LOCUS       NZ_CP011664            34587 bp    DNA     linear   CON 03-MAR-2024
DEFINITION  Streptomyces sp. Mg1 chromosome 1, complete sequence.
ACCESSION   NZ_CP011664
VERSION     NZ_CP011664.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. Mg1
  ORGANISM  Streptomyces sp. Mg1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     De Novo Assembly of the Streptomyces sp. Strain Mg1 Genome Using
            PacBio Single-Molecule Sequencing
  JOURNAL   Genome Announc 1 (4), e00535-13 (2013)
   PUBMED   23908282
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUN-2015) Biochemistry and Biophysics, Texas A&M
            University, 300 Olsen Blvd., College Station, TX 77845, USA
REFERENCE   3  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JUN-2013) Biochemistry and Biophysics, Texas A&M
            University, 2128 TAMU, College Station, TX 77843, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 8.2
            Genome Coverage                   :: 30X PacBio; 80X Illumina
            Sequencing Technology             :: PacBio + Illumina MiSeq/HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 08:10:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,822
            CDSs (total)                      :: 7,726
            Genes (coding)                    :: 7,467
            CDSs (with protein)               :: 7,467
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 260
            CDSs (without protein)            :: 259
            Pseudo Genes (ambiguous residues) :: 0 of 260
            Pseudo Genes (frameshifted)       :: 109 of 260
            Pseudo Genes (incomplete)         :: 200 of 260
            Pseudo Genes (internal stop)      :: 18 of 260
            Pseudo Genes (multiple problems)  :: 60 of 260
            CRISPR Arrays                     :: 11
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:43:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1268238
            Orig. end                         :: 1302825
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011664.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Paul Straight
            (paul_straight@tamu.edu).
            Annotation modified by the submitter.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..34587
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /product="azole-containing-RiPP"
                     /region_number="8"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..34587
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="interleaved"
                     /product="RRE-containing"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..22226
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12226](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12226
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(920..2392)
                     /locus_tag="M444_RS05040"
                     /old_locus_tag="M444_05025"
     CDS             complement(920..2392)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0070069 - cytochrome complex [Evidence
                     IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0019646 - aerobic electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020555895.1"
                     /locus_tag="M444_RS05040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05025"
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="WP_037795292.1"
                     /transl_table=11
                     /translation="MIPVHLLADAPAQLLPARELMAFTLAMHITLVPLGVALPFITLVM
                     HHRGLRKSDPVALLLARRWSAVMAVQFAVGIITGTVLSFEFGLLWPGMMGRWGDVFGLG
                     FGVEAWAFFLEAILIAIYLYGWRRLPPKTHFWLGVPLPLAALMGAFGIIAANSWMNTPR
                     GFTLDGNGRPVDVTVRQAIFTPMFGPQYWHFVVAMFITAGYVVAGVYAVGWLRGRRDRY
                     HRLGFTVPFTVAAILTPVQFVLGDNIARQVFLKQPIKFAALELVWDTDTHVPEYLFGRL
                     QEDGTVKGGIKIPQLDSILAGKSPDTKVTGLSSVPASDRPTATQATIAHWAFDIMALVG
                     TALILLALWYAWCWWRHRDLPKSPWFFRCAALSGVASVVTVECGWISTEVGRQPWIVYQ
                     NMRVSEAVTPTSASALWAVFGLVVVVYLLVFGSLLGVVLKMSGRWRLADAASGPGPAGA
                     PADDPEADTPYGPRPEPAGAAPGDHRAPGSEQ"
     protocluster    2216..34587
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[12215:24587](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      12216..24587
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="2"
     gene            complement(2427..3260)
                     /locus_tag="M444_RS05045"
                     /old_locus_tag="M444_05030"
     CDS             complement(2427..3260)
                     /NRPS_PKS="Domain: PKS_KR (20-193). E-value: 1.6e-12.
                     Score: 39.7. Matches aSDomain:
                     nrpspksdomains_M444_RS05045_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020555897.1"
                     /locus_tag="M444_RS05045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05030"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_008743730.1"
                     /sec_met_domain="adh_short (E-value: 3.7e-35, bitscore:
                     120.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.3e-29, bitscore:
                     102.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTGDQTLRETPRILKGQKALVTGANSGIGKATAIGLGRAGADVV
                     VNYVAGAQEAEAVVEEIKSHGVRAYAHEADVSREDQVVAMVDRMVEEFGTIDIMVANAG
                     LQRDAAVTEMTVAQWQKVLDVNLTGQFLCAREATKEFLRRGVVPEVSRSAGKIVCMSSV
                     HQIIPWAGHVNYASSKGGVLMMMQTLAQELAPQGIRVNAVAPGAIRTPINKDAWDTPEA
                     EKALLQLIPYRRVGDPEDIANAVTVLASDLMDYVVGTTLYVDGGMTLFPGFATGG"
     aSDomain        complement(2682..3200)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M444_RS05045_PKS_KR.1"
                     /evalue="1.60E-12"
                     /label="M444_RS05045_PKS_KR.1"
                     /locus_tag="M444_RS05045"
                     /protein_end="193"
                     /protein_start="20"
                     /score="39.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVTGANSGIGKATAIGLGRAGADVVVNYVAGAQEAEAVVEEIKSH
                     GVRAYAHEADVSREDQVVAMVDRMVEEFGTIDIMVANAGLQRDAAVTEMTVAQWQKVLD
                     VNLTGQFLCAREATKEFLRRGVVPEVSRSAGKIVCMSSVHQIIPWAGHVNYASSKGGVL
                     MMMQTLAQEL"
     gene            3520..4017
                     /locus_tag="M444_RS40890"
                     /old_locus_tag="M444_05035"
     CDS             3520..4017
                     /EC_number="2.7.1.12"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046316 - gluconokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014134714.1"
                     /locus_tag="M444_RS40890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05035"
                     /product="gluconokinase"
                     /protein_id="WP_047960921.1"
                     /transl_table=11
                     /translation="MGVSGSGKSTVGRLLAARRGVPFVEGDDFHPAANIARMRAGHPLD
                     DAAREPWLTALTEAVREVVRAGEGAVVSCSALKRAYRDRLREAAPAVWFLHLTLDRAVA
                     HARVAGRAGHFMPARLLESQYEVLEPLGADEDGLTLDAGAGTDSVLRRAGEALAGFEAR
                     SV"
     gene            4078..4620
                     /locus_tag="M444_RS05055"
                     /old_locus_tag="M444_05040"
     CDS             4078..4620
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151051.1"
                     /locus_tag="M444_RS05055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05040"
                     /product="hypothetical protein"
                     /protein_id="WP_037795293.1"
                     /transl_table=11
                     /translation="MSTSMLIAVIVIAAVLVIALAVGLWTRSRRRHLRSRFGPEYDRTV
                     EAEGGRKAAERELRSREARHDALEIKELPPERRKQYTEEWSGVQEAFVDRPERSVGEAD
                     ELVTRLMRERGYPTEDYSGQLRDLSVEHGRTVEHYRAAHDVKVRSGAGQTTTEELRGAM
                     VHYRALFEELLSDQRSR"
     misc_feature    complement(4127..4142)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            4622..5203
                     /locus_tag="M444_RS05060"
                     /old_locus_tag="M444_05045"
     CDS             4622..5203
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151052.1"
                     /locus_tag="M444_RS05060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05045"
                     /product="hypothetical protein"
                     /protein_id="WP_037795295.1"
                     /transl_table=11
                     /translation="MRDHGERDARADEAGLTTEDIAHPQAGAPAATTREDERQQVPVYP
                     GEATADPRDAAEGIRETDPGTREADDGTGAPGRAPTEQWDGEPGRATTERGAVDAPAAD
                     EEPLLGAPDAEGYRKAWSEIQGRFVDDPQEAVRSADALVAEVMQTLARTFSARKQGLEG
                     QWGQGGQVATEELRLALQQYRSFFNRLLNT"
     gene            5306..5536
                     /locus_tag="M444_RS05065"
                     /old_locus_tag="M444_05050"
     CDS             5306..5536
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487647.1"
                     /locus_tag="M444_RS05065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05050"
                     /product="DUF5133 domain-containing protein"
                     /protein_id="WP_037795297.1"
                     /transl_table=11
                     /translation="MLMAHPALLPAAVREYETLSLLNALEGSPRTVRRIEELSALLCTA
                     TGTGSAEAAVVAARYRLPGAGTFDDSVIPAR"
     gene            5628..6293
                     /locus_tag="M444_RS05070"
                     /old_locus_tag="M444_05055"
     CDS             5628..6293
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884066.1"
                     /locus_tag="M444_RS05070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05055"
                     /product="HAD family hydrolase"
                     /protein_id="WP_037796970.1"
                     /sec_met_domain="HAD_2 (E-value: 2.3e-26, bitscore: 91.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRAALFDVDGTLVDTNHLHVTSWWEALRQAGHDVPMHAIHRALG
                     LPGEDLLSHLLGEERDTGGDGALSAAHDTLYATYFERLPRLRSADELLRTLSRRGWRVV
                     LVTSAGGGELDALRRAIGADDALTATASADDVERGKPAPDPVRHALELADASAHGSVFV
                     GDSVWDMKAATRAGVRPVGFLSGGIPRHDLEAAGAGPVYRDPADLLEHLDASPFGVAG"
