LOCUS       NZ_CP011664            22333 bp    DNA     linear   CON 03-MAR-2024
DEFINITION  Streptomyces sp. Mg1 chromosome 1, complete sequence.
ACCESSION   NZ_CP011664
VERSION     NZ_CP011664.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. Mg1
  ORGANISM  Streptomyces sp. Mg1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     De Novo Assembly of the Streptomyces sp. Strain Mg1 Genome Using
            PacBio Single-Molecule Sequencing
  JOURNAL   Genome Announc 1 (4), e00535-13 (2013)
   PUBMED   23908282
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUN-2015) Biochemistry and Biophysics, Texas A&M
            University, 300 Olsen Blvd., College Station, TX 77845, USA
REFERENCE   3  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JUN-2013) Biochemistry and Biophysics, Texas A&M
            University, 2128 TAMU, College Station, TX 77843, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 8.2
            Genome Coverage                   :: 30X PacBio; 80X Illumina
            Sequencing Technology             :: PacBio + Illumina MiSeq/HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 08:10:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,822
            CDSs (total)                      :: 7,726
            Genes (coding)                    :: 7,467
            CDSs (with protein)               :: 7,467
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 260
            CDSs (without protein)            :: 259
            Pseudo Genes (ambiguous residues) :: 0 of 260
            Pseudo Genes (frameshifted)       :: 109 of 260
            Pseudo Genes (incomplete)         :: 200 of 260
            Pseudo Genes (internal stop)      :: 18 of 260
            Pseudo Genes (multiple problems)  :: 60 of 260
            CRISPR Arrays                     :: 11
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:43:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2448304
            Orig. end                         :: 2470637
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011664.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Paul Straight
            (paul_straight@tamu.edu).
            Annotation modified by the submitter.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22333
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="10"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22333
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22333
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12333](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12333)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(188..496)
                     /locus_tag="M444_RS10325"
                     /old_locus_tag="M444_10305"
     CDS             complement(188..496)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M444_RS10325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M444_10305"
                     /product="hypothetical protein"
                     /protein_id="WP_037797409.1"
                     /transl_table=11
                     /translation="MPTLLRNLLLLAVEFGAAHLLRSPDPAPWIPVLLAVFVVGSGVLH
                     GTDAEFVPRFLLAFVAVGVAWLGGAAGEAADSVPAAGAVTLLVIQTALLIRFSRRGG"
     tRNA            540..610
                     /anticodon=(pos:2448876..2448878,aa:Ala,seq:agc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="M444_RS10330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="M444_10310"
                     /product="tRNA-Ala"
     gene            540..610
                     /locus_tag="M444_RS10330"
                     /old_locus_tag="M444_10310"
     gene            complement(650..1378)
                     /locus_tag="M444_RS10335"
                     /old_locus_tag="M444_10315"
     CDS             complement(650..1378)
                     /EC_number="1.1.1.47"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-166). E-value: 1.1e-12. Score:
                     40.1. Matches aSDomain:
                     nrpspksdomains_M444_RS10335_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007263546.1"
                     /locus_tag="M444_RS10335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10315"
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_078899671.1"
                     /sec_met_domain="adh_short (E-value: 1.3e-30, bitscore:
                     105.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISLDGKVVVITGAGRGQGAAEARLCAEAGARVVVTDVREDEGRA
                     VAAELGPRGLFVRHDVADAGSWAGVVREAVSAFGTISALVNNAALWRTAHVEQQTAEDF
                     EALLRVNLLGPFLGIQAVAPVLRAAGGGSIVNISSTAGLVGIPGHAAYGSTKFALRGLT
                     RSAALDLAGDGIRVNSVHPGAIDTPMVAAAVGGRDWSHVPLGRMGRPEEVGELVLFLCA
                     DASAYVTGAEFAVDGGMTAR"
     aSDomain        complement(881..1357)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M444_RS10335_PKS_KR.1"
                     /evalue="1.10E-12"
                     /label="M444_RS10335_PKS_KR.1"
                     /locus_tag="M444_RS10335"
                     /protein_end="166"
                     /protein_start="7"
                     /score="40.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGAGRGQGAAEARLCAEAGARVVVTDVREDEGRAVAAELGP
                     RGLFVRHDVADAGSWAGVVREAVSAFGTISALVNNAALWRTAHVEQQTAEDFEALLRVN
                     LLGPFLGIQAVAPVLRAAGGGSIVNISSTAGLVGIPGHAAYGSTKFALRGLTRSA"
     CDS_motif       complement(920..973)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M444_RS10335_0001"
                     /evalue="6.80E-05"
                     /label="PKSI-KR_m4"
                     /locus_tag="M444_RS10335"
                     /protein_end="153"
                     /protein_start="135"
                     /score="15.4"
                     /tool="antismash"
                     /translation="NISSTAGLVGIPGHAAYG"
     misc_feature    complement(1405..1418)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.94"
                     /tool="antismash"
     gene            1475..2065
                     /locus_tag="M444_RS10340"
                     /old_locus_tag="M444_10320"
     CDS             1475..2065
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018533159.1"
                     /locus_tag="M444_RS10340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10320"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_037797410.1"
                     /transl_table=11
                     /translation="MADETNERALPPTGWAVLGLLSFGEELSGYDLKKWSDRSLRFFYW
