LOCUS       NC_021252              23493 bp    DNA     circular CON 28-MAR-2024
DEFINITION  Amycolatopsis keratiniphila, complete sequence.
ACCESSION   NC_021252
VERSION     NC_021252.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis keratiniphila
  ORGANISM  Amycolatopsis keratiniphila
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
REFERENCE   1  (bases 1 to 8948591)
  AUTHORS   Tang,B., Wang,Q., Yang,M., Xie,F., Zhu,Y., Zhuo,Y., Wang,S., Gao,H.,
            Ding,X., Zhang,L., Zhao,G. and Zheng,H.
  TITLE     ContigScape: a Cytoscape plugin facilitating microbial genome gap
            closing
  JOURNAL   BMC Genomics 14, 289 (2013)
   PUBMED   23627759
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8948591)
  AUTHORS   Xu,L., Zhao,W., Ge,M. and Zhao,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAR-2012) Shanghai Laiyi Center for Biopharmaceuticals
            R&D, Shanghai 201203, China
COMMENT     ##Taxonomic-Update-Statistics-START##
            This Genome (query)               :: GCA_000400635.2
            Current Name                      :: Amycolatopsis keratiniphila
            Previous Name :: Amycolatopsis orientalis HCCB10007
            Date Updated                      :: 2018-10-26
            Analysis Type :: Average Nucleotide Identity (ANI)
            Analysis 1 (A1) :: Query vs. TYPE genome for current name
            A1 Genome (subject)               :: GCA_001620365.2
            A1 Name                           :: Amycolatopsis keratiniphila
            A1 ANI                            :: 96.94781%
            A1 Query Coverage                 :: 84.86%
            A1 Subject Coverage               :: 83.93%
            Analysis 2 (A2) :: Query vs. TYPE genome for previous name
            A2 Genome (subject)               :: GCA_000478275.1
            A2 Name :: Amycolatopsis orientalis HCCB10007
            A2 ANI                            :: 90.22668%
            A2 Query Coverage                 :: 73.73%
            A2 Subject Coverage               :: 73.08%
            ##Taxonomic-Update-Statistics-END##
            ##Assembly-Data-START##
            Assembly Method                   :: Newbler v. v2.5
            Sequencing Technology :: Sanger dideoxy sequencing; 454; Illumina
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000400635.2-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 02:04:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,307
            CDSs (total)                      :: 8,242
            Genes (coding)                    :: 8,193
            CDSs (with protein)               :: 8,193
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 33 of 49
            Pseudo Genes (internal stop)      :: 3 of 49
            Pseudo Genes (multiple problems)  :: 1 of 49
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:56:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2462197
            Orig. end                         :: 2485690
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003410.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Shanghai Laiyi Center for
            Biopharmaceuticals R&D, Shanghai 201203, P.R. China,
            hccbred@gmail.com.
            The organism was changed from 'Amycolatopsis orientalis HCCB10007'
            to 'Amycolatopsis keratiniphila' in October 2018.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23493
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="7"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23493
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23493
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13493](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13493)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    79..92
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.93"
                     /tool="antismash"
     misc_feature    complement(272..287)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.97"
                     /tool="antismash"
     misc_feature    complement(776..790)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(1007..1021)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    1151..1164
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.74"
                     /tool="antismash"
     misc_feature    complement(1226..1240)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            1281..2117
                     /locus_tag="AORI_RS52490"
                     /old_locus_tag="AORI_2300"
     CDS             1281..2117
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029321.1"
                     /locus_tag="AORI_RS52490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2300"
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="WP_016332678.1"
                     /transl_table=11
                     /translation="MTQTGERRRPAEPGRRPRSERVKRTPRAERTQRLKERRGRRSVYD
                     RRRTARPNRHKELRRRWVALLSVLTAVALVYLLWFSSMLGVRQVDVVGASSVPADQIRA
                     AAAVPDQKPMLRLDTDEIRDKVAQMPGIATVDVSRSWPSTLEITVTERNAIAFFDSGPG
                     GDGVHLVDGGGVVFKTVKERPAGLPELKLPLVSADDPVTRAVTGVLGVIPQQLLKQVTT
                     ATAKTPGSVEFALADGKTVRWGTSADTERKAKVLAALLTREGKVFDVSAPDLPTVS"
     gene            complement(2202..2951)
                     /locus_tag="AORI_RS52495"
                     /old_locus_tag="AORI_2301"
     CDS             complement(2202..2951)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332679.1"
                     /locus_tag="AORI_RS52495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2301"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_016332679.1"
                     /transl_table=11
                     /translation="MDFERSLDLLWRDRGEARQPTRGRKPKLTLDQVIATAVTLADRAG
                     EATVSMSQIAKELGAGTMTLYTYVPGKTELLDLMVDSVLAERNLPGPGDPRPDGWREQV
                     RLYAERTLAVFRAHPWLRSTSMVRPVLGPGLMAGQEYVIAAVSDIGLEPRKAAAAANSI
                     EIYVQANATLFAETAQVEQETGQSTDAWWGQRSVFWEKYFDVTRHPAMTRIWESGGYDA
                     DTCEAADETFAFGLERMLDGIEALVTR"
     gene            3047..3880
                     /locus_tag="AORI_RS52500"
                     /old_locus_tag="AORI_2302"
     CDS             3047..3880
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637674.1"
                     /locus_tag="AORI_RS52500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2302"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_016332680.1"
                     /transl_table=11
                     /translation="MTILVTGATGSVGRLLVDELVEAGAPVRALTVNPAKAALPEQVEV
                     AKGYLGKPETLPEALEGIETVYLAPLAAKVDDFVKLAKEAGVRRVVALSGSNADDPAEN
                     SSGVDYAIIEKAVEAAGFDWTFLRPGAFMNNTLGWAETIKAERVVREAYPESRMTPIDL
                     ADIAAVAAHVILTEGHVGKKHTLSGPTAISQREQVAAISAALGEEVVFQELTREEANKQ
                     WAAAGIPAEIAEWLLDGFAYFTENPDKPTGVVQELTGRPGVTYAEWAVANVEAFR"
     gene            complement(3939..4703)
                     /locus_tag="AORI_RS52505"
                     /old_locus_tag="AORI_2303"
     CDS             complement(3939..4703)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029318.1"
