LOCUS       NC_021252              49699 bp    DNA     circular CON 28-MAR-2024
DEFINITION  Amycolatopsis keratiniphila, complete sequence.
ACCESSION   NC_021252
VERSION     NC_021252.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis keratiniphila
  ORGANISM  Amycolatopsis keratiniphila
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
REFERENCE   1  (bases 1 to 8948591)
  AUTHORS   Tang,B., Wang,Q., Yang,M., Xie,F., Zhu,Y., Zhuo,Y., Wang,S., Gao,H.,
            Ding,X., Zhang,L., Zhao,G. and Zheng,H.
  TITLE     ContigScape: a Cytoscape plugin facilitating microbial genome gap
            closing
  JOURNAL   BMC Genomics 14, 289 (2013)
   PUBMED   23627759
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8948591)
  AUTHORS   Xu,L., Zhao,W., Ge,M. and Zhao,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAR-2012) Shanghai Laiyi Center for Biopharmaceuticals
            R&D, Shanghai 201203, China
COMMENT     ##Taxonomic-Update-Statistics-START##
            This Genome (query)               :: GCA_000400635.2
            Current Name                      :: Amycolatopsis keratiniphila
            Previous Name :: Amycolatopsis orientalis HCCB10007
            Date Updated                      :: 2018-10-26
            Analysis Type :: Average Nucleotide Identity (ANI)
            Analysis 1 (A1) :: Query vs. TYPE genome for current name
            A1 Genome (subject)               :: GCA_001620365.2
            A1 Name                           :: Amycolatopsis keratiniphila
            A1 ANI                            :: 96.94781%
            A1 Query Coverage                 :: 84.86%
            A1 Subject Coverage               :: 83.93%
            Analysis 2 (A2) :: Query vs. TYPE genome for previous name
            A2 Genome (subject)               :: GCA_000478275.1
            A2 Name :: Amycolatopsis orientalis HCCB10007
            A2 ANI                            :: 90.22668%
            A2 Query Coverage                 :: 73.73%
            A2 Subject Coverage               :: 73.08%
            ##Taxonomic-Update-Statistics-END##
            ##Assembly-Data-START##
            Assembly Method                   :: Newbler v. v2.5
            Sequencing Technology :: Sanger dideoxy sequencing; 454; Illumina
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000400635.2-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 02:04:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,307
            CDSs (total)                      :: 8,242
            Genes (coding)                    :: 8,193
            CDSs (with protein)               :: 8,193
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 33 of 49
            Pseudo Genes (internal stop)      :: 3 of 49
            Pseudo Genes (multiple problems)  :: 1 of 49
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:56:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1952860
            Orig. end                         :: 2002559
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003410.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Shanghai Laiyi Center for
            Biopharmaceuticals R&D, Shanghai 201203, P.R. China,
            hccbred@gmail.com.
            The organism was changed from 'Amycolatopsis orientalis HCCB10007'
            to 'Amycolatopsis keratiniphila' in October 2018.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..49699
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /product="T1PKS"
                     /region_number="6"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..49699
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="neighbouring"
                     /product="azole-containing-RiPP"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22271
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22271
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12271](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12271
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(394..1164)
                     /gene="cobF"
                     /locus_tag="AORI_RS50105"
                     /old_locus_tag="AORI_1819"
     CDS             complement(394..1164)
                     /EC_number="2.1.1.152"
                     /GO_function="GO:0043819 - precorrin-6A synthase
                     (deacetylating) activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629628.1"
                     /locus_tag="AORI_RS50105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1819"
                     /product="precorrin-6A synthase (deacetylating)"
                     /protein_id="WP_016332211.1"
                     /sec_met_domain="TP_methylase (E-value: 5.5e-25, bitscore:
                     87.4, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKISAIGIGAGDPDHLTVQAIRRLNETDVFFVLDKGSEKQDLVA
                     LRQEILDRFVEQPGYRVVRAPDPERDRTPDDYRKAVADWHRLRTDVYENMIASLGPDER
                     GAFLVWGDPALYDSTLTLLDAVLDRGNVEFEYDVIPGVSSVAALTSRHRTTMNQIGRPV
                     LVTTGRRLEAGWPADVDDVFVMLDAGCTFSRFVDTGLEIYWGAYLGTPDELLLSGPLTA
                     DLAEEIRSVRASARSRKGWIMDIYHLRRPAPSRI"
     misc_feature    1199..1214
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     misc_feature    1199..1215
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: medium, score: 26.96"
                     /tool="antismash"
     misc_feature    complement(1200..1215)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: medium, score: 27.98"
                     /tool="antismash"
     gene            1261..1467
                     /locus_tag="AORI_RS50110"
                     /old_locus_tag="AORI_1820"
     CDS             1261..1467
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629627.1"
                     /locus_tag="AORI_RS50110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1820"
                     /product="heavy-metal-associated domain-containing protein"
                     /protein_id="WP_016332212.1"
                     /transl_table=11
                     /translation="MAETTYTVKGMSCGHCASSVTEEVSGIAGVSAVNVDVASGKVTVT
                     SEAPLDVQAVDAAVTEAGYQLVS"
     gene            1464..1625
                     /locus_tag="AORI_RS83835"
     CDS             1464..1625
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629626.1"
                     /locus_tag="AORI_RS83835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167337762.1"
                     /transl_table=11
                     /translation="MSTAVKVSAFAAALVAVFAVAWAIGSAVGPLDEEPPPPAPASEHH
                     GHHPGGTP"
     gene            1622..3850
                     /locus_tag="AORI_RS50115"
                     /old_locus_tag="AORI_1821"
     CDS             1622..3850
                     /EC_number="7.2.2.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007035447.1"
                     /locus_tag="AORI_RS50115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1821"
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_016332213.1"
                     /transl_table=11
                     /translation="MTSQRVELAIGGMTCASCAARVERKLNKVDGVSATVNYATEKAQV
                     DFPTAVSVEDLVGVVESAGYTAQPPKPDEDAEQTGSLRTRLVVSAVLAVPVIVLAMVPA
                     WQFTYWQWVSLALAAPVVTWGAWPFHRPAWTNLRHGAATMDTLISLGVVAATLWSLYAL
                     LFGTAGTPGMRHGFELTMERGHGAGNVYLEVAAGVTTFLLAGRYFEARSKRRSGAALRA
                     LLELGAKDVALLKDGIESRVPIGELRTGDEFVVRPGEKVATDGVVTDGGSAVDLSMLTG
                     EAVPVEVVAGDAVVGGTVNASGRLVVRATRIGADTQLAQMARLVEDAQNGKARVQRLAD
                     RVSAVFVPVVIALAVGTLGFWLGAGSGADAAFTAAVAVLIIACPCALGLATPTALLVGT
                     GRGAQLGILIKGPEVLESTRAVDTVVLDKTGTVTAGKMSLTDLFGEDETEVLRLAAAVE
                     HHSEHPIARAIVAAAEERLGELPQAGGFRNVEGLGVVGEVEGKTVLAGRSALLDQHGIA
                     VGDEFAQVKKVAEERGATAVVVAWDGETRGVVVVADTVKPTSAEAVAGLKALGLRPVLL
                     TGDNAGSAAAVAAEVGIDEVIAEVLPAGKVDVVKRLQAEGRVVAMVGDGVNDAAALAQA
                     DLGLSMGTGTDAAIEAGDLTLVRGDLRAAVDAIRLARRTLGTIKGNLFWAFAYNVAALP
                     LAALGLLNPMIAGAAMAFSSVFVVTNSLRLRRFRTGPAGRWRRTPPGP"
     gene            complement(3801..4082)
                     /locus_tag="AORI_RS50120"
                     /old_locus_tag="AORI_1822"
     CDS             complement(3801..4082)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003089374.1"
                     /locus_tag="AORI_RS50120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1822"
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="WP_007034631.1"
                     /transl_table=11
                     /translation="MTGYGTEREAYLKRLRRIEGQIRGLQRMVEEDKYCIDILTQVSAA
                     TKALQSFSLELLDEHLATCVVHAAAAGGEEADLKVREASDAIARLVRS"
     cand_cluster    3880..49699
                     /SMILES=""
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    3880..49699
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[23879:29699](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      23880..29699
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     gene            4251..4613
                     /locus_tag="AORI_RS50125"
                     /old_locus_tag="AORI_1823"
     CDS             4251..4613
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154207.1"
                     /locus_tag="AORI_RS50125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1823"
                     /product="YciI family protein"
                     /protein_id="WP_016332214.1"
                     /transl_table=11
                     /translation="MKYMIMITMNPTAWDALPEEERDEVVARIDPFMKKLTESGELLGT
                     QALAEPKESTVVRVRDGVPVVTDGPFAESKEYLAGFYLVECDSKERAIEIAGQIPDAHV
                     NAMEIRPVVFSSGDNA"
     gene            complement(4614..5282)
                     /locus_tag="AORI_RS50130"
                     /old_locus_tag="AORI_1824"
     CDS             complement(4614..5282)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034633.1"
                     /locus_tag="AORI_RS50130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1824"
                     /product="hypothetical protein"
                     /protein_id="WP_016332215.1"
                     /transl_table=11
                     /translation="MEMPGFDLAWRGFNRAQVREFVREVEAELRRVEAERDEAIRRGQV
                     LAGELAATQEENRELKASVDRISRVPIAPDALQERSRRMLELTREEADDIAARAAEEAA
                     KAEEERKRVAEDFERAMTLRRAEAMRALAARDEAAQAKARKLLDDAAEEAERLVAEARQ
                     KADVALRLRDDVLKQLAGCRELLTEAGVVLAVPDSPKPEVPVQRRSRPEARTGTEAAAT
                     "
     gene            5450..6190
                     /locus_tag="AORI_RS50135"
                     /old_locus_tag="AORI_1825"
     CDS             5450..6190
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034634.1"
                     /locus_tag="AORI_RS50135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1825"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_228688325.1"
                     /transl_table=11
                     /translation="MGEWTTIAYPTGGGRVTSSRIRVPGWNTATAAEGYRQVRENIAIL
                     VTDHAGAGERAVPACPQWTVRDLIAHLTEICDRVITRFGGEACPIPESASAVELLKLWL
                     ERGPEADTLLAADGDGKSRGDIMVMDAFTHELDIRYALGAPPPEAHAAWLRGFEVLVSG
                     LGASLGRHGLPGLRIETEGATWIAGTEPVAAVLSGAPADLYRTLAGRRSPAQITAMDWL
                     GDPGPWLRAFTWGPFTPPEAEIER"
     gene            complement(6191..7525)
                     /locus_tag="AORI_RS50140"
                     /old_locus_tag="AORI_1826"
     CDS             complement(6191..7525)
                     /GO_component="GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154202.1"
                     /locus_tag="AORI_RS50140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1826"
                     /product="copper resistance protein CopC"
                     /protein_id="WP_043847968.1"
                     /transl_table=11
                     /translation="MTGRLCALLALVAAWFGVAVLTAAPASAHVELLSSNPADGARLTS
                     APARVSITLSENIGIQPNSIKVVDQQGTDVVSGPVFQPGEVAEEVAVALEPDLPDGSYL
                     VEYAFVSTDSHPVRGTIAFVIGTGPLITSAGAVSASTGTDPVTDALFTTFRWGSFGGVA
                     LLGGLVFLVVCRPGGRADPAARKLITAGLWLSGVTAVAGFLLQGPYVAGRGVGAVFDGA
                     LIEATLRVAYGKLLLLRLAAIVALAVIVRRLLAGDLPDRLRSRYENLGIAAGFIVMLSF
                     SATGHAVADKIMFLSVSADLAHFGAMAVWVGGLIQLAVLLRGRYSASEAEPALARFHPI
                     ATRSIVIMVVSGAYLGFRLVPSVEALWTSAYGIVFVLKLTGFAALLLVANLSRTAVRRG
                     ISGRGGTGVVTADLRKLRVSVGVEVLIVAVVLALAAALSSMSPAG"
     gene            complement(7522..8100)
                     /locus_tag="AORI_RS50145"
                     /old_locus_tag="AORI_1827"
     CDS             complement(7522..8100)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332218.1"
                     /locus_tag="AORI_RS50145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1827"
                     /product="hypothetical protein"
                     /protein_id="WP_016332218.1"
                     /transl_table=11
                     /translation="MAALDSPRPGLLASLNGKYHRAALLTFAVVVVAHWAEHLVQAFQI
                     YALGWKTPDARGVLGIPFPKLISSEWLHYGYAIVMLIFLFALRKGFAGRSRQWWNLALG
                     LQFWHHIEHLLLLIQAQTGWRLGGGTAPSSIIQLFIPRVELHLFYNTIVTIPMIIAMLV
                     HRKASAAERELTGCTCSPVSRRELATAAS"
     gene            complement(8217..8903)
                     /locus_tag="AORI_RS50150"
                     /old_locus_tag="AORI_1828"
     CDS             complement(8217..8903)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034637.1"
                     /locus_tag="AORI_RS50150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1828"
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="WP_016332219.1"
                     /transl_table=11
                     /translation="MSSRTYGQFCGLARALEIIGERWSLLIVRDLVLGPKRFTELQAGL
                     PKIPASTLSARLNELEQSGVLRRRLLPQLDAAVVYELTEYGSELDQIVLDLGLWGARSL
                     GQPAAEDVFTLDSAILSLYTTFRSEKAKGVQVTYELRYPGEMVLHAIVEDGALKVAEGA
                     HPGADAVIEPLGPFIKDLLSGDLAAADATRTGKIRIEGDFEYLELFTELFHIPAAPKMS
                     DGIVVR"
     gene            complement(8938..9777)
                     /locus_tag="AORI_RS50155"
                     /old_locus_tag="AORI_1829"
     CDS             complement(8938..9777)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629618.1"
                     /locus_tag="AORI_RS50155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1829"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_016332220.1"
                     /transl_table=11
                     /translation="MYTGSRVADKHHGSAPNPIPAASASPVRFSLLGPLELVRDGIDYA
                     PTTPKLLQVLAMLVMSPGKIVHIDTIVQELWANDPPRSVRTTMHTYVYQLRKCIDENEL
                     APYGETMLATKPPGYVFRIAPEQVDVFEFQELQHKGRELHLRGEHTEAAKAFRSALDLW