     misc_feature    complement(5663..5678)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            6338..6760
                     /locus_tag="M444_RS05075"
                     /old_locus_tag="M444_05060"
     CDS             6338..6760
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004991266.1"
                     /locus_tag="M444_RS05075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05060"
                     /product="YjbQ family protein"
                     /protein_id="WP_037796972.1"
                     /transl_table=11
                     /translation="MTDTFTTRTLDVTTGSGETVHDLTSACAEFLSEAARGRDGLLNVF
                     TPHATAGLAVIETGAGSDDDLLDALRTLLPADDRWRHRHGSPGHGRDHVLPAFVPPHAT
                     LPVVRGELALGTWQSVVLVDTNRDNPERTVRLSFLG"
     gene            6877..7146
                     /locus_tag="M444_RS05080"
                     /old_locus_tag="M444_05065"
     CDS             6877..7146
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127827.1"
                     /locus_tag="M444_RS05080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05065"
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="WP_037796974.1"
                     /transl_table=11
                     /translation="MGIIAWIVIGLLAGIVAKALLPGRDPGGIIITILIGIAGALLGGW
                     LGKVLFGVDSIDGFFEVSTWVAAIVGSMILLLAYRMVSGGGRRR"
     gene            7196..7687
                     /locus_tag="M444_RS05085"
                     /old_locus_tag="M444_05070"
     CDS             7196..7687
                     /GO_function="GO:0043169 - cation binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015575510.1"
                     /locus_tag="M444_RS05085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05070"
                     /product="hemerythrin domain-containing protein"
                     /protein_id="WP_037799251.1"
                     /transl_table=11
                     /translation="MTVQHDVVAVILKDHRTMEDLLRRMRSVESDRAKALEQFSALLIA
                     HGEAEEAKVYGALKRFKDVDNEEVEHGAEEHAEGNAALLALLEVSEVGSDRWDERLEDL
                     VKAVSHHIDEEERTILNGARENVPDERRAELGAAFLQERERQLAADCGRVDHVRALVKG
                     "
     gene            8064..9881
                     /locus_tag="M444_RS05090"
                     /old_locus_tag="M444_05075"
     CDS             8064..9881
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105668.1"
                     /locus_tag="M444_RS05090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05075"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_335338030.1"
                     /transl_table=11
                     /translation="MTRHGGSIIRFQLLGPLSIAHGPETVVLKPSKPTSLLAALLLHPN
                     SVVSTTYLLRAVWDEEPPATARAALQTCVLRLRRLFAKYGISATTIEAVPGGYRMRNDT
                     ETLDLVLFRTLTAGAGSATGPGEELYRLREALSLWHGQPLANVASRMLQQDAVPALEQE
                     RLRVLERVCDLELAAGNCHQVLVDLYEGARRHPVRERFTEQLIEALYRTGRQAEALAEY
                     RTVRDRLRDELGIDPGPGLRRLELAILRSEDLAPAPPVPRPAPARALTGSAVPALPPRG
                     APAHGRRPRREVPPVPAFAGRESDRRAIAERLTCADGPRLVVVSGAPGIGKSALARQTA
                     HETQHSFPGGVFVLALARPDGTPLTVEEAARLLPEAAADAGADTGADRQLIVLDDAAGA
                     WQVTPLLPAAGDASVIVTSRRALAAVVATHGGAVHRLDVLRPAEAYGLLAGLIGARRIA
                     AEPAAARELASVCGHFPLALRIAAGRLLTRPALSVADCAAWLAADPPARLALAEDARLS
                     VPEVFGQALDALAPDLREAFLRLGGPGADGDPSAGESESVLEQLVDCGLLEDGPPGPYR
                     VHDFLRVYARWHVRTHRTTAAAPAAAAPR"
     gene            10001..12226
                     /locus_tag="M444_RS05095"
                     /old_locus_tag="M444_05080"
     CDS             10001..12226
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Thiopeptide_F_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Heterocycloanthracin_C_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018515655.1"
                     /locus_tag="M444_RS05095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05080"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_037796977.1"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 3.8e-17,
                     bitscore: 60.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     6.5e-11, bitscore: 40.6, seeds: 5, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHASYEAVAATRPRIRRDVLFTETPDGVLFHNADGGFRLTAKSA
                     YRFATLIVPHLTGEHAVADLCRGLGEAQRTMVGELVRTLYERDFARPVTDPAPRADGQA
                     VLAPDVARRFAPQIAYADHYADDAEARFLRFRGTRVAVLGEDDVARWCASSLIRNGCAT
                     VGVTAGRVTSALGPEVAEAVGDGCPVELRTLAPADGRQPGWTELADYDLVVVTGGRTAP
                     ARLLPLLRAGIPAGAALLPAWSYGSDAVIGPLMTAGSAGCWACAALRLGGAAGRDTAAA
                     AELWSALALPGSPAASGPEPGRPLAAMIGNLLGYEVFRAASGALPAETAGQVIVQDMAS
                     LDVTAEPLLVHPRCPFCAPAEEEAALEAPAPVALTEAGTSGAPALPTLETAREADALVE
                     ELNRRSALVRPYTGVFTRYADEPLTQIPLKLSVVEFGVGHAGPRAVAAFDVHHVAGARM
                     RALDAAALVYAEHVVPARGVVARAEGAVAEASLTVASGLPGAAGAWQRAVSLVTKEPVL
                     VPAAAVRPFGPHNGDRLFERTRAGAGAGPSPADAAAAGLLSALAHDALLRAVRGAAAAP
                     VALTEGTPDAELAFLVRSAERLGITVELLDLGEAARSGVQVLLARAADRWAVGAALDRR
                     TATADALRDLLGAVQYERDAAASGAPADTGDPLLRDLDARTLTLSADAGDADGNPVAAD
                     WAGVLDRLRAAGRDAYVVPTGSADLASAGLHTARVLLTCAQEPGDDH"
     aSDomain        10031..10267
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_M444_RS05095_Thiopeptide_F_RRE.1"
                     /evalue="1.50E-19"
                     /identifier="RREFam004.1"
                     /label="M444_RS05095"
                     /locus_tag="M444_RS05095"
                     /protein_end="89"
                     /protein_start="10"
                     /score="60.7"
                     /tool="antismash"
                     /translation="ATRPRIRRDVLFTETPDGVLFHNADGGFRLTAKSAYRFATLIVPH
                     LTGEHAVADLCRGLGEAQRTMVGELVRTLYERDF"
     aSDomain        10031..10291
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_M444_RS05095_Heterocycloanthracin_C_R
                     RE.1"
                     /evalue="2.60E-13"
                     /identifier="RREFam011.1"
                     /label="M444_RS05095"
                     /locus_tag="M444_RS05095"
                     /protein_end="97"
                     /protein_start="10"
                     /score="40.6"
                     /tool="antismash"
                     /translation="ATRPRIRRDVLFTETPDGVLFHNADGGFRLTAKSAYRFATLIVPH
                     LTGEHAVADLCRGLGEAQRTMVGELVRTLYERDFARPVTDPA"
     gene            12216..14162
                     /locus_tag="M444_RS05100"
                     /old_locus_tag="M444_05085"
     CDS             12216..14162
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020610199.1"
                     /locus_tag="M444_RS05100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05085"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_078899640.1"
                     /sec_met_domain="TIGR03604 (E-value: 3.7e-90, bitscore:
                     301.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 2e-76, bitscore: 256.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDRIPAGRVGAGPEVVHALGPGAAARFTALLERALGALGGPRV
                     TLSALGTADAFARPAPGPGGSRAPVPVHLYGHQAVVGPPGGCARCLERRWQAVRSVALR
                     DALELGGDTLAAGAWPYAHAFAADALAALITAAGAPGTASPGGVFPQVRLLDLRTGSVR
                     RHPLVPDPECPGCAAPETDTAAGAALDLPPAPKYRPGVFRTRPVESYGIEVAAFANPLC
                     GALGPSLVQDVSSTTTSATIGCFSMRSGEYLRETFWGGHTDSLTRSGQVGVLEGLERYA
                     GMRARSRTTSVTGPLSRFGADAVDPREVGLYSEAFHRENPRVRPFDPDREIAWVWGWSL
                     RDRVPRLVPEILTYYHAPGLENRFVQESSNGCASGGSAAEAVYFALMEVVERDAFLLTW
                     YGRQPLPEIDPASSSRPATRAMVDRLAMYGYRARFFDTRITFPIPVVTAVAERFDGGTG
                     RMCFGAGAGLDPESALDSALCEIATDAVNLPGRTERDEARLRAMAADFSLVTALHDHPL
                     VYGVPEMGRHADFLLRAPGGGPTRTVAELEWPDRWGAAASDDVRTDLERCVSAVTAEGF
                     DVVVVDQTMPEQRKLGLHTVSVLVPGLLPIDFGWSRQRALGMPRMRTGLFTAGLRERAL
                     EPGDLNPAPHPFP"
     gene            14207..15799
                     /locus_tag="M444_RS05105"
                     /old_locus_tag="M444_05090"
     CDS             14207..15799
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268051.1"
                     /locus_tag="M444_RS05105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05090"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_047960443.1"
                     /sec_met_domain="PF00881 (E-value: 4.1e-12, bitscore: 45.1,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGYAHVYAHEIMHRGRVPMEPADFVPDWADRPRKAKFHPDAETLP
                     LPESPEPPEQAAGGVRGFTLPLLSGMLRDSYGLTGRRLAVQANTDLAALPHYTHANWSR
                     GTASGGGLYPVSVHWAAGPGGPLTPGLYHYAPHQHGLRRLLTGDVTGEVRSALGPGAGA
                     AAAATQYLVLGVKYWQNAFKYNSFSFHAVSMDVGALVQTWRLWAARYGLRIDPVLWFDE
                     ERLARLLGVAPEEEGIFAVVPLTWDGAPGAGQQGAAPAPAVTPAPETAPAVRHRDVERS
                     RRVLVFETLRRIHEATAGRAADRPAPDALDAAAAFPPRGGDPLPLPAPPAPPVTTRRAL
                     RERRSSFGRFDASRPLAAGPFAAALADCAATAYGTEAERPGGPPLTSLYAFVNHVEGIA
                     PGAYAYDPAAHTLRLRVPGPPGSFLQRNYFLSNYNLEQAGAVIVPTVRTTAVLDAVGDR
                     GYRLVGATIGAVAQTFYTTAAAFGLGAGVALGFDNISYREELGLTGTDEAPLLIMLLGH
                     DRPRPADFRHEIA"
     gene            15812..18595
                     /locus_tag="M444_RS05110"
                     /old_locus_tag="M444_05095"
     CDS             15812..18595
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890995.1"
                     /locus_tag="M444_RS05110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05095"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_037796979.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.2e-54, bitscore:
                     183.3, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTEWQAGDRFMLRVAGLPLSAVEALRATDTGRWAEEVLTAEAA
                     LRKGEQRLGDVLHEAVGATDPAPDGPGAAQRRALLRLRRQIHNGRPPARRDASTETAVE
                     AVAAMDEDAAEHLAGWLHRRGLLDKLLAEGPPLLAADLAGNRAALRELLADERLRHGLL
                     LASPVLEKQLDGYASAEGVPGGRARKAERSVLSYVYRTACKTSPFSTFTGVATGRFTGD
                     GAPGGAARVADVWSSHVRLNVVVLARLAELILADPVRRRDLPLRPASGWGHEEDRIRYV