                     /locus_tag="AORI_RS52505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2303"
                     /product="hypothetical protein"
                     /protein_id="WP_016332681.1"
                     /transl_table=11
                     /translation="MSFFTDGPRSRPLFPVPEQELFGYNGRPWVETPHEYIVPAILPWS
                     MPLGRAERTIVALRGIEVWPESVSFQLSVYSRDLLLDEPGEGLIDHRRVPDYNALLVGV
                     LFPDGRRASSETISVPSATKPDQPVLRAQGLGGSAFHVDHEIFLWPLPPDGPLEFIVQW
                     LDRDIEESRTSLDGTAIRDAAKEAGEIWPGLPARKSHGLPVRRVGAQAMITPAWPRESQ
                     APPPLPQPSSPPPASDQPRGAPLPTRLPRRAR"
     gene            complement(4827..6884)
                     /gene="pknB"
                     /locus_tag="AORI_RS52510"
                     /old_locus_tag="AORI_2304"
     CDS             complement(4827..6884)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029317.1"
                     /locus_tag="AORI_RS52510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2304"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_016332682.1"
                     /sec_met_domain="Pkinase (E-value: 6.1e-46, bitscore:
                     155.8, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTDPTLVGTLLEGRYRVDKLLARGGMSSVYRGVDTRLDRQVAI
                     KIMDPRFADDRSFVERFEREARSAARLHHPHVVAVHDQGFDTPGGEESGRAFLVMELVD
                     GGTLRELLDERGPLDVALALSITEPVLSALAAAHAAGLVHRDVKPENVLIGRGGTALSG
                     GVVKVGDFGLVRAVASAGTTSSSVILGTVAYVSPEQVATGATTSRGDVYSAGILLYEML
                     TGRPPYTGDTALSVAYRHVNDDVPRPSELRPGIPPQLDELILRATRRDPEQRPADAAAF
                     LAELNHLRTVLGVPAVPVPVPLPADADRETDAERTTPGIPAVPAVAPASAATTVLPPVA
                     EATLPVTGPRGTQALHREPQIPAAQPPRTPPPRPKPAAGDEQPGSRKRLYLMIAAAVLV
                     LGGLIGAFAFILNDSGPTSSSVPKLAGMNQAAAGDALRSAKLTPAYTEEYSDTAAQHTV
                     IRSDPAEGTALAPGATVNVVLSKGRPIVPDIQAGTSQQDAETAIKAAQLTPVQGEQEYS
                     DVAKNKVIRVDPGPGSQLNIGGQVTIILSKGPEPLPPVPDVTGQTKDAAFQILQQAGFQ
                     PFQAGEEFSDQFAAGQVIRTDPKGGGKASNRRIGVFVSNAVEVPNVTFKRMEEAIQILK
                     QAGLEPDRQGRGNGNGHGGGNGGFDFVLEQDPQPGTKVPKGTKVKIKGFG"
     misc_feature    complement(6903..6916)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.59"
                     /tool="antismash"
     gene            7070..7438
                     /locus_tag="AORI_RS52515"
                     /old_locus_tag="AORI_2305"
     CDS             7070..7438
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657740.1"
                     /locus_tag="AORI_RS52515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2305"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_016332683.1"
                     /transl_table=11
                     /translation="MSGIPVADDVLDADVAVLPLPEVATALNVSANKVRQMLRDGHLIA
                     VRRKGELYVPAAFLVKDGVVKGLAGTITVLADAGFSRTEMLRWLFAEDETLPGITPVNA
                     LRTSHGTEVKRRAQAMAF"
     gene            complement(7407..8573)
                     /locus_tag="AORI_RS52520"
                     /old_locus_tag="AORI_2306"
     CDS             complement(7407..8573)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029315.1"
                     /locus_tag="AORI_RS52520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2306"
                     /product="MFS transporter"
                     /protein_id="WP_016332684.1"
                     /transl_table=11
                     /translation="MRGRYSLAVYLAGATVARTGDELSGPALLLLGVSVGGSAATGSAL
                     LAGLTISAAAGGPLLGALLDRSPRPGRLLAWALLAYAGGLGAVLALVEVPAAIAVAVAA
                     GLLNPALAGGWTAQLPQVRGATPLERASTLDAMTFTAASLAGPGLAGLVAAYAGAPAAV
                     ALAITLVAAAFPAAWSLPATEAKPTRPIRRQLADGFAVLFRNRALLRATATSTVSFVGI
                     GIAVVCYPLLGAQRLGNPGFGALLLTVMAAASLVANAVLARRPPPPDRTVLVSTVLLGA
                     SFLLAATGPGVVPLLAAAVLAGFAEGPQLSALFAIRHREAPAAVRAQVFTTAASVKITG
                     LAVGAAAAGPLSALSVTAALGAAAGFQLLAAATYALMGARRPSPARAA"
     misc_feature    8574..8588
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.79"
                     /tool="antismash"
     gene            8596..9156
                     /locus_tag="AORI_RS52525"
                     /old_locus_tag="AORI_2307"
     CDS             8596..9156
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156491.1"
                     /locus_tag="AORI_RS52525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2307"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_016332685.1"
                     /transl_table=11
                     /translation="MTSAQRDFLPGRSARAAAQRAVDLLVVLLSPDPSVSSVRSVLEAH
                     GETSVELAPSDVVSLREAALQLREVFAARDVAEAADVLNRLLARYAHPPRLTDHADGFG
                     WHLHVDAADDGPWGAWLVTSSALALAVLLSDRQAPPGGLCAASGCGKPFAYLGGGSPRR
                     YCSTRCATRERVAAHRRDRSRMS"
     misc_feature    8773..8775
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9216..10004)
                     /locus_tag="AORI_RS52530"
                     /old_locus_tag="AORI_2308"
     CDS             complement(9216..10004)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637668.1"
                     /locus_tag="AORI_RS52530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2308"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_016332686.1"
                     /transl_table=11
                     /translation="MTSASNRKIRIGVQLQPQHAEYKAIRRAASEAEELGVDIVFNWDH
                     FYPLYGEPEGLHYECWTMLGAWAESTSRVEIGALVTCNSYRNPELLADMARTVDHISDG
                     RLILGIGSGWFEKDYDEYGYEFGTAGGRLDDLAEALPRIESRFGKLNPAPTRKIPVLIG
                     GGGEKKTLRLVAKHADIWHGFGDPEVVERKVKILDQHCADVGRDPKEIERSVAVEGEPE
                     ELGPKLLELGVSLFTVATGGPDYNLDKLRSWIEWRDKQQS"
     gene            complement(10001..10930)
                     /locus_tag="AORI_RS52535"
                     /old_locus_tag="AORI_2309"
     CDS             complement(10001..10930)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029312.1"
                     /locus_tag="AORI_RS52535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2309"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_016332687.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-111,
                     bitscore: 371.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 8.6e-61,
                     bitscore: 204.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSELDAAGITEPALRAAYTECRRINAHYGRTFFLATRLLPPRTRP
                     FAHALYGFARMADEVVDNPAPGTDPAIALDEVAAMVAQVFEGGTPADPVLTALADTVRR
                     HDLDRELFDAFLRSMAMDLKITEYATYADLKEYVHGSAEVIGLQMLPIFGTVVPAEEAV
                     PGAAALGEAFQLTNFLRDVGEDLDRGRLYLPADELAAFGVDRELLEFSRARGLPDRRVR
                     RALAVAVARNRAVYRRAEAGIPLLRAESRECVRTALVLYEGILDEIVALGYDVLNTRAV
                     VPRRRRLGVALPGLLASTWSNSRLRLRS"
     gene            complement(10927..12402)
                     /gene="crtI"
                     /locus_tag="AORI_RS52540"
                     /old_locus_tag="AORI_2310"
     CDS             complement(10927..12402)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637666.1"