                     SPSFSQIYSELGRLERAGYASSRTVAQGSGTRDKRVYRITGSGMAAARRWAREAPVDPP
                     VLKHGPMLRLWLGHLLEPEQMREVLLRQQEFAEDMRLRAVADAQAAKEEPAWAYPALTL
                     RWAERYYARERDLAAAMLDDLAALENGPGEDRG"
     gene            2080..2808
                     /locus_tag="M444_RS10345"
                     /old_locus_tag="M444_10325"
     CDS             2080..2808
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007263548.1"
                     /locus_tag="M444_RS10345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10325"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_037797412.1"
                     /transl_table=11
                     /translation="MTGSAIDLRKVEETAPALVSLYKSAGVSLRKYGLEGGRAAVYLVL
                     DYSGSMRPYYEDGSVQALADQVLGLSAHLDDDGRVPVVFFSTDIDAIAEISLAGHAGRV
                     TEIAAGLGHMGKTAYHLAMDAVIDHYLDSGATDPALVVFQTDGGPVSKLAAERYLCKAA
                     RLPLFWQFVGFGNTRSSQFDFLRRLDELPVPGRRVVDNAGYFHAGPDPRTVPDGELYDR
                     LVAEFPAWLAAARGAGIVRA"
     gene            2845..3357
                     /locus_tag="M444_RS10350"
                     /old_locus_tag="M444_10330"
     CDS             2845..3357
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007263549.1"
                     /locus_tag="M444_RS10350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10330"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_037797414.1"
                     /transl_table=11
                     /translation="MTHTSWAVFEKAEPEFAAAVEARFAQYPHHVLATLRKDGSPRVAG
                     LNVDIRGGELWLGMMQGSMKARDLERDPRFALHTNPGEGETMPDGDVRISGRAVELLDP
                     PELHRYAEERDSPHPFHLFYADLTEVVHIGIDGDDLVLRTWTPAGGVHTVRRGDDDEPP
                     HEEPTTS"
     gene            complement(3350..4660)
                     /locus_tag="M444_RS43885"
                     /old_locus_tag="M444_10335"
     CDS             complement(3350..4660)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984438.1"
                     /locus_tag="M444_RS43885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10335"
                     /product="DUF1906 domain-containing protein"
                     /protein_id="WP_261340369.1"
                     /transl_table=11
                     /translation="MLGTALLAPAVPAAAGPAGPAAGPTVDYRGLRLTLPAGWRVVDLD
                     RNPGACLRLDLPSLYLGHAGTQAECTGRAVRTRADTLHLEPLDDTPPRADIPTVAADDL
                     RALPATRADSNEVRYALRRSGVMATLSYGSGPGVVRGLLAQLRTAPGPAPATPAAPAAT
                     AAAARTAAAAAAGAVLAGPRGAQEAFTGQGFDTCTAPTQRAMDAWHGASPFGAVGVYIG
                     GRARACAQPRLTANWLRRQIGAGWHLMPIWVGPQPWHNADTGLSTDPSEANEQGKEAAE
                     GAAQAARSLGLAGGTLLYNDLENYTDRATWDAPVVAYLTAWTVRLHELGYRSAAYVAAS
                     SGVKALSAHHHQAPEAMPDVIWVAVWNGRASVADADMGLPAGKKLWAGRRRAHQFRGDH
                     EATYGDVTLKIDRSWLDLEPAALARPGGPGPGPGPFS"
     gene            complement(4952..5617)
                     /locus_tag="M444_RS10360"
                     /old_locus_tag="M444_10340"
     CDS             complement(4952..5617)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M444_RS10360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="M444_10340"
                     /product="hypothetical protein"
                     /protein_id="WP_124288676.1"
                     /transl_table=11
                     /translation="MRRLPGLIVPLLTVPLLALAGCGGGGQTRTAPPSVPASPSPLSPS
                     PDPAPSPSPSSTRNRLCVPTTDMTTAERLAYFKDLSDSSHGASPAFFMTDSGVYLLAKE
                     TQRPCEAVRFQLSWFRVEMTRAGSGSSARYSFTYAPIESTTLSAGPRDGRVVGSVPPPP
                     KGCSGTLSVVYVGEEITEDDLPDGLNMPGGSLDWSLVTLDADRALSAVFKPPAGASSC"
     misc_feature    complement(5606..5608)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5746..8697
                     /locus_tag="M444_RS10365"
                     /old_locus_tag="M444_10345"
     CDS             5746..8697
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576163.1"
                     /locus_tag="M444_RS10365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10345"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_063781016.1"
                     /transl_table=11
                     /translation="MTDRTPLVGREAELDRLDAVLDGPGGPPGVVDLTGAAGIGKSRLL
                     TEVCGRAEERGLTVLRGRATEYERHIPFRVFGDAFADLDPELLRGLGAPGAAWAASAGA
                     AADGISANPAVDPTGAGAGAGAGVGAGAEAGAGAGAGAGAGAGAGAGVSAVDRFAAHRA
                     TARLLTALGGRTGAGLLIALDDLHWADPASLELLDHLVRHPLRAPVVIVVARRDRQTAP
                     SLAAALTRGVDTGAVLRLDLGPLTERACVEQLAPGLPPDRAARLYAASEGNPLYFLTLL
                     QGQEQGRSGPALPPGGLGALLLDELTPLSAAQRRTAEAVAVLGDQATPPLLLALTEPAS
                     ASGPERLDADLGVLARRDLIRPRPGGVWSLRHPVLRAAVYEDTGPGRRAALHRRAAAAL
                     AAAGAPATVRAHHVERALTDWEPEAAAVLLEAAEQSETTAPASCAHWLEVVLRVLPDTP
                     GHAARRRDLMLKRARALSVCGELRASRDLLHEVIAGLPADDGSGVRAAAVTLCASMERH
                     LGQYRASVALLRRALSRRPAPAPADAVALGLELGSSAPHALPFPAVRAEVLRTLELARA
                     LGNEPAAAGALAVSALGEAYEGNTAAARELTDRAAACVDALTDRDLADQCEPLARLGWA
                     EFYLERYEDAERHADRGLAIARRGGPLHLLPHLLMCKAIVHTHACRLPSALDLVDEAES
                     IARGIGSDELLGLVLANKAQVLIAARPPGDVSALAAAEEAVAAAGARTSWWTSLVWCVM
                     SYAALHGGDPVRARSAMLRAGGADLAGLQPSMRPLFLEALVTAAVTTGDLAGAQEWAAL
                     AGRDAERLGLPVQRAAALRCAGQVLAGSGRPAAAAERFARAAEEAGRSGAVLWEAQSLL
                     IGASLTAEAGDPATASAMWRRGRRLAESGGSLLLTGLADLLLPPPPPPRVPGLTPREHE
                     IAALVAEGLTTPAIAARLYLSPRTVDTHLSHIFRKTGVTTRSALAALTARHLP"
     misc_feature    7186..7188
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8745..>9386
                     /locus_tag="M444_RS10370"
                     /old_locus_tag="M444_10350"
                     /pseudo=""
     CDS             8745..>9386
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007264926.1"
                     /locus_tag="M444_RS10370"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10350"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNRSLPIAALVDLRRQPMEDVLERVEEALRVRLDREALVRKRRSL
                     GGRTERGTWVRIERRGFERIGPQGWNGTEAAAVLQGVAMPEWYRGVAWREPGEPVMWRA
                     DELELLASASVAGGALVLEDPGLPDAWWAALNASLDALADQQTPRIATPDTVTITQEQV
                     TRTLGEVFPGVTDTRIERWAPAHADLTWANVMAPEFSIVDWEDWGMAPRGL"
     gene            complement(9453..10004)
                     /locus_tag="M444_RS10375"
                     /old_locus_tag="M444_10355"
