctgct
    18061 ggtcaacacc tcgttcaacg tccgtggcga gcccatcgtc aacacgcccc aggaggcgta
    18121 cacatgcttc atgcgcaccg ggatcgacct gctggtactc ggcgacttcc tcctggagaa
    18181 gcaggaccag ccgccgtggc gggacaagga ggacgactgg cgtgacgcga tcccgatgga
    18241 ctgacctcgc gcgccggccg gcgctcgccg ccctctactt cctcgtactc acgcccatcg
    18301 gcctgtgcgt acgacggatc cgcgaccccc tgcgacgctc ctggcacgcc tgcgccacca
    18361 cgtactggga ccacccctga acctgccccg gccccggggg gggaccgggt gccggccggc
    18421 ccgcgcggag gcgcggtcag gccgatccgc ggcgtaccag ctcggtgggg aggatgacgg
    18481 cggaaggttc ctcccccgcg atccgggcga gcagcatccg taccatttcg gtgctgatcc
    18541 ggtcccacgg ctgacggacc gtggtgaggc cgggccgcgt cgacagggcg gccggcgagt
    18601 cgtcgaagcc gcccaccgcc acatcttccg gcacccggcg cccgccccgg ctcagggtgt
    18661 cgagtacccc ttgggccatc aggtccgatg ccacgaacac cgcgtccatg tcgggcgccc
    18721 gttcgaggag cagttcggct gccgcctcgc cgctcgcccg gctgtagtcg cccggcacga
    18781 tgagcgactc gtcgacgggc agaccgcatt cggccagtac gtcgcggtag ccggcgagcc
    18841 gctcgacacc gccgggagtg tccgcggggc cggtcaccgt ggcgatgcgg cggcgccccg
    18901 aatcgtggag gtagcgcacc atcgaccggg cgccgtcccg gtcgtccgcc gcgacgtaac
    18961 tgacccgcgc acgctgcccg agcggcttgc cgcaggcgac cacggggacg ctcgccgcgt
    19021 cgagttcgct cacgaccggg tctccggagt ggctggagac gagcagtacg ccgtcgacgt
    19081 gcccgccttc gatgtagcgc aggttgcgcc gtcgctcggc ctcggttccc gcgatcatga
    19141 gcagcaacgg gatgtcccgg gcggcgagcg cctgtgtgca ggcccgcagc agcacattga
    19201 agttggggtc ctcgaagaag cgctcctgtg gttcggtcag caggaacgcc accgagtcgg
    19261 acttgccggt gatcagcgag cgggcgtgcc ggttgacgac gtaacccgtc ttgcggatgg
    19321 cggcgttgac ggccgcctgc gccgccgggc tgacatagtg cccgccgttg agtacgcgcg
    19381 agacggtgcc gcgcgagacg cccgcctcac gcgccacgtc gtggatcgtc accgatcgcc
    19441 gcttgccgtc tgtaccgcgg atcatgaatt tttcccctcg ttccctgcgg tcaggacttt
    19501 acggctccgg agagcaggtc gaggctccag aaccgttgga cgacgaggaa cagggcaatg
    19561 agcggaacga tggccagcag ggcgccggtg atcaccagcg tgtagagggc cggggtgttc
    19621 gagccctggg agagcagggt gaacagtccc accgtcatgg ggaacttctc gtcgtcgccg
    19681 agcatgatga acggcagcag gaagttgttc cagatcgcga cgaactggaa gaggaagatc
    19741 gtcaccaggc cgggcgacat catcgggacg gcgatccgca ggaagatccg ccattcgccg
    19801 gcgccgtcca cccggcccgc ctcgacgagt tccgtgggga tcgcggcccc ggcgtagatc
    19861 ctgccgaggt agacaccgta cggggaaagg atcagcggca gcagtacgga caggtacgag
    19921 tccgtcatgc cggccttggc catcagcagg tactggggga tggcgaggat gaccgggggc
    19981 atgagtacgc ccgccaggat cacgttgaac acggcttccc ggccgcggaa gcggtagagg
    20041 gccagcgcgt agcccgagag ggcggagacg atcgtggaca gcagggcgcc gaggcccgcg