                     /locus_tag="AORI_RS52540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2310"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_016332688.1"
                     /sec_met_domain="DAO (E-value: 5.8e-19, bitscore: 67.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVTGPSDHVVVIGGGLAGLSAALHLLGAGRRVTLLEQDKTPGG
                     RAGQADFGGNTVDTGASVLTMPELLDEAFSAVGESLADNLTLTRLDPAYRARFADGSTI
                     AVHTEAAAMEAEIREAAGPAEAEGYRRLRRWLTELYAVQKDHFIGANFDSPFDLVRPEL
                     AKLAALGGFGRLGPKIGGFLRDDRVRRLFSFQALYAGLDPARAIGAYGVISYMDTVGGV
                     YYPSGGMGEIARAMAKAAERAGAELRFGTEAAWLERVSSRVRAVRTRTGERIPCDTVVL
                     ATELGTAYRLLGARPRRPLPLRYSPSAVVLHGHAPKSWPDLGHHTIFFGHAWEKTFSEI
                     IREGKLMSDPSLLVTRPTATEPALAPGGDQVISVLAPAPNLGRGKIDWDRVGPAYRAEL
                     LRTLENRGLTGFADDFSVDEMITPAGWAERGLTAGTPFSLAHTFAQTGPFRPGNLMRAV
                     DNVVLAGCGTTPGVGIPPVVISGRLAAGRVTGR"
     gene            complement(12402..13493)
                     /locus_tag="AORI_RS52545"
                     /old_locus_tag="AORI_2311"
     CDS             complement(12402..13493)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332689.1"
                     /locus_tag="AORI_RS52545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2311"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_016332689.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-46, bitscore:
                     157.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTSAYDADLPAHVERALAGFLERAGAEIRRTEPTVGAGIDALAG
                     FVLGGGKRLRPTFAWWGWRGAGGDPGGPDVEGVLQAVASLELIQACALIHDDLIDSSDS
                     RRGSPTVHIAGAKLHADSGWLGSPSTFGLATAVLVGDLALAWADDMFGEAPLPPAALAA
                     ARPAWRAMRTEVLAGQYLDVRTQATGDASPEAALHICKLKTAAYTVQRPLHLGAALGGA
                     DDALIATLREFGDEVGVAFQLRDDLLGVFGDPSVTGKPAGDDLREGKRTLLVALGLQRA
                     AEQGKDAAAKVISDAIGDAHLSEDAVETVREALQDVGAVDAVERRIDELTDSAMAALDR
                     AHLAEPAPAALTGLVVKATQRTY"
     gene            complement(13562..14110)
                     /locus_tag="AORI_RS52550"
                     /old_locus_tag="AORI_2312"
     CDS             complement(13562..14110)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637664.1"
                     /locus_tag="AORI_RS52550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2312"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_016332690.1"
                     /transl_table=11
                     /translation="MDTHWDGYDSIGGSVPLDLVNTVSWRRDPARREDRLSAPERLSEW
                     VVLVGAGTERLEIPEAVLEAVKDFRETLYRVLVSDPPDVTALRKPLLAAYRHAGLTPSL
                     PLRWTVPLVDGTALPHFLALAAEELLRSGELDRIRECEGPGCGWIFTDHTRNRSRRWCS
                     SSDCGNRARVKRHYDKTRG"
     gene            14158..14826
                     /locus_tag="AORI_RS52555"
                     /old_locus_tag="AORI_2313"
     CDS             14158..14826
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029308.1"
                     /locus_tag="AORI_RS52555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2313"
                     /product="AzlC family ABC transporter permease"
                     /protein_id="WP_016332691.1"
                     /transl_table=11
                     /translation="MTTLRHNYLAGARVGLGLGVATFVLGVTFGAYSQTLGWGIAAPIV
                     ASIVVFSGSAQFAMATALAGGGNLAVAVGAAALINARFLPMGAAVAADLRGGRLRRAWE
                     GQAVVDGSWVAAHLGEGRFDREKLIGCTLVQLPAWVLGTVLGVLAAPPPDVVSRFGLDV
                     VFPGFFLVLLIDELRRSRQAVLTAVLAACLAGILVLFVPVGLALIGASAAALVGLGVRR
                     "
     gene            14823..15128
                     /locus_tag="AORI_RS52560"
                     /old_locus_tag="AORI_2314"
     CDS             14823..15128
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637662.1"
                     /locus_tag="AORI_RS52560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2314"
                     /product="AzlD domain-containing protein"
                     /protein_id="WP_016332692.1"
                     /transl_table=11
                     /translation="MTLWLAIVLVALVSIGFKAAGPVLLGDRTLPPRVAAVIALLAPAL
                     LAGLVLTDVTGPAWSGVDWTLCAGLAAIAVTYMLRVPVLAAILCGVVVTAVLRFLV"
     gene            complement(15125..15802)
                     /gene="merB"
                     /locus_tag="AORI_RS52565"
                     /old_locus_tag="AORI_2315"
     CDS             complement(15125..15802)
                     /EC_number="4.99.1.2"
                     /GO_function="GO:0018836 - alkylmercury lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0046413 - organomercury catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="merB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156527.1"
                     /locus_tag="AORI_RS52565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2315"
                     /product="organomercurial lyase"
                     /protein_id="WP_016332693.1"
                     /transl_table=11
                     /translation="MSAETDTSWDEDVRVAVYRAFAEHGRPPTAPELADAAHGSLAVAK
                     QALHRLAERRHLVLDECEHVVLAHPFAAIPLGFSVMGERTLWWGGCAWDAFAIPHLVKA
                     EPEVLVSTRCRGCGEPQALMVNDRTPPKGDLVAHFLVPVARMWDDVVHTCANQRLFCDE
                     SCVDEWLTETGQDKGYVMDLATLWRLAAGWYDGRLDHGYTRRDPAAAAAYFAQAGLSGP
                     FWH"
     gene            15939..16823
                     /locus_tag="AORI_RS52570"
                     /old_locus_tag="AORI_2316"
     CDS             15939..16823
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332694.1"
                     /locus_tag="AORI_RS52570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2316"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_016332694.1"
                     /transl_table=11
                     /translation="MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAY
                     MSITYGAGGSSRDGTIRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNI
                     LALRGDPPGDVYGDWVPHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADT
                     EYLVRKLRAGADFAIAQLFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIK
                     LSGAPAPRRLLDRLEPLAGDPKAFRAEGIDAVTELCERLIAEGVPDLHFYTFNRSKATR
                     EVVGRLGLVPARA"
     gene            16866..18551
                     /locus_tag="AORI_RS52575"
                     /old_locus_tag="AORI_2317"
     CDS             16866..18551
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075033.1"
                     /locus_tag="AORI_RS52575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2317"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_043847995.1"
                     /transl_table=11
                     /translation="MASTARSVHEICDRYVDEYAAADPVAATTFGISGYDDQLTDYSPA
                     GHAARAAIARRALAEIAAAEPVGDGERAAKAVFSERIALNLEIHEAGLDLAALNVIESP
                     VQELRMVFDFMPTETAEDWATIAARMARVPEALDGLRTSLLAAADAGRVSALRQVGKVA
                     EQAETWAGLKDETGFFETLVADAKDVDEKLRAELGQAAHAAQEAYAEFAGFLRAELAPL
                     APVKDAVGAEVYQLWSRVFTGATLDLDEAYAWGWAEFTRLETEMREVAGRIKPGATLAE
                     AAAALDADPKYLVRGRAEFQAWMQNLSDNALKSLRGKHFDISDRVMALECKIAPPGGTV
