LOCUS       NZ_CP011664            21074 bp    DNA     linear   CON 03-MAR-2024
DEFINITION  Streptomyces sp. Mg1 chromosome 1, complete sequence.
ACCESSION   NZ_CP011664
VERSION     NZ_CP011664.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. Mg1
  ORGANISM  Streptomyces sp. Mg1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     De Novo Assembly of the Streptomyces sp. Strain Mg1 Genome Using
            PacBio Single-Molecule Sequencing
  JOURNAL   Genome Announc 1 (4), e00535-13 (2013)
   PUBMED   23908282
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUN-2015) Biochemistry and Biophysics, Texas A&M
            University, 300 Olsen Blvd., College Station, TX 77845, USA
REFERENCE   3  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JUN-2013) Biochemistry and Biophysics, Texas A&M
            University, 2128 TAMU, College Station, TX 77843, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 8.2
            Genome Coverage                   :: 30X PacBio; 80X Illumina
            Sequencing Technology             :: PacBio + Illumina MiSeq/HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 08:10:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,822
            CDSs (total)                      :: 7,726
            Genes (coding)                    :: 7,467
            CDSs (with protein)               :: 7,467
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 260
            CDSs (without protein)            :: 259
            Pseudo Genes (ambiguous residues) :: 0 of 260
            Pseudo Genes (frameshifted)       :: 109 of 260
            Pseudo Genes (incomplete)         :: 200 of 260
            Pseudo Genes (internal stop)      :: 18 of 260
            Pseudo Genes (multiple problems)  :: 60 of 260
            CRISPR Arrays                     :: 11
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:43:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5264139
            Orig. end                         :: 5285213
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011664.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Paul Straight
            (paul_straight@tamu.edu).
            Annotation modified by the submitter.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="15"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11074](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11074
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(112..127)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            870..1262
                     /locus_tag="M444_RS23040"
                     /old_locus_tag="M444_23025"
     CDS             870..1262
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266461.1"
                     /locus_tag="M444_RS23040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23025"
                     /product="hypothetical protein"
                     /protein_id="WP_106433349.1"
                     /transl_table=11
                     /translation="MPGRLTAAAALTALEGLALAGLGVYMLFVGIAGDPDSPQQAETGG
                     VTLLALAALPLIAARGLRLGRRWSRGPALITQLMALPVAWTLWTTGGAMAAAAVGLALA
                     AVAVVALLVNPTATEALGIGPGERTR"
     gene            complement(1272..2261)
                     /locus_tag="M444_RS23045"
                     /old_locus_tag="M444_23030"
     CDS             complement(1272..2261)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266462.1"
                     /locus_tag="M444_RS23045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23030"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_078489127.1"
                     /transl_table=11
                     /translation="MPVRGGDLPRVRHEVDGGIPEQQHARPHPADADAEYGFLDSAERR
                     AGPMSDNQHDQPESPEAAATAPVTPAPPVAAADPRDRSGARALFFELRELPEGSVERAE
                     LRNRLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATP
                     TVVGEIKRHFRDKGWAVRVPRRLQELRLSLTTATAELSQQHGRSPTVHELAERLGISEE
                     EVLEGLESANAYSTLSLDVPDTDDESPAVADTLGSEDEALEGVEYRESLKPLLEGLPPR
                     EKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(2273..2686)
                     /locus_tag="M444_RS23050"
                     /old_locus_tag="M444_23035"
     CDS             complement(2273..2686)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="M444_RS23050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23035"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_008741530.1"
                     /transl_table=11
                     /translation="MSQIAGEPGTQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVEATVEENRTVSISLYKQRGAGPGPA"
     gene            complement(2900..3160)
                     /locus_tag="M444_RS23055"
                     /old_locus_tag="M444_23040"
     CDS             complement(2900..3160)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="M444_RS23055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23040"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_008741531.1"
                     /transl_table=11
                     /translation="MSECTHVPELPRPEPVPRGQTCPDCLALGSHPVQLRLCLWCGYVG
                     CCDSSPHRHATAHYQETGHPVIRSFEPGETWRWCYVDGSIV"
     gene            3225..4805
                     /locus_tag="M444_RS23060"
                     /old_locus_tag="M444_23045"
     CDS             3225..4805
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521043.1"
                     /locus_tag="M444_RS23060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23045"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_008741532.1"
                     /transl_table=11
                     /translation="MEVLPLVALVAGSAVVAAVARRTPVPAPLLLVAAGLIAGYVPGVP
                     PYALDPHIVLPLLLPPLLYTAGVDSSYLDLRANIRPVALLSVGYVIFATVVVGYAAFLL
                     VPGLSLPVALVLGAVIAPPDAVAATAIARKLGLPNRITTILQGESLVNDATAITAYNVA
                     LAAVIGTSAGWAGGIAEFLLASVGGVGVGLLLMVPIHHLRKRLREPLLQNTLSLLIPFV
                     AYAAAERVHASGVLAVVVVALYLGHRNWQVDFATRLQEAAVWKMVAFILESVVFALIGL
                     QLPVVMKGLGEYQGVDAAWYAVVVFLVVVVARYVWVFPATFLPRLLSERVRRREPEVNW
                     KAPVVVGWAGMRGVVSLAIAFSVPISVPHRNLILFLTFTTVIATLVVQGLTLPPLIRVL
                     RLPKRDVQAETLAEAQAQSEASRAAEERLEELLADPGNGLPPPLVERLRTVLERRRNAV