     CDS             complement(9453..10004)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137214.1"
                     /locus_tag="M444_RS10375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10355"
                     /product="GNAT family protein"
                     /protein_id="WP_008743980.1"
                     /transl_table=11
                     /translation="MSAPHILLPGERVSLAMTNRDHLPDYHRWENDPATILGYGTQVTQ
                     SWEVRAGGWEGQGRNRDYAQFEVITADDYAPVGLTTLQIDSAVRTAEFVILIAPESRGK
                     GLATEATSLTLRWAFEYAALRMVWLKVLEANTAGVTAYQKAGFQSAGRLRQSGYWLGRS
                     CDEILMDATADDFLSATESA"
     gene            complement(10001..10636)
                     /locus_tag="M444_RS10380"
     CDS             complement(10001..10636)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137215.1"
                     /locus_tag="M444_RS10380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_106433441.1"
                     /sec_met_domain="PF13471 (E-value: 2.8e-20, bitscore: 71.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPVPTAETRTAVTDRAGVIVNYRTGATIVLTGGALDEWLSAVRQ
                     GNAPKPVVVTNPGASWGTHETAARLESHGSPPWPWRVAALACVALTLTVRQTGRSEYRF
                     GRLVRLASVGGALPPASAVHARTAVRSVRWAARAIPARVACLEESTAASVLLAAGGRGN
                     AWRHGVAADPIRLHAWICDEHGRPVEEPGHTGDYTPINTANSSGAEPR"
     gene            complement(10633..12333)
                     /locus_tag="M444_RS10385"
                     /old_locus_tag="M444_10360"
     CDS             complement(10633..12333)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137231.1"
                     /locus_tag="M444_RS10385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10360"
                     /product="albusnodin/ikarugamycin family macrolactam
                     cyclase"
                     /protein_id="WP_050779430.1"
                     /sec_met_domain="Asn_synthase (E-value: 8.8e-37, bitscore:
                     126.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGWFGGYLRTASRPTVPVGAQILWPDPPVWSAGAPVRLVDGPHGR
                     RLVVFGPCGAMDADLDRLAQAGDLRSLDSAATAWAGAYTLLYDDGHDALTVWADPAGAC
                     PLYTCTFNGSTVWASSAHALAALCGSLPDAGWMAAHLVDPTGWTPGFSAWSNVEQVAPG
                     HRIAAGLRAEPVPVPYWTPPALTREEAVDWLREDLAEGVRIRVTGRPVSSDLSGGLDSS
                     ALAALAARCGPVTAVTYHPEGIKAGGDVDHACLVARAYPAIRHEFMALDDSHLPFSDLD
                     ALPLTDEPAPSAITIAQFTAQLRFLADHGAVVHLTGDGGDNLFMPPPVHVADLARSGHW
                     LRLAADAQTWARLYRQSPWPFLVNAVRRPRTLAGSSGPMPWMTDYAKELAAPVSAAYPD
                     TLNMGHADRALLTEARYVGRTAATENQLAAAHGIEMHNPFTDTRVVEAALAAPAVERWS
                     ARRYKPLLSDVVAGLLPPPVVRRGAKGMFAVDHHHGLRVNLQRALDLADGHLADLGLIN
                     PEMVRATLRRAVLGVDIPWGRLEPALGAELWLRAAEKVDQWITWEERAA"
     misc_feature    complement(11485..11487)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11752..11754)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12394..12525)
                     /locus_tag="M444_RS40930"
     CDS             complement(12394..12525)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033525.2"
                     /locus_tag="M444_RS40930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="albusnodin family lasso peptide"
                     /protein_id="WP_008743983.1"
                     /transl_table=11
                     /translation="MNEIIKASDPDENEEIVPLGDAAALTKGSTSESIENKRSPYSA"
     gene            13254..13976
                     /locus_tag="M444_RS10390"
                     /old_locus_tag="M444_10365"
     CDS             13254..13976
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946834.1"
                     /locus_tag="M444_RS10390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10365"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_335338031.1"
                     /transl_table=11
                     /translation="MTEKQLAEVCGVDAKTVGRWITDANRIPHARHRWAACEALGEEEK
                     IVWPNAIRSAFATGPDREIVQVFPYRSAAPASLWRSLVTKAQSDLVFAGYTNYFLWLEQ
                     ANLGGALRRKAQAGCRVRFLIGDPDSPITAAREEEEGVPLTLSTRIAVTLAELEKLRDV
                     AGIEGRFESGHVNLSVFRFDDEMIVTPILARRVGHDSPMMHLRRCQADGMFDRFAAHVE
                     ELWSRGRDIREARHHAQA"
     misc_feature    13371..13373
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13963..14430
                     /locus_tag="M444_RS10395"
                     /old_locus_tag="M444_10370"
     CDS             13963..14430
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018545063.1"
                     /locus_tag="M444_RS10395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10370"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_008743987.1"
                     /transl_table=11
                     /translation="MPRRDYEDDPNAPKANSLVPAASAVVVDDEGRILLQRRTDNGMWA
                     LPGGKMELGESLGECAARETLEETGMTVEITGIVGTYTNPGHVFAYDDGEVRQEFSICL
                     LARPTSGTLRTSDESFEVAWFTPDEVDGLPMVPSIRKRVNDWRMGAGPVVR"
     gene            complement(14874..16334)
                     /locus_tag="M444_RS10400"
                     /old_locus_tag="M444_10375"
     CDS             complement(14874..16334)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285: ferredoxin fdxC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119967.1"
                     /locus_tag="M444_RS10400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10375"
                     /product="glutamate synthase subunit beta"
                     /protein_id="WP_008743988.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.9e-30, bitscore:
                     104.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADPKGFLTTGRETACSRPVAERLGDWNEVYVPGSLLPIISKQAG
                     RCMDCGIPFCHNGCPLGNLIPEWNDFAYREDWSAAAERLHATNNFPEFTGRLCPAPCES
                     ACVLGINQPAVTIKNVEVSIIDKAWDNGGVTPQPPERLSGKTAAVIGSGPAGLAAAQQL
                     TRAGHTVVVYERADRIGGLLRYGIPEFKMEKVHINRRIEQMRAEGTKFRTGIEIGRDLS
                     ATDLRKRFDAVVVAAGATVSRDLPVPGRELGGIHFAMEYLPLANKVQEGDFMAPPITAE
                     GKHVVVIGGGDTGADCVGTAHRQGAASVTQLEIMPRPSEDRPTGQPWPTFPMLYKVTSA
                     HEEGGERIYSVSTTHFEGDEDGNVQALHLVEVAFEDGKLVQKAGTERVLPAQLVTLAMG
                     FTGTDQANGLVEQFGLELDARGNVERDASYATNVDGVFVAGDAGRGQSLIVWAIAEGRS
                     AARGVDRYLTGTSALPYPVKPTDRSLMV"
     gene            complement(16327..20880)
                     /gene="gltB"
                     /locus_tag="M444_RS10405"
