LOCUS       NZ_CP011664            21038 bp    DNA     linear   CON 03-MAR-2024
DEFINITION  Streptomyces sp. Mg1 chromosome 1, complete sequence.
ACCESSION   NZ_CP011664
VERSION     NZ_CP011664.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. Mg1
  ORGANISM  Streptomyces sp. Mg1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     De Novo Assembly of the Streptomyces sp. Strain Mg1 Genome Using
            PacBio Single-Molecule Sequencing
  JOURNAL   Genome Announc 1 (4), e00535-13 (2013)
   PUBMED   23908282
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUN-2015) Biochemistry and Biophysics, Texas A&M
            University, 300 Olsen Blvd., College Station, TX 77845, USA
REFERENCE   3  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JUN-2013) Biochemistry and Biophysics, Texas A&M
            University, 2128 TAMU, College Station, TX 77843, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 8.2
            Genome Coverage                   :: 30X PacBio; 80X Illumina
            Sequencing Technology             :: PacBio + Illumina MiSeq/HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 08:10:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,822
            CDSs (total)                      :: 7,726
            Genes (coding)                    :: 7,467
            CDSs (with protein)               :: 7,467
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 260
            CDSs (without protein)            :: 259
            Pseudo Genes (ambiguous residues) :: 0 of 260
            Pseudo Genes (frameshifted)       :: 109 of 260
            Pseudo Genes (incomplete)         :: 200 of 260
            Pseudo Genes (internal stop)      :: 18 of 260
            Pseudo Genes (multiple problems)  :: 60 of 260
            CRISPR Arrays                     :: 11
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:43:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7293752
            Orig. end                         :: 7314790
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011664.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Paul Straight
            (paul_straight@tamu.edu).
            Annotation modified by the submitter.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21038
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="26"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21038
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21038
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11038](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11038)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(1931..2431)
                     /locus_tag="M444_RS31580"
                     /old_locus_tag="M444_31565"
     CDS             complement(1931..2431)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018554807.1"
                     /locus_tag="M444_RS31580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31565"
                     /product="hypothetical protein"
                     /protein_id="WP_235441296.1"
                     /transl_table=11
                     /translation="MRIPRLPAVTALVAAVVLVGSTAASALGPTAEQRLDGTIVVAGNT
                     CGWTNARTSADPPNALSVDRTSINTPGGNLSCAGGITATLNNNPAFTFDDTAGTAKADL
                     IDITGKMSFISCRYKAANTVWNRDGATRKYVNQAFTAVKTSGSFLCPGSVTTAAGDASM
                     LFH"
     misc_feature    complement(2526..2540)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     gene            complement(2554..3207)
                     /locus_tag="M444_RS31585"
                     /old_locus_tag="M444_31570"
     CDS             complement(2554..3207)
                     /GO_function="GO:0004062 - aryl sulfotransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025627.4"
                     /locus_tag="M444_RS31585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31570"
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="WP_008742340.1"
                     /transl_table=11
                     /translation="MIHGDVVYELTWDGEVVWRWAAIEHLNPEQVPLNRHFAREHWPMA
                     NTVGELADGGVVVGFRSASTTVAVDRADGSVRWRIGPDAHSQQHYPHELPGGNILVFDN
                     GTYRDTTSVPYSRVLEIDPRTGEEVWSYEDNPPQNFYSPYMSSAQRLPGGNTFIAEGSF
                     GRLFEVTPDGDVVWEYVVPEFGSFGRGVGLESSRGAQNSVFRAYRYAAEEIPWL"
     misc_feature    3279..3294
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            3469..4044
                     /locus_tag="M444_RS31590"
                     /old_locus_tag="M444_31575"
     CDS             3469..4044
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238000.1"
                     /locus_tag="M444_RS31590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31575"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_050779382.1"
                     /transl_table=11
                     /translation="MSRPEPTPEAVEVGRVIRAWRKRRGISMASLAAGSGLSQPFLSQL
                     ERGLATPSLSSIYRIAEALDVTPGTFLRPPDRPGAVSHESDPQVIRVSEAAGQVARVLI
                     PGGRSGLMEAYEHHFEPGRGERGWFEHPGEDFLYVLEGEVVLEVEGEEPLTLRAGQSAH
                     HRGDVPHRCRLPGPSAAAARTLLVTANG"
     gene            complement(4061..5443)
                     /locus_tag="M444_RS31595"
                     /old_locus_tag="M444_31580"
     CDS             complement(4061..5443)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020665702.1"
                     /locus_tag="M444_RS31595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31580"
                     /product="hypothetical protein"
                     /protein_id="WP_037794014.1"
                     /transl_table=11
                     /translation="MLARRLLLPGLITLALTATGCSSATHSGAADPAAPATLAPAADGT
