LOCUS       NZ_CP011664            20912 bp    DNA     linear   CON 03-MAR-2024
DEFINITION  Streptomyces sp. Mg1 chromosome 1, complete sequence.
ACCESSION   NZ_CP011664
VERSION     NZ_CP011664.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. Mg1
  ORGANISM  Streptomyces sp. Mg1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     De Novo Assembly of the Streptomyces sp. Strain Mg1 Genome Using
            PacBio Single-Molecule Sequencing
  JOURNAL   Genome Announc 1 (4), e00535-13 (2013)
   PUBMED   23908282
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUN-2015) Biochemistry and Biophysics, Texas A&M
            University, 300 Olsen Blvd., College Station, TX 77845, USA
REFERENCE   3  (bases 1 to 7868178)
  AUTHORS   Hoefler,B.C., Konganti,K. and Straight,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JUN-2013) Biochemistry and Biophysics, Texas A&M
            University, 2128 TAMU, College Station, TX 77843, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 8.2
            Genome Coverage                   :: 30X PacBio; 80X Illumina
            Sequencing Technology             :: PacBio + Illumina MiSeq/HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 08:10:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,822
            CDSs (total)                      :: 7,726
            Genes (coding)                    :: 7,467
            CDSs (with protein)               :: 7,467
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 260
            CDSs (without protein)            :: 259
            Pseudo Genes (ambiguous residues) :: 0 of 260
            Pseudo Genes (frameshifted)       :: 109 of 260
            Pseudo Genes (incomplete)         :: 200 of 260
            Pseudo Genes (internal stop)      :: 18 of 260
            Pseudo Genes (multiple problems)  :: 60 of 260
            CRISPR Arrays                     :: 11
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:43:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 30255
            Orig. end                         :: 51167
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011664.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Paul Straight
            (paul_straight@tamu.edu).
            Annotation modified by the submitter.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20912
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="nucleoside"
                     /region_number="1"
                     /rules="(LipM or LipV or LipU or TunD or pur6 or pur10 or
                     nikJ or nikO or truD)"
                     /tool="antismash"
     cand_cluster    1..20912
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /kind="single"
                     /product="nucleoside"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20912
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10912](-)"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10912)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
     misc_feature    complement(327..341)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 21.34"
                     /tool="antismash"
     misc_feature    complement(1269..1284)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.04"
                     /tool="antismash"
     misc_feature    complement(1270..1283)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            1564..2211
                     /locus_tag="M444_RS00140"
                     /old_locus_tag="M444_00140"
     CDS             1564..2211
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019524915.1"
                     /locus_tag="M444_RS00140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00140"
                     /product="HNH endonuclease family protein"
                     /protein_id="WP_008736412.1"
                     /transl_table=11
                     /translation="MIKKLRRGLLATALAFAVLTPTSPAQADEVTLMDGITALPVADEI
                     REGYKRELYPHWKDDDKNGCTARNDVLIAEAIEAPTVGAGCALTGGVWHSYYDDVLVQG
                     PSGVDIDHLIPLAEVHDSGGYGWTTERRRRYANDLGSDVTLVGVSARSNRQKADQDPAT
                     WMPMASVHCRYLGEWVATKHRWGLAVDRAEREALLRYAASCPNARITYEPAT"
     misc_feature    2384..2402
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     gene            2850..3305
                     /locus_tag="M444_RS00145"
                     /old_locus_tag="M444_00145"
     CDS             2850..3305
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466938.1"
                     /locus_tag="M444_RS00145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00145"
                     /product="lamin tail domain-containing protein"
                     /protein_id="WP_234008743.1"
                     /transl_table=11
                     /translation="MLTPRTRRLAAGAAISAATLLLLPGQAHAAGALRISKIWYDSPGS
                     DTRTNASLNGEWVQITNSTSTAVSLKGWTLTDASRHAYTFPTFTLKPGKTVTIKTGRGT
                     NTTTTLYQQRSAYVWNNDKDTATLRRTNDTLHHTCAYNSTRHDYKTC"
     gene            complement(3602..4030)
                     /locus_tag="M444_RS00150"
                     /old_locus_tag="M444_00150"
     CDS             complement(3602..4030)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675660.1"
                     /locus_tag="M444_RS00150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00150"
                     /product="DUF6086 family protein"
                     /protein_id="WP_037790254.1"
                     /transl_table=11
                     /translation="MSQYYDIGDQTLWNPSNGASRLFMSQVSVYQAELGLPSGIGLMRA
                     DECQIDPLVFKAFVDALLAWHRGTSHAVMAALSEGFVATVLVLAERAGIEVKWQPTSFP
                     GVGGLKDVQVPTARSSSEAAWAAALQQKSRDLSRFMAV"
     gene            complement(4267..4932)