                     RRSVTAGDDSAAVTFDAVKDRLFFLRRSGTLDRLLALFAGRPELRHRELTDWLAAEHAA
                     DPAECEAYVAALLQLGMVRVPCLDTEVHGGDPLRSFQRSLTSLERPWADRLAALLEAPA
                     AALAGYPEAGHAERAGLLRELRSGLHRAWEELGAPDAALPQTLLYEDVSAGHELPCAPP
                     DWTALRSVERILPAFDLTLAGRVTFEGFFTARYGSGGRCEDLLGLVHDFHEDFYDQYLS
                     FTARRKPFDERGEYVAEENWLGLPGIRALDAARRAFIGRMRRAWSAYEAAHGTHGADGA
                     DGTAADHIRLDEADLAEVAAELAPVIPDFAPRCHHLQFARDPADGTPLTVLNRSYGGLA
                     FPFSRFTHVYEEQGGPGPTDAPDAGFCAGLRDTARRVTPPGAVFAEVTGGPVTTNLNLH
                     GELTDYEIVCPGESGTLPPERRLHLDDLYAEHVPATGRVVLRSRRLGREVIPVYLGYLV
                     PLALPAIPRTLLLLSPSSMSPLDVWAGVPEGAALDRVTTRPRVVHGDVVLSRRSWTTTA
                     GALPVQGAREAGHFLDWQRWRRTHGLPEQVFATVSAGPSAAGAKPQYVDFASLLSLAAF
                     ETLLRDPAHRVVFREMLPGPDGPHVRSARGAHVAELAVETFTSTIRDQEGGTRCPR"
     gene            18583..19677
                     /locus_tag="M444_RS05115"
                     /old_locus_tag="M444_05100"
     CDS             18583..19677
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059797.1"
                     /locus_tag="M444_RS05115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05100"
                     /product="lantibiotic dehydratase C-terminal
                     domain-containing protein"
                     /protein_id="WP_037796980.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.3e-102,
                     bitscore: 342.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEMTPPAGARTDSPADTRGAWQALHIFYAANPQPLLTRCVRPLI
                     AELTADGLLAGHFFINYWLEGPHVRLRLRPVTPEAGPEVRRRAEEAVAAFLKARPALYE
                     VDSGFLNEFYNTLFDIEFPEGDRAAFMGPDGRMNLRPNNSYAREPYEPEFGKYGGPAGV
                     ELAEWHFARSSDLVMDALHRMNLHLRTVLLGTSAQLMMVMAGVFLPEREELAGYLDRYY
                     EFWHRAFPGTGFIGSEEYDRTYGQTAPGLGRRFAAVRGALAAGETGRLPAFLAGWAEHC
                     RELRERAEALAVAGDLVFRSWDGARDERVTDPALALPLLLSPYMHMTNNRLHVTIRDEA
                     YLAHLLGRVLRESEGVPEGAAVAP"
     gene            19674..20798
                     /locus_tag="M444_RS05120"
                     /old_locus_tag="M444_05105"
     CDS             19674..20798
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890993.1"
                     /locus_tag="M444_RS05120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05105"
                     /product="peptidase M50"
                     /protein_id="WP_047960444.1"
                     /transl_table=11
                     /translation="MTGPSPAPGPAGLLGHRPALRPDVLLSAPLLNGAATVHLVKDPVS
                     GASFEIGPKEFFLVSRLDGSRSLAEIGAAYAQAFGRRLGEGNWQQLLALLGTRRLLAGG
                     PPPATPAPPGGPLEGTLLRGRLRLVADADAATARLHRALRPLLHPVVLVALLLGCLAME
                     AALAVSFGELADGLGWLLRHPAPLLAVATLMWLSTALHEFAHGIAARHLGGTVGEIGLR
                     WRLPVAIMYCVVDNYRFLARRRHQVAVACAGAFANLLFLLPFFGWWAALPGGDPTRRAL
                     GALLLLGSAQALVNLLPLPPLDGYTMLGHGLRVTRLAPASSGYLRLRMRDRAAAAAYPA
                     RARRLYLAYGIGSALLVLLLAAGLTGAVWYAVTT"
     gene            20870..21898
                     /locus_tag="M444_RS05125"
                     /old_locus_tag="M444_05110"
     CDS             20870..21898
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890992.1"
                     /locus_tag="M444_RS05125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05110"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_047960445.1"
                     /transl_table=11
                     /translation="MTTDSTQPPDSPAISVQDVRKRYGDRQAVDGVSLDVRRGEFFGLL
                     GPNGAGKTTLIEIMEGLRQADSGTVRVLGHSPWPRDTALLPRMGVQTQASAFFVRQSAR
                     EHLVTVAGLYRRGPEAADRTLETVGLTEQRDVLVENLSGGQRQRLAIASALVHDPELIF
                     LDEPTAALDPQARRDLWEVLRALKSEGRTIVYTTHHLDEAEALCDRVAILVDGRTAALD
                     SPHRLVTAAGAPSRLLLPQGRLGVEEAAALPGVDRATVQGGSLVLETATPGKVLQAVDA
                     LTGLDGVMTRTATLEDVYLELTGAAHPGAAHPGAADPGAAETAAGHLGPQAGPHTQTEH
                     QA"
     gene            21895..22650
                     /locus_tag="M444_RS05130"
                     /old_locus_tag="M444_05115"
     CDS             21895..22650
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609025.1"
                     /locus_tag="M444_RS05130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05115"
                     /product="ABC transporter permease"
                     /protein_id="WP_037796981.1"
                     /transl_table=11
                     /translation="MSAYTALTAAGYRAQVRDKATLFFTFAFPLLFLVVFGLIFSGQDV
                     EETGRPYISYIAPGVMSWGVANAAVFGIAFTLMQWRRDDLLRLIRLTPTPLTTVLASRY
                     VLALAVGVVQAAVFVAVAMLPGFGLTLDGRWPLVLPALVLGITAFLAIGVIVGTYANTP
                     EAVAAIANCLMVPMAFLSGSFLPLDMMPSWLRQVSRVLPLRYLNDAATGALTGSGSLAT
                     IGTGCAVLFGFALLFGAIGLKTFRWSNRT"
     gene            22647..24587
                     /locus_tag="M444_RS05135"
                     /old_locus_tag="M444_05120"
     CDS             22647..24587
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018555846.1"
                     /locus_tag="M444_RS05135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05120"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_078899641.1"
                     /sec_met_domain="YcaO (E-value: 1.8e-72, bitscore: 243.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.3e-102, bitscore:
                     342.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPSVRPLAPDGTPLEAARRDLARALEPLGAVVVTLGVHDALGP
                     RAADPFAAVRPGATVHLTAREVLVGPWGGDGTAPACGQCLAMRRQRLRSRSERDALETG
                     GGPGTAAGPEWPRLSRYAYDAVSALHAAVHGGRAGAPGGAAAADRALPQVSRLDLETLR
                     IRTYPLLADPLCPDCGPRGTDAPRPFSPESRPKPDPGAQRLRAASSYPMPYAALANPVT
                     GVLGGGTWLNVTSPTTAPVAGSVFMRGYAGLTDVTWSGQANSFAASRDLAHLEGLERYA
                     GTHRRTGNSLLTASYAELGDRALDPAECGFYAPETYRDDPLVSPFDPERPIPWVYGHSL
                     RDDRPVLVPARLVHYSAGVAADNFVFECSNGCAIGSCLEEALLGALLELIERDAFLIAW
                     YGGLPLTEIDLATVPGTAVRTMADRAALQGYDVHAFDNRIDLAVPVVTGLAVRRDGGPG
                     LFSFGAGAALDPAAAVEAALSEVLTYIPHLPRQVEERRGELEEMAGDFSRVRHLKDHAQ
                     LYGLPAMAEHVRPYREPVAVRAMDEVYRSWTEHGRPRTGDLRDDLLCCVQELTQAGHDV
                     IVVDQTTPEQRRIGLRTVCAVVPGLLPIDFGWSRQRAPYLPRLRSAPRRAGLRATDLTE
                     AEVRMVPHPFP"
     gene            complement(24661..24834)
                     /locus_tag="M444_RS05140"
                     /old_locus_tag="M444_05125"
     CDS             complement(24661..24834)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268044.1"
                     /locus_tag="M444_RS05140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05125"
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_037796982.1"
                     /transl_table=11
                     /translation="MEKSPLASLAEEILELESETFEISDYSDASEVVLAGSTSCSSTST
                     CSSTTSTTSCSA"
     misc_feature    24896..24908
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            24998..26293
                     /locus_tag="M444_RS05145"
                     /old_locus_tag="M444_05130"
     CDS             24998..26293
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018845444.1"
                     /locus_tag="M444_RS05145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05130"
                     /product="amidohydrolase"
                     /protein_id="WP_037796983.1"
                     /transl_table=11
                     /translation="MTGPVPSSAAAPASPPVPAPLARLDAHLHALTAFYLELHRDPELS
                     GAERRTADRFAARLESAGFAVTRGIGGHGLAGVLRNGDGPTVLLRAELDALPVRETSGL
                     PYAADGEAAHACGHDLHLAAAAGTAALLAETPGAWRGTLVVVGQPAEETLEGARAMLAD
                     GLYRRCGRPDEVLAQHAAPLPAGMVAHGYGPVTAGSVTFRVVVHGRGGHAGAPHLAVDP
                     VVAAAHVVTRLQTVVAREAAPVEQVAVTVGSFRAGDRANVIPDRAELALTVRAVSEASL
                     ARAAEAVERIVRAECAAAACTREPEILRVSASPVTHPDPGVTASVREAHTAAFGAERVT
                     MWPPSLATEDFALFGDAGLEVHGERGIRLGYWMLGAAGPAAWSRAPGTTAAQKLAALPA
                     NHAPDFAPDVRTALPAGVRALTTAALARLGAP"
     misc_feature    26475..26488
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            26631..27050
                     /locus_tag="M444_RS05150"
                     /old_locus_tag="M444_05135"
     CDS             26631..27050
                     /GO_function="GO:0004867 - serine-type endopeptidase
                     inhibitor activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010468255.1"
                     /locus_tag="M444_RS05150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05135"
                     /product="SSI family serine proteinase inhibitor"
                     /protein_id="WP_229895449.1"
                     /transl_table=11
                     /translation="MRHRIAAVSAAALVAIAGSIGIAEAQPASLYAPSAVVLAVAQGEN
                     AATVVRATTVSCAPTAQGTHPDPRGACAALNAAAGSLDALLAAPDTNRACPMHYDPVTV
                     TADGVWKGSRIAWKHTFSNSCAMSATLNGNAAFAF"
     gene            27206..27937
                     /locus_tag="M444_RS05155"
                     /old_locus_tag="M444_05140"
     CDS             27206..27937
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262388.1"
                     /locus_tag="M444_RS05155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05140"
                     /product="hypothetical protein"
                     /protein_id="WP_037796984.1"
                     /transl_table=11
                     /translation="MNAAGEGPQLPDAVSVANAKTTLLQLLARAGVFTGDTEELIGLVE
                     AGALARAYEEITARAGSAPGDKGEPYESGWLDGARDVVDELGAIATRAGRRSAGSDAPD
                     ESPEERPRVRRMELERAQVAVTPLYLSFTSVSDFDPEVTSEVLTAILGTMSSRQRAQYA
                     GRLTEFSASHRARLERLYTEYGPGSPIAIHGRYSVVHSPTSLAVLERLATAPSALREEW
                     DAAELPPAWLDGLTTAWNASA"
     gene            complement(27990..29651)
                     /locus_tag="M444_RS43865"
                     /old_locus_tag="M444_05145"
     CDS             complement(27990..29651)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1-42). E-value:
                     0.00096. Score: 11.9. Matches aSDomain:
                     nrpspksdomains_M444_RS43865_PKS_Docking_Cterm.1"
                     /NRPS_PKS="Domain: Abhydrolase_1 (102-254). E-value:
                     5.1e-16. Score: 50.9. Matches aSDomain:
                     nrpspksdomains_M444_RS43865_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577623.1"
                     /locus_tag="M444_RS43865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05145"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_078899805.1"
                     /sec_met_domain="PF00561 (E-value: 2.3e-18, bitscore: 65.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTTGTAIPLRAAAGAVAAALLALLSAAGPASAGGPGGGDGGDGG
                     RGVVLRWKPCTRNAQAGFECAVAKVPLDHAEPSGRTIDLAVIRHRAAAAGRRAAGSLFF
                     NPGGPGGPGTVGLPELYRKFPAELRDRFDIVSWDPRGVGESTAVRCFDTAKEAAAWHAK
                     VPPFPVGAGQRQAFVTAYAELAQRCERRDPELLRHISTADTARDLDLLRRAVGEERLRY
                     WGVSYGTLLGATYANLFPDRVGRLVVDGNVDPRAWTDGGAGAEPARSTFLRLGSDLGSA
                     DTLGQFLDLCGRAPMTGCAFSAGSPAATRAKYATLLARLAERPVGRWTYARAVSEVRGG
                     LYTVHPGWSGTAATLESLWQGVAPGESPAVAAPARYPGFEQSLAVLCAESPNPAPSGRY
                     PALEERAVREAGPLARWWVWANEPCAAWPARAADPYTGPWNRPTAHPVLVVNSVHDPST
                     PYRAGEAMARELGRARLLTLDGYGHTALGNPSACVGRHVVRYVVTGALPARGARCAQDT
                     PPFVNPGEPSVAAAAVTPPGGLLRTWPPAWLPRGAG"
     aSDomain        complement(28890..29345)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M444_RS43865_Abhydrolase_1.1"
                     /evalue="5.10E-16"
                     /label="M444_RS43865_Abhydrolase_1.1"
                     /locus_tag="M444_RS43865"
                     /protein_end="254"
                     /protein_start="102"
                     /score="50.9"
                     /tool="antismash"
                     /translation="FFNPGGPGGPGTVGLPELYRKFPAELRDRFDIVSWDPRGVGESTA
                     VRCFDTAKEAAAWHAKVPPFPVGAGQRQAFVTAYAELAQRCERRDPELLRHISTADTAR
                     DLDLLRRAVGEERLRYWGVSYGTLLGATYANLFPDRVGRLVVDGNVDP"
     aSDomain        complement(29526..29648)
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M444_RS43865_PKS_Docking_Cterm.1
                     "
                     /evalue="9.60E-04"
                     /label="M444_RS43865_PKS_Docking_Cterm.1"
                     /locus_tag="M444_RS43865"
                     /protein_end="42"
                     /protein_start="1"
                     /score="11.9"
                     /tool="antismash"
                     /translation="RTTGTAIPLRAAAGAVAAALLALLSAAGPASAGGPGGGDGG"
     misc_feature    29790..29804
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     misc_feature    complement(29836..29846)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            29841..30395
                     /locus_tag="M444_RS05165"
                     /old_locus_tag="M444_05150"
     CDS             29841..30395
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606489.1"
                     /locus_tag="M444_RS05165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05150"
                     /product="hemerythrin domain-containing protein"
                     /protein_id="WP_037796985.1"
                     /transl_table=11
                     /translation="MGHGADVIEELMCDHREVDDLFSAIERTAPALDRQTLAEQLTIEL
                     VRHAVAEEEHLYPAIREHFPDGELIADKELADHARVERMLKDLEGVDGAGLEFDRRIAE
                     LRAEVTAHVWDEEQNLFPRLRQGCSPEDLHRLGDKVRRAKKFAPTRPHPGAPGTPPAGR
                     LPAPVTGLVDRARDFVSGRGR"
     gene            30889..32343
                     /locus_tag="M444_RS05170"
                     /old_locus_tag="M444_05155"
     CDS             30889..32343
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="M444_RS05170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05155"
                     /product="cytochrome P450"
                     /protein_id="WP_037795043.1"
                     /sec_met_domain="p450 (E-value: 7.5e-50, bitscore: 168.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALVSVAVAGLLVLAVRRRLTEFRSRRHLPGPKPSFFLGNMSDLL
                     LHGHGGRHESLQALHDEYGPLVCFHAAWGSAPFVSLSYVSPNLLRKELDSHRRADRTVL
                     SRSLMGMAGGELHQTHRQVIAPSMAFRGVSERGSVLKDVSDRYVDKWKHVDEGYEGLQS
                     DLRDWSVNCLSAFLFGDDWDVGADLHAYHRALSAIEEEVSFRAFHPFFVRWVFPRRRRR
                     VRAAYHRVAAELGEVVTRREQRIPAACPAHGATGAAAATGAAGGDLLDRVTRAPWSAED
                     RVEELMSLILGGADPMSYVLSQALVMLSLDPHVQEKARKTIEASSSCAQEGDPGPDPYV
                     RNIVYETLRMFPPVPFSAKFSDERAVVEQGMSIPPGTVIMWMKNAVGKNPEIFREAERF
                     NPDRFDPERFPADGEKRNDTISSFLPFGAGPRHCVGNRLAEQQCIVLLTEILKNFHVVP
                     LRHIKVQFHSTISVVPSAVPVRLVPR"
     gene            32355..32894
                     /locus_tag="M444_RS05175"
                     /old_locus_tag="M444_05160"
     CDS             32355..32894
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019498.4"
                     /locus_tag="M444_RS05175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05160"
                     /product="quercetin 2,3-dioxygenase"
                     /protein_id="WP_008743463.1"
                     /transl_table=11
                     /translation="MTEGGRTAPIALGRDEGEALWFLDFLAKVKGSSAEMNGASSVVEF
                     LGRSGSGSPLHVHHHDDEWWYVLDGEMTFWVAGREFPATPGSFVYGPRHAPHTFLVTSE
                     EARFLHVTEPGGFDGFLRELARPARSLEIPSDVNALPDLEQILAVAAPYGIEVLGPPGI
                     PAALPDPGTQKEGRTP"
     misc_feature    32361..32370
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            32891..34111
                     /gene="txtE"
                     /locus_tag="M444_RS05180"
                     /old_locus_tag="M444_05165"
     CDS             32891..34111
                     /codon_start=1
                     /gene="txtE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010352784.1"
                     /locus_tag="M444_RS05180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_05165"
                     /product="4-nitrotryptophan synthase"
                     /protein_id="WP_008743464.1"
                     /sec_met_domain="p450 (E-value: 2.3e-19, bitscore: 68.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKPSPLSDPGIVADPYPVYARLARREPVHWDEGLNAWAVMKYAD
                     CAAALKDPRLKAERMEEVLEVKFPGEPLPPDDIYHRFTKNVMMYTDPPLHDALRRSTQS
                     GFTRAAHEHYGQVIERVAADLVASVPGGTREIDAVAAFAAELPVRSAVSAFGVPEEDLA
                     FVIPCVETLMTYWSGPQDQPVELGRLLELLADLHTYALELIEGERGKVLPDTVIARLAA
                     AQDGLTETTPEQTVHQLVLLFIALFAPTTPGSLSSGMLSFARNPDQIARFLAEPACVEN
                     TANEVFRHNASNQFTWRVATTDLDVGGVRIGKGQSLALFLGAANRDSEVFERPDVFDLG
                     RPNSAKHLSFGQGVHACLGRQIAGLQLKWFFVALLRRFPAVRPAGEPVWNQNLEFRSLR
                     SLPLSLR"
     misc_feature    34091..34093
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(34138..34153)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
ORIGIN
        1 acggcggtga cgaagagcat ccagtggagc ggctcgctcg ccccggcggc ctcctggacg
       61 gtcaggctcg tgggcaccag gtagggccgc tgggcgagtc cccaggcggc gaccagcagc
      121 gccacggtgg ccaccgagga gtaccgagcc cacccggagg cggggccgga gaccagccag
      181 gtggtgagca ccagggccgc gacggcggcg aggagggcgg ccagtccggc gccgtgggtg
      241 agcccgtggt ggacgtacgc ggcctgcggg tcggtcagcg tcacaccgat cacgccgacc
      301 acgagcaggg cgaagccggc gatccgggcc cggaggcgga agtagccgat caggtcggtg
      361 gccccgaagc gccgggcgtc cacggagagg aagaccgccc cgaggaaggc ggtggcggcg
      421 acggccacca ggccggccat gaccgaggtg gtgttggccc aggcgtgtgc cgaggcgacg
      481 gtgcccggtg cgacgcgccc ggaggccacg cctccgatga ccgcgcccag gaagaacggg
      541 gtgagcaggg aggagacggc gaaggcggcg ccgtagatcc ggcggccggc gaggttgcgg
      601 gtgggcttgc gcagggcgaa accggcgccg cgcaggacca tgccgacggc ggcgagcgcc
      661 agggggagcc acagggcggt gaacaccgtc tggaagaact ccgggaatcc ggtccacatc
      721 agcaccagta cgaagatcag ccagacgttg ttgacctccc agaccggtgc catggcgtgg
      781 tcgatcagcc agcgcgggcg cttgccccgt gccgcgccgc cggcgcacag gtcccagaac
      841 ccggcgccgt agtcgactcc gccgccgcac gcgtaggcgg cgatcacgag cagcaggatc
      901 caggcgacga cgttcgcggt cactgctcgc tcccgggtgc tcggtggtca ccgggggcgg
      961 cgccggccgg ttcgggacgc gggccgtacg gggtgtccgc ctccgggtcg tcggcgggcg
     1021 ccccggccgg tccggggccg gacgcggcgt cggcgagccg ccagcggccg ctcatcttca
     1081 gcaccacgcc gaggagcgag ccgaagacca gcaggtagac cacgacgacg agaccgaaca
     1141 cggcccacag ggcggaggcg gaggtgggcg tcaccgcctc ggacacccgc atgttctggt
     1201 agacgatcca gggctggcgg cccacctcgg tgctgatcca gccgcattcc acggtcacca
     1261 cgctggccac gccggacagg gcggcgcagc ggaagaacca gggggacttc ggcaggtcgc
     1321 ggtggcgcca ccagcaccag gcgtaccaga gggcgagcag gatcagggcg gtgccgacga
     1381 gtgccatgat gtcgaaggcc cagtgcgcga tggtcgcctg ggtggcggtg gggcggtccg
     1441 aggcgggcac cgagctcagg ccggtgacct tcgtgtcggg actcttcccg gccaggatgg
     1501 agtcgagctg ggggatcttg atgccgccct tgacggtgcc gtcctcctgg agccggccga
     1561 acaggtactc gggaacgtgc gtgtcggtgt cccagaccag ttcgagggcg gcgaatttga
     1621 tgggctgctt gaggaagacc tgcctcgcga tgttgtcgcc gagcacgaac tgcacggggg
     1681 tgaggatcgc ggcgacggtg aacggcacgg tgaaaccgag gcggtggtag cggtcgcggc
     1741 ggccccggag ccagccgacc gcgtagaccc cggccaccac gtagccggcg gtgatgaaca
     1801 tggcgacgac gaagtgccag tactgcgggc cgaacatcgg cgtgaagatc gcctgccgga
     1861 cggtgacgtc caccgggcgg ccgttgccgt cgagggtgaa gccgcgcggg gtgttcatcc
     1921 acgagttggc ggcgatgatg ccgaaggcgc ccatcagggc cgccagcggc agcggtacgc
     1981 cgagccagaa gtgcgtcttc ggcggcagcc ggcgccagcc gtagaggtag atggcgatca
     2041 ggatcgcctc aaggaagaag gcccaggcct cgacgccgaa gccgaggccg aagacatcgc
     2101 cccagcggcc catcatgccg ggccagagca ggccgaactc gaaggagagc acggtgcccg
     2161 tgatgatgcc gacggcgaac tgcacggcca tcacggcgga ccagcggcgg gccagcagca
     2221 gcgcgacggg gtccgacttc cgcaggcccc ggtggtgcat gaccagggtg atgaacggca
     2281 acgccacccc cagcggcacc agggtgatgt gcatggccag ggtgaacgcc atcaattccc
     2341 gcgcgggcag cagttgcgcg ggggcgtccg ccaggaggtg tactgggatc atcaagcggt
     2401 cctcggtgac tcgtgagggc ggggggtcag cctccggtcg cgaagccggg gaagagggtc
     2461 atcccgccgt cgacgtagag ggtggtcccg acgacgtaat ccatcaggtc ggaggccagg
