LOCUS       NZ_CP011664            22637 bp    DNA     linear   CON 03-MAR-2024
DEFINITION  Streptomyces sp. Mg1 chromosome 1, complete sequence.
ACCESSION   NZ_CP011664
VERSION     NZ_CP011664.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. Mg1
  ORGANISM  Streptomyces sp. Mg1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     De Novo Assembly of the Streptomyces sp. Strain Mg1 Genome Using
            PacBio Single-Molecule Sequencing
  JOURNAL   Genome Announc 1 (4), e00535-13 (2013)
   PUBMED   23908282
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUN-2015) Biochemistry and Biophysics, Texas A&M
            University, 300 Olsen Blvd., College Station, TX 77845, USA
REFERENCE   3  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JUN-2013) Biochemistry and Biophysics, Texas A&M
            University, 2128 TAMU, College Station, TX 77843, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 8.2
            Genome Coverage                   :: 30X PacBio; 80X Illumina
            Sequencing Technology             :: PacBio + Illumina MiSeq/HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 08:10:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,822
            CDSs (total)                      :: 7,726
            Genes (coding)                    :: 7,467
            CDSs (with protein)               :: 7,467
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 260
            CDSs (without protein)            :: 259
            Pseudo Genes (ambiguous residues) :: 0 of 260
            Pseudo Genes (frameshifted)       :: 109 of 260
            Pseudo Genes (incomplete)         :: 200 of 260
            Pseudo Genes (internal stop)      :: 18 of 260
            Pseudo Genes (multiple problems)  :: 60 of 260
            CRISPR Arrays                     :: 11
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:43:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6990660
            Orig. end                         :: 7013297
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011664.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Paul Straight
            (paul_straight@tamu.edu).
            Annotation modified by the submitter.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22637
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="23"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22637
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22637
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12637](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12637)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(229..244)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.55"
                     /tool="antismash"
     misc_feature    478..491
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.35"
                     /tool="antismash"
     gene            481..1839
                     /locus_tag="M444_RS30195"
                     /old_locus_tag="M444_30180"
     CDS             481..1839
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743197.1"
                     /locus_tag="M444_RS30195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30180"
                     /product="hypothetical protein"
                     /protein_id="WP_008743197.1"
                     /transl_table=11
                     /translation="MDTHEDLGTGSGHPWFGRHRLRPAAPADTIRRMLRHELRDTGWPY
                     QRVLPAAPMAIPRASYAEIFRVSVALIELLRRTALESGPTTADRLSAYDMPATEDRLWM
                     GDPFVEERYADSVVRPDLVIGPDGPRFLEFNVSGALGGVVETRSRLAVWRGLHADEDGR
                     TPFRSPDPFDVRADMFRSLGAELGLAPRVAVVGSARVIGVERRYFEMEADHYNSHGLTA
                     RFFEPEELPEAWDCAPHLRHQVGLRNFTIPDWLEVGIDTTPVQDALDNGCLLVGTQTST
                     FMHSKLTMGLLSEGRPWMTAADRGLVERYLPWTRILSERKTDREGQQVDLLPFVLGNRE
                     LLVLKAGLGESGKQVVIGREVDQAGWESAVGAAVAGGTSVVQAFVEPQTCRVSLIADGC
                     DEPYDADVAPVLGPLVFGGRPAGLFCRFFGDGSAGIVSVRGGTSSSDNVMVAI"
     gene            1899..2180
                     /locus_tag="M444_RS30200"
                     /old_locus_tag="M444_30185"
     CDS             1899..2180
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156263.1"
                     /locus_tag="M444_RS30200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30185"
                     /product="DUF3253 domain-containing protein"
                     /protein_id="WP_008743196.1"
                     /transl_table=11
                     /translation="MTHGDRETERRLERAILELLEGRGPTATICPSDAARAVYAGSDDG
                     WRVLMEPARRAARRLVGAGEVEITQAGRPVDPATARGPVRIRTARRRP"
     gene            complement(2198..2860)
                     /locus_tag="M444_RS30205"
                     /old_locus_tag="M444_30190"
     CDS             complement(2198..2860)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031786.1"
                     /locus_tag="M444_RS30205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30190"
                     /product="deoxynucleoside kinase"
                     /protein_id="WP_037794821.1"
                     /transl_table=11
                     /translation="MPVICVGGMIGIGKTSVAELIAKELGSEVFFESVEDNPILPLFYT
                     ASPEEIQAKRYPFLLQLYFLQTRFASIKDAYHRADNVLDRSIYEDWYFAKVNHDLGRIS
                     SLEMQVYEGLLGEMMREIEGLPYRKAPDLMVYLKADFETVMYRIGLRGRDFEQDEALVE
                     YYRTLWSGYDDWVHKHYSASDVLVIDMNRTDVVNNPEDAARVAQEVKDALAAVAARR"
     gene            complement(3120..3671)
                     /locus_tag="M444_RS30210"
                     /old_locus_tag="M444_30195"
     CDS             complement(3120..3671)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999362.1"
                     /locus_tag="M444_RS30210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30195"
                     /product="YciI family protein"
                     /protein_id="WP_008743194.1"
                     /transl_table=11
                     /translation="MEFFCYHRDRPGSTALRMELLERHWSYMDQYEKELIARGPTFAPG
                     GDAPSGSVHIVDLPDPAAARAFAFDEPGYQAGVYRDVLLLRWRDMLGRTMWDFPGGRTG
                     GNRYLVLGLGAGGAADLTAAPGCRNDLIAYGPLLSDDATTWLGTAALVRAPDADAARGV
                     LDVERYADIEIHPWEFGGRR"
     misc_feature    complement(3655..3671)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.34"
                     /tool="antismash"
     gene            3783..3971
                     /locus_tag="M444_RS30215"
                     /old_locus_tag="M444_30200"
     CDS             3783..3971
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014050098.1"
                     /locus_tag="M444_RS30215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30200"