                     SGPPLANVHCGPVLSAYAVDLVEQRRSTLHLRIEADIAAGMRHELIGELRSLVTANPLD
                     EALHGQLIRVLGRSGRRSDALATYRQVRARLNNELGVEPCDELQVLHHDLLSEGEPA"
     misc_feature    9899..9912
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            10001..12271
                     /locus_tag="AORI_RS50160"
                     /old_locus_tag="AORI_1830"
     CDS             10001..12271
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154196.1"
                     /locus_tag="AORI_RS50160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1830"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_016332221.1"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 2.8e-23,
                     bitscore: 80.7, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 8.8e-20,
                     bitscore: 69.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 5.3e-14, bitscore:
                     50.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 9e-06, bitscore: 24.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03882 (E-value: 1.1e-44, bitscore:
                     151.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 4.8e-92, bitscore: 308.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.8e-78, bitscore:
                     262.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREASTTPTSIGGLGFKRHLRAEISEGNGAYLFSEQGVIAIRGAQ
                     VASVAALLDGTRDLDGLLSACPEGMNAEQVTGVVARLVEAGLVTVRVPDEFSGDERALA
                     YWDACGLDASAVACRQKPATASLTAIGRGVDTSQVANALAASGIEVVETASELAIVLCD
                     DYLDPRLAGIDAEHRRTGRPWLLARPSGSQVWIGPIMQPGRSGCWHCLTNRLWGHRHAE
                     ACVQEVLGHDGPASFPMPAVPPLTAAASHLISLEASKWLAGHRYPGQQAVWILDTLDLQ
                     GRLHELRRRPQCPECGDEGIVAAQTAEPVVLREAKKATSGGGGHRTLTPVEVLDRYGHL
                     VSPVTGIVKEIARDPRAPAFVNAYRSGLNVARRVRGEAGLQAGLRGDNGGKGASPIDAE
                     VGALCEAIERFSANYQGDELRIRDTFRALGDDAVHPNTCMLFDERQYETRVDWNARHAN
                     FQHVPDRFDTEAAVDWTPLWSLSQQRRKLMPTAYLYYGVPPECGLTGMRADSNGCAAGS
                     SVEDAILQGLLELVERDAVAMWWYNRLPVPGVDIASFDDPWAEEMVGQYARAGRELWVL
                     DLTADLGVPVMVALSRSIAGPRENVMMGFGAHLDPRTALRRAVSELNQMIPAVLANDVE
                     LDDPDASAWLKYATVGNQPYLLPAPGRSAKRAADFKFVRRPDVRDDVECLVRKLSALGM
                     ETLVLDQTRPDIDLPVVRVVVPGLRPFWSRFAPGRLFDVPVRLGRLAEPTPYDRLNPFP
                     MFL"
     aSDomain        10037..10267
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AORI_RS50160_Cyanobactin_D_RRE.1"
                     /evalue="9.60E-26"
                     /identifier="RREFam007.1"
                     /label="AORI_RS50160"
                     /locus_tag="AORI_RS50160"
                     /protein_end="89"
                     /protein_start="12"
                     /score="80.7"
                     /tool="antismash"
                     /translation="GLGFKRHLRAEISEGNGAYLFSEQGVIAIRGAQVASVAALLDGTR
                     DLDGLLSACPEGMNAEQVTGVVARLVEAGLVT"
     aSDomain        10040..10318
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AORI_RS50160_NHLP_CD_RRE.1"
                     /evalue="1.80E-16"
                     /identifier="RREFam015.1"
                     /label="AORI_RS50160"
                     /locus_tag="AORI_RS50160"
                     /protein_end="106"
                     /protein_start="13"
                     /score="50.9"
                     /tool="antismash"
                     /translation="LGFKRHLRAEISEGNGAYLFSEQGVIAIRGAQVASVAALLDGTRD
                     LDGLLSACPEGMNAEQVTGVVARLVEAGLVTVRVPDEFSGDERALAYW"
     aSDomain        10040..10333
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AORI_RS50160_Goadsporin_CD_RRE.1"
                     /evalue="3.00E-22"
                     /identifier="RREFam013.1"
                     /label="AORI_RS50160"
                     /locus_tag="AORI_RS50160"
                     /protein_end="111"
                     /protein_start="13"
                     /score="69.6"
                     /tool="antismash"
                     /translation="LGFKRHLRAEISEGNGAYLFSEQGVIAIRGAQVASVAALLDGTRD
                     LDGLLSACPEGMNAEQVTGVVARLVEAGLVTVRVPDEFSGDERALAYWDACGL"
     misc_feature    12266..12268
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12314..13759
                     /locus_tag="AORI_RS50165"
                     /old_locus_tag="AORI_1831"
     CDS             12314..13759
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034640.1"
                     /locus_tag="AORI_RS50165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1831"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_016332222.1"
                     /transl_table=11
                     /translation="MAETIPLWSLTDDSLVEIGEDGSLVVVTRWGEYEFDRAEPLVLES
                     LRRMALGPVSLANVTSSWEPFEREPDLEGELSWTAEGADALRQVLKELGGSVVRSLGLA
                     DGRGPLLSVIPVVLAPVFAPVEIPPTRPIRLSRFSSLRSDADGMGLESPSARYRVVLSQ
                     PWAVHVAATLATAKSVRDIVSTTGIDASVAGAIVSYLVAAGVVQVAGEDGRFAEDDDPE
                     LSLWSPDELSFHTTSRTWRPGGPADLPGLGKPPVVKAATGEGPVHPLYRPDLADRAVTD
                     PTLTTLLENDHTCPEFTEGVLTAEQIGEFLFRGARIRSIGPAHLPNGPAHSASQRPYFS
                     VACLYELELYVSVNRCSGLDRGIYHYDPLEHRLALVNADEADLDAMLDMAMIGGGNHRR
                     PSALITVTARMPRMASVLGGGAYATTLAHVGALQQTLYLVARAMGLAAHAVPVDAGDRV
                     DRALKLDWPAEVSVGECVLDLPV"
     misc_feature    complement(12315..12329)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 20.47"
                     /tool="antismash"
     gene            14016..14897
                     /locus_tag="AORI_RS50170"
                     /old_locus_tag="AORI_1832"
     CDS             14016..14897
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034641.1"
                     /locus_tag="AORI_RS50170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1832"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_016332223.1"
                     /transl_table=11
                     /translation="MAANEKGVTEPGRLPEPASPLQPAVLQAISSMHARYFDPITLGDL
                     ASEVFVSPFHFSRIFTKATGITPGRYLTAIRLFEAKRLLLTTSLTVSDIVCSVGYSSVG
                     TFTSRFTRAVGMTPTQYRDPEVGELLVALAPHFQRLPTLEALHSAGMGSATMRSGTGTI
                     SVRVETPRGAGPASVLIGLFAESIPQCGPVAFGGRANVLSADIEIQNVPEGRWTVIGVA
                     EHAAGTAASSFSVGTLPGRVDITRYGRVHLRMPMRAPRPTDAPMAITLAGGPSSAGNRM
                     TMPAPEYLRAVA"
     gene            15057..16010
                     /locus_tag="AORI_RS50175"
                     /old_locus_tag="AORI_1833"
     CDS             15057..16010
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645503.1"
                     /locus_tag="AORI_RS50175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1833"
                     /product="DUF1702 family protein"
                     /protein_id="WP_267283979.1"
                     /transl_table=11
                     /translation="MRRRMITPDVSETSLDKRGFHKKSPAAQELLETVGEKFLLGYAHA
                     VEARSVEQAEEWLEQIPVKYRGFAYEGAGMGYGMLDGLPGGGRRHVERFLDGPGEKHDY
                     IIYVGVGWAMARLPRFRWPSAEDFDPLLRWLVLDGYGFHQAYFKTAKYVDGQFQDPDFS
                     WPPGNDGYALRAIDQGIGRALWFICGTDVDLVADTVARFPERRHGDLYAGIGLASTYAC
                     GVTGDELLKLAEFAGEHRGNLAQGSAFAAEARVRAGLLIPETEVATRAICGLPAERAAA
                     ITQEVRPATVVDGELPAFETWRQRIAEAILSGGAGK"
     gene            16007..17971
                     /locus_tag="AORI_RS50180"
                     /old_locus_tag="AORI_1834"
     CDS             16007..17971
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629613.1"
                     /locus_tag="AORI_RS50180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1834"
                     /product="CRTAC1 family protein"
                     /protein_id="WP_016332225.1"
                     /transl_table=11
                     /translation="MTATLGWLRKQLAGIVALVLMAGLFVVAQLPTVSTAEADTMASKY
                     AFEPLTIALPEAAKSQSIRTVNKEYEHIRAWISSVGAAIAVNDLDGDKLANDLCFVDPR
                     SDQVVITPTPGKGGDRYAPFALDAAPLPMGKYIAPMGCVPADYNEDGRVDLLAYYWGRT
                     PILFLSKPGATKLEPKAYEPVELVPGNNSKNGEYSGPLWNTNAASVGDFDGDGHQDIFI
                     GNYFPDSAVLDDRVSGGVEMNKSMSHADNAGGKYILRFTGATQGAKPSATFALDDKAIP
                     ADSQGGWSLAASATDVDGDNLPELYIGNDFGHDRLLYNKSRPGHVEFAEVKGIRGPNEP
                     KSKVIGNDSFKGMGVDFADLDHDGLYDLYVSNITTSWGIEESHFQFMNTAKDTADLRGR
                     LQGGEAPWVDRSAQAGTAWSGWGWDVKIADYDNSGESVITQATGFVKGDVNRWPQLQEL
                     ATSNDELLKHPYFWPNMVAGDDVGGDHTLHFWAKSSDGRYTDLAPRLGLAVPVPTRGIA
                     TGDADGDGKLDFAVARQWEQPIFYRNVSPGTGSYLNLKLVHDKASADGPLKAAGTAAIG
                     AQVTVVTPDGKKYMDRVDGGSGHSGKRSHEIQIGLGKVTGPVKVCLQWRDLTGQIRTQE
                     VQLTPGDHTFQLGAQAKEK"
     gene            17977..18957
                     /locus_tag="AORI_RS50185"
                     /old_locus_tag="AORI_1835"
     CDS             17977..18957
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154188.1"
                     /locus_tag="AORI_RS50185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1835"
                     /product="hypothetical protein"
                     /protein_id="WP_043848641.1"
                     /transl_table=11
                     /translation="MAEQTLTAPKSNKTITALRRFAISITIFNIIGYTVLGFEQPYTYP
                     FIALATAYATEILLEIIGARAQGRGVRFRGNGFKGLVEFLFPAHITGLALNMLTYVNDQ
                     VLVMMFGVVVAVGAKWVLQAPVRGRLRHYMNPSNFGITIILLVFPWASIAPPYHFTEQV
                     DSWVGWLIVGIIIVSGTVLNAMLTQRMWLIGAWLITFALQAIIRGLVFDTAIPGALGMM
                     TGVAFVLYTNYMVTDPGTTPSKPASQILFGSGVALAYGFFMVVHVAYGLFLATALVCLI
                     RGMFLWGLHFSKKATEKWEAEQAKSAEITSLPKPAEKPETGAVAA"
     gene            18954..20306
                     /locus_tag="AORI_RS50190"
                     /old_locus_tag="AORI_1836"
     CDS             18954..20306
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034645.1"
                     /locus_tag="AORI_RS50190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1836"
                     /product="cytochrome P450"
                     /protein_id="WP_016332227.1"
                     /sec_met_domain="p450 (E-value: 1.5e-87, bitscore: 293.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPGAESSRAARLAPPGPPRRATFGLLKKLFTDRLALMSDSAEAH
                     GDVVRIAIGPKTMYLVNHPELAKHVLADNAANYHKGIGLQEARRALGDGLLTSDGDVWK
                     KQRRTIQPVFQPKRIARQASVVANEVEGLVKRLRDTEGPVEILHEMTGLTLGVLGKTLL
                     DADLGGFTSLGHSFEAVQDQAMFEAVTLSMVPQWAPLKKQLRFRESRDDLRRIADELVE
                     QRLANPVENGEDVLSRLIATDGTRGQMRDELITLLLAGHETTASTLGWAFHLLDEHPEI
                     AAKLRAEADAVLGDQLPTHEDLHRLPYTARVVEEVMRLYPPVWLLPRVAQADDEIGGYH
                     IPAGSDVVVVPFTLHRHPDFWPEPERFDPDRFDPDRPSGRPRYAYIPFGAGPRFCIGNS
                     LGVMEAVFVLTMVLRDLELRKLPGYDVVPEAMLSLRVRGGLPMTVHTRNRR"
     gene            20312..20869
                     /locus_tag="AORI_RS50195"
                     /old_locus_tag="AORI_1837"
     CDS             20312..20869
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332228.1"
                     /locus_tag="AORI_RS50195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1837"
                     /product="DUF5987 family protein"
                     /protein_id="WP_016332228.1"
                     /transl_table=11
                     /translation="MDSDEQVEVSTLEAYADTIVPGEKRFPGDHAIAGASPGPGAVAAG
                     ALELLHTEATGVTVGLPYLAQSLNDHAKVYAKEHDITLDESLPAFVALSFADRTALVRS
                     LTAPGHPEKDGWVSLALFCNMSFDSAAHKHTAEAIAEGHPGLLAMGYTAPDEDGLWRFP
                     KFSYRRELARVHPDTTPSGSPA"
     gene            20866..22518
                     /locus_tag="AORI_RS50200"
                     /old_locus_tag="AORI_1838"
     CDS             20866..22518
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629609.1"
                     /locus_tag="AORI_RS50200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1838"
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_016332229.1"
                     /transl_table=11
                     /translation="MTAYDKTDVVIVGSGFGGSIPAYHLAAGGAKVTVLERGPWLETKE
                     FEHDYLLGSSYTRAFDFVVGDGMSVLGGNCVGGGSVVYFAAMPRAPKFVFERHGSIGRR
                     MWPSVLTRDTLEPWYDRVSESLPVSTQDWNDVSYAGGLWAAFCNHSGRTANPAPVAVDN
                     DRCVNCNFMMAGCRFDAKRSLLTNYLPAALAHGAKIRPLHEVQRIERIDDGDYRVHFNI
                     VDDEDYRLQSGSGTIDAKIVIIAAGAGATPVILQRSEAALGTMPHAVGRYFSGNGERLN
                     TAIINEERVREVLGLSREDGKVYEANHIGKGPTVANWDKLDGSLPEYERYSLEQLYFPP
                     GLGTILAQVPDGDEPRWFGVQKKEILKKWASWLTIFLMTEDDNEGVFGAPPPTGNAYRI
                     SQQMLGRGPLKYDPTPNTRHGWALADAECKEILEKDGLAKVAPWTNDVVGAYTVHPLAS
                     CRIGDDPATSALHPNHELRDHPGIFVTDSASVPGALTVNPAMTIAALAERSVPGIVRAL
                     QARGVDVTYGAPAPDGSITGRRAVGKLSLVAGS"
     gene            22521..23471
                     /locus_tag="AORI_RS50205"
                     /old_locus_tag="AORI_1839"
     CDS             22521..23471
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629608.1"
                     /locus_tag="AORI_RS50205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1839"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_016332230.1"
                     /transl_table=11
                     /translation="MAPVLVKLALRRAVREARYVRPVPFGRATGLVRDVYGRLERDFGM
                     LAPPVAVHSPSPPVLAASWVMLRESLVAAGETSRADREIVATVVSRGNSCPYCVEVHGM
                     ALDSLGRSVEAAAIASGRPVTDPRTGILSAGARAELTAVAFTFHYLNRVVSVFLGPSPL
                     PSSVPDSARAKAKAVLGRFLRPVTGAAPGESLDLLPVGSRDFAWAAGNPVVEDAFSRAA
                     SAFAALPVPSSVRDVVERELSTWDGAPPGLSRSWVEAFDDPAVRLALVVAKAPYQVDDA
                     LVAAAGLGDRELVELVGWAGFTAAARAVSVAPLPG"
     gene            23880..29699
                     /locus_tag="AORI_RS50210"
                     /old_locus_tag="AORI_1840"
     CDS             23880..29699
                     /EC_number="6.4.-.-"
                     /GO_component="GO:0034081 - polyketide synthase complex
                     [Evidence IEA]"
                     /GO_process="GO:0030639 - polyketide biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Enediyne-KS) (5-465). E-value:
                     3.3e-99. Score: 324.6. Matches aSDomain:
                     nrpspksdomains_AORI_RS50210_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (620-848). E-value: 3.5e-57.
                     Score: 186.0. Matches aSDomain:
                     nrpspksdomains_AORI_RS50210_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1209-1390). E-value: 1.3e-32.
                     Score: 105.1. Matches aSDomain:
                     nrpspksdomains_AORI_RS50210_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_DH (1461-1604). E-value: 2.2e-10.