                     QQLDVAAAPQGSPTPTAVARVGSGKGAPEKSSLKVASYDQATGRAVISSAPQRATPSPG
                     RSPAAEKPVVVGDVIASAPAPGAPNGLLAKVTEVGKKTDSGTEVKTAPTTLSSVLNDDK
                     ADGKVPVDPASVAVEPLMKGVTFSWAKSQGVRFGPQGAKLPLGNLRLDVDVPVETAPGA
                     PVSAGASVSGFVQLAPTVEFSYDGSGGAGPRTAFLGMSGDWASQWNLKGHAAASTGAPK
                     RIPFAKLHSAPVIQVGPVPVVVNLDLTVYVQVEADGRVTLDVRQEVKGDFRVGGSYATG
                     KGWNPVSTSNVQSTPVKAEVTAAGQVKGALGAEASVGLYGAVGVSADFAPYLRGEADVK
                     ASASSDGKASVSGAWAVYGGFDLSGQLHLQLSLFGTPILERRVPLGALHREWPLASGKA
                     AL"
     misc_feature    5476..5493
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.51"
                     /tool="antismash"
     gene            complement(5593..5994)
                     /locus_tag="M444_RS44155"
     CDS             complement(5593..5994)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M444_RS44155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_324615602.1"
                     /transl_table=11
                     /translation="MNHLEQSPAACELAHALIDHGTALHTIGDPHRAAQQLYRGMEAAS
                     ACGASGLVSRARSQLASAGLRPRRLHASEQDTLTLAEHAAATRASVGLDNAAIAAELRT
                     DAQAVSELLSAVFTKLGTDRLGLRRAMEG"
     gene            complement(5909..8410)
                     /locus_tag="M444_RS31600"
                     /old_locus_tag="M444_31585"
     CDS             complement(5909..8410)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="M444_RS31600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31585"
                     /product="AAA family ATPase"
                     /protein_id="WP_324615603.1"
                     /transl_table=11
                     /translation="MDELCGTPDSSQPSRRGGVLTFAGSAGIGKTSLLTEARRHAAERH
                     CTVLFARGGEQERQVPFHVMRQLIQPAFAAMTEDERRDVLGTWYGIVAPALGLTAAPEG
                     LTAPDPQGVRDGLDWVVTHLTVRSAPVVLVLDDAHWADAESLAWLTAFAARAEELAMLI
                     MVACRPDEIPADAGSLRALIKRQGTRPHELAPLTTSAVARIVRDALGDNADDVFCRECW
                     AITGGNPFEVVELAMKGRDRGLKPHQDSIPQLRDLASAVKGSGLIDRLEQLGTSTVRLA
                     WAAAVLGTAVPISIVGGVAALGEAQAADAIAQLRDARILTVLTSLRRQEVVEFFHPLIA
                     TAVYRSIPPGVRVAMHGMAAQALVDDGFGAAAAARHLLEMHPEGDPWVVQQLRQAARDS
                     FSAGAPDAARRYLARALREPPDAEYRAEVLFELGSANLLHDPATTINQLRAALEEPKAD
                     QELREAITYRLAQAMAHTGQLAEAAGLLSDEAKLATSSRTRLRMQAEQFKWNSVRMDEA
                     NSPARSRLLAQFAKRLTGRGVPERHILGLRAWDAAMRGEPAATALEYAEQALDGGMNWT
                     DQDFGFEVPAVVAVTLMYCDQPGRAEELFNAGIMEFESKGWRGAHLSFVYTLLGYVRFR
                     RGRLAEAEDFVRNGLQIAERVGHDIPGAVVRGGHAHRDAAGPGQYGGGAAGRPRVQAGG
                     GLPAGGRLPRSAGGVGQAPAGAGADRRGKAAPLRGGQAAGSAGNAQSVLESLAARPGPR
                     PDREGARAGACHGGRGGGPGPGVRDVERDRARPARVGGDPGRVPGDGLVAGGGEPPRTV
                     PGRLRTRPCADRSRYGPAHHR"
     gene            complement(8637..9986)
                     /locus_tag="M444_RS31605"
                     /old_locus_tag="M444_31590"
     CDS             complement(8637..9986)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010474928.1"
                     /locus_tag="M444_RS31605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31590"
                     /product="cytochrome P450"
                     /protein_id="WP_008742345.1"
                     /sec_met_domain="p450 (E-value: 1.1e-81, bitscore: 273.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARTERSGLAKSAPVAPGRLPLLGHALPLWREPIAFLESLRQYGD
                     VVRLDIGTWPVHMLTNPDHVHAVLVQQAQKFGRGRIFDRLRPMFGNGIVTTDGDFHRKQ
                     RRMIQPAFHRSHIAEYAEVMGRAAEEMTGSWTAGSEISMVTEARRYALSSVAEMIFSGD
                     LSRPAIAEVHRSLPIVLEGMLLRAVMPKSLDRLPVPLNRRFDAAAARLRAIIDQVIAQY
                     GDTQEGGSDLLSLLLSSVDAETGERMDAAQVRDEVIAIMFAGTETSATTLAWIFHELGR
                     HPEAEKRLHAEIDAVVGKRPVRIGDIPQLTYTNNVFQEALRMHSPLLFTRQALVPLTLG
                     GVSIPAGAELAYSPYALHRDPALFRDPGVFDPDRWQQEAQDRRRAHQYIPFGAGQHKCI
                     GDTFAVAEILTAVATVASRWRLVPAPGVTVRELPAGMPQPSELPMIPVAR"
     misc_feature    complement(9927..9929)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..11038)
                     /locus_tag="M444_RS31610"
                     /old_locus_tag="M444_31595"
     CDS             complement(10001..11038)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010474899.1"
                     /locus_tag="M444_RS31610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31595"
                     /product="terpene synthase family protein"
                     /protein_id="WP_008742346.1"
                     /sec_met_domain="T1TS (E-value: 6.3e-62, bitscore: 209.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLHSFTVPDFHLPFGNSKHPQAARANTEATSWVLRHELVTHAA
                     EEFSGIGCGHLAGRVSGDVPYDRILLLAEWMAWSFVLDDQHDHLIRTGQVAAWRPVIGA
                     ITEYLETGKAGDASARQNPLVAGFMDLCDRILAGMSQGTAARYRTHVPLMLGSLDQEAG
                     NRRAAERPALQDYILMRRHSSQILPMMDMVEAGLGIDLPQHIHDLPEFRAVVDSALDVI
                     SWGNDVFSLPKEYSCGDNNNLVSLVATWEGRSLPDAVQAVEGRIQARIEEYLESERRLL
                     RLMEARPDTDPSVRTAVTRCVRSYQDWIIGADLWQRYECTRYSDERFAAGLESAYTRPD
                     LISVA"
     misc_feature    11261..11275
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.79"
                     /tool="antismash"
     misc_feature    11288..11302
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.21"
                     /tool="antismash"
     misc_feature    complement(11385..11399)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     gene            11462..11821
                     /locus_tag="M444_RS31615"
                     /old_locus_tag="M444_31600"
     CDS             11462..11821