                     /old_locus_tag="M444_10380"
     CDS             complement(16327..20880)
                     /EC_number="1.4.1.13"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0015930 - glutamate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="gltB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743989.1"
                     /locus_tag="M444_RS10405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10380"
                     /product="glutamate synthase large subunit"
                     /protein_id="WP_037799525.1"
                     /transl_table=11
                     /translation="MDGRPAPQGMYDPRNERDACGVGFVANLSGEAGHTLVEQALTVLR
                     NLEHRGATGSEPDSGDGAGILSQVPDAFLREVAGFELPEAGAYAVGIAFLPADGTAQAA
                     AVERIEAIAAEENLTVLGWREVPVTPDLLGNGARATMPAFSQLFVSNGSTGIELDRKAF
                     VLRKRAEREAGVYFPSLSARTIVYKGMLTTGQLEPFFPDLSDRRFASTLALVHSRFSTN
                     TFPSWPLAHPYRFVAHNGEINTVKGNRNWMKARESQLASDAFGDGALDRIFPICTPDAS
                     DSASFDEVLELLHLGGRSLPHSVLMMIPEAWENHASMDPARRAFYQYHSTMMEPWDGPA
                     CVTFTDGTQVGAVLDRNGLRPGRYWVTDDGLVVLGSEVGVLDIDPAKVVRKGRLQPGKM
                     FLVDTAQKRIIEDDEIKAELAGAAPYAEWLETGEIELTDLPEREHIVHTHASVTRRQQT
                     FGYTEEELRVILAPMARTGGEPLGSMGTDSPIAALSARPRLLFDYFTQLFAQVTNPPLD
                     AIREELVTSLLSSLGPQGNLLEPTSASCRSVTLPFPVIDNDELAKLIHVNADGDMPGMK
                     AATLAGLYRVSGGGESLAARLEEIRGEVDAAIAGGAHLIVLSDRHSDAEHAPIPSLLLT
                     SAVHHHLIATKQRTQVGLLVEAGDVREVHHVALLIGYGAAAVNPYLAMESVEDLLRAGT
                     FLSGLEPEQAIKNLIYALGKGVLKVMSKMGISTVASYRGAQVFEAVGLNEEFVASYFEG
                     TATKIGGAGLDVIAKEVAARHAKAYPASGIAATHRALEIGGEYQWRREGEPHLFDPETV
                     FRLQHATRNRRYDIFKKYTERVNEQSERLMTLRGLFGFKAAEDGGRPSIPLDEVESVAD
                     IVKRFSTGAMSYGSISREAHETLAIAMNQLGGKSNTGEGGEDPDRLYDPARRSSIKQVA
                     SGRFGVTSEYLVNADDIQIKMAQGAKPGEGGQLPGHKVYPWVAKTRHSTPGVGLISPPP
                     HHDIYSIEDLAQLIHDLKNANPVARIHVKLVSEVGVGTVAAGVSKAHADVVLISGHDGG
                     TGASPLTSLKHAGGPWELGLAETQQTLLLNGLRDRIVVQTDGQLKTGRDVVIAALLGAE
                     EFGFATAPLVVSGCVMMRVCHLDTCPVGIATQNPVLRDRFSGKAEFVVNFFEFIAEEVR
                     EILAELGFRTIEEAVGHAELLDTSKAVTHWKAQGLDLEPLFHVPQLPEGAVRHALIEQD
                     HGLEKALDNELIELASEALNADTAETAQPVRAQVAIRNINRTVGTMLGHHVTKKFGGAG
                     LPDNTIDLTFTGSAGQSFGAFLPRGVTLRLEGDANDYVGKGLSGGRVVVRPDRAADHLA
                     EYSTIAGNTIGYGATGGEMFLRGRTGERFCVRNSGALVVSEGVGDHGCEYMTGGQAVVL
                     GETGRNFAAGMSGGVAYVIDLDPHHVNVGNTDAVETELSDTDKQWLHDVVRRHEEETGS
                     TVAAKLLADWSVAADRFSKIIPTTYKAVLAAKDAAELAGLSESETTEKMMEAATHG"
     misc_feature    complement(21011..21027)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.39"
                     /tool="antismash"
     misc_feature    21029..21046
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.05"
                     /tool="antismash"
     misc_feature    complement(21121..21130)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     gene            complement(21305..22036)
                     /locus_tag="M444_RS10410"
                     /old_locus_tag="M444_10385"
     CDS             complement(21305..22036)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059948.1"
                     /locus_tag="M444_RS10410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_10385"
                     /product="VIT1/CCC1 transporter family protein"
                     /protein_id="WP_037797418.1"
                     /transl_table=11
                     /translation="MSIIDTAAPLHTAHRDNHSHRDVNGGWLRPAVFGAMDGLVSNIAL
                     MTGVAGGAAAPQTIVITGLAGLAAGAFSMAAGEYTSVASQRELVLAELDVERQQLRKHP
                     VDEMEELAELYVSRGVEPALAREVAMQLSRDPEQALEIHAREELGIDPEDLPSPLVAAV
                     SSFASFALGALLPVLPYLLGATALWPAVLLALVGLFACGAVVARVTARSWWFSGLRQLV
                     LGGAAAGVTYILGTWIGGAVG"
ORIGIN
        1 agcggccggc cggtgagctc ctcgacggcg tcgaacagcc cgccggggta cccgggccgg
       61 ctggcggcgt acagcgcggc ggcggcatcg aaggaccgcg ctcgcgcacg ggggttcgtg
      121 gtcatcggcc catccttccc gatcccgggc cggccaccat tgcctttcgg gggcgggaga
      181 ggacggccta gcctccgcgc cgggagaagc ggatcaggag ggccgtctgg atcaccagca
      241 gggtcaccgc tccggccgcg gggacggagt ccgccgcctc cccggccgcg ccgcccagcc
      301 aggccacgcc caccgccacg aaggcgagga ggaagcgcgg cacgaactcg gcgtccgtgc
      361 cgtgcagtac gccggagccg acgacgaaga cggccagcag gaccgggatc cagggcgccg
      421 ggtccgggct ccgcaggagg tgcgcggcgc cgaactccac cgccaggagc aggaggttgc
      481 ggagcagcgt gggcatgagc acatcatgcc gggcgtgccg tagggttgat cacaagggtg
      541 gggtcgtagc acagaggcag tgcgcctaca cagcatggag gaggacgccg gttcgaatcc
      601 ggccgccccg ccccccgagc ccggccgcgc cccgggcccg gccgcgccgc tagcgcgccg
      661 tcattccgcc gtcgaccgcg aactccgccc ccgtcacgta cgcggaggcg tcggcgcaca
      721 ggaacagcac cagttccccc acctcctccg gccggcccat ccgccccagc gggacgtgcg
      781 accagtcccg gcccccgacc gccgccgcga ccatcggggt gtcgatcgcg cccgggtgca
      841 ccgagttcac cctgatcccg tcccccgcca ggtccagcgc cgccgagcgg gtcaggccgc
      901 gcagggcgaa cttggtggag ccgtacgccg cgtggcccgg gatgccgacc agcccggccg
      961 tggaggagat gttgacgatc gagccgccgc cggccgcccg cagcaccggc gccaccgcct
     1021 ggatgccgag gaacggcccg agcaggttga cccgtagcag cgcctcgaag tcctcggccg
     1081 tctgctgctc cacgtgcgcc gtccgccaca gcgccgcgtt gttgaccagg gccgagatcg
     1141 tgccgaaggc cgacaccgcc tcccgcacca ccccggccca gctcccggcg tcggccacgt
     1201 cgtgccgcac gaacagaccc cgggggccga gttccgccgc gaccgcccgg ccctcgtcct
     1261 cccgtacgtc cgtgaccacg acccgcgcgc cggcctccgc gcagagccgg gcctcggccg
     1321 cgccctggcc gcgcccggct ccggtgatga cgacgacttt tccgtccagc gagatcacgg
     1381 ctcagacctc cgggtcgttt tgattcggaa tacttctagc agtcatgcgg cggggagggg
     1441 aacggccgcg ggggccggtc gtagactgcg ccgcgtggca gacgagacga acgagcgcgc
     1501 cctccccccg accggctggg cggtgctcgg actgctgtcc ttcggcgagg aactctccgg
     1561 ctacgacctg aagaagtggt cggaccggtc gctgcgcttc ttctactgga gcccctcctt
     1621 cagccagatc tacagcgagc tggggcgcct ggagcgggcc ggatacgcct cctcccggac
     1681 ggtcgcccaa ggcagtggta cccgcgacaa gcgcgtctac cggatcaccg gctccggcat
     1741 ggccgccgca cggcgctggg cccgcgaggc cccggtcgac ccgcccgtcc tcaagcacgg
     1801 gccgatgctg cggctgtggc tgggacacct gctggagccg gagcagatgc gcgaagtgct
     1861 gctccgccag caggagttcg ccgaggacat gcggctgcgt gcggtggccg acgcgcaggc
     1921 ggcgaaggag gagcccgcct gggcgtaccc ggcgctgacc ctcaggtggg ccgagcggta