                     Score: 33.1. Matches aSDomain:
                     nrpspksdomains_AORI_RS50210_PKS_DH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154183.1"
                     /locus_tag="AORI_RS50210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1840"
                     /product="type I polyketide synthase"
                     /protein_id="WP_016332231.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 5.6e-55, bitscore:
                     185.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 9e-257, bitscore: 850.8,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.7e-55, bitscore: 186.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVERISIVGIGLRYPDAGSPEELWENVLAGRRAFRRLPDERMNR
                     EDYYSPDPKAPDRFYAQKAAVLRDYEFDRIKYKVAGSTFRSTDTTHWLALDVAAQALAD
                     AGFPEGEGLPKPATGVVIGNSLTGEFSRANIMRLRWPYVRRTVAAALAERGWADGDTAE
                     FLHDLEAQYKAPFPEIDEDTLAGGLANTIAGRVCNFFDFGGGGFTVDGACSSSLLSVVT
                     AANALSEGDLDVAIAGGVDLSIDPFEVIGFAKTGALAKREMKVYDADSNGFWPGEGSGM
                     LVLMREEDAIAQGKRIYATIGGWGVSSDGKGGITRPEASGHRLALKRAYDKAGYGVETV
                     SYFEGHGTGTALGDATEIEALSTARRDADPLAERAALSTIKGNIGHTKAAAGVAGLIKA
                     TLAVYHQVIPPATGHFEPHESLVGDSARMYVPAEAGLWPSDQPVRAGVSAMGFGGINSH
                     VTVTEAPGAARRKELDERTRSLVAGRQDSELLLLDADDAASLRGKVTGLLEVVPKLSFA
                     ELADLAGTLSAELSGKPVRAAVVAAGPDDAERKLAKLLDLLGEGEPEVFSAKEGIFAGS
                     RSQSPKIGFLFPGQGSGQGRVGALRKRFAHADDIYRAANLSTGADQVATDVAQPRIVTG
                     SLAGLRVLKSLGIEAATVTGHSLGELTALHWGGALTEREVLKLAKIRGKVMATASDGDG
                     AMAAIAATPSVAEGLAEGEEVVIAGYNAPEQTVLSGPAEAIDRVVARARAEGVTAARIN
                     VSHAFHSPAVVPAAEAMTGELAAIDFARLDRPVVSTVTGDVLHAAEDLRDLLRDQVVLP
                     VRFREAAAKVAERSDLVIEVGPGRVLTGLLGTIAPGTPVLSIDTDSLTLAPVLKVAGAA
                     FAFGAQLETSTLFDGRVVRALPADGEFSFLASPCEAAPSIGAVLTRDRVAEPAEAAAGT
                     ASESGGSSTLDLLRKLASERVELPLEAVTADTHPLDDLHLSSITVGQLVNDVTRALGRP
                     ALEGMPNFATVCLGELAEMIDELAQTAKPADSNQAEVAGVGPWVRPFAVEYVVAPKPSP
                     DLATGISTAEWTAFAPAGHPLAEPLRAALATAGVGDGVLLCLNADSASGDVGLFLDAGR
                     AVLAAPNGTRFVVVQHGLGASGLAKTLRLEDPSARTTIVDLADLGPVDPEALDAAVSTV
                     VTEVAATTDFSEVRYDTAGVRTVPKLAALTPAEAEGTPLDTGDVLLVTGGGKGITAESA
                     LALAKDSGAKLALLGRSDPADDAELSENLGRMAAAGITYRYERADVTDGRQVADAIGRV
                     QAEFGPVTAVLHGAGRNEPAALFSLTEESFRKTLAPKIGGLNAVLDAVDKDKIKLLVTF
                     GSIIGRAGLRGEAHYATANDWMTELTVRFGQEHPRAKAIALEWSVWSGTGMGEKLGVVS
                     ALMRDGITPIPTEEGIEILRQVVGDPAAPSVLVVCGRTAGLATLPVEKRELPLTRFVDR
                     AVVHYPGVELITEADLSAGSDPYLADHLLDGQLLFPAVIGMEAMTQVAKAALAAETLPA
                     PVFSDVEFLRPIIVSPGGSTTIRLAALARDAETVDVVLRSGETGFSADHFRARLSFSRP
                     DPLGDTVARDVALPPVPVDPTTELYGTVLFQGKRFQRVTGYRRASARHAVAEVATGAEV
                     DWFAPFLPQEQLLADPGTRDAMMHAIQCCVPDATLLPQGIERLYLAEPGEQHPEYVLLD
                     ARERSQDGDSYVYDLDVRNPDGKLVERWEGLKLRAVRKRDGEGPWVPSMLGSYLERSVE
                     RLLGSSRAIVVEPDPVGVPVETTPERRAQTALAAGRAVDAPLEIRYRPDGKPEADGVEV
                     SASHSADLTLAIAGAGRIACDVETAIERTPEDWAGLLGEDLLAVGELLAADAREPLSVA
                     HTRVWSALECVRKTGDMTQALTVHRVDPDGWAVLSHGGARIATWVTTVNDRTDPVVFAV
                     LQGEES"
     aSDomain        23895..25274
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AORI_RS50210_PKS_KS.1"
                     /domain_subtypes="Enediyne-KS"
                     /evalue="3.30E-99"
                     /label="AORI_RS50210_PKS_KS.1"
                     /locus_tag="AORI_RS50210"
                     /protein_end="465"
                     /protein_start="5"
                     /score="324.6"
                     /tool="antismash"
                     /translation="ISIVGIGLRYPDAGSPEELWENVLAGRRAFRRLPDERMNREDYYS
                     PDPKAPDRFYAQKAAVLRDYEFDRIKYKVAGSTFRSTDTTHWLALDVAAQALADAGFPE
                     GEGLPKPATGVVIGNSLTGEFSRANIMRLRWPYVRRTVAAALAERGWADGDTAEFLHDL
                     EAQYKAPFPEIDEDTLAGGLANTIAGRVCNFFDFGGGGFTVDGACSSSLLSVVTAANAL
                     SEGDLDVAIAGGVDLSIDPFEVIGFAKTGALAKREMKVYDADSNGFWPGEGSGMLVLMR
                     EEDAIAQGKRIYATIGGWGVSSDGKGGITRPEASGHRLALKRAYDKAGYGVETVSYFEG
                     HGTGTALGDATEIEALSTARRDADPLAERAALSTIKGNIGHTKAAAGVAGLIKATLAVY
                     HQVIPPATGHFEPHESLVGDSARMYVPAEAGLWPSDQPVRAGVSAMGFGGINSHVTVTE
                     AP"
     aSModule        23895..28691
                     /domains="nrpspksdomains_AORI_RS50210_PKS_KS.1"
                     /domains="nrpspksdomains_AORI_RS50210_PKS_AT.1"
                     /domains="nrpspksdomains_AORI_RS50210_PKS_KR.1"
                     /domains="nrpspksdomains_AORI_RS50210_PKS_DH.1"
                     /incomplete
                     /locus_tags="AORI_RS50210"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       24903..24950
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AORI_RS50210_0001"
                     /evalue="9.30E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="AORI_RS50210"
                     /protein_end="357"
                     /protein_start="341"
                     /score="9.0"
                     /tool="antismash"
                     /translation="YFEGHGTGTALGDATE"
     aSDomain        25740..26423
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AORI_RS50210_PKS_AT.1"
                     /evalue="3.50E-57"
                     /label="AORI_RS50210_PKS_AT.1"
                     /locus_tag="AORI_RS50210"
                     /protein_end="848"
                     /protein_start="620"
                     /score="186.0"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="DQVATDVAQPRIVTGSLAGLRVLKSLGIEAATVTGHSLGELTALH
                     WGGALTEREVLKLAKIRGKVMATASDGDGAMAAIAATPSVAEGLAEGEEVVIAGYNAPE
                     QTVLSGPAEAIDRVVARARAEGVTAARINVSHAFHSPAVVPAAEAMTGELAAIDFARLD
                     RPVVSTVTGDVLHAAEDLRDLLRDQVVLPVRFREAAAKVAERSDLVIEVGPGRVLTGLL
                     GTIAPG"
     CDS_motif       25818..25940
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AORI_RS50210_0002"
                     /evalue="7.30E-09"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="AORI_RS50210"
                     /protein_end="687"
                     /protein_start="646"
                     /score="27.6"
                     /tool="antismash"
                     /translation="GIEAATVTGHSLGELTALHWGGALTEREVLKLAKIRGKVMA"
     aSDomain        27507..28049
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AORI_RS50210_PKS_KR.1"
                     /evalue="1.30E-32"
                     /label="AORI_RS50210_PKS_KR.1"
                     /locus_tag="AORI_RS50210"
                     /protein_end="1390"
                     /protein_start="1209"
                     /score="105.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="VLLVTGGGKGITAESALALAKDSGAKLALLGRSDPADDAELSENL
                     GRMAAAGITYRYERADVTDGRQVADAIGRVQAEFGPVTAVLHGAGRNEPAALFSLTEES
                     FRKTLAPKIGGLNAVLDAVDKDKIKLLVTFGSIIGRAGLRGEAHYATANDWMTELTVRF
                     GQEHPRAKAIALEWSVWS"
     CDS_motif       27513..27605
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AORI_RS50210_0003"
                     /evalue="7.00E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="AORI_RS50210"
                     /protein_end="1242"
                     /protein_start="1211"
                     /score="15.5"
                     /tool="antismash"
                     /translation="LVTGGGKGITAESALALAKDSGAKLALLGRS"
     CDS_motif       27897..27983
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AORI_RS50210_0004"
                     /evalue="4.80E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="AORI_RS50210"
                     /protein_end="1368"
                     /protein_start="1339"
                     /score="19.1"
                     /tool="antismash"
                     /translation="LVTFGSIIGRAGLRGEAHYATANDWMTEL"
     aSDomain        28263..28691
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AORI_RS50210_PKS_DH.1"
                     /evalue="2.20E-10"
                     /label="AORI_RS50210_PKS_DH.1"
                     /locus_tag="AORI_RS50210"
                     /protein_end="1604"
                     /protein_start="1461"
                     /score="33.1"
                     /tool="antismash"
                     /translation="AVVHYPGVELITEADLSAGSDPYLADHLLDGQLLFPAVIGMEAMT
                     QVAKAALAAETLPAPVFSDVEFLRPIIVSPGGSTTIRLAALARDAETVDVVLRSGETGF
                     SADHFRARLSFSRPDPLGDTVARDVALPPVPVDPTTELY"
     CDS_motif       28329..28376
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AORI_RS50210_0005"
                     /evalue="1.30E-03"
                     /label="PKSI-DH_m2"
                     /locus_tag="AORI_RS50210"
                     /protein_end="1499"
                     /protein_start="1483"
                     /score="11.4"
                     /tool="antismash"
                     /translation="YLADHLLDGQLLFPAV"
     gene            29701..30141
                     /locus_tag="AORI_RS50215"
                     /old_locus_tag="AORI_1841"
     CDS             29701..30141
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154182.1"
                     /locus_tag="AORI_RS50215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1841"
                     /product="acyl-CoA thioesterase"
                     /protein_id="WP_005154182.1"
                     /sec_met_domain="4HBT_2 (E-value: 1.1e-12, bitscore: 47.3,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADYYEILHTVGFEETNLVGNVYYVNYVRWQGRCREMFLKEKAPA
                     VLEEVRHDLKLFTLKVDCEFYAEITAFDELSIRLRLEELTQTQIQFTFDYVHLTAEGER
                     LVARGRQRIACMRGPNTATVPSRVPEQLREALAPYAVDGKGE"
     gene            30143..30715
                     /locus_tag="AORI_RS50220"
                     /old_locus_tag="AORI_1842"
     CDS             30143..30715
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154181.1"
                     /locus_tag="AORI_RS50220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1842"
                     /product="flavin reductase family protein"
                     /protein_id="WP_016332232.1"
                     /transl_table=11
                     /translation="MGTLEEPSRPVLKRLPAPVARRRLSAQAGLREVMGQFATGVTVLT
                     AGGERAHGMTANAVTSVSLEPPMVLCCVSRAARMHEAIVTAGSYAVTVLASDQKDLAKY
                     FADWRRPAGIAQFDSVDWTAGPQTGAPLLDGALAWLECELAEVYEGGDHSIFLGKVVAS
                     CRGTAQDSLVFYSGGYHQIDGRIRASA"
     gene            30733..30900
                     /locus_tag="AORI_RS83840"
     CDS             30733..30900
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154180.1"
                     /locus_tag="AORI_RS83840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6222 family protein"
                     /protein_id="WP_167337763.1"
                     /transl_table=11
                     /translation="MTTNESATPAPAPTAERPPVVTTMPRLGRGVCWRDIVREIELDEL
                     EREARMREAA"
     gene            30897..32600
                     /locus_tag="AORI_RS50225"
                     /old_locus_tag="AORI_1843"
     CDS             30897..32600
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154179.1"
                     /locus_tag="AORI_RS50225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1843"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_016332233.1"
                     /transl_table=11