    20101 tagagggcgg agttggccat ccagcgccag tagatgccgt cgcggtacgc gcccaggtcc
    20161 gcgaggttgt cggcgaagcc ggtgccgggc aggaaggtga aggtggagaa cagctccgtg
    20221 ccggacttgg tcgaggccac cagcacccag gcgacgggca gcaggcagta gagggcgccg
    20281 agcagcaggg ccgccgtggg caggagggcg gtccggcggg gacccggcgg gccctgggag
    20341 gtgccgggcg tggtgccggg cgccggggcc gccttgagga gcgtgctcat cggtttcctc
    20401 ggtgcttcgt aagggagttg gagaccttca gcagggcgaa ggagaggacg aaggaggcgg
    20461 cggcgaggac gactgcggtg gccgaggcgg cgtacacgtt tccgcccagg aaggcgtcgt
    20521 tgtagacctt catcagcggg ctccaggtgg tcgggatgct gttggtcagc ggcctgagcg
    20581 ttgtcggctc gccgaagacc tggagtgtgg cgatcaccga gaagaagaag gtcagcacca
    20641 gggagggcgc caccatgggg attttgatac gcagggcgat ctgtacgggc gtcgcgccgt
    20701 cgagcctggc cgcctcgtag acctcgacgg gaatggagcg cagcgaggtg tagatcacga
    20761 tcatgttgaa gccggtgccg ccccagacgg cgatgttggc gagggacgcg aagagcggtc
    20821 cgccgtcgag caggtccggc tgcggaagcc ccagcttgcc gaggaggtgg tggaaggggc
    20881 tgacgtccgg caggtagagg aagccccaga gcagggcggc gatcacgccg gggatggcgt
    20941 acgggaggaa gatcgcgagc cgggagaagg agcgggcgcg gacccgctcg gtgtccagga
    21001 gcagggcgaa cagcagcgcc aggccgagca tgacggggac gacgatcgcg ccgtaaccga
    21061 acacccgcag ggcggcgtgg ccgagttcgg ggtccgtgag agcggcggtg tagttctgca
    21121 ggcccgccca tacctcggca cgggcgccct tgccgagtcc caggccccgc acctcggcct
    21181 tgtggaggct gagccagagc gcgtacccga tgggcagggc gaagaagagc gcgaagagga
    21241 cggcggccgg gaggaggaag ccgtacgggg ccgccttggc cccgtacggc ttgccgcgac
    21301 cgcgcgcctt gcggcgggtg gcggtcatgg tcacggagcg acctcgaagc cctgcttctt
    21361 caggtccgcg acggtggcgt cccgcatggc ggtgagggcc gcgccgaagc ccgacctggt
    21421 cttggcggcg tgggcgaact tgtccttgaa ggcggtgtag gcgacgttga cgttggggcc
    21481 ccaggaggcg ggggcggtgg tcttcgctat ggcggcggcg cgcatgtaga agtcgggctg
    21541 gttggcgaag aagtcggggg cctcggccag tgcgccgctg gtctgggcgg cggtggcggc
    21601 cgggtagatg ccgctctcct tgaccagcgc ggccagcgcc tgcgggtcgg tgttcagcca
    21661 ggtcgcgaac ttcgcggcgg ccgccttgtg ccgggagtcg gtggtgaccg cggtggtgga
    21721 gccgccccag ctgccggtgg cgttgtcacc cttggtccac tgcgggagcg gcgccatcgc
    21781 ccacttgccc ttggtttcgg gcgcggcggt ggtcagggtg ccgggcgccc agacggcgct
    21841 cacccaggcg atctgcttgc cggtgttcag ggccttgttc caggcggggg tgtacatcgg
    21901 ctggttgtcg acggcgccct ccttgacgag accgccccag aagtcggcga ccttgcgggt
    21961 cgccgggtcg tcgatgccga ccttccactt gtcgccgtcg acggtccacc actgggcgcc
    22021 ggcctgctgg gcgagcccgg cgaacaggcc cgagtcgttg gaggagaagg tggtcagcgc
    22081 cttgtccggg gccttcttct tcagcgcgcg ggcggtcttg gcgaagtcgt cccaggtggt