                     /product="DUF6381 family protein"
                     /protein_id="WP_037794818.1"
                     /transl_table=11
                     /translation="MSVEDPSGKRAQEMRDKAQELEQAAQYAADPAERQRLTQKALHIR
                     EKSEQVYGFGAGTMDPM"
     gene            complement(3991..4935)
                     /locus_tag="M444_RS30220"
                     /old_locus_tag="M444_30205"
     CDS             complement(3991..4935)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140526.1"
                     /locus_tag="M444_RS30220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30205"
                     /product="5'-nucleotidase"
                     /protein_id="WP_008743192.1"
                     /transl_table=11
                     /translation="MRYDLSSRLVVGIASSALFDLTDCDAVFREQGEDAYRAYQEAHAD
                     HALAKGVAFPFVRRLLSLNDLSDRSDPLVEVIILSRNDPDTGLRVMRSITAHHLPISRA
                     VFRQGRPSHSFMRALNMSLFLSANGADVRDAVAAGLPAGHVLHTARIDDESDPELRMAF
                     DFDGVLAGDASERVFQSLGLDEFRAHEVREAATPHDPGPLRPFLAGVNRIQRREEERRR
                     GDPAYQPRLRVSLVTARDAPTHERAIRSLKDWGLRVNDAFFLGGIEKTAVMRTLDPHIF
                     FDDQVSHLNGTAHGTPSVHVPFGVVNAQPPATT"
     gene            5298..5903
                     /locus_tag="M444_RS30225"
                     /old_locus_tag="M444_30210"
     CDS             5298..5903
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142169.1"
                     /locus_tag="M444_RS30225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30210"
                     /product="response regulator transcription factor"
                     /protein_id="WP_063781037.1"
                     /transl_table=11
                     /translation="MTKVLVLHSVCLVRSALAALLRTEGDFDVTSCGWRAAGRQAASLR
                     PDVAVVDLDCPGASAALLADADAARPFPRSTPLLVLARADTPGSLRRAFLTQAQGYVDK
                     DGSPARLVRAIGRVAAGERSIDATLASAFMEADPMPLSPRELSVLARAAEGDSIAEIAR
                     ALHLASGTVRNYMAAVTRKTGARNRIDAIRISRRAGWV"
     misc_feature    5427..5429
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5935..7677)
                     /locus_tag="M444_RS30230"
                     /old_locus_tag="M444_30215"
     CDS             complement(5935..7677)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972311.1"
                     /locus_tag="M444_RS30230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30215"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_037798699.1"
                     /transl_table=11
                     /translation="MSGDGSWRRVSREGRRFLRGRYRSLRRLALWSLLESAHTFLGGYA
                     VARALDDGFLAGRTGTGLGWLAVAGAGALLGALALRGVFGGLADLVEPLRDGLVRRSVR
                     QAIGRAVADPGRAGDAGAVSRLTQQTEMARDSFAGLVLVARSFVFTALGALLGLAALDP
                     VLLVLVLPALLLGTAGFLATLRPMARVQRAALDADEALSGRAGELAAGLRDVVACGGGA
                     SAGAPVERLIAEQERLTGRLARWSALRTLALGVAGRLPVVALLAGTPWLLGRGVSAGAV
                     AGALTYLVQSLLPALDALMTAVGAAGTRLLVVLDRFCAPQSDSAAATTAPAVAPGVGAG
                     PGVAVELRGVWFAYGPRAQPVIDGLDLTVGAGEHLAVVGPSGIGKSTLTALIAGLLPPG
                     GGTVRVAGAPAQGVTGPGPDLRRTLLPQQAYVFTGTVRENLTHLCPGPVSGAEVERATA
                     ALGSDGLVDRLGGLDGAVDPARLSPGERQHLALTAAYLSPAPLLLLDEATCHLDLRTEE
                     RAERALAARPGTLVVVAHRISSAARADRVLVLDGTRAVCGTHAELPARSPLYRDLVGLW
                     NARG"
     gene            complement(7674..9800)
                     /locus_tag="M444_RS30235"
                     /old_locus_tag="M444_30220"
     CDS             complement(7674..9800)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020551012.1"
                     /locus_tag="M444_RS30235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30220"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_063781038.1"
                     /transl_table=11
                     /translation="MTAPDPTREAEAARGADRALRAAARHSGGRLAAAAVCSVAAAGAA
                     LAEPAVLGHTLDLLLRQDPGGARWTAWCAAVIAAEVLLDAVTARLTGGVDARSTAWLRR
                     LGLGRLLRAAPHHAARHSPGELSARLTAQATTAGAVPAAVVGAAVALLAPLGGLVALVL
                     VDVWTALAFLAGLPLLALLLRAFARDSGASVGRYQEVQLAMAGRLVEALAGARTIAAAG
                     TAEREQARVLRRLPELGAEGRETWRIYGTTMARTGALMPLLLYVVLGVGGIRLAEGALG
                     VGGLLAAVRYAGLAAGVGAVTGRLAAVVRGRAAARRTAALFELPELPQGVSRLPPGGPG
                     ALELRGVRVVRGGTAVLRDIDLRIPGGTTAAVVGRSGSGKTTLAAVAGRLTACDAGRVL
                     LDGVPLDELSAGELRREVGHAFERPALFGEDVAAAIAFGSGPAPPPENVRAAARAAGAD
                     AFVRRLPDGYDTALPDAPLSGGELQRLGLARAFCRAGRLLVLDDATSSLDTLTAREVER
                     ALTHDVRPGTRLVVAHRISAAARADLVVWLDAGRVRATGPHTELWRDPAYRAVFATGTE
                     PADPPNTQPAAAPVPPAAGGPDAQRNTDSDAATGAARAWAEGTASEPDTESAAAPVPPA
                     AGRPDAQRNTGSDAAAGAAPARAEGTGSEPVAAASPRTGAAPGEGPDAGASAGTGSAAA
                     GGGGRRAPGRETVR"
     gene            complement(9867..10004)
                     /locus_tag="M444_RS30240"
                     /old_locus_tag="M444_30225"
     CDS             complement(9867..10004)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946992.1"
                     /locus_tag="M444_RS30240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30225"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_030723876.1"
                     /transl_table=11
                     /translation="MTLLDLQSMETPKEETTEAAHGGGGGSRASLLLCGDSSLSITTCN
                     "
     CDS_motif       complement(9942..10004)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTLLDLQSMETPKEETTEAAH"
                     /locus_tag="M444_RS30240_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9867..9941)
                     /prepeptide="core"
                     /locus_tag="M444_RS30240_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="20.90"
                     /molecular_weight="2100.3"
                     /monoisotopic_mass="2099.0"
                     /core_sequence="GGGGGSRASLLLCGDSSLSITTCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTLLDLQSMETPKEETTEAAH"
                     /leader_location="[9941:10004](-)"
                     /alternative_weights="2118.3"
                     /alternative_weights="2136.3"
                     /alternative_weights="2154.4"
                     /alternative_weights="2172.4"
                     /alternative_weights="2190.4"
     gene            complement(10001..12637)
                     /gene="lanKC"
                     /locus_tag="M444_RS30245"
                     /old_locus_tag="M444_30230"
     CDS             complement(10001..12637)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849361.1"