                     /translation="MTLQGDPGAQRTEDSEVVPLPEDRLRRSRIPRPTDGRVIPLARGA
                     EPVHPPEPTMPLLRTQRDELREHIVDGRLDGVRRQHSLGKHTARERLDLLLDPDSFTEV
                     ELYRRHQASGLGLAENRPYTDGVIAGSGTIDGRRVFVYAQDFTVFGGSLGEAHAAKIQK
                     VMDLAIATGSPLIGLNDSGGARIQEGVMALNGYGGIFRRQVEASGVIPQISVVLGPCAG
                     GAAYSPALADFVFMVRDTARMYLTGPDVVETVTGERVSHDELGGADVHGASSGVATVVH
                     DDEETCLADVRYLVSLLPSNYLDPAPREPSQDAGKDRRPRFAELVPVEPNKPYDMRDVF
                     SELADDGEFFELHERWAQNVLCALARIDGRVVGLVGNQPVVFAGVLDGPASQKAARFVR
                     FCDAFSIPLVTLVDVPGFLPGVEQEHSGIIRHGAQLLHAYCEATVPRVQVILRKAYGGA
                     YIVMDSRSIGTDLSLAWPTNQIAVMGAEGAVNVLFRKDLAVAPDPDALRAHLVAEYTEE
                     FMNPQYSAERGLVDDIIDPADTRSAVARALDMLQDKRKAAPQRKHGNHPI"
     gene            32612..32803
                     /locus_tag="AORI_RS50230"
                     /old_locus_tag="AORI_1844"
     CDS             32612..32803
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154178.1"
                     /locus_tag="AORI_RS50230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1844"
                     /product="acyl-CoA carboxylase subunit epsilon"
                     /protein_id="WP_016332234.1"
                     /transl_table=11
                     /translation="MSPSGMDSAPVFRVLRGDPEDADLAALVAVFTALASAAPPPAAPA
                     RSAWSPLVAPTWRTSALR"
     gene            complement(32931..33107)
                     /locus_tag="AORI_RS83845"
                     /old_locus_tag="AORI_1845"
     CDS             complement(32931..33107)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154177.1"
                     /locus_tag="AORI_RS83845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1845"
                     /product="hypothetical protein"
                     /protein_id="WP_016332235.1"
                     /transl_table=11
                     /translation="MSAAERQRTCAACGGAFEPGERTELETVVDGGILYVAVHTRHSTY
                     PPRRETEAARRLA"
     gene            33398..33547
                     /locus_tag="AORI_RS83850"
     CDS             33398..33547
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154173.1"
                     /locus_tag="AORI_RS83850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167337764.1"
                     /transl_table=11
                     /translation="MTAQVRIWVVTDDLDPRGAVEADVTAFVPEPRQAAENDFPAEHIV
                     LGYN"
     gene            33651..33959
                     /locus_tag="AORI_RS50235"
                     /old_locus_tag="AORI_1846"
     CDS             33651..33959
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154172.1"
                     /locus_tag="AORI_RS50235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1846"
                     /product="DUF6235 family protein"
                     /protein_id="WP_016332236.1"
                     /transl_table=11
                     /translation="MAMRLQLTSGLQVLEEWAINAPQADRNVIYEALFAVADGSAFLIY
                     DIFGDGRDPHQFIILVKHDLVIRIGLKRTDSSFEIVYIGALEHGTPAAAWADDVDGS"
     misc_feature    33688..33704
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    34018..34032
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.89"
                     /tool="antismash"
     gene            34200..34685
                     /locus_tag="AORI_RS50240"
                     /old_locus_tag="AORI_1847"
     CDS             34200..34685
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670857.1"
                     /locus_tag="AORI_RS50240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1847"
                     /product="DUF6423 family protein"
                     /protein_id="WP_016332237.1"
                     /transl_table=11
                     /translation="MAGVADVRRRVLMISGAIDTTEHDISVSVNLPEPGRWQVIKSETN
                     LTDKTWVAMQVVTDEDSTFVNDADTLVLSRQFSKSFMTPDQRRLTFYDGEVRPGEAVLK
                     VYSLDAGGRKPTYSYSRYSPIATDTAEQSQQTLDELISNGMKQRPVIELIVPVTVIG"
     gene            34694..36013
                     /locus_tag="AORI_RS50245"
                     /old_locus_tag="AORI_1848"
     CDS             34694..36013
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034656.1"
                     /locus_tag="AORI_RS50245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1848"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_016332238.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.7e-14, bitscore:
                     51.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITFVPEPHLLESPRGREWPVLPGSRAAMTPEPPSAADVVIVGAG
                     PAGLAVASALWHHGVRDLVLIDRDGRPCGRFFDRVDLLGQRVLRSPYEHHPGVEGYRDC
                     ELLDFARLHWSVLTPVERREIRMAQAGHRSVVPVDVFEAYCRHLAASHHVTERTWRGSV
                     REVLPTSDAVTVRADRFSVTARHVVLCLGEERRSAPDTWWGGGHPPRGVTYWDEPVPGG
                     GKRLAVVGAGLTAAHLISNGLAQGREVHWVVREAGERYQCADVNSSFFRPEGRARFDGV
                     SWAERLELMGRFRRASIMFEFRPMLEAAEAEGRLIVHRGKAITKVTPGVGLHLEDGSRV
                     SADHAVLALGTTPSIGDGLMPDEAVLDRGGWPRLDERTFAYTGAPRVFAVGAAAGMALG
                     PAARNIDGHRVATARVAAAVAENLRRDTPLRTATKDVARV"
     gene            36006..36482
                     /locus_tag="AORI_RS50250"
                     /old_locus_tag="AORI_1849"
     CDS             36006..36482
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629596.1"
                     /locus_tag="AORI_RS50250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1849"
                     /product="DUF6187 family protein"
                     /protein_id="WP_016332239.1"
                     /transl_table=11
                     /translation="MSEPYDSRFTLPSIDDAPSTESGVILLGLDAERLLAGVGLARLAD
                     EPALVALAVDQARHEALDLGLGALVEAGIVRWRAVRPLIEAGPEMTAAGSLRREWEHAT
                     ARVTATVTGLGPASVACLAACWLRRDDVDEFAAHGRAPEKGSGTQDVLSRVFAD"
     gene            36472..37008
                     /locus_tag="AORI_RS50255"
                     /old_locus_tag="AORI_1850"
     CDS             36472..37008
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629595.1"
                     /locus_tag="AORI_RS50255"
                     /note="This protein belongs to a clade of uncharacterized
                     proteins related to peroxidases such as the
                     alkylhydroperoxidase AhpD; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="AORI_1850"
                     /product="peroxidase-related enzyme"
                     /protein_id="WP_228688326.1"
                     /transl_table=11
                     /translation="MPTDATLLQVFQKFPAPASKLLELHELLMRAPSAFGAGERELIAA
                     YVSGVNDCRYCHGVHTVTAEAFGVPEGLLAAALADLDSSPVDDRMKPVLAYVGKLTRTP
                     ARMTDADAEAVYAAGWDETALHDAVLVCALFNFMNRMVEGLGIRADAAYAKISGVRLKE
                     GGYAGLATLLDEASR"
     gene            37278..37469
                     /locus_tag="AORI_RS50260"
                     /old_locus_tag="AORI_1851"
     CDS             37278..37469
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332241.1"
                     /locus_tag="AORI_RS50260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1851"
                     /product="hypothetical protein"
                     /protein_id="WP_016332241.1"
                     /transl_table=11
                     /translation="MMNTATDNVRSLFAVRGIDTGFAGNEVELVIDRFDHWTNQHRSEA
                     FSCFTGACCTAPPLAEAS"
     gene            37712..38320
                     /locus_tag="AORI_RS50265"
                     /old_locus_tag="AORI_1852"
     CDS             37712..38320
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154162.1"
                     /locus_tag="AORI_RS50265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1852"
                     /product="response regulator transcription factor"
                     /protein_id="WP_016332242.1"
                     /transl_table=11
                     /translation="MVIRVLVAEDMHIVRGALVALLRLEPDIEVVSEVASGDEILPAAR
                     DSRTQVAIIDIDLPGKDGLTAATELHEQLPEVRTLILTSLGRPGTLRRALAAKVSGFLL
                     KDAPAEKLANAVRGVAAGRRMVDGDLALAAWDTVECPLTPREIDVLRLTAEGRDTLEVA
                     AKAFLSTGTVRNYLTTIVSKLNARNRVDAIRIAKESGWI"
     gene            complement(38317..40620)
                     /locus_tag="AORI_RS50270"
                     /old_locus_tag="AORI_1853"
     CDS             complement(38317..40620)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034661.1"
                     /locus_tag="AORI_RS50270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1853"
                     /product="histidine kinase"
                     /protein_id="WP_228688327.1"
                     /transl_table=11
                     /translation="MTAEPLGTAGVDRRPRRALFLAGLIITVVFVNSCLFGLLAVLFRP
                     GVDFWQGLLAVLYVGPVLAIQLLYFSRPAVRLDTRLAKAMLAVQACLAFLPTLHFDAAL
                     SSLTTLAAGSALLLFRPRTGWTVFTVFMAGTIWILWTYDETWLGAVFDSVTAVLYALVV
                     YLLTWLARLVTELHQARTELARRAVAEQRLAFARDLHDLLGLSLSAIALKGELVHRLLR
                     KSLDRAREELAEITGIAQRTLSDVRSVARGYRELSLDKESRTAVSLLSASNVAVRVDLE
                     QVDLPVKLRTLLAKVLREGVTNVLRYTGVEHCEITVRESGGRVALEIVHDGTAHDDVPE
                     ETAESLREVTGEVAGHGGKLSAGPDAAGRWRLHAELPVPEQAEPTETALAEGSGHWSRI
                     DARNVQWTMTVVFIVFSLSAMARAFMLTDDGWSLALIAGYLTALTTLQLSYFARPNVRL
                     RSRQSYALLFVQACLIFLPLIPLGSAWVSLPSLFAGTALLVLPPLAGWTAFAVTAAGVV
                     LIRIAYGTDFLGGFYTFASILNTGLMVFGLIWLIRLVTELGETRKRLAEVAVAEERLRF
                     ARDLHDLLGMSLSAIALKSELTTRIMDIDTDRASAELLEILGLTRQALTDVRSVASGYR
                     ELSLDQESRSAQAVLVAADVQVRLEIEHEDLPTTVRTVLAVVLREGVTNVLRHSKVERC
                     EIAVRRTGDGVALDIVNDGVVNGRPPKPEQPVRVEAPGSGITNMSDRVAGLGGELTAGV
                     EPDGRFRLRAVVPV"
     gene            40965..41585
                     /locus_tag="AORI_RS50275"
                     /old_locus_tag="AORI_1854"
     CDS             40965..41585
                     /EC_number="2.7.7.87"
                     /GO_function="GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154159.1"
                     /locus_tag="AORI_RS50275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1854"
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="WP_005154159.1"
                     /transl_table=11
                     /translation="MARYFDVHPENPQRRAIGQVVDILREDGLIAYPTDSCFALGCQLG
                     NKQGIDRIRSIRKLDDRHHFTLVCQDFAQLGQFVHVDNAVFRAVKASTPGSYTFILPAT
                     KEVPRRLLHAKKKTVGVRIPDHVVTQALLGELGEPLLSSTLLLPDQEEPMTQGWDIKEH
                     LEHVVDAVIDSGDCGVEPTTVIDFSSGEPEIVRRGAGDTSRFE"
     gene            complement(41624..42310)
                     /locus_tag="AORI_RS50280"
                     /old_locus_tag="AORI_1855"
     CDS             complement(41624..42310)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034662.1"
                     /locus_tag="AORI_RS50280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1855"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_016332244.1"
                     /transl_table=11
                     /translation="MTARTYGQFCGLARALEIIGERWSLLVIRDLVLGPKRFDELQHGL
                     PKIPTSILSTRLNELERHGVVQRRVLSQLDAGVVYELTEYGNDLDQILLQLGLWGARSL
                     TDPAADDLFTLDAAILSLYTTFQPDAARGIDCAFELHYGDQMIVHAVVEDGAMTAGEGP
                     HPNPDLVIEPRGPVVLKLLNGEMDAASALTCGAVAIKGEPAMLELFTRLFHIPSAPSKA
                     EGLVTH"
     gene            complement(42356..43135)
                     /locus_tag="AORI_RS50285"
                     /old_locus_tag="AORI_1856"