     1981 ctacgcccgc gagcgcgacc tcgccgcggc catgctcgac gacctcgccg ccctggagaa
     2041 cggccccggc gaggaccggg gctgacgtac cctcgggcca tgacgggcag cgcgatagac
     2101 cttcgcaagg tggaagagac cgcaccggcg ctggtgagcc tctacaagag cgccggggtc
     2161 tccctccgca agtacggcct ggagggcggc cgggcggcgg tctacctggt cctggactac
     2221 tccggttcga tgcgcccgta ctacgaggac ggcagcgtgc aggccctcgc ggaccaggtg
     2281 ctgggcctgt cggcgcacct cgacgacgac ggccgggtgc cggtggtgtt cttctccacc
     2341 gacatcgacg ccatcgcgga gatctccctc gccgggcacg ccgggcgggt gaccgagatc
     2401 gccgccgggc tcggccacat gggcaagacg gcctaccacc tggcgatgga cgcggtgatc
     2461 gaccactacc tcgactcggg ggcgacggac ccggccctgg tcgtcttcca gaccgacggc
     2521 ggcccggtca gcaaactcgc ggcggagcgg tacctctgca aggcggcccg gctgccgctg
     2581 ttctggcagt tcgtcggctt cggcaacacc cgcagctccc agttcgactt cctgcgccgc
     2641 ctggacgagc tgcccgtgcc gggccggcgg gtggtggaca acgcgggcta tttccacgcc
     2701 gggccggacc cgcgcaccgt cccggacggg gagctgtacg accggctggt cgccgagttc
     2761 ccggcgtggc tggcggccgc gcgcggggcg ggcatcgtgc gcgcctgacc gcccggcgcc
     2821 gccgccaggc gctttcatgg acgtatgacg cacaccagct gggccgtctt cgagaaggcg
     2881 gaaccggagt tcgcggcggc cgtcgaggcc cgcttcgctc agtacccgca ccatgtcctc
     2941 gccacgctcc gcaaggacgg ctcgccccgg gtcgccggcc tcaacgtcga catccgcggc
     3001 ggggagctgt ggctcggcat gatgcagggc tcgatgaagg cgcgggacct ggagcgcgac
     3061 ccgcgcttcg cgctgcacac caacccgggc gagggcgaga cgatgccgga cggggacgtg
     3121 cgcatctcgg ggcgcgctgt ggagctcctg gacccgcccg agctgcaccg gtacgcggag
     3181 gagagggact ccccgcaccc cttccacctc ttctacgccg acctgaccga ggtcgtccac
     3241 atcgggatcg acggcgacga cctggtgctg cggacctgga ccccggcggg cggcgtgcac
     3301 accgtccgtc ggggcgacga cgacgagccg ccgcacgagg agccgacgac tagctgaagg
     3361 ggccggggcc ggggccgggg ccgcccgggc gggcgagagc ggcgggctcc aggtccagcc
     3421 agctgcggtc gatcttgagg gtgacatcgc cgtacgtggc ctcgtggtcc ccgcggaact
     3481 ggtgggcccg gcgccgcccg gcccacagct tcttccccgc gggcagcccc atgtccgcgt
     3541 cggcgaccga ggcccggccg ttccagacgg ccacccagat cacgtccggc atggcttcgg
     3601 gagcctggtg gtggtgggca ctcagggcct tgacgcccga gctcgccgcg acgtaggcgg
     3661 cggagcggta gccgagctcg tgcagccgta cggtccaggc cgtcagatag gcgacgaccg
     3721 gggcgtccca ggtggcccgg tcggtgtagt tctccaggtc gttgtagagc agcgtgccgc
     3781 cggccaggcc cagggagcgg gcggcctgag cggcgccttc ggcagcctcc ttgccctgct
     3841 cgttggcctc ggaggggtcg gtggacaggc cggtgtcggc gttgtgccag ggctgcgggc
     3901 ccacccagat cggcatcagg tgccagccgg cgccgatctg gcgccggagc cagttcgccg
     3961 tgagccgggg ctgggcgcag gcgcgggcgc ggccgccgat gtagacgccg acggctccga
     4021 agggggaggc gccgtgccag gcgtccatgg cgcgctgggt gggggcggtg caggtgtcga
     4081 aaccctggcc ggtgaaggcc tcctgggcgc cgcgggggcc ggcgaggacc gcgccggcgg
     4141 ccgcggcggc cgcggtgcgt gcggcggcgg cggtcgcggc gggagcggcc ggagtggcgg
     4201 gagcggggcc gggggcggtg cggagctgcg cgagcaggcc ccgtacgacg ccgggaccgg
     4261 acccgtacga gagcgtggcc atcaccccgg agcggcgcag ggcgtagcgc acctcgttgc
     4321 tgtcggcccg ggtggcgggc agcgcccgca ggtcgtcggc ggcgacggtc gggatgtcgg
     4381 cgcgcggcgg ggtgtcgtcg aggggctcca ggtgcagggt gtcggcgcgg gtgcggacgg
     4441 cgcggccggt gcactcggcc tgggttccgg cgtgcccgag gtagagggag ggcaggtcga
     4501 ggcgcaggca ggcgccgggg ttccggtcga ggtccacgac gcgccagcca gcggggaggg
     4561 tgagccgcag cccgcggtag tcgacggtcg gaccggcggc gggaccggcg ggaccggcgg
     4621 cggcgggcac ggccggcgcc agcagggcgg tgcccagcaa gccggccgac agcagccgcg
     4681 ccgacagcac acgggcgcgc ggggcacggg agggcggcgt tcggaaaggc gacgttcggg
     4741 aggacgacgt tcgggagggc atgtgaccca cagttaccag agcgcggcgg ccctcaactt
     4801 cgctgcggga agccccagat gggccgtacg gccgatgccg cgcccgcccc cgggccgggg
     4861 ccgcctcacc cgtacgagtg aggcggcccc ggccctgtca cggcggccgg tgcgctcccc
     4921 cacggggcac cgaccgccgg tccccgcccc gtcagcagga ggaggccccc gccggcggct
     4981 tgaagacggc gctcagggcg cggtcggcgt cgagcgtgac caggctccag tccagcgagc
     5041 cgcccggcat gttcagtccg tccggcaggt cgtcctcggt gatctcctcg ccgacgtaga
     5101 cgacggacag ggtcccggag cagcccttcg gcggcggggg cacgctgccc acgacgcggc
     5161 cgtcgcgcgg gccggcggag agggtggtgg actcgatcgg cgcgtaggtg aaggagtagc
     5221 gggcgctcga tccggacccg gcgcgggtca tctcgacccg gaaccagctg agctggaacc
     5281 ggaccgcctc gcagggccgc tgcgtctcct tcgcgaggag gtagaccccg gagtcggtca
     5341 tgaagaacgc gggcgaggct ccgtggctgc tgtcgctgag gtccttgaag taggccagcc
     5401 gttcggccgt ggtcatgtcc gtcgtgggca cgcacagccg gttgcgggtg ctgctgggag
     5461 acggcgaggg tgccgggtcc ggcgacgggg agagcgggct cggcgaggcg ggcacggacg
     5521 ggggtgcggt ccgtgtctgg cccccgcccc cgcacccggc gagggcgagc agcggaacgg
     5581 tcaggagcgg gacgatcagc ccaggtaatc ggcgcatacg gcctcctctt cgggcggagc
     5641 cgggactgct tcgatgctgg cagcccgcgt ccggcggcgg tatccgtaga accgcctacg
     5701 tatccccggc gccggttgcg ggtaccggtc agctggggag ggaccatgac ggacaggact
     5761 ccactggtcg gccgggaggc cgaactggac cggctggacg cggtactcga cgggccgggg
     5821 ggcccgccgg gtgtcgtcga cctgaccggc gcggcgggca tcggcaagag ccggctgctg
     5881 accgaggtgt gcgggcgggc cgaggaacgc gggctgacgg tgctgcgcgg ccgggccacc
     5941 gagtacgaac ggcacattcc gttccgggtg ttcggcgacg cgttcgcgga tctggacccg
     6001 gaactcctgc gcggcctggg cgcgccgggc gcggcctggg cggcctccgc cggggcggcg
     6061 gcggacggga tctcggcgaa ccccgccgtg gaccccaccg gggcgggggc gggggccggg
     6121 gcaggggtcg gagccggggc cgaggcggga gccggggccg gggccggggc aggcgccggg
     6181 gccggggcgg gggccggggt gtcggccgtg gaccggttcg ccgcgcaccg ggcgaccgcg
     6241 cggctgctca cggcgctcgg cgggcggacg ggggccgggc tgctgatcgc cctcgacgat
     6301 ctgcactggg cggacccggc ctcgctggag ctcctcgacc acctcgtgcg ccaccccctg
     6361 cgcgccccgg tggtcatcgt cgtggcccgg cgggaccggc agaccgcgcc gtcgctcgcc
     6421 gccgcgctca cccggggcgt cgacacgggc gccgtgctcc gcctggacct cgggccgctg
     6481 accgagcggg cctgcgtcga gcagctcgcg cccgggctgc cgccggaccg ggccgcccgg
     6541 ctgtacgcgg ccagcgaggg caacccgctc tacttcctga ccctgctcca gggccaggag
     6601 cagggccgca gcggtccggc cctgccgccg ggcgggctcg gcgcgctgct gctcgacgag
     6661 ctgacgccgc tgagcgccgc gcagcgccgt accgccgagg cggtggcggt actcggcgac
     6721 caggccacgc cgccactgct gctcgcgctc accgagcccg cgtccgcgtc cggtcccgag
     6781 cggctcgacg ccgacctcgg cgtcctggcc cggcgcgacc tgatacggcc gcgcccgggc
     6841 ggtgtctggt cgctgcgcca tccggtgctg cgggccgcgg tgtacgagga caccgggccc
     6901 ggccggcgcg ccgcgctgca ccggcgggcg gccgccgcgc tggcggcggc gggcgcgccc
     6961 gcgaccgtac gggcccatca tgtggagcgg gcgctgaccg actgggagcc ggaggccgcg
     7021 gccgtcctgc tggaggcggc cgagcagtcc gagacgaccg cgccggcgag ctgcgcgcac