                     /locus_tag="M444_RS30245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30230"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_037800090.1"
                     /sec_met_domain="micKC (E-value: 9.7e-240, bitscore: 796.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2e-11, bitscore: 42.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.1e-06, bitscore:
                     23.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKGYAAFCDADRWFYDAPYRRAEENYPAALAPVPAGWQTHRSGD
                     WLALRPLDARLPSQGWKIHVSACLDNAESVLERVYRYCVERRIAFKFVPSRYLLHLRNA
                     KYADRAASGKFLTVYPADEEQCGRIAEELDALLAGEPGPYILSDLRWNGGPVHLRYGSF
                     TLRHCYDDRGDLVPAIEAPDGRLVPDPRGPVFQTPEWVELPAFLAPHLAERAAVTLEGL
                     PYTVERALHFSNGGGVYAGRDVRTGEPVVLKEARPFAGLAADGADAVTRLDRERRALEQ
                     LAGLDCVPAVHGTFTVGDHHFLVMRYLEGKPLNTYFARRHPLIEADPDPAELAEYTRWA
                     LEIHRRVTEAVEAVHARGIVFNDLHLFNIMVAEDEETGEPSVSLLDFEAAAHVDEGLRQ
                     TVANPAFVAPADRRGVAVDRYALACLRLALFLPLTSLLVLDRGKAAHLADIAAEQFPVP
                     REFLDEAVREILAGAEGAPPAVVPRRPYLPVEPGDWEAARASMTAAIRASATFDRDDRL
                     FPGDTAQFANAGGGTGFGYGAAGVLYALAETGADPWPEAEEWLLARTKEPASGMPLGFY
                     DGLAGIAWTLERLGHRDRALALAEQLLGQPWQSAGPDLHGGLAGIGLALDSLGTATGES
                     ALHAAALRCADLLAESEAAAGSKRAGLLHGHSGPALLHLRLYERTGDRESLLRAGRALH
                     RDLDRCVTSVFGTLQVDEGWRTMPYLGAGSVGIGMVLDDWPAHTPDERFERARPEIVRA
                     AQATFYAQPSLFRGAAGMILHLARTTTPGPGSGPEDIARQVEALARHAVPYQGFLAFPG
                     EQMMRLSMDLSTGTAGALLALGSAAPGGRAQLPFLPPPRSAAAAPEPVPLVGAVSHRNT
                     TVKRNQT"
     misc_feature    complement(12029..12031)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12902..14263
                     /locus_tag="M444_RS30250"
                     /old_locus_tag="M444_30235"
     CDS             12902..14263
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560948.1"
                     /locus_tag="M444_RS30250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30235"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_037798702.1"
                     /transl_table=11
                     /translation="MGRRWAARLSLAAGVAALLVLVVFGGLVSLVLMGVGWAGLALSAA
                     GVWWMLTHTGRIRVLAVLLLVAVPLAVLALYAAAGLLWVVLVSLGLWALAVFAGRAALV
                     EDAPPAMPEHPARRPERPFLIMNPRSGGGKVTKFRLAERARALGAEVVVLDPDRPQDVV
                     QLAREAVRRGADLLGVAGGDGTQALVAGVAVAHDLPFVVISAGTRNHFALDLGLDRKNP
                     ARCLEALTDGVELRVDLGYLRAGGPEEPEEPAEPGTEAVFVNSASFGVYAEVVQSPAYR
                     DDKVRTILEMLPDLLAQESGARLSVRGDGPVLDAPQAVLVSNNPYQRGDSAGLGRRERL
                     DTGELGVLGVHVGSAAEAAELLLRGGQQGRGLTETTAREVVVDADAPVIPVGVDGEALT
                     LPTPVRCRLAPGALRVRVPRHRPGVRLGAPPMDWRRVRRLALTMGRAAAGRGPA"
     gene            complement(14289..15671)
                     /locus_tag="M444_RS30255"
                     /old_locus_tag="M444_30240"
     CDS             complement(14289..15671)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005320966.1"
                     /locus_tag="M444_RS30255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30240"
                     /product="MFS transporter"
                     /protein_id="WP_037798704.1"
                     /transl_table=11
                     /translation="MSDTRTPRRPSGAQRRVLAPLALAQFICSFAGSNMNVMINDISED
                     LDTTVQGVQTAITIFLLVMAALMIPGGKLTDRYGRKRCLLVGLVVYGIGALLSAAAPGL
                     GVLILGNSILEGIGTALLIPPVYILTTLIFTDLASRARAFGVIMALGGIGAAAGPLIGG
                     LITSALSWRAAFVFQALVIAVIILLSRRLEDPLPPDPTRSFDTTGAVLSAAGLILVVMG
                     ILAADDSLWLTLALLALGALVLLGFFRSVRAKERAGKEPLLSTALFRDRTSNLGLVTQN
                     VQWLLLMGSSFTVAAYLQVVRGYDAVQTGVIFTAATLGLLVSSLAAERLAQRWPQRTLI
                     VTGFLATLAGIVVLIALAGSSPNPWALTPGLLLIGLGLGVTLTPSVNVVQSSFPEEQQG
                     EISGLSRSVSNLGSSLGTAVAGTILVAGLSTGAYAAAMIALAVIGLVGLAAALLLPRTP
                     AR"
     gene            complement(15819..17195)
                     /locus_tag="M444_RS30260"
                     /old_locus_tag="M444_30245"
     CDS             complement(15819..17195)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433022.1"
                     /locus_tag="M444_RS30260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30245"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_047960787.1"
                     /transl_table=11
                     /translation="MPEDTAGSGFARLLRELKDRSGLSYGTLAKRLHMSTSTLHRYCTG
                     DVVPTEYAPVERFARLCKASPEELLELHRNWVLADTNRPRRGAGEAEGPARAAAAPATP
                     PSSPSSPSSPSPQESGPGATQEPAPADTAPSAAAAERRRRPRAAALAGIAAGVVAGTIG
                     AVALTAHLTSRDADVRDRPAAAASPAPGAGKRADGRTASPAPSAPSPSASEPAGAGAGS
                     AAPPAPSGSGARSGPASGSGSAPGAPAGDGAVSGTPVKVTAQPYTWESPCGQHYLIEKP
                     PSEVGPPPLERDAPAWVAASRAVSAGEQYVTLTLQGSGKETVVLDGLTVRTVGKHAPLA
                     WNDYAMGYPGVGCGAGVPTRSFTVALDAARPAVVPAPDQPDFPFKVSESEPEVFYVKAD
                     ASKYDVSWYLELSWSSGSRHGTLTIDHNGKPFRTSGLGGRPGYEFPLGGDGWVKAGTTS
                     "
     gene            17409..18161
                     /locus_tag="M444_RS30265"
                     /old_locus_tag="M444_30250"
     CDS             17409..18161
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070308.1"
                     /locus_tag="M444_RS30265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30250"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_078899759.1"
                     /transl_table=11
                     /translation="MSAFRSTPATSTSRATLPRAARRLGGAAALALAALALTACQDGKG
                     LQDEGAATFSDSAVATPSATATPGAGSGSASGSATKTGSATKSGGAKATGGDAKGSSAP
                     SAEGDRVTCNGSNTAVTVQTVSRPLNHMLITVKNTGKKNCDLTYYPVLRFDEMQWAPAA
                     RKDTQPQAVVTLAPGRSGYAGALLSAADGSGEGGVTGHRLTIAFQGRTSHSDGGASAVP
                     SLPAAGVYYDSSLTVTYWQQSASDALGS"
     gene            complement(18156..19568)
                     /locus_tag="M444_RS30270"
                     /old_locus_tag="M444_30255"
     CDS             complement(18156..19568)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949629.1"
                     /locus_tag="M444_RS30270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30255"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_037798707.1"
                     /transl_table=11
                     /translation="MTYISDDRESGPTRRALLVAGAGAALAAGCAPGGTPGAPAPTPSG
                     SAPSGLAAATGPTPGAMTLFKDPGYNFNGLLALGASGAGAAEVGEVLTAVNAINGAGLS
                     AQTYVDTFRKLGDQLLGPPPGSPADAQTKRFRALRAAQYYGQALFFVLGSKDPGSEEQL
                     YKAGRDAWDAFCDLCEPAPVKAAVPYGTTPLPVWFFRPDTSNTPRPTVILTNGSDGQNV