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M444_RS31615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M444_31600"
                     /product="hypothetical protein"
                     /protein_id="WP_124290556.1"
                     /transl_table=11
                     /translation="MTDHHPAGPGDGQDVDVLGPYLEVLRARLTGERFEVLIRAVQTTC
                     ALLAEDQETVLKVPAATELAPDLQREYLSLMAVMITGHLDHRLVEIAAPDGGRGWAVVD
                     NTRPYPARPADVRSS"
     misc_feature    11534..11536
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11808..14006)
                     /gene="helR"
                     /locus_tag="M444_RS31620"
                     /old_locus_tag="M444_31605"
     CDS             complement(11808..14006)
                     /codon_start=1
                     /gene="helR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010038080.1"
                     /locus_tag="M444_RS31620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31605"
                     /product="RNA polymerase recycling motor ATPase HelR"
                     /protein_id="WP_008742348.1"
                     /transl_table=11
                     /translation="MNPVTTSAFGLPERLSAKADPSLIGGDERHFAAIAQSLDEAIAEL
                     SDRLAELRGAPGGLGREAMERDAEIHRLTARLRTLRRFGLDLCLGRVVGADDPEPLYVG
                     RLGLTDGEGRRLLIDWRSPAAEPFFAATHANPMGLAGRRRYRWAGGRVNDYWDEVFTTD
                     GFEGHAALDDQSAFIAALGGSRSARMRDVLGTLQADQDAIIRADSRGALVVDGGPGTGK
                     TVVALHRSAYLLYSDPRLGHRRGGVLFVGPHEPYLGYVADVLPSLGEEGVQTCTLRDLV
                     AEGASAAPESDPEVARLKSSADMVRAIEKAVAFYEEPPAEGMTVSTAWGDVRVSPDDWA
                     EAFGAPGPGSPHNEAREQIWEELATILMDKQGMDEEEDGISHAAFLRSLRQDAELVTAF
                     TRAWPLLEPADLVSDLWTVPAYLRMCAPWLGRDEVAKLRREAAPQAWTVSDLPLLDAAR
                     QRLGDPGAARRRRRHDAAVAAERERMSRVIEEIVSVADIDSAGDDSEGAVRMLRGRDLQ
                     DSLIDEGALPTAAPDRLAGPFAHVVVDEAQELTDAEWQMLLLRCPSRSFTIVGDRAQAR
                     QGFTESWTERLERVGIDRIELASLSINYRTPREVMAEAEPVIRAALPDANVPVSIRSGG
                     VPVVHGCVCDLDDVLDTWLAGHEAGTACVIGSPGGAAGAFRARPRVRSLTPELSKGLEF
                     DLVVLVDPEEFGEGSPGAVDRYVAMTRATRQLVVLTSS"
     misc_feature    14072..14086
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.09"
                     /tool="antismash"
     gene            complement(14370..14606)
                     /locus_tag="M444_RS31625"
                     /old_locus_tag="M444_31610"
     CDS             complement(14370..14606)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115476.1"
                     /locus_tag="M444_RS31625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31610"
                     /product="chaplin"
                     /protein_id="WP_037794002.1"
                     /transl_table=11
                     /translation="MKIRTLAAAACLIAGAVLGGAGSAVADSEAHGIAAGSPGVLSGNL
                     IQVPIHIPVNACGNSVNIIGLLNPTAGNVCVND"
     misc_feature    14646..14660
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.63"
                     /tool="antismash"
     gene            14832..15302
                     /locus_tag="M444_RS31630"
                     /old_locus_tag="M444_31615"
     CDS             14832..15302
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890974.1"
                     /locus_tag="M444_RS31630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31615"
                     /product="hypothetical protein"
                     /protein_id="WP_008742350.1"
                     /transl_table=11
                     /translation="MNNVRKRAGITAGVVLAGIGLAFPAVAFAEDHSKPATAAEARPHA
                     GKGAELREEHRKELAEALAKDLGVPVDKVTGSLEKFRAAQGEKHREERKDRKDERAGER
                     PDAAALQKKLADRLDQAVKDGKLTRAQADAVIAAAKAGVLPGPGGGPHHQER"
     misc_feature    complement(15373..15388)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.08"
                     /tool="antismash"
     misc_feature    complement(15420..15433)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.84"
                     /tool="antismash"
     gene            15425..15580
                     /locus_tag="M444_RS42575"
     CDS             15425..15580
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152392.1"
                     /locus_tag="M444_RS42575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6131 family protein"
                     /protein_id="WP_008742351.1"
                     /transl_table=11
                     /translation="MIILGVILLIIGFVTGLSILWTIGAILVVVGLVLWLLGALGHAVG
                     GRNHYW"
     misc_feature    complement(15679..15694)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.34"
                     /tool="antismash"
     gene            15770..16231
                     /locus_tag="M444_RS31635"
                     /old_locus_tag="M444_31620"
     CDS             15770..16231
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145939.1"
                     /locus_tag="M444_RS31635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31620"
                     /product="hypothetical protein"
                     /protein_id="WP_037794003.1"
                     /transl_table=11
                     /translation="MRRTLTKAGSLAAVSLFALALAAPAQAAQDSAAAARPAATKAVYF
                     EFTDGRNTFVIQLTDAAKIRQARDVINGVDTENISVMGKIVKTPASYNKPWKYTLAPSS
                     VKFFSMATEVCDASISYVNEHLDEVGGALLPNSTWCPWQSKLTREIPAP"
     gene            16341..18116
                     /locus_tag="M444_RS31640"
                     /old_locus_tag="M444_31625"
     CDS             16341..18116
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.4"
                     /locus_tag="M444_RS31640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31625"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_053065834.1"