    22141 gggggcgctg agtccgtact gcttgaacag gtcttcccgg tagtagaaca tcatcggccc
    22201 ggagtcctgc ggcaccgcgt agacggcgtc ggtaccgagg gtggtctgct gccagacgcc
    22261 cggcgcgaac tccttctccg tgtcgccgat ttccctggag atgtcggcga gggcgtcgtt
    22321 gctgacgagc gtcggcagcg cctggtactc ggcctggacg aggtcggggg cctggtgggc
    22381 cttggacgcg gtgatgatct tggctaccag gtcgtcaccg gccgcctgct tcttcacggt
    22441 gaccttgatg tccgggttct tcttgttcca gaggtctgcc accttgtcca tgccgggcgc
    22501 ccaggcccag tacgtcagcg agacgggccc ggaatcggcc tgatcgtcac cgccggacga
    22561 tccgcaggcg gtgagcgcgg tcgcgccgag tgcgacagcg gtggcggtgg ccgcgaggcg
    22621 gcggtggagc gtgtgggaca tggggcaact cttcctgacc gaagggacct ccctgttcat
    22681 cggggaggtc ggccctgcat ctgtgagcgt tcacagtaga gaaacgttcc agacacttgt
    22741 caatggttgt tcgtgtgcgg ttatgttgca ctaccgcatc gatcaacgcg tgtgcacgtt
    22801 cccagatcat cacgatccaa cgtctcaaac tcccacgtct caggagagat tcatgccgga
    22861 cactgctccc catggcctgc acgggctcgc cttcggcggg gactacaacc ccgaacagtg
    22921 gccggaaagc gtctggcagg aggatgtccg gctgatgggc gaggccggcg tcacgatggt
    22981 gagcgtcggc atcttctcct gggccctgct cgaacctgag cccggcacct acgacttcgg
    23041 ctggctcgac cgggtcatcg atctgctcca cgcgcacggc atccgggtcg acctcggtac
    23101 gcccacggtg gtcccgcccg cgtggttcta ccgcgcccac cccgacgccc tgcccgtcag
    23161 ccgtgagggc gtgcggtacg cgttcggctc acgcggcgcg atctgccaca gctcccccgc
    23221 ctaccgcgag gccgccgcac ggatcaccac cgagctcgcc cggcggtacg ccgcacaccc
    23281 cgccctcgcg atgtggcacg tccacaacga gtacggcgtt ccggtcagcg cctgctactg
    23341 cgacacctgc gccgcacact tccgccgctg gctggatgcc cgctacggct ccgtcgaggg
    23401 ggtcaacgag gcctggggca ccgccttctg gggccagcac tacaccgcgt acgaccagat
    23461 cgacccgccg cgcaccgccc cgaccaccgg caatccggcg cagcagctcg actaccgccg
    23521 cttcgccgac gccaccatgc gggagaactt cgtatccgag cgggacatcc tgcaccggct
    23581 ttcccccggc atccccgtca ccaccaactt catgacggcc ctcagccagt gcgactccgt
    23641 cgactactgg gcctggggcc gcgaggtcga cgtcgtcacc aacgaccact acctgatcac
    23701 cgacggacgg cgcacccacg tcaacctcgc catggccgcc gacctgaccc gctccgtcgc
    23761 tggcggcgcc tcctggctgc tgctcgaaca ctccaccagc ggtgtcagct ggcagccccg
    23821 caaccccgcc aagcgccccg gtgagatggc ccgcaactcc ctggcccacg tggcccgtgg
    23881 ctccgagggc gccatgttct tccagtggcg ccagtcccgg cgaggcgccg agaagttcca
    23941 ctcgtcgatg ctgccgcacg ccggcaccga ctcgcggatc tggcgcgagg tggtccggct
    24001 gggcgccgac atcggctcgc tggccgcgat ccgcggtacc cgtaccgttc cggacgtggc
    24061 catggtgtgg gactgggcat cctggtgggc gcagagcctg gagtggcgtc ccagccagga
    24121 ccatgacgcc cgcgagcgcg cggacagctt ctacgagacg ctctacgacc gtcacctgac