                     /locus_tag="M444_RS00155"
     CDS             complement(4267..4932)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="M444_RS00155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_047960364.1"
                     /transl_table=11
                     /translation="MPNRRRAIDPSHPLGRFARQLRELQASARARAGSSDRAREISIDK
                     VAVNGTPWSTSRTAIYAALNGTRLASPDTLCAIVTAWDHRGGDGITEWLRIRDQVEEDL
                     IKLRSSTTPMATPSGRSESDLVRLGTPTPHRALAPSRGRLHNAAALKELKRRLQDARAK
                     GGLSMTQVAARGGLARTTLHMAFNGDGVPSAATVASLARVLKLDQEDLLRMRAAVLAE"
     gene            5098..5256
                     /locus_tag="M444_RS41825"
     CDS             5098..5256
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M444_RS41825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158512282.1"
                     /transl_table=11
                     /translation="MLNRTRGRKPVQSAETKTRVQLLAAAIQGVFSGASRAGTKWVIRD
                     KQMAGAA"
     gene            5349..5519
                     /locus_tag="M444_RS41830"
     CDS             5349..5519
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M444_RS41830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158512283.1"
                     /transl_table=11
                     /translation="MAILFCMVCAGLTGVIAFSLARHLGAEPLVSLGWAGGTFIGAYYL
                     VQNILEKFGQL"
     gene            5669..5800
                     /locus_tag="M444_RS43705"
     CDS             5669..5800
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M444_RS43705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_008736400.1"
                     /transl_table=11
                     /translation="MSVEHLNRLSDELTERMLRWSLRAMVLKDPDLPNKIPPCVTRR"
     misc_feature    complement(5812..5827)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.29"
                     /tool="antismash"
     misc_feature    complement(5824..5839)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.69"
                     /tool="antismash"
     misc_feature    5825..5838
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            6045..6401
                     /locus_tag="M444_RS00165"
                     /old_locus_tag="M444_00160"
     CDS             6045..6401
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008734401.1"
                     /locus_tag="M444_RS00165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00160"
                     /product="DUF6233 domain-containing protein"
                     /protein_id="WP_008736396.1"
                     /transl_table=11
                     /translation="MSVLPPDLPRLRTLVTYLRGELSRMEQALAAAEGRKAATVRKQAQ
                     PAPEPEPEPEPPAWLVERGIGVGRLPVRAHAGDCWDTRSRCAPASADQIRALLAQGIPA
                     CPHCRPDTALGVLE"
     gene            6425..6655
                     /locus_tag="M444_RS00170"
                     /old_locus_tag="M444_00165"
     CDS             6425..6655
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008734407.1"
                     /locus_tag="M444_RS00170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00165"
                     /product="hypothetical protein"
                     /protein_id="WP_008736394.1"
                     /transl_table=11
                     /translation="MTESQPKVVVYPPDAQGGRRVRADGEILGRALNPRALLEFLRRAG
                     LDPDSVRLDDPLLIDWRGGGPAAWSPDTSEE"
     gene            complement(6735..7109)
                     /locus_tag="M444_RS38370"
     CDS             complement(6735..7109)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="M444_RS38370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124289540.1"
                     /transl_table=11
                     /translation="MRKTIYAVTVAAVVFAAAPAHANAKAKDGQVGLSVYGKGLRVEEV
                     GAHMQGHGTGVRARLITYDPDGYRSAFTGWKDATPVSAALTKLSTVGWKWKEGKKFAHG
                     TRLCVEFNVVQGEPCAVIHR"
     gene            complement(<7974..8396)
                     /locus_tag="M444_RS42650"
                     /pseudo=""
     CDS             complement(<7974..8396)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007261917.1"
                     /locus_tag="M444_RS42650"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPSSSPPTTASAWSSQLLSEDPAVDSVLCLARRGRRCGL"
     gene            complement(8575..9879)
                     /locus_tag="M444_RS00180"
                     /old_locus_tag="M444_00175"
     CDS             complement(8575..9879)
                     /EC_number="2.5.1.7"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF006873.0"
                     /locus_tag="M444_RS00180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00175"
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="WP_037796812.1"
                     /transl_table=11
                     /translation="MNDQTFLLPLTDTRAIRITGGHRLQGTTSVQGSKNIALHLYAGAL
                     LADEPLTLTGIPHILDTQVCSEILTRTGTPTRIVGDRFETAPATAWHPAVPDELGGRIR
                     TTAVLAAGLLARAGRVRFPLPGGDAFCHRLIDRHLAAMEAAGATLDITGTHVEAHLTGR
                     GPQPFTTNVTTQKWGPSLGATVTAMLLAARARGTSTILHPNAEPEVLATASMLAAGGVG
                     IAWEGTTALQVTGTDHITGGSFPVPPDRLEATTLLLAAAITGGTVHLDNFPVSGFTAAL
                     VATLTDAGIELAPANGGTLAQCPAGPRCVQTATTSATCTDIQPQLTAFLTQAPGTSRIE
                     ERIYTSRATHVDPLRALGADVTADGPTITVHGPSPLTAAHVASQDIRAVAALVTAALAA
                     EGTTTIQGIYHLQRGYGSLLPKLASLGAELTVTQK"
     misc_feature    complement(9859..9861)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..10912)
                     /locus_tag="M444_RS00185"
                     /old_locus_tag="M444_00180"
     CDS             complement(10001..10912)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     nucleoside: TunD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF027681.4"