     CDS             complement(42356..43135)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034663.1"
                     /locus_tag="AORI_RS50285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1856"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_016332245.1"
                     /transl_table=11
                     /translation="MHAMTIEAGDTARLLGPLELHIGGADRAPSTPKLLQLLAMLLIRP
                     GKTVHVDSLVHELWNDAPPRSVRRTLHTYVHHLRRHLDPGGNGGLLVTSSPGYRLEIDA
                     GVVDVSEFQRLHRLGSDLLDEGDNAAAAHAFRTALDLWSGPPLANIHCGPTLAAYTVYL
                     LEHRRNARDLWIEAEIRSGRHREMLGVLRSLTTADPFDETLHAHLIRALGLSGRRSDAL
                     ASYEWLRSRLEDELGVTPCAELRELHRELLSEGHPVR"
     gene            complement(43302..43907)
                     /locus_tag="AORI_RS50290"
                     /old_locus_tag="AORI_1857"
     CDS             complement(43302..43907)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003099099.1"
                     /locus_tag="AORI_RS50290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1857"
                     /product="response regulator transcription factor"
                     /protein_id="WP_043847969.1"
                     /transl_table=11
                     /translation="MIRVLLAEDMHMVRGALVALLNLEQDIEVVAEVSSGDKILPMAAE
                     YLPDVAIIDIDLPAKDGLAAASELCQQLPSVRTLILTSLGRPGTVRRALDAKVNGFLLK
                     DAPADKLANAVRSVAIGRRVIDSELALSAWETEDCPLTPREAEILRLAANGRTVADIAA
                     ELFLSPGTVRNYLATVVTKLNARNRVDAIRIATDSDWL"
     misc_feature    44113..44129
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.45"
                     /tool="antismash"
     gene            44330..45325
                     /locus_tag="AORI_RS50295"
                     /old_locus_tag="AORI_1858"
     CDS             44330..45325
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034665.1"
                     /locus_tag="AORI_RS50295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1858"
                     /product="DUF1702 family protein"
                     /protein_id="WP_043848644.1"
                     /transl_table=11
                     /translation="MSSLLGALRKVMFAPSLASVGFEGRGFGVPRTPSTARLESIPQSV
                     VCGFEWGIDAPALWEAERRLDMVEPEMRGFAYEGAAMAFTILDVMPGGRKDRTAELMSG
                     PGLPHVFLTYIGIGFAMARLPRPLWKKVLPELDGVPFHPTMSWLAVDGYAFDRAYFDTR
                     KWVDEQFVPKQYPWAGAPAYFPRACDQGIGRALWFINGGDPVKVAAAVDRFPAGRRPDL
                     WSGVGLASTFAGGCDRPGLVRLREAAGEHQDELGLGVVFAVKARTFSSFVPPHTRRAAR
                     ALAGLSVEEAVELADSTEVTEDAADGTPAYELWRQNIREGLAPSAGRLSA"
     gene            complement(45404..46102)
                     /locus_tag="AORI_RS50300"
                     /old_locus_tag="AORI_1859"
     CDS             complement(45404..46102)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034666.1"
                     /locus_tag="AORI_RS50300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1859"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_016332248.1"
                     /transl_table=11
                     /translation="MNEKLGEELTIDDIARAATFSKFHFTRVFQQATGVSPGRFLSALR
                     LDEAKRLLLTTSITVADISHRVGYNSVGTFSTRFSSRVGLSPSAYRRQGGFQRRLAGEP
                     RPGPKRAIVRGFVSAPPEISPGLVFVGLFPTRIPEGAPVRYTVIDAPGPYQLTEVPEGD
                     WHLVAHCVTGPLTRRGTGYTGHHGPITVEPGVTARLADLRMRPKRLFDPPVLLALPDLR
                     HRPEPFQRAA"
     misc_feature    complement(46269..46281)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            46560..47165
                     /locus_tag="AORI_RS50305"
                     /old_locus_tag="AORI_1861"
     CDS             46560..47165
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154150.1"
                     /locus_tag="AORI_RS50305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1861"
                     /product="response regulator transcription factor"
                     /protein_id="WP_043848645.1"
                     /transl_table=11
                     /translation="MIKVLVAEDMHIVRGALVALLGLEPDIEVVAECASGDEILPLAQS
                     ARPDIALIDIDLPGKDGLTAAAELHEQLPGVRTLILTSLGSPGTLRRALAAKVNGFLRK
                     DAPADRLANAVRGVAAGRRVVDGDLALAAWDSEECPLTAREIEVLRLASVGSDPTEIAA
                     ELFLSAGTVRNYLTTIVSKLSARNRVDAVRIARESGWL"
     misc_feature    46588..46604
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.74"
                     /tool="antismash"
     gene            complement(47177..48259)
                     /locus_tag="AORI_RS50310"
                     /old_locus_tag="AORI_1862"
     CDS             complement(47177..48259)
                     /EC_number="6.3.2.2"
                     /GO_function="GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042398 - cellular modified amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1165: carboxylate-amine ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629584.1"
                     /locus_tag="AORI_RS50310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1862"
                     /product="glutamate--cysteine ligase"
                     /protein_id="WP_228688328.1"
                     /transl_table=11
                     /translation="MTYTVGVEEEFVLLDPVDGSVALRAPELLESLAPGTDVTGELMRF
                     QIETATGVCRGLDEVRSELTRLRQMVATAAEADGCLMVAAGIPPAGLRGDTLTPEPRYR
                     RMAQAFPDLIGEAGTCACHVHVGLPSRDLGARVLAGLRPWLAPLLALSVNSPVENAADS
                     GWASRRFPIWNRWPTAKPPEEWSGAAAYDRSIREALRRGAALDAAGVYFYARLSPRHPT
                     VEVRIADVCLAVDDAVLLAALVRGLVATCAATTRPPRARGARIDAALAAAARRGLDGPG
                     VDVFTGREADQRELLGELVEFIRPALTAAGDAEDVDRGLDSLFEHGTGAARQRRLLAEA
                     ASPGEFAADLAHATMNVPAR"
     misc_feature    complement(47375..47377)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            48408..49346
                     /gene="pip"
                     /locus_tag="AORI_RS50315"
                     /old_locus_tag="AORI_1863"
     CDS             48408..49346
                     /EC_number="3.4.11.5"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030163 - protein catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (37-295). E-value:
                     1.5e-30. Score: 98.6. Matches aSDomain:
                     nrpspksdomains_AORI_RS50315_Abhydrolase_1.1"
                     /codon_start=1
                     /gene="pip"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034669.1"
                     /locus_tag="AORI_RS50315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1863"
                     /product="prolyl aminopeptidase"
                     /protein_id="WP_016332252.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.1e-08, bitscore:
                     33.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 4.1e-28, bitscore: 97.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDLYPPAEPYDKGLLDVGDGNLVYWETCGNPAGKPAVMLHGGPG
                     QGCTPGMRRMFDPARYRAVLFDQRGCGRSTPHASDPATDMRHNKTDHLVADMERLREHL
                     GIERWLVTGGSWGTTLALAYAERFPERVTEIVVSAISTTRPSEIDWLYHGAGRFFPEEW
                     DRFRGDLSGDLVAAYARLLEDPDPRVRIEAARSWCRWEDTVLLLEPDATVHNGPIGEWE
                     LALARIVTHYYSHAGWLEPGALIRDAGLLRDIPGVLIHGRRDLSCPVDTAWELARAWPG
                     AELLIDDDSGHHSSDVKRAWKLAALDRFASS"
     aSDomain        48519..49292
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AORI_RS50315_Abhydrolase_1.1"
                     /evalue="1.50E-30"
                     /label="AORI_RS50315_Abhydrolase_1.1"
                     /locus_tag="AORI_RS50315"
                     /protein_end="295"
                     /protein_start="37"
                     /score="98.6"
                     /tool="antismash"
                     /translation="VMLHGGPGQGCTPGMRRMFDPARYRAVLFDQRGCGRSTPHASDPA
                     TDMRHNKTDHLVADMERLREHLGIERWLVTGGSWGTTLALAYAERFPERVTEIVVSAIS
                     TTRPSEIDWLYHGAGRFFPEEWDRFRGDLSGDLVAAYARLLEDPDPRVRIEAARSWCRW
                     EDTVLLLEPDATVHNGPIGEWELALARIVTHYYSHAGWLEPGALIRDAGLLRDIPGVLI
                     HGRRDLSCPVDTAWELARAWPGAELLIDDDSGHHSS"
     misc_feature    49023..49025
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 gaagctaagc ctgacagcgc cgatggtact gcaaccgaag ggttgtggga gagtaggaca
       61 ccgccggact aacattgaag aaaagggtct gggacctggt cgagaaccga gagttctccc
      121 aggtcccaga ccttttttca tacccggaac ccgccacacg cgtgattaaa gacgcgacac
      181 gcgtgattga aggcggaaca cgcgtgatca gacggacgac acgatgcccc ggtcgtgtcg
      241 tcccgcccaa cacgcgtgtc gtccacctga tcacacgtgt cgcccgtcca atcacgcgag
      301 tgacgccttc aatcacgcga gttgcggcct ggagcacgcg agtgacgggg tcgggcacgt
      361 gggggagggg cgggggcccg agcatttaga ggactaaatg cgggaggggg cggggcggcg
      421 gaggtggtag atgtccatga tccagccctt tcgggagcgg gcggaggcgc ggacggagcg
      481 gatctcctcg gcgaggtccg cggtcagcgg gccggagagc aggagctcgt cgggggtgcc
      541 gaggtacgcg ccccagtaga tctccaggcc cgtgtccacg aagcgggaga acgtgcaccc
      601 agcgtccagc atgacgaaga cgtcgtcgac gtccgcgggc cagccggcct cgaggcggcg
      661 gccggtggtg acgagcaccg ggcggccgat ctggttcatc gtggtccggt gccgggacgt
      721 cagcgcggcc acgctgctga ccccggggat gacgtcgtac tcgaactcga cgttgccccg
      781 gtcgagcacc gcgtccagca gggtcagggt cgagtcgtag agcgccgggt caccccagac
      841 gaggaacgcg ccccgctcgt cgggccccag ggaagcgatc atgttctcgt agacgtcggt
      901 gcggagccgg tgccagtcgg cgacggcctt ccggtagtcg tcaggagtac ggtcgcgttc
      961 ggggtccggt gcccgcacga cgcggtagcc gggctgctcg acgaagcggt cgaggatctc
     1021 ctggcgcaga gccaccaggt cctgcttttc cgagcccttg tcgagcacga agaacacatc
     1081 ggtctcgttg agccgccgga tcgcctggac ggtcaggtgg tccgggtcgc cggcgccgat
     1141 gccgatggcg gagatcttcc tcatttccgc agtgtccccg caccctctgt gcacacccct
     1201 acccccacgg ggtataaagg aagtgatcgc tccacctgtc ctgtagagga gttcgaaccg
     1261 atggccgaaa ccacctacac cgtcaagggc atgtcctgcg ggcactgcgc ctcctccgtc
     1321 accgaagagg tcagcggcat cgcgggcgtc agcgccgtga acgtggacgt cgccagcggc
     1381 aaggtcaccg tcaccagcga ggcgccgctg gacgtccaag ccgtcgacgc ggccgtcacc
     1441 gaggccggtt accagctcgt ctcgtgagca ccgccgtcaa ggtgtcggcg ttcgccgcgg
     1501 ctctggtcgc ggtgttcgcc gtcgcctggg cgatcggctc cgccgtcggg ccactggacg
     1561 aggagccgcc cccgccggcg ccggccagtg agcaccacgg gcaccacccg ggaggtacgc
     1621 cgtgacgtcc cagcgcgtcg aactggccat cggcggaatg acctgcgcgt cctgcgccgc
     1681 gcgggtcgaa cgcaaactga acaaggtcga tggcgtctcc gccacggtca attacgccac
     1741 cgagaaggcg caggtcgact tccccaccgc ggtctcggtg gaagacctcg tcggcgtcgt
     1801 cgagtccgcc ggctacacgg cccagccgcc caagcccgac gaagacgcgg agcagaccgg
     1861 ctccctgaga acccgcctcg tggtttccgc cgtgctcgcc gtgccggtga tcgtgctggc
     1921 gatggtcccg gcctggcagt tcacctactg gcagtgggtc tcgctggcct tggccgcgcc
     1981 cgtcgtcacc tggggcgcgt ggccgttcca ccgccccgcc tggacgaacc tccgccatgg
     2041 cgccgccacc atggacaccc tgatctcgct cggcgtcgtc gccgccacgc tctggtcgct
     2101 gtacgcgctg ctgttcggca ccgccgggac acccggcatg cgccacggct tcgagctgac
     2161 catggaacgc gggcacggcg cgggcaacgt ctacctcgag gtcgccgccg gggtgaccac
     2221 gttcctcctc gcgggccgct acttcgaggc ccggtccaag cgccgctccg gcgccgcgct
     2281 gcgggccctg ctcgaactcg gcgcgaagga cgtcgcgctc ctcaaggacg gcatcgagag
     2341 ccgtgtcccg atcggcgagc tgaggacggg cgacgagttc gtcgtgcggc cgggagagaa
     2401 ggtcgccacc gacggggtgg tgaccgacgg tggctcggcc gtcgacctga gcatgctgac
     2461 gggtgaagcc gtcccggtcg aggtggtggc cggggacgcc gtcgtcggcg gaacggtcaa
     2521 cgcgagcggc aggctcgtcg tccgcgccac ccggatcggc gccgacacgc agctcgcgca
     2581 gatggcgcgg ctggtcgagg acgcgcagaa cggcaaggcg cgggtccagc gcctcgccga
     2641 ccgggtgtcg gccgtgttcg tcccggtggt gatcgccctc gcggtcggca cgctcggctt
     2701 ttggctcggc gcgggcagcg gggccgacgc cgccttcacc gccgccgtcg cggtcctgat