                     GAYYTGPSEDFSRPGRMWWSLPQGRDEFTTWREVSTVYHEGAPGHHLQIATAVDQSESL
                     NKYQRLLAFTSGHAEGWALYSERLMEDLGFLADDGELFGMLSEQLFRAARVIVDIGMHL
                     ELEIPSGTGFHEGERWTPELGLEFMLTRTVTDPAHVHDEIDRYLGWPGQAPSYKLGERL
                     WLTAREEARARQGDAFDIKQFHTRALALGGMGLDTLREMLAALD"
     gene            18847..19728
                     /locus_tag="AORI_RS52580"
                     /old_locus_tag="AORI_2318"
     CDS             18847..19728
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637657.1"
                     /locus_tag="AORI_RS52580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2318"
                     /product="DMT family transporter"
                     /protein_id="WP_016332696.1"
                     /transl_table=11
                     /translation="MSVAVPTRARSSAALVLAGVLWGTGGLAGSLLASRAGLHPLSVAA
                     YRLLIGGVIATGYLWLTGGLRGLPRTPQARRRLLAVGGLFALFQTSYFASVSLSSVSVA
                     TMTTIGSAPVLLAVATVVKTHRLPGAWTAVSLAGSLAGLALLQWTPGQEVNVAGVLFAL
                     LAAAGFAALTLVTATRVEGLDPLPTTAFGCLIGGAALTPAALWFGMAVPLQADVLALVV
                     YFGVVPTALAYAAYFRGLESAHPVLAALSALLEPLTAALLSMAVLGERLGAVGWCGAVV
                     LIAALAVAYTKP"
     gene            complement(19725..20288)
                     /locus_tag="AORI_RS52585"
                     /old_locus_tag="AORI_2319"
     CDS             complement(19725..20288)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332697.1"
                     /locus_tag="AORI_RS52585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2319"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_016332697.1"
                     /transl_table=11
                     /translation="MTAMSSECTRYVQLSADEFRARLPEALTIYVNAMRYPEGTAEQRA
                     PMWLTHALREGWRCMAALDADGVLLGLAYGYKGRGGQWWHEQVRHGLTRREGQAAAEHW
                     MSDYFELTEIHVSPESQGKRIGEDLLRRLLDGVPSAHVLLSTPEGTSRAWNLYRRVGFV
                     DVLRDYHFAGDPRPFAILGRTLPL"
     gene            complement(20285..20806)
                     /locus_tag="AORI_RS52590"
                     /old_locus_tag="AORI_2320"
     CDS             complement(20285..20806)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156538.1"
                     /locus_tag="AORI_RS52590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2320"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_016332698.1"
                     /transl_table=11
                     /translation="MSTIDHPSVAKVAAALAEAGQQAAADGIRILPAEVRTAAQAAEAL
                     GVEVGAIANSLVFRSGTGDAETALLALTSGAHRADTGLLASLTGADEIGKADADFVRAH
                     TGQPIGGVAPVGHPKALTTLVDTALRAHEVVWAAAGHPKSVYPTTFDGLVALTGGTPAD
                     VAGDGQDGRP"
     misc_feature    complement(20420..20422)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    20872..20888
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.35"
                     /tool="antismash"
     misc_feature    complement(20912..20927)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: strong, score: 28.4"
                     /tool="antismash"
     misc_feature    20913..20926
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 22.19"
                     /tool="antismash"
     misc_feature    complement(20913..20926)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.17"
                     /tool="antismash"
     gene            21028..21510
                     /locus_tag="AORI_RS52595"
                     /old_locus_tag="AORI_2321"
     CDS             21028..21510
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156540.1"
                     /locus_tag="AORI_RS52595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2321"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_016332699.1"
                     /transl_table=11
                     /translation="MSVSVVSPDEAERPGGTAQPALPMSLRPPAPPAAVSLYAQARRGL
                     AEAERESDPAERFIGAYLAALRGAAAVLEARGRPHRGRARPASGWVLLDSVAPELKEWA
                     AFFAANSATRAAAQAGITGKVTVELADELTRAATVFLELVRRVVHGLPMGDSAYVA"
     gene            21535..22299
                     /locus_tag="AORI_RS52600"
                     /old_locus_tag="AORI_2322"
     CDS             21535..22299
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637653.1"
                     /locus_tag="AORI_RS52600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2322"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_016332700.1"
                     /transl_table=11
                     /translation="MAGQAMIDQGRFLEVIGAETELMAQVAHTASADAPVPTCPGWTLG
                     EVLRHVGSVYRVTRRWITDGRRPEHWQRKPGPGQSLEEFFREGRDELVAELSAHDPDEL
                     APTWWPADRSYGFWRRRMAHETTIHRIDAESAAGREVSEIPEDVAVDGIDEALVLWFGQ
                     RLPLLGLSGTKTGSVGVRTAGHTWIARAGPTETVAWRCSAEEAQRADDLITGKPDKIYR
                     WLWGRAGPTAVTVSGDQDMAGQLWALLRLATR"
     gene            22361..23044
                     /locus_tag="AORI_RS52605"
                     /old_locus_tag="AORI_2323"
     CDS             22361..23044
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156546.1"
                     /locus_tag="AORI_RS52605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_2323"
                     /product="VOC family protein"
                     /protein_id="WP_016332701.1"
                     /transl_table=11
                     /translation="MVAHLVNLVFDSALPRDLAGFWEGLFSWDAPFEPAFRSETRPKGR
                     KNRLHLDLASRSPGHQAELVDRALSLGARHIDVGQGPPEEKRVPWVVLADPEGNEFCVL
                     EPREQYEGTGAIAAVVVDALDPERLARFWAAALGWEIGVREETIVGLRPPDGRGPWVEF
                     LATKADKVERNRLRFEIAPGPGGSRAAEVRRLLGLGAIGRGTARRGAVSLVDPEGNEFS
                     VLTPR"
     misc_feature    23399..23417
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.79"
                     /tool="antismash"
ORIGIN
        1 cagggcgccg agatcgccgt cggccagcgc gccgagaacc tcgacgcctt ccccgagggg
       61 ccgtcctcgg tgatcgtgtc gaccgcgatc aaggacgaca acccggaact gatggccgcg
      121 cgggaacgcg ggatcaccgt gctgcaccgc gcgcaggcgc tggccgggct gatggagggg
      181 catcgcgtcg cctgcatcgc cgggacgcac ggcaagacgt cgacgacgtc gatgctgacg
      241 gtcgcgctgc agcagtgccg tctcgacccg tcgttcgcca tcggcggcga cctcaacgag
      301 tcgggcgcga acgcgcacca cggcgagggc ggcgtcttcg tcgccgaggc cgacgagagc
      361 gacggatcgt tcctggcgta ctcgccgtcg gtggccgtgg tgaccaacgt cgagccggac
      421 cacctggacc accacggcac ggccgaggcg tacgtctcgg tgttcagcga cttcctcggc
      481 cggatcgtgc cgggcgggct gctcatcgtc tgcggtgacg acgagggcgc ctcggagctg
      541 ggagcgaggg cgtcggagca gggcatccgc gtccgtcgct acgggcgttc ggtcaccggc
      601 gccgacgacg cgaaggtgct cgactacgca cccgcgccgg acggcggcgt cgtccggatc
      661 tccttgcagg gcgaggagat cgtcctccgg gtcgcggtgc cgggtgagca catggcgctg
      721 aacgcgatcg ccgcgctgct ggccgggatc gagctcggcg cgccggtcga aggactggcc
      781 gaggggctcg ccgcgttcgg cggcgtccgg cggcggttcg agttcaaggg ccgcgcgggc
      841 gacgtccgcg tgtacgacga ctacgcgcac cacccgaccg aggtcgacgc gcagctgcgc
      901 gcggtgcgga cggccgcggg ctcgggccgg gtcgtcgtgg tcttccagcc gcatctgtac
      961 tcgcgcacga agacgttctc gaaggagttc gcggccgcgc tgtcgctggc cgacgaggtc