                     /locus_tag="M444_RS00185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00180"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_050779255.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.2e-10, bitscore:
                     37.8, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="TunD (E-value: 2e-155, bitscore: 515.3,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 8e-10, bitscore:
                     36.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVLITGGAGFIGSALTQALRIAGHSVTPLDNLSVTSRRPSPTGL
                     MVRDVRSLTAQDLGRVDTVVHLAALKSVPESFEVGGFEHNVEVDRHMLHIFTDSTARRL
                     LLASSCEVYGQQSGPLSENTPHAPRSPYAAGKVATELLADIYRPRLEDGRQLGIVRFFN
                     TFGPHEDPDAVVPAFLDAVAENRPLTIEGDGTQARDLTYIEDAVTMLTRILDAPALLPV
                     VNCGSGHAVSISDLARAVIRTAGRGTITHTAPRINEISSFTADQTLFARMYGPIDRMPL
                     DKALALSVQTRARTLAAAVPGR"
     misc_feature    complement(10972..10985)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            11128..12411
                     /locus_tag="M444_RS00190"
                     /old_locus_tag="M444_00185"
     CDS             11128..12411
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468697.1"
                     /locus_tag="M444_RS00190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00185"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_106433248.1"
                     /transl_table=11
                     /translation="MGQETSDLGAIFRSARHALRLKQVDVARAVGYSPSAISRIEGNRM
                     RVDLDTRLRLAQVLRIPPERVSGFPVPAGPVIDTVGNVPMPNEEDAMRRRTLLGALAAG
                     ASAVVGTGTAAASPAAAVDLNDVLFRLPSADPAPLQALAAKTASARQAFTAARYNDLGN
                     SLPGLLAAAEATRESAAGRARQQANAVLARAYVLASELAAKQHSDAAWVAADRALAAAR
                     ASGMPIPVGEAARVLAITMRRSGNCSSAVRFLATEAAALDPAQERTGAVRTTLLLTAAY
                     SAAAGGDRATALTLLDEADETVERRPQAPGGLFTVDATKTQAAVYRIGVHNTLGTPDEG
                     VEIARSLNIGLMPTAERRARAWTDTARMWHTLGNSQQAFAALSHVEQEAAQEVRRPALR
                     ALTSSLLYSPARVQGLREFAVRTGAVPA"
     misc_feature    11149..11151
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11182..11184
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12457..12939)
                     /locus_tag="M444_RS00195"
                     /old_locus_tag="M444_00190"
     CDS             complement(12457..12939)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985693.1"
                     /locus_tag="M444_RS00195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00190"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_008736377.1"
                     /transl_table=11
                     /translation="MIPDFVSDLRKAVGPDCLLWLPGVVGVVLDEHGQVLLQRRSAAGL
                     WTPLSGILEPGEAPAAGVAREVAEETGVRVVVERLAAVTSSPPVRHGNGDRAQYLELVF
                     ACRPADPGQEPRVCDDESVEVGWFALDALPPMSERMRELIGLVEKDEPQAWFAPSP"
     gene            13377..>13700
                     /locus_tag="M444_RS00200"
                     /old_locus_tag="M444_00195"
                     /pseudo=""
     CDS             13377..>13700
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982757.1"
                     /locus_tag="M444_RS00200"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00195"
                     /product="UDP-glucose 6-dehydrogenase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRISVIGCGHLGIPHAAAMAELGHEVIGVDVDQAKVDSLNSGQCP
                     IYETGLPELLARHTASGRLRFTTDNREAAAFADMHSIGVGTPIDADGRSYDTGQVYGAI
                     HQLA"
     gene            complement(14762..16387)
                     /locus_tag="M444_RS00205"
                     /old_locus_tag="M444_00200"
     CDS             complement(14762..16387)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008736107.1"
                     /locus_tag="M444_RS00205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00200"
                     /product="ISAzo13-like element ISStsp1 family transposase"
                     /protein_id="WP_008736107.1"
                     /transl_table=11
                     /translation="MRIPDETRDQLSAKFAVLFPHLDERQRRLLMGAEARLLGHGGIRA
                     VARAAQVSETTVRDGVFELESGDEPLGRVRRPGGGRKRVADLDPGLRPALLALVEPDER
                     GDPMSPLRWTVKSTRTIAAELARAGHRISADTVGDLLREEGFSLQANAKTLEGNQHPDR
                     DTQFRYLNEQARNHRDAGQPVISVDTKKKELVGDFKNSGRQWRPAGEPVPVSVHDFADP
                     QLGKAVPYGIYDLTANTGWVNVGTDHDTAAFAVESIRRWWHGQGQAAYPRATRLLITAD
                     AGGSNGYRTRAWKLELAQLAAETGLTITVCHLPPGTSKWNKIEHRLFSHITMNWSGRPL
                     TSHEVIVQSIAATTTRTGLRVRAELDTNTYPTGVRIKDAEMAALPLTRHAFQGAWNYAL
                     HPQPSPVIPAARAPQTPDPEWNQALLSDPALTGMTLQQLNDLTETLAPDGDIRRGRPPR
                     LAFPDQVLATVLHLRAALAAEPLAVLFGTSRTAMHRTLLKNRRLLETHSITIPPATTPP
                     TALAALQARVQAQTSEDNKIKTTC"
     misc_feature    complement(16707..16721)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     gene            complement(16719..17624)
                     /locus_tag="M444_RS00210"
                     /old_locus_tag="M444_00205"
     CDS             complement(16719..17624)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019356463.1"
                     /locus_tag="M444_RS00210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00205"
                     /product="phosphotransferase"
                     /protein_id="WP_008736371.1"
                     /sec_met_domain="APH (E-value: 1.8e-08, bitscore: 33.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAALAPGGFDEFEMHQVLKRGCAAVGLDSSEARLLRGHTNAVI
                     HLVKEHVVVKIARKGSRIDDVARTVRFVRWLMDAGFPTVSLHPVDQPVGVGQHALTFWE
                     YLPQPSDPVPAAQLAKPLYSLHTLPASPEALPAHDNLAAIRRSLKSITCLSDEALAFLN
