LOCUS       NC_021252              22148 bp    DNA     circular CON 28-MAR-2024
DEFINITION  Amycolatopsis keratiniphila, complete sequence.
ACCESSION   NC_021252
VERSION     NC_021252.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis keratiniphila
  ORGANISM  Amycolatopsis keratiniphila
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
REFERENCE   1  (bases 1 to 8948591)
  AUTHORS   Tang,B., Wang,Q., Yang,M., Xie,F., Zhu,Y., Zhuo,Y., Wang,S., Gao,H.,
            Ding,X., Zhang,L., Zhao,G. and Zheng,H.
  TITLE     ContigScape: a Cytoscape plugin facilitating microbial genome gap
            closing
  JOURNAL   BMC Genomics 14, 289 (2013)
   PUBMED   23627759
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8948591)
  AUTHORS   Xu,L., Zhao,W., Ge,M. and Zhao,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAR-2012) Shanghai Laiyi Center for Biopharmaceuticals
            R&D, Shanghai 201203, China
COMMENT     ##Taxonomic-Update-Statistics-START##
            This Genome (query)               :: GCA_000400635.2
            Current Name                      :: Amycolatopsis keratiniphila
            Previous Name :: Amycolatopsis orientalis HCCB10007
            Date Updated                      :: 2018-10-26
            Analysis Type :: Average Nucleotide Identity (ANI)
            Analysis 1 (A1) :: Query vs. TYPE genome for current name
            A1 Genome (subject)               :: GCA_001620365.2
            A1 Name                           :: Amycolatopsis keratiniphila
            A1 ANI                            :: 96.94781%
            A1 Query Coverage                 :: 84.86%
            A1 Subject Coverage               :: 83.93%
            Analysis 2 (A2) :: Query vs. TYPE genome for previous name
            A2 Genome (subject)               :: GCA_000478275.1
            A2 Name :: Amycolatopsis orientalis HCCB10007
            A2 ANI                            :: 90.22668%
            A2 Query Coverage                 :: 73.73%
            A2 Subject Coverage               :: 73.08%
            ##Taxonomic-Update-Statistics-END##
            ##Assembly-Data-START##
            Assembly Method                   :: Newbler v. v2.5
            Sequencing Technology :: Sanger dideoxy sequencing; 454; Illumina
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000400635.2-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 02:04:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,307
            CDSs (total)                      :: 8,242
            Genes (coding)                    :: 8,193
            CDSs (with protein)               :: 8,193
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 33 of 49
            Pseudo Genes (internal stop)      :: 3 of 49
            Pseudo Genes (multiple problems)  :: 1 of 49
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:56:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8214273
            Orig. end                         :: 8236421
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003410.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Shanghai Laiyi Center for
            Biopharmaceuticals R&D, Shanghai 201203, P.R. China,
            hccbred@gmail.com.
            The organism was changed from 'Amycolatopsis orientalis HCCB10007'
            to 'Amycolatopsis keratiniphila' in October 2018.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22148
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="30"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22148
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22148
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12148](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12148)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(339..354)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.96"
                     /tool="antismash"
     misc_feature    complement(340..354)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.76"
                     /tool="antismash"
     gene            450..1322
                     /locus_tag="AORI_RS78050"
                     /old_locus_tag="AORI_7407"
     CDS             450..1322
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337671.1"
                     /locus_tag="AORI_RS78050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7407"
                     /product="hypothetical protein"
                     /protein_id="WP_016337671.1"
                     /transl_table=11
                     /translation="MPMTLIKGTFQLVGASPDGDSVRFYPEDPQATKKAGLKVRLNSRG
                     GMQLRLDAIDALETHYQARGTGGMWHQPAEFADAAAANLLKCLGFKTVERDERGTVTSS
                     TPIKVAGHILTRFADKYGRAVAFAFPGQRPGRSADLSKVHLDVKTLKNSANYRQVADGL
                     VYPTFYSLLYPDLRDALAEAAVKARQNGLGLWPQDVTNSGFKLASRRQLADELVILPKL
                     FRRLVDYLALDESGGVSLTGFSDFLDSRNDRLFTVPDGHATEFETLVSVKRQTVSLTVE
                     PERIVFIEA"
     misc_feature    456..469
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            1444..1839
                     /locus_tag="AORI_RS78055"
                     /old_locus_tag="AORI_7408"
     CDS             1444..1839
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033480.1"
                     /locus_tag="AORI_RS78055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7408"
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_043849216.1"
                     /transl_table=11
                     /translation="METTAKLVDAVRVLVVRYCRARIGRRSGTYDIADAIAKDSCREIV
                     AGSAGARALLAFAYDVTHGLVDDFHRTTAELPNPLSGLPGQQREIMVLRSLVGLSADDT
                     ALALGCSVQAVRLGQHRALTALRPARA"
     gene            complement(1896..3170)
                     /locus_tag="AORI_RS78060"
                     /old_locus_tag="AORI_7409"
     CDS             complement(1896..3170)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631956.1"
                     /locus_tag="AORI_RS78060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7409"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_016337673.1"
                     /transl_table=11
                     /translation="MVGVTATTDSRSAIDAVWRIESARLIAGLARMTRDVGLAEELAQD
                     ALVAALEQWPESGVPRNPGAWLMTTAKRRAVDTFRRNERYEKKLGEIGREQEYEEEPDF
                     TAGLDDHIEDDLLRLVFTACHPVLSTEARVALTLKMIGGLQTHEIARAFLAKETAIAQR
                     IVRAKKTLGDAKVPFEVPEGADRVARLSSVLEVIYLIFNEGYSATAGEDWMRPALCEEA