    24181 cgtcgacttc gcccaccccg aggccgacct gtcggcttat ccgctggtcg tcgtgccggc
    24241 gctctacctc gccaccgagg ccgccgggaa caacctccgt cgctacgtcg agaacggcgg
    24301 caccctggtc gtctcctact tctccggcat cgtcgacgag cacgacgccg tgcaccccgg
    24361 cgcctgcccg ggtgcgctgc gcgacgtact cggcctgacc gtcgaggagt ggtcaccgct
    24421 cggtgagggg gagtcggtac ggatcgccgg cccccgtgac acatcgctca cggccgatgt
    24481 gtggaccgag ttcgtggtgc cgcgcggggc gcagaccgta tggacgtacg ccgacggacc
    24541 ggccgccggc ggccccgccg tcacgcgtca ccgcctgggc gagggcaccg cctggtacgt
    24601 ctcctcccgg ctcggcgccg tcgcgctgga cccgattctc ggcgccgcct gcgaggacgc
    24661 cggcatcgcg ccccgcaccg agctggcccg cgacgtcgag gtggtacgcc gccgcggtga
    24721 cggcggcgag tacctcttcg ccatcaacca cacggagcac gacaccaagg tgccgctgga
    24781 cacgcccggc accgaactgc tcaccggaga acacaccgcg ggccacctgc ccgtaccggc
    24841 gggcgccgtc agggccgtac ggcttcacac ctgacctgcc cccgaacgaa ccgcaccgtc
    24901 tcccccgccc gcccgccacc gtcgaaggga cctcgacgat gtacgtacga ccaagaggca
    24961 cattccgcac cctgctcaga gccgccgccc tgcccgtgct cggcgccctg ctggtcaccg
    25021 ccctgcccgg ccggcaggca cacgccgcgt ccacgctcac caaccccggc ttcgaatcgg
    25081 gtacttcgag ctggtttacc tactccgcca ccggtcagga ttccgcctcg tacgccgaac
    25141 cgggcggaca cggcggcagc agccgcctgg cccactggtc gtccaccgcc tacaaggtgg
    25201 agacgtacca gtacctgtcc gggctggcca acggcagtta cacgctcagc gcgtgggtgc
    25261 ggtccagcgg cggccagaat gccgcgtacc tcgctcttcg caactgcggc agcgccgaac
    25321 agcgcaccga tctgcccccc acccccaacg gcaagtggat acgcctcgtc acctcggtca
    25381 aggtgaccgg cggacagtgc acggtcagcg tcaactccga cggcagggcc gggaactggc
    25441 tgaacgtcga cgatctcacc ttcacgccgg gctcgaccgg gctcgcggtg aagggcgccg
    25501 atgtctccat gctcaagaag agcgaggact tcggcggcgt ctaccgcacc agcggcggca
    25561 ccaccggcga cggcctcgcc gtcctgaagt ccgccggcgc caactacggc cggctcaagg
    25621 tctgggtgga cccggccgac ggttacagcg acaaggcccg cgtcctgcag atggcccagc
    25681 gcatcaaggc ccagggaatg aagctgctgg tcgacttcca ctactccgac atctgggccg
    25741 acccgggcgc ccagaccaag ccggccgcct gggcctcgca ctcctacagc cggctgacga
    25801 cggacgtgta cgaccacacg tacgacgtcc tgaacgccct caaagcgcag ggcaccaccg
    25861 ccgacatggt gcagatcggc aacgagatca acaccggcct gctctggccc gagggctcca
    25921 cggacaactg ggaccagacc gccgggctgc tcaagtccgg gatcaacgcg gccagggcgg
    25981 tctcaccgac gacccggatc gccctccatc tggcgcacgg cggcgacaac agcctgtacc
    26041 gctggtggtt cgacaacgcg aaggcgcggg gcgtgaactt cgacgtcatc gccctgtcct
    26101 tctacggcta ctggcacggg cccctgtccg acctccaggc caacctcgac gacatctccg
    26161 cccgctacgg caagtccgtc atggtcgccg agaccgcgta ccccttccgg ctggacagca