     2761 catcgcctgc ccctgcgcgc tcgggctggc cacgccgacg gcgctgctgg tcggcaccgg
     2821 ccgcggcgcg cagctgggca tcctcatcaa gggcccggag gtgctcgagt ccactcgcgc
     2881 ggtcgacacc gtcgtgctgg acaagaccgg cacggtgacc gcggggaaga tgagtctcac
     2941 ggacctgttc ggcgaggacg agaccgaggt cctgcgcctg gccgcggcgg tcgagcacca
     3001 ttccgagcat ccgatcgccc gcgccatcgt cgcggccgcc gaggagaggc tgggcgagct
     3061 gccgcaggcc ggtgggttcc gcaacgtcga gggcctgggt gtcgtcggcg aggtcgaggg
     3121 caagaccgtc ctggccggcc ggtccgccct cctcgaccag cacggcatcg ccgtcggcga
     3181 cgagttcgcc caggtcaaga aggtcgccga ggaacgcggc gcgaccgccg tcgtcgtcgc
     3241 ctgggacggc gagacacgcg gggtggtggt cgtcgccgac acggtcaagc cgacttcggc
     3301 cgaggccgtg gccgggttga aggcgctcgg gctccggccg gtcctgctga ccggcgacaa
     3361 cgccggttcc gcggcggccg tcgccgccga agtggggatc gacgaggtca tcgcggaggt
     3421 gctgccggcc ggcaaggtcg acgtcgtcaa gcggctgcaa gccgaaggcc gggtggtcgc
     3481 catggtcggc gacggcgtca acgacgcggc cgcgctcgcg caggccgacc tcggtctctc
     3541 gatggggacc gggaccgacg ccgcgatcga agcgggcgac ctcaccctgg tgcgcggcga
     3601 cctgcgcgcg gccgtggacg ccatccggct cgcccgccgc acgctcggca cgatcaaggg
     3661 caacctgttc tgggcgttcg cctacaacgt cgccgcgctg ccactggccg cgctcggcct
     3721 gctcaacccc atgatcgccg gggccgcgat ggcgttctcc tcggtgttcg tcgtcaccaa
     3781 cagcctgcgg ttgcgacggt tcaggaccgg accagccggg cgatggcgtc ggacgcctcc
     3841 cggaccttga ggtcggcctc ttcaccgccc gcggccgcgg cgtggaccac acaggtggcg
     3901 aggtgctcgt ccagcagttc gagggagaac gactgcagcg ccttcgtggc cgcggacacc
     3961 tgggtcagga tgtcgatgca gtacttgtcc tcttccacca tccgctgcaa accgcggatc
     4021 tgcccctcga tccggcgcag gcgcttgagg taggcctccc gctcggtgcc gtagcccgtc
     4081 attcccgcac ccgttctctc gtcgttccct gtcgtggtcc cactataccc accccacgta
     4141 tgtgccggac ggagccgaat tcgcgggtgc caggatgtcg agaacgatcc ggccgctccg
     4201 actcctgcgt gagtggccgg gcaccggccg cgcgaccagg aggaacaccg atgaagtaca
     4261 tgatcatgat cacgatgaac cccaccgcct gggacgccct ccccgaagag gagcgcgacg
     4321 aggtggtcgc ccgcatcgac cccttcatga agaagctcac cgagagcggc gaactgctcg
     4381 ggacgcaggc gctggcggag ccgaaggaaa gcacggtggt ccgggtgcgt gacggcgtcc
     4441 cggtggtcac cgacggcccg ttcgcggagt cgaaggagta cctggccggc ttctacctgg
     4501 tcgaatgcga cagcaaggag cgggcgatcg agatcgcggg ccagatcccg gacgcgcatg
     4561 tcaacgcgat ggagatccgg ccggtggtct tctcgtccgg cgacaacgct tagtcaggtg
     4621 gcggcggctt cggtgccggt gcgggcttcg ggcctgctcc ggcgctgaac gggcacttcc
     4681 ggtttcggtg agtccggtac ggccagcacc acgccggctt cggtgagcag ttcgcggcag
     4741 ccggccagct gtttcagcac gtcgtcgcgc aggcggaggg ccacatcggc cttctgccgc
     4801 gcttcggcga ccaggcgctc ggcctcttcg gcggcgtcgt cgagcagttt ccgcgccttc
     4861 gcctgcgcgg cttcgtcccg cgcggcgagc gcgcgcatcg cctccgcgcg gcgcagcgtc
     4921 atggcgcgct cgaagtcttc ggcgacccgc ttccgttctt cttcggcctt cgcggcttct
     4981 tcggcggctc gcgcggcgat gtcgtcggct tcctcgcggg tgagttcgag catccggcgc
     5041 gagcgctcct gcaacgcgtc cggtgcgatc ggcacgcggc tgatccggtc gacgctggcc
     5101 ttcagttcgc gattttcctc ttgtgtggcg gcgagctcgc cggcgagaac ttgcccacgg
     5161 cggatcgcct cgtcgcgttc ggcttccact cgtcgtagtt cggcttccac ctcgcggacg
     5221 aattcccgga cctgcgcgcg attgaaaccg cgccacgcca gatcgaagcc gggcatctcc
     5281 attggtcacc tccacagtgg tcgatgtgtc gccgttgggc gcttttcttt gccacacggg
     5341 gctttcaacg accagtgtgc ctgaaggcgc gacgacacgc gccacgggtg ggtggtcttt
     5401 gcggtgaacg gtccgccgca agcgggaaga agggtgaagc tccccggcga tgggagaatg
     5461 gacgaccatc gcatacccca cgggaggtgg ccgcgtgacg agcagccgaa ttcgggtccc
     5521 tggctggaat acggcgacag cggccgaagg atatcggcag gtcagggaga acatcgcgat
     5581 cttggtcacc gatcacgcgg gggcggggga gcgggccgtc cccgcctgtc cacagtggac
     5641 cgtgcgcgat ctgatcgcgc atctgaccga gatctgcgat cgggtgatca cccggttcgg
     5701 cggtgaggcc tgcccgattc cggagtcggc ctcggccgtc gaattgctga aactctggct
     5761 cgaacgcggt cccgaggccg acaccctcct cgccgccgac ggcgacggga agagccgtgg
     5821 cgacatcatg gtgatggacg ccttcaccca cgagctcgac atccggtacg cgctcggcgc
     5881 tccgccgccc gaagcgcacg cggcctggct tcggggattc gaagtgctcg tcagcgggct
     5941 cggcgcctcg ctgggcaggc acgggctgcc ggggctgcgg atcgagaccg agggcgcgac
     6001 ctggatcgcc ggcaccgaac cggtcgccgc ggtgctctcg ggcgcgcccg cggacctgta
     6061 ccggacgctc gccgggcgcc ggagcccggc ccagatcacc gccatggact ggctgggcga
     6121 tcccgggccg tggctccggg ccttcacctg gggaccgttc accccgccgg aagcggagat
     6181 cgaacggtga tcagccggcc ggggacatcg aggacagcgc cgcggccagc gcgagcacca
     6241 cggccacgat cagcacctcg accccgacgc tgacccgcag tttccgcagg tcggcggtca
     6301 ccactccggt gccgccgcgc ccggagatcc cgcgccggac ggcggtgcgg ctcaggttcg
     6361 ccaccagcag caacgcggcg aacccggtga gcttcagcac gaagacgatg ccgtacgccg
     6421 acgtccagag cgcctccacc gaggggacga gccggaagcc caggtaggca ccgctgacca
     6481 ccatgatcac gatcgaccgg gtggcgatcg ggtggaaccg cgccagcgcg ggctcggcct
     6541 ccgacgccga ataccggccg cgcaggagca cggccagctg gatcagcccg cccacccaga
     6601 cggccatcgc gccgaaatgc gcgaggtccg cgctgaccga gaggaacatg atcttgtcgg
     6661 ccaccgcgtg cccggtcgcg gagaaactca gcatcacgat gaacccggcc gcgatgccga
     6721 ggttctcgta gcgcgaccgc agccggtccg gcaggtcgcc ggccagcagc cgccgcacga
     6781 tcacggcgag cgcgacgatc gctgccaggc gcaggagcag gagtttcccg tacgccaccc
     6841 gcagggtcgc ctcgatcagc gcgccgtcga agaccgcgcc caccccgcgc cccgcgacgt
     6901 acgggccttg cagcaggaac ccggccacgg ccgtcacacc ggagagccac aggccggcgg
     6961 tgatcagctt ccgtgccgcc gggtccgccc ggccgcccgg acggcagacc accaggaaca
     7021 ccagcccgcc gagcagcgcg accccgccga aggatcccca gcggaacgtg gtgaacagcg
     7081 cgtcggtcac cgggtcggtc ccggtggagg cggacaccgc gcccgccgac gtgatcaggg
     7141 ggccggtgcc gatcacgaac gcgatcgtgc cgcgtaccgg atgcgagtcg gtcgagacga
     7201 aggcgtactc gacgagatag ctgccgtcgg gaaggtccgg ttcgagcgcg acggcgacct
     7261 cttcggcgac ttcaccgggt tggaacaccg ggccggacac cacgtcggtg ccctgttgat
     7321 cgacgacctt gatcgagttc ggctggatgc cgatgttctc cgacagggtg atcgagaccc
     7381 gcgccggcgc cgaggtgagc cgggcgccgt cggcggggtt cgaggagagg agctcgacgt
     7441 gggccgaggc cggggccgcg gtgaggaccg cgaccccgaa ccacgccgcc acgagggcca
     7501 ggagtgcgca gagtctcccg gtcacgacgc cgcggtcgcc agctcacgcc ggctgacggg
     7561 cgagcacgtg cagccggtca gctcccgctc ggcggcggag gccttccggt gcacgagcat
     7621 cgcgatgatc atcgggatgg tgacgatcgt gttgtagaac aggtgcagtt ccacgcgcgg
     7681 gatgaacagc tggatgatgc tgctcggcgc ggtgccgccg ccgagccgcc agccggtctg
     7741 cgcctggatc agcaggagca gatgctcgat gtggtgccag aactgcaggc cgagcgccag
     7801 gttccaccac tgccgcgagc ggccggcgaa acccttgcgc agggcgaaca ggaagatcag
     7861 catgacgatg gcgtagccgt agtgcagcca ttcggagctg atcagcttgg ggaacgggat
     7921 cccgagcaca ccgcgggcgt ccggggtctt ccagccgagc gcgtagatct ggaaggcctg
     7981 cacgaggtgc tccgcccagt gggccacgac gaccaccgcg aaggtgagga gcgccgcgcg
     8041 gtggtacttc ccgttgagcg aggcgagcag acccggacga ggcgaatcga gtgcggccat
     8101 gaaagggctc ctagggcgaa agaccgaccg gtgacggatg tcgacgatat cccgcgttcc
     8161 gaggatttcc gttactccgg attgctgatc cgaccagcgg tgttacgccg gatggatcag
     8221 cggacgacga ttccgtcgga cattttcgga gcggcgggaa tgtggaacaa ttccgtgaac
     8281 agctccagat attcgaagtc gccctcgatg cggatcttcc cggtccgcgt cgcgtcggcg
     8341 gcggcgagat ccccgctcag caggtccttg atgaacgggc ccagcggttc gatgaccgcg
     8401 tcggcgccgg ggtgcgcgcc ctccgcgacc ttgagcgcgc cgtcctcgac gatcgcgtgc
     8461 aggaccatct cgcccgggta gcgcagctcg taggtcacct ggacgccctt ggccttttca
     8521 ctccggaagg tcgtgtacag cgaaaggatc gccgaatcca gggtgaagac gtcctcggcg
     8581 gcgggctgcc cgagcgatcg cgccccccag agcccgaggt ccagcacgat ctggtcgagt
     8641 tcgctgccgt attcggtgag ttcgtagacc accgcggcgt cgagctgggg gagcaggcgg
     8701 cggcggagca caccggactg ctcgagttcg ttgagccgcg cggacagcgt gctcgccggg
     8761 atcttcggca gacccgcctg cagttcggtg aaccgcttcg ggccgaggac gaggtcgcgg
     8821 acgatcagca gcgaccagcg ttcgccgatg atctccagcg cgcgggccag cccgcagaac
     8881 tgtccatagg tacgactgct catccgtcga tcctcacttt cgtttccgtg gcggggttca
     8941 cgcgggttca ccttcggaaa gcaggtcgtg gtgcaggacc tgcagttcgt cacagggttc
     9001 cacgcccagt tcgttgttga gtctcgcccg cacctgacgg tacgtggcga gcgcgtcgga
     9061 gcggcgcccg ctgcggccga gcacgcggat cagctgcccg tgcagggcct cgtcgagcgg
     9121 gttcgcggtg accagggaac gcagttcgcc gatcagctcg tgccgcatcc cggccgcgat
     9181 gtccgcctcg atccgcaggt gcagcgtgct gcgccgctgc tcgacgaggt cgaccgcgta
     9241 cgccgacagc accggtccac agtggacgtt cgcgagcggc gggccggacc acaggtcgag
     9301 cgcggaccgg aaggccttcg ccgcttcggt gtgctcgccg cgcaggtgca gctcccggcc
     9361 cttgtgctgc aactcctgga actcgaagac gtccacctgc tccggcgcga tgcggaacac
     9421 gtaccccggc ggtttcgtcg ccagcatggt ctcgccgtac ggggccagct cgttctcgtc
     9481 gatgcacttg cgcagctggt agacgtaggt gtgcatggtg gtgcggacgc tgcgcggcgg
     9541 gtcgttggcc cacagttcct gcacgatcgt gtcgatgtgc acgatcttcc ccgggctcat
     9601 gaccagcatg gcgagcacct gcagcagctt cggcgtcgtc ggcgcgtagt cgatcccgtc
     9661 ccgcacgagt tcgagcgggc cgagcaggct gaagcggacg gggcttgcgg acgcggccgg
     9721 aatcgggttg ggtgccgagc cgtggtgctt gtccgctact cgtgatccgg tgtacatcgc
     9781 aagcgccctc cagctcgata cgcgtcgtga cctgaatccc agtgcttcga cagtgacaga
     9841 gcggccggtc gccgggccag tgagccgtcc accagggccc gcatgcgtgt ctcccggaag
     9901 aacatgggtt tttcacatcc gacgcgtgaa tcgcacactg gccgctcacc ggccccacac
     9961 agcaggattc gagaatcgaa ccgacctact gggggtcatc atgcgcgagg catcgaccac
    10021 acccacctcg atcggcggac tgggattcaa gcggcatctg cgtgcggaga tcagcgaggg
    10081 caacggtgcc tacctgttct ccgaacaggg ggtcatcgcc atccgcggcg cacaggtcgc
    10141 gtcggtggcg gccctgctcg acggcacccg tgacctcgac gggctcctgt ccgcctgccc
    10201 ggaggggatg aacgccgaac aggtcaccgg cgtggtggcc cggctggtcg aggccggtct
    10261 ggtgaccgtc cgcgtcccgg acgagttcag cggggacgag cgcgcgctcg cgtactggga
    10321 cgcgtgcggg ctcgacgcgt ccgcggtggc ctgccgtcag aagccggcga cggcgagcct
    10381 gaccgcgatc ggccgcggcg tcgatacgtc gcaggtggct aacgcgctgg ccgcgagcgg
    10441 gatcgaagtg gtcgagacgg cgtccgagct ggccatcgtg ctgtgcgacg actacctcga
    10501 cccgaggctg gccgggatcg acgccgagca ccggcgcacc gggcggccct ggctgctggc
    10561 acggccttcg ggatcccaag tgtggatcgg gccgatcatg cagcccggcc ggtccggctg
    10621 ctggcactgc ctgacgaacc ggttgtgggg gcaccggcac gccgaggcct gtgtgcagga
    10681 ggtgctgggg cacgacggtc ccgcgtcgtt cccgatgccc gccgtgccgc cgctgaccgc
    10741 ggccgcgtcg cacctgatct cgctcgaagc gtccaaatgg ctggcagggc accgctatcc
    10801 ggggcagcag gccgtgtgga tcctcgacac cctcgacctg caggggcggc tgcacgaact
    10861 gcggcgccgc ccgcaatgcc ccgaatgcgg tgacgaaggc atcgtcgccg cgcagacggc
    10921 cgaaccggtc gtgctgcggg aggcgaagaa ggcgacgtcg ggcggtggcg ggcaccggac
    10981 gctcaccccg gtcgaggtgc tcgaccgcta cggccatctg gtcagcccgg tcaccggcat
    11041 cgtcaaggag atcgcccgcg acccgagggc gcccgcgttc gtgaacgcgt accgctcagg
    11101 gctgaacgtc gcccgccgtg tgcgcggcga ggcgggattg caggccgggc tgcgcgggga
    11161 caacggcggc aagggcgcga gcccgatcga cgccgaggtc ggcgcgctgt gcgaggcgat
    11221 cgaacggttc tcggcgaact accagggcga cgaactgcgg atccgcgaca ccttccgcgc
    11281 gctcggtgac gacgccgtcc acccgaacac gtgcatgctc ttcgacgagc gccagtacga
    11341 aacgcgcgtc gactggaacg ccaggcacgc gaacttccag cacgtccccg accggttcga
    11401 caccgaggcg gccgtcgact ggacaccgct gtggtcgctc tcgcagcagc ggcggaagct
    11461 gatgccgacg gcgtacctct actacggggt gccgccggag tgcgggctca ccgggatgcg
    11521 cgcggactcc aacggctgcg cggccggcag cagcgtcgag gacgcgatcc tgcagggcct
    11581 gctcgaactc gtggaacgcg acgccgtcgc gatgtggtgg tacaaccggc ttcccgtgcc
    11641 cggcgtcgac atcgcgtcgt tcgacgaccc gtgggccgag gagatggtcg gccagtacgc
    11701 gcgggcaggc cgggagctgt gggtgctcga cctgaccgcg gacctcggtg tgccggtgat
    11761 ggtcgcgctg tccaggagta tcgccgggcc gcgcgagaac gtcatgatgg gcttcggcgc
    11821 ccacctggac cccaggacgg cgttgcggag ggcggtcagc gagctcaacc agatgatccc