                     /transl_table=11
                     /translation="MAETERGCPLAEGVRFRLLGPMTARTADGAALALGPNQQRALLAV
                     LLLRAGRPVPVPELCDALWGERPPARAVGTVRTYASRLRALFEPDRPARAPARILVFAS
                     GGYALRLSRPAVDIDEFERGLTDAARLRTAGAVRQAYRTRERALALWAGCPLAGLPGPH
                     AEARRDRLTGLWLTAREAHFHDALELGLDRETPAVPALRAFAAEHPLREGAQELLMRAL
                     HRAGRTGEALAVYEATRETLALELGATPGPGLTALHRTLRSRSRPTPRPLAGPCAERGA
                     AGPFVGRDAESDLVLGVLAGAPGAVPVAVLTGMPGIGKTALAAHVAERARGLFPDGVLR
                     AGLGAGAAAPLGRLVRALGAPEAAVPEGTEARAALYRSLLAGRRVLLLLDGALDTAGLL
                     PLLPGTPGCAALVTSASRGLVVPGARPVEVPELDDGAALELLGAVAGARRARQDPAGLR
                     ELVGLCAGLPLALHLAGRRLRLEPGLSAAELASPGGTGPLARLRADGRAVEDGFRRRAQ
                     GLSPGALRALRATATAPDRFGPAEVAALLAAGEPEAAGAVEELVDSGLLAPGVSGRYRC
                     HPLVRAFARHGLGPA"
     gene            complement(18389..19078)
                     /locus_tag="M444_RS31645"
                     /old_locus_tag="M444_31630"
     CDS             complement(18389..19078)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017242129.1"
                     /locus_tag="M444_RS31645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_31630"
                     /product="response regulator transcription factor"
                     /protein_id="WP_037798876.1"
                     /transl_table=11
                     /translation="MPVLTDRTDHVTVTIHAADPLSRAGVLSLLDRQPAVRVVPWPPEP
                     EGDVPAAEAAEARVAVMLIDQIDERSTAELRRLLRGGERRVVLVARELRESELFSVVEY
                     GVQAIVWRHQATEERLVTAVRQAAQGECVLPPDVIGRVLGQMHRLRRSQRATTPPGAAC
                     TTLFGMAPRETDVLRLISEGLDTRQISEKLCYSERTVKNILHGLMTRLRLNNRAHAVAY
                     ALREGYI"
     misc_feature    complement(20229..20244)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
ORIGIN
        1 ggccgaccgc agcctcggcc gctccctgtg ggagaccgcc gccaccggcc gcggggtgat
       61 gggcacggtg accgcctggc accgcgaggg ccatcccctg gagctggagg tctgggcctg
      121 ccccgtgtcc ggccggcgcc acggcgcctc cgccgtgctc gtcttcgccg ccgacgccca
      181 cgccgcacgc cggatccggg gttcgtcggc ggtctgggac ggactgttcg cccgctcccc
      241 ggtcggcatc gccgtcctcg acacgcagct gcggttcctc caggtcaacc cggccctgga
      301 ggagatgaac ggcctgccgg agtccgccca cctcgggcgg cgcctggccc agctgctgcc
      361 cgaggtgaac tccgccgaga tggaggaggc catgcgggag gtcctggcca ccggcgagcc
      421 cgtcctggac cgccgccggg tgggccgtac accggccgac cccgaacacg accgggtgtg
      481 gtcctgctcc tacgtccggg tcgaggaccc cggcaaccgg cccatcggcg tgatcgcctc
      541 cctgctggac atcaccgagc agcagcgcga ccacaccgag gccgaggccg gccgccgccg
      601 gctcgcgctg ctcagcgagg ccagcgtccg catcggcgcc agcctggagc tggagcgcac
      661 cgcccaggcg ctggccgacc tcgccgtccc gtacctcgcc gacgcggtca ccgtggacgt
      721 cctggacgtc ctggcccggg gcgacgagcc cggcctcggc ctctccgccg gctccgcgct
      781 gcgccgcctg ggcaaggctc cgctgggcgg ttccgccgtc accgacatcc tcgcgccgct
      841 gggcaggacc ctcacattcc ccgccacggc cccgtacacc caggtgctgg ccgaccggca
      901 gccctacctg atcggccggc tcgacgagga gtccgtcgcc cccgccgccc ggcactcgcc
      961 gaagcccgcc cggctgctga cggccggcgt gcactccttc atgatgaccc cgctggtcgc
     1021 ccgggacgtg gtgctcggca tggccacgta ttaccgcacc cgccccatcg gccccttcgg
     1081 ctccgacgac gtcaccctcg ccgccgaact cgccgcccgg gccgccatca gcatcgacaa
     1141 cgcgcgcctc taccaccacg agcacgagac cgccgtcatc ctccagcgca gcatgctgcc
     1201 ccagcacatc accccgccgc ccggcatcga ggtggcccac cgctatctgc ccgcgagcga
     1261 cgtcaacgag atcggcggcg actggtacga cgtgctcgcc ctgcccgacg gcaaggcggc
     1321 cctcctcatc ggggacgtga tgggccacgg catccccgcc gccgccgtca tggggcggct
     1381 ctcggccacc gtccgggccc tggcccgcct cgacctgtct cccacggcgc tgctgctcca
     1441 gctggaggcg gccctcgccg acctcgccga gccgatgctc gccaccttcc tgtacgtggt
     1501 ctgcgacccc gcgtccggcc gctgcaccct gacccgcgcc gggcacccgc cgcccgccgc
     1561 ggtgctgccg gacggcaccg tccggctgct gaccaccccc cccggcgcgc ccctgggggt
     1621 cggcggcatc gccttcacga ccagcgaggt caccctgccg gcgggcagca tcctcatcct
     1681 ctacaccgac ggcctgatcg aggcccgggg ccgggacatc gacgagcgcc tcggtgaact
     1741 cacccgcctg ctcaccgagc cgcagggatc gctggagctc ctgtgcgact ccctgatcag
     1801 ccacctggtc ccggcctcgg ccgacgacga catcgccctc ctcaccgccc gcatcggagc
     1861 cgtcaccccg gtgtgacggc agcggccccc acggcccggg cggggccgtg ggggccgctg
     1921 ccccgagggg tcagtggaac agcatcgagg cgtccccggc ggccgtggtg accgagccgg
     1981 ggcacaggaa gctccccgag gtcttcacgg cggtgaaggc ctggttgacg tacttccggg
     2041 tggccccgtc gcggttccag acggtgttcg ccgccttgta gcggcaggag atgaagctca
     2101 tcttgccggt gatgtcgatg aggtccgcct tcgcggtccc cgcggtgtcg tcgaaggtga
     2161 aggcggggtt gttgttgagg gtggcggtga tgccgccggc gcagctcagg ttgccgcccg
     2221 gcgtgttgat gctggtgcgg tcgacgctca gcgcgttcgg cgggtcggcg ctggtacggg
     2281 cgttggtcca gccgcaggtg ttgcccgcga ccacgatggt gccgtccagg cgctgctcgg
     2341 cggtggggcc gagggcggag gccgccgtcg atccgacgag cacgacggcg gcgaccaggg
     2401 cggtcacggc cggcagtctg gggattctca tcatggggct cctcttcgcc gcggccgtgt
     2461 ggggtgtggc cggggaaggg gaaggtccca caaggacctt gaaatgtcag ggtcacgtca
     2521 atcattggcc gaatggcacc gtccccggtg cgctcagagc caggggatct cctcggccgc
     2581 gtagcggtag gcgcggaaga cggagttctg ggcgccccgt gaggactcca ggcccacgcc
     2641 ccgtccgaac gagccgaact cggggaccac gtactcccac accacgtccc cgtccggggt
     2701 cacctcgaag agccggccga aggagccctc ggcgatgaac gtgttgccgc ccgggagccg
     2761 ctgggcgctg gacatgtacg ggctgtagaa gttctgcggc gggttgtcct cgtacgacca
     2821 cacctcctcg cccgtgcggg ggtcgatctc cagcacccgc gagtacggga cggacgtggt
     2881 gtcgcgatag gtcccgttgt cgaagaccag gatgttgccg cccggcagtt cgtgcgggta
     2941 gtgctgctgg gagtgcgcgt ccgggccgat ccgccagcgg acggagccgt cggcgcggtc