                     LRLGRILAGLMPKEPEVHGLVALMEIQASRSAARVGPNGEPVLLMDQDRTKWNRLLIGR
                     GLAALELSESLTGGAFGVYAAQAAIAACHARARTGEETDWARIAVLYEGLGKLNPSPVI
                     ELNRAVALSMAVGPEAGLEIVDKLTSEPALKSYHLLPSVRGDFLSKLGRLDEARAEFER
                     AAEMTGNDRERTLLLNRAAECTPRD"
     gene            complement(3201..3617)
                     /locus_tag="AORI_RS78065"
                     /old_locus_tag="AORI_7410"
     CDS             complement(3201..3617)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337674.1"
                     /locus_tag="AORI_RS78065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7410"
                     /product="YciI family protein"
                     /protein_id="WP_016337674.1"
                     /transl_table=11
                     /translation="MRFMVIVKSDEKTDVAGAQPSAEELQEMGKFNEELVKAGVMLAGE
                     GLLPSSEGFRLQYSGTTEARVVDGPFAESKELIAGFWILQVKDRAEVIEWMKRAPFREG
                     EIEIRRIAEMEDFDNATPEIVEHEQNLRKQAEAN"
     gene            3751..4758
                     /locus_tag="AORI_RS78070"
                     /old_locus_tag="AORI_7411"
     CDS             3751..4758
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337675.1"
                     /locus_tag="AORI_RS78070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7411"
                     /product="small ribosomal subunit Rsm22 family protein"
                     /protein_id="WP_016337675.1"
                     /transl_table=11
                     /translation="MRESPIVPGLPDALRSALDEELGKYPQNRLTQSVERLSTRYRENA
                     PASAPILSSEADVAAYAGYRMPATYAAVHAVLAEAALRAPGFAPRTQIDIGGGTGAAIW
                     AAADVWPSLEESTVVEQVPGAIALGRRLAENAGDKAVRGSTWRRGLIDPAAPAPEADLV
                     TLSYVLGELPDARRADTVRWLSAKTSMLVLIEPGTPAGYERIVAARDQLVELGLSLVAP
                     CPHEDACPIPRGKDWCHFSARLPRTGLHRQLKSGTLGFEDEKFSYVVASRTAPDRADAR
                     VLRHPAKRKGMVSLSLCAESGLTEKIVTKRHGPAYRAARDAEWGDAWPDHSTVD"
     gene            complement(4740..5654)
                     /locus_tag="AORI_RS78075"
                     /old_locus_tag="AORI_7412"
     CDS             complement(4740..5654)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165203.1"
                     /locus_tag="AORI_RS78075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7412"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_016337676.1"
                     /transl_table=11
                     /translation="MFSLEQLVSFVAVAEELHYGRAAERLSMTQPPLSRRIQLLERELG
                     AELFDRAHRTVRLTPAGRVFLAEARKILRSSHEATLYVRRVKKGEVGVVTLGFTATAAY
                     SYLDRVIAAANAEVPGVDLVLREMGTAAQVEELLAGGIDLGMIRPPVAGADIVTLPLWR
                     EPLLAALPSAHPLARRKKNPDVRDFDGKPFIMYSPSEGRYFHDLLVAVFRAARVTPEYT
                     QYPCQVHTVLALVKAELGIALVPAAAGTLRFEGVVLRPVDGVEGRPVELDLMWRRGNDN
                     PALGALLTAIGNPARRGRQSTVE"
     gene            complement(5707..6420)
                     /locus_tag="AORI_RS78080"
                     /old_locus_tag="AORI_7413"
     CDS             complement(5707..6420)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165205.1"
                     /locus_tag="AORI_RS78080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7413"
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_016337677.1"
                     /transl_table=11
                     /translation="MTDLAADLRETFVQLADTLADDFDLVEYLDVLAFRCVELLGVCTA
                     GLLLTDPRGRLTMVAASDEKTRLLELFQSQNSEGPCLDCYRDVEPMVCPDLVRARGRWP
                     KFAREAENAGFRSVYALPMRLREEVIGALNLFGTRPAVLDDEKLRLGQALADVATIGIL
                     HHRLLQRQEIVTAQLQTALNSRVIIEQAKGVLAERLHVSVSDAFGVLRAYARSNNRKIV
                     AVAAGIIDRTVEIPR"
     gene            complement(6450..7169)
                     /locus_tag="AORI_RS78085"
                     /old_locus_tag="AORI_7414"
     CDS             complement(6450..7169)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165207.1"
                     /locus_tag="AORI_RS78085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7414"
                     /product="ANTAR domain-containing protein"
                     /protein_id="WP_016337678.1"
                     /transl_table=11
                     /translation="MTFRRHDRAAQVWSKMRFLASETDSVVTVEHACVVCGEMLEAAGA
                     GLTLATGTSLPEPVFATDARSRELEELQFTLGEGPALDVSRGGMLVVVTDVTSSEATLR
                     WPMFAPEAIDNGVKSIIAVPIQVGAITLGAVDCYREFAGLPSREGLAKALVCAEAVITL
                     ALADTGEPVLGELIDREFTEHRARVHQAAGVVSAQLEIGLPDALARLRAYAYLNDRKLD
                     EVAEDVVRHRVTFRPES"
     gene            complement(7524..8144)
                     /locus_tag="AORI_RS78090"
                     /old_locus_tag="AORI_7415"
     CDS             complement(7524..8144)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337679.1"
                     /locus_tag="AORI_RS78090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7415"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_016337679.1"
                     /transl_table=11
                     /translation="MSDGFPMRRTGGGETWISAAGWDGLAKAAADGEPHGMDDLMSAVA
                     AWARQYAETRLGGHELTYLEPADVAQEICLAVLVAVPGYGLRGGSFLFLLRAIAANKVA
                     DVFRKAARSRQVLTGELPERPAGPADEPEQRALRTDLGVRLGRLMRMLPVSHREVLGMR
                     VIGELTSNETAAALGTTSSRVRVTKHRAISRLRACAQRQDALS"
     misc_feature    8292..8307
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 21.04"
                     /tool="antismash"
     gene            8450..9637
                     /locus_tag="AORI_RS78095"
                     /old_locus_tag="AORI_7416"
     CDS             8450..9637
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165211.1"
                     /locus_tag="AORI_RS78095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7416"
                     /product="beta-1,3-glucanase family protein"
                     /protein_id="WP_016337680.1"
                     /transl_table=11
                     /translation="MRIRKKVRRVLTALAVTLPLVTGVSALSSSTAVAAGPDPLPLTVT
                     NNSNRSDAVHLYVLGTNLNTGKLGYVNAAGAFTPWPPGANPPSPAPDVSIAGPGNGGST
                     TLRIPRMLSGRVYLSFGQKIKFFLTPDGLVQPAPWADGDPNRDILFDWSEFTYDNGGLF
                     INSSQVDMFSVPHAVGLTNGAGASKEAGRLKPGGRESIFNAVQGQSGFSNLVYNRLRVL
                     APGKGLDTGKFSGSYLDGYVTSAWNTYKSTPLTVVPFEAEPGKKFTGRTGGDDVLRFTD
                     ASGATVASFSKPSTRDVFNCDGRLHAPNDQVVGPIARTLCAALHRSTLGSLHTQPTYDA