    11881 ggcggtgctc gcgaacgacg tcgaactcga cgatcccgac gcgtcggcgt ggctcaagta
    11941 cgcgaccgtc gggaaccagc cgtatctgct gccggcgccg gggcggtcgg cgaaacgcgc
    12001 cgcggacttc aagttcgtcc ggcggcccga tgtccgtgac gacgtggagt gcttggtccg
    12061 caagctttcc gcgctgggaa tggagacgct cgtgctggac cagaccagac ccgacatcga
    12121 cctcccggtg gtccgggtgg tcgttccggg gctgcgcccg ttctggagcc gcttcgcccc
    12181 cgggcgcctg ttcgacgtgc cggtgcggct gggcaggctc gccgagccga ctccctacga
    12241 ccggctcaac ccattcccca tgttcttata gagcgctctg gagcaaccgt tgacgacaga
    12301 tccccccggc ggagtggccg aaacgatccc cttgtggtcg ctcaccgacg acagccttgt
    12361 cgagatcggt gaggacggct cgctggtggt cgtcacccgc tggggcgagt acgagttcga
    12421 ccgcgcggaa ccgctggtgc tggaatcgtt gcggcggatg gcgttggggc cggtctcgct
    12481 ggcgaacgtg acgtcttcgt gggagccctt cgaacgggag cccgacctcg aaggcgaact
    12541 gagctggacg gccgaaggcg ccgacgcgtt gcggcaggta ctcaaggaac tcggtggttc
    12601 cgtggtgcgc tcactcgggc tcgccgacgg caggggaccg ctgctgtcgg tgataccggt
    12661 cgtgctcgcc ccggtgttcg cgccggtgga gatcccgccc acgcgcccga tccggttgtc
    12721 ccgcttcagt tccctgcggt ccgacgcgga cgggatgggg ctggagtcgc cgtccgcgcg
    12781 ctaccgcgtg gtgctgtccc agccgtgggc ggtgcatgtc gcggcgacac tggcgacggc
    12841 gaaatcggtc cgggacatcg tgtccaccac cgggatcgac gcctcggtgg ccggcgcgat
    12901 cgtgtcctat ctggtcgccg cgggtgtcgt ccaggtggcg ggcgaagacg gccggttcgc
    12961 cgaggacgac gatcccgaac tgagcctgtg gtcgccggac gaactctcgt tccacaccac
    13021 cagccgcacc tggcggcccg gcggcccggc ggatctgccc ggtctcggga aaccgccggt
    13081 ggtcaaggcc gccaccggcg aggggccggt ccacccgctg taccggccgg atctggccga
    13141 ccgcgcggtg accgacccga cgctgacgac gttgctggag aacgaccaca cctgccccga
    13201 attcaccgag ggtgtgctga ccgccgagca gatcggcgag ttcctgttcc gtggcgcgag
    13261 aatccggtcc atcgggcccg cgcacctgcc gaacgggccc gcgcacagtg cttcgcagcg
    13321 gccgtacttc agcgtcgcct gcctgtacga actcgagttg tacgtctccg tcaaccgttg
    13381 ctcggggctg gatcgcggga tctaccacta cgacccgctg gagcaccggc tcgccctggt
    13441 gaacgccgac gaggccgacc tcgacgcgat gctcgacatg gcgatgatcg gtggcggcaa
    13501 ccatcggcgg ccctcggcgc tgatcaccgt gaccgcgcgg atgccgcgga tggcgtccgt
    13561 cctcggtggc ggcgcgtacg ccaccacgct ggcgcacgtc ggtgcgctgc aacagacgct
    13621 gtacctcgtc gctcgagcca tggggctggc cgcgcacgcc gtcccggtgg acgccggcga
    13681 ccgcgtcgat cgcgcgctga agctcgactg gcccgccgag gtcagcgtcg gcgagtgcgt
    13741 cctcgacctc ccggtctgac ccttcgtgca cccgcgcgtg actcgcgtga ttggagacgt
    13801 gactcgcgtg attgggcgcg aaactcgatg atcgccctct gatcacgcga gttccgtgcc
    13861 caatcacgcg tgtcacgccc tggatcacgc gagttcggcc ttgcggatct cgatcgctcg
    13921 tcgagtgcac tgaaatcgac accgcgtttg ctggcgtaca gaggaaaagc gacagcgaat
    13981 ccgaggttgg tctgatgcag ctacgaacag tcgccatggc ggcgaacgag aaaggcgtca
    14041 ccgaacccgg tcggctcccc gagccggcgt cccccttgca acctgcggtg ctgcaggcca
    14101 tctcatcgat gcacgcgagg tacttcgacc cgatcacctt gggcgacctg gcatcggaag
    14161 tcttcgtcag cccgttccac ttctcgcgga tcttcaccaa ggcgaccggg atcacccccg
    14221 gccggtacct caccgcgatc cggctcttcg aggcgaaacg actgctgctg acgacatcgc
    14281 tgacggtgtc ggacatcgtg tgcagcgtcg gctacagcag tgtcggcacg ttcaccagcc
    14341 gcttcacccg tgcggtcggg atgaccccga cccagtaccg cgatcccgag gtcggcgagc
    14401 tgctcgtcgc gctggccccg catttccagc gcctcccgac gctggaagcg ttgcacagtg
    14461 ccggaatggg cagcgccacg atgcgcagcg gcaccggcac gatcagcgta cgggtcgaga
    14521 ccccgcgcgg ggcgggcccg gcgagtgtcc tcatcggact gttcgccgag tcgatcccgc
    14581 agtgcggccc cgtcgccttc gggggcaggg cgaacgtcct gtccgcggac atcgagatcc
    14641 agaacgtccc tgagggacga tggaccgtca tcggggtggc cgagcacgcc gccgggaccg
    14701 cggcctcctc gttctccgtg ggcacgctgc ccggccgcgt cgacatcacc cggtacggca
    14761 gggtccacct gaggatgccg atgcgtgccc cgcggcccac cgacgcgccg atggcgatca
    14821 ccctcgccgg cggtccgagc tccgccggga accggatgac catgcccgct cccgagtacc
    14881 tccgcgcggt ggcctgaccg agttgttccc gcggtctccc gatcccgcaa accgggagaa
    14941 ccgcgggcgc aaccgtggag tggtcgcgtg atcggcacgc atgtgagcct ttaagcaatc
    15001 cggaattcga atccacccgt tagggggaga gtgcgttggg caatggttgg cgcacgatca
    15061 gacgtcgcat gatcacgccg gacgtctccg agacgtcact ggacaagcgc ggtttccaca
    15121 agaagagccc ggccgctcaa gaattgctgg agaccgtcgg tgagaagttc ctgctcggct
    15181 acgcgcacgc ggtcgaagca cggtccgtcg aacaggcgga agaatggctc gaacagattc
    15241 cggtgaaata ccgcggtttc gcctacgaag gcgcgggaat gggttacgga atgctggacg
    15301 ggctgccggg cggcggccgc cgccacgtcg aacggttcct cgacggcccc ggcgagaagc
    15361 acgactacat catctacgtc ggcgtcggct gggcgatggc gcgcctgccg cgcttccgct
    15421 ggccgtccgc cgaggacttc gacccgttgc tgcgctggct ggtgctcgac ggctacggct
    15481 tccaccaggc ctacttcaag acggcgaaat acgtcgacgg gcagttccag gacccggact
    15541 tctcctggcc gcccgggaac gacggctacg cgctgcgggc gatcgaccag ggcatcgggc
    15601 gggcgctgtg gttcatctgc ggcaccgacg tcgacctggt cgccgacacg gtcgcgcggt
    15661 tcccggaacg gcggcacgga gacctgtacg ccggtatcgg gctcgcctcg acctacgcgt
    15721 gcggtgtcac cggtgacgaa ctgctgaagc tggccgagtt cgccggtgag caccgcggga
    15781 acctcgccca gggcagcgct ttcgccgccg aagcccgcgt ccgcgccggg ctgctgatcc
    15841 ccgagaccga ggtcgccacg cgggcgatct gcgggctgcc ggccgagcgg gccgcggcca
    15901 tcacccagga ggtgcgcccg gcgaccgtgg tcgacggcga actcccggca ttcgaaacct
    15961 ggcgacagcg catcgccgaa gcgattcttt ctggaggtgc agggaaatga ccgcgacctt
    16021 gggctggctc cgcaagcagc ttgcgggcat cgtggcgctg gtgctgatgg cgggactgtt
    16081 cgtggtggcg cagctgccca ccgtctcgac cgccgaagcc gacaccatgg cttcgaagta
    16141 cgcgttcgag ccgctgacga tcgccttgcc ggaagcggcg aagagccagt cgatccggac
    16201 ggtgaacaag gagtacgagc acatccgcgc ctggatctcc tcggtcggcg ccgcgatcgc
    16261 ggtgaacgac ctcgacggcg acaagctcgc gaacgacctg tgcttcgtcg atccgcgcag
    16321 cgaccaggtc gtcatcaccc cgacgccggg caagggcggc gaccgctacg cgccgttcgc
    16381 gctcgacgcg gcaccgttgc cgatgggcaa gtacatcgcg cccatgggct gtgtccccgc
    16441 ggactacaac gaggacggcc gggtcgacct gctggcctac tactggggcc gcacgccgat
    16501 cctgttcctc tcgaagccgg gcgccacgaa gctggagccg aaggcctacg agccggtgga
    16561 actggtgccg ggcaacaact ccaagaacgg cgagtactcc ggtccactgt ggaacaccaa
    16621 cgccgcctcc gtcggtgact tcgacggcga cggccaccag gacatcttca tcggcaacta
    16681 cttccccgac agcgcggtgc tggacgaccg cgtctccggc ggggtcgaga tgaacaagtc
    16741 gatgtcgcac gccgacaacg ccggcggcaa gtacatcctg aggttcaccg gcgccacgca
    16801 gggcgcgaag ccgagcgcga cgttcgccct cgacgacaag gccatcccgg ccgactccca
    16861 gggcggctgg tcgctggcgg ccagcgccac cgacgtcgac ggggacaacc tgcccgagct
    16921 ctacatcggc aacgacttcg gccacgaccg cctgctgtac aacaagtccc gccccggtca
    16981 cgtcgaattc gccgaggtga agggcatccg cgggcccaac gagccgaagt ccaaggtgat
    17041 cggcaacgac tccttcaagg gcatgggcgt cgacttcgcc gacctcgacc acgacggtct
    17101 ctacgacctg tacgtcagca acatcacgac ctcctggggt atcgaggaaa gccacttcca
    17161 gttcatgaac accgccaagg acaccgcgga tctgcgtggc cgtctgcagg gcggcgaggc
    17221 gccgtgggtg gaccgcagcg cgcaggccgg caccgcctgg tccggctggg gctgggacgt
    17281 caagatcgcc gactacgaca acagcggcga atcggtgatc acccaggcga ccgggttcgt
    17341 caagggcgac gtcaaccgct ggccgcagct gcaggagctg gcgacgtcga acgacgaact
    17401 gctgaagcac ccgtacttct ggccgaacat ggtcgccggt gacgacgtcg gtggcgacca
    17461 cacgctgcac ttctgggcca agagctccga cggccgctac accgacctgg ccccgcgcct
    17521 cggtctcgcg gtcccggtgc ccacccgcgg tatcgccacc ggtgacgccg acggcgacgg
    17581 caagctcgac ttcgccgtgg cccgccagtg ggaacagccg atcttctacc gcaacgtcag
    17641 ccccggcacc gggtcctacc tgaacctgaa gctggtacac gacaaggctt cggcggacgg
    17701 tccgctcaag gcggccggta ccgcggcgat cggcgcgcag gtcaccgtcg tcacccccga
    17761 cggcaagaag tacatggacc gcgtcgacgg cggcagcggc cactccggca agcgcagcca
    17821 cgagatccag atcgggctgg gcaaggtcac cgggccggtg aaggtctgcc tgcagtggcg
    17881 cgacctgacc gggcagatcc gcacgcagga agtccagctg accccgggcg accacacgtt
    17941 ccagctcggc gctcaggcta aggagaaatg accgtcatgg ctgagcagac actcaccgca
    18001 ccgaagagca acaagacgat cacggcgctg cgccggttcg cgatctcgat caccatcttc
    18061 aacatcatcg gctacaccgt gctcggtttc gagcagccct acacttatcc gttcatcgcg
    18121 ctggccacgg cgtacgccac ggaaatcctg ctggagatca tcggggcccg cgcacagggg
    18181 cgcggcgtcc gcttccgggg caacgggttc aagggactgg tggagttcct cttccccgcg
    18241 catatcaccg gtctcgcgct gaacatgctc acctacgtca acgaccaggt gctggtcatg
    18301 atgttcggcg tcgtggtcgc cgtcggcgcc aagtgggtcc tgcaggcccc ggtgcgcggc
    18361 aggctccgcc actacatgaa cccgtcgaac ttcggcatca cgatcatcct gctggtgttc
    18421 ccctgggcga gcatcgcccc gccgtatcac ttcaccgagc aggtcgactc gtgggtcggc
    18481 tggctgatcg tcggcatcat catcgtctcc ggcaccgtgc tcaacgcgat gctgacccag
    18541 cgcatgtggc tgatcggcgc ctggctgatc accttcgcgc tccaggcgat catccgtggc
    18601 ctggtgttcg acaccgcgat cccgggcgcg ctcgggatga tgaccggtgt ggcgttcgtg
    18661 ctctacacga actacatggt caccgacccg gggacgaccc cgtccaagcc cgcgtcgcag
    18721 atcctgttcg gctcgggagt ggcgctggcg tacgggttct tcatggtcgt gcacgtggct
    18781 tacggtctgt tcctcgccac cgcgctggtc tgcctcatcc gcgggatgtt cctgtggggc
    18841 ctgcacttct ccaagaaggc caccgagaaa tgggaggccg agcaggcgaa gtcggccgag
    18901 atcacctcct tgccgaagcc ggccgagaag ccggaaaccg gggccgtggc ggcatgaccc
    18961 ccggtgcgga aagcagccgg gcggcgcgtc tcgcgccgcc cggcccgccg cgccgggcga
    19021 ccttcggtct gctgaagaag ctcttcaccg atcggctggc gctcatgtcg gactcggcgg
    19081 aggcacacgg ggacgtcgtc cggatcgcga tcggtcccaa gacgatgtac ctggtgaacc
    19141 accccgaact ggcgaaacac gtactcgcgg acaacgcggc caactaccac aagggaatcg
    19201 gcctccagga ggcgagacgg gcactcggcg acgggttgct caccagtgac ggcgacgtct
    19261 ggaagaagca gcgccggacc atccagccgg tgttccagcc caagcggatc gcacggcagg
    19321 cctcggtcgt cgcgaacgag gtcgaaggac tcgtgaaacg cttgcgggac accgagggac
    19381 cggtggagat cctgcacgag atgaccgggc tgaccctcgg cgtgctcggc aagacgctgc
    19441 tcgacgcgga cctgggcggg ttcacctcgc tggggcactc gttcgaggcg gtgcaggacc
    19501 aggcgatgtt cgaagcggtg acgctgagca tggtcccgca gtgggcgccg ctgaagaaac
    19561 agctgcggtt ccgggaatcg cgggacgacc tccgccgcat cgccgacgaa ctcgtcgagc
    19621 agcggctggc caacccggtc gagaacggcg aggacgtgct ttcgcgcctc atcgccaccg
    19681 acgggacccg tgggcagatg cgcgacgagc tgatcacgct gctgctggcc gggcacgaga
    19741 cgacggcgag cacgctgggg tgggcgttcc atctgctcga cgagcatccg gagatcgcgg
    19801 cgaaactgcg tgccgaggcc gacgcggtac tgggcgacca gctgccgacg cacgaggatc
    19861 tgcatcggct gccgtacacg gcgagggtcg tcgaagaggt catgcgcctg tacccgccgg
    19921 tgtggctgct gccgagggtg gcgcaggccg acgacgagat cggcggctat cacatccccg
    19981 ccggatccga cgtcgtcgtc gtgcccttca ccctgcaccg gcatccggat ttctggccgg
    20041 agccggagag gttcgatccg gaccggttcg acccggaccg gccgagcggg cggccccgct
    20101 acgcctacat cccgttcggc gccgggccgc ggttctgcat cggcaacagc ctcggcgtga
    20161 tggaggccgt cttcgtgctg acgatggtcc tgcgcgacct cgaactcaga aagctcccgg
    20221 gctacgacgt ggttcccgag gcgatgctgt cgctccgggt gcgcggcggg ctgccgatga
    20281 ccgtgcacac caggaacagg aggtaggttc cgtggattcg gacgaacagg tcgaggtgtc
    20341 cactttggag gcctacgcgg acacgatcgt gccgggggag aagcgtttcc ccggcgacca
    20401 cgccatcgcc ggcgcttcgc cggggccggg cgcggtcgcg gcgggcgcgc tcgaactgct
    20461 gcacaccgag gcgaccgggg tgaccgtcgg gctgccctat ctggcgcagt ccctcaacga
    20521 ccacgcgaag gtctacgcca aggaacacga catcacgctg gacgagtcgc tgccggcgtt
    20581 cgtcgcattg tccttcgcgg acaggacggc gctcgtgcgg tcgctgaccg cgccgggaca
    20641 tccggagaag gacggctggg tcagcctcgc cttgttctgc aacatgtcct tcgacagcgc
    20701 cgcgcacaag cacaccgccg aagccatcgc cgagggtcac cccggcctgc tggcgatggg
    20761 gtacaccgcg ccggacgaag acggtctgtg gcggttcccc aagttctcct accgccgcga
    20821 gctggcccga gtccaccccg acaccacgcc ttccgggagt cccgcatgac cgcctacgac
    20881 aagaccgacg tcgtcatcgt cggcagcggg ttcggtggct ccatccccgc ctaccacttg
    20941 gccgcgggcg gggcgaaggt caccgtgctg gaacgcgggc cgtggctgga gacgaaggag
    21001 ttcgagcacg actatctgct cggctcgtcc tacacccggg ccttcgattt cgtcgtcggc