     1021 gtcgtgctgg acgtcttcgg ggcgcgcgag aagccggagc ccggggtgag cggcgcgctc
     1081 atcgccgatc agatctccgg tgtcccggtg cactaccagc ccgcgttcga cgtcgcggcg
     1141 aagctcgcgg cggatctggt ccaacccggc gacctgctgg tgaccatggg cgccggcgac
     1201 gtcacgcagc tcggcccgga gatcctggcc gaactggacc ggcgggcggg ctagcccatg
     1261 acaacgcccg gcggccagcc atgacacaga ccggggaacg ccgccgcccg gccgaacccg
     1321 gtcggcgtcc gcgctccgaa cgggtcaagc ggaccccacg ggctgaacgg actcaacggc
     1381 tgaaggaacg gcgcggcagg cggtcggtgt acgaccgccg ccgcaccgcc cggccgaacc
     1441 ggcacaagga gctgcggcga cgctgggtcg cgctgctctc ggtgctgacc gccgtcgcgc
     1501 tcgtctacct gctgtggttc agctcgatgc tgggggtgcg gcaggtcgac gtcgtcgggg
     1561 cgagctccgt gcccgcggac cagatccgcg ccgcggcggc cgtgccggac cagaagccga
     1621 tgctgcgcct ggacaccgac gagatccggg acaaggtggc gcagatgccc ggcatcgcca
     1681 ccgtcgacgt ctcgcggtcg tggccgagca ccctcgagat caccgtgacc gaacggaacg
     1741 cgatcgcgtt cttcgacagc gggcccggcg gcgacggcgt gcacctcgtc gacggcgggg
     1801 gagtggtgtt caagaccgtc aaggaacggc ccgccgggct gcccgagctc aagcttccgc
     1861 tggtgtcggc cgacgacccg gtgacccgcg cggtgaccgg cgtcctcggc gtgatcccgc
     1921 agcagttgct caagcaggtc accaccgcga cggcgaagac ccccggcagc gtcgagttcg
     1981 cgctggccga cgggaagacc gtgcggtggg ggacctcggc cgacaccgaa cgcaaggcga
     2041 aggtcctggc cgcgctgctc acccgcgagg gcaaggtctt cgacgtctcg gcccccgatc
     2101 tgcccaccgt ctcctgactc cctgtcgcgc gagtgtcatg aaagggtcgt tcaggacatc
     2161 ttttgtcctg aacgaccctt tcatgacact tcagggcgtg ctcagcgggt gacgagggct
     2221 tcgatgccgt ccagcatgcg ttccaggccg aacgcgaagg tctcgtcggc ggcttcgcag
     2281 gtgtccgcgt cgtagccgcc gctctcccag atccgcgtca tcgccggatg gcgcgtcacg
     2341 tcgaagtact tctcccagaa caccgaccgc tgcccccacc aggcgtccgt cgactgcccg
     2401 gtctcctgct cgacctgcgc cgtctcggcg aagagcgtcg cgttggcctg cacgtagatc
     2461 tcgatgctgt tcgcggccgc ggccgccttg cggggctcca gcccgatatc cgacaccgcc
     2521 gcgatcacgt actcctggcc cgccatcagc ccggggccga gcaccgggcg caccatcgac
     2581 gtcgaacgca gccacggatg cgcccggaac acggccaagg tgcgctcggc gtagagccgc
     2641 acctgctcgc gccagccgtc cggccgcgga tcgccggggc cgggaaggtt ccgttcggcg
     2701 agcacggagt cgaccatgag atcgagcagt tccgtcttgc cggggacgta ggtgtagagc
     2761 gtcatcgtgc cggcgccgag ttccttggcg atctggctca tcgacacggt cgcctcgccc
     2821 gcgcggtcgg cgagcgtgac ggcggtggcg atcacctggt cgagggtcag tttgggcttc
     2881 cgtcccctgg tcggctgccg ggcttcgccg cggtcacgcc acaacagatc gaggctgcgc
     2941 tcgaagtcca tccacactcc actcggccgt gaagctggat tctacattct cgtatgaggt
     3001 acggttaaat tcatcccgta gggcgtacga aaaggagtgg ggaatcgtga cgatcctggt
     3061 gaccggtgcg accggaagcg tcggcaggct gctcgtcgac gaactggtgg aggccggggc
     3121 gccggtacgg gcgctgaccg tcaacccggc gaaggcggcg ctgcccgagc aggtggaggt
     3181 cgccaagggc tacctgggca aaccggagac gctgccggaa gccctcgaag gcatcgagac
     3241 cgtgtacctg gcaccgctcg cggccaaggt ggacgacttc gtgaagctgg cgaaggaggc
     3301 cggagtgcgc cgtgtggtgg cgctgtcggg cagcaacgcc gacgacccgg cggagaattc
     3361 gagcggtgtg gactacgcga tcatcgagaa ggccgtcgag gcggcgggtt tcgactggac
     3421 gttcctgcgg ccgggcgcgt tcatgaacaa cacgctcggc tgggcggaga cgatcaaggc
     3481 cgagcgggtg gtccgcgagg cctaccccga gtcgcggatg acgccgatcg acctcgcgga
     3541 catcgccgcc gtcgcggcgc acgtcatcct caccgagggg cacgtcggca agaagcacac
     3601 gctgagcggg ccgacggcga tcagtcagcg cgaacaggtc gccgccatct cggccgcgct
     3661 cggcgaagag gtggtcttcc aggagctcac cagggaagag gcgaacaagc agtgggccgc
     3721 cgccgggatc ccggccgaga tcgccgagtg gctgctcgac ggcttcgcgt acttcaccga
     3781 gaaccccgac aagccgaccg gcgtcgtcca ggaactcacc gggcggcccg gcgtcaccta
     3841 cgcggagtgg gcggtggcga acgtcgaagc cttccgctga tctttggcct cgtgagtggt
     3901 aaggacggtt ctaaccgtcc ttaccactca cgaggccctc agcgggctcg gcgcgggagg
     3961 cgggtcggca gcggagcgcc ccgcggctgg tccgaagcgg gcggcgggga cgatggctgg
     4021 ggcagcgggg gcggggcctg cgattcgcgc ggccaggccg gggtgatcat cgcctgcgcc
     4081 ccgacccggc ggacgggcag cccgtgcgac ttccgcgcgg gcagtcccgg ccagatctcg
     4141 cccgcctcct tggcggcgtc gcggatggcg gtgccgtcga gcgaggtgcg cgactcctcg
     4201 atgtcgcggt cgagccactg gacgatgaac tccagcgggc cgtcgggcgg cagcggccac
     4261 aggaagatct cgtggtcgac gtggaacgcc gaaccgccca gcccctgcgc gcgcagtacc
     4321 ggctgatccg gtttggtagc cgacggcacg gagatggtct ccgaactggc ccgcctcccg
     4381 tcggggaaga gcaccccgac cagcaacgcg ttgtagtccg ggacccggcg gtggtcgatc
     4441 aggccttcgc cgggttcgtc gagcaggaga tcccgcgagt acaccgacag ctggaaggac
     4501 accgactccg gccacacctc gatgccgcgc agcgccacga tggtccgttc ggcccggccc
     4561 agcggcatcg accagggcag gatcgccggg acgatgtact cgtgcggcgt ctccacccag
     4621 ggacggccgt tgtagccgaa cagctcctgt tccggcaccg ggaacagggg gcggctgcgc
     4681 ggaccgtccg tgaagaagct catcgcggcg cggcggaacg cggggtgaag ctgtccgacc
     4741 tgccgttcac gccgtcgacg accaccatgc gctcacggta gccgatgacc atgccggtac
     4801 tgaacggttt caaagcacct ttcgcgtcac ccgaagccct tgatcttcac tttcgtgccc
     4861 ttgggcacct tggtgcccgg ctgcggatcc tgctccagga cgaagtcgaa accaccgttt
     4921 ccgccgccgt gaccgttccc gtttccgcga ccttgacggt ccggctccag acccgcctgt
     4981 ttcaggatct ggatcgcctc ctccatccgc ttgaaggtca cgttcggtac ttcgacggcg
     5041 ttcgaaacga acacaccgat ccggcggttg ctcgccttgc cgccgccctt cgggtcggtg
     5101 cggatcacct gaccggcggc gaactggtcg gagaactcct cgcccgcctg gaacggctgg
     5161 aagcccgcct gctgcaggat ctggaacgcc gcgtccttgg tctggcccgt gacgtccggg
     5221 accggcggca gcggctcggg gcccttggac aggatgatcg tgacctgccc gccgatgttc
     5281 agctgcgaac cggggcccgg gtcgacgcgg atcaccttgt tcttggcgac gtcgctgtac
     5341 tcctgctcgc cctggaccgg ggtcagctgc gcggccttga tcgccgtctc cgcgtcctgc
     5401 tggctcgtcc cggcctggat gtcgggcacg atcggacggc ccttcgacag cacgacgttg
     5461 accgtggcgc ccggcgcgag cgccgtgccc tccgccgggt cggaccggat caccgtgtgc
     5521 tgcgcggcgg tgtcgctgta ctcctcggtg taggccgggg tcagcttcgc cgaccggagc
     5581 gcgtcgccgg cggcggcctg gttcatcccg gccagcttcg gcaccgacga cgacgtcggg
     5641 cccgaatcgt tgaggatgaa ggcgaacgcg ccgatcaggc cgccgaggac caggaccgcg
     5701 gccgcgatca tcaggtagag ccgcttccgc gaccccggct gctcgtcgcc ggccgccggt
     5761 ttggggcgcg ggggaggcgt gcggggcggc tgcgcggccg ggatctgcgg ctcgcggtgc
     5821 agcgcctgcg ttccgcgcgg cccggtgacc ggaagggtcg cctcggcgac cgggggcagc
     5881 acggtcgtcg cggcggaggc cggagccacc gcggggacgg cggggatgcc gggggtggtg
     5941 cgctcggcgt cggtctcccg gtcggcgtcg gcgggcagcg ggacgggcac cgggaccgcc
     6001 gggacaccga gaacggtgcg cagatggttc agctcggcga ggaacgccgc ggcgtcggcg
     6061 gggcgctgct cggggtcgcg gcgggtggca cgcaggatca gctcgtccag ctgcggcggg
     6121 atacccggcc gcagctcgct cgggcgcggg acgtcgtcgt tgacgtgccg gtacgccacc
     6181 gagagcgcgg tgtcgccggt gtacggcggg cgtccggtga gcatttcgta cagcaggatc
     6241 ccggccgaat agacgtcgcc gcgcgaagtg gtcgcgccgg tcgcgacctg ctcgggcgag
     6301 acgtaggcga cggtgccgag gatgacgctc gaactcgtgg tgcccgcgct cgcgacggcg
     6361 cggaccagcc cgaagtcgcc gaccttgacc acaccgcccg aaagcgcggt cccgccgcgg
     6421 ccgatgagga cgttctccgg tttgacgtcg cggtgcacca gaccggcggc gtgcgccgcg
     6481 gccagcgcgg agaggaccgg ttcggtgatg ctcagcgcga gcgcgacgtc caggggaccg
     6541 cgttcgtcga gcagctcgcg cagggtcccg ccgtcgacga gttccatcac caggaacgcg
     6601 cggccggact cctcgccgcc tggggtgtcg aagccctggt cgtgcaccgc caccacgtgc