     3001 cacggccacc gtggtggagg cgctgcggaa ccccacgacg acgccgccgt cggcgagttc
     3061 gcccacggtg ttggccatag gccagtgctc gcgcgcgaag tgccggttca gtggcacctg
     3121 ttcggggttc agatgctcga tcgcggccca gcgccagacc acttcgccgt cccaggtcag
     3181 ctcgtacacc acgtccccgt ggatcacgcc gcccgcggcc tccgagccgg ggatgccgcc
     3241 gcggacgcgg gcacgcgtcg gcgggggcga ggggctcgac gccgaggacg agcaggttgc
     3301 cgttgcgcag gaccgaggcg tcgtggtggt ggaaggggtg gcggagctcg cgcaccacgg
     3361 cgccgtccgg ggcgagttcc tggaggatgc cgccgtggta gacgtcccag aaggggaacg
     3421 ttccggagcc cccgagggcg ccgatcggcc atgcggtacg ttcggctggt gtcccgaccc
     3481 gaacccacac ccgaagccgt cgaggtcgga cgggtgatcc gagcctggcg caagcggcgc
     3541 ggcatctcga tggcctcgct cgccgccggc tccgggctgt cccagccctt cctcagccag
     3601 ctcgaacgcg ggctcgccac ccccagcctc agctccatct accggatcgc cgaggccctc
     3661 gacgtgaccc ccggcacctt cctgcgcccc ccggaccgcc ccggcgcggt cagccatgag
     3721 agcgaccccc aggtgatccg ggtcagcgag gccgccgggc aggtggcgcg ggtgctgatc
     3781 cccggcgggc gcagcggcct gatggaggcg tacgagcacc acttcgagcc cggacggggc
     3841 gagcgcggct ggttcgagca ccccggcgag gacttcctgt acgtcctgga gggcgaggtc
     3901 gtgctggagg tcgagggcga ggagcccctg accctgcgcg ccgggcagag cgcccaccac
     3961 cgcggcgacg tcccgcaccg ctgccgcctg cccggcccgt cggccgccgc cgcgcgcacc
     4021 ctcctcgtca cggcgaacgg ctgacgggcc cgccgctacg tcagagcgcg gcctttccgc
     4081 tcgcgagcgg ccactcgcgg tgcagggcac ccagcggaac gcgacgctcc aggatgggcg
     4141 ttccgaacag ggacagctgg aggtgcagct gcccgctcag gtcgaagccg ccgtacacgg
     4201 cccacgcccc gctcaccgag gccttgccgt cgctcgacgc ggaggccttg acgtctgcct
     4261 cgccgcgcag gtacggggcg aagtccgcgg agacgccgac ggcgccgtac aggccgacgg
     4321 aggcctcggc gccgagggcg cccttgacct ggccggccgc ggtgacctcg gccttcaccg
     4381 gagtgctctg gacgttcgag gtgctgaccg gattccagcc cttgcccgtc gcgtagctgc
     4441 cgccgacccg gaagtcgccc ttgacttcct gccggacgtc gagggtgacc cgcccgtcgg
     4501 cctcgacctg gacgtagacg gtcagatcga ggttgacgac gaccggaacc gggcccacct
     4561 ggatgaccgg ggcgctgtgc agcttggcga acgggatccg cttcggggcg cccgtgctcg
     4621 cggcggcgtg gcccttgagg ttccactgcg aggcccagtc gccgctcatc ccgaggaacg
     4681 cggtgcgcgg accggcgccg cccgatccgt cgtacgagaa ctccaccgtc ggggcgagct
     4741 ggacgaagcc ggagaccgag gccccggccg atacgggggc acccggggcg gtctcgaccg
     4801 ggacgtccac gtcgagccgc aggttgccca ggggcagctt cgcgccctgc gggccgaacc
     4861 gcacgccctg gctcttggcc caggagaagg tgacgccctt catcaggggc tcgaccgcga
     4921 ccgaggccgg gtcgacgggg accttgccgt cggccttgtc gtcgttgagg acggaagaca
     4981 gcgttgtcgg agccgtcttg acctcggtgc cgctgtcggt cttcttgccg acctcggtga
     5041 ccttcgcgag gaggccgttg ggggcgcccg gcgccggtgc gctggcgatg acgtcgccca
     5101 cgacgacggg cttctcggcc gcgggggagc ggcccgggga gggggtggcc cgctgcgggg
     5161 ccgaggatat gacggcccgt ccggtcgcct ggtcgtagga ggcgaccttc agcgaggact
     5221 tctcgggggc gcccttcccg gagccgacgc gggccacggc cgtcggcgtg gggctgccct
     5281 gcggcgccgc ggcgacgtcg agctgctggg tgccgtcggc cgcgggcgcg agggtggcgg
     5341 gggccgcggg atccgccgcg ccggagtgcg tggcggagga gcagccggtg gcggtgagcg
     5401 ccagggtgat gaggccgggg agcaggaggc gtctggcgag catgcgcacg tacgtaagac
     5461 cttctggttg gggggaggtt acgctactga gaagtaacgt gagggttgat catgccaggc
     5521 acgatcacca cacctgtccc cgcaccagcg ataaccggcc accccccgaa gcccgttcgc
     5581 cccggccggc ggtcagcctt ccatagcccg ccgcagcccg agccggtcgg tgcccagctt
     5641 ggtgaagacc gcggacagca gctcggagac cgcctgcgcg tcggtccgta gctccgccgc
     5701 gatcgccgcg ttgtccagac cgaccgaggc gcgcgtcgcc gccgcgtgct cggcgagcgt
     5761 caacgtgtcc tgttcggacg cgtgcagccg gcgcggccgc agacccgccg acgccagctg
     5821 ggaccgggca cggctcacga gcccgctcgc cccgcacgcc gaggcggcct ccatgccccg
     5881 gtagagctgc tgggccgccc ggtgcggatc accgatggtg tgcagggccg taccgtgatc
     5941 gatcagcgca tgggcgagtt cgcaggcggc cggggactgt tcgaggtggt tcaccgcctc
     6001 ctgcaacaag cccgtcgccc gggacgcgtc cagggtcgcc gccgacacgc gcagggcgtg
     6061 cccgatcgcg ctcgacgtcc cgaacacccg ggcccgggcc accgcctcgg ccgccgtggc
     6121 acgcgcctgc tcgggctcct tcgcgatctg ggcgagggcc aggtcgagct gccagggact
     6181 ccaggacgga ttgcgcgttc cccgcagatc cagccgcttg cccgccgcgg agaggtgctg
     6241 ctttgcctcg tcgatccgcc cctgcgccag caggagcttg ccccacaccg cctgcggatc
     6301 ggggtagacg accgcctgcg ggaagccctc cgccagcttg tacgcgtggg cgacccgcag
     6361 cgcctcctcc gtactgcccc gggccagcag cgtctcgatg agcgtgccca ccgcgtacca
     6421 ctgcgcccgg gatgtcgtgt ccgacgcgct cggcgatctg gagcccgttg cgcacgaagt
     6481 cctcggcctc ggcgagccgc ccgcgccgga agcggacgta gccgagcagg gtgtacacga
     6541 acgaaaggtg cgcgccgcgc cagcccttcg actcgaactc catgatgccc gcgttgaaga
     6601 gttcctcggc gcgccccggc tggtcgcagt acatgagggt gaccgccacg acggccggca
     6661 cctcgaaacc gaagtcctgg tcggtccagt tcatcccgcc gtccagcgcc tgctccgcgt
     6721 actccagggc ggtggcggcc ggttcgccgc gcatggcggc gtcccacgcg cgcagtccca
     6781 ggatgtgccg ctcgggaacg ccgcggccgg tgagccgctt ggcgaactgc gcgaggaggc
     6841 gggagcgggc cggcgagttc gcctcgtcca tccggaccga gttccacttg aactgctcgg
     6901 cctgcatccg cagccgggtg cgggagctgg tggccagctt ggcctcgtcg gagagcagcc
     6961 cggcggcctc cgcgagctga cccgtgtggg ccatcgcctg ggcgagccgg tacgtgatcg
     7021 cctcccgcag ctcctggtcc gccttgggtt cctccagcgc ggccctgagc tggttgatgg
     7081 tggtcgcggg atcgtgcagc aggttggcgg agccgagctc gaagagcacc tcggcccggt
     7141 actccgcgtc cggcggctcg cgcagcgcgc gggccaggta gcggcgcgcc gcgtcgggag
     7201 cgcccgcgga gaagctgtcc cgcgccgcct gccgcagctg ctgcaccacc caggggtcgc
     7261 cctcggggtg catctccagc aggtggcgcg cggcggccgc ggcgccgaac ccgtcgtcga
     7321 ccagggcctg ggcggccatg ccgtgcatgg cgacgcggac gcccggcggg atcgaccggt
     7381 acacggccgt ggcgatgagc gggtggaaga actccacgac ctcctggcgg cgcaggctgg
     7441 tgaggacggt caggatgcgc gcgtcacgca actgcgcgat cgcgtcggcc gcctgtgcct