                     DMWTYGVPAALERGWNALVYDGPGQGQLLFVDRVVFTPTWEKVVSPLVDWLSARPDVDQ
                     DRIALTGLSMAGDLAPRAAAFESRIAALVAMPGCVEPWLGFPPEIREILTPSKEETNDI
                     WNTKVVPELPPEAAAVLKKRFEPFSIPAMLQARQGKLFTDFYTPATRIQALSIASVVSR
                     IKAPTLVLDYEDEQFYPGQPRQLYDALTSPKDYLKLTAAQGAQLHCSPMAPQLHCEVVF
                     DWLQETLPGGGS"
     gene            complement(19663..20379)
                     /locus_tag="M444_RS30275"
                     /old_locus_tag="M444_30260"
     CDS             complement(19663..20379)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M444_RS30275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M444_30260"
                     /product="sel1 repeat family protein"
                     /protein_id="WP_037798710.1"
                     /transl_table=11
                     /translation="MRWNGVDFTVDGREPTTAEEFHRIGLHCWQDPRHREAAAFFLEPA
                     ARAGHAEAAELLGHVLFSRGEYAAAAPWLRGSAGTSRRAAHYLGRLSYDGCPPAGITAS
                     YADAAHWYREAARLGEPEAMLALGEMYLERLLPLTGAPVAHALELFAAAAELGHPYAQF
                     RSAELYRTDFAAPDPAARCYELCLANPATATHPLGSLMTQQSRWHLSHIRAAGDAERSG
                     RERDRLHPRPPDEPRY"
     gene            20676..21146
                     /locus_tag="M444_RS30280"
                     /old_locus_tag="M444_30265"
     CDS             20676..21146
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063518.1"
                     /locus_tag="M444_RS30280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30265"
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="WP_037798713.1"
                     /transl_table=11
                     /translation="MSVVKNALPEADLKVVGEALQGALVDLVDLGLVAKQVHWNVVGPR
                     FRSVHLQLDEVVTSARTHSDVVAERASALGITPDGRAATVASSSAISGVPEGWVKDVDA
                     VRILVDGLSAVITRMRERIQATADPDPVTQDILITVTGDLEKHHWMFAAESA"
     gene            complement(21175..21963)
                     /locus_tag="M444_RS30285"
                     /old_locus_tag="M444_30270"
     CDS             complement(21175..21963)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-114). E-value: 6.7e-09. Score:
                     27.8. Matches aSDomain:
                     nrpspksdomains_M444_RS30285_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009062680.1"
                     /locus_tag="M444_RS30285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30270"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_037798716.1"
                     /transl_table=11
                     /translation="MLIDLSGRTALVTGSTQGIGAAIAAGLAAAGARVAVNGRSRASVE
                     EALARLRASGGEFVAAPGDITTDEGARSVFEAVPRTDILVNSLGVFGPAKALEIEDDEW
                     RRYFDTNVLTAVRMIRRYLPGMMERSWGRVQNIASDSAVAVPAEMIHYGMSKTALLAVS
                     RGFAKEAAGTGVTVNSVIAGPTHTGGVEDFVYELVDRNLPWDEAQRAFMRTHRPQSLLQ
                     RLIEPEEIAHMVVYLSSPFASATTGGALRVDGGYVDSILP"
     aSDomain        complement(21622..21939)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M444_RS30285_PKS_KR.1"
                     /evalue="6.70E-09"
                     /label="M444_RS30285_PKS_KR.1"
                     /locus_tag="M444_RS30285"
                     /protein_end="114"
                     /protein_start="8"
                     /score="27.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TALVTGSTQGIGAAIAAGLAAAGARVAVNGRSRASVEEALARLRA
                     SGGEFVAAPGDITTDEGARSVFEAVPRTDILVNSLGVFGPAKALEIEDDEWRRYFDTNV
                     LT"
     CDS_motif       complement(21844..21933)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M444_RS30285_0001"
                     /evalue="6.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="M444_RS30285"
                     /protein_end="40"
                     /protein_start="10"
                     /score="15.6"
                     /tool="antismash"
                     /translation="LVTGSTQGIGAAIAAGLAAAGARVAVNGRS"
     gene            complement(22138..22539)
                     /locus_tag="M444_RS30290"
                     /old_locus_tag="M444_30275"
     CDS             complement(22138..22539)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027199.1"
                     /locus_tag="M444_RS30290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_30275"
                     /product="hypothetical protein"
                     /protein_id="WP_235441287.1"
                     /transl_table=11
                     /translation="MSLPYRTVALPPVDGTVCDPAPPPPQPWTGVVRGVPAGEGEGPGA
                     RVGGREAAAGVETCGLEAEGDAEGLAEAEGEPEPETEAEGEAEALGERNTVGADRATGG
                     FGRVEPATKSTVAMTAVTLAAVQDTHMSR"
ORIGIN
        1 accccgagca gacccggcgg ctcatcgagc ggttcgccgg accgctgggc tactcgcaga
       61 agatgaacgc cgccgcggtc ggtgcggcgc tcgcctcggc cgagatccac cgcaccgagg
      121 aactcagcct gcttcagggg cggctgcggt ccagcatcgc gctgttcgac tcgctggtcg
      181 cgaccgagca gtccgacagc acctacccga tccgggtggt gccgatgacc gacgagacgg
      241 tcatcgacgc cgccaagcag gtcttcgcgg ccgggttcta cacctcgccg gtgttcttcc
      301 cgatcgtcgc ccggggcacc gcgggactgc gcgtgatgct ccgggccggc cagagcgagg
      361 agcagatcag gcggctctgc gcggcgctgg tccgggccgg agcccgcccg gcggccgcgg
      421 cacccgcgcc gggaacgggc ggcgaacacc tcgccgcgac gacaggggaa ggagcgccgg
      481 atggacacgc atgaggacct cggcacggga agcgggcacc cgtggttcgg ccgtcaccgg
      541 ctgcggcccg cagcgcccgc ggacaccatc cggcggatgc tgcggcacga gctccgggac
      601 accggctggc cgtaccagcg ggtcctgccc gcggcgccga tggcgatccc gcgggcgtcc
      661 tacgccgaga tcttccgggt gagcgtcgcg ctgatcgagc tgctgcgccg taccgccctg
      721 gagagcggac ccaccaccgc cgaccggctg agcgcctacg acatgcccgc caccgaggac
      781 cggctgtgga tgggcgaccc cttcgtcgag gagcggtacg ccgactccgt ggtccgtccg
      841 gacctggtca tcggcccgga cgggccgcgg ttcctggagt tcaacgtcag cggcgcgctc
      901 ggtggcgtgg tggagacgcg gagccggctg gcggtgtggc gcgggctcca cgccgacgag
      961 gacggccgga cgccgttccg ctccccggac ccgttcgacg tccgcgcgga catgttccgg
     1021 tcgctcggcg cggagctcgg gctggcgccg cgggtggccg tcgtcggcag cgcccgggtg
     1081 atcggcgtgg agcggcggta cttcgaaatg gaggccgacc actacaacag ccacggcctg
     1141 accgcccgct tcttcgagcc ggaggagctg cccgaggcgt gggactgcgc cccgcacctg
     1201 cgccatcagg tcgggctgcg caacttcacc atcccggact ggctggaggt gggcatcgac
     1261 accacgccgg tccaggacgc cctggacaac ggatgcctgc tggtgggcac ccagacctcg
     1321 accttcatgc acagcaagct gaccatgggg ctgctgtcgg aggggcgccc ctggatgacc
     1381 gcggccgacc gcgggctcgt cgagcggtac ctgccgtgga cgcggatcct ctcggagcgc
     1441 aagaccgacc gggaggggca gcaggtcgac ctgctcccgt tcgtgctggg caaccgggag
     1501 ctgctggtgc tcaaggcggg cctgggggag agcgggaagc aggtcgtcat cggccgcgag
     1561 gtcgaccagg ccgggtggga gtccgccgtc ggcgcggccg tcgccggcgg taccagcgtg