                     GSTEQLESALHVVQFELPEGVIQGDPQHRNALHTASGGAVLCDWDTVAIGQPEWDLVTV
                     EVHCRRFGHGSQHYEAFANTYGWDVTRWSGYQTLAAIRELRMITTNARKVSDAPTSLQE
                     VERRVEGLRCHDRALRWNIL"
     misc_feature    17639..17653
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.77"
                     /tool="antismash"
     gene            complement(17657..19054)
                     /locus_tag="M444_RS00215"
                     /old_locus_tag="M444_00210"
     CDS             complement(17657..19054)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963084.1"
                     /locus_tag="M444_RS00215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M444_00210"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_008736369.1"
                     /transl_table=11
                     /translation="MDRTPHGPSCAKRLRQEATTHGESCSQIAFTIHAHCSVSLLRAHR
                     LARGLTLKEAAEGLNALTAGHKGAPRVDADQLGHWETDRQPRPATLVLLCNYYGGLRPE
                     DLGFESAEAAVPASVPSTMVLVERALPWPAAPRAEIVDESLERQVDAVRRSVDRTLAAG
                     TVNSNQLDLLDEQVMWAREQYVYTPPAPMVKVLLDQLEEVESLAADRQPAAVQVRLSEL
                     TAILATLVADALMKLGYLPRSRSWYATARHAADDSGNTELRARVRAQAAMLPFYYGPLE
                     AAVALAREARIISRGRPSATAALASAAEARALAKLGDAEGAESALRYATVAFEQSGAGG
                     SGDNEAFGFPERRFRLYESGTLTALGHTSWARRVQEEAIRLYPSRTGIDPALLNLETAL
                     CLAQEHSLREACQLAGDTLLRVATEHRTPIVEERAREVIGALPPGAEASRAVHELREIL
                     ALPSGHM"
     misc_feature    complement(19013..19015)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19133..19900
                     /locus_tag="M444_RS40675"
     CDS             19133..19900
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="M444_RS40675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_158512284.1"
                     /transl_table=11
                     /translation="MGVSEQVTDPHDVKLRFSKRITHPNDVRLRISEPSLLLGTVFRRI
                     LPISEAQQAARQPANLTPRLAGSRRTPPHQTASVPRRGDVCRHPDREVDTLTRLSSRQF
                     LAVLVHGDGVDRVAVEFESQRSNVGEARRFVRQRLVAWGLDEDDALIDRVVLVLSELVT
                     NAVVHGRTRPSNESEAVGVALAFKPNFAFGLMVTDNSSSYPIPTIRPSAGAIRGRGLVL
                     VNAHSDCWTSAPRKEGDCPGKAVWAFFHCAQPT"
ORIGIN
        1 gcagatgcct gtacggctcc cctggctcga tttcccgcgg ctcaccctgt ccgtcccccg
       61 gccgcaggaa gtcgttgcgg agctgctcaa gcaggtcacc tccagcagcg cgccgtccat
      121 cccgggaacg atcgggatga ccgtcaccga gcagtccgac atcagcgtcc tgcggggctt
      181 cctcgtggtc gaggctctga ccgcgctgaa gaccgagcgc acggagcact tcctcaagga
      241 actgcgtcgc ctcaacgagg gcaagtaccc cgactggcta ccactggagg atgcaaagga
      301 gcttgcccgg gagttcggag ggcgccagga acggaaattc caatcggcga cgaacgtgct
      361 caacggatgg accgctgctg atgtgacccc ggcgctggag accgcgtgcg cccagggctg
      421 ggccgagcgt ggtctgggtc tggactgcga ccagtgcagc ctgaacagct tcatccccct
      481 gcacgccacg ggcgggaccg cggtgtgtcc tgcgtgctcc gctccggcgt tgtatcagcg
      541 ggagaacggg aaggccgtcg agatcgtcta ccgcctcaac ggcttcatcg accgggccat
      601 cgacaacggc gttctcccgc acctgctcgt agcagccgcc cttagggacc tcgacccctc
      661 cacctacctc ctgcccggcg tcgacgtggt catcgacgac acgaagaacg aggtcgacgt
      721 cttcggcatc catgagggca aggtcctcgc gggcgaggta aaggtcaagg cagcagaatt
      781 cgccaaggat gaccagattg tccgagacgt tgcactcagc cgacgactcg gggcagacat
      841 ccacctcatg gccgccaccg acatcatcga cgacggcctc cagagccagg cgcgcgagct
      901 gtgcgagagc tacgggctcg aactcctcgt cctccacgaa ccgcagctcc gtcccggtct
      961 cgcagaccag cgtgacgccc gggaccgacg gaaagaggcg gcggcagtcg ccagcacgcc
     1021 ccggccccgc cggggagaca ccaaggcgcc ctccacttct ggcccggcgc ccaggacgtg
     1081 agggcgaagg ttcccgaggg cgaacccgtc gcccgaggaa gggaggcgga ttggccgcgc
     1141 agggggccgt cagagggcgg caggtgcctg tgctcccgcg gtatcgacgc tcgttgatgt
     1201 ggagctgcga cgacagcgaa acctgacctc ctggtttcgg gttcccgagg catgagcgat
     1261 gacaacaacg tgatcacgat caaaatccgg ggccacgaga agccgccctc gaagcggtac
     1321 accggatctc ggccctgttc ctgtccagcg ggccgtgccg actgcggcgc acgcccggcg
     1381 aggacgaagt acaggttctc gtccacgcgg acgtcgcaag aggtgccggt gagggcggct
     1441 acctcgaccc tgacgacgct gagggcgcag gcgcgtttct gcggtgaacc ggctcaccca
     1501 gcggagtgag ccctcaccaa cccggctcga tccggtggcc aatgacgcgg tatcaccggt
     1561 ttcatgatca agaaattgcg tcggggcctg ctggccaccg ccctcgcctt cgccgtgctc
     1621 acccccacct cccccgccca ggccgacgag gtcacactca tggacgggat caccgcgctg
     1681 ccggtcgccg acgagatccg cgagggctac aagagggagc tgtacccgca ctggaaggac
     1741 gacgacaaga acggctgcac cgcccgaaac gatgtcctga tcgccgaagc catcgaagca
     1801 ccgaccgtcg gcgccggctg tgccctcacc ggcggggtgt ggcactcgta ctacgacgac
     1861 gtcctcgtcc aggggccgtc cggagtcgac atcgaccacc tgattccgct cgctgaagtc
     1921 cacgactccg gcggctacgg ctggaccacc gaacgccgcc gccgctacgc caacgacctc
     1981 ggctccgacg tcaccctcgt cggcgtctcc gcccgctcga accggcagaa ggccgaccag
     2041 gacccagcca cctggatgcc catggcttcg gtccactgcc gctacctcgg agagtgggtc
     2101 gccaccaagc atcgctgggg tctcgccgtc gaccgggccg agcgggaagc cctcctgcgg
     2161 tacgcggcgt cctgccccaa cgcccgcatc acctacgaac ccgccacctg accctgaagg
     2221 ccgcgacctg gccgcgacct ggccgcggga cggagggtgc cactaccgcc cgcggtcagg
     2281 ctggccggga gtggatgctg ccgccccggg cggtgaccgg ctacgtgtga cggctgccgg
     2341 acctgcccgc ggccggcagc accacggggc cgggagcggc ccttcaggta cggctccccg
     2401 cagcctctat tccactgccc ttcccggcag atccaccgcg tgacgcgcag acgcagggct
     2461 tgggccccac ccgtacggag tgtcctctga cacgcgatcc tgaccgattc acaagtgatc
     2521 gtgacgggtg gcgcgagcgg gcgcagcggt cggatcgccg agcggcttgc tgctgtgcct
     2581 gtgccggtcc ggtgtcgatg ggcactcacc cgcgacgact cccgtcggga aggcagaggc
     2641 cggatgtcgg ccgattccct cggcgccgac caagcactgc gcgggcgggc ggttgggcgc
     2701 tgacggccgc gcgagacgca tcaacaccac agggtgacgt tctgtcacaa gatggccaca
     2761 gagcctccgc agggaggccg gcgcccttag cgtccgaggt ctgcaccgcc ggccatacgg