                     WERLGEVNAVTGESADDVYRRLAGEMIEVEREVFVALRDRRQIDDEMLRALLRRLDLEE
                     AAAYREESP"
     gene            complement(4844..5731)
                     /locus_tag="M444_RS23065"
                     /old_locus_tag="M444_23050"
     CDS             complement(4844..5731)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491238.1"
                     /locus_tag="M444_RS23065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23050"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_008741533.1"
                     /sec_met_domain="PALP (E-value: 2.9e-18, bitscore: 65.0,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPLQPRPPSPLVEVTDERFAARGVRLLLKRDDLVHPELPGNKWR
                     KLAPNLRAAVEGGFPALVTFGGAYSNHLRATAAAGRLLGLPTIGVVRGDELAGRPLNES
                     LARCAADGMRLRFVSRAEYRRKAEPEVLARLLAGAGAAGAYVVPEGGSNALALRGCAEL
                     GRELRGAADVVAVACGTGGTLAGLAAGLGPGGRALGVPVLAGGFLGAEIRSLQLAAFGA
                     PAGDWSLAEGFHHGGYARVPAELEAFAADFEARHGLPVERIYVAKLLWALTELTRSGAV
                     PPGTTLAAVVTGRP"
     gene            complement(5769..6359)
                     /locus_tag="M444_RS23070"
                     /old_locus_tag="M444_23055"
     CDS             complement(5769..6359)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154135.1"
                     /locus_tag="M444_RS23070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23055"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_008741534.1"
                     /transl_table=11
                     /translation="MASPMSADRFISALRHEGLTVVEVGAWRTHNRNHKGPWGPVHGVM
                     VHHTVTHGTGYTVRLCREGDEDLPGPLCHGVITKDGRVHLVGYGRANHAGAGDSDVLAA
                     VIAEKRLPVDHRADTDGNRHFYGFECENLGNGEDPWPAVQLDAIARATAALCRVHGWTA
                     RSVIGHREWQPGKIDPRGFTMDAMRVRVAERLK"
     gene            complement(6530..7726)
                     /locus_tag="M444_RS23075"
                     /old_locus_tag="M444_23060"
     CDS             complement(6530..7726)
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127491.1"
                     /locus_tag="M444_RS23075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23060"
                     /product="globin domain-containing protein"
                     /protein_id="WP_008741535.1"
                     /transl_table=11
                     /translation="MLSEKSTETVRATLPAVGAAIGDIAELFYAKLFTAHPALLRDLFN
                     RGNQNSGAQKQALAGSIAAFATHLLAHPGTRPDVMLNRIAHKHASLGITREQYEVVHHH
                     LFEAIAEILGEAVTPEVAEAWDEVYWLMAGALVAIEDRLYAERRVLAGDVWRDWRIAAR
                     FEETADCATFHLVPADGAPAPAFAPGQYVSVQVELPDGARQIRQYSLSRSPGSAVRAIT
                     VKRVHGPAAAGPDGEVSHHLHTRVRTGDTLRVSAPYGDLVLRDSGAPVLLASAGIGCTP
                     MLSMLEHLADTGHTAPVTVLHADRSPADHALRGDHRSLTHKLPDASARFWYEADAEPGD
                     SHGRLDLTDVPVAPGTTAYLCGPLPFMRAVRTQLLAKGVRAADIHYEVFGPDLWLAAG"
     gene            complement(7860..8315)
                     /locus_tag="M444_RS23080"
                     /old_locus_tag="M444_23065"
     CDS             complement(7860..8315)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611275.1"
                     /locus_tag="M444_RS23080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23065"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_037793285.1"
                     /transl_table=11
                     /translation="MRLTRFTDLALRVLMRLAVADADLPTTRDVAATMEVPYTHSAKVV
                     ARLRHLGLIEARRGRGGGLALTAAGRAASVGGVVRELEGAGDVVDCDGAVPCPLRGACV
                     LRGALRGAQEAFFAALDPLTVNDLVAAPTGPLLLGISSGPPGRTVDP"
     misc_feature    complement(8335..8351)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.4"
                     /tool="antismash"
     misc_feature    8335..8351
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            8540..9949
                     /locus_tag="M444_RS23085"
                     /old_locus_tag="M444_23070"
     CDS             8540..9949
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266470.1"
                     /locus_tag="M444_RS23085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23070"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_008741538.1"
                     /transl_table=11
                     /translation="MSVQAGSETEAQSPPQRSLATSAARNLATTTKSAPQMQEITSRWL
                     LKMLPWVSVQGGTYRVNRRLSYSVGDGRVEFIKTGTQVQVIPGELGELPLLRAYEDLDV
                     LTELAARCQQLDFAAGQELTSFGSPSDKVFLLAHGRIDQVGPGPYGEDAVLQTVADGAY
                     FGEDSLVDEEAIWEYTARAATSGTALVLSRQDFQLLADRVDSLRAHVESVRSLPAQRTN
                     KYGEAAIDLSAGHQGEAVLPGTFVDYEAKPREYELSIAQTVLRVHTRVADLYNQPMNQT
                     EQQLRLTVEALRERQEHEMLNNTDFGLLHNADYDQRIQPHDGVPSPDDMDQLLSMRRGS
                     KMFLAHPKAIAAFGRECNRRGLYPESIDVGGHRVPSWRGVPIFPSSKIPISDARTTSIL
                     CMRTGEEESGVVGLHQPGIPDEIEPSMSVRFMGISEQAIISYLVTAYFSAAVLVPDALG
                     VLENVEIGRWR"
     gene            10001..11074
                     /locus_tag="M444_RS23090"
                     /old_locus_tag="M444_23075"
     CDS             10001..11074
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017236251.1"
                     /locus_tag="M444_RS23090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23075"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_008741539.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.5e-58, bitscore:
                     194.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTETITAGEGHEAAALLERTRDAVNPELRRTVESLPGSMRRVA
                     MYHFGWEHADGTPAAGNAGKAIRPALVLAAARALRGPADTGDGDGDDGLRAVVRAAVAV
                     ELAHNFTLLHDDVIDKDVRRRGRATAWTVFGTPDAIITGDAMLALALRLLAQDGHPASA
                     AASARLATCIIELCAGQQADCAFEQRPDVSLDECLTMAMAKTGALLGCACALGALYAGA
                     GPDEVDAMDAFGREAGLAFQLIDDLIGIWGDPGHTGKPAGADLIARKKSLPVVAALTSG
                     TTAGKELAALYAGPMTGDDVHAAAAAVERAGGRDWAQAHAADRMGRAVQQLSRAVPDLA
                     AAGGLLALAEFVTRRTR"
     gene            11212..11814
                     /locus_tag="M444_RS23095"
                     /old_locus_tag="M444_23080"
     CDS             11212..11814
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379088.1"
                     /locus_tag="M444_RS23095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23080"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_008741540.1"