     1621 gtgcaggcct tcgtggagcc gcagacctgc cgggtctcgc tgatcgccga cggctgcgac
     1681 gagccgtacg acgcggatgt cgccccggtc ctcgggcccc tggtgttcgg cggccgcccg
     1741 gccggactgt tctgccggtt cttcggcgac ggcagcgccg ggatcgtcag cgtccgggga
     1801 gggacgagca gctccgacaa cgtgatggtg gctatctgac ggcgccgccc ccgcccggac
     1861 gccccggttt cccgcgccgc cggtgcgaca ctgatggtgt gacgcacggc gaccgggaga
     1921 ctgagcgacg tttggagcgg gccatcctgg agctgctgga gggtcgcggc cccaccgcga
     1981 cgatctgccc gtcagacgcc gcgcgggccg tgtacgcggg cagcgacgac ggctggcgcg
     2041 tgctcatgga accggcccgc cgggcggccc ggaggctggt cggcgcgggc gaggtggaga
     2101 tcacccaggc cggccgcccc gtcgaccccg ctacggcccg cgggccggtc cgtatccgga
     2161 ccgcccgccg acggccgtaa tcagccggcc ggcgggctca gcgtcgggcc gcgaccgccg
     2221 ccagggcgtc cttgacctcc tgcgccacgc gggccgcgtc ctcggggttg ttcaccacgt
     2281 cggtgcggtt catgtcgatg acgaggacgt cactggccga gtagtgcttg tgcacccagt
     2341 cgtcgtagcc ggaccacagc gtccggtagt actcgacgag ggcctcgtcc tgctcgaaat
     2401 cgcggccgcg caggccgatg cggtacatga ccgtctcgaa gtccgccttg aggtagacca
     2461 tgaggtcggg tgccttgcgg tacggcaggc cctcgatctc gcgcatcatc tcgcccagca
     2521 gcccctcgta cacctgcatc tcaagggagc tgatccggcc aaggtcgtgg ttgaccttgg
     2581 cgaagtacca gtcttcgtag atggaccggt cgaggacgtt gtcggcccgg tggtacgcgt
     2641 ccttgatcga ggcgaaccgc gtctggagga agtagagctg gagcaggaag gggtagcgct
     2701 tggcctggat ctcctcgggg ctcgccgtgt agaagagcgg aaggatcggg ttgtcttcca
     2761 cgctctcgaa gaagacctcg ctgcccagct ccttggcgat cagttcggcg acgctcgtct
     2821 tgccgattcc gatcatgcct ccgacgcaga tcactggcat acctcacttc tccctggggg
     2881 tcttctgttc ctgggccggc gcgcggggcg tcccacgtca atgagacgca cgccggcggt
     2941 cacgcgattc cccgggatct tcgtgatcag tgccgtgtgg tcctcgtccg gaccacggct
     3001 ctgaccacgg ccgctctcct cgacgcgcac ggcgacgagc cgcaggtccg cggccgtcct
     3061 gaatcttaag tgatgatccg ccccgtgcgg gccagagcgg gggcggccaa ggccgggcgt
     3121 cagcgccgcc cgccgaactc ccacgggtgg atctcgatgt ccgcgtagcg ctccacgtcc
     3181 aggacgccgc gcgccgcgtc ggcgtccggg gcccggacca gcgccgccgt acccagccag
     3241 gtggtggcgt cgtcggacag cagcgggccg tacgcgatca ggtcgttccg gcagccgggc
     3301 gccgcggtga ggtcggcggc cccgcccgcg ccgaggccga ggaccaggta ccggttgcct
     3361 ccggtccggc caccggggaa gtcccacatg gtgcgcccca gcatgtcgcg ccagcgcagc
     3421 agcagcacgt cccggtacac gccggcctgg tagccgggct cgtcgaaggc gaacgcgcgc
     3481 gcggcggccg gatcggggag gtcgacgatg tgcacgctgc cgctgggggc gtcgccgccg
     3541 ggggcgaagg tcgggccccg ggcgatcagc tccttctcgt actggtccat gtaggaccag
     3601 tggcgttcca gcagttccat gcgcagggcc gtggagccgg ggcgatcgcg gtggtagcag
     3661 aagaattcca tgctgctgga ctctctccga gaaccggctg aagatcaacg gtccggggcc
     3721 ggtgaatgcc gcccggatgc cggggtaggg ggatccgcac cagcccgatc gaggaggtcg
     3781 aagtgagcgt cgaggacccg tccggcaaac gagctcagga gatgcgcgac aaggcgcagg
     3841 agctggagca ggccgcccag tacgccgccg atcccgcgga gcggcagcgg ctcacgcaga
     3901 aggcgctgca catccgcgag aagagcgagc aggtgtacgg cttcggcgcc gggaccatgg
     3961 accccatgta gcccggacac ggccggcggt tcaggtggtc gcgggaggct gcgcgttgac
     4021 cactccgaaa gggacgtgca cgctcggggt gccgtgcgcc gtgccgttca gatgggagac
     4081 ctggtcgtcg aagaagatgt gcgggtcgag ggtgcgcatc accgccgtct tttcgatgcc
     4141 gccgaggaag aaggcgtcgt tgacccgtag cccccagtcc ttgaggctcc gtatggcgcg
     4201 ctcatgggtg ggggcgtccc gagcggtgac cagggacacc cgaaggcgcg gctgatacgc
     4261 gggatcgccg cgccggcgct cctcctcccg gcgctggatg cggttgacgc ccgcgaggaa
     4321 ggggcgcagc ggtcccggat cgtggggggt ggcggcctcg cggacctcgt gcgcgcggaa
     4381 ttcgtcgagt ccgaggctct ggaagacccg ctccgaggcg tcgcccgcca gcactccgtc
     4441 gaagtcgaag gccatgcgga gttcggggtc gctctcgtcg tcgatccgcg ccgtgtggag
     4501 cacgtggccg gcgggcagtc ccgccgcgac cgcgtcccgg acgtcggctc cgttggccga
     4561 caggaacagc gacatgttca gcgcgcgcat gaaggagtgc gaggggcggc cctgccggaa
     4621 caccgcccgg ctgatcggca ggtggtgcgc cgtgatcgac cgcatgaccc gcagcccggt
     4681 gtcggggtcg ttgcgcgaga ggatgatgac ctcgaccagg ggatcggacc ggtccgagag
     4741 gtcgttcagc gacagcaggc gtctgacgaa ggggaaggcc acccccttgg ccagggcgtg
     4801 gtccgcgtgc gcctcctggt aggcccggta ggcgtcctct ccttgctccc ggaacaccgc
     4861 gtcgcagtcg gtcaggtcga acagggcgct ggaggcgatc cccaccacca ggcgactgga
     4921 caggtcgtac cgcatgaagc cccccgttga acgcgatcgg aacgatgggg ggcttatcgc
     4981 cctccggcat atgcggaaaa cgtccgccgg ggtgattctg aggtcccgga cgggccctcg
     5041 gcggcccccg ggcggtgtgc ggagccgcac ccatgcgggc ggaatcagcc catccggttg
     5101 ttgggtccgc gccccggcgg gcgggggttt cgcgatgact gccgaggtcg ggcggccgtg
     5161 ggccgtgcgg gagcggcggg aggcgggcgt caggcttcgg ccacccgctc ccgcgcgccg
     5221 catgccgtga cgttcccgca cggcactggc tgggcagccg gttggtgctg attgatcgtc
     5281 acgtgagggg aaccgcgatg accaaggttc tggtgctgca cagcgtgtgt ctggtgaggt
     5341 ccgccctcgc cgcgctgctg agaaccgagg gtgacttcga tgtcacctcc tgcggctggc
     5401 gcgccgccgg gcgccaggcg gcgtccttac ggcccgacgt ggccgtggtg gacctcgact
     5461 gtccgggggc gtcggcggcc ctgctcgcgg acgccgacgc cgctcgtccg ttcccgcgct
     5521 ccacgccgct gctcgtcctc gcccgcgccg acacccccgg ctcgctgcgg cgcgccttcc
     5581 tgacccaggc gcagggttac gtcgacaagg acggctcgcc cgcccggctg gtccgggcca
     5641 tcggcagggt cgcggccggg gaacgctcca tcgacgccac gctcgcctcg gccttcatgg
     5701 aggccgaccc catgccgctc agcccgcgcg agctgagcgt gctggcccgg gccgccgagg
     5761 gcgactcgat cgcggagata gcccgcgccc tgcacctcgc cagcggaacc gtacggaact
     5821 acatggccgc cgtgacgcgg aagaccggcg cccgaaaccg gatcgatgcc atccggattt
     5881 cccggcgggc cggctgggtc tgagaccccg gcgccggttc cccccaagcc cgcttcaccc
     5941 ccgcgcgttc cacagaccca ccagatcccg gtacagcggc gacctggcgg ggagctccgc
     6001 atgcgtgccg cacaccgccc gggtcccgtc gagtacgagg acccggtcgg ccctggcggc
     6061 ggaggagatg cggtgggcga ccaccaccag ggtcccgggg cgcgcggcga gcgcccgctc
     6121 ggcgcgttcc tccgtccgga ggtcgaggtg gcaggtggcc tcgtccagca ggagcagcgg
     6181 ggcgggggag aggtaggcgg cggtgagggc gaggtgctgg cgctcgcccg gcgagagccg
     6241 ggccgggtcg acagccccgt ccagcccgcc gagccggtcc acgagcccgt ccgagccgag
     6301 ggcggccgtg gcccgctcca cctcggcccc ggataccggg ccggggcaca ggtgggtcag
     6361 gttctcgcgg accgtccccg tgaacacgta cgcctgctgg ggcaacaggg tccgccgaag
     6421 atcgggcccg ggcccggtga cgccctgcgc gggggcaccc gccacccgta cggttccccc
     6481 gccgggcggc agcaggccgg cgatcagagc ggtgagcgtg gactttccga tgccgctcgg
     6541 ccccaccacg gccaggtgct cgcccgcccc gaccgtcagg tcgagcccgt cgatcaccgg
     6601 ctgcgcgcgg gggccgtagg cgaaccacac cccccgcagc tcaacggcga cacccggccc
     6661 ggcccccacc ccgggggcca ccgccggggc cgtggtcgcg gcggcggagt ccgattgggg
     6721 cgcgcagaag cggtccagta ccaccaggag ccgggtgccc gccgcgccca ccgccgtcat
     6781 cagggcgtcc agggcgggca gcagcgactg cacgaggtag gtgagggccc cggccaccgc
     6841 ccccgcgctc accccgcggc cgagcagcca cggcgtcccg gccagcagcg cgacgaccgg