     7081 tggctggagg tggtgctgcg ggtgctcccg gacacccccg gccatgcggc gcgccgccgg
     7141 gacctgatgc tgaagcgggc gcgggcgctg agcgtgtgcg gcgagttacg ggcgagccgg
     7201 gacctgctgc acgaggtgat cgcggggctc cccgccgacg acggcagcgg ggtgcgcgcg
     7261 gccgccgtca cgctgtgcgc gtcgatggag cgccacctcg gtcagtaccg ggcctcggtc
     7321 gcgctgctgc gccgggcgct gtcgcggcgg cccgctcccg ctccggccga cgcggtcgcg
     7381 ctgggcctgg agctgggctc gtccgcgccg cacgccctgc cctttccggc ggtgcgcgcg
     7441 gaggtgctgc gcaccctgga gctggcccgg gccctgggca acgagccggc cgcggcgggg
     7501 gcgctggcgg tgtcggcgct cggggaggcg tacgagggga acacggccgc cgcgcgggag
     7561 ctgacggacc gggccgccgc gtgcgtggac gcgctgacgg accgggactt ggcggaccag
     7621 tgcgagccgc tggcccggct ggggtgggcg gagttctacc tggagcgcta cgaggacgcc
     7681 gagcggcacg cggaccgggg gcttgccatc gcccgccgcg gcgggccgct gcacctgctt
     7741 ccgcacctgc tgatgtgcaa ggcgatcgtc cacacgcacg cgtgccggct gccgtcggcg
     7801 ctggacctgg tggacgaggc ggagagcatc gcccggggca tcggcagcga cgagctgctc
     7861 gggctggtcc tcgcgaacaa ggcgcaggtg ctgatcgcgg cccgtccgcc gggggacgtc
     7921 agcgcgctcg cggcggcgga ggaggcggtc gcggcggccg gtgcgcggac cagttggtgg
     7981 acctcgctgg tgtggtgcgt catgagctac gccgcgctgc acggcggcga tccggtgcgg
     8041 gccaggtcgg cgatgctgcg ggcgggcggg gcggatctgg cggggctgca gccgtcgatg
     8101 cggccgctgt tcctggaggc cctggtcacc gcggccgtca cgacggggga cctggccggg
     8161 gcgcaggagt gggccgcgct ggccgggcgg gacgcggagc ggctcggcct gcccgtccag
     8221 cgagcggcgg cgctgcgctg cgcggggcag gtgctggcgg gctcgggccg tccggccgcg
     8281 gcggcggagc ggttcgcgcg ggccgccgag gaggcgggcc gctcgggcgc ggtgctgtgg
     8341 gaggcccagt ccctgctgat cggcgcgtcc ctgacggcgg aggcgggcga cccggcgacg
     8401 gcgtcggcca tgtggcggcg cggccgccgc ctggccgaat cgggcgggtc cctgctcctg
     8461 acgggcctcg cggacctcct cctcccgccc cctcccccgc cccgcgtacc gggcctcacc
     8521 ccgcgcgagc acgagatcgc cgccctggtc gccgagggcc tcaccacccc ggccatcgcg
     8581 gcccgcctct acctgagccc gcgcacggtg gacacccacc tgtcccacat cttccgcaaa
     8641 accggcgtca ccacccgctc cgccctagcc gccctcactg cccgccacct gccgtgagcg
     8701 ctccctcttc ctgttacggt catccgttcg ccgaggaggt cctgatgaac agatcgctgc
     8761 ccatcgctgc cctggtggat ctacgccgtc agccgatgga agacgtgctg gagcgcgtgg
     8821 aagaggccct gcgcgtgcgg ttggaccggg aggcgctggt acgcaagcgc cgttccctgg
     8881 ggggccgtac ggaacggggt acgtgggtgc gtatcgagcg gcggggattc gagcggatcg
     8941 gcccgcaggg ctggaacggg accgaggcag ctgccgttct gcaaggggtc gcgatgcccg
     9001 agtggtaccg gggcgtggcg tggcgcgagc cgggcgaacc ggtgatgtgg cgtgcggatg
     9061 agctggagct gctcgcgtcg gcgtctgtcg ccgggggcgc cttggtgctc gaagacccgg
     9121 gcctaccgga tgcctggtgg gcagcgctca acgcctcgct ggacgccctc gcggaccagc
     9181 agacgccgcg aatcgcgacg ccggacacgg tgacgatcac ccaggagcag gtgacgcgga
     9241 cgctcggcga ggtcttcccc ggcgtcaccg atacgcggat cgagcggtgg gcgccggctc
     9301 acgccgatct gacctgggcc aatgtgatgg cgccggagtt ctccatcgtc gactgggagg
     9361 actggggcat ggcgccccgg ggcctgacgg tagttgaaac gcgaaggccc cgtcatccgt
     9421 gagcggggac gacgggggcc tcagcggtcg gttcaggcgg actcagtggc gctcaggaag
     9481 tcgtcggcgg tggcgtccat caggatctcg tcacaggaac ggccaagcca gtagccggac
     9541 tgccgcaggc ggccagcaga ctggaaaccg gccttttggt aggccgtcac gcccgcagta
     9601 ttggcctcca gcaccttgag ccacaccatg cgcagcgcgg cgtactcgaa ggcccagcgg
     9661 agggtcaggg aggtggcctc ggtggccagg cccttccccc gggattcggg ggcgatgagg
     9721 atgacgaact ctgcggtccg cactgccgag tcgatctgca aggtggtgag tccgaccggg
     9781 gcgtagtcgt cggcggtgat cacctcgaac tgagcgtagt cgcggttgcg gccctggccc
     9841 tcccagccgc ctgcgcggac ctcccaggac tgggttacct gggtgccgta gcccaggatc
     9901 gtggcggggt cgttctccca ccggtggtag tcggggaggt ggtcgcggtt ggtcatcgcc
     9961 aggctgacgc gctcaccggg cagcaggatg tgcggggcac tcatcgcggt tcggctccag
    10021 aggagttggc tgtgttgatc ggggtgtagt cgccagtgtg cccgggttcc tccaccgggc
    10081 gtccgtgttc gtcgcagatc caggcgtgaa gccggatcgg gtcggcggcg acgccatggc
    10141 gccacgcgtt gccacgaccg ccggccgcga ggagcacgga ggccgcggtg gactcttcga
    10201 ggcaggcgac ccgggccgga atggcacgtg cggcccagcg gacggagcgc accgccgtgc
    10261 gagcgtgaac agcgctggcc ggaggcagag caccgccgac gctggcgagg cgcaccagac
    10321 gcccgaacct gtactcagaa cggcctgtct ggcggacggt gagcgtaaga gcgacgcagg
    10381 ccagcgcggc cacccgccaa ggccagggcg gggagccgtg ggattcgagc cgggccgccg
    10441 tctcgtgggt gccccaagac gcgccagggt tggtgacgac tacaggcttg ggtgcgttgc
    10501 cctgccggac ggcggacagc cattcatcca gagcaccgcc cgtcaggacg atggtggcgc
    10561 cagtgcggta gttgacgatg actccggcgc ggtccgtgac ggcggtccgg gtctctgctg
    10621 tgggaacggg aatcacgcgg ccctctcctc ccaagtgatc cactgatcga ctttctcggc
    10681 ggccctcaac cacagttctg ccccgagggc gggttcgagt cggccccacg ggatgtctac
    10741 tcccaggacg gcgcggcgta gcgtcgcccg gaccatctcc gggttgatga gcccgaggtc
    10801 tgccagatgc ccgtctgcca agtcgagcgc acgttgcagg ttgacccgca gcccgtggtg
    10861 gtggtcgacg gcgaacatgc ccttggcgcc ccggcggacg acgggcgggg gcagcaggcc
    10921 ggccacgacg tcggagagca gcggcttgta ccggcgagcg gaccagcgtt cgacagcggg
    10981 ggccgccaat gcagcttcca cgacgcgggt gtccgtgaac ggattgtgca tctcgatgcc
    11041 gtgcgcggca gcgagctggt tttcagtcgc ggcggtgcgg ccgacgtagc gggcttccgt
    11101 cagtagggca cggtccgcgt gccccatgtt cagcgtgtcg ggataggccg ccgagacggg
    11161 tgcggccagc tcctttgcgt agtcggtcat ccacggcatg ggccccgagg agccggccag
    11221 cgtgcgaggc cgtcgcaccg cgttcacgag gaaaggccaa gggctctgcc ggtagagacg
    11281 agcccaggtc tgcgcgtcgg ccgccagccg cagccagtga ccggaacggg cgaggtccgc
    11341 cacatggacc ggcgggggca tgaacaggtt gtccccaccg tctccggtca agtggaccac
    11401 ggcgccgtgg tcggcgagga accgcagttg cgcggtgaac tgcgcgatgg tgatggcgga
    11461 gggcgcgggc tcatcggtga gcggtaaggc gtcgagatcg ctgaacggga ggtgagagtc
    11521 gtccaaggcc atgaactcat gccggatcgc gggataggcc cgcgccacca gacatgcgtg
    11581 gtcgacatcg ccgcccgcct tgattccttc ggggtggtag gtaaccgcgg tcaccggccc
    11641 gcagcgggcg gccagcgccg cgagggcgct ggaatccaga ccaccggaga ggtcggagga
    11701 aaccgggcgt ccggtgacac ggatgcggac gccctccgcc aggtcctcgc gtaaccagtc
    11761 caccgcttcc tctcgcgtga gtgcgggtgg cgtccagtaa gggacaggaa caggctcagc
    11821 acggaggcca gcggcgatcc ggtggccagg cgccacctgt tctacgttgg accaggcgga
    11881 gaaccccggg gtccatcctg tggggtccac gaggtgggca gccatccatc cggcatccgg
    11941 cagcgatccg cacagagcag ccaaggcgtg cgcgcttgac gcccacacgg tcgagccgtt
    12001 gaaggtgcag gtatagagcg ggcaagcccc cgcagggtct gcccagaccg tcagggcgtc
    12061 atggccatcg tcgtagagca acgtgtaagc gcccgcccag gccgttgccg ccgaatcgag
    12121 cgagcggagg tctccggcct gggctagccg atccaggtcg gcatccatgg cgccgcaggg