                     /transl_table=11
                     /translation="MVLEIRQADQSDRDAVARLLDVAFRDDPVSGWVFPDPEHRAAVHG
                     KFLGVFVDVALEEGRIDCAVDGSAAALWLRVPAGDPDAEAAEDEVPARMRAAADPDNER
                     CELVGRLTGAVHPTAEEHEYLLMIAVAPGRQGEGLGTELMRPVLERCDREGLPAYLEAS
                     SERSKVLYERLGWEVTGEPVRLPDGPLMWPMWRKPRG"
     gene            11919..12500
                     /locus_tag="M444_RS23100"
                     /old_locus_tag="M444_23085"
     CDS             11919..12500
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669372.1"
                     /locus_tag="M444_RS23100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23085"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_008741541.1"
                     /transl_table=11
                     /translation="MRKLTYYVGTSVDGFIADPEGDGDFLTRWTDPEYIAHMAAEFPET
                     LPTHVQALMGLDAGAAKRFDTVLMGRGTYDPALKAGITSPYAHLEQYVLSRSLTESPDP
                     AVKIFSGDAVALVRELKARPGLGIYLCGGADLAGRLADEIDEFIVKTYPVFAGSGIPMS
                     RAGFAPRGLELTGVKTFGGGQLVTTYARAL"
     gene            12538..12747
                     /locus_tag="M444_RS23105"
                     /old_locus_tag="M444_23090"
     CDS             12538..12747
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266474.1"
                     /locus_tag="M444_RS23105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23090"
                     /product="hypothetical protein"
                     /protein_id="WP_008741542.1"
                     /transl_table=11
                     /translation="MTGQQRGEEQARIRVAPQAGHAQRVCPACGGSVDTVVRRRKSLGI
                     FVPEWVAGSCRNPDCPASVAPAAG"
     gene            complement(12744..13412)
                     /gene="snpA"
                     /locus_tag="M444_RS23110"
                     /old_locus_tag="M444_23095"
     CDS             complement(12744..13412)
                     /EC_number="3.4.24.77"
                     /codon_start=1
                     /gene="snpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266475.1"
                     /locus_tag="M444_RS23110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23095"
                     /product="snapalysin"
                     /protein_id="WP_008741543.1"
                     /transl_table=11
                     /translation="MRHSRTSRTAVLAATLGLGLATAVVGVAPTASAAPAPVGNAASYA
                     AYERSQENESANAAFFDAVRRSVAEQRAANPGIRAVTVTYNTRNAPSFRSQIARSTQIW
                     NSSVSNVKLQEVSSGGNFSYYEGNDSRGSYASTDGHGRGYIFLDYQQNQQYNSTRVTAH
                     ETGHVLGLPDHYSGPCSELMSGGGPGTSCQNPNPNAAERSRVNQLWANGLVGSGLGSKG
                     "
     gene            13620..14552
                     /locus_tag="M444_RS23115"
                     /old_locus_tag="M444_23100"
     CDS             13620..14552
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889347.1"
                     /locus_tag="M444_RS23115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23100"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_037793289.1"
                     /transl_table=11
                     /translation="MELEVRHLRALCAIADAGSLHKAARQLGVSQPSLTTQLRRIERAL
                     DGELFLRERTGCRPTPFGRTVLGRARPLLAEMAALVAEARAVARGPRLRLGSTASRALP
                     GWLRRLHRRLPDTETTLVVDLSANALLRMVDSGQLDVAFVHEVEGSPLRVPAGLEMRVL
                     MEREPQFVSMSRDHPAAARAVVDLRDLARDRWTVDPSVDGEWDGLRRVFAGAGLDPPVL
                     HADYHTATSLIISGEAVAPCQPTSGPRDDMAIRPLSGDPLAVRLLLATRPGAHAEVFED
                     LRSAYREAALRTPPYRAWLHHHESPLLAA"
     misc_feature    complement(14970..14985)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.88"
                     /tool="antismash"
     gene            14984..15919
                     /locus_tag="M444_RS23120"
                     /old_locus_tag="M444_23105"
     CDS             14984..15919
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136628.1"
                     /locus_tag="M444_RS23120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23105"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_008741545.1"
                     /transl_table=11
                     /translation="MTEQTPTRSVAEPQKLTFDEPVAELHVRLVGGTVNVVASDEGPAR
                     LEVAAVDGPPLQVVQDGGVLTVSYEDLPWNGTRGFKEWLAAKPWKAWSAGSGDGSGRKA
                     WERSATVTLTVPAATRVQVATVSAAAFVSGIRGGTDVNGVSGDATLVGLSGRVKAHTVS
                     GSVEAQSVTGELGFHSVSGGLTVVDGAGGSVRADSVSGDMLIDLALDPAAPSPVDIFLN
                     SVSGQVAIRLPHPADARVEANTATGGVSNAFEDLRVSGQLGAKRITGTLGAGTGTLRAT
                     TVSGAIALLRRPAADAATPSAPLTLDKKVL"
     gene            15921..16844
                     /locus_tag="M444_RS23125"
                     /old_locus_tag="M444_23110"
     CDS             15921..16844
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266478.1"
                     /locus_tag="M444_RS23125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23110"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_037798118.1"
                     /transl_table=11
                     /translation="MPPVFAHGRLRLYLLGLLDGAPRHGYEVIRLLEERFQGLYAPSAG
                     TVYPRLAKLEAEGLVTYATEGGRKVYSITEAGRAELADRRGELADLELEIRDSVSELAA
                     EIRADVRGAAGDLRREMRAAASATATPVEDASWAAAKEELRKAKHEWKEQARRAKDESR
                     RAREEAQQARRQAKEAQERAREEVQRIAAQFQEQFAKSGGMLGSLAGAWLGGGSAGAGS
                     GGSATGAGGAANATSATASAAAGSDWAEDLAPTADPARDLDRLLDRFRDDVRDAARDHG
                     VSPAQLAEARAHLAAAAARVTGTLRG"
     gene            complement(16841..17404)
                     /locus_tag="M444_RS23130"
                     /old_locus_tag="M444_23115"
     CDS             complement(16841..17404)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266479.1"
                     /locus_tag="M444_RS23130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23115"
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_047960683.1"
                     /transl_table=11
                     /translation="MFERFTTAARDAVTGAVAEARRAGAATVTEEHLLLALLAQGALDP
                     LGVDRAAVAAGLARARRRGGMSRADEEALAGLGIDLTRILSRVEETHGEGALAAAAPRR
                     RTLGTSLRSALGRPEPAGRHVPFAPGSKRVLEGSLRIAVGRGDRHIAAPHLLLALLSRP
                     GAVCEVLADHGVTYEAAASGLTGP"
     gene            complement(17404..17613)