     6901 caaccggccg gcgacgccca gggccagcgt gcgcagggcg ctccagcgcg cgaggcgccc
     6961 ggtcagccgc tcctgctcgg cgatcagccg ctccaccggg gctccggcgc tcgccccgcc
     7021 gccgcaggcg acgacgtcgc gcagccccgc cgccagttcg ccggcgcgcc cggacagcgc
     7081 ctcgtcggcg tcgagcgccg cccgctgcac gcgcgccatc gggcgcaacg tggccaggaa
     7141 cccggccgta cccaggagca gcgcgggcag tacgaggacc agcaggacgg gatccagcgc
     7201 ggccagcccc agcagcgccc ccagggcggt gaagacgaac gaccgggcga ccaggaccag
     7261 tccggcgaag gagtcgcggg ccatctcggt ctgctgcgtg agccgggaga cggcgcccgc
     7321 gtcaccggcc cgcccggggt cggcgacggc ccgcccgatc gcctggcgta cggaacgccg
     7381 caccaggccg tcccgcaggg gctcgaccag gtcggcgagc ccgccgaaca ctccgcgcag
     7441 ggcgagggcg ccgagcaggg cccccgcgcc ggccacggcc agccagccga gtccggtgcc
     7501 ggtgcgcccg gcgaggaagc cgtcgtcgag ggcgcgggcg accgcgtagc cgccgaggaa
     7561 ggtgtgcgcg gactccagca gggaccagag cgcgagccgc cgcagcgacc ggtaccgccc
     7621 gcgcaggaag cggcggccct cgcgcgacac cctgcgccag gagccgtccc cgctcatcgg
     7681 accgtctccc ggccgggcgc ccgccgcccg ccgccgcccg ccgcggccga tcccgttccg
     7741 gcactcgctc ccgcgtccgg cccttcgccc ggcgccgcac ccgttcgcgg gctcgctgcc
     7801 gccaccggct ccgagcccgt tccttcggcc cgtgccgggg ccgcgcctgc tgccgcgtcg
     7861 gagccggtgt tccgctgcgc gtccggcctt ccggcggcag gcggtaccgg tgccgccgcg
     7921 gactccgtgt ccggttccga ggccgttcct tcggcccagg cccgggccgc gcccgttgcc
     7981 gcgtcggagt ccgtgttccg ctgcgcgtcc gggcctccgg cggcaggcgg taccggtgcc
     8041 gccgcaggct gcgtgttcgg ggggtcggcc ggttccgtgc cggtggcgaa caccgcgcgg
     8101 taggccgggt ctcgccagag ctccgtgtgg gggccggtcg cgcggacgcg tcccgcgtcg
     8161 agccagacga cgaggtccgc gcgggcggcc gcggagatgc ggtgggcgac gacgaggcgg
     8221 gtgcccgggc ggacgtcgtg ggtcagggcg cgctccacct cccgggcggt gagggtgtcc
     8281 aggctcgacg tcgcgtcgtc caggacgagc agccgcccgg cgcggcagaa cgcccgggcc
     8341 aggcccagac gttgcagctc cccgccggac agtggcgcgt ccggcagcgc cgtgtcgtag
     8401 ccgtcgggca ggcggcgtac gaaggcgtcc gccccggccg cccgcgccgc ggcgcgtacg
     8461 ttctccgggg gcggcgccgg cccgctgccg aacgcgatgg cggccgcgac gtcctccccg
     8521 aacagggcgg gccgctcgaa ggcgtggccg acctcccggc gcagctcccc ggcggacagt
     8581 tcgtccagcg gtacgccgtc cagcaggacc cgccccgcgt cgcaggcggt gagccggccc
     8641 gccaccgcgg ccagcgtcgt cttgccggag cccgagcggc cgacgacggc cgcggtcgtc
     8701 ccgccgggga tccgcaggtc gatgtcgcgc agcaccgcgg tgcccccgcg gacgacccgc
     8761 accccgcgca gctccagcgc gcccggcccg cccggcggca accggcttac cccctggggg
     8821 agttccggca gttcgaagag ggccgcggtg cggcgcgcgg cggcgcggcc gcgcaccacc
     8881 gccgccagcc gccccgtcac ggcgccgacc ccggccgcga gtcccgcgta gcggaccgcg
     8941 gcgaggagcc cgccgacgcc gagggccccc tcggcgaggc ggatcccgcc cacgccgagg
     9001 acgacgtaca gcagcagcgg catcagggcg cccgtgcgcg ccatggtcgt gccgtagatc
     9061 cgccaggtct cccgcccctc ggcgccgagt tccggcaacc ggcgcagcac gcgtgcctgt
     9121 tcgcgttcgg cggtgccggc ggcggcgatg gtacgggcgc ccgcgagggc ctccacgagg
     9181 cggccggcca tcgcgagctg gacttcctgg taacggccca cactcgcccc cgagtcgcgg
     9241 gcgaacgccc tcaacagcag cgccagcaag gggagtccgg cgaggaacgc cagcgcggtc
     9301 catacgtcga ccaggaccag cgccacgagt ccgccgagcg gcgccagcag ggccacggcc
     9361 gcgcccacca cggccgccgg tacggcgccg gcggtggtgg cctgggcggt cagccgggcg
     9421 gagagctcac cgggggagtg gcgggcggcg tggtgcggcg cggcccgcag cagccggccc
     9481 agtcccagcc gccgcagcca ggccgtggag cgggcgtcga cgccgccggt gaggcgggcc
     9541 gtcaccgcgt cgagcagtac ctcggcggcg atcaccgccg cgcaccacgc ggtccaccgg
     9601 gcgccgccgg gatcctgtcg cagcagcagg tcgagggtgt ggccgaggac cgccggttcg
     9661 gccagggccg cgccggcggc ggccaccgaa cagacggcgg cggcggcgag acggccgccg
     9721 ctgtgtcgtg cggccgcccg cagcgcccgg tcggcgccgc gggcggcctc cgcctcacgg
     9781 gtgggatcgg gtgcggtcat gggcgacggc tccaggggtg tggtgcgggc ccgggcggag
     9841 aaccgcccgg gcccgatagg acctgactag ttacaggtcg tgatgctcag gctgctgtcg
     9901 ccgcagagga gcaggctggc gcggctgccg ccaccgccac cgtgcgcggc ctcggtggtc
     9961 tcttccttcg gggtttccat cgactgcagg tcgagaagcg tcatgtctga ttcctcttca
    10021 ctgtggtgtt ccgatgggac acggccccca cgagggggac cggctctggg gccgccgcgg
    10081 ccgaccgcgg cggcgggagg aacggcagct gtgcgcgccc gccgggcgcg gcgctgccga
    10141 gggcgaggag cgcgccggcc gtgcccgtgg acaagtccat ggacaggcgc atcatctgct
    10201 cgccggggaa ggccaggaag ccttggtacg ggaccgcgtg ccgggccagg gcctccacct
    10261 gccgggcgat gtcctccggg ccggagcccg ggcccggggt ggtggtgcgc gccaggtgga
    10321 ggatcattcc ggcggcgccg cggaacaggc tcggctgcgc gtagaacgtg gcctgcgcgg
    10381 cgcggacgat ctccggccgg gcccgttcga agcgctcgtc cggggtgtgg gccggccagt
    10441 cgtccagcac catgccgatc cccacgctgc cggccccgag gtagggcatc gtgcgccacc
    10501 cctcgtcgac ctggagggtg ccgaagacgc tggtcacaca gcggtcgaga tcgcggtgca
    10561 gggcccggcc ggcccggagc agtgactccc ggtcgccggt gcgttcgtag agccgcaggt
    10621 ggagcagcgc gggtccgctg tggccgtgga gcagaccggc ccgtttcgag ccggcggcgg
    10681 cctcggactc cgcgagcaga tcggcgcagc gcagggccgc ggcgtgcagt gcgctctcgc
    10741 cggtggccgt gcccagggag tccagggcca gcccgatgcc cgccagtccg ccgtgcaggt
    10801 cggggccggc cgactgccag ggctggccca gcagttgttc ggcgagggcg agcgcgcggt
    10861 cgcggtggcc gagccgctcc agggtccacg cgataccggc gaggccgtcg tagaagccca
    10921 gcggcatgcc ggaggccggt tccttcgtcc gggccagcag ccattcctcg gcttcgggcc
    10981 acgggtcggc gccggtctcg gcgagcgcgt acagcacacc ggcggccccg tagccgaaac
    11041 cggtgccgcc gccggcgttc gcgaactggg cggtgtcccc ggggaagagg cggtcgtcgc
    11101 ggtcgaaggt ggcgctggcc ctgatcgccg ccgtcatcga ggcgcgggca gcctcccagt
    11161 cgcccggctc gaccggcaga taggggcggc ggggcaccac cgcgggtggg gcgccctccg
    11221 ccccggcgag tatctcccgt accgcctcgt cgaggaactc gcggggtacg gggaactgct
    11281 cggcggcgat gtcggccagg tgcgcggcct tgccccggtc cagcaccagc aggctggtca
    11341 gcggcaggaa cagggccagg cgcaggcagg ccagggcgta ccggtcgacg gcgacgccgc
    11401 gccggtccgc cggggcgacg aacgccgggt tggcgacggt ctggcgcagc ccctcgtcga
    11461 cgtgcgcggc ggcctcgaag tcgaggagcg acaccgacgg ctcgccggtc tcctcgtcct
    11521 ccgcgaccat gatgttgaac aggtgcaggt cgttgaagac gatgccccgg gcgtgcaccg
    11581 cctccacggc ctccgtcacc cgccggtgga tctccagcgc ccaccgcgtg tactccgcga
    11641 gctccgcggg gtcggggtcc gcctcgatca gcgggtgccg gcgggcgaag taggtgttga
    11701 ggggtttgcc ctccaagtac cgcatcacca ggaagtggtg gtccccgacg gtgaaggtgc
    11761 cgtgcaccgc gggcacgcag tccagcccgg ccagctgctc cagggcccgg cgttcgcggt
    11821 ccagccgggt cacggcgtcc gccccgtcgg ccgcgagccc cgcgaagggg cgcgcttcct
    11881 tgaggacgac cggctcgccg gtgcggacgt cacggccggc gtagacgccg cccccgttgg
    11941 agaagtgcag ggcccgctcg acggtgtagg gcaggccttc gagggtgacg gccgcccgct
    12001 cggccaggtg gggcgccagg aacgcgggta actcgaccca ttccggagtc tggaacaccg
    12061 gcccccgcgg gtccggaacc agccggccgt ccggggcctc gatcgcggga acgagatcgc