     2821 cggtcccgtc agacaggatg cgccctctct tgctcacgcc ccgtacccgc cgcctcgccg
     2881 ccggcgccgc catcagcgcc gcaaccctgc tcctccttcc cgggcaggcg catgccgccg
     2941 gagcgctgcg gatctcgaag atctggtacg actcccccgg cagcgacacc cgcaccaacg
     3001 cctcgctcaa cggcgagtgg gtccagatca ccaacagcac cagcaccgcg gtcagcctca
     3061 agggctggac cctcaccgac gcctcccgcc acgcctacac cttccccacc ttcaccctca
     3121 agccaggcaa gaccgtcact atcaagaccg gacgcggcac gaacaccacc accacgctct
     3181 accagcagcg cagcgcctac gtctggaaca acgacaagga caccgccacc ctccgccgca
     3241 ccaacgacac cctccaccac acctgcgcct acaactcaac ccgccacgac tacaaaacct
     3301 gctaaacccg agagcccgcc gcaagagacg gctgccggac gggtcgtcgt tcagccgggc
     3361 agagcgccct ggcccggctg acacacgcga tggccgtcct tccgtagacg gcggtcagct
     3421 acatgggctc cagccaccga accggacgag cagcgcgcgg ttctgttcga tgttcagtcc
     3481 gggggctgcc gctaccgcct cgggctgttg cgcgcgggcc agtgggcggg cggccttgag
     3541 cgcggcggtc ggggactgtg cggtgagggt tccgagtcct tcgcgggcgt cggcggcggg
     3601 cttacaccgc catgaagcgg ctcaggtcgc gtgacttctg ctgaagggcg gctgcccaag
     3661 ccgcctcaga ggaggatcgg gccgtcggga cctgaacatc cttgaggccg ccgacaccgg
     3721 ggaagctcgt tggctgccat ttcacctcga tgcctgctcg ctccgccagg accagcaccg
     3781 tggcaacgaa cccctcggac agggcagcca tgacggcgtg actcgttccc cggtgccacg
     3841 caagcagagc gtcgacgaac gctttgaaca cgagggggtc gatctggcac tcgtcagccc
     3901 gcatgagtcc gatgccggac ggcagaccca gttccgcctg gtagacgctc acctggctca
     3961 tgaacagacg ggaggccccg ttggacgggt tccacagggt ctggtcacca atgtcgtagt
     4021 actggctcaa ttcagcccct ccctgctggt cataccggcc agcatcgcga gcacatgaca
     4081 ttacgatcag tcagccctcc acggaaagcg agacagaacc cgagaaagag aggcgccggt
     4141 ccgaaccgga gagtcacccg acaccggggc agctgtgccg ctgctgcggg taccccgccg
     4201 ttcgtcttgg ttcaactgaa caggaacgaa ctccccggat gcacgactac gagatcgcgt
     4261 gaccgtctac tcagccagca ccgccgcgcg catccgcagg aggtcctcct ggtcgagttt
     4321 cagcaccctc gcgagggagg ccaccgttgc ggcagacggt acgccgtccc cgttgaacgc
     4381 catatggaga gtggtgcgcg ccagtccgcc acgagctgca acctgcgtca tgctcaggcc
     4441 gcctttggcc cgggcatcct gcaggcgcct cttaagctct ttgagcgccg ccgcgttgtg
     4501 aagccggccc cgagagggcg cgagagcccg atgaggagtc ggtgtcccga gacgaacaag
     4561 atcggactcg ctgcggccgg aaggcgtggc catgggcgtg gtggacgacc gcaacttgat
     4621 gaggtcttcc tcgacctgat ctcggattct cagccactcg gtgatgccgt cacctccccg
     4681 gtggtcccag gccgtaacga tggcgcacag cgtgtccggt gaggctagcc gggtgccgtt
     4741 gagggctgcg tagatagctg ttctgctggt ggaccatggc gtgccgttca cggcgacctt
     4801 gtcgatgctg atctctctgg cacggtcgct gctccccgca cgggctctcg cgctcgcctg
     4861 cagctcacgc agttgccggg caaacctgcc cagcgggtga gatgggtcga tggcacggcg
     4921 tcggttgggc actcattccc ccacatatga agtcccgtca agtcccatgt gataccacgt
     4981 gataccagat tcggaacaga gggcatcccc cgtgcgtaga tggaagcggc ccgccgaaag
     5041 gcgtccaacc acaccggcgg gccgcgtcgg atccacacct gcgaaagggg agacccagtg
     5101 ctcaaccgta cgcgtgggcg gaagcccgtg cagtccgccg agaccaagac tcgggtgcag
     5161 ttgctggcgg cagcgatcca gggagtgttc tccggcgcct ctcgtgccgg cacgaaatgg
     5221 gtgatccgcg acaagcagat ggcaggtgcc gcgtgaccac ccccgccccg acgaccccgc
     5281 ccaacccccc gaccccggga ccgccggcca gtaccccgcc caatggaccc accaccggca
     5341 cgaagatcat ggcgattctg ttctgcatgg tctgcgcggg cctcaccggg gtgatcgcct
     5401 tctccctcgc ccgtcacctc ggagcggagc cgctcgtctc acttggctgg gccggcggca
     5461 cgttcatcgg cgcctactac ctggtgcaga acatcctgga gaagttcgga cagctgtgag
     5521 ggccccggcg acgcccctac ggggcgtcgc ccacggccct gccccgccag ggcatcaggg
     5581 ccttccgccg cggacctgcc ctttctccgg gccgctgatc acagaggagg cttacgacaa
     5641 agagcccacc ggcttccgga tcaagccgtt gtccgtcgag cacctgaacc gcctttccga
     5701 cgagctgacc gagcgcatgc tccgctggtc gttgcgagcc atggtcctga aggatcccga
     5761 cctgccgaac aagatcccac cctgcgtcac cagacggtga cctgcacaga ctcgcccaga
     5821 caatcgaaca tgcgatctaa taggagtgac gtcttccgca ccgcccagga gcacacaatg
     5881 accacccccg aaaccccagc cagaccgcag gccgtcacct gggcaccgag ccaaaccggc
     5941 ccctgctcga aatgccacgc ccccacatgc cgatacgggg gcggcgcctc gcccttgtgc
     6001 gcgtcatgca aggccgcgcg tcaggcgcag tacgggggct gagcatgtcc gtcctgccgc
     6061 cagacctccc ccgcctccgg actctggtca cctacctgcg cggcgaactc agccgcatgg
     6121 aacaggccct cgccgccgcc gaggggcgca aggccgccac cgtacggaag caggcgcagc
     6181 ctgcgcccga gcccgagccc gagcccgagc ccccagcatg gctggtcgag cgcgggatcg
     6241 gtgtcggccg cctcccggtc cgcgctcacg ccggggactg ctgggacacc cgcagccgct
     6301 gcgccccggc cagcgccgac cagatacgcg ccctgctcgc ccagggcatc cccgcatgcc
     6361 ctcactgccg gcccgacacc gccctcgggg tgctggagtg aatcaccgac ctcaaggtgg
     6421 aaacatgacc gaaagccaac caaaagtggt cgtctaccca cccgacgccc agggcgggcg
     6481 acgcgtccgc gcggacgggg aaatcctcgg ccgcgccctg aacccccgcg ccctcctgga
     6541 gttcctgcga cgggcaggcc tggacccgga tagcgtccgc ctcgacgacc cgctgttgat
     6601 cgattggcgc gggggcgggc cagccgcctg gagcccggac accagcgagg agtgagcgca
     6661 gcagtgcggg ccgccactcc gtaagggcgg cggcctgcgc tgcgccggtc agcggttgtt
     6721 gccgcaggga ccggctaccg gtggatcacc gcgcacggct ccccctgcac gacgttgaac
     6781 tccacgcaca gccttgtgcc gtgggcgaac ttcttcccct ccttccactt ccagcccacc
     6841 gtggagagct tggtcagggc cgcactcacg ggggtggcgt ccttccaccc ggtgaacgcc
     6901 gaccggtacc cgtccgggtc gtaggtgatc aggcgggcgc gtacaccggt accgtggcct
     6961 tgcatgtgcg ctcccacctc ctcgacccgc aggcccttgc cgtacacgga caggccaacc
     7021 tggccgtcct tggctttcgc gttggcgtgc gcgggagcgg cggcgaatac gacggccgcc
     7081 accgtcactg cgtagatcgt ctttctcatg ccggttcaac cgggtgcggg acggcaaggt
     7141 caccccgcgg aggccgcggc gacctgttcc cgtgcgagga catcggcccg gcggtcgtcc
     7201 tcgccgaggg tagcgagcat gtccgccagg ggggccggcg aggtcagcgg cggcctccgg
     7261 gccctcctcc ccgagcaggt gccagacagc atgcacgtta cgggccgtgc gcaccgtgtc