                     /locus_tag="M444_RS23135"
                     /old_locus_tag="M444_23120"
     CDS             complement(17404..17613)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005312042.1"
                     /locus_tag="M444_RS23135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23120"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_008741547.1"
                     /transl_table=11
                     /translation="MTEATDLAERAGDRDPRVGLRAVAALRRLLEQLEAVQVRSARAQG
                     WSWQEIAAELGVSRQAVHKKHGRV"
     gene            complement(17698..18660)
                     /locus_tag="M444_RS23140"
                     /old_locus_tag="M444_23125"
     CDS             complement(17698..18660)
                     /NRPS_PKS="Domain: PKS_ER (15-318). E-value: 5.4e-35.
                     Score: 112.9. Matches aSDomain:
                     nrpspksdomains_M444_RS23140_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966331.1"
                     /locus_tag="M444_RS23140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23125"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_008741548.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.3e-20, bitscore:
                     70.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFAAYAARIDRDQPLSGLELGERPAPEARPGWVTVNVKAASLNHH
                     DLWSLRGVGLGEDKLPMILGCDAAGIDQDGNEVVLHSVIGQSGHGVGPDEPRSILTERY
                     QGTFAEQVTVPAWNVLPKPAELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAG
                     GGVATAAIALGKAAGLRVFATSRDEAKRKRAVELGALEAYEPGARLPRRVDAVIETVGA
                     ATWSHSVKSLRPGGTLVISGATSGDRPAHAELTRIFFLELKVVGSTMGSKDELEDLLSF
                     CAATGVRPVIDEVLPLDRAREGFEKLASGDLFGKVVLTV"
     aSDomain        complement(17707..18615)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M444_RS23140_PKS_ER.1"
                     /evalue="5.40E-35"
                     /label="M444_RS23140_PKS_ER.1"
                     /locus_tag="M444_RS23140"
                     /protein_end="318"
                     /protein_start="15"
                     /score="112.9"
                     /tool="antismash"
                     /translation="SGLELGERPAPEARPGWVTVNVKAASLNHHDLWSLRGVGLGEDKL
                     PMILGCDAAGIDQDGNEVVLHSVIGQSGHGVGPDEPRSILTERYQGTFAEQVTVPAWNV
                     LPKPAELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAGGGVATAAIALGKAAG
                     LRVFATSRDEAKRKRAVELGALEAYEPGARLPRRVDAVIETVGAATWSHSVKSLRPGGT
                     LVISGATSGDRPAHAELTRIFFLELKVVGSTMGSKDELEDLLSFCAATGVRPVIDEVLP
                     LDRAREGFEKLASGDLFGKVVL"
     CDS_motif       complement(18142..18201)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M444_RS23140_0002"
                     /evalue="2.80E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="M444_RS23140"
                     /protein_end="173"
                     /protein_start="153"
                     /score="16.7"
                     /tool="antismash"
                     /translation="GDSVLVQGAGGGVATAAIAL"
     CDS_motif       complement(18232..18270)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M444_RS23140_0001"
                     /evalue="5.60E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="M444_RS23140"
                     /protein_end="143"
                     /protein_start="130"
                     /score="13.4"
                     /tool="antismash"
                     /translation="AACLPTAWLTAYR"
     gene            complement(19101..20291)
                     /locus_tag="M444_RS23145"
                     /old_locus_tag="M444_23130"
     CDS             complement(19101..20291)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266483.1"
                     /locus_tag="M444_RS23145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_23130"
                     /product="NADP-dependent malic enzyme"
                     /protein_id="WP_086025402.1"
                     /transl_table=11
                     /translation="MVNPRSDSGTDNNPDAVFALHRGGKMAVQATVPVNDKDDLSLAYT
                     PGVAKVCTAIAENPELVHEYTWKSNVVAVVTDGTAVLGLGDIGPEASLPVMEGKAILFK
                     QFGGVDAVPIALATKDTEEIIETVIRLAPSFGGVNLEDISAPRCFEIERRLQEALDIPI
                     FHDDQHGTAIVTLAAMRNAAKLTGRTLGDLRAVISGAGAAGIAIAKILVDAGIGDVCVT
                     DRKGVVSADRSDLTDVKAEIAGLTNKSGLNGSLESALAGADVFIGVSGGTVPEEAVASM
                     AKDAFVFAMANPNPEVHPEVAHKYAAVVATGRSDFPNQINNVLAFPGIFAGALKVRATR
                     ITEGMKIAAADAIAGVVGDELAADYVIPSPFDERVATAVSAAVAAAAKADGVARLA"
     misc_feature    complement(20318..20332)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.57"
                     /tool="antismash"
ORIGIN
        1 gcgtcgggag aggcgtacag cggacgattg cccaggtatg tccacggcga ggtgttgcag
       61 actatggaca gcaccagatc cggcaccgga tcctcgccgg gccgctccag cgtgaccgtg
      121 ccgtgccgcc ggttcggctc ctccaggaac tggcgcacga gctgtcgtac atagagggcg
      181 tgcgtcgaac gcttgccgcg ctcccgctgc tgctcgaccc gccccaccac acccgcgtcg
      241 aagccgaagc ccgcgcagaa ggtgaaccag cgctccggaa ccgactcgtc cgccgtgccc
      301 ggggtgccgc ccgccaggcc caggcccacc gtccgctcgc gccgctcccg cagcgcgtcc
      361 agcagggcgc cggtcgcctc gaccgcgtcg ttgggcagtc cgagcgcgcg ggcgaacaca
      421 ttggtggagc cgccggggac caccgccagc ctcggcagcc gctccgggtc gggcccgtcg
      481 tgcagcagcc cgttcaccac ctcgttgacg gtgccgtcgc cgccgagcgc gaccaccagg
      541 tccatgccct ccagggccgc cttgcggccg aggtcccggg cgtggccgcg gtactcggtg
      601 gtgaccgcct ccagcttcat ctcgctggcc agggcgtggg tcaggacgtc acgcgtgcgc
      661 gcactggtgg tggtcgctgc tgggttggcc acgagaagtg cacgcatgag cgccagccta
      721 cccacccgtc cacgggcgac ccatactggc cgtcccctcc cgggccggcg gggcgcggct
      781 accctgctgg ggtgagtaag aagcctgcct cgaatgcccc cgcgaccgaa gcgaccggtg
      841 cgaccggtac gggcgccgct gccgccgcgc tgcccggccg gctgaccgcc gccgccgcgc
      901 tcaccgcgct ggagggcctg gcgctggccg gcctcggcgt ctacatgctg ttcgtgggca
      961 tcgccggcga ccccgactcc ccgcagcagg ccgagaccgg gggcgtgacc ctgctcgcgc
     1021 tcgccgcgct gccgctgatc gcggcccgcg ggctgcgcct gggccgccgc tggagccgcg
     1081 gcccggcgct gatcacccag ctgatggcgc tcccggtggc gtggaccctg tggaccacgg
     1141 gcggggcgat ggccgccgcc gccgtgggtc tggcgctggc ggccgtggcc gtcgtggccc
     1201 tgctggtgaa cccgacggcg acggaggctc tgggaatcgg gcccggcgag cggacccgat