     2521 acggtcaccg cgttcgcgat gtcctcgggg tccccgaccc ggcggtaggg gatcagctgg
     2581 agcagggcct tctcagcctc gggggtgtcc caggcgtcct tgttgatggg ggtgcggatg
     2641 gctccgggcg cgacggcgtt cacccggatg ccctgcgggg cgagttcctg ggccagcgtc
     2701 tgcatcatca tcaggactcc gcccttggac gaggcgtagt tcacgtggcc cgcccagggg
     2761 atgatctggt ggacagagct catgcagacg atcttcccgg ccgagcggga cacctccggc
     2821 acgacgccgc ggcgcaggaa ctccttcgtc gcctcccggg cgcacaggaa ctggcccgtg
     2881 aggttgacgt ccagcacctt ctgccactgg gcgaccgtca tctcggtgac ggccgcgtcc
     2941 cgctgcagtc cggcgttggc caccatgatg tcgatcgtcc cgaactcctc gaccatccgg
     3001 tcgaccatcg cgacgacctg gtcctcccgg gagacgtccg cctcgtgcgc gtaggcccgc
     3061 accccgtggg acttgatctc ctcgacgacc gcctcggcct cctgcgctcc ggcgacgtag
     3121 ttcacgacca cgtcggctcc cgcgcggccc agcccgatcg cggtcgcctt gccaatgccc
     3181 gagttggccc ccgtcaccag ggccttctgc cccttgagaa tccgcggcgt ctccctgagc
     3241 gtctggtccc cggtcgacat cactcgtctc tcccatcgtt ggccccaccc accggcaccg
     3301 gcagaccacg gtcgcccgcg cgcaagcggg cggcgccggg cggctcgcgc cgctcggccg
     3361 atcggggcaa ccacacccct ccgacggcgt aaggagcggc cggagggagc cggtcgccgg
     3421 gatgatctcc tgaccggacc gtccggctcg cgggccaccc gggagggcgc tgtggagaca
     3481 tccggaccgg cacggccggc cccgcccgtc gtggtggtca tgggggtgtc cggctcgggc
     3541 aagagcaccg tgggccgcct cctcgccgcc cgccgcgggg tgcccttcgt ggagggcgac
     3601 gacttccacc cggcggcgaa catcgccagg atgcgcgccg ggcaccccct cgacgacgcg
     3661 gcccgcgagc cctggctgac cgcgctgacg gaggcggtcc gcgaggtcgt gcgtgccggc
     3721 gagggcgccg tcgtctcctg ctcggccctc aagcgcgcct accgggaccg ccttcgcgag
     3781 gccgccccgg cggtgtggtt cctgcacctg acgctggacc gggcggtggc gcacgcccga
     3841 gtcgccgggc gggccgggca cttcatgccg gcccggctcc tggagtccca gtacgaggtc
     3901 ctggaaccgc tgggcgccga cgaggacggc ctcaccctcg acgccggcgc gggcaccgac
     3961 tccgtactgc gccgggccgg ggaggccctc gccggcttcg aggcccggtc ggtttgaccg
     4021 acgccgccag gggcaggcgc gcggcagagg ctgaagaggc ccggatggag aaacaccatg
     4081 tcgaccagca tgctcatagc cgtgatcgtg atcgcggccg tcctggtgat cgcactcgcc
     4141 gtggggctgt ggaccaggtc ccgccgacgg cacctgcgca gccggttcgg tcccgagtac
     4201 gaccggacgg tggaggccga aggcggccgc aaggccgcgg agcgggagct gcgctcccgc
     4261 gaggcgcgcc acgacgcgct tgagatcaag gaactgccgc cggagcggcg caagcagtac
     4321 accgaggagt ggagcggcgt ccaggaggcg ttcgtggacc gcccggagcg ttccgtcggc
     4381 gaggccgacg agctggtcac ccggctgatg cgcgagcgcg gctatcccac ggaggactac
     4441 agcgggcagc tgcgcgacct gtcggtggaa cacggacgca cggtggagca ctaccgcgcc
     4501 gcgcacgacg tcaaggtgcg cagcggcgcg ggacagacga cgacggagga actccgcggc
     4561 gcgatggtgc actaccgcgc gctgttcgag gaattgctga gtgatcagag gagccggtga
     4621 catgcgcgac cacggagagc gggacgcccg ggccgacgag gcggggctga cgaccgagga
     4681 catcgcccac ccccaggcgg gggcgcccgc ggcgaccacc cgcgaggacg agcggcagca
     4741 ggtgcccgtg tacccgggtg aggccaccgc ggacccgcgg gacgccgccg agggcatacg
     4801 ggagacggac ccgggcacgc gggaggcgga tgacgggacc ggggctccgg ggcgggcacc
     4861 gacggagcag tgggacgggg agccggggcg ggccacgacg gagcgcgggg ccgtggacgc
     4921 cccggcggcg gatgaggaac cgctgctcgg cgccccggac gcggagggct accgcaaggc
     4981 ctggagcgag atccagggca ggttcgtgga cgacccgcag gaggccgtca ggtccgccga
     5041 cgccctcgtg gccgaggtga tgcagaccct ggcccggacc ttctccgccc gcaagcaggg
     5101 cctggaagga cagtggggcc agggcgggca ggtcgccacg gaggagctgc ggctggcgct
     5161 ccagcagtac cgctccttct tcaaccgcct gctgaacacc taggcggcca ccgggcccgg
     5221 tgctcggtgt cccgggcgtg tggcgggcgc aaccctgggc agaagcccgg cagagagaca
     5281 gaccgccgga gaagggatcc gttccatgct gatggcccac cccgcactgc tgcccgccgc
     5341 cgtccgtgag tacgagacgc tgagcctcct gaacgccctc gaagggagtc cgaggacggt
     5401 ccgtcgcatc gaggaactct cggccctgct gtgcacggcg accggtacgg gcagcgcgga
     5461 ggcggccgtc gtcgccgccc gctaccggct ccccggtgcg gggaccttcg acgattcggt
     5521 gatacccgcc cgctgagggt gcgtgcgggt gcgtgccggg ggcgcccacg cgagactgct
     5581 cgcgtgggcg cccccgtgcg cgtcccgctc cccggacgag gaggcacatg aaccgggccg
     5641 cgctgttcga cgtggacgga accctggtcg acaccaatca cctgcacgtc acgtcctggt
     5701 gggaggcgct gcgccaggcg gggcacgacg taccgatgca cgccatccac cgtgcgctcg
     5761 gcctgccggg cgaggacctg ctctcccacc tcctcggcga ggagcgggac accggcgggg
     5821 acggggcgct gagcgccgcc cacgacaccc tgtacgcgac gtacttcgag cgcctgcccc
     5881 ggctgcgctc ggcggacgag ctgctgcgca cgctgagccg ccggggctgg cgcgtcgtcc
     5941 tggtcacctc ggccggaggc ggcgagctcg acgcgttgcg gagggcgatc ggcgcggacg
     6001 acgccctcac cgccaccgcc agcgccgatg acgtggaacg gggcaagccc gccccggacc
     6061 ccgtccgcca cgcgctggag ctggcggacg cgtccgcgca cggctccgtg ttcgtcggcg
     6121 acagcgtgtg ggacatgaag gccgcgaccc gggcgggggt gcggcccgtg ggcttcctca
     6181 gcggcggcat tccccgtcac gacctcgaag cggcgggcgc cggcccggtc taccgggatc
     6241 ccgcggacct gctcgaacac ctcgacgcga gtcccttcgg cgttgcgggc tgagccgggc
     6301 gccgacgcgt ccgcgggttc ccggcgagga tgggcgcatg accgacacgt tcaccacacg
     6361 cacgctcgat gtgacgacgg gctccgggga gaccgtccac gacctgacct cggcctgcgc
     6421 ggagttcctg agtgaggccg cccgtggccg ggacgggctg ctcaacgtct tcaccccgca
     6481 cgcgacggcc gggctggccg tcatcgagac gggcgccggc agtgacgacg acctgctgga
     6541 cgcgctgcgc acgctgctgc ccgccgacga ccgctggcgg caccggcacg gttcacccgg
     6601 ccacggccgc gaccacgtac tgcccgcgtt cgtgccgccg cacgccaccc ttccggtggt
     6661 acggggcgag ctggctctcg gaacctggca gtcggtggtg ctggtggaca ccaaccggga
     6721 caatcccgag cgcacggtac ggctgtcctt cctgggctga gcggtccccc gcgacccgcc
     6781 cgatgccggg cgtttggatt cctccgcagc gagcacccgg cgattgacgg gagtcacgaa
     6841 caatcggggc tcggcgggag aaatcgagga gacgtcgtgg gaatcatcgc gtggatcgtc
     6901 atcggactgc tcgcgggaat cgtcgcaaag gccctgctgc ccggcagaga tcccggcggc
     6961 atcatcatca ccatcctgat cggcatagcg ggcgcgctcc tcgggggctg gctcggcaag
     7021 gtgcttttcg gtgtcgattc catcgacggg ttcttcgagg tgtcaacatg ggtcgccgcg
     7081 atcgtcggtt cgatgatcct gctgctcgcc taccggatgg tctccggtgg aggccggcgg
     7141 cgctgagccc cccttcggta accggaacaa acacgagcag gagcaggagc ggaccatgac
     7201 cgtgcagcac gacgtcgtcg cggtgatcct caaggaccac cgcaccatgg aggacctcct
     7261 ccgccggatg cggagcgtgg aatccgaccg cgcgaaggca ctcgaacagt tttcggccct
     7321 gctcatcgcc cacggcgagg ccgaggaggc caaggtgtac ggcgccctga agcggttcaa
     7381 ggacgtggac aacgaagagg tggagcacgg ggccgaggag cacgccgagg gcaacgcggc
     7441 gcttctggca ctgctggagg tgtccgaggt cggctccgac aggtgggacg agcggctgga
     7501 agacctggtg aaggccgtgt cgcaccacat cgacgaggag gaacggacca tcctcaacgg
     7561 cgcccgggag aacgtgcccg acgagcgccg cgccgagctg ggcgccgcct tcctccagga
     7621 gcgcgagcgg caactggcgg cggactgcgg ccgcgtcgac cacgtccgcg ccctcgtgaa
     7681 gggctgacgg ccggtcgtca ccccggtcgg ggggcgacga ccggccagat cagtggcggg
     7741 atatgcacct taactggatc accacatcgt gcttggatgg cgccgccacc gtaattcgtt
     7801 tagcactgaa cggttttgac gaaccgacgg taactcctcg aagcgcccag gttacggaga
     7861 agggagaaac agccggcggg cgccgaacaa gtcacccttt ggctcgactt ccacaagatc
     7921 cgttatgtag tgttccagtc attcaccgcc caacgggggg cgagcagcga ctgcaggcct
     7981 ggtccggact atttccggcg tgtgacgggc cccgcggaac cggcagacca ccgcccccgc
     8041 cacgctccct atagggggaa tgcgtgaccc gacacggggg atcaatcatc cggttccagc
     8101 ttctggggcc tttgagcatc gcgcacgggc ccgaaaccgt cgtactcaaa ccgtccaagc
     8161 cgaccagtct tctcgccgcg ctcctgctgc atcccaactc cgtcgtgtcg accacttatc
     8221 tgctgcgcgc cgtgtgggac gaggaaccgc ccgccaccgc ccgcgccgca ctgcaaacct
     8281 gcgtgctccg gttgcgccgg ctgttcgcca agtacggcat atccgcgacc accatcgagg
     8341 ccgtgccggg cggttaccgg atgcgcaacg acaccgagac cctcgacctc gtgctcttcc
     8401 gcacgctcac ggccggcgcg ggatccgcga ccggcccggg agaggagctc taccggctca
     8461 gggaggccct gtccctctgg cacgggcagc ccctggccaa cgtggcctcg cgcatgctcc
     8521 agcaggatgc cgtccccgct ctcgaacagg agcggctacg ggtcctggag agggtctgcg
     8581 atctggaact cgccgccggc aactgccatc aggtcctggt cgacctctac gagggcgccc
     8641 gccgccaccc ggtgcgcgaa cggttcaccg agcagctcat cgaggccctc taccgcaccg
     8701 gacggcaggc cgaggcgctc gccgagtacc gcaccgtacg cgaccggctc cgcgacgagc
     8761 tgggcatcga cccgggcccg ggactgcgcc gtctggagct cgccatcctg cgctccgagg
     8821 acctggcgcc cgccccgccg gtgccccggc cggcgcccgc ccgggcgctg accgggtccg
     8881 cggtccccgc actgccgccg cgcggcgcgc ccgcccacgg ccgccggccg aggcgggagg
     8941 taccgcccgt ccccgccttc gccgggcgcg agagcgaccg aagagccatc gccgagcggc
     9001 tcacctgcgc cgacgggccg cggctggtcg tcgtctcggg cgcaccgggc atcggaaagt
     9061 cggcgctggc ccgtcagacg gcccacgaga cacagcactc cttccccggc ggggtgttcg
     9121 tactcgcgct ggcccggccc gacggaacac cgctgaccgt cgaggaggcg gcccggctgc
     9181 tgcccgaagc cgctgcggac gccggcgcgg ataccggcgc cgaccgacag ctgatcgtcc
     9241 tggacgacgc ggccggcgcc tggcaggtga ccccgctgct tcccgcggcg ggagacgcct
     9301 cggtcatcgt gaccagcagg cgcgccctgg ccgcggtcgt cgccacgcac ggcggcgcgg
     9361 tgcaccggct cgacgtgctg cggcccgccg aggcgtacgg gctgctcgcc gggctcatcg
     9421 gcgcccggcg gatcgccgcc gagcccgcgg ccgcccggga actggcctcc gtctgcggtc
     9481 acttcccgct cgccctgcgg atcgccgccg gccggctgct gacccggccc gccctgtcgg
     9541 tcgcggactg cgcggcatgg ctcgcggcgg atccccccgc ccggctggcc ctcgcggagg
     9601 acgcccggct ctcggtgccg gaggtgttcg ggcaggcgct cgacgcgctc gccccggacc
     9661 tgcgggaggc gttcctccgg ctgggcgggc ccggcgcgga cggcgatccg tcggccgggg
     9721 agagcgagag cgtgctcgaa cagctcgtgg actgcgggct gttggaggac gggccgcccg
     9781 gcccgtaccg cgtccacgac ttcctccgcg tctacgcgcg ttggcacgtc cgcacgcacc
     9841 ggacgaccgc ggcggccccg gcggcggccg caccgcgctg acctcccgcc cggtccgtcg
     9901 caccacccct ccgcccacac cgctccccca ctcaccgctc ccctctcccc cctacgctcc
     9961 cccctcccga tcccgcccag accgcaccca ggggtgtccc atggctcacg ccagctacga
    10021 agccgttgcc gcgacccgtc cccggatccg ccgcgacgtg ctgttcaccg agacgccgga
    10081 cggcgtgctg ttccacaacg cggacggcgg cttccgcctg acggccaagt ccgcctaccg
    10141 cttcgcgacg ctgatcgtgc cccacctcac cggcgagcac gcggtcgccg acctgtgccg
    10201 gggcctcggc gaggcacagc ggacgatggt cggcgaactc gtccggaccc tgtacgagcg
    10261 ggacttcgcc cggcccgtca ccgaccccgc cccgcgcgcc gacggacagg cggtgctcgc
    10321 tcccgacgtg gcccgccggt tcgccccgca gatcgcgtac gccgaccact acgccgacga
    10381 cgccgaggcc cggttcctgc gcttccgcgg cacccgcgtc gccgtcctcg gcgaggacga
    10441 tgtggcccgc tggtgcgcgt cgagcctgat acgcaacggc tgcgcgaccg tcggcgtgac
    10501 ggcgggccgg gtcacctcgg cgctcggccc ggaggtcgcc gaggccgtcg gcgacggctg