                     GQFYKQSVTDHYSRIVHEQMVDGKAYGFAFDDVGHFESLVHDGDPRTARITLTAF"
     gene            complement(10001..12148)
                     /locus_tag="AORI_RS78100"
                     /old_locus_tag="AORI_7417"
     CDS             complement(10001..12148)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033489.1"
                     /locus_tag="AORI_RS78100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7417"
                     /product="terpene cyclase"
                     /protein_id="WP_016337681.1"
                     /sec_met_domain="T1TS (E-value: 4.4e-78, bitscore: 262.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAFTLPEFYVPYPARMNPHLEAARAHSMAWAREMGMLDSPSPSG
                     DVVWTEQALAKMDYALLCAHTHPDCDGSSLDLVTDWYVWVFFFDDDFLAQFKYTRNTEG
                     AKAYLDRLELFMTGPGERSPEPRNPAEAGLENLWARTIPAMSEAWRRRFVTSTHNLMVE
                     SLWELDNIDRGRIANPIEYVQMRRRVGGAPWSANLIEFAVGAEVPDRIAATRPMEVLRD
                     TFADAVHLRNDLFSYQREVREEGENSNAVLVFEKFLDCPTQEAAELTNDLLTSRLQQFE
                     NTALVEVPALLAERDVSLSEQIAVGLYVKGLQDWQSGGHEWHTRSSRYMNEGADSGADG
                     LGLGRRVRQQAPPPFAKTGHLPLPEFRMPYPVRTSPHLAAAREYAPGWAREMGMLESGV
                     WDERRFRGIDLAHCAAMIDPDADLDGLKLSTDWLTWGTYGDDYFPLVFGAKRDAVAAKL
                     CSDRLSLFMPLEGEPVPKPSNPIEVGLVDLWGRTAGPLSPHARAGFRLAVESMTASWAW
                     EVGNQAQNRVPDPVDYVEMRRRTFGSDLTKSLALLELGDVVPAELFGNRVLFELDTAAQ
                     DYAAFSNDLFSYQKEIEYEGEVHNLVYVAERFLEVDRIEARDIAARLMNARMTQFEQLA
                     DEDLPRMCDDLGLGDDVRAAVTGYADHLKDWMAGILEWHRKCVRYTPEELARVHAPEPP
                     AFSLVPSGIGMSAWRIGSGAR"
     gene            complement(12254..13033)
                     /locus_tag="AORI_RS78105"
                     /old_locus_tag="AORI_7418"
     CDS             complement(12254..13033)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033490.1"
                     /locus_tag="AORI_RS78105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7418"
                     /product="DUF3800 domain-containing protein"
                     /protein_id="WP_016337682.1"
                     /transl_table=11
                     /translation="MRSVPLEIACDESGSEGEKLIGGRTGVFAHAGVRLSLEEAAACLA
                     ELRRRIRSPAVEYKANHLLRTKHRRVLEWFLGPLGPVHGRARVYLVDKKRLLANELRAL
                     AGPGIRPDDELLAAFNDVLRTRNRREPSAGSFFAMAGDTAELRAKVSRARDANALDPLV
                     PAILRAIEYWSAGGEPVFLVHDEQPSLKGDRLARIEASPGLAGVKFVDSRTDPRVQAAD
                     FLVGAARRIAEDELTGNGDAILTGLLAPYVDPESIWD"
     gene            complement(13066..13857)
                     /locus_tag="AORI_RS78110"
                     /old_locus_tag="AORI_7419"
     CDS             complement(13066..13857)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337683.1"
                     /locus_tag="AORI_RS78110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7419"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_016337683.1"
                     /transl_table=11
                     /translation="MDEVFKALADPSRRRLLDDLNARNGQTLRELCAGLDMARQSVSKH
                     LAVLEAANLVTTVWRGREKLHYVNAEPINAIAERWIDRYHQGRVDALADLKKALEQEPM
                     STDEFVYTSYIRTTPERLWRALTDPVFTKQYWGCEFTSDWKAGSTMAWEQLGVKLEDPE
                     QVVLESDPYRRLSYTWHTFTPEFAKSVGLDDDVSAKLRAESRSKVTFDLEPVGDTVKLT
                     VVHDGFDPGSTALEMVKGGWPSILSSLKSLLETGEPLPEPA"
     gene            13993..14367
                     /locus_tag="AORI_RS78115"
                     /old_locus_tag="AORI_7420"
     CDS             13993..14367
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020634126.1"
                     /locus_tag="AORI_RS78115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7420"
                     /product="hypothetical protein"
                     /protein_id="WP_016337684.1"
                     /transl_table=11
                     /translation="MPTPLRVAIAVQTLAVFLTPISAGLLLTVPSGHTLHSATAYTLFV
                     VATLHVLIAILVWRPGGGSAKPILPAAVFLGLTLVQVFLGIAHATAVHVPLGVLLFGFS
                     LVQLSRIRPLPREAAVTAAP"
     misc_feature    14413..14424
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    14473..14488
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 23.65"
                     /tool="antismash"
     misc_feature    complement(14473..14489)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 24.31"
                     /tool="antismash"
     gene            14492..15385
                     /locus_tag="AORI_RS78120"
                     /old_locus_tag="AORI_7421"
     CDS             14492..15385
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223310.1"
                     /locus_tag="AORI_RS78120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7421"
                     /product="TIGR03619 family F420-dependent LLM class
                     oxidoreductase"
                     /protein_id="WP_016337685.1"
                     /transl_table=11
                     /translation="MRLGFSLPVFGKAAATPGGIARYARTAEQAGAASLWVGDRLLSPV
                     NPEVAYPGYDTMPEEFWTAQDPFTALAVAAAVTETAILGSSTINATQYQPANFARLLTS
                     IDVASNGRLLPGLGIGWSPDEYAAVGVPMAERGKRLDDLLDLLDTWWTKDTVSHNGIGY
                     TIPETHVHLKPVRKPPVHLAGFGERALRRVAERADGWLPVWTVPETIPADMLTSTLAKI
                     RADAEQAGRDPRTLGVALRVNAAPDTKPELIAESVTKIVATLAPDHTFVDLTYLTSSVE
                     EHIDLTGRLLELTARG"
     tRNA            complement(15478..15550)
                     /anticodon=(pos:complement(8229788..8229790),aa:Thr,
                     seq:tgt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="AORI_RS78125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="AORI_R057"
                     /product="tRNA-Thr"
     gene            complement(15478..15550)
                     /locus_tag="AORI_RS78125"
                     /old_locus_tag="AORI_R057"
     gene            complement(15797..15943)
                     /locus_tag="AORI_RS84500"
     CDS             complement(15797..15943)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AORI_RS84500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_228688258.1"
                     /transl_table=11
                     /translation="MGRRRVLDTIAPWANDVPRDAASVAVEFVYPSVTSDNIDEASRRG
                     PAR"
     gene            complement(16025..16828)
                     /locus_tag="AORI_RS82315"
                     /old_locus_tag="AORI_7422"