     1261 agcccctgcg gctactcctc gacgaggagc ttctcccgga gctgggccag ggtccgggcc
     1321 agcaggcggg agacgtgcat ctgcgagatg ccgacttcct gcgcgatctg cgactgggtc
     1381 atgttcccga agaaccgcag cagcaggatc cgcttctccc gaggtggcag cccctccagc
     1441 agcggcttga gggactcccg gtactcgacg ccctccagcg cctcgtcctc cgagcccagc
     1501 gtgtccgcga ccgccgggga ctcgtcgtcc gtgtccggga cgtccaggga cagggtgctg
     1561 taggcattgg ccgattccag cccctccagc acctcctcct cggagatccc gagccgctcc
     1621 gccagctcgt gcacggtcgg cgagcggccg tgctgctggg acagttccgc cgtggccgtc
     1681 gtcagcgaga gccgcagctc ctgcaggcgc cggggcacgc gcaccgccca gcccttgtcg
     1741 cggaagtgcc gtttgatctc tcccaccacc gtgggggtgg cgtacgtgga gaactcgacg
     1801 ccgcggtcgg ggtcgaaccg gtccaccgac ttgatcaggc cgatcgtcgc gacctgtgtc
     1861 aggtcgtcca gcggctcgcc gcggttgcgg aaccgccgcg ccaggtgctc gaccagcggc
     1921 aggtgcatcc ggacgagccg gttgcgcagt tccgcgcgct ccaccgagcc ctcgggcagc
     1981 tcccgcagct cgaagaacag ggcccgcgcg ccactgcggt cgcgcggatc cgccgccgcc
     2041 acgggcggcg ccggtgtcac cggggccgtg gcagcggcct ccggtgactc tggctggtcg
     2101 tgctggttgt cgctcatagg gcccgcccgt cgctccgccg agtccaaaaa gccgtattcc
     2161 gcatccgcgt cagccgggtg cggccgggcg tgctgctgct ccgggatgcc gccgtcgacc
     2221 tcgtgccgta cccggggcag atccccgccc cgcaccggga tctccccgcc gctcacgccg
     2281 ggcctggtcc cgcgccgcgc tgtttgtaga ggctgatgct cactgtccgg ttctcctcga
     2341 cggtggcctc gaccttgccg gccagggccg aaaggaccgt ccacgcgaac gtgtcgcgtt
     2401 ccggtgcgcg gccgtcggtg gtaggtgccg agacggtcac ctccagcgaa tcgtccacca
     2461 gccggaagac gcagctgagg acggagcccg gcacggcctg ctggagcagg atcgcgcagg
     2521 cctcgtccac cgcgatgcgg aggtcctcga tctcgtcgag agtgaagtcc aaacgtgccg
     2581 cgagtccggc cgtggccgtt cgcagcacag acaggtaggc acccgcagcc ggcagccgga
     2641 cttccacgaa gtcctgggtc ccgggctcgc ctgcgatctg ggacaccctc acctccaagg
     2701 tggtacgagc tctgttcgcc ggtgacgcta ccgcgatccg gtcgatcgtg tcgcggcacc
     2761 cctcatggca cccgaaagga gcgcccagga cggccatgcc tctgtcagtg actgatggta
     2821 agcccatggg cacgcacagt ggctaggggt ctgcggggcc caaatcaggg gaaccggcgg
     2881 agggttgaac taccccgcct cagacgatcg aaccgtcgac atagcaccac cgccacgtct
     2941 cgcccggttc gaagctccgg atcaccggat ggcccgtctc ctggtagtgc gccgtggcgt
     3001 gccggtgggg ggaggagtcg cagcacccca cgtacccgca ccacagacag agcctcagtt
     3061 gcaccgggtg gcttccgagc gccagacaat ccggacaggt ctgcccacgt gggacaggct
     3121 cggggcgcgg cagttcggga acatgggtgc actcgctcat gatggccagc gtactgaggt
     3181 acgggcgtgc tcagtcggat gaaatcgagc gagggtgatc ttcgatggag gtattgccac
     3241 tggtggcgct ggtcgccggc agtgccgtcg tggcggcagt ggcccgccgg acgccggtgc
     3301 cggcaccgct gctgctggtc gccgccgggc tgatcgccgg gtacgtcccc ggcgtgccgc
     3361 cgtacgccct ggacccgcac atcgtgctgc cgctgctgct cccgccgctg ctgtacacgg
     3421 ccggcgtgga cagttcgtac ctggacctgc gggcgaacat ccggcccgtc gcgctgctgt
     3481 cggtcgggta cgtgatcttc gcgacggtgg tcgtcgggta cgcggcgttc ctgctcgtgc
     3541 cggggctgtc gctgccggtg gcgctggtgc tgggggcggt gatcgcgccg ccggacgcgg
     3601 tggcggcgac cgcgatcgcc cgcaagctcg ggctgccgaa ccggatcacg accatcctcc
     3661 agggtgagtc gctggtcaac gacgcgaccg cgatcaccgc gtacaacgtg gcgctggcgg
     3721 cggtgatcgg gacgagcgcc ggctgggcgg gcggcatcgc ggagttcctg ctggcctcgg
     3781 tgggcggcgt cggcgtcggc ctgctgctga tggtgccgat ccaccacctg cgcaagcggc
     3841 tgcgcgagcc gctgctgcag aacacgctgt cgctgctgat cccgttcgtg gcgtacgcgg
     3901 cggccgagcg ggtgcacgcc tccggggtgc tggcggtggt cgtggtcgcg ctgtacctgg
     3961 ggcaccggaa ctggcaggtc gacttcgcga cgcggctcca ggaggcggcg gtctggaaga
     4021 tggtcgcctt catcctggag tcggtcgtct tcgcgctgat cggactccag ctgccggtgg
     4081 tgatgaaggg gctgggcgag taccaggggg tggacgcggc ctggtacgcg gtcgtggtgt
     4141 tcctcgtcgt ggtggtggcc cggtacgtgt gggtgttccc ggcgacgttc ctgccgcggt
     4201 tgctgtcgga gcgggtccgg cggcgcgaac ccgaggtgaa ctggaaggcg ccggtcgtgg
     4261 tgggctgggc ggggatgcgg ggcgtggtct cgctggcgat cgcgttctcc gtgccgatca
     4321 gcgtgccgca ccggaacctg atcctcttcc tgacgttcac gacggtcatc gcgacgctgg
     4381 tggtgcaggg gctgacgctg ccgccgctga tccgggtgct gaggctgccg aaacgggacg
     4441 tgcaggcgga gaccctcgcg gaggcgcagg cgcagagcga ggcctcgcgg gcggcggagg
     4501 agcgcctgga ggaactcctc gcggaccccg gcaacggcct gccgccaccg ctggtggaac
     4561 ggctgcggac ggtgctggag cgccggcgca acgcggtgtg ggaacggctc ggcgaggtca
     4621 acgcggtgac gggggagtcg gcggacgacg tgtaccggcg gctcgcgggc gagatgatcg
     4681 aggtcgaacg ggaggtgttc gtggccctcc gggaccgccg ccagatcgac gacgagatgc
     4741 tccgcgccct cctgcgccgc ctggacctgg aggaggcggc ggcctaccgc gaagagtccc
     4801 cgtagcccct gtgggccggg gccgggggcc ggacgcccgg gggctacggg cgtcccgtga
     4861 cgacggcggc gagggtggtg cccgggggga cggcgccgga gcgggtgagc tccgtcaggg
     4921 cccagagcag tttcgccacg tagatccgct cgaccgggag gccgtgccgg gcctcgaagt
     4981 cggcggcgaa cgcctccagc tccgccggga cgcgggcgta gccgccgtgg tggaagccct
     5041 ccgcgaggct ccagtcgccc gccggggcgc cgaacgcggc cagctggagg gaacgtatct
     5101 ccgcccccag gaagccgccc gcaaggaccg gcacgcccag cgcgcgcccg cccgggccga
     5161 ggcccgccgc caggcccgcg agggtgccgc ccgtgccgca ggccaccgcg accacgtccg
     5221 ccgcgccccg cagctcccgc cccagctccg cacagccccg cagggccagt gcgttgctgc
     5281 cgccctccgg caccacgtac gccccggccg cgcccgcccc ggcgagcagc cgggccagta
     5341 cctccggctc ggccttgcgg cggtactccg cccgggagac gaaccgcagc cgcatgccgt
     5401 ccgccgcgca ccgcgcgagg gactcgttca gcggccgccc ggccagctcg tccccgcgga
     5461 ccacgccgat cgtcgggagg cccagcagcc gcccggccgc cgccgtggcc cgcaggtggt
     5521 tcgagtacgc cccgccgaac gtcaccagcg ccgggaagcc gccctccacc gccgcccgca
     5581 ggttcggcgc gagcttgcgc cacttgttcc cgggcagctc cggatgtacg aggtcgtccc
     5641 gcttcagcag cagccgtacc ccgcgcgcgg cgaaccgctc gtcggtgact tcgacgagcg
     5701 gggacggcgg ccggggctgc aaggggttca cccgcccatt gtcggcggag cccggcccgg
     5761 ccgccgcgct acttcaggcg ctccgcgacg cgcacgcgca tcgcgtccat cgtgaagccc
     5821 ctggggtcga tcttgccggg ctgccattcg cggtggccga tcaccgagcg cgcggtccag
     5881 ccgtgcacgc ggcacagcgc ggccgtggcg cgggcgatcg cgtcgagctg caccgccggc
     5941 caggggtctt cgccgttgcc gaggttctcg cactcgaagc cgtagaagtg ccggttgccg
     6001 tcggtgtcgg cgcggtggtc cacggggagg cgcttctccg cgatcaccgc cgccaggacg
     6061 tcggagtcgc ccgcgcccgc gtggttggcg cggccgtagc cgaccaggtg gacgcggccg
     6121 tccttggtga tcacgccgtg gcagagcggg ccgggcaggt cctcgtcgcc ctcgcggcag