    10561 ccccgtcgag ctccgcacgc tggcgccggc cgacgggcgg cagcccggct ggaccgaact
    10621 ggccgattac gacctcgtcg tcgtcacggg cggccggacc gcgcccgccc ggctgctgcc
    10681 gctgctgcgc gccgggatcc cggccggcgc cgccctgctg cccgcctggt cgtacggctc
    10741 cgacgccgtg atcggccccc tgatgacggc cggcagcgcc ggctgctggg cctgcgccgc
    10801 gctccggctc ggcggcgccg ccggccgtga caccgcggcc gccgccgaac tgtggagcgc
    10861 gctggcgctg cccgggagcc ccgccgcgtc cggccccgag ccgggccggc cgctggccgc
    10921 gatgatcggc aacctcctgg ggtacgaggt cttccgcgcc gcctcgggag cactgcccgc
    10981 cgagaccgcg ggccaggtga tcgtccagga catggcctcg ctggacgtca ccgcggaacc
    11041 gctcctcgtc cacccgcggt gcccgttctg cgccccggcc gaggaggagg cggcgctgga
    11101 ggccccggcg cccgtggccc tcaccgaggc gggcacctcc ggggcgcccg ccctgccgac
    11161 cctggagacc gcgcgcgagg cggacgcgct ggtggaggag ctgaaccggc gctccgcgct
    11221 ggtccgtccg tacaccggcg tcttcacgcg ctacgcggac gagccgctca cccagatccc
    11281 gctgaagctg agcgtggtcg agttcggcgt cggccacgcg ggtccccgcg cggtcgcggc
    11341 cttcgacgtc caccacgtcg ccggggcgcg gatgcgggcg ctggacgccg cggccctcgt
    11401 gtacgccgag cacgtcgtcc cggcgcgcgg tgtcgtggca cgcgccgagg gggcggtcgc
    11461 ggaggcctcg ctgaccgtcg cctccggtct gccgggcgcg gccggggcct ggcagcgggc
    11521 cgtctcgctg gtcacgaagg aacccgtgct ggttccggcg gcggcggtgc gcccgttcgg
    11581 gccgcacaac ggcgaccggc tcttcgagcg cacccgcgcc ggcgccggag ccggcccttc
    11641 gcccgccgac gcggcggcgg ccggcctgct gtcggcgctg gcccacgacg cgctgctgcg
    11701 tgcggtgcgc ggggcggcgg ccgcgccggt cgcgctgacg gaggggacgc cggacgccga
    11761 actcgccttc ctcgtacggt cggcggagcg cctcgggatc accgtcgagc tgctcgacct
    11821 cggcgaggcc gctcggtccg gggtccaggt gctgctcgcc cgggcggcgg accgctgggc
    11881 cgtgggcgcc gccctggacc ggcggacggc gacggccgac gccctgcggg acctgctggg
    11941 cgccgtgcag tacgagcgcg acgccgcggc ttccggggct cccgccgaca ccggtgatcc
    12001 gctgctgcgg gacctcgacg cccgcacgct caccctgtcc gccgacgccg gtgacgccga
    12061 tgggaacccg gtcgccgccg actgggccgg ggtgctggac cggttgcgcg cggcgggccg
    12121 tgacgcctac gtcgtcccca ccggctccgc cgacctggcc tccgccggac tgcacaccgc
    12181 cagagtgctc ctcacctgcg cccaggagcc gggcgatgac cactgaccgg atccccgccg
    12241 gccgggtcgg ggccggcccc gaggtcgtcc acgcgctcgg cccgggcgcg gcggcccgct
    12301 tcaccgcgct gctggagcgt gccctcggcg cgctcggcgg gccgagggtg acgctgtcgg
    12361 cgctggggac cgcggacgcc ttcgcgcgcc ccgcccccgg acccggtggg agccgggccc
    12421 ccgtgcccgt gcacctgtac ggccaccagg cggtcgtggg gccgcccggc ggctgtgcgc
    12481 ggtgtctgga gcgccgctgg caggccgtgc ggtccgtcgc gctccgggac gccctggagc
    12541 tgggcggcga caccctggcc gccggtgcct ggccgtacgc gcacgccttc gccgccgatg
    12601 cgctggccgc gctgatcacc gccgccgggg cgcccggcac cgcctccccc gggggcgtct
    12661 tcccccaggt gcggctcctg gacctgcgga ccggctccgt acgccgccat ccgctggttc
    12721 ccgaccccga gtgcccgggg tgcgccgcgc cggagacgga caccgcggcg ggggccgccc
    12781 tggacctgcc gcccgcgccc aagtaccggc ccggtgtctt ccgtacccgc cccgtcgagt
    12841 cgtacgggat cgaggtggcg gccttcgcca acccgctgtg cggggcgctg ggtccctccc
    12901 tcgtccagga cgtctcctcg accaccacct ccgccaccat cggctgtttc tcgatgcgtt
    12961 cgggcgagta cctgcgcgag acgttctggg gcggtcacac ggactccctc acccgcagcg
    13021 ggcaggtggg ggtcctggag gggctggagc gctacgccgg gatgcgggcg cggtcgcgga
    13081 ccacgagcgt caccggtccg ctgtcgcggt tcggcgccga tgccgtcgac ccgcgggagg
    13141 tgggcctgta cagcgaggcc ttccaccggg agaacccgcg cgtgcgcccc ttcgacccgg
    13201 accgggagat cgcctgggtg tggggctggt cgctgcgcga cagggtgccc cggctggtgc
    13261 cggagatcct gacgtactac cacgcgccgg gcctggagaa ccggttcgtg caggagagct
    13321 ccaacggctg cgcctccggc ggcagtgcgg ccgaggccgt gtacttcgcc ctgatggagg
    13381 tcgtcgagcg ggacgccttc ctcctcacct ggtacggacg gcagccgctg cccgagatcg
    13441 acccggcgag cagctcccgt ccggcgacgc gcgcgatggt cgaccggctg gcgatgtacg
    13501 gctaccgggc ccggttcttc gacacccgga tcaccttccc gatccccgtc gtgacggcgg
    13561 tcgccgagcg cttcgacggc ggcaccggcc gcatgtgctt cggggcggga gccggtctcg
    13621 acccggagtc ggccctggac tcggcgctct gcgagatcgc cacggacgcc gtcaacctgc
    13681 cggggcgcac cgagcgcgac gaggcccggc tgcgtgccat ggcagccgac ttctccctgg
    13741 tcacggcgct gcacgaccat ccgctcgtct acggggtccc ggagatgggc cggcacgcgg
    13801 acttcctgct gcgggcgccg ggcggggggc cgacgcggac ggtggccgag ctggagtggc
    13861 ccgaccggtg gggcgcggcc gcctcggacg acgtgcgcac ggatctggag cggtgcgtgt
    13921 cggcggtcac ggcggagggc ttcgacgtcg tggtcgtgga ccagacgatg cccgagcagc
    13981 ggaagctcgg cctgcacacg gtgagcgtgc tcgtccccgg gctgctcccc atcgacttcg
    14041 ggtggtcccg gcagcgggcg ctcggcatgc cacggatgcg gaccggcctg ttcaccgccg
    14101 ggctgcgcga gcgcgcgctg gagcccggcg acctgaaccc ggcaccccac cccttcccct
    14161 gacccggccg ccgcgaccgg cgtccgaccc gaacgtagga ggacccatgg gctacgccca
    14221 tgtctacgcc cacgagatca tgcaccgcgg ccgggtgccg atggagcccg ccgacttcgt
    14281 gcccgactgg gccgaccggc cccgcaaggc caagttccac ccggacgccg agaccctgcc
    14341 gctgccggaa tcgccggaac cgccggagca ggccgccggt ggggtccggg ggttcaccct
    14401 gccgctgctg tccgggatgc tccgggactc gtacgggctg accggccggc ggctcgcggt
    14461 ccaggcgaac accgacctgg cggcgctgcc gcactacacc cacgcgaact ggtcgcgggg
    14521 caccgcgtcg ggcggcgggc tctacccggt gtccgtccac tgggcggcgg gcccgggcgg
    14581 gccgctgacc ccggggctct accactacgc gccgcaccag cacgggctgc gccggctgct
    14641 gacgggcgat gtcaccgggg aggtccggtc ggccctcggc ccgggggccg gcgcggccgc
    14701 ggcggcgacg cagtacctcg tcctcggggt gaagtactgg cagaacgcct tcaagtacaa
    14761 cagcttctcc ttccacgccg tgagcatgga cgtgggcgcc ctggtgcaga cgtggcggct
    14821 gtgggccgcg cggtacgggc tgcggatcga cccggtcctg tggttcgacg aggaacgcct
    14881 ggcccggctg ctgggcgtgg cgcccgagga ggaggggatc ttcgcggtgg tgcccctgac
    14941 ctgggacggg gcgcccggtg ccggacaaca gggagctgcc ccggcccccg ccgtcacccc
    15001 ggcccctgag acggccccgg ccgtccggca ccgggacgtc gaacgctccc gccgcgtcct
    15061 cgtgttcgag acgctgcgcc gcatccacga ggccaccgcg ggccgggccg ccgaccgccc
    15121 ggcgccggac gcgctggacg cggccgccgc gttcccgccc cggggcggcg atccgctgcc
    15181 gctgcccgcg ccccccgcgc caccggtcac cacccggcgg gcgctgcgcg aacgccgcag
    15241 cagcttcggc cggttcgacg cctcccgtcc cctcgcggcc gggccgttcg ccgccgcgct
    15301 ggccgactgc gcggccacgg cgtacggcac ggaggccgag cgccccggcg ggcccccgct
    15361 cacctcgctg tacgcgttcg tcaaccacgt cgagggcatc gcgcccggcg cgtacgccta
    15421 cgatccggcc gcccacaccc tgcggctgag ggtgccgggt ccgcccgggt ccttcctcca
    15481 gcgcaactac ttcctgtcca actacaacct ggagcaggcc ggcgcggtga tcgtcccgac
    15541 ggtccgcacc accgcggtcc tggacgcggt gggcgatcgc ggctaccggc tggtgggcgc
    15601 caccatcggc gcggtcgccc agaccttcta caccacggcc gcggccttcg gcctgggcgc
    15661 cggggtggcg ctcggcttcg acaacatctc gtaccgggag gagctggggc tgaccgggac
    15721 cgacgaggcg cccctgctga tcatgctgct ggggcacgac cgtccgcgcc cggccgactt
    15781 ccgtcacgaa atcgcctgag gggagccgac gatgaacacc accgaatggc aggcgggcga
    15841 ccgcttcatg ctccgggtcg ccggactccc gctgtccgcg gtcgaagccc tgcgcgccac
    15901 cgacaccggg cgctgggccg aggaggtcct gaccgccgag gcggccctgc gcaagggcga
    15961 gcagcggctg ggcgacgtgc tccacgaggc cgtcggggcc accgatccgg cgccggacgg
    16021 cccgggcgcc gcccagcggc gcgcgctgct gcggctgcgc cgccagatcc acaacggccg
    16081 cccgccggcc cgccgggacg cgtcgacgga gacggccgtg gaagccgtgg ccgccatgga
    16141 cgaggacgcc gccgagcacc tcgcgggctg gctgcaccgg cgcgggctcc tggacaaact
    16201 gctggccgag ggaccgccgt tgctggccgc cgacctggcc gggaaccggg ccgcgctgcg
    16261 cgagctgctg gccgacgagc ggctgcggca cgggctgctg ctggcctccc cggtgctgga
    16321 gaagcagctc gacgggtacg cgagcgccga gggcgtgccg ggcgggcggg cccgcaaggc
    16381 cgagcggtcg gtcctctcgt acgtgtaccg gacggcttgc aagacgagcc cgttcagcac
    16441 cttcaccggg gtggcgaccg ggcgtttcac aggcgacggc gcacccggcg gcgcggcgcg
    16501 ggtcgcggac gtctggagca gtcacgtccg cctcaacgtc gtggtcctcg cgcggctcgc
    16561 cgagctgatc ctggccgacc ccgtgcgccg ccgggacctg ccgctgcgcc cggcctcggg
    16621 ctggggccac gaggaggacc ggatccgcta cgtgcgccgc tcggtcacgg cgggcgacga
    16681 ctcggccgcc gtcaccttcg acgcggtcaa ggaccggctg ttcttcctgc ggcgcagcgg
    16741 gacgctcgac cgcctcctcg ccctgttcgc cgggcggccc gagctgcggc accgggagct
    16801 gaccgactgg ctggccgccg agcacgccgc ggatcccgcc gagtgcgagg cgtacgtcgc
    16861 cgccctcctc cagctcggca tggtgcgcgt gccctgcctg gacaccgagg tgcacggcgg
    16921 ggatccgctg cgctccttcc agcggtcgct gacctcgctg gagcggccct gggccgaccg
    16981 gctcgccgcc ctgctggagg cgcccgccgc ggcgctggcc ggctatccgg aggccgggca
    17041 cgccgaacgg gccgggctgc tgcgggagct gcgcagcggg ctgcaccggg cgtgggagga
    17101 gctcggcgca ccggacgcgg ccctgccgca gaccctgctg tacgaggacg tgagcgcggg
    17161 ccacgagctg ccctgcgcgc cgccggactg gaccgcgctg cgctcggtcg agcggatcct
    17221 gcccgccttc gacctcacgc tggccgggcg ggtcaccttc gaggggttct tcaccgcgcg
    17281 gtacggctcc gggggccgct gcgaggacct cctggggctg gtgcacgact tccacgagga
    17341 cttctacgac cagtacctgt cgttcaccgc ccggcgcaag cccttcgacg agcgcggcga
    17401 gtacgtcgcg gaggagaact ggctgggcct gcccgggatc cgggccctgg acgcggcgcg
    17461 ccgggcgttc atcggccgga tgcggcgggc ctggtcggcg tacgaggccg cgcacgggac
    17521 gcacggggcg gacggggcgg acgggacggc cgcggaccac atccggctcg acgaggcgga
    17581 cctggcggag gtggcggcgg aactggctcc ggtgataccg gacttcgcgc cgcgctgcca
    17641 ccacctgcag ttcgcccgcg atcccgccga cggcaccccg ctgaccgtcc tgaaccgctc
    17701 gtacggcggc ctggccttcc ccttcagccg tttcacgcac gtgtacgagg agcagggcgg
    17761 gccggggccg acggacgcgc cggacgccgg cttctgcgcc gggctgcggg acaccgcccg
    17821 ccgggtcacc ccgccgggcg cggtcttcgc cgaggtcacc gggggtccgg tcaccaccaa
    17881 cctcaacctg cacggggagc tgaccgacta cgagatcgtc tgcccgggcg agagcggcac
    17941 gctcccgccg gagcgccggc tgcacctgga cgacctgtac gccgagcacg tgccggcgac
    18001 ggggcgggtg gtgctgcggt cccggcggct gggacgcgag gtgatccccg tctacctcgg
    18061 ctacctggtg ccgctcgcgc tgcccgcgat cccgcgcacg ctcctgctgc tgtccccgtc
    18121 gtcgatgtcc ccgctcgacg tctgggcggg cgtaccggag ggcgcggccc tcgaccgggt
    18181 gaccacgcgg ccccgggtgg tccacggcga cgtggtcctc agccggcgca gctggaccac
    18241 cacggcgggc gccctgcccg tccagggggc gcgggaggcc gggcacttcc tcgactggca
    18301 gcgctggcgg cgtacccacg gcctgcccga gcaggtcttc gccaccgtct cggccggccc
    18361 gtcggccgcc ggggccaaac cgcagtacgt cgacttcgcg agcctcctct cgctcgcggc
    18421 cttcgagacg ctgctgcgcg atccggcgca ccgggtcgtc ttccgcgaga tgctccccgg
    18481 ccccgacggc ccgcacgtgc gctcggcccg cggcgcccac gtcgccgaac tggccgtcga