     6661 gggtggtgca gccgggccgc cgaacgggct tcccgttcga agcgttcgac gaaggacctg
     6721 tcgtcggcga accgcgggtc catgatcttg atggcgacct ggcggtcgag gcgggtgtcg
     6781 acgccgcggt acaccgacga catcccaccg cgtgcgagca gcttgtccac ccggtagcgg
     6841 ccctcgagca gagtgcccac cagcgtgggg tccgtgcgtg tcacggctat ggatcgtacg
     6901 gaagtaccca tgttctggtg tacgggacct gggtcgccgg ggatcacgat tcccgtcatt
     6961 tcgtcgaatc ggcggtatcc gtgaccgggt ggatactctc cgtcatggcc cggctcgtca
     7021 cccgtgcgca ctaacggagg gggagacgga atgtggcaca gtgtcacctg tgagtggtat
     7081 tcccgtcgcc gacgacgttc tcgatgccga tgtggccgtc ctcccgcttc cggaggtcgc
     7141 gaccgcgctg aacgtttcgg ccaacaaggt ccgccagatg ctgcgcgacg gccacctgat
     7201 cgccgtccgg cgcaagggcg agctgtacgt cccggccgcg ttcctggtga aggacggcgt
     7261 ggtcaaaggc ctggcgggca ccatcaccgt gctcgcggac gccgggttca gccggacgga
     7321 gatgctgcgc tggctcttcg ccgaagacga gaccctgccc gggatcacgc cggtcaacgc
     7381 gctccgcacc agccacggca ccgaggtcaa gcggcgcgcg caggcgatgg ccttctagct
     7441 cccatcagcg catacgtggc ggccgcgaga agctggaatc ccgccgcggc acccagcgcg
     7501 gcggttacgg agagtgcgct cagtggcccc gcggccgcgg ctccgaccgc gagcccggtg
     7561 atcttcacgc tcgccgccgt cgtgaagacc tgagcccgca ccgccgcggg tgcttcgcga
     7621 tgccggatgg cgaacagtgc cgaaagctgc gggccttccg cgaaaccggc gagtacggcg
     7681 gcggccagca ggggcaccac gccgggcccg gtggccgcga gcaggaaact cgcgcccagc
     7741 aggacggtgc tgacgagcac ggtgcgatcc ggcgggggcg gtctgcgggc cagcacggcg
     7801 ttcgcgacca gtgacgcggc ggccatcacg gtgagcagga gcgcgccgaa ccccggattc
     7861 cccagccgct gggcgccgag cagcggatag cagaccacgg cgatcccgat gccgacgaag
     7921 gacacggtgg acgtcgcggt ggcccgcagc agcgcgcggt tgcggaagag gaccgcgaac
     7981 ccgtcggcga gctgacggcg gatcggtctc gtgggcttcg cttcggtggc gggcagcgac
     8041 catgcggcgg ggaaggcggc cgcgaccagc gtgatcgcga gcgcgaccgc ggccggtgcg
     8101 ccggcgtacg cggccacgag cccggcgagt cccggcccgg cgaggctcgc ggcggtgaac
     8161 gtcatcgcgt ccagcgtgct cgcccgctcc agcggtgtcg cgccgcgcac ctgcggcagc
     8221 tgcgccgtcc acccgcccgc caacgcgggg ttgagcaacc cggccgcgac ggccacggcg
     8281 atcgccgcgg ggacttcgac cagcgcgagc accgcgccga gcccgcccgc gtacgcgagc
     8341 agcgcccacg ccagcagccg tcccggccgg ggactgcggt cgagcagggc gccgagcagc
     8401 ggcccgcccg ccgccgcgga gatcgtcagg cccgcgagca gtgcggatcc ggtggcggcc
     8461 gagccgccga cactcacgcc gagcaggagc aaagccggcc cggacaactc gtcgccggtc
     8521 ctggcgaccg tcgcgccggc caggtagaca gcgagactgt aacggcctct catggacgag
     8581 acgttacagt ggggtatgac ttcagcgcag cgggatttcc tgcccggccg gtcggcgcgg
     8641 gcggcggcac agcgggcggt ggatctcctg gtcgtcctac tgtcgccgga tccgtcggtt
     8701 tcctcggtcc gttccgtgct ggaagcgcac ggggagacct cggtcgagct ggcgccgtcg
     8761 gatgtggtgt cgttacgcga ggcggccttg cagctgcggg aggtgttcgc ggcgcgggat
     8821 gtcgcggagg cggccgatgt gctcaaccgg ctgctggccc gctacgcgca tccgccgcgg
     8881 ctgaccgatc acgcggacgg gttcggctgg catctccacg tggacgccgc cgacgacggg
     8941 ccgtggggcg cgtggctggt gacgtcgtcc gcgctggcgc tggccgtgct gctgtcggac
     9001 cgtcaggcgc cgccgggcgg gttgtgtgcc gcttcggggt gtgggaagcc cttcgcgtac
     9061 ttgggtgggg ggagtccgcg tcggtactgc tcgacgcggt gcgccactcg ggagcgggtg
     9121 gcggctcacc gtcgcgatcg gtcccggatg tcatgaaagg gtcgttcagg acaaaagatg
     9181 tcctgaacga ccctttcatg acatttgcga gcgggtcagg actgctgctt gtcccgccac
     9241 tcgatccagg accgcagctt gtccaggttg tagtcgggcc cgccggtcgc cacggtgaac
     9301 agcgagacac ccagctccag cagcttcggc cccagctcct cgggctcgcc ctcgacggcg
     9361 accgaacgct cgatctcctt cgggtcgcgc cccacgtcgg cgcagtgctg gtcgaggatc
     9421 ttgaccttgc gctccaccac ctccgggtcg ccgaagccgt gccagatgtc ggcgtgcttc
     9481 gcgaccaggc gcagcgtctt cttctcgccg ccgccaccga tcagcaccgg gatcttgcgg
     9541 gtcggcgccg ggttcagctt gccgaaccgg ctctcgatac gcgggagcgc ctcggccagg
     9601 tcgtcgagcc ggccgcccgc ggtgccgaac tcgtagccgt attcgtcgta gtccttctcg
     9661 aaccagccgg agccgatgcc gaggatcagc cgtccgtcgg agatgtggtc gacggtgcgg
     9721 gccatgtcgg cgagcagttc gggattgcgg tagctgttgc acgtcaccag cgcgccgatc
     9781 tcgacccgcg acgtcgattc cgcccaagcg cccagcatcg tccagcactc gtagtgcagt
     9841 ccttcgggct cgccgtagag cgggtagaag tggtcccagt tgaagacgat gtccacaccg
     9901 agctcttcgg cctccgaagc cgcccggcgg atcgccttgt attcggcgtg ctggggctga
     9961 agctggacgc cgatccggat cttcctgttc gaagcagagg tcatgaccgc agcctaagcc
    10021 tggagttgct ccacgtgctc gccaatagcc ccggcagagc gacacccagc cgacggcggc
    10081 gcgggacgac cgcgcgggtg ttcaacacgt cgtatccaag ggccacgatc tcgtcgagga
    10141 tgccttcgta gagcacgagc gcggtccgca cgcattcgcg ggattccgcg cgcagcaacg
    10201 ggatgcccgc ttcggcgcgg cggtacacgg cgcggttgcg cgccaccgcg acggcgagcg
    10261 cgcgccggac gcgacgatcg ggcaggccgc gggcgcggga gaattcgagc agctcacggt
    10321 cgacgccgaa cgcggccaat tcgtcggccg gcaggtacag ccgccctcgg tcgaggtcct
    10381 cgccgacgtc gcgcaggaag ttggtcagct ggaacgcctc gcccagcgcg gcggcaccgg
    10441 gcaccgcctc ctcggccggg acgacggtgc cgaagatcgg caacatctgc agaccgatca
    10501 cctcggccga accgtggacg tactccttga ggtcggcgta ggtcgcgtac tcggtgatct
    10561 tgaggtccat cgccatggag cgcaggaacg cgtcgaacag ttcgcggtcg aggtcgtggc
    10621 gccgaacggt gtcggcgagc gcggtcagca ccgggtcggc gggcgtgccg ccctcgaaga
    10681 cctgcgcgac catggcggcg acctcgtcca gcgcgatcgc gggatcggtg ccgggggcgg
    10741 gattgtcgac cacttcgtcc gccatccggg cgaagccgta cagcgcgtgc gcgaacggcc
    10801 gcgtgcgtgg cggcagcagc cgggtcgcga ggaagaaggt gcggccgtag tgcgcgttga
    10861 tgcggcggca ttcggtatac gcggcccgca acgccggctc ggtgatcccc gcggcgtcga
    10921 gttcgctcat cggccggtga cccttcccgc cgcgagcctg ccggagatca ccaccggcgg
    10981 gatgccgaca cccggcgtgg tcccgcagcc ggccaggacg acgttgtcca ccgcccgcat
    11041 caggttcccc ggccggaacg ggccggtctg ggcgaaggtg tgcgcgagcg agaacggcgt
    11101 gcccgcggtg agcccgcgtt ccgcccagcc cgcgggggtg atcatctcgt cgacggagaa
    11161 gtcgtccgcg aagccggtga ggccgcggtt ttccagcgtg cgcaggagtt ccgcgcgata
    11221 cgcggggccc acgcggtccc agtcgatctt gccgcggccg aggttcggcg cgggggccag
    11281 taccgagatc acctggtcgc cgccgggggc gagggccggt tcggtcgccg tcggccgggt
    11341 caccagcagc gagggatcgc tcatcagctt gccttcgcgg atgatctccg agaacgtctt
    11401 ctcccaggcg tggccgaaga agatggtgtg gtggcccaga tccggccacg acttcggcgc
    11461 gtgcccgtgc aggacgacgg ccgacggcga gtaccgcagc ggcagcggac gccgggggcg
    11521 ggcgccgagc agccggtacg cggtgccgag ttcggtcgcg agaaccaccg tgtcgcaagg
    11581 gatccgctca cccgtgcggg tccgcaccgc acgcacccga gaggaaaccc tttccagcca
    11641 agcggcttcg gtaccgaagc gcagctccgc gccggcgcgt tcggccgcct tcgccatcgc
    11701 ccgcgcgatc tcgcccatgc cacccgacgg gtagtagacc ccgccgacgg tgtccatgta
    11761 ggagatgacg ccgtacgcgc cgatcgcgcg cgccggatcg agccccgcgt agagcgcctg
    11821 gaaggagaac agccggcgca cccggtcgtc gcgcaagaac ccgccgatct tcgggccgag
    11881 ccgtccgaaa ccgcccagcg cggccagttt cgccagctcc gggcgcacga gatcgaacgg
    11941 cgagtcgaag ttcgcgccga tgaagtggtc cttctgcacc gcgtacagct cggtcagcca
    12001 gcggcgcagc cgccggtagc cctcggcctc ggccggaccg gcggcctcgc ggatctcggc
    12061 ctccatcgcc gccgcctcgg tgtgcacggc gatcgtgctg ccgtcggcga acctcgcgcg
    12121 ataggccggg tcgagccgcg tcagcgtcag gttgtccgcc agggattcgc cgacggcgga
    12181 gaaggcctcg tcgagcagct cgggcatggt cagcacgctg gcgccggtgt cgacggtgtt