     6181 agccggacgg tgtacccggt gccgtgcgtg acggtgtggt ggaccatcac cccgtgcacg
     6241 gggccccagg ggcccttgtg gttgcggttg tgagtgcgcc aggcgccgac ctccacgacg
     6301 gtcaggcctt cgtgccgcag tgcgctgatg aaccggtccg cggacatggg tgaggccatg
     6361 accgcctcct ttgcggtgcg tggtggtgac ctttcgtggt caccccgtta cgtaccggtg
     6421 tagtggaggc gatccttccg ccgctagtga attcgtacgg cgagcgagcc gatccggaca
     6481 cccgtcccgg ccgtaccggc caccccggcc ggcccgcgcg ccgcgggggt cacccggctg
     6541 ccagccagag gtccgggccg aacacctcgt agtggatgtc cgcggcgcgg acccccttgg
     6601 ccagcagctg cgtacgtacg gcccgcatga acgggagcgg cccgcacagg tacgcggtgg
     6661 tgccgggcgc gaccgggacg tccgtcaggt cgaggcggcc gtgggagtcg cccggctcgg
     6721 cgtccgcctc gtaccagaac cgggccgagg cgtccggcag cttgtgcgtc aggctccggt
     6781 ggtcgccgcg cagcgcgtgg tcggcggggg agcggtcggc gtgcaggacg gtcacgggcg
     6841 cggtgtgccc ggtgtcggcc aggtgctcca gcatcgacag catcggggtg cagccaatcc
     6901 cggcggaggc gagcagcacc ggcgcgccgg agtcccgcag gaccaggtcg ccgtacgggg
     6961 ccgagacgcg cagggtgtcg ccggtgcgga cgcgggtgtg gaggtggtgg gagacctcgc
     7021 cgtcggggcc cgccgcggcc gggccgtgga cccgcttgac ggtgatcgcg cgcaccgcgg
     7081 agccgggcga gcgggagagg ctgtactggc ggatctgccg ggcgccgtcg gggagttcga
     7141 cctgtacgga gacgtactgg ccgggcgcga aggcgggggc gggggcgccg tcggccggga
     7201 cgaggtggaa ggtggcgcag tcggccgtct cctcgaaccg ggcggcgatc cgccagtcgc
     7261 gccagacgtc gcccgcgagc acccgccgct ccgcgtagag gcggtcctcg atggcgacga
     7321 gggcgcccgc catcagccag tagacctcgt cccaggcctc ggcgacctcg ggggtgacgg
     7381 cctcgccgag gatctccgcg atggcctcga agaggtggtg gtggacgacc tcgtactgct
     7441 cgcgggtgat gccgagcgag gcgtgcttgt gggctatccg gttcagcatc acgtcggggc
     7501 gggtgccggg gtgggccagg aggtgggtcg cgaaggcggc gatggagccg gccagggcct
     7561 gcttctgggc gccggagttc tggttgccgc ggttgaacag gtcgcgcagc agggccgggt
     7621 gggccgtgaa cagcttcgcg tagaagagct ccgcgatgtc gccgatggcc gcgccgacgg
     7681 cgggcagggt ggctcgtacg gtctcggtcg acttctccga cagcatgcgg aactcctcgg
     7741 tcgcgataat tggaatctga aatgcgtatt tttgggcgtg cgggaggtgt gtggggggat
     7801 gggggcacct gttcgaggcg tggggtccgg gcagcgggaa ccggccaccc ggcccggggt
     7861 caggggtcta cggtccgccc cggcgggccg ctcgaaatgc ccagcagcag cggcccggtc
     7921 ggggccgcca ccaggtcgtt caccgtcagg gggtccaggg cggcgaagaa cgcctcctgg
     7981 gccccgcgca gcgcgccgcg caggacgcac gcgccgcgca gcgggcaggg cacggccccg
     8041 tcgcagtcca cgacgtcgcc ggcgccctcc agttcgcgga ccaccccgcc caccgaggcg
     8101 gcccgcccgg cggcggtgag cgcgagccct ccgccgcggc cgcgccgcgc ctcgatcagc
     8161 ccgaggtgcc gcagcctggc caccaccttg gcgctgtgcg tgtacgggac ctccatggtc
     8221 gccgccacgt cgcgcgtggt ggggaggtcc gcgtccgcga cggccaggcg catcaggacg
     8281 cggagcgcca gatcggtgaa tcgggtcagc cgcatggcgt caccgtacgg aaagttgcat
     8341 ctttcttgca agttaaggct gacggttggc gtggggtggc tgaaaccggt ggggctcaag
     8401 ggacctggga cgcgggagat gaccccaaag agtgcccaga cccacacgga gtagtcccac
     8461 ccttttgtgt aatggtccca ccacgtcgtg tgctgaaggc tggcccagca gacccatgga
     8521 gtgatcgaaa gggaaacaca tgtcggtcca ggcaggttcc gaaaccgagg cccagtctcc
     8581 gccgcagcgc agtctcgcga cctcggccgc acggaacttg gcaaccacga cgaagtccgc
     8641 gccgcagatg caggagatca cctcgcggtg gctcctgaag atgctgccgt gggtgtcggt
     8701 acagggcggc acctaccggg tcaaccggcg gctgagctac tccgtcggcg acggacgcgt
     8761 ggagttcatc aagacaggga cccaggtcca ggtcatcccg ggcgagctcg gcgagctccc
     8821 gctgctgcgc gcctacgagg acctcgacgt cctcaccgag ctcgccgcgc ggtgccagca
     8881 gctcgacttc gcggccggcc aggagctgac ctccttcggc agcccctccg acaaggtgtt
     8941 cctgctcgct cacggccgca tcgaccaggt cggccccggc ccctacggcg aggacgcggt
     9001 cctgcagacc gtcgccgacg gcgcctactt cggcgaggac tccctcgtgg acgaggaggc
     9061 gatctgggag tacaccgccc gcgccgccac ctccggcacc gccctcgtcc tgtcccgcca
     9121 ggacttccag ctcctcgccg accgcgtcga cagcctgcgc gcgcacgtcg agtccgtacg
     9181 gtcgctgccc gcccagcgga ccaacaagta cggcgaggcc gcgatcgacc tctccgccgg
     9241 ccaccagggc gaggccgtcc tgcccggcac cttcgtggac tacgaggcca agccgcgcga
     9301 gtacgaactc tccatcgcgc aaacggtcct gcgggtgcac acgcgcgtcg ccgacctgta
     9361 caaccagccg atgaaccaga ccgagcagca gttgcggctc acggtcgagg cgctgcggga
     9421 gcgccaggag cacgagatgc tcaacaacac cgacttcggc ctgctccaca acgccgacta
     9481 cgaccagcgc atccagccgc acgacggcgt gcccagcccc gacgacatgg accagctgct
     9541 cagcatgcgg cgcggttcca agatgttcct cgcccacccc aaggccatcg ccgccttcgg
     9601 ccgcgagtgc aaccggcgcg gcctgtaccc cgagtcgatc gacgtcggcg gccaccgggt
     9661 gccgtcctgg cgcggcgtgc cgatcttccc gagcagcaag atcccgatca gcgacgcgcg
     9721 cacgacgtcc atcctctgca tgcgcaccgg tgaggaggag tccggggtcg tcggcctcca
     9781 ccagcccggg atcccggacg agatcgagcc gagcatgtcg gtccgcttca tggggatcag
     9841 cgagcaggcg atcatctcct acctggtcac cgcctacttc tccgccgcgg tcctcgtgcc
     9901 ggacgcgctc ggcgtcctgg agaacgtcga gatcggccgc tggcgctgag ccggccggcc
     9961 ggaacgcggg agcggacgca aaggacacac gggacacgcc atggcgacca ctgagaccat
    10021 cacggccggc gagggccacg aagccgcggc cctgctggag cggacgagag acgccgtcaa
    10081 tccggaactg cgccggacgg tcgagagcct gcccggttcg atgcggcgcg tcgcgatgta
    10141 ccacttcggc tgggagcacg cggacggcac cccggcggcg ggcaacgcgg gcaaggccat
    10201 ccggcccgcc ctcgtgctcg ccgcggcccg ggccctgcgg gggccggcgg acaccgggga
    10261 cggggacggg gacgacggcc tgcgggccgt cgtgcgggcg gcggtggccg tggagctggc
    10321 gcacaacttc acgctgctgc acgacgacgt catcgacaag gacgtccggc gtcgcggccg
    10381 ggccacggcc tggaccgtct tcgggacgcc ggacgcgatc atcacgggcg acgccatgct
    10441 cgcgctcgcg ctgcggctgc tggcccagga cgggcatccg gcctcggccg ccgcctcggc
    10501 ccggctggcg acctgcatca tcgagctgtg cgccggccag caggcggact gcgccttcga
    10561 acagcgcccg gacgtctcgc tcgacgagtg cctgacgatg gccatggcca agaccggggc
    10621 cctgctgggc tgcgcctgcg cgctcggcgc gctgtacgcg ggcgcggggc ccgacgaggt
    10681 cgacgcgatg gacgccttcg ggcgggaggc cgggctggcc ttccagctga tcgacgacct
    10741 gatcggcatc tggggggatc cggggcacac cggcaagccc gccggggccg atctgatcgc
    10801 ccgcaagaag tccctcccgg tcgtggccgc cctcacctcg ggcaccacgg cgggcaagga
    10861 gctggccgcg ctgtacgcgg gccccatgac cggggacgac gtgcacgcgg cggccgcggc
    10921 ggtcgagcgg gccggcggcc gcgactgggc gcaggcccat gccgcggacc ggatgggccg
    10981 ggcggtgcag cagctgtccc gggccgttcc cgacctcgcg gcggcgggcg ggctgctggc
    11041 gctggcggag ttcgtcacgc gccgtaccag gtgacctcgt aggacgcgtc cggcggcggc
    11101 gcgcaagccc tgttccggca ccatcaggtg ccggaacagg gctttccgtg cattcggggt