     7501 ccccgagggc cgcgacgcct ccgacgatgc tgatcgggac tgcggtgccc agtaccgcgg
     7561 cggcccaggc gagccggacg gtggaggtcc ccagctgttc gaggcggtcg atcaggccgc
     7621 tgcccttgac ggcggaggcc aggtcgcgca gctgggggat gctgtcctgg tgcggcttca
     7681 gaccgcggtc gcggcccttc atggcgagtt cgacgacctc gaaggggttg ccgccggtga
     7741 tcgcccagca ctcgcggcag aagacgtcgt cggcgttgtc gccgagggcg tcgcgcacga
     7801 tgcgcgccac ggcgctcgtg gtgagcgggg ccagttcgtg aggtcgcgtc ccctggcgct
     7861 ttatcagggc gcgcagtgat ccggcgtcgg ccgggatctc atcgggccgg cacgccacca
     7921 tgatcagcat ggccagttcc tcggcccgcg ccgcgaacgc ggtcagccag gccagggact
     7981 ccgcgtccgc ccagtgcgcg tcgtccagca ccaggaccac gggcgcgctg cggaccgtca
     8041 gatgggtgac gacccagtcc aggccgtcac gcacgccctg cgggtcgggc gcggtgaggc
     8101 cctcgggagc cgcggtcagc cccagcgccg gggcgacgat gccgtaccag gtgccgagta
     8161 cgtcgcggcg ttcgtcctcg gtcatggcgg cgaacgcggg ctggatgagc tggcgcatca
     8221 catggaaggg gacttgcctc tcctgctcgc cgccacgggc gaacagcacg gtgcagtggc
     8281 gttcggcggc atgccgtcgg gcctcggtga gcaggctggt cttgccgatg ccggccgatc
     8341 ccgcgaaggt cagaaccccg ccgcggcggg agggctggct gctgtcaggg gtgccgcaga
     8401 gctcgtccac cgcccggtgg atcgccagaa cctcggattc cctttcgagt aagggctgag
     8461 acgcccatcc ctgtggttct gtggcatacg acattctcca gccccctcca gcgcgcgtgc
     8521 cgtcgagtct acgggccagt aggaaagttg gtgctcctta agcacattat ctccgcatct
     8581 cgccactcgt tcgagggaga cgctgtatcg tcggctgact tcggcgcgga acggcgctat
     8641 cttgcgaccg gaatcatggg gagttcgctg ggctggggca ttccggccgg gagttcacgc
     8701 accgtcacac ccggggcggg aaccaatcgc cagcgggacg ccacggtcgc caccgccgtc
     8761 aggatctccg ccaccgcgaa cgtgtcgccg atgcacttgt gctggccggc cccgaacggg
     8821 atgtactggt gcgcgcgccg gcggtcctgc gcctcctgct gccagcggtc cgggtcgaag
     8881 accccggggt cgcggaacag ggccggatcc cggtgcaacg cataagggct gtaggccagt
     8941 tcggcgcccg ccgggatcga cacgccgccg agcgtgaggg gcaccagggc ctgccgggtg
     9001 aagagcagcg gcgagtgcat ccgcagcgct tcctggaaca cgttgttcgt gtaggtgagc
     9061 tgggggatgt cgccgatgcg gacgggccgc ttgcccacca ccgcgtcgat ctccgcgtgc
     9121 aggcgcttct ccgcctcggg gtgccggccg agctcgtgga atatccacgc cagggtggtc
     9181 gccgaggtct ccgtgccggc gaacatgatg gcgatcacct cgtcccgcac ctgtgcggcg
     9241 tccatccgct cgcccgtctc ggcgtccacg ctcgacagca gcagggagag gaggtcgctg
     9301 ccgccctcct gcgtgtcccc gtactgggcg atcacctggt cgatgatcgc gcgcagccgg
     9361 gcggccgccg cgtcgaagcg ccggttgagc gggacgggca gccggtccag cgacttgggc
     9421 atgaccgcgc gcagcagcat gccctccagt acgatcggca gcgagcggtg cacctcggcg
     9481 atggccggac ggctcagatc ccccgagaag atcatctcgg cgaccgagga cagggcgtac
     9541 cgccgggcct cggtgaccat cgagatctcc gaacccgccg tccaggaccc ggtcatctcc
     9601 tccgccgcgc ggcccatcac ctcggcgtac tcggcgatgt ggctgcggtg gaacgccggc
     9661 tggatcatcc ggcgctgctt gcggtggaag tcaccgtcgg tcgtcacgat gccgttgccg
     9721 aacatcgggc ggagccggtc gaatatcctg ccgcgcccga acttctgtgc ctgctgcacc
     9781 agtacggcgt ggacgtggtc cgggttcgtg agcatgtgga cgggccaggt gccgatgtcg
     9841 agccggacga cgtcgccgta ctggcgcagg gactccagga acgcgatggg ctcgcgccac
     9901 agggggaggg catggcccag gagcggtaat cgccccgggg ccaccggggc gctcttcgcc
     9961 aggccggatc gttctgtgcg ggccatggac cgactccctg tcatgccacc gagatcaggt
    10021 ccgggcgggt gtacgcagac tccagcccgg ccgcgaaccg ttcgtcgctg taccgcgtgc
    10081 actcgtaacg ctgccacaga tcggcgccga tgatccagtc ttgataactg cgcacgcagc
    10141 gggtgaccgc ggtgcgtacg gagggatccg tgtccgggcg cgcctccatg agccgcagca
    10201 gccgccgctc ggactccagg tactcctcga tgcgggcctg gatgcggccc tcgaccgcct
    10261 ggacggcatc gggcagagag cgtccctccc aggtggcgac gagggagacg aggttgttgt
    10321 tgtccccgca ggagtactcc ttcggcaggg agaacacgtc gttgccccag gagatgacgt
    10381 ccagggcgct gtcgacgacc gcccggaact ccgggaggtc gtggatgtgc tgcggcaggt
    10441 cgatgcccag tccggcctcc accatgtcca tcatgggaag gatctgggag ctgtgccggc
    10501 gcatcaggat gtagtcctgg agcgcgggcc gctcggccgc ccggcgattt ccggcctcct
    10561 ggtccaacga gcccagcatg agcgggacat gggtgcggta gcgggccgcg gtgccctgcg
    10621 acatcccggc cagtatccgg tcgcacaggt ccatgaaccc ggccaccagg gggttctggc
    10681 gcgccgaggc gtcacccgcc ttgcccgtct ccaggtattc ggtgatcgct ccgatgacgg
    10741 ggcgccaggc ggccacctgg cccgtcctga tgaggtggtc gtgctggtcg tcgaggacga
    10801 acgaccaggc catccactcg gcgagcagga ggatccggtc gtacgggacg tcgccgctca
    10861 cccggcccgc gaggtggccg cagccgatgc cggagaattc ctcggcggcg tgcgtgacga
    10921 gctcgtggcg caacacccat gacgtggcct cggtgttggc ccgtgcggcc tgcggatgct
    10981 tggagttccc gaacggaagg tgaaagtcgg gaacggtgaa tgagtggagc tgggccattg
    11041 atcccccacg gcagagtcgg attcgtcaat accagctcaa tgtaaagagc gtgactgccc
    11101 gcgcgcgcca gaacgcctcc tctgctgcgg agttgtcatg gcgacacacc ggagcacatg
    11161 gaatgaaccg gtcgcggagc gaccaaatcc cgcccacgcg cgaccgtatc aggccacccc
    11221 tggagtggtt aaggcttgtg acgaggtgca ctgccaaact ggaagtgtcc ttccgcgaat
    11281 tcaccctgga attgccgctc cgatattcca atggcgcatg cggctggcat agtcggaccg
    11341 cccggccgcc cgggaggcgc tgccgggggc ggcctccccg ggtgtggccg aacagcaccc
    11401 cgtcgacggt ggcgctctct acacttccag gggacgcggc cgtccggaga agggcgagaa
    11461 catgaccgac caccatccgg caggcccggg ggacggccag gacgtcgacg tcctgggccc
    11521 ctacctggaa gtcttacggg cgcgcctgac cggtgagcgg ttcgaggtgc tcatccgggc
    11581 ggtccagacc acctgcgcac tgctggccga ggaccaggag accgtcctca aggtgccggc
    11641 ggccaccgaa ctcgcccccg atctccagcg cgagtacctg tccctcatgg ccgtgatgat
    11701 caccggccac ctcgaccacc ggctggtcga gatcgccgcc cccgacgggg gcaggggctg
    11761 ggcggtcgtc gacaacaccc gcccctaccc cgcccgtccg gcggacgtca ggagctcgtg
    11821 agcaccacga gctgccgggt cgcccgggtc atcgccacgt agcggtcgac cgcgcccggg
    11881 gagccctccc cgaactcctc cgggtcgacg aggacgacca ggtcgaattc gagccccttc
    11941 gagagctccg gggtcagtga ccggacgcgc ggccgcgccc ggaacgcacc cgctgccccg