     7321 ggcctcaggg cggtgttgcg cggcccggca gcgcaaggcg gtcgcgatga acaattccct
     7381 ggttccgtgc cagtcggcgc gccggcagag ggcgagccac gcgcgggcga tgagcaccgg
     7441 gatggtggca tctgactccc cggaccagcc actcagggcc gtctctagct cgcaggcggc
     7501 ggtgacagct gcgggcaggt ccccggccgc gtgatgggcc cacacggccg cccacatctc
     7561 ccgatagctc ggcacggcta cgaggaggtc gcgcagcacg agcgcacccg gcacaccgcg
     7621 gccgaatgtg gtaaacgcat gagcctgcgc gcaccgcagc cgcagttccg gcgtctgctg
     7681 gaactgaccg gcgccgatgc cacattgcgg acagcatctg tccacaggtg cgtgcacctg
     7741 aagttcctgg tgcggctccc cgggcttcga ctgggtgctg gagctgaccg gcgagccctg
     7801 cggctacgcg ttcaccgcgc ggcctgcggc gcgcatccca gcgttcgggc tgccgcggcg
     7861 gagcgaacct cctctagcgt ggtgctctgc cgctcgccgc agtccagcag gacgtcgagg
     7921 tcgtcggcgt ggaggcgcgc tgtcggtttg ggccagggcg cgcagggtgc gccagccttc
     7981 tcgcgggtgt aggcagcctg tggccagccg tgcgtgggcc acgattcgtc aaccgcccag
     8041 tccttgggtc cgggtgagta cgcgccgacc gagtaagcgt ggatcagggc gggacgcccg
     8101 cagcggcgac ggcgtcgaag acgcgcatgc tgccgaggac gttgatgcgc catgttgcgg
     8161 ccgggtgatg ggtgggctgg acttccaggc gaggtggatc acggcgtcgg taccgtggaa
     8221 cagccgcatc aggtcggctc cgcccggctc gacgtcagct gcctgccagg tggtcgtcac
     8281 aggccgcaac gacggcccct ccgtgccagg cacagcaccg aatccacggc cggatcctcg
     8341 gacaggagct ggctggacca ggcgctcgcc gtggtgggtg gcgaggacga cggaatccat
     8401 gcccatgggc cccaggcgtc gccgacgaag cggggtgcat cgtgttcggc gggcgcaggt
     8461 cgccggacgg gggcgccgat ggtggccgcc gagctcgggc cgggcagctt gctggggttg
     8521 atcacctgcg acgcgaccgc agggagcggt cgcgttcttg cgtgccttgg gttcctactt
     8581 ctgtgtgact gtcagctcgg ccccgagtga ggcgagtttg ggcagcaggc tgccgtagcc
     8641 gcgttgcagg tggtagatgc cttggatggt ggtggtgccc tcggctgcga gggcagcggt
     8701 caccagggcg gcgacggcgc ggatgtcctg gctcgccacg tgggccgcgg tgagggggga
     8761 cgggccgtgc acggtgatgg tcgggccatc ggctgtgacg tcggcgccga gggcgcgcag
     8821 ggggtcgacg tgggtggcgc gggaggtgta gatccgttct tcgatgcggg aggtgccggg
     8881 ggcctgggtg aggaaggctg tcagctgggg ctggatgtcg gtgcaggtgg cggaggtggt
     8941 ggctgtctgt acgcagcggg ggccggctgg gcattgggcg agcgtgccgc cgttggcggg
     9001 ggccagttcg attccggcgt cggtgagtgt ggccaccagc gcggctgtga atccggagac
     9061 ggggaagttg tcgaggtgga cggttccgcc ggtgatggcg gcggccagga gcagcgtggt
     9121 ggcctccagc cggtctggcg ggacggggaa ggagccgccg gtgatgtggt cggtgccggt
     9181 gacctggagg gcggtggttc cctcccaggc gatgccgact ccgcctgccg cgagcatcga
     9241 ggcggtcgcc agcacctcgg gttcggcgtt ggggtggagg atggtggagg tgccgcgggc
     9301 gcgggcggcc agcagcatcg cggtgaccgt ggctccgagg ctcggtcccc acttctgagt
     9361 cgtcacattg gtggtgaacg gctggggacc ccggccggtc aggtgggcct cgacgtgggt
     9421 gccggtgatg tccagggtgg cgccggcggc ctccatggcg gccaagtgcc ggtcgatgag
     9481 ccggtggcag aaggcgtcgc cgcctggcag ggggaagcgg acccggccgg ctcgggcgag
     9541 caggccggcg gccaggacgg cagtggtgcg gatacgcccg cccagctcgt ccgggacggc
     9601 ggggtgccag gcagtggccg gcgcggtctc gaagcggtcg ccgacgatcc tggtcggggt
     9661 gccagtacgg gtgaggatct ccgagcagac ctgggtgtcc aggatgtgcg ggatgccggt
     9721 cagggtcagc ggttcgtcgg ccagcagggc gccggcgtac aggtggaggg cgatgttctt
     9781 gctgccctgg accgatgtcg tgccctgcag acggtggccg ccggtgatgc ggatggcgcg
     9841 ggtgtcagtg aggggcagta agaaggtctg atcgttcacg gattccttcc ccgtgggcgt
     9901 ggggcgtgtt ggagggggct cgcggtcccg gcccggcatg ggtgccgggc cgggaccgct
     9961 agcagcacgg actgcctgtc cgcgcgggtg ggggtggcgt tcagcggccg ggtacggccg
    10021 ctgccagggt gcgcgcgcgg gtctggacgc tgagagccag cgccttgtcc aggggcatgc
    10081 ggtcgatggg cccgtacatg cgggcgaaca gggtctggtc ggcggtgaag gaggagatct
    10141 cgttgatccg gggggcggtg tgggtgatgg tgccgcggcc ggcggtgcgg atgaccgcac
    10201 gggcgaggtc gctgatggaa accgcgtggc cggagccgca gttgacgacg ggcagcagcg
    10261 cgggggcgtc caggatgcgg gtgagcatgg tgaccgcgtc ctcgatgtac gtcaggtccc
    10321 gggcttgggt gccgtcgccc tcgatggtca gcgggcggtt ctcggcgacg gcgtcgagga
    10381 aggcgggtac gacggcgtcg gggtcctcgt gggggccgaa ggtgttgaag aacctgacga
    10441 tgccgagctg gcggccgtcc tccaggcgcg ggcggtagat gtcggccagc agctcggtgg
    10501 cgaccttgcc cgccgcgtac ggggagcggg gggcgtgcgg cgtgttctcg gagagcggtc
    10561 cgctctgctg gccgtagacc tcgcacgagg aggccagcaa cagccgcctc gcggtcgagt
    10621 cggtgaagat gtggagcatg tgccggtcga cttcgacgtt gtgctcgaac ccgccgacct
    10681 cgaagctttc cgggacggac ttgagcgcgg ccaggtgcac aaccgtgtcc actcggccca
    10741 gatcctgtgc ggtcagcgac cggacgtcgc ggaccatcag gcccgttggg ctcggacgcc
    10801 gggaagtgac cgacaggttg tccagcgggg tgaccgagtg ccctgcgatg cgcaacgcct
    10861 gggtgagggc cgaaccgatg aagccggcgc cgccggtgat cagaacgttc aagggtgcct
    10921 ccgcaaaggt gggagcagcg aaccgggctg gtgtgccggg cgtctgctgc cgcaaccgtg
    10981 gtgcctgacg cacccgtccg ggagctggta tcggcgcgct cgcacgtggg gtgcgggagc
    11041 ggcacacggt gtgcgcctgt acgccctgtt gccgtttggc gacaggcagt actgtcatgc
    11101 ttccccgtcg gtgcgcagga ggtacccgtg ggccaggaga cgagcgactt aggcgcgatc
    11161 ttccgcagtg cacgccatgc tttacggctg aagcaggttg atgtcgcccg agctgtcggt
    11221 tactccccgt ctgcgatctc gcggatcgag ggcaaccgga tgcgcgtgga cctcgacacg
    11281 cgtctgcgcc tggcccaggt gctccgcatc ccccctgagc gggtcagcgg gttccctgtc
    11341 cctgcgggcc cggtgatcga taccgtgggg aacgtaccga tgccgaacga ggaggatgcg
    11401 atgcgtcgca ggacactgct gggggcgctc gctgccgggg cgtcggctgt tgtcggcacg
    11461 ggcacggctg cggcctcgcc cgctgcggcc gtggacctca acgacgtgct gttccggctc
    11521 ccgagcgccg acccggcgcc gctccaggcg ctggccgcca agacagcctc cgcgcgccag
    11581 gcgttcaccg ccgcccgcta caacgacctt ggcaactcgc tgcccggcct gctggccgcc
    11641 gccgaggcga ccagggaatc ggccgccgga cgagcccgcc agcaggccaa tgccgtcctc
    11701 gcccgcgcct atgtcctggc ctccgaactc gccgcgaagc agcactccga cgccgcgtgg
    11761 gtcgctgccg accgcgctct ggccgccgca cgggccagcg ggatgcccat ccccgtcgga
    11821 gaagccgccc gcgtactggc catcaccatg cggcggtccg ggaactgctc ctcagccgtc