    11161 caactctagg atcgctcaag gctgttgagg cgtgagcgaa gggtgtgacc catggtgctg
    11221 gagatacgtc aggcggacca gtccgaccgg gacgcggtgg cgcggctgct ggacgtggcc
    11281 ttccgcgacg acccggtgag cggctgggtc ttcccggatc cggagcaccg ggcggcggtg
    11341 cacgggaagt tcctcggcgt cttcgtggac gtggcgctgg aggagggccg gatcgactgc
    11401 gcggtggacg gctcggcggc ggcgctgtgg ctgcgggtcc cggccggtga ccccgacgcc
    11461 gaggccgccg aggacgaggt gccggcgcgg atgcgggcgg cggccgatcc cgacaacgag
    11521 cggtgcgagc tggtggggcg cctgacgggc gcggtgcacc cgaccgccga ggagcacgag
    11581 tacctgctga tgatcgcggt cgcgcccggc cggcaggggg aggggctcgg cacggaactg
    11641 atgcgtccgg tgctggagcg ctgcgaccgc gagggcctgc cggcgtatct ggaggcgagc
    11701 agcgagcgca gcaaggtgct gtacgagcgg ctcggctggg aggtcacggg ggagccggtg
    11761 cggctgccgg acgggccgct gatgtggccg atgtggcgca agccgcgggg ctgagaccgg
    11821 gcgggccgag gggtaagggg cttgtcggag tacttcaggt gcagtacttt ccctgacgtg
    11881 ccctgatcga ggggtgcggt cgagcgaaag agatctactt gcgcaagctc acgtattacg
    11941 tcggcacgtc cgtcgacggg ttcatcgcgg acccggaggg ggacggcgac ttcctcaccc
    12001 gctggaccga cccggagtac atcgcccaca tggcggcgga gttcccggag accctgccca
    12061 cccacgttca ggccctcatg ggcctcgatg cgggcgccgc gaagcgcttc gacacggtcc
    12121 tgatggggcg cggcacctat gacccggcgc tcaaggcggg gatcaccagc ccctacgccc
    12181 acctggagca gtacgtgctg tcccggtccc tgaccgagtc gcccgacccg gccgtgaaga
    12241 tcttcagcgg ggacgccgtg gcgctggtgc gcgagctgaa ggcgcggccc ggcctcggga
    12301 tctacctgtg cggaggcgcc gacctggccg gccggctggc cgacgagatc gacgagttca
    12361 tcgtcaagac gtacccggtg ttcgcgggct ccggcatccc gatgtcgcgc gccggcttcg
    12421 cgccgcgggg gctggagctg accggggtca agaccttcgg cggcggccag ctcgtcacca
    12481 cctacgcccg cgcgctctga ccccccgcgc ggagggaaac cggcctaccg tggaggtatg
    12541 accggtcagc agcgcggcga agagcaggca cgcatcaggg tcgcaccgca ggccggacac
    12601 gcgcagcgcg tgtgcccggc ctgtggcgga tccgtcgaca ccgtcgtcag acggcgcaag
    12661 tccctgggca tcttcgtacc ggagtgggtg gcgggttcct gccggaaccc ggactgtccg
    12721 gcgtccgtcg ccccggcggc cggctagccc ttcgagccca ggccggagcc gaccaggcca
    12781 ttggcccaca gctggttcac gcgggagcgc tcggcggcgt tcgggttggg gttctggcac
    12841 gaggtgcccg gaccgccgcc cgacatcagc tcggagcacg gccccgagta gtggtccggc
    12901 agacccagca cgtggcccgt ctcgtgcgcg gtcacccggg tggagttgta ctgctggttc
    12961 tgctggtagt cgaggaagat gtagccccgg ccgtggccgt cggtgctcgc gtaggaaccg
    13021 cgcgagtcgt tgccctcgta gtacgagaag ttcccgccgg aggacacctc ctggagcttg
    13081 acgttggaca ccgagctgtt ccagatctgc gtggagcggg ctatctggct acggaagctc
    13141 ggggcgttgc gggtgttgta cgtgacggtc acggcccgga tgccggggtt cgcggcacgc
    13201 tgctcggcca ccgagcgccg gaccgcgtcg aagaacgcgg cgttggcgga ctcgttctcc
    13261 tgcgagcgct cgtacgcggc gtagctggcg gcgttgccga cgggcgccgg ggcagcgctg
    13321 gcggtggggg cgacgccgac gacggccgtg gccaggccga ggccgagggt ggcggccagt
    13381 acggccgttc gggaggtacg ggagtggcgc atgtgggggg gctcctactc atccggtgcg
    13441 gggggtgggt ggttcggtac cggattctgc gggagcggaa gggggcgggg gatgatgtca
    13501 gccaccgata gctctgggtt atcggagggt ttcggcaggc caacttccct gagaatggcg
    13561 ggattcggtg ggtcgtcagt ggctggtgcg gtccactggc cccggcctac cctctggaca
    13621 tggagcttga ggtcaggcac ctgcgcgccc tgtgcgccat cgccgacgcc ggcagcctgc
    13681 acaaggcggc gcggcaactc ggcgtgagcc agccctcgtt gacgacccag ctgcgccgga
    13741 tcgaacgggc cctggacggc gagctgttcc tgcgcgagcg gaccggctgc cggcccaccc
    13801 cgttcgggcg caccgtactc ggccgggccc gtccgctgct cgccgagatg gccgcgctgg
    13861 tggccgaggc gcgtgcggtg gcccgggggc cgaggctgcg gctgggctcc acggcgagcc
    13921 gcgccctgcc gggatggctg cgccggctgc accgcaggct tccggacacc gagaccacgc
    13981 tggtggtgga cctctcggcc aacgcgctgc tgcggatggt ggattcgggt cagctggacg
    14041 tggcgttcgt gcacgaggtc gagggcagcc cgctgcgggt gcccgccggg ctggagatgc
    14101 gggtcctgat ggagcgggag ccgcagttcg tgtcgatgtc ccgggaccat ccggcggcgg
    14161 cgcgggcggt ggtggaccta cgggacctgg cgcgcgaccg gtggacggtc gacccgtcgg
    14221 tcgacggcga gtgggacggc ctgcggcggg tcttcgcggg cgcggggctc gatccgcccg
    14281 tcctgcacgc cgactaccac accgcgacct cgctgatcat ctccggcgag gcggtcgcgc
    14341 cgtgccagcc gacgtccggg ccgcgggacg acatggcgat ccggccgctg tcgggggacc
    14401 cgctggcggt gcggctgctg ctggcgaccc ggccgggggc gcacgcggag gtcttcgagg
    14461 acctccgctc ggcctatcgc gaggccgcgc tgcggacgcc gccgtaccgg gcgtggctcc
    14521 accaccacga aagccccctc ctagccgcct aacccctccg gggcgctacc ccgaccacct
    14581 gcccggccgc gccgcctgcc cgcgccggcc cccggccgct cctgccccgg tcgcgcccgc
    14641 gcccgccctg gctgcgccgc ttggccgcgc ctgccctggc tgctggggcg cctcgtcttg
    14701 ggctgtggcc cgggccattt cagcctcgcc ggcgtttgag gcgcggggtc tggggcggag
    14761 ccccagcaga cggcccgcgg ggccgaagcc tgccctgacg tgcggcgccg tcgccggggg
    14821 ccagcccccg gacccccgcg cctcaaacgc cggcggggct gaggcgggcg gccggaggcg
    14881 ggtggcttga cttcgggggg gcgcgatata tcgtgtcttt cgggagacgc gatatgttgc
    14941 gagcgtcgag acccagtccg cgcacgtccg aggaggatcc gcaatgacag agcagacgcc
    15001 gacgcggtcg gtcgccgaac cgcagaagct caccttcgac gagcccgtcg ccgagctcca
    15061 cgtacgcctg gtcggcggga ccgtcaacgt ggtcgcctcc gacgagggcc ccgcccggct
    15121 ggaggtcgcc gcggtcgacg gaccgccgct ccaggtcgtg caggacggcg gcgtcctcac
    15181 cgtttcctac gaggacctcc cctggaacgg cacccgcggc ttcaaggagt ggctcgcggc
    15241 caagccctgg aaggcctggt ccgccggctc cggcgacggc agcggccgca aggcctggga
    15301 gcgcagcgcc accgtcaccc tcaccgtccc cgccgcgacc cgagtccagg tggccaccgt
    15361 cagcgccgcc gcgttcgtct ccggcatccg cggcggcacc gacgtcaacg gagtctccgg
    15421 tgacgccacg ctcgtcggcc tctccggcag ggtcaaggcg cacaccgtgt ccggcagcgt
    15481 cgaggcccag tccgtcaccg gcgagctcgg tttccactcc gtctccggcg gcctgaccgt
    15541 ggtcgacggc gccggcggca gcgtacgggc cgactccgtc agcggcgaca tgctcatcga
    15601 cctggccctc gacccggccg cgcccagccc ggtggacatc ttcctcaact ccgtctccgg
    15661 ccaggtcgcg atccgtctgc cgcacccggc cgacgcccgc gtcgaggcca acaccgccac
    15721 cggcggggtc tccaacgcct tcgaggacct ccgggtctcc ggccagctgg gcgccaagcg
    15781 gatcaccggc accctcggcg cggggaccgg caccctgcgg gccaccaccg tctccggggc
    15841 catcgccctg ctgcgccggc cggccgccga cgccgcgacc ccctccgccc ccctcacgct
    15901 cgacaagaag gtgctctgac atgccgcccg tcttcgccca cggacgcctc cgcctctacc
    15961 tcctggggct cctggacggg gccccgcgcc acgggtacga ggtgatccgc ctgctggagg
    16021 agcgcttcca gggcctgtac gcgccctccg cgggcaccgt gtacccccgg ctcgccaagc
    16081 tggaggccga aggcctggtc acgtacgcca ccgagggcgg gcgcaaggtg tactccatca