    12241 gccgccgaaa tcggcctgtc cggctcggcc gccgggcgtc ttgtcctgct ccagcagggt
    12301 cacccggcgt ccggcgccga gcaggtgcag cgccgccgac agcccggcga gcccgccacc
    12361 gatcaccacc acgtggtcac tcggaccggt gacagtgcgc atcagtaagt ccgctgggtc
    12421 gccttgacga ccagcccggt cagcgcggcg ggagcgggtt cggccaggtg ggcgcggtcg
    12481 agcgcggcca tcgcggagtc ggtgagctcg tcgatacggc gttccaccgc gtcgacggcg
    12541 ccgacgtcct gcagcgcctc gcgcacggtc tcgacggcgt cttcggacag gtgcgcgtcg
    12601 ccgatggcgt cggagatgac cttcgccgcc gcgtccttgc cctgttcggc cgcgcgctgg
    12661 agacccagcg cgaccagcag ggtccgcttg ccctcgcgca ggtcgtcgcc cgcgggcttg
    12721 ccggtgaccg acgggtcgcc gaacacgccg agcaggtcgt cgcgcagctg gaacgccacg
    12781 ccgacctcgt cgccgaactc gcgcagcgtc gcgatcagcg cgtcgtccgc accgccgagg
    12841 gcggcaccga ggtgcagcgg gcgctggacg gtgtacgcgg ccgtcttgag cttgcagatg
    12901 tgcagcgccg cctcggggga ggcgtcgccg gtggcctggg tgcggacgtc gaggtactgc
    12961 ccggcgagca cctcggtgcg catcgcccgc cacgccggcc gcgccgccgc gagggccgcg
    13021 ggcgggagcg gggcctcgcc gaacatgtcg tcggcccagg ccagcgcgag gtcgccgacc
    13081 aggacggcgg tcgcgagccc gaacgtgctc ggggaaccca gccagccgct gtcggcgtgc
    13141 agtttcgcgc ccgcgatgtg caccgtcggc gaaccgcggc gcgaatcgga ggagtcgatg
    13201 aggtcgtcgt ggatcagcgc gcacgcctgg atcagctcca ggctcgccac cgcctgcagc
    13261 acgccttcga cgtccggccc gcccgggtcg ccgcccgcgc cgcgccagcc ccaccaggcg
    13321 aacgtcgggc gcaggcgttt gccgccgccc agcacgaatc cggccagcgc gtcgatcccg
    13381 gccccgaccg tcggctcggt gcggcggatt tcggcaccgg cgcgctcgag gaacccggcc
    13441 agcgcccgct cgacgtgggc gggcagatcg gcgtcgtagg cggacgtgtc catgagcaca
    13501 tcctccggga aggacgtcgt cgtgacccag tcgggtgcct tcgaatgtgg cgaattagac
    13561 gtcagccgcg ggtcttgtcg tagtgccgct tcacccgcgc ccggttcccg cagtccgacg
    13621 aactgcacca gcgccgcgac cggttgcgcg tgtggtcggt gaagatccag ccacagccgg
    13681 gcccctcgca ctcccggatc cggtccagct ccccggaccg gagcagctct tcggccgcca
    13741 gcgccaggaa atgcggcaac gcggtgccgt ccaccagcgg caccgtccac cgcagcggca
    13801 gggagggcgt gagtccggcg tgccggtacg ccgccagcag cggcttgcgc agcgccgtga
    13861 cgtccggcgg atccgacacc agcacgcggt acagcgtctc gcggaagtcc ttcaccgcct
    13921 ccaggacggc ctcggggatc tccagccgct cggtgcccgc gcccaccagg acgacccact
    13981 cggacagccg ttccggagcg gaaagccggt cttcccgccg ggccggatcg cgccgccagg
    14041 aaacggtgtt gaccaggtcc aacggcacgc tcccgccgat gctgtcgtac ccgtcccagt
    14101 gggtgtccat gacttctcct aatggtcaaa actagtttag cttgttaggg tcgaaccatg
    14161 acaacgctcc ggcacaacta tctggccggc gcccgtgtcg ggctcggact gggtgtggcg
    14221 accttcgtcc tcggagtcac cttcggcgcg tacagccaga ccctcggctg ggggatcgcc
    14281 gccccgatcg tcgcttcgat cgtggtgttc tccggctcgg cccagttcgc gatggccacc
    14341 gcgctcgcgg gcggcggcaa cctcgccgtc gcggtcggcg cggcggccct gatcaacgcc
    14401 cggttcctgc cgatgggtgc cgccgtcgcc gccgatctgc gcggcggacg cctgcgccgc
    14461 gcgtgggaag gccaagccgt cgtcgacggt tcgtgggtcg ccgcccacct cggcgaaggg
    14521 cgcttcgacc gcgagaaact catcggctgc acgctcgtcc agttgcccgc gtgggtgctg
    14581 gggacggtgc tcggggtcct ggccgcgccg ccaccggacg tcgtctcacg gttcgggctc
    14641 gacgtggtgt tccccggctt cttcctggtc ctgctcatcg acgaactgcg ccgttcgcgc
    14701 caggcggtgc tgaccgcggt gctcgccgcc tgcctcgccg ggatcctggt gctgttcgtc
    14761 ccggtcgggc tcgcgctgat cggcgcttcg gccgccgcac tggtcgggct gggggtgcgg
    14821 cgatgacgct ctggctcgcg atcgtcctgg tggcgctggt cagcatcggg ttcaaggcgg
    14881 cgggaccggt cctgctgggc gatcggacgc tgccgccgcg ggtcgcggcc gtgatcgcgc
    14941 tgctggcgcc cgcgctgctg gccgggctcg tgctcacgga cgtcaccggc cccgcctggt
    15001 ccggggtcga ctggacgctc tgcgccggcc tggccgcgat cgcggtgacc tacatgctgc
    15061 gcgtgccggt gctcgccgcg atcctctgcg gggtcgtcgt cacggccgtg ctgcggttcc
    15121 tcgtctagtg ccagaacggg ccgctcagcc cggcctgtgc gaagtacgcg gccgcggcgg
    15181 ccgggtcccg gcgggtgtag ccgtggtcga gcctgccgtc gtaccagccc gccgcgagcc
    15241 gccacagcgt cgccagatcc atgacgtaac ccttgtcctg tcccgtttcc gtcagccatt
    15301 cgtccacaca ggactcatcg cagaagaggc gctggttggc gcaggtgtgc acgacgtcgt
    15361 cccacatccg cgccaccggg accaggaagt gcgcgaccag gtcacccttc ggcggggtcc
    15421 ggtcgttcac catcagcgcc tggggttcgc cgcagccgcg gcagcgggtg gacaccagca
    15481 cctcgggttc ggccttgacc agatgcggga tcgcgaacgc gtcccacgcg cagccgcccc
    15541 accacaacgt gcgctcgccc atcaccgaga acccgagcgg gatcgccgcg aacggatgcg
    15601 ccagcacgac gtgctcgcat tcgtcgagta cgagatgccg ccgctccgcg agccggtgca
    15661 gtgcctgttt cgccaccgcg agcgagccgt gggcggcgtc ggccagttcc ggcgccgtcg
    15721 gcggcctccc gtgctcggcg aacgcgcggt agaccgccac gcggacgtcc tcatcccagc
    15781 tggtgtcggt ctcggcgctc atggcggctc cctgtgctca ccaccgagtc tccccagccg
    15841 ggcaccgctc ggcaaccgct cgtacgtggc tcagatcgca cgcccatagc ctgagagggg
    15901 gctcccagcc agcggacatt cccccctaac atggccgtat gacgtcggtg gtcgagcgat
    15961 tgcagggtga tggacccgtg ttctccatcg agttcttccc gccccgggac gcggccgacg
    16021 aggccgtgct gtggaagtcg atccgggaac tcgagccgct ggatccggcg tacatgtcga
    16081 tcacctacgg cgcgggcggc tccagccggg acggcacgat ccgcagcatc gcccgcgtcg
    16141 ccaccgaaac cacgctggtg ccgatggcgc acctcaccgc cgtcaatcac tcggtcgcgg
    16201 aactgcgcaa tgtcatcggc tggtacgccg ccgtcggcgt gcggaacatc ctcgcgttgc
    16261 gtggcgaccc tccgggcgac gtctacggcg actgggtccc gcatccggac gggctgaact
    16321 acgccgaaga actcgtcgaa ctggtgcgtt cgctcggcga cttctgcgtc ggcgtctcgg
    16381 cgttccccta tggccacccg cgatcggcga acctcgaagc cgacaccgag tacctggtgc
    16441 gcaagctccg cgcgggcgcg gatttcgcga tcgcgcagct gttcttcgag ccggaggact
    16501 tcctccgcct gcgtgaccgg gtggcggcca ccggctgcga ggccctggtc atccccggca
    16561 tcatgccgct gaccacgccg cggacgctgc acacatccat caagctgtcc ggcgcgcccg
    16621 ccccgcggcg gctgctggac cggctcgaac cgctggcggg cgacccgaag gccttccgcg
    16681 ccgaagggat cgacgcggtg accgagctgt gcgagcggct catcgccgaa ggcgtccccg
    16741 acctgcactt ctacacgttc aaccggtcca aggccacgcg tgaggtggtc ggcaggctcg
    16801 ggctggtccc cgcccgggcg taactccgta ccgaagtcgc cttcgatccc ggtagcgtgc
    16861 cggtcatggc ttcaaccgcg cgaagtgtgc acgagatctg tgaccggtac gtcgacgagt
    16921 acgccgcggc cgacccggtc gccgcgacga ctttcggtat ctccggatac gacgaccagc
    16981 tgaccgacta ctcgcccgcc gggcacgcgg ccagggccgc gatcgccagg cgcgcgctgg
    17041 ccgagatcgc cgcggccgaa ccggtcggcg acggcgagcg cgcggccaaa gcggtgttca
    17101 gcgagcggat cgcgctgaac ctcgagatcc acgaagccgg cctcgacctc gcggcgctga
    17161 acgtgatcga aagccccgtg caggagctgc gcatggtctt cgacttcatg cccaccgaga
    17221 ccgcggagga ctgggcgacg atcgccgctc ggatggcgag ggtgcccgaa gcgctcgatg
    17281 gtctccgtac gtcgctgctc gcggccgccg acgcgggccg ggtgtcggcg ttgcggcagg
    17341 tcggcaaggt cgccgaacag gccgaaacct gggccgggct gaaggacgag accggtttct
    17401 tcgagaccct cgtcgccgac gcgaaggacg tcgacgagaa gctccgcgcc gaactcggcc
    17461 aggccgctca cgccgcccag gaggcgtacg cggagttcgc cgggttcctc cgcgccgaac
    17521 tcgccccgct ggcgccggtc aaggacgccg tcggcgccga ggtctaccag ctgtggtccc
    17581 gggtgttcac cggcgccacc ctcgacctgg acgaggccta cgcctggggc tgggccgagt
    17641 tcacccgcct cgaaacggag atgcgcgagg tcgccggccg gatcaagccc ggcgccaccc
    17701 tcgccgaggc ggccgccgcc ctcgacgccg atcccaagta cctcgtccgc ggccgggcgg
    17761 agttccaggc ctggatgcag aacctgtccg acaacgcgct gaagtcgttg cgcggcaagc
    17821 acttcgacat ctccgaccgg gtgatggcgc tggagtgcaa gatcgccccg cccggcggca