    11881 cgtttcctcg ccaccgaggc ggccgcgctc gacccagccc aggagcgcac gggagccgtg
    11941 cggaccacgc tgttgctcac cgcggcgtac tcggcggctg ccggcggcga ccgggcaacc
    12001 gcgctcactt tgctcgacga agctgatgag accgtcgagc gccgcccgca ggcacccggc
    12061 gggctgttca ccgtcgacgc caccaagacg caggccgccg tttaccgcat cggcgttcac
    12121 aacaccctcg gcaccccgga cgagggcgtg gagatcgcac ggagcctgaa catcggcctc
    12181 atgccgaccg ccgaacgccg cgcccgggcc tggaccgaca cggcccgtat gtggcacacg
    12241 ctcggcaaca gccagcaggc tttcgccgcg ctgtcccatg tcgagcagga ggcggcccaa
    12301 gaggtgcgtc ggccggcact gcgggccctg acatcgagcc tgctctacag cccggcgcgc
    12361 gtgcagggcc tgcgggaatt cgctgtccgc acgggagccg tgcccgcata gcggcctgac
    12421 tccgccccgg cgccggggag ctggtccggt gcccggtcac ggcgacgggg caaaccacgc
    12481 ctgaggctcg tccttctcga ccagcccgat gagctcccgc atccgctcac tcatcggcgg
    12541 cagggcgtcc agcgcgaacc agccgacctc caccgactcg tcgtcacaga cccggggctc
    12601 ctgacccggg tccgccgggc ggcaggcgaa cacgagttcc aggtactgcg cccggtcccc
    12661 gttgccgtgc ctaaccggcg gggaagacgt caccgccgca aggcgttcca ccaccacccg
    12721 gaccccggtc tcctccgcca cctcccgcgc caccccggcg gccggagcct ctccgggttc
    12781 caggatcccg ctcaacggcg tccacagacc agcagcggac cggcgctgca ggagcacctg
    12841 cccgtgctcg tcgaggacca ccccgaccac ccccgggagc cacagcagac aatcgggacc
    12901 gaccgctttc cgtagatctg acacaaaatc aggaatcatg ccctcaccct agggcgagga
    12961 gcggactgcc ggcgggcttt cagaacactt ctcccccgga catcgcccgc gccccgacgc
    13021 tcacaccgcc cggcctccac cgcgcacgga accgcctgaa cagcagttct ccccagcatc
    13081 accggacccg cgggggctcc gccgtgctgt atccgtgcct ggcaatatgc ggcgagctcg
    13141 accaccctgg cctccggccc cgtccggatg gctcctggtt tgaatacccg ctggaggccc
    13201 cgcagagcgg tgacgtggtc gtacggcaga cggccgccgc tgcggtcggc gagctggagc
    13261 ggctgctgag cctcgcgtga ccagcacgtg agccggcggg gccggggaac agcgctagcc
    13321 tctgggctcg ttccccggcc ccgtacacgg gcccctccca ggatgagagt caaggaatgc
    13381 gtatttcggt aatcggctgc gggcacctcg gtatcccgca cgcggcggcg atggccgaac
    13441 tgggtcacga ggtcatcggc gtggacgtcg accaggccaa ggtcgacagc ctgaactccg
    13501 gccagtgccc catctacgag accggtcttc ccgagctgct tgcccgtcac accgcgagcg
    13561 ggcgcctgcg gttcaccacc gacaaccgag aggcagccgc gttcgccgac atgcactcca
    13621 tcggcgtcgg cacccccatc gacgccgacg gccgttcgta cgacaccggg caggtctacg
    13681 gcgccataca ccagctcgct cgtccgctac ggctggcgga cccaacgtag tacatcatca
    13741 ggagtacggc cccgacggcc agcagccgga ggcccgtctg tcccaggcca tccgtcccag
    13801 cgtcgtgggc cagcccggca ctctgacggc cttcgccgtc cgctcccaag ccccggccgc
    13861 gcccaaatcc tctcgggact caccggtgag ttcatacgag gcacccgggc gggtcaccgg
    13921 tgagttcgca caggcgctgg tgaggtcacc aggcaagtca ctggcagccg caggagtatc
    13981 ggtcagttca ccagcggccg gtgagttcct ggcagatggg cgctctggcc tggggcggaa
    14041 ggtttgcaga gtcaccggcg agtcaccact cgggctgtac gagcctggcc gcattgggga
    14101 ccgccagaag cgcggcgagt ccgtggccgg ccaagccacc gcgtgtcata gcccttcccg
    14161 cccgcattac agcccgagcg tcctgtccca catcccactg cggcttggtc cggtcacgcc
    14221 tcgacggcgg gtaccgtgcg gctctgaggg accggtgggc agccttcttc ctcgatcacg
    14281 ctcaccggca gcaggagttc tcccgtccca ccgggttcgc cggggtccgc ttcgcgcgag
    14341 ccaggccgag cgcctgcact tgggtgccca gccggaccgg cccgtgtgcc aggtgcggat
    14401 ctcctcgcgt atgggaaggc gctccggcat cgcccttgcg cgtcgtgcag ggccgcgcgt
    14461 caggcgcggt aaaggggctg agcgtccgtc ctgccgccgg atttcccccg gctgcagact
    14521 ctggtgacct acctgcgcgg cgaactcagc cgcacgggga caggccctcg ccgccgcagg
    14581 ggagagcgag gccgccaccg cccgcgaaca gcccgccgcc cgagacaggg ttgcgaccga
    14641 ggccggaaca cccccgcagg cgcggggtcc acggtttctc cctgacggac gatccctggc
    14701 tgctcggacc atccccgcgg gcgcggggtc cgcacttcct gagctaaggg attgcagatc
    14761 attaacacgt cgtcttgatc ttgttgtcct cgctggtctg tgcctggacc cgggcctgaa
    14821 gggcggcgag ggccgtgggt ggggttgtcg ccggtgggat ggtgatgctg tgtgtctcga
    14881 gcagtcgccg gttcttcaag agcgtgcggt gcattgcggt gcggctcgtg ccgaacagca
    14941 cggcgagggg ttccgcggcc agggcggccc gtaggtggag cacggtggcc aggacctggt
    15001 cggggaaggc cagccggggc gggcggccgc gccggatatc cccgtccggg gccagggtct
    15061 cggtgaggtc gttcagttgc tggagggtca tcccggtcag tgcgggatca gagagcaagg
    15121 cctggttcca ctccggatcc ggcgtctgcg gggcccgggc cgccgggatt acaggtgatg
    15181 gctgggggtg cagtgcatag ttccaggcgc cctggaacgc gtgccgggtc agcggcaggg
    15241 cggccatctc cgcgtctttg atacggactc cggtcgggta ggtgttggtg tcgagttcgg
    15301 ccctcacgcg cagtccggtg cgggtggtgg tcgcggcgat cgactgcacg atgacttcgt
    15361 ggctggtcag cgggcggccg ctccagttca tggtgatgtg cgagaacagc cggtgctcga
    15421 tcttgttcca cttcgaagtg cccggtggta ggtggcacac agtgatcgtc agcccggttt
    15481 cagcggcgag ttgagccagc tcgagcttcc atgcccgggt gcggtagccg ttggatccgc
    15541 cggcgtcggc ggtgatcagg agccgtgtcg ctcgcgggta ggcagcctgg ccctggccgt
    15601 gccaccagcg gcggatcgat tccacggcga acgcggcggt gtcgtgatcg gtgccgacgt
    15661 tgacccagcc ggtgttcgcg gtcagatcgt agatcccgta ggggacggcc ttgcccagct
    15721 gcgggtcggc gaagtcgtgg acgctgaccg ggacgggctc gccggcggga cgccactggc
    15781 ggccgctgtt cttgaagtcg ccgacgagtt ccttcttctt ggtgtccacg ctgatgaccg
    15841 gctggccggc gtcccggtgg ttgcgggcct gctcgttgag gtaacggaac tgggtgtccc
    15901 ggtccggatg ctggttaccc tcgagcgtct tcgcgttggc ctgcaggctg aagccttcct
    15961 cccgcagcag gtcgcccacg gtgtcggcgc tgatccggtg cccggcccgg gccagctccg
    16021 ccgcgatcgt acgggtcgat ttcacagtcc accgcagcgg cgacatcggg tcgcctctct
    16081 catcgggctc gaccagcgcc agcagtgccg gccgcagccc cgggtccaga tcggcgaccc
    16141 gtttgcgtcc tccgccggga cgccggaccc gccccaacgg ctcgtcgccg gattccagct
    16201 cgaacacgcc atcgcggacc gtcgtctcac tgacctgggc cgcccgagcg acagcgcgga
    16261 tgccaccatg ccccagcagc cgggcctcgg cccccatcaa cagccgtcgc tgccgctcgt
    16321 ccagatgcgg gaacaacacc gcgaacttcg cggagagttg gtcacgggtc tcgtccggga