    16141 ccgaggcggg ccgcgccgaa ctggccgacc gccgcggcga gctcgccgac ctggagctgg
    16201 agatccgcga ttcggtctcc gaactggccg ccgagatccg cgcggacgtc aggggcgcgg
    16261 ccggcgatct gcggcgcgag atgcgggccg cggcctcggc gaccgcgacc cccgtcgagg
    16321 acgcgtcctg ggcggcggcc aaggaggagc tgcgcaaggc gaagcacgag tggaaggagc
    16381 aggcgcggcg ggcgaaggac gagagtcgcc gggcccgcga ggaggcccag caggcccgcc
    16441 gccaggccaa ggaggcgcag gagcgggccc gtgaggaggt ccagcgcatc gcggcccagt
    16501 tccaggagca gttcgcgaag tcgggcggca tgctgggcag cctggccggc gcctggctcg
    16561 gcggcggatc cgcgggcgcg ggctccggcg gcagtgccac cggtgccggc ggcgccgcca
    16621 acgccacgag cgccaccgcc tcggccgccg ccggctccga ctgggccgag gacctggccc
    16681 cgacggccga cccggcccgg gacctggacc ggctgctcga ccggttccgc gacgacgtcc
    16741 gcgacgccgc ccgcgaccac ggggtctccc cggcccagct ggccgaggcc cgtgcccatc
    16801 tggccgcggc cgccgcccgc gtcaccggca cgctcagggg ttaggggccc gtcaggcccg
    16861 acgcggccgc ctcgtaggtg accccgtggt ccgcgaggac ctcgcagacc gcgcccgggc
    16921 gggacagcag ggccaggagc aggtgcgggg cggcgatgtg gcggtccccg cggcccacgg
    16981 cgatccggag ggacccttcc agcacccgct tcgagcccgg ggcgaagggg acgtggcggc
    17041 cggccggctc cgggcggccg agggccgagc ggagcgaggt cccgagggtc cgccgccggg
    17101 gggccgcggc cgccagggcg ccctcgccgt gggtctcctc cacccgggac aggatccggg
    17161 tcaggtcgat cccgaggccg gccagcgcct cctcgtcggc cctggacatc cctccccggc
    17221 ggcgggcccg ggcgaggccg gcggcgaccg ccgcgcggtc cacgcccagc gggtccagcg
    17281 ctccctgggc gagcagcgcc agtagcaggt gttcctcggt gacggtggcc gccccggccc
    17341 gccgggcctc ggccacggcg cccgtcacgg cgtcccgggc cgcggtcgtg aagcgctcga
    17401 acatcaaacc ctcccgtgct tcttgtgcac ggcctgccgg ctcacgccca gctcggccgc
    17461 gatctcctgc caggaccacc cctgcgcgcg ggcactgcgc acctgtaccg cctccagctg
    17521 ctccagcagt ctgcggaggg cggccacggc acgcaggccc acgcgcgggt cgcggtcacc
    17581 ggcccgttcg gcgagatcag tggcttccgt catgcctgtc aatgtaggtt gacgaacggg
    17641 aggtcgtcaa ccccggttga cgtgagcggg agggtgaggg gcgcgcggcc ggtccggtca
    17701 gaccgtcagg accaccttgc cgaacaggtc gcccgacgcg agcttctcga agccctcccg
    17761 cgcccggtcc agcggcagca cctcgtcgat caccggccgc acgcccgtcg ccgcgcagaa
    17821 ggacagcagg tcctccagct cgtccttcga gcccatggtc gagccgacca ccttcagctc
    17881 caggaagaag atccgggtca gctcggcgtg cgccggccgg tccccgctgg tggcgccgga
    17941 gatgaccagc gtcccgcccg gccgcagcga cttcaccgag tgcgaccagg tggccgcgcc
    18001 gaccgtctcg atcaccgcgt ccacccgccg ggggagccgc gcgcccggct cgtacgcctc
    18061 cagcgcgccc agctccacgg cccgcttgcg cttggcctcg tcccggctgg tggcgaagac
    18121 ccgcaggccc gccgccttgc cgagggcgat cgcggccgtc gcgaccccgc cgcccgcgcc
    18181 ctggaccagt acggagtcac cggggcggac gcccgcgttg gtgaacagca tccggtacgc
    18241 cgtcagccac gccgtcggca ggcaggcggc ctcctcgaag gacagctcgg cgggcttggg
    18301 caggacgttc caggccggga cggtcacctg ctcggcgaag gtcccctggt agcgctcggt
    18361 caggatggag cgcggctcgt cggggccgac cccgtggccg ctctggccga tcacggagtg
    18421 caggacgacc tcgttgccgt cctggtcgat cccggcggcg tcgcagccga ggatcatcgg
    18481 gagtttgtcc tcgccgaggc ccaccccgcg cagcgaccac agatcgtggt ggttgagcga
    18541 ggcggccttg acgttcacgg tcacccagcc ggggcgggcc tcgggggccg ggcgctcgcc
    18601 cagctcaagg ccgctcagcg gctggtcacg gtcgattcgg gcggcgtagg cagcgaacat
    18661 gccgccagac gctaccgccc ggtaggggct gccaccaggc ccggcttccc cggcgggttc
    18721 ggatcaatgg gatccgcggg aaccgggcgg gtgcggggct gcgtccagat gggtgggcgg
    18781 gggaccggag cggaatagtg agacaccttg tcaactgcgg ctcccccatg ggttcttgcg
    18841 ccatcggagg atggaaccgg aacgtcatga accagccccg gggcggggta atattcaagc
    18901 cgcgcggcac tgctcgtcat gagcctgtca ttccggctcg acggccccac gacgaacgac
    18961 ccctcccggt tcgggggcca ggagggtgcg ttccgccgcg tcccccggac gcccgtacgg
    19021 gtgtcccggg tgccgcgtca cgcgaaaggg cccggccgga gtgatccggc cgggcccctt
    19081 cacgtggaac cgggtgacgc tcaggccagg cgggccacgc cgtcggcctt cgccgcggcg
    19141 gcgaccgcgg ccgagacggc cgtggcgacg cgctcgtcga acggcgaggg gatcacgtag
    19201 tcggcggcga gctcgtcacc cacgacgccg gcgatggcgt cggcggcggc gatcttcatg
    19261 ccctcggtga tccgggtcgc gcggaccttc agggcgcccg cgaagatgcc cgggaacgcc
    19321 agcacgttgt tgatctggtt cgggaagtcc gagcggcccg tggccacgac cgcggcgtac
    19381 ttgtgcgcga cctccgggtg gacctccggg ttcgggttgg ccatggcgaa gacgaaggcg
    19441 tccttcgcca tcgaggccac cgcctcctcg ggcaccgtgc cgccggagac gccgatgaac
    19501 acgtcggcgc ccgcgagggc ggactccagc gagccgttca ggccgctctt gttcgtcagg
    19561 cccgcgatct ccgccttgac gtccgtcagg tcggagcggt ccgcggagac gacgcccttg
    19621 cggtcggtga cgcagacgtc gccgatgccc gcgtccacca ggatcttggc gatggcgatg
    19681 cccgccgcgc ccgctcccga gatcacggcg cgcaggtcgc cgagggtgcg gccggtcagc
    19741 ttcgccgcgt tgcgcatggc ggccagcgtc acgatcgccg tgccgtgctg gtcgtcgtgg
    19801 aagatcggga tgtccagggc ttcctggagc cggcgctcga tctcgaagca gcgcggggcg
    19861 gagatgtcct ccaggttcac gccgccgaac gagggcgcga gacggatgac cgtctcgatg
    19921 atctcctcgg tgtccttggt cgcgagcgcg atcggaaccg cgtcgacccc accgaactgc
    19981 ttgaacagaa tggccttgcc ctccatcacg gggagggagg cctcgggccc gatgtcaccg
    20041 agtccgagca cggccgtacc gtcggtgacg acggccacga cgttggactt ccaggtgtac
    20101 tcgtggacga gctccgggtt ctccgcgatg gcggtgcaga ccttggccac acccggcgtg
    20161 tacgcgaggg acaggtcgtc cttgtcgttg acgggcacgg tggcctgcac ggccatcttg
    20221 ccgccccggt gcagcgcgaa caccgcatcg gggttgttgt ccgtcccgct gtcgctgcga
    20281 ggattgacga tctccgctgc cactttcttg gccccttaag tttttgaatc gttgagggtg
    20341 accactcctg gttaaggggt gggcgggcac cgcgtccgta ctccgcgccg acggcttgcc
    20401 cgtctgcgcg gaggggaggt tcgtacgcgc gggcgcgccg cacgcgcgcc ctgagcccct
    20461 ggtgaggggt gtaaggatcc gttttaccgg aagaacgctc gcccagacga gtcgattcct
    20521 gctcgaccct aagcctgctg tcccggtttt ggcgaaaggt ccaaacctta ctgtccaaca
    20581 gtcgagacgc acagtaaatg ctgcggtgaa agtcgctggt cacagcgcat agtccggccg
    20641 gaagagcctg cgcccgcagg gctgatgggc cgccggggat gtccgttatc cgattttgac
    20701 ctgacgagct gcctgaatgc gtcagtccga atggcaagat gccgtaacca cacaaggtcg
    20761 cgacactcga tggtgcgtgc cacgaccgtt ttcggatgct ttccacctgt cggaggaacc
    20821 agcccatgac cgcaagcacc acccgtcgta cgaccgccgc ccggtcccgc atcgccgcgg
    20881 tcggcgcgat cgcggtcgcc ggcgccctcg tcctcaccgg ctgtggtgac cagaccgaga
    20941 gcggcggctc gtccaccccc tcctcctcgg ccaagaagga caacgcggcc cccctcttct
    21001 cggccctgcc gaagaagatc caggacgccg gtgtcatcaa ggtcggcacg gactcggcgt
    21061 acgcgccgat ggag
//