    12121 cgcggtcgtc gtagcagtgc cgcagcgtga agctgccgta ccgcaggtgc acgggaccgc
    12181 cgttccagcg caggtcgctc aggatgtacg ggccgggctc gccggccagc agcgcgtcga
    12241 gctcctcggc gatgcgcccg cactgctcct cgtccgccgg gtagacggtg aggaacttgc
    12301 cgctcgcggc gcggtccgcg tacttcgcgt tgcgcaggtg caacaggtac cggctcggaa
    12361 cgaacttgaa ggcgatccgc cgctccacgc agtaccggta gacccgttcg aggaccgact
    12421 cggcgttgtc gaggcaggcc gagacatgga tcttccagcc ctgcgagggc agtcgggcgt
    12481 ccagggggcg cagcgccagc cagtccccgc tgcggtgcgt ctgccacccc gccggtacgg
    12541 gggcgagcgc ggccgggtag ttctcctcgg cccgccggta cggcgcgtcg tagaaccagc
    12601 ggtcggcgtc gcagaaggcc gcgtacccct tgttcactcc tgctccctcg gtcggtgacg
    12661 tgctcacgct gtcacgcggc ccgagggccg cgacagtcac ggctgtcact tccggggtgt
    12721 gcagtacgca cgagtcacaa cgggccgccc atgctctcga tcggcgcgat cgccgcgacc
    12781 gggcggaaac aaaccgggcc cggaccgccg ggtcccgcgg gccgggtggg ggtggcgctc
    12841 gtaggctgaa gagggtgtac ggctcctgtc cggcagccgg tgggccgcgg gaaggtgagg
    12901 catgggaagg cgctgggccg cacgtctgtc actggccgcg ggtgtggcgg cgctgctggt
    12961 gctggtggtc ttcggcgggc tcgtcagcct cgtgctcatg ggcgtgggct gggcggggct
    13021 ggcgctctcg gctgcgggcg tgtggtggat gctcacccat accggccgga tccgggtgct
    13081 ggccgtgctg ctgctggtgg ccgtgccgct cgccgtgctc gccctgtacg ccgccgcggg
    13141 gctgctgtgg gtcgtgctgg tctcgctcgg cctgtgggcg ctggccgtct tcgcgggccg
    13201 ggccgcgctg gtcgaggacg ccccgccggc catgcccgag caccccgccc gcaggcccga
    13261 gcggccgttc ctgatcatga acccgcgctc gggaggcggg aaggtcacca agttccggct
    13321 cgccgagcgg gccagggccc tgggggccga ggtcgtcgta ctggatccgg accggccgca
    13381 ggacgtggtc cagctggcgc gggaggccgt ccggcgcggc gccgacctgc tcggcgtcgc
    13441 gggcggtgac gggacccagg ccctggtcgc cggggtggcc gtggcgcacg acctgccctt
    13501 cgtggtgatc agcgccggca cccgcaacca cttcgccctg gacctgggcc tggaccgcaa
    13561 gaaccccgcc cggtgcctgg aggcgctgac cgacggcgtc gaactgcgcg tcgacctcgg
    13621 atacctccgg gcggggggtc ctgaggagcc cgaggagccg gcggagcccg gtacggaggc
    13681 cgtcttcgtc aacagtgcct cgttcggcgt gtacgcggag gtggtgcaga gccccgccta
    13741 ccgcgacgac aaggtccgca ccatcctgga gatgctgccc gacctgctgg cccaggagag
    13801 cggcgcgcgg ctgagcgtgc gtggcgacgg gccggtcctg gacgcccccc aggccgtcct
    13861 ggtgagcaac aacccctatc agcggggcga ctcggcggga ctcgggcgcc gggagcggct
    13921 ggacaccggc gagctggggg tgctgggcgt ccacgtcggc agcgccgccg aggcggcgga
    13981 gctcctgctg cgcggcgggc agcagggccg cgggctgacc gagaccaccg cccgggaggt
    14041 cgtcgtcgac gccgacgccc ccgtcatccc ggtcggtgtc gacggggagg ccctgacgct
    14101 gcccactccg gtccgctgcc gcctcgcgcc cggcgccctg cgcgtccgcg tgccccggca
    14161 ccggccgggc gtacggctgg gcgcgccgcc gatggactgg cgccgggtgc ggcggctggc
    14221 gctgaccatg ggtcgggccg ctgcgggccg cggtcccgct tgaccgggcg agagcggggg
    14281 aggggcggtc accgcgccgg agtccgcggc aggagcagcg cggccgcgag cccgacgagc
    14341 ccgatcacgg ccagcgcgat catcgcggcg gcgtaggcgc cggtggagag gcctgcgacg
    14401 agaatggtgc ccgcgaccgc cgtgccgagg gaggaaccga ggttcgacac gctgcgggag
    14461 aggccggaga tctcgccctg ctgctcttcg gggaagctcg actggacgac gttgaccgag
    14521 ggggtcagcg tcacgccgag acccagtccg atcagcagga ggccgggcgt gagcgcccac
    14581 gggttcgggg agctgccggc cagcgcgatc aggacgacga tgccggcgag ggtggcgagg
    14641 aaacccgtca cgatcagggt ccgctggggc caccgctggg cgaggcgttc ggcggcgagc
    14701 gaggacacga gcaggccgag cgtggcggcg gtgaagatga caccggtctg gacggcgtcg
    14761 tagccgcgta cgacctggag gtaggccgcc acggtgaacg aggaccccat cagcagcagc
    14821 cactggacgt tctgcgtgac caggcccagg ttggacgtcc ggtcccggaa cagggccgtg
    14881 gacagcagcg gttccttgcc cgcccgctcc ttggcccgca cggagcggaa gaacccgagg
    14941 agcacgaggg cgcccagggc gagcagggcg agggtgagcc acaggctgtc gtcggccgcg
    15001 aggatgccca tgacgacgag gatcaggccg gcggcggaga ggaccgcgcc cgtggtgtcg
    15061 aaggagcggg tcggatcggg cggaagcgga tcctccaggc ggcggctcag caggatgatc
    15121 acggcgatga ccagggcctg gaagacgaag gcggcccgcc agctcagcgc cgaggtgatc
    15181 agcccgccga tgagcggccc ggcggccgcg ccgatgccgc ccagcgccat gatgacgccg
    15241 aaggcccggg cccgggaggc gaggtccgtg aagatcagcg tcgtgaggat gtagacgggc
    15301 gggatgagca gggccgtccc gatgccctcc aggatcgagt tcccgaggat cagtacgccc
    15361 aggcccgggg cggcggcgct cagcagcgcg ccgatgccgt agacgacgag gccgaccagg
    15421 aggcagcgct tgcggccgta gcggtcggtc agtttgccgc cggggatcat cagcgcggcc
    15481 atgaccagca ggaagatcgt gatggctgtc tgtaccccct ggacggtcgt gtccaggtcc
    15541 tcgctgatgt cgttgatcat cacgttcatg ttggagccgg cgaagctgca gatgaactgc
    15601 gcgagcgcca gcggcgcgag gacccgccgc tgcgcgccgg acggccggcg cggggttcgg
    15661 gtgtcggaca ccggtgtcgc ctccgcatct cgggccgccg ggcctgctgc gcggcggttc
    15721 gtacgcggtg ccgcccttgg cggtacgcac ccacgctcac agcgtgcgcc gtgccggggc
    15781 ggggcgcacg ccgagtgccc ggcacgcgtc cggaacggtc agctcgtcgt accggccttg
    15841 acccagccgt cgccgccgag ggggaactcg tagcccgggc gaccgcccag tccgctggta
    15901 cggaacggct tgccgttgtg gtcgatcgtg agggtgccgt ggcgggagcc gctggaccag
    15961 gacagctcca ggtaccagct cacgtcgtac ttggaggcgt cggccttgac gtagaacacc
    16021 tccggttcgg actcgctgac cttgaacggg aagtccggct ggtcgggcgc gggcacgacg
    16081 gccgggcgcg cggcgtcgag ggccacggtg aacgaccggg tcggtacgcc ggcgccgcag
    16141 ccgacacccg gatagcccat ggcgtagtcg ttccaggcga ggggcgcgtg cttgccgacc
    16201 gtacggacgg tcaggccgtc caggaccacc gtctccttgc cggagccctg gagggtgagc
    16261 gtgacgtact gctcgcccgc ggagacggcc cgggacgccg ccacccaggc gggcgcgtcc
    16321 cgttccaggg gcggcgggcc cacctcggac gggggcttct cgatcaggta gtgctggccg
    16381 cagggcgact cccaggtgta cggctgggcg gtcaccttca ccggggtccc ggacacggcg
    16441 ccgtcgccgg cgggggcccc gggcgcggac cccgaccccg acgcgggccc ggatctggct
    16501 ccggacccgg acggggccgg gggtgcggcg ctgccggcgc cggccccggc gggctcggag
    16561 gccgacgggg agggcgccga gggcgcgggg gaggccgtcc ggccgtccgc gcgcttcccc
    16621 gcgccgggcg cgggggacgc ggccgcggcg ggccggtcgc ggacgtcggc gtcccgtgac
    16681 gtcaggtgcg cggtgagggc tacggccccg atcgtcccgg ccacgacgcc cgccgcgatc
    16741 ccggcgagag cggccgcgcg cggacggcgc cgccgctccg ccgcggccgc cgagggcgcg
    16801 gtgtcggcgg gcgcgggctc ctgcgtcgca cccggcccgc tctcctgcgg agatggcgac
    16861 gacggagacg acggagacga cggcggtgtc gccggggcgg cggcggcccg tgccgggccc
    16921 tccgcttcac cggcgccccg gcgcgggcgg ttcgtgtccg ccagcaccca gttccggtgc
    16981 agttcgagga gttcctcggg cgaggccttg cagaggcggg cgaaccgctc gaccggtgcg
    17041 tactccgtcg ggacgacatc gcccgtgcag tagcggtgca gggtcgacgt actcatgtgg
    17101 agccgtttgg cgagcgttcc gtagctgagg ccggaccggt ccttcaactc ccgcagcagc
    17161 cgggcgaacc cggacccggc agtgtcctcc ggcaccgatc ctcctacccc cgtgtcccgt
    17221 ccggcgtccc aggaacgggt tgttccagca gctcagagcc cgtttcggcg tcccaccgtc
    17281 cctgaccgcc cccggcgggt ggcggctggg acggatcacc gcacaggctg aggccatcca
    17341 agcacaccgc tcacggcgac cggtcccgac cgtccgccgc agccacgtca catgaggggt