     CDS             complement(16025..16828)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020976.4"
                     /locus_tag="AORI_RS82315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7422"
                     /product="alkaline phosphatase D family protein"
                     /protein_id="WP_228688259.1"
                     /transl_table=11
                     /translation="MTSAVSRRSVLRAVGVTAAGTAATFTLSGVSNGAEAPVFAHGVAS
                     GDPMPDSVLLWTRVTPSPEAVPGSGKGAAVAADAGFARVVARGHLRTGPERDHTVKVTA
                     GGLRAATGYWYRFTSQGKVSQTGRTRTAPSRDEDVESLRFGVVSCANWAVGHFAPYGYL
                     SGRDDLDAFIHLGDYLYEGSPNPAGDLRPSVPPNELITLADYRQRHAMYKTDEHLRRLH
                     ARHPMIATWDDHEVADNAWSGGSPSHHPATEGDWAASRAGPRPGT"
     gene            16978..18543
                     /locus_tag="AORI_RS78135"
                     /old_locus_tag="AORI_7423"
     CDS             16978..18543
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337687.1"
                     /locus_tag="AORI_RS78135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7423"
                     /product="threonine/serine exporter family protein"
                     /protein_id="WP_016337687.1"
                     /transl_table=11
                     /translation="MKINEHTTGAKRGERGVEKNQDETPERGEWLLEAPRQRDGERSIP
                     QTRSHRPNLLRRRAWQILEAPTAEQPAVDVDEAMGPQPPDDTTVNFVLDLVLRIGEVQM
                     SSGAGASDVTATIIALTSALGLPHCEVDVIFTSITVTCHRGTDMAPVTALRVVRSRSLD
                     YTRLTQTETLVRRIVRGNIGAEEAQQELQRITTAPHPYPRWVATAAWGGLAAFITLILG
                     GSIDVALVALVISAVIDRLGRFLNRFALPFFFQQVIGGLVATLSAMAIVSSNLLTTDKP
                     TLVVAAAVTVLLSGLSTVSAVQDAITGYYVTAAGRTTETALMSAGLIAGVVLALKIAVL
                     LGLPLTPLPEVVSSTPQQLPIIVIGSVGASACFALASYSTLRAMIVAGAAGAIGGAVYG
                     ALMLTDFQAVSSSAVAATLVGFCGGVLARRLKVTPLVVAVSGITPLLPGLSTYRGLYQL
                     GVEPGGNISTLMTAVAIGLALAAGVVLGEYLAQPVRTGLGRLERKFAGPRMAGPLEPAE
                     RRLE"
     gene            18625..20076
                     /locus_tag="AORI_RS78140"
                     /old_locus_tag="AORI_7424"
     CDS             18625..20076
                     /EC_number="2.4.1.15"
                     /GO_function="GO:0003825 - alpha,alpha-trehalose-phosphate
                     synthase (UDP-forming) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631981.1"
                     /locus_tag="AORI_RS78140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_7424"
                     /product="trehalose-6-phosphate synthase"
                     /protein_id="WP_016337688.1"
                     /transl_table=11
                     /translation="MDEVIAETSRTASADFVVVANRLPVDLERTADGSRRWTASPGGLV
                     SALEPFLRSRKGAWVGWPGVPDVDVEEFDDDGLVLHPVSLTSDDVRDYYEGFSNATLWP
                     LYHDVVARPVFDRSWWESYVRVNRRFAEASAKVAAEGATVWIQDYQLQLVPAMLRELRP
                     DLRIGFFLHIPFPPVELFMQMPWRTEIVRGLVGADLVGFHRPGGAQNFLWLARQLAGLE
                     SSRGAVGIRTRPGLMQVGDRTVRVGAFPISIDAIGLDKLAKTKGVAERAAQLRRDLGNP
                     KKVLLGVDRLDYTKGIDLRLQALHELLHEGRVRPEDVTFVQLATPSRERVEHYQRMRGD
                     IEQMVGRINGEFARVGHPVVHYLHQSVNRTELAAFFSAADVMVVTPLRDGMNLVCKEYV
                     ACRHDLGGSLVLSEFAGAAAELTSALLVNPHDLDGVKNALETAITLDPAEGRRRMRAMR
                     RQVLTHDVDRWARSFLQALGAEPAD"
     misc_feature    20106..20117
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.22"
                     /tool="antismash"
     misc_feature    complement(20648..20663)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.88"
                     /tool="antismash"
     misc_feature    20927..20940
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(20927..20940)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.17"
                     /tool="antismash"
     misc_feature    complement(20931..20944)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.97"
                     /tool="antismash"
     misc_feature    complement(22010..22024)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
ORIGIN
        1 gtgctgttcc cgttgttctc cgcctacatc ggctggctgg gtgtcttcct caccggctcg
       61 gacgcgtcga cgaacagtct cttcgggccg atgcaggtga tttcggcgca gcagctgcac
      121 gtcgacccga tcctcgccgg cgccaccaac acctccggcg gcgtgatggg caagatgatc
      181 tcgccgcaga acctgtccat cggcgccacc gcgatcggcc agtccgggaa ggaaggcgcg
      241 ctgctgcggc agaccttcct gtggtcggtg gtgctgaccg ccgtggtcgg ggtgatctcg
      301 ttgctccagg cgacggtgct gcggttcatg atcccgtcgt gaacgtgaat tcgagaatgt
      361 ccacaatggt catccgatct taaccggcca ttgggctgga tggatgaaca ccggatccgt
      421 tcaccggaat gggaactacc gttgtcccca tgcccatgac gctgatcaaa ggtacgttcc
      481 agcttgtcgg agcctcaccg gacggcgatt cggtgcggtt ctatcccgaa gacccgcagg
      541 cgaccaagaa ggcgggcctg aaggtccggc tcaattcgcg gggcgggatg cagttgcggc
      601 tcgacgcgat cgacgcgctc gaaacgcatt accaggccag gggaaccggc gggatgtggc
      661 accagcccgc ggaattcgcc gacgccgccg cggcgaacct gctgaagtgc ctcggcttca
      721 aaacggtcga acgcgacgag cggggaacgg tcacttcgtc gaccccgatc aaggtagccg
      781 gtcacatact gacgcgattc gccgacaaat acggacgagc cgtcgcgttc gcctttcccg
      841 ggcaacggcc gggacggtcg gcggaccttt ccaaggtcca tctcgacgtc aaaacgctga
      901 agaactccgc gaactaccgg caggtcgcgg acggcctcgt ctacccgacg ttctattcac
      961 tgctttaccc cgatctccgt gacgccttgg ccgaagccgc ggtgaaagcc cgccagaacg
     1021 ggctcgggct gtggccgcag gacgtcacga actccgggtt caagctcgcg tcgcggcggc
     1081 agctcgccga cgaactggtg atcctgccga aactgttccg acggctcgtc gactacctcg
     1141 cgctcgacga aagcggcggc gtctcgctga ccggcttctc cgacttcctc gattcccgca
     1201 acgaccgcct gttcaccgtc ccggacgggc acgcgacgga attcgagacc ttggtgagcg
     1261 tgaagcggca gaccgtgagc ctgacggtcg agccggagcg gatcgtcttc atcgaggcct
     1321 gacccacccg tgtgggcaaa aagaccgtac ctccctcccc cgcggccgtg ctcatctgaa
     1381 aggtgggaga gggagccgat ggaaggacac ggttcacgac ggccggagga ggccggcggg
     1441 cggatggaga cgactgcgaa actcgtcgac gccgtccgcg tcctggtcgt gcgttactgc
     1501 cgggcgcgga tcggccgtcg gtcgggcacc tacgacatcg ccgacgcgat cgccaaggac
     1561 agctgccgcg agatcgtcgc cggttcggcc ggggcgcgcg ccctgctcgc gttcgcctac
     1621 gacgtcacgc acggtctggt cgacgacttc caccggacca ccgccgaact gccgaacccg
     1681 ctttccgggc tgccgggcca gcagcgcgag atcatggtgc tgcggtcgct cgtcgggctt
     1741 tccgccgacg acaccgcgct cgcgctcggc tgttccgtcc aggcggtccg gctggggcag
     1801 caccgtgcgc tgaccgcgct tcgccctgcc cgcgcctgac gcgtttcgtc ctctgaatgc