    16381 tgcgcatacc agaccaacga gccccaggtc aggaagcaac accttgatga tctgcaatcc
    16441 cttaggactc taccggcaag gcggctgttc tcattcagtt agtttctcgt gatccccgcc
    16501 atgacagcca gaccactgag ctgcaactgc attgccctgg acggaaccac catcggctgc
    16561 agcacgccaa ggcccaaagc ccgagttcct gcgtgaacac caccatcacc gtctgctgaa
    16621 cctcgcgcca gggccctctc ccccgcaact accccttcgc tggcctcggg cccctgaacg
    16681 tcttttaggt ttggctgata tggaactggc cgagaacgtc agaggatgtt ccaccgcagg
    16741 gcgcgatcat ggcaacggag tccttctacc cgccgctcga cctcctgaag gctggtggga
    16801 gcgtctgaaa ccttccgagc gtttgtcgtg atcatgcgta gttcccggat cgcggccaac
    16861 gtctggtacc cggaccaccg cgtgacatcc cacccgtacg tgtttgcgaa ggcttcgtag
    16921 tgctgcgacc cgtggccgaa acgcctgcag tggacctcca ccgtgacgag atcccactcc
    16981 ggctgtccga ttgcaactgt gtcccagtcg cagaggacgg ctccgccgct ggcggtgtgc
    17041 agagcgttgc ggtgttgtgg atctccctgg ataacaccct ccggcagctc gaactgcacg
    17101 acatggagcg ctgactcaag ttgctcggtg ctgccgttca ggaacgcgag cgcttcgtcg
    17161 gacaggcatg tgatcgactt gagggaccgt cggattgccg cgaggttgtc atgcgccggc
    17221 agggcctcag gcgaagccgg cagcgtgtgg agcgagtaca gcggcttggc cagctgggcc
    17281 gccggcactg ggtcggacgg ctgaggcaga tactcccaga acgtgagagc gtgctggccg
    17341 acgcccactg gctggtcgac cgggtggagg gagacggtgg gaaagccagc atccatcagc
    17401 cagcgaacga accggacggt acgagctacg tcgtctatgc gtgatccctt tcgggcgatc
    17461 ttgacgacga catgctcttt tacaaggtgg ataaccgcgt tggtgtggcc gcggagcagg
    17521 cgagcctcgg aggaatcgag gccgacggcc gcacacccgc gcttcaggac ctggtgcatc
    17581 tcgaattcgt cgaacccgcc aggggccagc gcagcttgtg tcatgggtca aggctcgccg
    17641 acgatccggt ccgctgtcac atgtgtccgg aaggaagcgc aaggatctcg cgcaattcgt
    17701 gcaccgcgcg gctggcctcc gcacccgggg gaagtgcccc gatgacttcg cgggcccgct
    17761 cttccacgat cggagtgcgg tgctcggtag cgacccgcag gagggtgtca ccagctagct
    17821 gacaggcttc cctgaggctg tgctcctgag ccaggcagag tgctgtctca agattgagca
    17881 gagcggggtc gatgccggtt cttgacgggt ataggcggat ggcctcctcc tggacacgac
    17941 gtgcccagct cgtgtggccg agggcggtca aggtgccgct ctcgtagagt ctgaatcggc
    18001 gctcagggaa cccaaacgct tcgttgtcgc cagagccacc cgctccgctc tgttcgaacg
    18061 cgacagttgc gtatcggagt gcggactcgg ctccctctgc gtctccgagc ttggccagag
    18121 cgcgtgcttc ggctgccgaa gcgagtgccg ctgtggcgct gggacggccg cggctgatga
    18181 tcctggcttc ccgggcaagg gcaaccgccg cttccagggg gccgtagtag aagggaagca
    18241 tggcagcctg tgcccgtact cgggcgcgga gctccgtgtt gccgctgtcg tccgcagcgt
    18301 gccttgctgt ggcgtaccac gaccgggacc ggggaaggta cccgagcttc atcaaggcgt
    18361 cagcgacaag ggtcgccagt atggcggtca gctcggacag gcgaacctgt acggccgccg
    18421 gctgcctgtc tgcggcgagg ctctcaactt cctcaagttg gtcgaggagc accttgacca
    18481 tgggcgctgg aggtgtgtag acgtactgct ctcgtgccca catcacctgt tcgtcgagca
    18541 gatcgagctg attcgaattc acggttccag ccgcgagtgt gcggtcgacc gagcgccgca
    18601 cagcatcgac ctgccgctcc agggattcgt cgacgatctc agcacgcgga gcagcaggcc
    18661 agggcagagc gcgttccaca aggaccatgg tggaaggtac cgaggcaggt acggccgcct
    18721 ctgcgctctc gaagcccagg tcctcagggc gcagaccgcc gtagtagttg cacaacagca
    18781 caagcgtggc cggtcgtggt tgcctgtctg tctcccagtg ccccagctga tcggcgtcaa
    18841 cccgaggagc acccttgtgc cccgcggtga gtgcgttcag tccttccgct gcttccttca
    18901 gcgtcagccc acgtgcgagg cggtgggcgc gcaggaggga cacagagcag tgggcgtgaa
    18961 tcgtaaaggc aatctggctg cacgactcgc catgtgtggt ggcctcctga cgtaaccgct
    19021 tcgcacagga tgggccgtgt ggtgtgcggt ccaccagtac ctcctcaacc gggctcgctc
    19081 atcaaaatcg tagtgacaac tcgtcgactc tgtgtcaaga acagtgactt ccgtgggggt
    19141 cagtgaacag gtcactgacc cccacgatgt gaagttgcgg ttcagtaaac ggatcactca
    19201 ccccaacgat gtgaggttgc ggatcagtga accgtcactg ttgctcggca ccgtcttcag
    19261 gcgaatcctt cctatctcgg aagcccaaca agctgcccga cagccggcga acctgacacc
    19321 ccgactggcg ggctcgcggc ggacgccacc ccaccagacg gcttcggtgc ccaggagggg
    19381 cgatgtctgt cgccacccag acagggaggt ggacacgttg acacggttgt cgagtcggca
    19441 gttcctggca gtactggtgc acggtgacgg cgtcgaccga gtcgccgtcg agttcgagag
    19501 ccagcgcagt aacgtgggtg aggctcgccg tttcgtccga cagcggctcg tggcttgggg
    19561 gctggatgaa gacgacgctc tcattgaccg agttgtcctc gtcctgagcg agttggtcac
    19621 caacgccgtt gtccacggac gaactcggcc gtcgaatgag agcgaggccg ttggcgtcgc
    19681 gctcgccttc aagccgaact tcgccttcgg gctcatggtg accgacaact ccagcagcta
    19741 cccgatcccg acgatccgcc cgtctgcggg tgccatccgg ggacggggtc tggttcttgt
    19801 caacgcccat tccgactgct ggacctcagc accacgcaag gagggggatt gcccggggaa
    19861 ggccgtgtgg gccttcttcc attgcgcaca gccaacgtga cccgaggcct ccgtcaacgg
    19921 ctgggcctcg tcgcattgat gctgacgaca accgccgcgg gcgcgatcac cctggccacc
    19981 tagccagtcg acaccgttcc ggatggacca cgagccgaag agcagccctg cgaaggggcc
    20041 agtgccacgg ccacccccca gccccacccc cagcattttc gcggccacca gaagcccgcc
    20101 cccgccggtg ctcgccgcgc cctccgcctg gtgccgccct cagcacccgc aggcagctgt
    20161 cccccactcc ctacgcgacc agcgagaacc ccatgtgtaa ccacgcgtcg ccgtgcccgg
    20221 cagctgaccg cgataccacc ctcaccgcca cccgcagccg tctgccacgg cgacgcagtg
    20281 acgccccccg aaaggaaccc cgacatgagc acggccagcc cgaaggatcg cgcgttacgg
    20341 cgctacctgg ccgagcagtg gagtgatgtc ccggaccagg tcacgacgga actgccacag
    20401 cctggaaccg caccaactgc ggaaactgct cagcagcctc gttggagccg gcatcaccgt
    20461 cagggtgatc gcagaccgct cccccaccga gcacgtggtc gccttcagtc gcctggacga
    20521 ccaggcgctg ccactcatcg ggaggccagt atgaccaccg cggccgacaa catccgggaa
    20581 cggagacccg agaacgccat gcatatccac gacatttcga tgcaagccgc gacatcggct
    20641 cgcctctacg accatttcgc gggcggctgc gaagcctacg ctatcgatcg ggacctcgcc
    20701 gccagggcga cggccgtcgc tccctggctc tcctggagcg cccacaccgc acgcgagtac
    20761 gcccacactg cggtttcccg gatcctggac gacaccgaca tccgccagtt cctcgacctg
    20821 ggctgtgggc tgccagccgc ggacggccga cccctcgtcg agctggtcag taagaccacc
    20881 caacccggcc caggtcggtc cccgcagtac cg
//