    12181 cccgaagacg accagccgcc ttccatgggg accgtcgacc agccgaaccg gtgcaccggc
    12241 ggaccacacc ggagggtctg gccagagaat ctgcgcgccg actgggaccg tcggtctgga
    12301 ggccgtcctg aggtagccgc cgaaccagcc catgtgatca cctccgtgaa atggggcgcg
    12361 gcggcacccg gggcagggtg ccgccgctgg gggtcaggcg gagtacgggg agcgcttgtt
    12421 ctcgatgctc tcgctggtgc tgcccttcgt gagggcagcg gcgtcgccga ggggcacgat
    12481 ctcctcgttc tcgtcggggt cgctcgcctt gatgatctcg ttcattgctg ttcacctttc
    12541 ttgttggctg gtgatcgcag cgggggttcc cgttgcgctg gtgcgagctc cggggtccgg
    12601 tttcgcattc ggaaccggga ggggatcagg ggtgccgtac ggctatgagg tggcgtagat
    12661 gccagcggcg tacaggaccg gcgagccgaa gagcatcgcc aggtacaggg ggccggcgaa
    12721 ccgtccgaat cggcggatga gccaccgccc tgaggcatcc acttcgtcgc cccgggcgtg
    12781 acgacgaccg ggcgaagggc gcgtgccgag cccggaccga ggcagcgcgc gcattcacac
    12841 ggcgggaagc ggacgggatt ggccaggatg gtcaggggac tgatgtcgcg gacttcgcac
    12901 cgcaccgacc acgtacggcc cgaatcccga gacacccgca gcgtcatccg agcccgcgac
    12961 tcctcgccgc cggggccccg catcacagcg tgctcccgct aggcggtgag ggtccgagca
    13021 tccgactgca catgagtggt ctccctgcct gaggtggttg gggccgacta cacacctggc
    13081 aaccggggcc aattaccggc ggccgacaat gatgctgcgc tgcccgtcag tgcgttccca
    13141 ccgcgtttgc gggacgtttg ggacgtgcca ccactacggt tcgtcccgtc cctgacgtcc
    13201 ctgggaggcg aactgtgaat cacgctctgc gtagggcaat ggtgaatgcc aagatgaccg
    13261 aaaagcagct cgcagaggtc tgcggagtcg atgccaagac cgttggccgt tggatcaccg
    13321 acgccaaccg aatcccccac gctcggcatc gatgggcggc ctgcgaagca ttaggtgaag
    13381 aggagaagat cgtgtggccc aacgccattc gctcggcctt cgcgacgggg ccggatcgag
    13441 agatcgtgca ggtcttcccc taccggtcgg cggcgccggc gagtctgtgg cgctcgctgg
    13501 taaccaaggc ccagagtgac ctggtctttg ccggttacac caactacttc ctgtggttgg
    13561 agcaagccaa cctcggcggc gcactgcggc gtaaggccca ggcgggatgc agggtccgat
    13621 tcctgatcgg ggacccggac agcccaatta cggccgctcg cgaggaagaa gagggggtgc
    13681 ccctcacgct ctccacgcgc attgccgtca cgctggccga gctggaaaag ctccgtgacg
    13741 tggccggcat cgaggggcgt tttgagtcag gccacgtgaa tctctcggtc ttccgcttcg
    13801 acgacgagat gatcgtgaca ccaatcctcg cccgcagggt cggtcacgac tcaccgatga
    13861 tgcatctccg acgctgccag gccgacggga tgttcgatcg ctttgccgct cacgtcgagg
    13921 agctgtggag ccgcgggcgc gacatccggg aggccagaca ccatgcccag gcgtgactac
    13981 gaggacgacc cgaacgcccc caaggcgaac agcctggtgc cggcggcgtc agcggtcgtc
    14041 gtggacgacg aaggccggat cctcttgcag cgccgcacgg acaacggcat gtgggccttg
    14101 cccggcggaa agatggagct gggcgagtcc ctcggcgagt gcgctgcccg cgagacgctg
    14161 gaggagaccg gtatgaccgt ggagatcacg ggcatcgtcg ggacgtacac caacccgggg
    14221 cacgtgttcg cctacgacga cggcgaggta cggcaggagt tctccatctg cctgctcgcc
    14281 cgcccgacca gcgggacact tcggacgtcg gacgagtcat tcgaggtcgc gtggttcacc
    14341 cctgacgagg tggacggcct cccgatggtc cccagcatcc gcaagcgcgt caacgactgg
    14401 cggatggggg cgggccccgt cgtacgctag agctgcctgg tgagggtcgg aaaggcggcg
    14461 gctcgcatgc cgtcggcgga cgcacgcgat cagctgcgta cggggccgga cgagctctcc
    14521 gacggatctc ccgcgtcagg ctggacgcgg agatgcgcgt tcgcccccga cgcctgaccc
    14581 cgcgaacgcc acagcgcccg tcatccctgg tcggggacat gacgggcgct gtgtcggagt
    14641 gccgtacacc gttgtacgga ccgaatgagg ggtcccccca gagggagggg taccgcgcgc
    14701 cgccggtcgg aggccggcgc agccgggcga agcccgggag gccgccccgc ggccgaacgg
    14761 cgcgagcccg gcgtccagaa ggagccatga cgggcgctgt gtcggagtgc cgcacaccgt
    14821 tgtacggacc gtatgagggg ccctccccgc ctggggcggg gaggggtgac gggttacacc
    14881 atcagggagc ggtccgtcgg cttgaccggg tacgggaggg cgctggtgcc ggtcaggtag
    14941 cggtccacgc cgcgggcggc cgagcggcct tccgcgatgg cccagacgat gagcgactgg
    15001 ccgcggcccg cgtcgccggc gacgaagacg ccgtccacgt tggtcgcgta ggaggcgtcg
    15061 cgctcgacgt tgccgcgcgc gtccagctcc aggccgaact gctccaccag gccgttggcc
    15121 tggtcggtgc cggtgaagcc catcgccagg gtgaccagct gcgccgggag gacgcgctcg
    15181 gtgcccgcct tctggaccag cttgccgtcc tcgaaggcga cctcgaccag gtgcagggcc
    15241 tggacgttgc cgtcctcgtc gccctcgaag tgggtggtgg agacggagta gatccgctcg
    15301 ccgccctcct cgtgggccga ggtgaccttg tacagcatcg ggaacgtcgg ccacggctgg
    15361 ccggtgggcc ggtcctccga cgggcggggc atgatctcca gctgggtgac cgaggccgcg
    15421 ccctggcggt gggcggtgcc cacgcagtcc gcgccggtgt cgccgccgcc gatgacgacc
    15481 acgtgcttgc cctcggccgt gatcggcggg gccatgaagt cgccttcctg gaccttgttg
    15541 gccaggggca ggtactccat cgcgaagtgg atgccgccca gttcacggcc cgggaccggc
    15601 aggtcgcggg agacggtggc gccggccgcg acgacgaccg cgtcgaaccg cttgcgcagg
    15661 tcggtcgcgg acaggtcgcg gccgatctcg atgccggtgc ggaacttggt gccctccgcg
    15721 cgcatctgct cgatgcggcg gttgatgtgc accttctcca tcttgaactc ggggatgccg
    15781 tagcggagca ggccgccgat gcggtccgcg cgctcgtaca ccaccacggt gtggccggcc
    15841 cgggtcagct gctgggccgc ggccaggccg gcggggcccg agccgatgac ggccgccgtc
    15901 ttgccggaca gccgctcggg cggctgcggg gtgacgccgc cgttgtccca cgccttgtcg
    15961 atgatcgaga cttcgacgtt cttgatcgtg acggcgggct ggttgatgcc gagcacgcac
    16021 gccgactcgc agggagccgg gcacagccgc ccggtgaact ccgggaagtt gttcgtcgcg
    16081 tgcaggcgct cggccgcggc ggaccagtcc tcgcggtacg cgaagtcgtt ccactccggg
    16141 atcaggttcc cgagcgggca cccgttgtgg cagaacggga tgccgcagtc catgcagcgg
    16201 ccggcctgct tgctgatgat cgggagcagc gagccgggaa cgtagacctc gttccagtcc
    16261 cccagccgtt cggcgaccgg acgggaacag gcggtctcgc ggccggtggt gaggaagccc
    16321 ttcgggtcag ccatgggtcg ccgcctccat catcttctcc gtggtctcgg actccgagag
    16381 tccggccagc tcagcggcat ccttggcggc gagcactgcc ttgtacgtgg tcgggatgat
    16441 cttgctgaag cggtccgccg cgacggacca gtcagccagg agcttcgcgg ccacggtcga
    16501 gccggtctcc tcctcgtggc ggcgcacgac gtcgtgcagc cactgcttgt cggtgtcgga
    16561 cagctcggtc tcgaccgcgt ccgtgttgcc gacgttgacg tggtgcgggt cgaggtcgat
    16621 gacgtacgcg acgccgcccg acatgccggc cgcgaagttg cggcccgtct cgcccaggac
    16681 cacggcctgg ccgccggtca tgtactcgca gccgtggtcg cccacgccct ccgagacgac
    16741 cagcgcgccc gagttgcgga cgcagaagcg ctcgccggtg cggccgcgca ggaacatctc
    16801 gccgccggtc gctccgtagc cgatggtgtt gccggcgatg gtcgagtact cggcgaggtg
    16861 gtcggcggcg cggtcggggc ggaccacgac gcggccgccg gagaggccct tgccgacgta
    16921 gtcgttggcg tcgccctcca ggcgcagcgt gacgccgcgc ggcaggaagg cgccgaagga
    16981 ctggcccgcg ctgccggtga aggtcaggtc gatggtgttg tcgggcaggc ccgcgccgcc
    17041 gaacttcttg gtgacgtggt ggccgagcat ggtgccgacg gtccggttga tgttgcggat
    17101 cgcgacctgg gcgcggaccg gctgggccgt ttccgcggtg tcggcgttca gggcctcgga
    17161 ggcgagctcg atcagctcgt tgtcgagggc cttctccagg ccgtggtcct gctcgatcag
    17221 ggcgtggcgg accgcgccct cgggcagctg cggcacgtgg aagaggggct ccaggtcgag