     1861 gctggttcgc gccacgaacc accgcattca gaggactaat cgcgaggggt gcattcggcg
     1921 gcgcggttca ggagcagggt gcgctcccgg tcgttgccgg tcatctccgc cgcccgctcg
     1981 aactcggcgc gggcctcgtc gaggcggccg agcttcgaca ggaagtcgcc gcgcacgctc
     2041 ggcagcaggt gatacgactt gagcgcgggc tccgacgtca gcttgtcgac gatctccagc
     2101 cccgcctccg gccccacggc catcgacagc gccaccgcgc ggttcagttc gatcaccggc
     2161 gacgggttca gcttcccgag gccttcgtac aggacggcga tgcgcgccca gtcggtctcc
     2221 tcacccgtcc gcgcccgcgc gtggcaggcg gcgatggcgg cctgcgccgc gtagacgccg
     2281 aaagcgccgc ccgtgagcga ctcggaaagt tccagcgcgg cgaggccgcg gccgatcagg
     2341 agccggttcc acttcgtccg gtcctgatcc atcagcaaca caggctcgcc gttcggcccg
     2401 acacgggcgg cggaccgcga agcctggatc tccatcagcg cgacgagccc gtgcacctcg
     2461 ggttccttcg gcatcagccc ggcgaggatc cgtccgagcc gcagcgcctc ctcgcacagc
     2521 gcaggccgca tccagtcctc gcccgccgtt gccgagtacc cctcgttgaa gatcagatag
     2581 atgacttcca gcaccgaaga aaggcgcgcg accctgtccg cgccctcggg cacctcgaac
     2641 ggcaccttgg cgtcgccgag cgtcttcttc gcgcgcacga tccgctgcgc gatggcggtc
     2701 tccttggcca ggaacgcccg cgcgatctcg tgcgtctgca acccgccgat catcttcagc
     2761 gtcagcgcga ccctggcctc ggtcgagagc accgggtggc aggcggtgaa caccagccgc
     2821 agcagatcgt cctcgatgtg gtcgtcgagg cccgcggtga agtcgggttc ctcctcgtac
     2881 tcctgctcgc ggccgatctc gccgagcttc ttctcgtagc gctcgttgcg ccggaaggtg
     2941 tcgaccgccc ggcgtttggc cgtggtcatg agccaggcgc ccggattcct cgggacgccc
     3001 gactcaggcc actgttcgag cgcggcgacc agcgcgtcct gcgccagctc ctccgcgagg
     3061 ccgacgtcgc gcgtcatccg cgcgaggccg gcgatgaggc gggccgattc gatccgccac
     3121 accgcgtcga tcgccgaacg ggagtctgtc gttgccgtca cgccgaccaa tcaacatcgt
     3181 cggcgcgacg accgcaacca ctagttggcc tcggcctgct tccgcaggtt ctgctcgtgc
     3241 tcgacgatct cgggggtcgc gttgtcgaag tcctccatct ccgcgatccg gcggatctcg
     3301 atctcgccct cgcggaacgg cgcgcgcttc atccattcga tgacctcggc gcggtccttg
     3361 acctgcagga tccagaaacc ggcgatgagt tccttgctct cggcgaacgg cccgtcgacg
     3421 acgcgcgcct cggtggtgcc ggagtactgg aggcggaaac cctcggagct ggggagcagg
     3481 ccttcacccg cgagcatgac gccggccttc accagctcct cgttgaactt ccccatctcc
     3541 tgcagctcct cggcgctcgg ctgcgcgccg gccacgtcgg tcttctcgtc gctcttgaca
     3601 atcaccatga accgcatcga agtctccgtt cccggcgggg ctcgtccctg ccacatctac
     3661 gcgtcgatcg ggcaccccag gtttcgacac ggtccccgaa cttttttccg cggatattcg
     3721 agcagccgga aaaccgcagg tcaaccaccc atgagagaat ctccgatcgt gcctggactc
     3781 cccgacgccc tccgctccgc cctcgacgaa gagctgggca agtacccgca gaacaggctg
     3841 acgcagtccg tcgagcggct cagcacgcgc taccgcgaga acgcccccgc gagcgcgccc
     3901 atcctctcgt ccgaagcgga cgtcgcggcg tacgcgggct accggatgcc ggccacgtac
     3961 gcggctgtcc acgccgtcct cgccgaagcc gcccttcgcg cgcctgggtt cgctccgcgt
     4021 acacagatcg acatcggcgg cggaaccggt gccgcgatct gggcggcggc cgacgtgtgg
     4081 ccgtcactgg aggagagcac cgtcgtcgag caggtgcccg gcgcgatcgc gctggggcgg
     4141 cggctcgcgg agaacgccgg ggacaaggcc gtccgggggt cgacctggcg gcgcggcctg
     4201 atcgacccgg cggcgcccgc acccgaggcc gatctggtga ccctttccta tgtcctcggc
     4261 gagctgcccg atgcccgccg ggccgacacc gtccgctggc tttcggcgaa gacctcgatg
     4321 ctggtgctga tcgaacccgg cacccccgcg ggttacgagc ggatcgtcgc ggcgcgggat
     4381 cagctcgtcg aactcgggct ctccctggtc gcgccctgtc cgcacgagga cgcctgcccg
     4441 atcccgcgcg gcaaggactg gtgccatttc tccgcgcgcc tcccgcgcac cggcctgcac
     4501 cgtcagctca agtccggaac gctcggcttc gaggacgaga agttctccta cgtcgtcgcc
     4561 tcccgcacgg cgccggaccg cgccgacgcc cgcgtcctgc ggcatccggc caaacgcaag
     4621 ggcatggtca gcctgtccct gtgcgccgaa tcagggctca ccgaaaagat cgtcaccaaa
     4681 cggcacggcc cggcctaccg cgccgcccgc gacgcggaat ggggcgacgc ctggcccgat
     4741 cactccacag tggactgacg gccgcgccgc gccgggttgc cgatggcggt gagcagcgcg
     4801 ccgagcgccg gattgtcgtt gccccgccgc cacatcaggt cgagttccac cggacggccc
     4861 tcgacaccgt ccactggacg gagaacgaca ccttcgaagc gcagcgtgcc cgccgcggcg
     4921 ggcaccagcg cgatcccgag ctccgccttc accagcgcga gcaccgtatg cacctggcag
     4981 gggtattgcg tgtactccgg cgtcacccgg gcggcgcgga acaccgccac gagcagatcg
     5041 tggaagtacc ggccttccga cggcgaatac atgatgaacg gtttgccgtc gaaatcgcgg
     5101 acgtcgggat tcttcttgcg ccgggccaaa ggatgcgccg acggcagcgc cgccagcagc
     5161 ggttcccgcc acagcggcag ggtcacgatg tcggcgccgg cgaccggcgg ccggatcatg
     5221 ccgaggtcga tcccgcccgc cagcagctcc tccacctgcg ccgccgtccc catctcccgg
     5281 agcacgagat cgacgccggg cacctcggcg ttcgccgcgg cgatgacccg gtcgagatac
     5341 gaatacgccg ccgtggcggt gaacccgagc gtcacgacgc cgacctcgcc cttcttcacg
     5401 cggcggacgt acaacgtcgc ttcgtgtgac gagcgcagga tcttccttgc ctcggcgagg
     5461 aaaacccgtc cggcgggggt cagccggacc gtgcggtgcg cccggtcgaa aagctcggca
     5521 cccagttcgc gctccagcag ctggatccgc ctgctcaacg gcggctgggt catcgagagc
     5581 cgctccgccg cccggccgta gtgcagttcc tcggccaccg cgacgaaact caccagctgc
     5641 tccagggaga acacccatcc agtctaggaa tcggcaaggg gcggacaagc gccgaaccgg
     5701 tatcgctcag cgcgggattt ccaccgtgcg gtcgatgatc ccggccgcca ccgcgacgat
     5761 cttgcgattg ttgctccgcg cgtaggcgcg caatacgccg aacgcgtcgc tcaccgaaac
     5821 gtggagccgt tcggccagca cacctttcgc ctgctcgatg atcacccggc tgttcaacgc
     5881 cgtttgcagc tgcgcggtga cgatctcctg ccgctgcagc aaccggtgat gcaggatgcc
     5941 gatcgtggcg acgtccgcga gtgcctgccc cagccgcaat ttctcgtcgt cgagcacggc
     6001 ggggcgggtg ccgaacaggt tcagcgcgcc gatcacctct tcccgcaacc gcatcggcaa
     6061 cgcgtacacg gaacggaatc cggcgttttc cgcctcccgt gcgaacttcg gccatcttcc
     6121 gcgcgcacgc acgagatccg ggcagaccat cggctcgacg tcccggtagc agtccaggca
     6181 cggtccttcg gagttctgcg actggaacag ttcgagcaac cgggtttttt cgtcggaagc
     6241 ggccaccatg gtgagcctgc cccgcgggtc ggtgagcaac aggcccgcgg tgcagacgcc
     6301 gagcagctcg acacatctga acgcgagcac gtcgaggtat tcgacgagat cgaagtcgtc
     6361 cgccagggtg tcggccagct gcacgaaggt ttccctcagg tcggccgcca ggtcggtcat
     6421 ctttccgctg tctccttatc gcacatccgt catgactcgg gccggaacgt gacccggtgc
     6481 cgcaccacgt cctcggcgac ctcgtcgagc ttccggtcgt tgaggtaggc gtaggcgcgc
     6541 aggcgggcga gcgcgtccgg aagcccgatt tcgagctggg ccgacaccac gcccgcggcc
     6601 tgatgcaccc gggcgcggtg ttcggtgaat tcacgatcga tcaattcgcc gagaaccggt
     6661 tcaccggtat cggccaaggc cagggtgatg accgcttccg cacagacgag cgccttcgcc
     6721 aggccctccc gcgaagggag cccggcgaat tcgcgataac agtccaccgc acccaaagtg
     6781 atggcaccga cctgaatcgg caccgcgatg atcgatttca cgccgttgtc gatcgcctcg
     6841 ggcgcgaaca tcggccatcg gagtgtcgcc tccgaactgg tcacatcggt tacgacgacg
     6901 agcataccgc cgcgggaaac gtccaatgcc ggtccttcac ccaaggtgaa ctgcagctct