    17881 ccgtcggcgc gtactacacc ggcccgagcg aggacttctc ccgtcccggc cgcatgtggt
    17941 ggtcgctgcc gcagggccgg gacgagttca ccacctggcg cgaggtcagc accgtctacc
    18001 acgagggcgc gccgggacac catctccaga tcgcgaccgc ggtcgaccag tcggagtcgc
    18061 tgaacaagta ccagcggctg ctggcgttca cctccgggca cgccgagggc tgggcgctgt
    18121 actccgagcg gctcatggag gacctcgggt tcctcgccga cgacggcgaa ctgttcggca
    18181 tgctgtccga gcagctgttc cgcgccgcgc gggtgatcgt cgacatcggc atgcacctgg
    18241 aactggagat tccgtcgggc accggtttcc acgagggcga gcgatggacg cccgagctgg
    18301 gcctggagtt catgctcacc cggaccgtca ccgacccggc ccacgtgcac gacgagatcg
    18361 accgctacct gggctggccg gggcaggcgc cgtcgtacaa gctcggcgaa cggctctggc
    18421 tcaccgcccg cgaagaggct cgcgcgaggc agggcgacgc gttcgacatc aagcagttcc
    18481 acacgcgggc gctggcgctc ggcgggatgg ggctggacac gctgcgggag atgctggccg
    18541 ccctggactg agccgccgct cttccccgaa tgtcatgaaa gggtcgttcc tgacgaaaaa
    18601 tgtcaggaac gaccctttca tgacatctca ccctcggcgt gccgtaattc acgtgccccc
    18661 gctaccgcga ccttgatacg ttccctcccg tgcaccggat ctttctcgtc accccaccac
    18721 ccgcctcctg agcggggtgt gtccggccgc gcggcgctcc agccgcccgg ccgatccgtg
    18781 ctgcactgaa gcaccccgcg tcgtcgatgt cctttccgac agacacagac gcaggagcgt
    18841 ttccccatgt ccgttgccgt acccacgcgc gcccgatcgt cggccgcgct cgtcctcgcc
    18901 ggggtcctct gggggaccgg cggcctcgcc ggatccctgc tcgcctcccg cgcggggctc
    18961 catccgctga gtgtcgccgc gtaccggctg ctcatcggcg gcgtgatcgc caccggctat
    19021 ctctggctca ccggaggcct tcgcggcctt ccccgcacgc cacaggcccg tcgccgcctc
    19081 ctggcggtcg gcgggttgtt cgccctcttc cagaccagct acttcgcctc ggtctcgctg
    19141 agttccgtga gcgtcgcgac gatgaccacc atcggcagcg cgccggtgct gctcgccgtc
    19201 gcgacggtcg tcaaaaccca ccgcctgccc ggagcgtgga cggcggtgtc cctggccggg
    19261 tcgctcgccg ggctcgcgct gctgcaatgg acgccggggc aagaggtcaa cgtcgccggc
    19321 gtgctgttcg ccctgctcgc cgcggccggg ttcgccgcgc tgacgctcgt gaccgcgacc
    19381 cgcgtcgagg ggctggatcc cttgcccacc acggctttcg gctgcctgat cggcggtgcc
    19441 gcgctcactc ccgccgcctt gtggttcggg atggccgtgc cgcttcaggc cgacgtgctc
    19501 gcgctcgtcg tctacttcgg cgtcgtgccc acggcgctgg cgtacgccgc gtacttccgc
    19561 ggtctcgaaa gcgcgcatcc ggtgctggcc gcgttgtccg ccctgctcga accgctgacc
    19621 gccgcgctgc tgtccatggc cgtgctcggg gaacggctcg gcgccgtggg ctggtgcggc
    19681 gcggtggtgc tcatcgccgc gctcgcggtc gcctacacca aaccctagag cggcagcgtc
    19741 cggccgagga tcgcgaaggg ccgcggatcc ccggcgaagt ggtagtcccg cagcacatcg
    19801 acgaatccga cgcgccggta caggttccag gcccggctgg tgccttccgg cgtggaaagg
    19861 aggacatgcg cgctgggcac gccgtcgagc agccgtcgca ggaggtcctc gccgatccgc
    19921 ttcccctggc tttcggggct gacgtggatc tcggtgagct cgaagtagtc ggacatccag
    19981 tgctcggcgg cggcctggcc ttcacgccgg gtcaggccgt ggcggacctg ttcgtgccac
    20041 cactggccgc cgcggccctt gtagccgtag gcgagcccga gcaggacacc gtccgcgtcg
    20101 agcgcggcca tgcagcgcca gccttcgcgc agcgcgtgcg tgagccacat cggcgcgcgt
    20161 tgctcggccg tgccttcggg gtagcgcatg gcgttgacgt agatggtcag cgcctcgggg
    20221 agccgggcgc ggaactcgtc cgcggacagc tggacgtaac gggtgcattc cgaggacatc
    20281 gcggtcacgg gcgcccatcc tgcccgtcgc ccgcgacgtc cgcgggagtg cccccggtca
    20341 gcgcgacgag gccgtcgaac gtcgtggggt acaccgactt cggatgcccg gcggccgccc
    20401 agacgacttc gtgggcgcgt aacgcggtgt cgacgagggt ggtcaacgcc ttcgggtgac
    20461 cgaccggggc gacgccgccg atcggctgcc cggtgtgcgc gcggacgaaa tccgcgtccg
    20521 ccttgccgat ctcgtcggcg ccggtcagcg aagcgaggag gcccgtgtcg gcgcggtgcg
    20581 cgccggaggt cagggcgagc agggccgttt cggcgtcgcc cgtgccgctt cggaagacga
    20641 ggctgttcgc gatcgcgccg acctcgacac cgagcgcttc ggcggcctgg gcggccgtgc
    20701 ggacttcggc ggggaggatc cggatcccgt ccgcggcggc ctgctggccc gcctcggcga
    20761 gcgcggccgc gaccttggcc accgagggat ggtcgatggt gctcatacgc ctatgagatc
    20821 acgtggccga tgccgtgtcc cgcaccacat gcggcgatca ccccgctaca gggttgaaga
    20881 agtgggcact tcggggttac attggacttg ttcgaacaga cgttcgacat tcggtgagcg
    20941 cgcaccggta ggtgcccggc gcgggggcgg gggaagcgcc tcggcgccgg gcaccggccg
    21001 gcgctcacgt acaggaggag ggtcgtcatg tccgtttcgg tcgtgtcccc cgacgaagcc
    21061 gagaggccgg ggggcaccgc gcagcccgcc ctgcccatgt cgttgcgccc gccggcacca
    21121 cccgcggcgg tctccttgta cgcacaggcg aggcgggggc tcgccgaagc agagcgggaa
    21181 agcgatcccg cggagcggtt catcggtgcc tatctcgccg cgctgcgggg cgccgcggcg
    21241 gtactggagg cccgcggccg cccgcaccgg ggccgtgccc ggccggcgag cggctgggtg
    21301 ctgctcgact ccgtcgcgcc cgagctgaag gagtgggcgg cgttcttcgc ggccaactcg
    21361 gcgacgcggg ccgccgcgca ggcggggatc accggcaagg tcaccgtcga actggcggac
    21421 gagctgacgc gggccgccac ggtgttcctg gaactggtgc gacgggtggt gcacgggctg
    21481 ccgatgggtg actcggcgta tgtggcctga gcgaccgggg agagggggtg cccgatggcc
    21541 gggcaggcca tgatcgacca gggcaggttc ctggaggtga tcggcgccga aaccgagctg
    21601 atggctcagg tggcgcacac cgcgtccgcc gacgcgccgg tcccgacctg ccccggctgg
    21661 acactcggcg aggtcctccg gcacgtgggc agcgtgtacc gggtcacccg ccgctggatc
    21721 accgacgggc ggcgtcccga gcactggcag cgcaaaccgg ggccggggca gagcctggag
    21781 gagttcttcc gcgagggccg ggacgagctc gtcgccgagc tgtccgcaca cgatccggac
    21841 gaactggcgc cgacctggtg gccggcggac cgcagttacg ggttctggcg gcgccggatg
    21901 gcgcacgaga cgacgatcca ccggatcgac gcggaaagcg cggccggccg tgaggtctcg
    21961 gagatccccg aagacgtggc ggtcgacggg atcgacgagg cactggtgct gtggttcggc
    22021 cagcggctgc cgttgctcgg gctgtccggc accaagaccg gatcggtcgg tgtgcgcacc
    22081 gcgggccaca cctggatcgc cagagccggg cccacggaga cggtcgcctg gcggtgctcg
    22141 gccgaggaag cccagcgcgc ggacgatctg atcaccggga agccggacaa gatctaccgc
    22201 tggctgtggg gccgggcggg tccgacggcg gtgacggtca gcggagacca ggacatggcg
    22261 ggacaactct gggcccttct gcggctcgcg acccgatgac cggtcggtgg ggaagccaaa
    22321 ccggtcagaa gtgtcggtgg tgccgtctag gttcaccggt gtggtggcac atctggtgaa
    22381 cctggtcttc gattcggccc ttcccagaga tctggcgggt ttctgggaag ggctgttcag
    22441 ctgggacgcg ccgttcgagc cggcgttccg gtccgaaacg cggcccaaag ggcgcaagaa
    22501 ccggctgcat ctggatctgg cgagccgttc gcccgggcat caggccgagc tggtggaccg
    22561 tgcgctgtcc ctcggcgccc ggcacatcga cgtcggccag gggccgccgg aggagaagcg
    22621 ggtgccgtgg gtggtgctcg cggaccccga gggcaacgag ttctgcgtcc tcgagcctcg
    22681 agagcagtac gagggcaccg gcgccatcgc ggcggtcgtc gtcgacgccc tcgacccgga
    22741 gcggctcgcg cggttctggg cggccgcgct gggctgggag atcggcgtcc gggaagagac
    22801 gatcgtgggc ctgcggccgc cggacggtcg cggcccctgg gtcgagtttc tcgccacgaa
    22861 agcggacaag gtggagcgga atcggctgcg cttcgagatc gcgccggggc cgggcggaag
    22921 ccgggcggcc gaagtccggc gcctgctggg gctgggcgct atcgggcgcg gtacggcgag
    22981 acgaggcgcc gtgtccctgg tggatccgga gggcaacgag ttcagcgtgc tcacgccccg
    23041 ctgagtgttt cgccccggtt gcgcggcggc gtcgaacgct gacctgagcg aaacacccgc
    23101 gccgtgggca ggcaacaacc ggccgggacc gttgaggtca tggagaccta tcgagtccgg
    23161 cccaccctgg tccatcccgg cgaagagacg gcggccgcgt cggcctggcg tgtccggatc
    23221 cgcgtggacg accggcccgg cacgctggcc aggatcgcga tccggctggc cgacctcgag
    23281 tgcaacatcc tcgggctgtc ggtgctgccg gtgcccggcg gcgtgctcga cgagatcgtc
    23341 ctgcgtccgg ccaccggcct gcctcggcag ctgctcatcg acgcgatccg cgacgaagga
    23401 tgcgaatgct ccgcggtcgt cgacgcggat ctggcggaac tggtcgatcc ggccaccgcg
    23461 acgctcaccg cggccaaacg agccgtcgag gaa
//