    17401 cctcagccat gtccgccttc cgcagcaccc ccgccacgag cacctcccgc gccacccttc
    17461 cccgcgccgc ccgccggctc ggcggcgcgg ccgcactcgc cctcgcggcc ctcgccctga
    17521 ccgcgtgcca ggacggcaag ggcctccagg acgagggagc cgcgaccttc tcggactccg
    17581 ccgtcgccac tccctcggcg acggccaccc cgggggccgg ctccggatcg gcctccggat
    17641 cggccacgaa gaccggttcc gccacgaagt ccggcggggc gaaggcgacc ggcggcgacg
    17701 cgaagggctc ctccgccccc tccgccgagg gcgaccgcgt cacctgcaac gggtccaaca
    17761 ccgccgtcac cgtccagacg gtctcccgtc cgctcaacca catgctgatc acggtgaaga
    17821 acaccggcaa gaagaactgc gacctcacgt actaccccgt gctccgcttc gacgagatgc
    17881 agtgggcgcc ggccgcgcgg aaggacaccc agccccaggc cgtggtcacc ctcgcacccg
    17941 gccggtccgg ctacgccggg gccctgctgt cggcggccga cggcagcggc gagggcgggg
    18001 tgaccggaca ccggctcacg atcgccttcc agggccggac gtcccacagc gacggcggcg
    18061 cgtccgccgt cccgtcgctg ccggcggcgg gcgtctacta cgacagctcg ttgacggtca
    18121 cctactggca gcagagcgcc tcggacgcac tcggctcatg agccgccgcc cggcagggtc
    18181 tcctggagcc agtcgaagac gacctcgcag tgcagctgcg gggccatggg ggagcagtgg
    18241 agctgggcgc cctgggccgc ggtcagcttc aggtagtcct tgggagaggt gagcgcgtcg
    18301 tacaactggc gcggctggcc ggggtagaac tgctcgtcct cgtagtccag gacgagggtg
    18361 ggcgccttga tccggctgac gacggaggcg atcgagagtg cctggatacg ggtggcgggg
    18421 gtgtagaagt cggtgaagag cttgccctgc cgggcctgga gcatcgccgg gatggagaag
    18481 ggctcgaagc gcttcttcag cacggcggcg gcctccggcg gcagctcggg aacgaccttc
    18541 gtgttccaga tgtcgttcgt ctcctccttg ctgggggtga ggatctcccg gatctcgggc
    18601 gggaagccca gccagggctc gacgcagccg ggcatggcca ccagcgcggc gatccggctc
    18661 tcgaaggccg ccgccctcgg cgcgaggtca cccgccatgc tcagaccggt cagggcgatc
    18721 ctgtcctggt ccacgtccgg gcgggcggac agccagtcga cgagggggct gacgaccttc
    18781 tcccaggtgg gggtgaacac cacccggtcg acgaagagca gctgcccctg ccccggaccg
    18841 tcgtagacga gggcgttcca gccgcgttcg agcgcggcgg ggaccccgta ggtccacatg
    18901 tcgacgttct ggccgtcgct gccgttggtc aggatcaccg tgggccgggg cgtgttcgac
    18961 gtgtcgggcc ggaagaacca caccggcaac ggcgtcgtgc cgtacgggac ggcggccttg
    19021 accggggcgg gctcgcacag gtcgcagaag gcgtcccagg cgtcccgtcc cgccttgtac
    19081 agctgctcct cgctgcccgg gtccttggaa ccgaggacga agaacagcgc ctggccgtag
    19141 tactgggcgg cgcgcagcgc ccggaaccgt ttggtctggg cgtcggccgg tgagcccggc
    19201 ggcggcccca ggagctggtc gccgagcttg cggaaggtat cgacgtacgt ctgcgcggag
    19261 aggccggccc cgttgatcgc gttcacggcg gtgaggacct cgccgacctc ggcggcgccg
    19321 gcgccggagg ccccgagcgc gaggaggccg ttgaagttgt accccgggtc cttgaagagc
    19381 gtcatcgcac cgggggtggg gccggtcgcg gccgcgaggc cggagggagc ggagccgctg
    19441 ggggtgggcg ccggggcgcc gggggtgcct ccgggagcgc agccggcggc gagcgccgcc
    19501 ccggcgccgg cgacgagcag ggcgcggcgg gtgggaccgg actcccggtc gtctgatatg
    19561 tacgtcatat cagtggaacg tagccctggt ccggtacacc cacattccga cctgctccga
    19621 acggcttacg gcctacggct tgtggcttgc cgtcggcggc ggtcagtagc ggggctcgtc
    19681 cggtgggcgg gggtggagcc ggtcgcgctc ccggccggag cgctccgcgt ccccggcggc
    19741 gcggatgtgg ctcaggtgcc accggctctg ctgggtcatc agcgagccga gcgggtgggt
    19801 cgcggtggcc gggttcgcca gacacagctc gtagcagcgg gccgccgggt cgggcgccgc
    19861 gaagtcggtc ctgtacagct cggcgctgcg gaactgggcg tacgggtggc cgagttccgc
    19921 ggcggcggcg aacagctcca gggcgtgcgc cacgggagcc ccggtgagcg gcagcagccg
    19981 ttccaggtac atctcgccga gcgccagcat ggcctccggc tcgccgagcc gggcggcctc
    20041 gcggtaccag tgcgcggcgt ccgcgtagga ggcggtgatg ccggccggcg ggcagccgtc
    20101 gtaggagagc cggccgaggt agtgggcggc ccgccgggag gtgccggcgc tgccgcgcag
    20161 ccagggcgcc gccgcggcgt actcgccccg ggagaacagg acgtgcccga ggagttcggc
    20221 cgcctcggcg tgaccggcgc gggccgcggg ttcgaggaag aacgcggcgg cctcccggtg
    20281 ccgcggatcc tgccagcagt ggagcccgat ccggtggaac tcctccgccg tggtgggctc
    20341 ccgcccgtcc acggtgaagt cgacgccgtt ccacctcacc ccgtcccgcc cccgtccccg
    20401 cggcgcgcgc cgctccgtac ccgtggtccc cgccgccggt tcgcgggccc gaccccgttt
    20461 accgtacgcg gcagcggcca catgcgggcc atggccgaac cggagaagag ggcccccgac
    20521 cggccttccg cgccggcgaa ccggcctcgt gcggtggccg cgcggctcga ctggacgggc
    20581 aggcgaacgt tttgtccggg accctcaggg taggcgccgt ttcgtccgca gtcatccagt
    20641 cgaacaatca agcaacaccg aggaatggag acgtcgtgtc cgtcgtcaag aacgccctcc
    20701 cggaagccga cctgaaggtc gtcggcgaag cgctccaggg cgctctggtg gacctggtgg
    20761 acctgggcct cgtcgccaag caggtccact ggaacgtggt cggcccccgc ttccggtccg
    20821 tgcacctcca gctggacgag gtcgtcacct cggcgcgcac ccactccgac gtggtcgccg
    20881 aacgtgcctc cgccctcggg atcaccccgg acggccgggc cgcgacggtg gcgtcgtcga
    20941 gcgcgatcag cggggtgccg gagggctggg tgaaggacgt ggacgcggta cgcatcctcg
    21001 tcgacggcct cagcgcggtg atcacccgca tgcgcgaacg catccaggcc accgcggacc
    21061 ccgacccggt cacccaggac atcctcatca cggtgaccgg cgacctcgaa aagcaccact
    21121 ggatgttcgc cgccgagagc gcctgagcgg gcgccggggg gtgggcgcgg gcggctacgg
    21181 gaggatggag tccacgtagc cgccgtccac tcgcagggcg ccgcccgtgg tcgcggaggc
    21241 gaagggggag gacaggtaga ccaccatgtg ggcgatctcc tccggctcga tcagccgctg
    21301 gagcagcgac tgggggcggt gcgtgcgcat gaacgcgcgt tgcgcctcgt cccacggcag
    21361 gttccggtcg accagttcgt agacgaagtc ctcgacgccg ccggtgtgcg tcgggccggc
    21421 gatgacggag ttcacggtca cgcccgtgcc cgcggcctcc ttggcgaagc cccgggacac
    21481 ggcgagcagg gccgtcttgg acatcccgta atggatcatc tcggcgggga cggccaccgc
    21541 cgagtcgctg gcgatgttct ggacgcggcc ccaggagcgc tccatcatgc ccgggaggta
    21601 ccgccggatc atccggacgg cggtgagcac gttcgtgtcg aagtagcggc gccattcgtc
    21661 gtcttcgatc tccagcgcct tcgccggtcc gaagaccccg aggctgttga cgaggatgtc
    21721 ggtccggggg accgcctcga agacggaccg cgcgccctcg tccgtcgtga tgtcgccggg
    21781 cgccgcgacg aactcgccgc ccgacgcgcg gaggcgggcc agcgcctcct ccacggatgc
    21841 tcggctgcgg ccgttgacgg ccacccgggc gcccgcggcg gccaggccgg cggcgatggc
    21901 cgcgccgatc ccctgtgtgg agccggtgac cagggccgtc ctgccggaga ggtcgatgag
    21961 cacgcgatac ccgcctcgtc tgccgccgcg cggcccgtcg ggtccgccgt cctcgtcacg
    22021 ggttccccgt atcggcggat tcctcacctt ccgcccggga gacggccctc accgcggctg
    22081 cccttgccgg gcccggctcc gtcactatgg gggcgtgcac cgcttccgct tcccgcgcta
    22141 cctgctcata tgggtgtcct gtacggccgc cagcgtgacc gccgtcatgg ccaccgtcga
    22201 cttcgtggcg ggctcgacac ggccgaaacc gccggtcgcg cggtcggcgc cgaccgtgtt
    22261 cctctcaccc agtgcctcgg cttccccttc cgcttccgtt tccggttccg gctcgccctc
    22321 cgcctccgcg agcccttccg cgtcgccctc ggcctccagc ccgcaggtct ccactcccgc
    22381 ggccgcctcc cgtccgccga cgcgggcgcc cggcccctcc ccctcaccgg ccggcacacc
    22441 ccgtaccacc ccggtccagg gctgcggtgg cggcggggca gggtcgcaca ccgtcccgtc
    22501 gacgggcggc aaggcgaccg tgcggtacgg gagcgacaag gtgtgcctga tctccgcggt
    22561 cccggcgctc ggcttcaagg tgagcaccgc ccagaacgcg gaccacacgc tcaccgtcac
    22621 gttcaccggc agcggtc
//