     6961 tccaattcac ggctgcgcgc atcggtggcg aagaccggct ccggcaaact cgtcccggtg
     7021 gcgagcgtga gcccggcgcc ggccgcctcg agcatttccc cgcagacgac acaggcatgt
     7081 tccaccgtca ccaccgaatc ggtttccgaa gcgaggaaac gcatcttcga ccagacctgc
     7141 gcggcgcgat catgtcgccg gaacgtcatg gcatgcctcc cgggcgtgtc cggattcgga
     7201 caggaccgcc gggggccgga gcgaacagag cgctcgcgcg ccacgatcat cctcgcacgg
     7261 tttcggctct ttgccgcgct ttcagtgact tatcggcacc aatgcagtag cccgaagagc
     7321 cgaatggccg gtccggatgg cggtcaatgg tccgttcagc cggttccggc tccccggacc
     7381 gggcctaggg tggaagccga gaccgttcgc tccggccctc ggcgatcgtg ctcgacggcg
     7441 agctctggag gggccatgtg cgttcgcatt ctcgaaaccc gtgccaaacg ggagaatccg
     7501 ttgttccggc tgctgatccg tattcagctc aaggcgtcct ggcgctgagc gcaggcccgc
     7561 agcctgctga tcgcgcggtg tttggtcacc cgcacccgtg acgacgtcgt accgagcgcc
     7621 gccgcggtct cgttcgacgt cagctcgccg atcacccgca tccccagtac ctcacggtgg
     7681 gagacgggca gcatccgcat cagcctgccg agccggaccc cgaggtcggt ccgcagcgcg
     7741 cgctgctcgg gttcgtcggc gggccccgcc ggccgttcgg ggagttcgcc ggtgagcact
     7801 tgcctgctcc gcgccgcctt gcggaagacg tcggcgacct tgttcgccgc gatggcgcgc
     7861 aggaggaaca ggaacgaacc gccgcgcagg ccgtatccgg ggacggcgac cagcacggcg
     7921 aggcagatct cctgtgccac gtcggccggt tcgaggtagg tcagctcgtg gccgccaagg
     7981 cgggtctcgg cgtactgccg tgcccacgcc gcgacggcgg acatgaggtc gtccatgccg
     8041 tgcggctcac cgtccgccgc ggccttggcg aggccgtccc agccggcggc ggaaatccac
     8101 gtctcgccgc cgccggttct tcgcatcgga aatccgtcgc tcatgtcccg ctccccacgg
     8161 atgagaaaac ccggccgccg gggtccagga cggaacccgg acaacggtag tcgacgaatc
     8221 cggtcacctc aatcgacgaa gggcccgcga cgaattgtcc ggcccggcgg aaaaccggac
     8281 agattcccac caatggtctg gacatgtcgg catcccgcga cgtaacttcc cgtgctgaga
     8341 cccctcgcca aggtcacgcc aaggccggga acgcgccccc ggccgacatc cgcaagcacc
     8401 gccgcggcgc gtccacgctc cgcggcggga ttccgccgag gagtgaactg tgcgcatccg
     8461 caagaaagtc cggcgcgttt tgaccgcttt ggcggtcacc ctccccctgg tcaccggtgt
     8521 ttcggcgctt tcgtcgtcca ccgcggtcgc cgcgggcccc gatccgctgc cgctgaccgt
     8581 gacgaacaat tcgaaccgct ccgacgccgt ccacctctac gtgctcggca cgaacctcaa
     8641 caccgggaag ctcggctacg tcaatgccgc cggcgccttc acgccgtggc ctccgggcgc
     8701 gaacccgccg agccccgcgc cggacgtctc gatcgcgggc cccggcaacg gcggctcgac
     8761 cacgctgcgg atcccgcgca tgctctcggg ccgggtctac ctgtcgttcg ggcagaagat
     8821 caagttcttc ctcaccccgg acggcctggt gcagcccgcg ccgtgggccg acggcgaccc
     8881 gaaccgcgac atcctgttcg actggagcga attcacctac gacaacggcg ggctgttcat
     8941 caacagctcg caggtggaca tgttcagcgt gccgcacgcc gtcgggctga ccaacggggc
     9001 gggcgcgagc aaggaggcag gccgcttgaa gcccggtggc cgcgagagca tcttcaacgc
     9061 cgtccaaggc cagtccgggt tctcgaacct ggtgtacaac cggctgcggg tcctcgcgcc
     9121 gggcaagggg ctcgacaccg gcaagttcag cggcagctac ctcgacggtt acgtcacgag
     9181 cgcctggaac acctacaagt cgacaccgct caccgtggtc ccgttcgagg ccgaacccgg
     9241 caagaagttc accggccgga ccggcgggga cgacgtcctg cgcttcaccg acgcctcggg
     9301 cgccacggtg gcgtcgttca gcaagccgag cacccgcgac gtcttcaact gcgacggacg
     9361 gctgcacgcg ccgaacgacc aggtcgtcgg cccgatcgcg cggacgctgt gcgcggcgct
     9421 gcaccgctcg acgctcggct cgctgcacac gcagccgacg tacgacgcgg gccagttcta
     9481 caagcagtcc gtgaccgacc actactcgcg gatcgtgcac gagcagatgg tcgacgggaa
     9541 ggcgtacggc ttcgccttcg acgacgtcgg gcacttcgag tcgctggtgc acgacggaga
     9601 cccgcggacc gcgcggatca cactgaccgc gttctgacgg ttcggcctca ggcggggcgt
     9661 attcccgctt ggcatctgtc taggtgattt cgttgctgcc gtgcgtgggc tgaaggctcc
     9721 cttcaccgcg tctgatgcgg cgaaaggagc cttcagcccg atcacgggtc gggtccgcga
     9781 aggcctcctt gcctaccctg aaggtagtga aggagacctt cactaccttc agagatcgcc
     9841 accggcagct cacctgcacc agcaagcaca gcaatcacca cggtggcgcg tgaaggcccc
     9901 agtacatgaa ggcgcccaac ccggtggtcg tgagtggcgt ttcggcttag aacccgaatc
     9961 gccactcacg accggcttcc gcgacacgct cacgggcccg tcagcgcgcc ccgctcccga
    10021 tccgccaggc cgacataccg atcccgctcg gcacgagcga gaacgccggc ggctcgggag
    10081 cgtggacgcg tgccagctcc tccggcgtgt accgcacgca tttccggtgc cattccagga
    10141 ttccggccat ccagtccttc aggtggtccg cgtatccggt gaccgccgcg cggacgtcgt
    10201 cgccgagccc gaggtcgtcg cacatccgcg gcaggtcctc gtcggcgagc tgctcgaact
    10261 gcgtcatccg cgcgttcatc agccgggcgg cgatgtcgcg ggcctcgatc cggtcaacct
    10321 ccaggaaccg ctcggcgacg tacacgaggt tgtgcacctc gccctcgtat tcgatctcct
    10381 tctggtacga gaacaggtcg ttggagaagg ccgcgtaatc ctgcgccgcc gtgtcgagtt
    10441 cgaacagcac gcggttcccg aagagctcgg cgggcacgac gtcgccgagt tcgaggagcg
    10501 cgagactctt ggtgaggtcg gagccgaacg tccggcgccg catctccacg tagtcgaccg
    10561 gatcgggcac ccggttctgc gcctggttcc cgacctccca ggcccagctc gcggtcatgc
    10621 tctcgaccgc cagccggaaa cccgcgcgtg cgtgcgggga cagcggtccc gcggtgcggc
    10681 cccacaggtc cacgaggccc acctcgatcg gattcgacgg cttgggcacc ggctcacctt
    10741 cgagtggcat gaacagggaa agccggtcgc tgcacagctt cgcggcgacc gcgtcccgtt
    10801 tcgccccgaa gaccagcggg aagtagtcgt cgccgtacgt gccccaggtg agccagtcgg
    10861 tcgacagctt cagcccgtcg agatccgcgt ccggatcgat catcgcggcg cagtgcgcca
    10921 ggtcgatgcc gcgaaaccgg cgctcgtccc agaccccgct ctcgagcatc cccatctcgc
    10981 gcgcccagcc gggtgcgtat tcgcgcgccg cggcgaggtg agggctggtg cgcacggggt
    11041 acggcatgcg gaattcgggc aacggcaggt gcccggtctt cgcgaacggc ggcggcgcct
    11101 gctgccgcac ccgacggccg agacccagcc cgtcggcacc ggagtccgca ccctcgttca
    11161 tgtaccggct cgagcgggtg tgccattcgt gcccgccgga ctgccagtcc tgcaggcctt
    11221 tgacgtacag gccgaccgcg atctgctcgg acagcgagac gtcgcgctcg gcgagcaacg
    11281 cgggcacctc gacgagcgcg gtgttctcga actgctgcaa tcgcgaggtc agcaggtcat
    11341 tggtgagttc ggcggcttcc tgcgtcgggc agtcgaggaa cttctcgaag acgagcaccg
    11401 cgttggagtt ctcgccctct tcgcgcactt cgcgttggta ggaaaagaga tcgttgcgca
    11461 ggtggacggc gtcggcgaac gtgtcgcgca gcacctccat cggcctggtc gccgcgatcc
    11521 tgtccggtac ctcggcaccg acggcgaact cgatgaggtt cgccgaccac ggcgcccctc
    11581 cgacgcgacg gcgcatctgg acgtattcga tggggttcgc gatgcggccg cggtcgatgt
    11641 tgtccagttc ccagagcgat tcgaccatca ggttgtgcgt actggtgacg aaccgccgcc
    11701 gccaggcttc ggacatcgcg ggaatggtgc gcgcccaaag attctcgagc ccggcttcgg
    11761 cgggattccg cggttcgggc gacctttccc ccgggccggt catgaacagt tccaagcggt
    11821 ccaaataggc cttcgcgccc tcggtgttgc gggtgtactt gaattgcgcg aggaaatcgt
    11881 cgtcgaagaa gaacacccac acgtaccagt ccgtgaccag atcgagggac gacccgtcac
    11941 agtccggatg ggtgtgcgcg cagagcagcg cgtaatccat tttcgccagc gcctgctcgg