    26221 aggacagtca cgagaacatc atcgacctca cgagtgaact ggtcgccggt tacccggcga
    26281 gcaccgccgg gcaggcggcc tggctgcgcg acgtgatgaa cgtcgtcgaa gccgtgccgg
    26341 gcggccgcgg gctgggcgtc atctactggg acccgacctg gaccgccgtc accggcaacg
    26401 gctgggatcc ggccgacccc tcctccggca acggctggga gaaccaggcg ctgttcgact
    26461 acgacaacag gctgctgccc gcggcgaact ggttcagcca ccgctgacgc catcagcgcg
    26521 gcgcgcggga accgtcatgt ccttcgccca cgcatgcgtg ggccgtcagc ggagtccata
    26581 tgaccgaaca ttccacccgg ctggagcccc cgagggcgcc gggcgtctcc cgtgacgctc
    26641 ccctcttcag tacggccgcc gtggccgcct cctgcgtggg ctttgtcctc atcggtgcac
    26701 tccaggctct gtacggaccc gcgatcccgg cgttccgtgc ggagttcggc ctctccccct
    26761 cggccgccgg tctcggactg agcgcgcatt tcatcggcgg tgtggccggt gtgctgctct
    26821 tcgaccggtt cttcggccgg accggcaacc ggcggctcct cggcgcctcc tacctgctga
    26881 tggcgctcgg ggccgcgggc ttcgccctgg cgccgaactg gccgctgggc ctcgccatgg
    26941 cgctggtcgc cgggctgggc ttcggcggga tcgactacgg actcaaccag ctgttcgcga
    27001 tcggcttcgg ccgccgctcg accgcgatgc tgaacatcct caacgcccac ttcggcatcg
    27061 gcgccatcct cggcccggtg ctgatcggcg cggtcggtgc ggagcactac ccagccgtct
    27121 tcctcgcctt cgctgtcgcc aacctgccgc tgctgctgtg tctgagaggt gtacgcggcc
    27181 aagcaccgaa ggcccccgcc gaaggcaccg ggcaggccgg agccggcgga caggccggag
    27241 ccggcgggca ggtgctgggc cgcagcctgg gcaccctcat cgcggtcttc gtcgcgctct
    27301 acgtcctgca tgtgggcatc gaggcgggcg tcggcggctg ggagcccacc cacctggaga
    27361 cggtcggtta cggcgcgggg ttcgccgcca ccgccacctc ggtctactgg ttgatgatga
    27421 ccgccggccg gttcctggtc gcgcccctcg ccctgcggtt ccgggcgcag acgatcatca
    27481 cggtctcgtg cgcgggcatg acggtatgcc tcctgctcgc ctcggttccg gggctcgccc
    27541 cgtacgcgta cgccggcgtc ggcctgttca tcgcaccgat cttccccacc gggctgccgt
    27601 ggctgaacca ggcggcgccg caggcgcgca gagccggggc gatcgtcatc gccgcgtcca
    27661 tggccggcgg tgtcgccgcc gggcccgctc tcggcaaggc catcgagtgg tccggcgtcc
    27721 gctccgtccc actcgtgctg tccgtcgtct cggcactgtg cctggcgtcg gcactctggc
    27781 tggtccgcgc cacacgccgc accaccagcc caccgcgctc ggcgggatcc acgtaaaagc
    27841 cacaacacag ccgcgtccgc cgagccgcgg ttgcgttcgt atgcggacgg gcagtgatgt
    27901 ggccatgatc aatactgcgc tgcccatccc caccgctgcg ggcgggctcc cggtcctcgg
    27961 ccacgcgata ccgctcatgc gcgacaacct gcgcttcatc gcctcgctgc gcgactacgg
    28021 ccccctggtc aagatctacc ttcagcccgg acagccgacg atcgtcgtca accgcccgga
    28081 cctcatccgc aagatgctgg tggacctcgc ccccaacctg gacaagggcc gcttcttcga
    28141 gaaaatgggc caggttctcg gcggtgacag cgtcgtcacc gccgcgggcg ccgcacacgt
    28201 ccgtgcccgg cgccagttgc agcccgcctt ccggcacacg gaga
//