    12001 ccgggcgagc cgatgacgca ggcggtcccg gcctcgtgcc cggcgagcca ggtgtcgagg
    12061 acgtcgtcca ggtcgcagac gcagccgtgg acgacgggga cgccgccgga ccggatcgag
    12121 accggcacgt tggcgtcggg cagcgcggcc cggatgaccg gctcggcctc cgccatcacc
    12181 tcgcgcggcg tgcggtagtt gatgctcagg gaggccagct cgatccggtc gatcccgacc
    12241 cgctccaggc gctcggtcca cgactccgtg aagccctgcc tcgcctgggc gcggtccccg
    12301 acgatggtga agctccggga ggggcagcgc agcagcagca tctgccactc cgcgtcggtc
    12361 agttcctggg cctcgtccac gacgacgtgc gcgaagggcc cggcgagccg gtccggggcg
    12421 gccgtgggca gggcgccctc gtcgatcagg ctgtcctgga ggtcccttcc gcgcagcatc
    12481 cgcaccgcgc cctcgctgtc gtctccggcc gagtcgatgt cggcgaccga gacgatctcc
    12541 tcgatgaccc gggacatgcg ctcgcgctcg gcggcgaccg cggcgtcgtg ccggcgccgc
    12601 cgccgcgccg ccccggggtc cccgagccgc tgccgggccg cgtccagcag cggcaggtcg
    12661 gacaccgtcc aggcctgggg ggccgcctcg cgccgcagct tcgccacctc gtcgcggccg
    12721 agccagggag cgcacatccg cagataggcg ggtaccgtcc acaagtccga gaccaggtcg
    12781 gccggttcga gcagcggcca ggcccgggtg aaggccgtga ccagctctgc gtcctgccgc
    12841 agcgaccgca ggaaggcggc gtgcgagatg ccgtcctcct cctcgtccat gccctgcttg
    12901 tccatgagga tcgtggccag ttcctcccag atctgctccc gcgcctcgtt gtgcgggctg
    12961 cccgggcccg gcgccccgaa cgcctcggcc cagtcgtcgg ggctcacccg gacgtcgccc
    13021 caggccgtac tgaccgtcat gccctcggcg ggcggttcct cgtagaacgc gaccgccttc
    13081 tcgatggccc gcaccatgtc cgcggacgac ttcagccggg ccacctccgg gtcgctctcg
    13141 ggggcggccg aggcaccttc ggcgacgagg tcgcgcaggg tgcaggtctg tacgccctcc
    13201 tctccgaggc tgggcagcac gtcggcgacg taccccaggt agggctcgtg cgggccgacg
    13261 aacagcacgc cgccacggcg gtggccgagg cgcgggtcgc tgtagaggag gtaggcggag
    13321 cggtgcaggg cgacgacggt cttgcccgtg ccgggaccgc cgtcgacgac cagggcgcca
    13381 cgggagtccg cgcggatgat ggcgtcctgg tcggcctgga gggtgccgag gacgtcgcgc
    13441 atccgcgccg accggctgcc gcccagggcg gcgatgaagg cggactggtc gtcgagcgcg
    13501 gcgtgcccct cgaacccgtc ggtggtgaac acctcgtccc agtagtcgtt gaccctgccg
    13561 ccggcccagc ggtagcggcg gcggccggcc agccccatcg ggttcgcgtg ggtcgccgcg
    13621 aagaacggct cggcggcggg ggagcgccag tcgatcagca accggcggcc ctcgccgtcg
    13681 gtgaggccga gccggccgac gtacagcggc tcggggtcgt cggcgccgac gacccggccg
    13741 aggcacaggt cgaggccgaa gcggcgcagg gtgcgcaggc gggcggtcag ccggtggatc
    13801 tccgcgtccc gttccatggc ctcccggccc aggccgccgg gcgccccgcg cagctcggcg
    13861 aggcggtcgg acagctcggc gatcgcctcg tcgaggctct gcgcgatggc agcgaagtgc
    13921 cgttcgtcgc cgccgatgag cgaggggtcc gccttggcgg agaggcgctc gggaaggccg
    13981 aacgcactgg tcgtcacggg gttcatgtca gcggctccga tccgcggcgg ccggccgccg
    14041 cagatcgggc cccaccggcc cggtgtcacc gtgaaaccca tatacagaca gcagcacacg
    14101 cacttcgtga atctcccatt tccgcagctt ctggcctcgg cgagcgattc tgcggcacgg
    14161 tgggggcctt gccgcaagcc ccccagcgcg ctataagttg agagtggaaa ggagtgggta
    14221 cacctccttc tccccctccc tccccttccc gctccttagc tccccgcgcg ggtgcgcccc
    14281 tcgaccggtc cggaagccgc cggagccccg ctccccgggt ggggacgggg ctccggcggc
    14341 cgtacggcgg acgcgtgggt cgttcggtgt cagtcgttga cgcagacgtt gccggccgtc
    14401 gggttcagca gcccgatgat gttgacgctg ttgccgcagg cgttgacggg gatgtggatc
    14461 gggacctgga tcaggtttcc ggagaggacg cccggggagc cggccgcgat gccgtgggcc
    14521 tcgctgtccg ccaccgcgga gccggcgccg ccgagtacgg caccggcgat caggcaagcc
    14581 gctgcggcca gggtgcggat tttcatgtgg gtctcccgtt gagtgatggg gtgtgcggag
    14641 ccatcccaca acaggtgcgg gggcgggccc ggacattccg ccactcgtgg gccgggccgc
    14701 ctcgtggccg ggccgccgcc caaagaagcg gagggatccg ttctaaggca gttctcatcc
    14761 cgtacccagc ttccccacag caacggggag caggatcgac cggagtcagt cgtgatcacg
    14821 gaagggctct catgaacaac gtccgcaagc gcgcgggtat caccgcaggt gtggttctgg
    14881 ccggtatcgg cctggccttc cccgccgtgg ccttcgccga ggatcactcc aagcccgcca
    14941 ccgccgccga ggcgcgcccg cacgcgggca agggcgccga gctgcgcgag gagcaccgca
    15001 aggaactcgc cgaggccctc gcgaaggacc tcggtgtgcc ggtggacaag gtgaccggct
    15061 ccctggagaa gttccgcgcc gcgcagggtg agaagcaccg cgaggagcgc aaggaccgca
    15121 aggacgagcg ggcgggcgag cggccggatg cggccgcgct ccagaagaag ctggccgacc
    15181 gcctcgacca ggcggtcaag gacggcaagc tcacccgggc gcaggcggac gccgtcatcg
    15241 ccgccgccaa ggccggggtg ctgcccgggc cgggtggcgg cccccaccac caggagcgct
    15301 gacccggctc cacagctttc gtgggcgccg gcgcgcatga atggcgccag ggatggtaga
    15361 cgcagggagg cctcttcgct cccagcgggc gaagccgtga gccgggaagt ctgggaggtt
    15421 tgtcgtgatt atcctcggag tcatcctgct gatcatcgga ttcgtcaccg gcctgtccat
    15481 cctgtggacc attggtgcga tcctcgtggt ggtaggcctg gtcctgtggc ttctcggtgc
    15541 cctcgggcac gcggtgggag gccgtaacca ctactggtga gcctctccgc tcccggccgt
    15601 aggcccaccg gaccccggat ccggtgggcc tacggcgttc tcccgggcat ccttgacggg
    15661 ccttttgggc atccttgagc tggaatagac cattccgttg gtttccggat tacgttcgcc
    15721 gcatacgggt cgtagagcgc gacccggctg aaacctggag gtctcagaca tgcgacgtac
    15781 cctcaccaag gccggcagcc tcgcggcggt ctccctcttc gccctggccc tggccgcgcc
    15841 cgcgcaggcg gcacaggaca gcgccgcggc cgcgcgtccc gccgccacga aggcggtcta
    15901 cttcgagttc accgacggca ggaacacctt cgtcatccag ctcaccgacg cggcgaagat
    15961 ccggcaggcc cgcgacgtca tcaacggcgt cgacacggag aacatcagcg tcatgggcaa
    16021 gatcgtcaag acccccgcct cgtacaacaa gccctggaag tacacgctcg cccccagctc
    16081 cgtgaagttc ttcagcatgg ccaccgaggt gtgcgacgcg agcatctcct acgtcaacga
    16141 gcacctggac gaggtgggcg gcgcgctcct gcccaattcc acctggtgtc cctggcagtc
    16201 gaagctgacg cgcgagatcc ccgctccgta ggcggcggcg aaccggacgg ccggccgccg
    16261 gacccccgcc cgcggccggc cgtccccgcg gcggcgaagt aaccttttcc ctcagtgcgg
    16321 tccggggagc ggggaggtac gtggcggaga cggagcgcgg gtgcccgctc gccgagggcg
    16381 tacggttccg gctgctcggg ccgatgaccg cgcggacggc cgacggcgcc gcgctggcct
    16441 tgggcccgaa ccagcagcgc gcgctgctcg ccgtactgct gctgcgggcg gggcggcccg
    16501 tccccgtacc cgagctctgc gacgcgctgt ggggagagcg cccgccggcg cgcgccgtgg