    12001 tccagacgac gtcaccggac ggcgatgggg aatcgagcat ccccatttcc ctggcccagg
    12061 ccatactgtg cgcccgcgcc gcttcgaggt gcggattcat cctggccgga tacggcacgt
    12121 agaactcggg caaggtgaaa gcctgcatcg gcgactgcct cccgggccgg ggtcggatcc
    12181 gttccgacgt ttccagcccg ccgccgcgcc gggcaaccgt ccacccgagc gattcggtgc
    12241 gccatggagt gaatcagtcc cagatggact ccggatcgac atacggcgcg agcaatccgg
    12301 tcaatatcgc gtcaccgttc ccggtcaatt cgtcctcggc gatccggcgg gcggcgccga
    12361 cgaggaaatc ggcggcctgc acccgcggat cggtccgtga atccacgaac ttcaccccgg
    12421 ccaatcccgg actcgcctcg atccgggcga gccggtctcc tttcagcgac ggttgttcgt
    12481 cgtggacgag gaagaccggc tcgcctcccg cgctccagta ctcgatggcg cggaggatcg
    12541 cgggcaccag cggatcgagg gcattggcgt cacgcgcccg gctgaccttc gcccgcaatt
    12601 ccgcggtgtc cccggccatc gcgaagaacg accccgccga cggctcccgg cggttcctgg
    12661 tgcgcagcac gtcgttgaac gcggcgagca gctcgtcgtc cggccggatt cccgggccgg
    12721 cgagcgcgcg gagttcgttc gccagcagcc gcttcttgtc cacgaggtac acgcgggcac
    12781 gcccgtggac cgggccgagc ggaccgagga accattcgag cacccgccgg tgcttcgtgc
    12841 ggagaaggtg gttcgccttg tactcgaccg ccggcgagcg gatcctccgc cgcagttcgg
    12901 ccaggcaggc cgcggcctct tcgaggctca gccggacccc cgcgtgcgcg aacacgccgg
    12961 tccgcccgcc gatcagtttc tcgccctcgg acccggactc gtcgcaggcg atctccaggg
    13021 gcacgctgcg catcgtgccc gatcgcgagg gcgcggtcga ccgggttacg cgggttcggg
    13081 cagcggttcg ccggtctcga gcagcgactt gaggctcgac aggatcgacg gccagccgcc
    13141 cttgaccatc tccaacgcgg tgctacccgg gtcgaaaccg tcgtgcacca cggtcagctt
    13201 caccgtgtcg ccgacgggtt cgaggtcgaa cgtcaccttc gaccgcgact cggcccgcag
    13261 cttcgccgac acgtcgtcgt cgagcccgac cgacttggcg aactccggcg tgaaggtgtg
    13321 ccaggtgtag gacagccgcc ggtacgggtc ggactcgagg acgacctgtt cgggatcctc
    13381 cagcttcacg ccgagctgct cccaggccat cgtcgacccg gccttccagt ccgaggtgaa
    13441 ctcgcaaccc cagtactgct tggtgaagac cggatcggtg agcgcccgcc aaagccgctc
    13501 cggcgtcgtc ctgatgtagc tggtgtacac gaattcgtcg gtgctcatgg gttcctgctc
    13561 caatgccttc ttgaggtcgg cgagcgcgtc gacccggccc tggtggtacc ggtcgatcca
    13621 gcgctcggcg atcgcgttga tcggctccgc gttcacgtag tgcaacttct cgcggccacg
    13681 ccacaccgtc gtcacgagat tcgccgcttc cagcacggcc agatgcttgc tgaccgactg
    13741 ccgcgccatg tccagccccg cgcacagctc gcgcagggtc tgcccgttgc gggcgttcag
    13801 gtcgtcgagc aaccggcgcc tgctcgggtc ggccagtgcc ttgaagacct cgtccatgcc
    13861 gctctccctg atatgcagcc tcgcggctgc ctttgcagat taggcagccg agcggctgca
    13921 tgtcaagcca cgcgtcacgt ttccggcggc tccctcgtcc acgtggtgac acctccacac
    13981 gaaggagttc acatgccgac cccgttgcgc gtcgcgatcg ccgtgcagac cctggccgtc
    14041 ttcctcaccc cgatctccgc cggcctcctg ctgaccgtgc cgagtggcca caccctgcac
    14101 agcgccacgg cctacacgct gttcgtcgtc gcgacgctgc acgtgctcat cgcgatcctc
    14161 gtgtggcggc cgggcggcgg ctccgccaag ccgatcctgc ccgcggccgt gttcctcggt
    14221 ctcacgctgg tgcaggtgtt cctcgggatc gcgcacgcga cggcggtcca cgtcccgctc
    14281 ggcgtcctgc tgttcggctt cagcctcgtg cagctgagcc ggatccggcc cctgccacgg
    14341 gaagcagcgg tcacggcggc gccttgatga ccgcggtgaa agtctgccga tccatgtgtc
    14401 ccctcatccg agatacttga acgcgcaacc aaatgcgagt actagtggca ccaaggccga
    14461 gacggcccgt ccatacctca ggggagtatc gatgcgtctt gggttcagcc ttccggtgtt
    14521 cggcaaggcg gcggccacac caggtgggat cgcgcggtac gcgcgtacgg cggagcaggc
    14581 cggggcggcc agtctctggg tcggcgaccg gttgctgtcg ccggtaaacc cggaggtggc
    14641 ctacccgggc tacgacacca tgcccgagga gttttggacc gcccaggatc cgttcaccgc
    14701 actggccgtc gccgccgccg tgaccgaaac cgcgatcctc gggtccagca ccatcaacgc
    14761 gacgcagtac cagcctgcca acttcgccag gctgctgacc agcatcgacg tggccagcaa
    14821 cggccggctg ctccccggcc tgggcatcgg ctggtcaccc gacgaatacg cggccgtcgg
    14881 cgttccgatg gcggaacgcg gcaagcggct ggacgaccta ctcgatcttc tcgacacctg
    14941 gtggaccaag gacaccgtgt cacacaacgg catcggctac acgattccgg agacccacgt
    15001 ccacctgaaa ccggtacgca agccgcccgt acacctggcc gggttcggcg agagggcact
    15061 gcgccgggtc gccgagcggg cggacggctg gctgccggtc tggacggtgc ccgaaaccat
    15121 ccccgccgac atgctcacct ccaccctggc caagatccgg gccgacgccg aacaagccgg
    15181 tcgcgacccg cggacactgg gcgtggcgct gcgagtgaat gccgccccgg acacgaagcc
    15241 ggaactcatc gccgaatcgg tgacgaagat cgtcgcgaca cttgcgccgg accacacctt
    15301 cgtcgacctc acctacctga ccagcagcgt agaggaacac atcgacctca ccggccgcct
    15361 actggaactg accgcccgag gctgaaagcg gcacgccggt gaaaacggag acgaaacgga
    15421 gcccataggg ccatgaacag gtctcgcgaa acgcgaggca tcaccatgtc gatcttgagc
    15481 cgccaagggg gctcgaaccc ctgaccttct gtttacaaga cagatgctct accagctgag
    15541 ctatagcggc cttgcccagg acaacctggg caaggcaagt atatcggcgc ccgttcagcg
    15601 ctccgcaggg cgcacccgcg ggtccccggc cactgtccgg aaggcgtgcc cgaacgtcac
    15661 ggcggtcgcc gggtcgcggc ggtcgatgac gtagtaccag tggggtccgg ggtcacttcg
    15721 aggacgcccg cgccgtgcga gtcgagttcc acgaagcgca cgtgcgggtt cagcgcgcgg
    15781 atcgcggctt cgaccttcag cgagccggtc cgcggcggga cgcctcgtcg atgttgtccg
    15841 aggtgaccga cgggtacacg aactcgacgg cgacgctcgc tgcgtcccgc ggcacgtcgt
    15901 tcgcccaggg ggcgatggtg tcgaggaccc ggcggcgtcc cattggtcgg tgttgagcgt
    15961 ggccggccgt cgagcgcagg cagggcgggg atcttgatcg gcgtgaccat caccgagttc
    16021 ccgatcaggt tccaggacgc ggtcccgcgc gcgaggccgc ccagtcaccc tcggtcgccg
    16081 ggtggtgtga cggcgatccg ccggaccagg cgttgtcggc gacctcgtgg tcgtcccagg
    16141 tcgcgatcat cgggtggcgg gcgtgcagcc gccgcaggtg ctcgtcggtc ttgtacatcg
    16201 cgtgacgttg tcggtaatcc gccagggtga tcaactcatt gggcggtacc gaaggccgaa
    16261 gatcacccgc agggttggga ctcccttcgt agaggtagtc acccaggtga atgaaggcgt
    16321 ccagatcgtc gcggccggac agatagccgt agggggcgaa gtgaccgaca gcccagttcg
    16381 cacacgagac cacgccgaag cgcaggctct cgacgtcctc gtcgcgcgaa ggcgccgtgc
    16441 gggtccggcc ggtctgcgag accttcccct gagacgtgaa ccggtaccaa tacccggtcg
    16501 ccgcgcgcag cccgcccgcc gtcaccttca ccgtgtggtc gcgttccggc ccggtccgaa
    16561 ggtgaccgcg agcgacgacg cgcgcgaagc cggcatcggc ggccaccgcc gccccttttc
    16621 cggatcccgg aaccgcctca ggcgaagggg tgacgcgggt ccagagaagg accgaatcgg
    16681 gcatcgggtc tcccgaagcc accccatgcg cgaaaaccgg ggcctccgcc ccgttagata
    16741 cacccgaaag ggtgaacgtc gccgcggttc cggcggctgt cacgccgacc gcgcgaagaa
    16801 cggaacgcct gctcacagcg gacgtcatgg catgccgtgt gccgtaaacc ggcaaggtct
    16861 cgatgatctt cctccgacgt ggtggacgcc acttcaggtt tcctgcaacg gtcgaggcac
    16921 cgcccccgat gctcctcggg aaagtccctc gaaccagagt gaggaggtgg atcgatcatg
    16981 aagatcaacg agcacaccac gggagccaag cgcggcgaac gcggtgtcga aaagaaccag
    17041 gacgaaacac ccgaacgtgg cgaatggctg ctggaagcgc cgcgccagcg tgacggagag