    18541 gacgttcacc tcaaccatcc gagaccagga aggcggcacc cgatgtccga gatgaccccg
    18601 cccgccggcg cccgcaccga cagccccgcc gacacccgtg gcgcgtggca ggccctgcac
    18661 atcttctacg ccgccaaccc gcagccgctg ctgacgcggt gcgtgcggcc gctgatcgcc
    18721 gaactcaccg ccgacggcct gctcgccggc cacttcttca tcaactactg gctggagggg
    18781 ccgcacgtac gcctgcggct gcgccccgtc acgcccgagg cggggcccga ggtgcggcgc
    18841 cgcgccgagg aggccgtcgc cgcgttcctg aaggcccgtc cggccctgta cgaggtggac
    18901 tccgggttcc tcaacgagtt ctacaacacg ctgttcgaca tcgagttccc ggagggcgac
    18961 cgggccgcct tcatgggccc ggacggccgg atgaacctgc ggccgaacaa ttcgtacgcc
    19021 cgggagccct acgagcccga gttcggcaag tacggcggcc cggccggcgt cgaactggcc
    19081 gaatggcact tcgcccgctc cagcgacctc gtcatggacg ccctgcaccg gatgaacctg
    19141 cacctgcgga ccgtcctgct gggcacctcc gcccagctga tgatggtcat ggcgggcgtc
    19201 ttcctgccgg agcgcgagga gctcgccgga tacctcgacc ggtactacga gttctggcac
    19261 cgggccttcc ccggcaccgg gttcatcggg tccgaggagt acgaccggac gtacgggcag
    19321 accgcccccg ggctcggccg ccgcttcgcc gccgtgcgcg gggcgctcgc cgccggggag
    19381 accggccggc tcccggcgtt cctggccggc tgggcggagc actgccggga gctgcgcgag
    19441 cgcgccgagg ccctcgccgt cgccggggac ctggtgttcc gttcctggga cggcgcccgg
    19501 gacgagcggg tgacggatcc cgcgctggcg ctgccgctgc tgctctcccc gtacatgcac
    19561 atgaccaaca accggctcca cgtcaccatc cgcgacgagg cgtacctggc ccatctgctg
    19621 ggccgggtgc tgcgcgagag cgagggcgtg cccgagggcg cggcggtcgc cccgtgaccg
    19681 gcccctcccc cgcgcccggc ccggcgggac tgctcgggca ccggcccgcc ctgcggccgg
    19741 acgtcctgct gtcggcgccg ctgctcaacg gggccgccac cgtccacctg gtcaaggacc
    19801 cggtgtccgg ggcctcgttc gagatcgggc cgaaggagtt cttcctcgtc tcgcggctgg
    19861 acggctcccg cagcctcgcc gagatcggcg ccgcgtacgc gcaggccttc gggcggcggc
    19921 tcggcgaggg caactggcag cagctgctgg ccctgctcgg cacccgccgg ctgctcgccg
    19981 gcgggccgcc gccggccacg cccgcaccgc ccggcggccc gctggagggc accctgctcc
    20041 gcggccggct gcggctggtc gccgacgccg acgccgccac ggcgcggctg caccgggccc
    20101 tgcgcccgct gctgcacccc gtggtgctcg tcgccttgct gctcggctgc ctggccatgg
    20161 aggcggcgct ggccgtctcg ttcggtgaac tggcggacgg gctggggtgg ctgctgcgcc
    20221 atccggcgcc cctgctggcg gtggccaccc tcatgtggct gagcaccgcg cttcacgagt
    20281 tcgcgcacgg catcgcggcc cgccacctcg gcgggaccgt cggcgagatc gggctgcggt
    20341 ggcggctgcc cgtcgccatc atgtactgcg tcgtcgacaa ctaccgcttc ctggcgcgcc
    20401 gtcggcacca ggtggcggtg gcctgcgcgg gcgccttcgc caacctgctg ttcctgctgc
    20461 cgttcttcgg ctggtgggcg gcgctgcccg ggggcgatcc cacccgccgc gcgctcggcg
    20521 cgctcctgct gctcggcagt gcgcaggcgc tcgtcaacct gctgccgctg cccccgctgg
    20581 acggctacac gatgctcggc cacggcctgc gcgtgacacg gctggcgccc gcgagttcgg
    20641 ggtacctgcg gctacggatg cgcgaccggg cggccgccgc cgcgtatccg gcgcgggccc
    20701 gccgcctcta cctggcgtac ggcatcggct ccgcgctgct cgtcctgctg ctcgcggccg
    20761 gcctcacggg agccgtctgg tacgccgtca ccacctgacc ccacgaccga accaccccgg
    20821 gccggcgcga cgtccggacc gcacgcacac acagaggaac gcacgcccca tgacaactga
    20881 cagcacccag ccgcccgact ccccggccat ctccgtccag gacgtgcgca aacgctacgg
    20941 cgaccgtcag gcggtggacg gggtctccct cgacgtgcgc cgcggcgagt tcttcggcct
    21001 gctcggcccc aacggggcgg gcaagaccac cctcatcgag atcatggagg ggctgcggca
    21061 ggcggactcc ggtacggtcc gggtcctcgg gcacagcccc tggccccgcg acaccgcgct
    21121 gctgccccgg atgggcgtgc agacccaggc ctcggcgttc ttcgtgcgcc agagcgcccg
    21181 cgagcacctc gtcaccgtcg ccgggctgta ccgccgcggc ccggaggccg cggaccgcac
    21241 gctggagacc gtcgggctca ccgagcagcg cgacgtcctg gtggagaacc tctcgggcgg
    21301 tcagcgccag cgcctggcca tcgcctccgc cctcgtccac gacccggaac tgatcttcct
    21361 ggacgagccg acggccgccc tggacccgca ggcccgccgc gacctgtggg aggtgctgcg
    21421 cgccctcaag agcgagggcc gcacgatcgt ctacacgacc caccacctcg acgaggccga
    21481 ggcgctgtgc gaccgggtcg cgatcctcgt cgacggccgg acggccgcgc tcgactcacc
    21541 gcaccggctg gtcacggcgg cgggcgcacc ctcccggctg ctgctgccgc aggggcggct
    21601 cggcgtcgag gaggccgccg cgctgcccgg cgtcgaccgg gccaccgtgc agggcggctc
    21661 gctggtgctg gagacggcga cgcccggcaa ggtgctgcag gcggtggacg cgctcaccgg
    21721 gctggacggg gtgatgaccc gtacggcgac cctggaggac gtctacctcg aactcaccgg
    21781 cgccgcacac cccggcgccg cacatcccgg ggccgcagac cccggcgccg cagaaaccgc
    21841 cgccggacac ctcggccccc aggccggccc ccacacgcag acggagcacc aggcatgagc
    21901 gcgtacacgg ccctgaccgc cgccggctac cgggcccagg tccgggacaa ggccaccctc
    21961 ttcttcacct tcgccttccc gctgctcttc ctggtcgtct tcggcctgat cttcagcggc
    22021 caggacgtgg aggagaccgg ccgcccctac atctcgtaca tcgcgcccgg ggtgatgtcc
    22081 tggggcgtcg ccaacgcggc cgtcttcggc atcgccttca ccctgatgca gtggcggcgc
    22141 gacgacctgc tgcggctgat ccggctcacg ccgaccccgc tgacgaccgt gctcgcctcc
    22201 cggtacgtac tggccctcgc cgtcggcgtg gtccaggcgg ccgtgttcgt cgccgtcgcg
    22261 atgctgccgg gcttcgggct gaccctggac ggccgctggc cgctggtgct gcccgccctc
    22321 gtgctcggca tcaccgcgtt cctcgccatc ggggtgatcg tcggcacgta cgcgaacacc
    22381 ccggaggccg tcgccgcgat cgccaactgc ctgatggtgc cgatggcgtt cctgtccggc
    22441 tcgttcctgc cgctggacat gatgccgtcg tggctccggc aggtctcgcg cgtcctgccg
    22501 ctgcgctacc tcaacgacgc ggcgaccggg gccctcaccg gcagcgggtc cctcgccacc
    22561 atcggcaccg gctgcgcggt cctgttcggc ttcgccctcc tcttcggcgc gatcgggctg
    22621 aagaccttcc gctggagcaa ccggacatga cgacgccgtc cgtacgcccc ctcgcccccg
    22681 acgggactcc cctggaggcc gcccgccggg acctcgcccg ggcgctggag ccgctcggcg
    22741 ccgtcgtggt gaccctgggc gtccacgacg ccctggggcc gcgcgccgcc gacccgttcg
    22801 cggcggtccg gcccggggcg acggtgcacc tgaccgcgcg cgaggtcctc gtcggcccct
    22861 ggggcgggga cggcaccgcg ccggcgtgcg gccagtgcct ggcgatgcgc cgccagcggc
    22921 tgcgcagccg cagcgagcgc gacgcgctgg agaccggcgg cgggccgggc actgcggccg
    22981 gccccgaatg gccccggctg tcccggtacg cgtacgacgc cgtgtcggcg ctgcacgcgg
    23041 ccgtccacgg cggtcgggcg ggcgcgcccg gcggggcggc ggcggccgac cgggcgctgc
    23101 cgcaggtgtc ccgcctcgac ctggagacgc tgcggatccg cacgtacccg ctgctcgccg
    23161 acccgctgtg cccggactgc gggccgcggg gcaccgacgc gccccggccc ttctcgcccg
    23221 agtcccgccc caagcccgac cccggcgccc agcggctgcg ggccgcgtcc tcgtacccga
    23281 tgccgtacgc ggcgctggcc aatccggtga cgggggtgct cgggggcggc acctggctca
    23341 acgtcacctc gccgacgacc gcgccggtcg ccgggagcgt gttcatgcgc gggtacgcgg
    23401 gtctgacgga cgtcacctgg agcgggcagg ccaacagctt cgccgcgagc cgcgacctcg
    23461 cccacctgga ggggctggag cggtacgccg gaacccaccg ccgcaccggg aactcgctgc
    23521 tcaccgcctc ctacgcggag ctgggcgacc gcgccctgga ccccgccgag tgcgggttct
    23581 acgctcccga gacctaccgt gacgacccgc tcgtgtcccc cttcgacccg gagcggccga
    23641 tcccctgggt gtacgggcat tcgctgcgcg acgaccggcc cgtcctggtc ccggcccggc
    23701 tggtgcacta cagcgcgggg gtcgccgccg acaacttcgt cttcgagtgc tccaacggct
    23761 gcgcgatcgg cagctgcctg gaggaggcgc tgctcggggc gctgctcgaa ctcatcgagc
    23821 gggacgcgtt cctgatcgcc tggtacggcg ggctgccgct gaccgagatc gacctggcga
    23881 cggtgccggg gacggcggtg cgcacgatgg ccgaccgggc ggcgcttcag gggtacgacg
    23941 tgcacgcctt cgacaaccgc atcgacctcg cggtgccggt ggtgacgggg ctggcggtgc
    24001 ggcgcgacgg cggtccgggg ctgttctcct tcggcgccgg cgcggcgctc gatccggcgg
    24061 cggccgtgga ggcggcgctg tcggaggtcc tcacctacat tccgcacctg ccccgccagg
    24121 tcgaggagcg gcggggcgaa ctggaggaga tggcagggga cttcagccgc gtgcggcatc
    24181 tgaaggacca cgcccagctg tacggtctgc cggcgatggc ggagcacgta cggccctacc
    24241 gggagccggt ggccgtgcgc gcgatggacg aggtctaccg gtcctggacg gagcacgggc
    24301 ggccgcgcac cggcgatttg agggacgatc tgctgtgctg cgtccaggag ttgacgcagg
    24361 ccgggcacga tgtcatcgtc gtcgaccaga ccacgccgga gcagcggcgg atcgggctgc
    24421 gcacggtgtg cgcggtggtg ccggggctgc tgccgatcga tttcgggtgg tcccggcagc
    24481 gggcgccgta cctgccgagg ctgcggagcg cgccgcggcg ggcggggctg cgggcgaccg
    24541 acctgaccga ggcggaggtc cggatggttc cgcacccgtt cccgtaggaa ccgtgaacgg
    24601 cggcgccccg cccctcgctc ggcgaggggc ggggcgccgg tgtccgcgcg gcccggtgga
    24661 tcaggcggaa caggaggtgg tgctggtggt cgaggagcag gtcgaggtcg agctgcagct
    24721 cgtcgaaccg gcgagcacga cctcgctggc gtccgagtag tcggagatct cgaaggtctc
    24781 cgactccagc tccaggatct cctccgcgag cgaggcgagc ggcgacttct ccatggtgac
    24841 tccttctggt gcgggcgggc acggggccgt gccgtgtctg tccccatcag agccggtgcc
    24901 gccgtcaccc gacccttcgc ggcgctgaca ctcctctgac accacgtgtc agcgccctgc
    24961 cgcaccgcct ccggaacggc tgtccgatca tggccgcatg accggccccg taccctcctc
    25021 cgccgccgca cccgcctccc cgcccgtccc cgcgccgctc gcccggctgg acgcgcacct
    25081 gcacgccctg acggcgttct acctggagct gcaccgggat cccgagctgt cgggcgcgga
    25141 gcggcgtacg gcggaccgct tcgccgcccg gctggagtcc gccgggttcg cggtgacgcg
    25201 cggcatcggc ggacacgggc tcgccggggt gctgcgcaac ggcgacggtc ccacggtgct
    25261 gctgcgggcc gagctcgacg ccctgccggt gagggagacg agcggtcttc cgtacgcggc
    25321 cgacggggag gcggcgcacg cctgcgggca cgatctgcac ctggccgcgg ctgcgggcac
    25381 cgccgcgctg ctggccgaga cgccgggggc ctggcgcggc acgctcgtgg tggtggggca
    25441 gccggccgag gagacgctgg agggggcccg ggcgatgctg gccgacggcc tctaccgcag
    25501 gtgcggccgg ccggacgagg tcctggccca gcacgcggcg ccgctgccgg ccgggatggt
    25561 cgcccacggg tacgggcccg tgacggccgg gagcgtcacc ttccgggtgg tggtgcacgg
    25621 ccgcggcggg cacgcgggcg ccccgcacct cgccgtggac ccggtcgtcg ccgcggccca
    25681 cgtggtgacc cggctgcaga cggtggtggc gcgggaggcc gccccggtgg agcaggtggc
    25741 ggtgaccgtc ggctcgttcc gggccgggga ccgggccaac gtcatcccgg accgcgccga
    25801 actggcgctc acggtccggg cggtgagcga ggcctcgctg gcccgggccg ccgaggccgt
    25861 ggaacggatc gtgcgggccg agtgcgcggc cgcggcctgc acccgggagc cggagatcct
    25921 ccgggtctcc gcctccccgg tcacccatcc cgatccggga gtgacggcga gcgtacggga
    25981 ggcgcacacg gccgccttcg gggccgaacg ggtgacgatg tggccgccgt cgctggcgac
    26041 ggaggacttc gccctgttcg gtgacgcggg actggaggtg cacggcgagc ggggcatccg
    26101 gctcgggtac tggatgctgg gcgcggccgg cccggccgcc tggtcccggg cccccggcac
    26161 gacggcggcg cagaagctgg ccgccctgcc ggccaaccac gcgccggact tcgcccccga
    26221 cgtccgtacc gccctgccgg ccggcgtgcg ggccctgacg acggcggcgc tggcccggct
    26281 cggcgccccg tagccgagcc ccaatccccg tccgcggagc atccggaacg gcactatccg
    26341 gtcagcctgg atggatgttc gatgaaccgc gcgcgaccgg cagcaggtca acggcccgcg
    26401 atcggcacgt cactccagcc gtcaccctcc gttttcgcgt gatcgcgaag ggcacacacc
    26461 ccgtccgagc tggccgaacg accattcggt cgccgacatg cgaacggagt gtccggaaat
    26521 cggtcaccga tgtgcgcgcg cccttcagac ccgagagact cggcgacgtc aacccgacac