    17281 gccctgcgcc ttccagtgcg tgacggcctt gctggtgtcg aggagttcgg cgtggccgac
    17341 ggcctcctcg atcgtacgga agcccagctc ggcgaggatc tcgcgcacct cctccgcgat
    17401 gaactcgaag aagttcacga cgaattcggc cttgccggag aaccggtcgc gcagcaccgg
    17461 gttctgggtg gcgatgccga ccggacaggt gtccaggtgg cagacgcgca tcatgacgca
    17521 gccggagacg acgagcggcg cggtcgcgaa accgaactcc tcggcgccga gcagcgcggc
    17581 gatgacgacg tcgcggccgg tcttgagctg gccgtccgtc tggaccacga tccggtcgcg
    17641 caggccgttg agcagcaggg tctgctgggt ttcggcgagg ccgagctccc aggggccgcc
    17701 cgcgtgcttg agggaggtca gcggggaggc gcccgttccg ccgtcgtggc cggagatgag
    17761 gacgacgtcc gcgtgggcct tggagacacc ggcggcgacc gtgcccacgc cgacctcgga
    17821 gaccagcttc acgtggatgc gggcgaccgg gttggcgttc ttgaggtcgt ggatcagctg
    17881 ggccaggtcc tcgatggagt agatgtcgtg gtgcggcggc ggggagatca ggccgacgcc
    17941 cggggtggag tgccgggtct tggcgaccca cgggtagacc ttgtggccgg gcagctggcc
    18001 gccctcgccg ggcttggcgc cctgcgccat cttgatctgg atgtcgtccg cgttgaccag
    18061 gtactcgctc gtcacgccga agcggccgga ggcgacctgc ttgatggagg agcggcgcgc
    18121 cgggtcgtac aggcggtccg ggtcctcgcc gccctcaccg gtgttggact tgccgcccag
    18181 ctggttcatg gcgatggcga gggtctcgtg ggcctcgcgc gagatggagc cgtaggacat
    18241 ggcgccggtg gagaagcgct tgacgatgtc ggcgaccgac tcgacctcgt cgagcgggat
    18301 cgacgggcgg cccccgtcct cggcggcctt gaacccgaag agcccgcgga gcgtcatgag
    18361 gcgctcggac tgctcgttca cccgctcggt gtacttcttg aagatgtcgt accggcggtt
    18421 gcgggtggcg tgctggaggc ggaagaccgt ctccgggtcg aacaggtgcg gctcgccctc
    18481 gcggcgccac tggtactcgc cgccgatctc cagcgcgcgg tgcgtggccg cgatgccgga
    18541 ggccgggtac gccttggcgt ggcgggcggc cacctccttg gcgatgacgt ccaggccggc
    18601 gccgccgatc ttggtggcgg tgccctcgaa gtacgaggcg acgaactcct cgttcaggcc
    18661 gacggcctcg aagacctggg cgccgcggta ggaggcgacg gtggagatgc ccatcttgga
    18721 catgaccttc aggacgccct tgccgagggc gtagatcagg ttcttgatgg cctgctccgg
    18781 ctccaggccg gacaggaagg taccggcgcg cagcaggtcc tcgacggact ccatggcgag
    18841 gtacgggttg accgcggcgg cgccgtagcc gatgagcagc gcgacgtggt ggacctcgcg
    18901 gacgtcaccg gcctcgacca gcaggcccac ctgggtgcgc tgcttggtcg cgatgaggtg
    18961 gtggtggacg gcggaggtga gcagcagcga cgggatcggc gcgtgctcgg cgtcggagtg
    19021 gcggtccgag aggacgatca ggtgggcgcc gccggcgatg gccgcgtcga cctctccgcg
    19081 gatctcctcc aggcgggcgg ccagcgactc gccgccgccg gagacccggt agaggcccgc
    19141 gagggtggcg gccttcatgc cgggcatgtc gccgtcggcg ttgacgtgta tcagcttggc
    19201 gagctcgtcg ttgtcgatca ccgggaaggg cagggtgacg ctgcggcagg acgcggaggt
    19261 cggctccagc aggttgccct gcgggcccag cgaggacagc agcgaggtga cgagctcctc
    19321 gcggatggcg tccagcggcg ggttggtgac ctgcgcgaac agctgcgtga agtagtcgaa
    19381 gaggagccgg gggcgggcgg acagggccgc gatcggggag tccgtgccca tggagccgag
    19441 cggctcgccg ccggtgcggg ccatcggcgc gaggatgacg cgcagctctt cctcggtgta
    19501 gccgaaggtc tgctggcggc gggtgaccga ggcgtgggtg tggacgatgt gctcgcgctc
    19561 gggcaggtcc gtcagctcga tctcgccggt ctccagccat tcggcgtacg gggcggcgcc
    19621 ggccagctcg gccttgatct cgtcgtcctc gatgatccgc ttctgggcgg tgtcgacgag
    19681 gaacatcttg ccgggctgca ggcggccctt gcggacgacc ttggccgggt cgatgtcgag
    19741 cacgccgacc tcggagccga ggacgacgag gccgtcgtcg gtgacccagt agcggccggg
    19801 gcgcagaccg ttgcggtcga ggaccgcgcc gacctgggtg ccgtcggtga aggtgacgca
    19861 ggccgggccg tcccagggct ccatcatcgt ggagtggtac tggtagaagg cgcggcgggc
    19921 cgggtccatg gaggcgtggt tctcccatgc ctccgggatc atcatcagca cgctgtgcgg
    19981 gagcgaacgg ccgccgaggt ggagcagctc caggacctcg tcgaaggagg ccgagtcgga
    20041 ggcgtcgggg gtgcagatcg ggaagatccg gtccagggcg ccgtcgccga aggcgtcgga
    20101 ggccagctgg gactcgcggg ccttcatcca gttccggttg cccttgaccg tgttgatctc
    20161 gccgttgtgc gcgacgaagc ggtacgggtg ggcgagcggc caggagggga aggtgttcgt
    20221 cgagaaccgg gagtggacca gcgcgagcgt cgaggcgaag cggcggtcgg agaggtccgg
    20281 gaagaagggc tccagctggc cggtggtcag catgcccttg tagacgatgg tgcgcgcgga
    20341 gagcgacggg aagtacacgc cggcctcgcg ctcggcgcgc ttgcgcagca cgaaggcctt
    20401 gcggtccagc tcgatgccgg tgctgccgtt gctcacaaac agctgcgaga aggcgggcat
    20461 ggtggcgcgg gcgccgttgc cgagcaggtc cggggtgacg gggacctcgc gccagccgag
    20521 gaccgtgagg ttctcctcgg cggcgatggc ctcgatccgc tccacggcgg cggcctgtgc
    20581 ggtgccgtcg gcggggagga aggcgatgcc gacggcgtac gcaccggcct cgggcagctc
    20641 gaatccggcg acctcgcgca ggaaggcgtc cggcacctgg gacaggattc cggcgccgtc
    20701 gcccgagtcg ggctcggagc cggtggcacc acggtgttcg aggttccgca atacggtcag
    20761 cgcctgctcg accagcgtgt ggccggcctc gccgctgagg ttggccacaa agccgacgcc
    20821 gcaggcgtcg cgctcgttgc gcgggtcgta catgccctgg ggggcggggc gaccgtccat
    20881 gggcgaccag gcggtggtgc tggggccggt cgcggagtgc gtggatgcgg aacgcatcgg
    20941 ctctcccgtc gtcgtagcgg catatgtgcg ttgccgaggg acgacgttgg ccctctgcga
    21001 aatttcgtgc aggttacatg atgacggcaa tcccgagaag cggatatgtc attccagcat
    21061 gcggacaccg cacgaaacga aagccgggac cttcgctgcc gttttgacgg tcgtcagcga
    21121 tcgaaaaata tggggcgaag ggacccgaac gggtgcttgg cgggcctcat tgcccgcagg
    21181 aggtgccttc ccggcgagag agtcgggagg gtcctggtgt gatgcccggc ggtcacacgg
    21241 ttgaaaccgc cgagtaatga actacttatg tcgtgcggtg catagtgtct cactcccgcg
    21301 ccgctcagcc tacggctcca ccgatccagg ttcccaggat gtacgtcaca ccggcggccg
    21361 cgccacccag gacgagctgg cggagtccgc tgaaccacca cgaccgcgcg gtgacccggg
    21421 cgacgaccgc cccgcaggcg aagaggccga ccagcgccag cagcaccgcc ggccacaggg
    21481 cggtcgcacc cagcaggtac ggcagtacgg ggagcagcgc gcccagcgcg aacgaggcga
    21541 aggacgacac cgcggcgacg agcggcgacg gcaggtcctc ggggtcgatc cccagctcct
    21601 cgcgggcgtg gatctccagc gcctgctcgg gatcgcgcga gagctgcatc gcgacctcgc
    21661 gggccagggc cggctcgaca ccgcgcgata cgtacagctc ggccagctcc tccatctcgt
    21721 cgacggggtg cttgcgcaac tgctggcgct ccacgtcgag ttccgcgagg accagttcgc
    21781 gctgcgaggc gacggaggtg tactcgccgg ccgccatcga gaaggcgccg gcggcgaggc
    21841 cggcgagccc ggtgatgacg atggtctgcg gggcggcggc gccgccggcc acgccggtca
    21901 tcagggcgat gttggagacg aggccgtcca tggcgccgaa cacggccggg cgcagccagc
    21961 cgccgttgac atcacggtga ctgtgattgt cacggtgggc ggtgtgcagc ggcgctgcgg
    22021 tgtcgatgat ggacatgcga agtttctccc cttttgcatg aacgggcacg gtgaggcgtc
    22081 ccgctccccc ctgaacacct cgaaactacg cacgatttct gccgcccgcc agcaaggtag
    22141 gccgtactta ccttgggttt tggggatcgg cgaccgggtg acgggggtgc gggcggggtg
    22201 tttcgcaacg agcgacaaac ctcatgtcat ggcacaaatc ccccaagggc tcaatatgag
    22261 tcccatcaag tggagaggcg cgccatggag ctgattgcat gcaatccgca ggtcctcctc
    22321 gaacgggccc ggg
//