    17101 cgatcgatcc cccagactcg ctcgcaccgg ccgaatctgc tgcgccgccg tgcctggcag
    17161 atcctcgaag cgccgacggc cgagcagccc gccgtcgacg tcgacgaggc gatgggcccg
    17221 cagccgccgg acgacacaac ggtcaacttc gtcctggatc tcgtcctgcg catcggcgag
    17281 gtccagatgt cgagcggcgc cggcgcctcc gacgtcaccg cgacgatcat cgcgcttacc
    17341 tccgcgctcg gcctcccgca ctgcgaggtc gacgtgatct tcacgtcgat cacggtgacc
    17401 tgccaccgcg gcaccgacat ggcaccggtg acggcgctgc gcgtggtccg ttcgcgcagc
    17461 ctcgactaca cgcggctcac ccagaccgag accctggtcc gccggatcgt gcgcggcaac
    17521 atcggcgccg aagaggccca gcaggaactg cagcggatca cgaccgcgcc gcacccgtac
    17581 ccccgttggg tggccacggc cgcttggggc gggctggccg cgttcatcac cctgatcctc
    17641 ggcggcagca tcgacgtcgc cctggtcgcg ctggtgatca gcgcggtcat cgaccggctc
    17701 ggccggttct tgaaccgctt cgcgctgccg ttcttcttcc agcaggtgat cggcggtctg
    17761 gtcgcgacgc tgtccgcgat ggcgatagtc agcagcaacc tgctcaccac ggacaaaccc
    17821 acgctggtcg tcgcggcggc cgtcaccgtg ctgctgtccg ggctctccac ggtttccgcc
    17881 gtgcaggatg ccatcaccgg ctactacgtc acggcggccg ggcgcacgac cgagaccgcg
    17941 ctgatgagcg ccgggctgat cgcgggcgtg gtgctcgccc tgaagatcgc ggtactgctc
    18001 ggcctgccgc tgaccccgct gcccgaggtc gtttcctcga ccccgcagca gttgccgatc
    18061 atcgtcatcg gcagcgtcgg cgcgtcggcc tgcttcgcgc tggcctcgta ttcgaccctg
    18121 cgcgcgatga tcgtcgcggg agcggccggg gcgatcggcg gcgccgtgta cggcgcgctg
    18181 atgctgaccg atttccaggc cgtcagctcc tccgcggtcg ccgcgacact ggtcggtttc
    18241 tgcggcggcg tgctcgccag gcgcctcaag gtgacgccgc tcgtggtggc tgtgtccggc
    18301 atcacgcccc ttctccccgg cctctccacc tatcgtggtc tataccaatt gggcgtcgaa
    18361 cccggcggga acatctcgac gctgatgacc gcggtcgcga tcgggcttgc cctggcagcg
    18421 ggtgtggtac tcggcgaata cctggcgcaa ccggtgcgca cggggctcgg caggctggaa
    18481 cgcaaattcg ccgggccgcg gatggcgggt ccgctggaac ccgccgaacg acgcttggag
    18541 tgatcgctcg gcgacgggcc gcggcctcct cgcgcgatag ggtttccgct tagggcagcg
    18601 acccgcgatt cgagggagcg gctggtggac gaagtgattg ccgagacgag cagaacggcc
    18661 tccgcggatt tcgtggtggt ggcgaaccgg ctcccggtgg acctcgaacg gaccgccgac
    18721 ggaagcaggc gctggacggc gagcccgggc gggctggtgt ccgcgctcga accgttcctg
    18781 cggtcacgca agggagcctg ggtcgggtgg cccggtgtgc ccgacgtcga cgtcgaggag
    18841 ttcgacgacg acggcttggt gctgcacccg gtctccctga cgtcggacga cgtccgcgac
    18901 tactacgaag gtttctccaa cgcgacgctc tggccgctgt accacgacgt ggtggcgcgg
    18961 ccggtgttcg accggagctg gtgggagtcc tacgtccggg tgaaccggcg cttcgccgag
    19021 gcgagcgcga aggtcgccgc cgagggcgcg accgtgtgga tccaggacta ccagctgcag
    19081 ctggtcccgg cgatgctccg cgagctgcgt ccggatctcc ggatcgggtt cttcctgcac
    19141 atcccgttcc ccccggtcga gttgttcatg cagatgccgt ggcggaccga gatcgtccgc
    19201 ggcctggtcg gggccgacct cgtcggtttc caccggccgg gtggcgcgca gaacttcctc
    19261 tggctggcgc ggcagctggc cggtctcgaa tccagccgcg gcgcggtcgg catccgcacc
    19321 cgccccggcc tgatgcaggt cggcgaccgc acggtgcggg tcggcgcgtt cccgatctcc
    19381 atcgacgcca tcggcctcga caaactcgcc aagaccaagg gcgtcgccga acgcgccgcc
    19441 cagctgcgcc gtgacctggg caatccgaag aaggtgctgc tcggcgtcga ccggctcgac
    19501 tacacgaagg gcatcgacct gcggttgcag gcgctgcacg agttgctgca cgagggccgc
    19561 gtccgtccgg aggacgtcac gttcgtccag ctggccacgc cgagccgcga gcgcgtcgag
    19621 cactaccagc ggatgcgcgg cgacatcgag cagatggtcg ggcggatcaa cggggagttc
    19681 gcgcgcgtcg gtcacccggt cgtgcattat ctgcatcagt ccgtgaaccg gacggaactg
    19741 gccgcgttct tctccgcggc cgacgtcatg gtggtcactc ccctgcgtga cgggatgaac
    19801 ctcgtctgca aggagtacgt cgcctgccgc cacgacctgg gcggttcgct cgtgctttcg
    19861 gagttcgccg gcgccgcggc ggagctgacc agcgcgctcc tggtcaaccc gcatgatctg
    19921 gacggggtga agaacgcctt ggagactgcc attacgctcg accccgcaga gggacgccgc
    19981 cgtatgcgcg ccatgcgtcg acaggtcctc acgcatgacg tcgaccgctg ggcgcgctcg
    20041 ttcctccaag cgctcggtgc cgaaccggcc gactaatccc cctaccccgc atagtttccc
    20101 gaggagaaat cgttgaccgc cgaggcactg cccgccgagc tgcggcgtgc gatcgttcag
    20161 gtcgcgcgca ccccgcggct gctggtcgcc tgcgactacg acggcacgct ggctccgatc
    20221 acggccaacc cggacgaagc ccgtcccctg cccgaatcgg tgggcgcgct caggtcgctg
    20281 gccggcctgc acgagacgac caccgcggtc atctcgggcc gcgcgctgcg tgatctcgcc
    20341 actctttccc gccttccggc cgaggtgaac ctggtcggca gccacggatc cgagttcgac
    20401 atcggcttca tccacgcgct cgacgacaag gcccgcgaac tccacagacg gctggaggcc
    20461 gagctggaga acctggtgct cgacgtgccg ggtgtctcgc tcgaggtcaa gcccgccagc
    20521 atcgcggtgc acgtccgccg cgccgagcac gaggcgggcc gccgggtcct tcgcgatgtc
    20581 cacaatggac cttcgaagtg ggagggcgtg tccacgaccg acggcaagga ggtcgtcgag
    20641 ctcgcggtcg tccagacgga caagggccgc gcgctggaca ccctgcgcca ccaggtcggc
    20701 gcgacggcgg cggtcttcct cggcgacgac gtcaccgacg agaaggcgtt cgcccggatc
    20761 tccggcccgg atctcggcgt gaaggtcggc gacggcgaaa gcctcgccca gtaccgggtt
    20821 ccggacaccg tcgacgtcgc gatggtgctc gccttcctgc tcgaagagcg gcgcaactgg
    20881 ctctacggcg agcaggctcc gccgatcgag cggctttcgc tgctggccaa cgaacgttcg
    20941 gtcgcgctgg tcacgccgga cgcccggctg acctggctgt gccaccccgg ccccgacgcg
    21001 cccgcgatct tcgcggatct gctcggcggt gccggcgcgg gccacttctc gatcaagccg
    21061 caccgcaacg gcctgccgct cgggcagcgt tacctgccga acacgatgac cgtcgagacc
    21121 cgctggtcgc ggctgctcgt caccgactac ctcgagccag agagccccgc gcaccgcacg
    21181 gatctcgtcc gggtgatctc gggcgagacg gcggcggaga tcgtgttcgc gccgcggccc
    21241 gaattcggcg gtgtgccggt gaagctggtc gccgagggcg acgggatcct ggtgcagggc
    21301 acctcggaac cgttcgcgct gcgctcgccg ggagtgacgt gggagatcac ctccgacggc
    21361 atgaacgaca ccgcgaccgc gctcgtcacc ccctcgccgg agaacccggt ggtgctcgaa
    21421 ctccgttgcg gcacttcgga tctcggtgag cacgaactgt ccgaagtgga gcgacgggcc
    21481 cgcgcgggcg actactggag cacctgggcg cggacgctca agctgcccag cgtccagacc
    21541 gatctcgtcg gccgctcggc gctcaccctg cgcggcctgg tgaacaccga caccggcggg
    21601 gtgctcgcgg cggcgacctc ctcgctgccg gaggagatcg gcggcgtccg caactgggac
    21661 taccgctact gctggatccg cgacgcggcc atgaccgtgc gcgaactggt ccacctcggc
    21721 tcgaccgaag aggccgaagg ctacctgcgg tggctgcacg gcgttctgtc cactttggcc
    21781 ggtccggaac ggctgcaccc gctgtacacc ttggcgggca gcgtgatcgg cgccgaagcg
    21841 gtcatcgaat cgctgcccgg atacgccggt tcgcggccgg tccgcgtcgg caacctggca
    21901 aaccaccagg tgcagctgga cgtgttcggc ccggtcgtcg aactcgtgca gacgctcgcg
    21961 gaggcgcgcg gtgaactgcg cgacgaggac tggcagatgg tgcgcgcgat ggccgaggcc
    22021 gtcacgcggc gctggaacga gccggaccac ggcatctggg aggagcggca cgtgccgcgc
    22081 caccgggtgt actcgcgggt gatgtgctgg gtgaccatcg accgggcgat caaactgggc
    22141 gaggtcta
//