    16561 ggaccgtacg gacgtacgcg tcccggctgc gtgccctctt cgaaccggac cgcccggccc
    16621 gggcacccgc ccggatcctc gtcttcgcct ccggcggcta cgccctgcga ctgtcccgcc
    16681 cggcggtgga catcgacgag ttcgagcgcg ggctcaccga cgccgcccgg ctgcgaaccg
    16741 ccggagccgt ccggcaggcg taccgcaccc gggagcgcgc cctcgcgctc tgggcgggct
    16801 gcccgctggc cggcctcccc ggcccccacg ccgaggcccg gcgcgaccgg ctcaccggac
    16861 tgtggctgac cgcccgcgag gcccacttcc acgacgcgct ggaactcggc ctggaccgcg
    16921 agaccccggc cgtcccggcc ctgcgcgcct tcgccgccga acacccgctg cgcgagggcg
    16981 cccaggaact gctcatgcgg gccctgcacc gggcgggccg caccggcgag gcactcgccg
    17041 tgtacgaggc cacccgcgag acgctcgccc tcgaactcgg cgccaccccc ggccccggcc
    17101 tgaccgccct gcaccgcacc ctccgctccc gctcccgccc gaccccccgc cccctggcag
    17161 gcccgtgcgc cgagcggggt gcggccgggc ccttcgtcgg gcgggacgcg gagagcgacc
    17221 tcgtgctcgg ggtgctcgcc ggggcgccgg gggcggtgcc cgtcgccgtg ctcaccggta
    17281 tgcccggcat cgggaagacg gccctcgccg cccatgtggc cgagcgggcc cgcgggctgt
    17341 ttcccgacgg ggtgctgcgg gccggtctcg gcgcgggcgc cgccgccccg ctcggccggc
    17401 tcgtacgcgc cctcggggca cccgaagcgg cggtgccgga agggaccgag gcccgggcgg
    17461 cgctctaccg ctcgctgctc gccgggcggc gcgtgctgct cctcctggac ggcgccctcg
    17521 acacggccgg actgctgccc ctgctgcccg ggacgccggg gtgcgcggcg ctggtgacct
    17581 cggcctcgcg cgggctcgtc gtaccggggg cgcggccggt cgaggtaccg gaactggacg
    17641 acggcgccgc gctggagctg ctcggcgccg tcgcgggcgc ccggcgggcc cgccaggacc
    17701 ccgccgggct gcgcgaactc gtcggcctgt gtgccgggtt gccgctcgcg ctgcacctgg
    17761 ccgggcggcg gctacggctg gagcccggcc tgtcggcggc ggagctggcg tccccgggcg
    17821 gtaccgggcc gctcgcgcgg ctacgggcgg acggccgggc ggtcgaggac ggcttccgcc
    17881 gccgcgccca ggggctgtcg ccgggcgcgc tccgggccct gcgggcgacc gcgacggcgc
    17941 cggaccggtt cggcccggcc gaggtggccg cgctgctcgc cgccggggag cccgaggcgg
    18001 ccggcgcggt cgaggaactc gtcgactccg ggctgctggc gccaggggtg tcgggccgct
    18061 accgctgcca ccccctggtc cgggccttcg cccgccacgg gctcggcccc gcttagggcg
    18121 actcgcgcgg atcccgcccc gcccgcgccg ccgagccccg cccgcgccgc cgagcccgcg
    18181 ggagacggcc ccggcccgtc gtcaccgtgg cacccggcac cgctgcgcac cgcgccgcgt
    18241 tgcccaggcg cccgcgcctg tccggtacgg cgcctcgccg cgttgtcgga ccgggcgggt
    18301 acgtccggta cgggcctcgg ccctccgtct cgcgacgcac cgcaccgcgc ccgacgccgc
    18361 gccccggcag acccttccgg tcacggcact agatgtagcc ctcgcgcagt gcgtaagcca
    18421 ccgcgtgcgc acggttgttg agccgcagcc gtgtcatcag cccgtgcagg atgttcttga
    18481 cggtccgctc ggagtaacag agcttctccg agatctggcg ggtgtccagc ccctcggaga
    18541 tgaggcgcag tacgtccgtc tcgcgcggcg ccatgccgaa cagcgtcgtg caggccgcgc
    18601 ccgggggcgt cgtcgcccgc tgcgagcggc gcagccggtg catctgcccc agcacccggc
    18661 cgatcacgtc cggcggcagc acgcattccc cctgcgcggc ctgccgtacg gccgtgacca
    18721 gccgctcctc ggtcgcctgg tgccgccaga cgatggcctg cacgccgtac tccacgaccg
    18781 agaacagctc cgattcgcgc agttcgcggg cgacgaggac cacgcgccgc tcgccgccgc
    18841 gcaggagcct gcgcagttcg gccgtcgagc gttcgtcgat ctggtcgatc agcatgacgg
    18901 ccactctcgc ctcggcggcc tcggccgcgg gtacgtcccc ctccggctcc ggcggccacg
    18961 gcacgacccg caccgcgggc tggcggtcca ggaggctgag gaccccggcc cggctgagcg
    19021 gatcggcagc atggatcgtc acggtcacgt ggtcggtgcg gtcggtcaga accggcatcg
    19081 tcttttcctt ccccgaagtc ttgccggatg aagagtggca aagccggatc aacagccgat
    19141 cgacgcccga tgagcgttcc gcgtgatccg tccccttccg catgccttgg tacagttcca
    19201 gctgggtggc aggtacacgc acattgcgcg cgtccgtacg ggagttggaa gaggaaccat
    19261 gagcggaacg cgccccggaa cgtacttctc cctgctcgga ccggtccagg cgcaccgcga
    19321 tgattccccg ctcccgctgg gcccgcccca gcagcgcgcc ctgctcgcca tgctgctgtg
    19381 ccggcgcaac gcggtcgtgg gcctggacga gctgatcgac ggcctgtggg gcggggagcc
    19441 gccgcgctcg gcggtcggca cggtcaggtc gtacgcgtac cggctgcgcc gcgtcctcgg
    19501 cggcgggatt ttcacccacg ggcggggcta cgccctccag gtgggcccgg gggagctgga
    19561 cctgacccgc ttcgacgagc tgaccacccg ggcgcgcgcc cacgtctccg ccggtgaccc
    19621 ggaagcggcg cgggacctgc tggcgcgggc cctggagatg tggcgggggc ccgccctcgc
    19681 cgggctgccc ggcccgcagg cccgcatcca gcgcgagcgg ctcgccgaac tgcggctgtc
    19741 ggtcctgatg gagcgggtcg agctggacct gcggctgggc ggccacggcg ggctcgtcgc
    19801 cgagctgacc ggcctgtgcc tggagcaccc cctcaacgac cggctgcgca cgctccggga
    19861 cgccgccctg gaacgcggcg gccgggaacg ggaggcgcgg acgacaccgc ccggcgccga
    19921 ggcccccgcc gcccccaccc cgaccgcccc gccgcactta cccgttccgg cccaactccc
    19981 ctatgttccc ggcgacttca ccgggcgcgc cgaggcggta cgggacctgc tcgacgccct
    20041 ggccccgacg gcccccgagg cggtggtcgt ctgcgccgtc ggcgggatcg gaggcatcgg
    20101 caagaccacc ctcgccgtgc acgcggccgg acggctcagg aagcacttcc ccgacggcca
    20161 gctgtacgcg aacctgggcg gcgtacgcga ggacccggcg gaccccgcgg ccgtcctcgc
    20221 cggattcctg cgcgccctcg gcgtgacgga ccccgcgctc cccgaagagc cgcgggaacg
    20281 cgccgcgctc taccggaccc gcctcgcggg caagcggatc ctgctcgtcc tcgacgacgc
    20341 ccgggacgcc gcccagatcg agccgctcct gcccggatcg cccacctgcg ccgtgctcgt
    20401 caccagccgc agcaccctgc ccggactccc ggccgcccgg cgcctgcgcc tcgacgtctt
    20461 gcccgccgcc gaggcgctgg ccctgctcgg ccggatcgtg ggggaggagc gcatcgccgc
    20521 cgagcccgcc gaggccgcgg ccctcgtcga gcgctgcggc ggtctgcccc tggcggtgcg
    20581 catcgcggga tcccggctcg ggacgcggcc ggcctggaag ctcgcggact tcctccgcct
    20641 cctcgacggc cgccgccccg cgttcggccc cgggttcggc cccgccctcc ccggccggga
    20701 cgggcccgaa ggcagcgtcg aagcctgctt ccgcctcagt tacgacctgc tcgacgcggg
    20761 gcaggcccgg ctgttccggc tcatggccgt cccccgcacc ccgacgctgg acctcgcctc
    20821 ggcggcggcg ctcgccgggc tggaccccgc cgaagcggag cggcacctgg aacggctgac
    20881 ggcgctcggc ctgctggaat ccccggcccc gctgacctac cggttccacg acctgctggg
    20941 ggagttcgcc gccgcccggt ccgaggaacg cgacagcccc ggggaccgta cggcggccct
    21001 cctgcggctg gccgaccaca tgctggcctg tgcccggg
//