    26581 accgcagcca aatgctgcac atgtccttcg aattgaaaga gagtcttgtc gtgcgtcacc
    26641 gcatcgctgc tgtctccgcc gccgccctcg tcgccatcgc cggctccatc ggcatcgcgg
    26701 aggctcagcc cgcgagcctg tacgccccgt ccgccgtggt cctcgccgtc gcccagggcg
    26761 agaacgccgc caccgtcgta cgggcgacca ccgtcagctg cgcaccgacc gcccagggca
    26821 cgcaccccga cccgcggggc gcctgcgcgg ccctcaacgc cgccgccggc agcctcgacg
    26881 cgctcctcgc ggccccggac accaaccgtg cctgtccgat gcactacgac cccgtcaccg
    26941 tcaccgcgga cggcgtctgg aagggcagcc gcatcgcctg gaagcacacc ttctccaact
    27001 cgtgcgccat gtccgcgacg ctgaacggga acgccgcctt cgcgttctga tccgccggac
    27061 ctccccccgc gcccgccacc gcctccgtac ccgcccgggt acggaggcgg tggcgggtcg
    27121 cgactcgatc atcgggcgtt gcatccttgg accgagcgcg tacgcgtacc ccgcgccgcg
    27181 ccgcccgagt cacgaggagg atccgatgaa cgccgccgga gagggaccgc agctgccgga
    27241 cgcggtcagc gtcgccaatg ccaagacgac gctcctccag ctgctcgccc gcgcgggcgt
    27301 cttcaccggc gacacggagg aactgatcgg actcgtcgag gccggcgccc tggcccgcgc
    27361 gtacgaggag atcaccgccc gggcggggag cgccccgggg gacaagggcg agccgtacga
    27421 gtccggctgg ctcgacggag cccgcgacgt cgtcgacgaa ctcggcgcga tcgccacccg
    27481 cgccggacgc cgctccgccg gatccgacgc gccggacgag tcccccgagg agcgcccccg
    27541 cgttcggcgg atggagctgg agcgggcgca ggtggcggtc acccccctct acctctcctt
    27601 cacctccgtc tccgacttcg accccgaggt cacctccgag gtcctcaccg cgatcctcgg
    27661 cacgatgagc tccaggcagc gggcccagta cgccggccgg ctcacggagt tcagcgcgtc
    27721 ccaccgggcc cgtctggagc ggctgtacac ggagtacggc cccggcagcc ccatcgcgat
    27781 ccacggccgc tactccgtcg tccactcccc caccagcctc gccgtcctgg aacgcctcgc
    27841 cacggcgccc tcggcgctgc gggaggagtg ggacgccgcc gagctgccgc cggcgtggct
    27901 ggacggcctg acgacggctt ggaacgcgtc ggcctgacgg gggcggcccg gggcgcggcc
    27961 ggcgccccgg gccgactccg gtcgatccgt cagccggcgc cgcgcggcag ccaggccggc
    28021 ggccacgtac ggagcagccc gcccggaggg gtgacggcgg cggccgccac cgacggctct
    28081 cccggattca cgaacggcgg ggtgtcctgc gcgcaccgcg cgccccgcgc cggcagcgcc
    28141 ccggtcacga cgtaccggac gacatggcgc cccacgcagg cgctcgggtt gccgagcgcg
    28201 gtgtgcccgt agccgtcgag cgtcagcaac cgggcccggc cgagctcccg tgccatcgcc
    28261 tctccggcgc ggtagggggt ggacgggtcg tgcaccgagt tgacgaccag taccggatgc
    28321 gcggtgggcc ggttccaggg gccggtgtac gggtcggcgg cccgggccgg ccacgcggcg
    28381 cagggctcgt tggcccacac ccaccaccgg gcgagcggac cggcctcccg caccgcccgc
    28441 tcctccagcg cggggtagcg cccggacggg gcggggttgg ggctctcggc gcacaggacc
    28501 gccagcgact gctcgaaccc gggatagcgg gcgggtgcgg ccacggccgg agactcgccg
    28561 ggcgccactc cctgccacag cgattccagg gtcgcggcgg tcccggacca gcccgggtgc
    28621 acggtgtaga ggccgccccg gacctcgctc accgcgcggg cgtacgtcca gcggccgacc
    28681 ggccgctcgg cgaggcgtgc cagcagggtg gcgtacttgg cccgggtcgc cgccgggctg
    28741 ccggcggaga aggcgcagcc ggtcatcggc gcgcggccgc agaggtcgag gaactgaccg
    28801 agcgtgtcgg cggagccgag gtcggagccc aggcgcagga aggtgctgcg cgcgggctcg
    28861 gcgcccgcgc cgccgtccgt ccacgcccgc gggtcgacgt tcccgtcgac cacgagccgc
    28921 ccgacgcggt cggggaacag gttcgcgtac gtcgctccga gcagcgtgcc gtaggagacg
    28981 ccccagtagc gcagccgttc ctcgcccacc gcccggcgca gcaggtccag gtcgcgcgcg
    29041 gtgtcggcgg tcgagatgtg gcgcagcagc tcggggtccc gccgctcaca ccgctgcgcc
    29101 agctccgcgt aggcggtgac gaacgcctgc cgctgccccg ccccgaccgg gaacggcggg
    29161 accttggcgt gccaggccgc ggcctccttc gccgtgtcga agcagcgcac cgccgtgctc
    29221 tcgccgaccc cgcgcgggtc ccagctgacg atgtcgaagc ggtccctcag ctcggcgggg
    29281 aacttgcggt acagctcggg cagtccgacc gtcccggggc cgccgggtcc gccggggttg
    29341 aagaacagcg atccggcggc gcgccgcccc gccgcggccg cccggtggcg gatcaccgcc
    29401 aggtcgatcg tgcggcccga gggctcggcg tggtccaggg gcaccttggc caccgcgcat
    29461 tcgaagcccg cctgcgcgtt ccgcgtacag ggcttccagc gcagcacgac accgcggccg
    29521 ccgtcaccgc cgtcgccgcc gcccggaccg cccgccgatg ccgggccggc ggccgacagc
    29581 agcgccagca gggcggcggc caccgccccg gcggctgcgc gcagcggtat cgccgtcccg
    29641 gtcgttcgca tcgccggccc ttcgtcgggg aaacgggccc gcgcggtgcc ggcggccctt
    29701 cccgccatga catcggtgcc cggcgcgccg ggcaactcac gggcgtccga acgggcccgc
    29761 gttagctccg tggccgggtg ggtacgcgcg ggacgaccgg cactccgccc ggccaccgcc
    29821 gatcggaacg gagcagtgac atgggacatg gtgcggatgt catcgaggag ctgatgtgcg
    29881 atcaccgtga ggtggacgac ctgttctccg cgatcgaacg gaccgccccg gcgctcgacc
    29941 ggcagacgct ggccgagcag ctcacgatcg aactcgtacg gcacgcggtc gccgaggagg
    30001 agcacctcta cccggcgatc cgcgagcact tccccgacgg ggagctcatc gcggacaagg
    30061 agctcgcgga ccacgcccgg gtggagagga tgctgaagga cctcgaaggg gtggacggcg
    30121 cgggcctcga attcgaccgc cggatcgccg agctccgggc cgaggtgacc gcgcacgtgt
    30181 gggacgagga gcagaacctc ttcccgcggc tgcggcaggg gtgttcgccc gaggacctgc
    30241 accggctcgg cgacaaggtg cgccgggcca agaagttcgc gccgacgcgg ccccacccgg
    30301 gggcgcccgg caccccgccc gcgggccggc tgccggcgcc cgtgaccggt ctggtcgacc
    30361 gcgcccggga cttcgtctcg ggccgcggcc ggtagcggcg cgccgggcgg tccgcgttgt
    30421 ggccggcgcg ccgtccgctg ttcacccccg gtgggaggag gcgcggattc ccctgcgcgg
    30481 ccgccgcccg ggaacaagcc atctcgcccg gcacagccga ttgccccggc gcggcgggga
    30541 gcgcgccggg gggaacgctg gcctgctgtg cccgggctcc cgccccgggt gccgcaccga
    30601 ttcggcactc cagtgggaac cggccatccc ctcctgcgat attgcggtgc cgggaatcgt
    30661 ctccatagcc tgacggggca tcaaaagtcc ctcaagcatt ggcccgttcg agccgctttt
    30721 ggcccgcggg aaggctctcg caagccgtgg aggggattac ccatgagcgc gcccagcaca
    30781 cgccccttgc tttcgctcta tcgagccatt tacgcggcag cagtcaccgc gaccctcctg
    30841 gtggcgggtt tcggattgtg gaccggcctc agcctgcgga gctggccggt ggcactcgtc
    30901 tcggtggccg ttgccggact cctggttctc gccgtacgca ggcgtctgac cgaattccgg
    30961 tcccggcggc atctgcccgg gccgaaaccg tcgttcttcc tcggcaatat gagcgatctg
    31021 ctgctccacg gccacggcgg tcggcacgaa tccctccagg cgctgcacga cgagtacggt
    31081 cccctcgtgt gtttccatgc cgcttgggga agcgccccgt tcgtgtcgct ctcgtacgtg
    31141 tccccgaacc tcctcaggaa ggaactcgac tcgcaccgcc gggccgaccg gaccgtgctg
    31201 tcccggagcc tcatgggaat ggcggggggt gaactccacc agacccatcg gcaggtcatc
    31261 gcaccctcca tggccttccg cggcgtgtcg gaacgcgggt ccgtgctgaa ggacgtgtcc
    31321 gaccggtacg tggacaagtg gaagcacgtc gacgaggggt acgagggcct ccagtccgac
    31381 ctgcgcgact ggagcgtgaa ctgtctcagc gccttcctct tcggcgacga ctgggacgtc
    31441 ggagcggacc tgcacgcgta ccaccgcgcg ctgagcgcca tcgaggagga ggtgagcttc
    31501 cgggccttcc accccttctt cgtcaggtgg gtcttcccga ggcggcggcg ccgggtgagg
    31561 gccgcctacc accgcgtcgc ggcggaactc ggcgaggtcg tgacccggcg tgagcagcgg
    31621 atccccgccg cctgcccggc ccacggggcc accggcgccg cagcggccac cggcgccgcc
    31681 ggcggcgatc tgctcgaccg ggtgacccgg gcgccgtggt ccgccgagga ccgcgtcgag
    31741 gagctgatgt cgttgatcct cggcggcgcg gatccgatgt cctacgtgct gtcccaggcc
    31801 ctggtgatgc tctccctcga tccgcacgtc caggagaagg cgcggaagac gatcgaggcg
    31861 tcctcgtcct gcgcccagga gggtgatccc ggcccggacc cttacgtccg caacatcgtc
    31921 tacgagacgc tgcgcatgtt cccgccggtc cccttcagcg cgaagttcag cgacgaacgc
    31981 gccgtggtgg aacagggcat gagcatcccg ccggggaccg tcatcatgtg gatgaagaac
    32041 gccgtcggga agaacccgga aatcttccgc gaggcggagc ggttcaaccc ggaccgcttc
    32101 gacccggagc ggttcccggc ggacggcgag aagcggaacg acaccatctc cagcttcctc
    32161 cccttcggtg ccggcccccg gcactgcgtg ggaaacaggc tcgccgagca gcagtgcatc
    32221 gtgctgctga cggaaatcct gaagaacttc cacgtcgtgc ccctgcggca catcaaggtg
    32281 cagttccatt ccacgatctc cgtggtgcca tcggccgtac cggtcaggct ggtcccacga
    32341 tgaaaggacc agagatgacg gaaggcggcc ggaccgcgcc gatcgcgttg ggccgggacg
    32401 agggagaagc cctgtggttc ctcgatttcc tggcgaaggt gaagggctcc tccgcggaga
    32461 tgaacggagc ctcgtcggtc gtcgagttcc tcggccggag cggctccggt tcgcccctgc
    32521 acgtccacca tcacgacgac gaatggtggt acgtcctcga cggggagatg acgttctggg
    32581 tggcgggccg ggaattcccg gcgacccccg ggtcgttcgt ctacggccct cgccacgcgc
    32641 cccacacgtt cctcgtcact tccgaggagg cgaggttcct ccatgtgacc gaacccggcg
    32701 gattcgacgg cttcctgcgt gaactggcgc ggcccgcgcg gtccctggag attccgtcgg
    32761 acgtgaacgc gctgccggac ctggagcaga tcctcgccgt cgcggccccg tacgggatcg
    32821 aggtgctcgg tccgcccggc atcccggccg cgctccccga ccccggaacg cagaaggaag
    32881 gcaggacacc gtgaccaagc cgtccccgct ctcggacccg ggcatcgtgg ccgaccccta
    32941 tcccgtctac gcccgcctgg ctcggcgcga accggtccac tgggacgaag ggctgaacgc
    33001 ctgggccgtc atgaagtacg ccgactgcgc ggcagcgctg aaggaccccc ggctcaaggc
    33061 cgagcggatg gaggaggtgc tggaggtcaa gttccccggc gagccgctgc cgcccgacga
    33121 catctaccac cggttcacca agaacgtcat gatgtacacg gatccgccgc tccacgacgc
    33181 cctgcgcagg tccacccagt cgggcttcac ccgggccgcg cacgagcact acggccaggt
    33241 catcgagcgg gtcgcggccg acctcgtcgc ctcggtgccc ggcgggacga gggagatcga
    33301 cgccgtcgcc gcgttcgccg ccgaactccc cgtgcgctcg gccgtgtccg ccttcggggt
    33361 gccggaggaa gacctggcct tcgtcatccc gtgcgtggag acgctcatga cgtactggtc
    33421 cgggccgcag gaccagccgg tggaactcgg ccgcctgctg gaactcctcg cggacctcca
    33481 cacgtacgcg ctcgaactca tcgagggcga gcggggcaag gtcctcccgg acacggtcat
    33541 cgcacgcctc gcggcggccc aggacggtct gacggagacc acgccggagc agacggtgca
    33601 ccagctggtg ctgctgttca tcgcgttgtt cgcgcccacc acaccgggct ccctcagcag
    33661 cggcatgctc tccttcgcgc ggaacccgga ccagatcgcc cgcttcctgg cggagcccgc
    33721 ctgcgtggag aacacggcga acgaggtgtt ccgccacaac gcctcgaacc agttcacctg
    33781 gcgcgtcgcg acgacggacc tcgacgtggg cggcgtacgc atcgggaagg gccagagcct
    33841 cgccctcttc ctcggcgcgg cgaaccggga ctccgaggtg ttcgagcgcc ccgacgtgtt
    33901 cgacctcggc cggcccaaca gcgccaagca cctctcgttc ggccagggcg tccacgcgtg
    33961 cctcggcagg cagatcgccg gcctccagct caagtggttc ttcgtcgcgc tcttgcgccg
    34021 tttccccgcc gtccggccgg ccggtgagcc cgtctggaac cagaacctcg aattccggtc
    34081 gctgcggtcg ttaccgctca gcctccgctg aagcccccac ttcggcgcca cgcctccgcg
    34141 aggaaaccgt gaactccacg cccctgcccg caccgacccc gacacgtgcc cactccgcca
    34201 ccgcccggcg acccgggacc gttgccgtcg ccgaacgcga cgaggcggag gagttcctcc
    34261 gccagttcca cacggagcac cccgagcaac ccgtccccct cgcccggcgc ctgcaccagg
    34321 tccgcgccgc catcgacacc gcgggtacct accggcacac ccccggcgaa ctcgccttcg
    34381 gcgcccgcgt cgcgtggcgc aactcccgcc gctgcatcgg ccggctgtac tggaacagcc
    34441 tgcgcgtcct cgaccgccgc gaggcgaaga cccccgggga gatccaccgg tacctgtgcg
    34501 atcacctgcg ccaggccacc aaccgcggcc gcatccgccc cgtgatctcc gtcttcgccc
    34561 ccgacgcacc cggccggccc ggcccgc
//