    21061 gacgggatga gcgtgctcgg cgggaactgt gtcggcggcg gcagcgtggt gtacttcgcc
    21121 gcgatgcccc gcgcgccgaa gttcgtgttc gaacggcacg ggagcatcgg ccgtcgcatg
    21181 tggccttcgg tgctgacgcg tgacaccctg gaaccttggt acgatcgggt ttcggagtcg
    21241 cttccggtgt ccacacagga ctggaacgac gtctcgtacg cgggcgggct gtgggcggcg
    21301 ttctgcaacc actccggccg gaccgccaac cccgcgccgg tggcggtgga caacgaccgc
    21361 tgcgtgaact gcaacttcat gatggcgggc tgccggttcg acgcgaaacg ctcgctgctg
    21421 accaactacc tgcccgcggc gctcgcgcac ggcgcgaaga tccggccact gcacgaggtg
    21481 cagcggatcg agcggatcga cgacggcgac taccgcgtgc acttcaacat cgtcgacgac
    21541 gaggactacc ggctccagtc cggcagcggg acgatcgacg cgaagatcgt catcatcgcc
    21601 gcgggcgccg gcgcgacacc ggtgatcctg cagcgttcgg aggcggcgct gggcaccatg
    21661 ccgcacgcgg tcggccggta cttctcgggc aacggggagc ggctcaacac cgcgatcatc
    21721 aacgaggagc gcgtgcgcga ggtgctcggg ctgtcccgtg aagacgggaa ggtctacgag
    21781 gccaaccaca tcggcaaggg cccgaccgtc gcgaactggg acaagctcga cggctcgctg
    21841 ccggagtacg agcggtattc gctggagcag ctgtacttcc cgcccgggct cggcacgatt
    21901 ctcgcgcagg tgcccgacgg ggacgagcct cgctggttcg gagtgcagaa gaaggagatc
    21961 ctcaagaagt gggcctcctg gctgaccatc ttcctgatga ccgaggacga caacgagggc
    22021 gtcttcggcg cgccgccgcc caccggcaac gcctaccgca tctcgcagca gatgctcggc
    22081 cgcggtccgc tgaagtacga cccgacgccg aacacccggc acggctgggc gctggccgac
    22141 gcggagtgca aggagatcct cgagaaggac ggcctggcga aggtggcgcc gtggaccaac
    22201 gacgtcgtcg gcgcgtacac cgtgcacccg ctggcgtcgt gccggatcgg tgacgacccg
    22261 gcgacctcgg cgctgcaccc gaaccacgaa ctccgcgacc accccgggat cttcgtgacc
    22321 gacagcgctt ccgtaccggg cgcgctgacg gtgaacccgg cgatgacgat cgcggccctg
    22381 gccgagcgtt cggtgccggg gatcgtgcgg gcgttgcagg ctcgcggtgt cgacgtcacc
    22441 tacggcgctc ccgccccgga cggttcgatc acggggcggc gggccgtcgg caagctgtcg
    22501 ctggtggccg ggagctgagc gtggcacccg tgctggtgaa gctcgcgctg cggcgcgcgg
    22561 tgcgtgaagc ccggtacgtc cggccggtgc ccttcggccg ggcgaccggg ctcgtgcgcg
    22621 acgtctacgg acggctggaa cgcgatttcg ggatgctggc cccgccggtc gcggtgcatt
    22681 cgccgtcacc gccggtgctc gcggcgagct gggtgatgct gcgggaatcg ctggtggcgg
    22741 cgggggagac gagccgggcg gaccgggaga tcgtcgcgac ggtggtgtcg cgagggaact
    22801 cgtgtccgta ctgtgtcgag gtccacggga tggcgctgga ctcgctcggg cgctctgtgg
    22861 aggccgcggc gatcgcctcg gggcggcccg tgacggatcc tcgtacggga atcctttcgg
    22921 cgggggcccg ggcggagctg accgcggtcg cgttcacgtt ccactacctg aaccgggtgg
    22981 tgagcgtttt cctcgggccg tcaccgctgc cgtcgtccgt gccggattcg gcgcgggcga
    23041 aggcgaaggc cgtcttgggg cggttccttc ggccggtgac cggggccgcg ccgggggagt
    23101 cgctggacct gttgccggtg ggctcccggg atttcgcctg ggccgcgggc aatcccgtgg
    23161 tcgaggacgc gttctcccgc gccgcgtcgg cgttcgccgc gttgccggtg ccttcgtcgg
    23221 tgcgggacgt cgtggagcga gaactgtcta cttgggacgg tgcgccaccc gggttgagcc
    23281 ggtcctgggt ggaggccttc gacgatcccg cggtccgttt ggccttggtg gtcgcgaagg
    23341 cgccttatca ggtggacgac gctttggtgg cggcggcggg actgggagac cgggaactgg
    23401 tcgagttggt ggggtgggcg ggtttcaccg ccgccgcccg cgctgtttcg gtcgccccgc
    23461 ttcctggtta gtgcggagta ctgcctgttt atgacgcgaa agccactttc gcaacgttca
    23521 acgttgcgga agtggctttc gcgtcgtcgg tgggtgccgg cggaaaacgt ggtcggcgcg
    23581 ggtaagtgac cggtatgaag gctcccttca ccgcgttaga cgcggcgaag ggagccttca
    23641 ccccaccacc gaccaggccg cgggactccg ttgaccgcca tcgcgaacgt gccagggccg
    23701 gatcactcgg gcggatgacc gatcccggtc aacaacttga gagaagactc cgcgtccgcc
    23761 cccggttcat gcttgaccgg actgcgcgaa cggacggcgg ccgcgtatct ggggacagaa
    23821 ccggcgccgg gaccggattc cgtgacttga gtggttgaga gctaggggag tgcggtggca
    23881 tgagcgttga gcggatttcg attgtcggta tcggtctccg atacccggac gccggttccc
    23941 cggaagagct gtgggagaac gtcctcgccg gccgccgggc gttccggagg ctgcccgacg
    24001 agcggatgaa ccgcgaggat tactactcgc ccgaccccaa ggctccggac cgtttctacg
    24061 cccagaaggc cgcggtcctc cgcgactacg aattcgaccg gatcaagtac aaggtcgcgg
    24121 gcagcacgtt ccgttcgacc gacaccacgc actggctggc cctcgacgtc gccgcgcagg
    24181 cgctggccga cgcgggcttc cccgagggcg aggggctgcc gaagcccgcc accggcgtgg
    24241 tcatcggcaa cagcctcacc ggcgagttct cccgtgccaa catcatgcgg ctgcgctggc
    24301 cgtacgtgcg ccgcacggtg gcggcggcgc tcgccgagcg cggctgggcc gacggcgaca
    24361 ccgccgagtt cctccacgat ctcgaggcgc agtacaaggc ccccttcccg gagatcgacg
    24421 aggacacgct cgcgggcggg ctggcgaaca cgatcgccgg ccgggtctgc aacttcttcg
    24481 acttcggcgg cggcgggttc actgtggacg gtgcctgttc gtcgtcgctg ctttccgtgg
    24541 tcacggcggc gaacgcgctt tcggagggcg acctcgacgt cgccatcgcg ggcggtgtcg
    24601 acttgtcgat cgacccgttc gaggtgatcg ggttcgccaa gaccggcgcg ctcgccaaac
    24661 gcgagatgaa ggtctacgac gccgattcca acgggttctg gcccggcgag gggtccggca
    24721 tgctcgtgct gatgcgcgag gaggacgcga tcgcgcaggg caagcggatc tacgccacca
    24781 tcggcggctg gggcgtctcg tccgacggca agggcggcat cacccgcccc gaggcctcgg
    24841 ggcaccgcct cgcgctcaag cgggcgtacg acaaggcggg gtacggcgtc gagaccgttt
    24901 cctacttcga gggccacggc accgggaccg cactgggcga cgccaccgaa atcgaggcgc
    24961 tctccaccgc ccgccgcgac gccgatccgc tcgccgagcg ggccgcgctg agcacgatca
    25021 agggcaacat cggccacacc aaggccgcgg ccggggtcgc cgggctgatc aaggcgacct
    25081 tggcggtgta ccaccaggtc atcccgcccg cgaccggcca tttcgaaccg cacgagtcgc
    25141 tggtcggcga ctcggcgcgg atgtacgtgc ccgccgaggc cgggctgtgg ccctcggacc
    25201 agccggtccg cgccggtgtc tccgcgatgg ggttcggcgg catcaactcg cacgtcaccg
    25261 tcaccgaagc gccgggcgcg gcccgtcgca aggagctcga cgagcggacc aggtcgctgg
    25321 tcgccggacg gcaggacagt gaactgctgc tcctcgacgc cgacgacgcc gcgtcgttgc
    25381 gtggcaaggt gaccggcctg ctggaggtcg tcccgaagct ctcgttcgcg gaactcgcgg
    25441 acctcgcggg cacgctttcg gccgagctgt ccgggaaacc ggtccgggcg gcggtcgtcg
    25501 cggccggacc ggacgacgcc gagcgcaaac tggccaaact cctcgacctt ctcggtgagg
    25561 gggagccgga agtcttctcc gccaaggaag gcatcttcgc cggatcccgc tcccagtccc
    25621 cgaagatcgg gttcctgttc cccggccagg gttccgggca gggcagggtc ggcgcgctgc
    25681 gcaaacgctt cgcgcacgcc gacgacatct accgcgccgc gaacctgtcc accggcgccg
    25741 accaggtcgc caccgacgtc gcccagccgc gcatcgtcac cggttcgctg gccgggctgc
    25801 gggtgctgaa gagcctcggc atcgaggcgg ccacggtcac gggccacagc ctcggcgagc
    25861 tcaccgccct gcactggggc ggcgcgctca ccgaacgcga agtgctcaaa ctggccaaga
    25921 tccgcggcaa ggtgatggcg accgccagcg acggggacgg ggccatggcg gcgatcgcgg
    25981 ccacgccgag tgtcgccgag ggcctggccg agggcgaaga ggtcgtcatc gcgggctaca
    26041 acgcccccga gcagactgtc ctttccggac cggcggaggc gatcgaccgc gtggtcgccc
    26101 gtgcccgcgc ggaaggggtc accgccgccc gcatcaacgt ctcgcacgcc ttccactcgc
    26161 ccgcggtcgt cccggccgcc gaggcgatga ccggggaact cgccgcgatc gacttcgcgc
    26221 ggctcgaccg gcccgtcgtc tccacggtga ccggtgacgt cctgcacgcc gccgaagacc
    26281 tgcgcgatct gctgcgcgac caggtggtcc tgccggtccg cttccgtgag gcggccgcga
    26341 aggtcgccga gcgcagcgac ctggtgatcg aggtcggccc cggccgcgtg ctcaccggcc
    26401 tgctcggcac catcgcgccc ggtaccccgg tgctttcgat cgacaccgac agcctgacgc
    26461 tcgcgccggt gctgaaggtc gccggtgccg cgttcgcgtt cggcgcgcag ctggagacgt
    26521 ccacgctgtt cgacggccgg gtcgtgcggg ccctgcccgc ggacggcgag ttctcgttcc
    26581 tcgccagccc gtgcgaggcc gcgccgtcca tcggcgccgt gctgacccgc gaccgagtcg
    26641 ccgagcccgc cgaggccgcc gccggaacgg cctcggaaag cggtggcagc agcaccctcg
    26701 acctgctgcg caagctcgcg tccgaacggg tcgagctgcc gctcgaagcg gtcaccgccg
    26761 acacgcatcc cctcgacgat ctgcaccttt cgtcgatcac cgtcggccag ctggtcaacg
    26821 acgtgaccag ggcgctcggc cggccggcgc tggagggtat gccgaacttc gcgaccgtgt
    26881 gcctcggcga actcgccgag atgatcgacg agctcgcgca gaccgccaaa cccgccgaca
    26941 gcaaccaggc cgaggtcgcc ggcgtcggcc cgtgggtccg gccgttcgcg gtggagtacg
    27001 tcgtcgcgcc gaagccgtcg cccgatctcg ccacgggtat ctccaccgcg gagtggacgg
    27061 cgttcgcccc ggccggtcac ccactggcgg agccgctgcg cgcggcattg gccacggcgg
    27121 gcgtcggcga cggtgtcctc ctctgcctga acgccgacag cgcttccggc gacgtcggcc
    27181 tgttcctgga cgcgggccgc gcggtgctgg ccgcgcccaa cggcacgcgg ttcgtcgtgg
    27241 tgcagcacgg tctcggcgcc tcggggctgg cgaagacgct ccggctggag gacccgtcgg
    27301 cccgcaccac gatcgtcgac ctcgccgacc tcggcccggt cgaccccgaa gccctcgacg
    27361 ccgcggtgtc cactgtggtc accgaagtgg cggcgacgac cgacttcagc gaagtccgct
    27421 acgacaccgc cggagtccgc acggtgccga agctcgcggc gctgaccccg gccgaggccg
    27481 aaggcacccc gctggacacc ggcgacgtcc tgctcgtcac gggcggcggg aagggcatca
    27541 ccgccgagag cgcgttggcg ctggccaagg attccggcgc gaagctggca ctgctcggcc
    27601 ggagcgaccc ggccgacgac gccgaactgt cggagaacct cggccgcatg gcggcggcgg
    27661 gcatcaccta ccgctacgag cgtgccgacg tcaccgacgg acggcaggtg gccgacgcga
    27721 tcggccgggt gcaggccgaa ttcggcccgg tcaccgcggt gctgcacggc gcgggccgca
    27781 acgagcccgc cgcgctgttc tccttgaccg aagagagctt ccgcaagacg ctggcgccga
    27841 agatcggtgg tctcaacgcc gtcctcgacg ccgtcgacaa ggacaagatc aagctgctgg
    27901 tgaccttcgg cagcatcatc ggccgggcgg gcctgcgcgg tgaggcgcac tacgccacgg
    27961 ccaacgactg gatgaccgaa ctgaccgtgc ggttcggcca ggaacacccc cgggccaagg
    28021 cgatcgcgct cgaatggtcg gtctggtccg gcaccgggat gggcgaaaag ctcggtgtgg
    28081 tcagcgcgtt gatgcgcgac ggcatcaccc ccatcccgac cgaggagggc atcgagatcc
    28141 tccgccaggt cgtcggcgac ccggccgccc cgtcggtact ggtcgtctgc ggccgcaccg
    28201 ccgggctggc cacccttccg gtggagaagc gcgaactgcc gctgacccgc ttcgtcgacc
    28261 gcgccgtcgt gcactacccg ggggtcgagc tgatcaccga ggccgacctg tccgcgggca
    28321 gcgacccgta tctggccgac cacctgctcg acggtcagct gctgttcccg gcggtgatcg
    28381 gcatggaggc gatgacccag gtcgccaagg ccgcgctggc cgcggaaacg ctgccggcgc
    28441 cggtgttctc cgacgtcgag ttcctgcgcc cgatcatcgt ctcgccgggc gggtcgacca
    28501 cgatccggct cgccgcgctg gccagggacg ccgaaacggt ggacgtggtg ctgcgcagcg
    28561 gggagaccgg cttcagcgcc gaccacttcc gggcccggct gagcttctcg cggccggatc
    28621 cgctcggtga caccgtcgcc cgcgacgtcg cgctgccgcc ggtgccggtg gacccgacga
    28681 ccgagctcta cggcacggtt ctgttccagg gcaagcgatt ccagcgggtc accggatacc
    28741 ggcgggccag cgcgcggcac gcggtcgcgg aggtcgccac cggtgccgag gtcgactggt
    28801 tcgcgccgtt cctcccgcag gagcagctcc tggccgaccc gggcacccgc gacgcgatga
    28861 tgcacgcgat ccagtgctgt gtcccggacg cgaccctgct gccgcaaggg atcgagcggc
    28921 tgtacctcgc cgaacccggt gagcagcacc cggagtacgt gctcctcgac gcccgcgagc
    28981 gttcgcagga cggtgacagc tacgtctacg acctcgacgt ccgcaacccc gacgggaagc
    29041 tggtcgagcg gtgggaaggg ctgaagctgc gcgcggtgcg caagcgtgac ggcgaagggc
    29101 cttgggtccc gtcgatgctc gggtcctatt tggagcgttc cgtcgaacgg ctgctcggct
    29161 cgtcccgcgc gatcgtcgtc gaaccggatc cggtgggcgt tcccgtggag accacgccgg
    29221 agcggcgggc gcagacggca ctggccgccg gccgagccgt cgacgcgccg ctggagatcc
    29281 gctaccgccc ggacgggaaa ccggaggccg acggggtcga ggtgagcgcg tcgcacagcg
    29341 ccgacctcac cctggccatc gcgggcgccg gacggatcgc gtgtgacgtc gaaacggcga
    29401 tcgaacggac gccggaggac tgggccggcc tgctcggcga ggatctgctc gcggtgggcg
    29461 aactgctggc cgcggacgcc cgcgagccgc tttcggtggc gcacaccagg gtctggagcg
    29521 cactggaatg cgtgcgcaag accggggaca tgacacaggc gctcaccgtg caccgggtcg
    29581 acccggacgg ctgggcggtg ctttcccacg gcggtgcccg catcgccacc tgggtgacga
    29641 ccgtcaacga ccggaccgat cccgtcgtct tcgcggtgct ccagggagag gagagctgac
    29701 atggccgact actacgagat cctccacacg gtcggattcg aagagaccaa cctggtgggc
    29761 aacgtctact acgtgaacta cgtgcgctgg cagggccggt gccgcgagat gttcctgaag
    29821 gagaaggcgc ccgcggtgct cgaagaggtc cgccacgacc tcaagctgtt cacgctcaag
    29881 gtggactgcg agttctacgc ggagatcacc gcgttcgacg agctgtccat ccggctgcgg
    29941 ctggaggagc tgacccagac ccagatccag ttcaccttcg actacgtcca cctcaccgcg
    30001 gaaggcgagc ggctggtggc ccgcggacgg cagcggatcg cgtgcatgcg cggcccgaac
    30061 acggccacgg tgcccagccg ggtgcccgaa cagctgcgtg aggcgctggc cccgtacgcg
    30121 gtcgacggca agggggaatg acgtgggcac gctggaggaa ccctcgcggc cggtgctgaa
    30181 acggctgccg gcacccgtcg cccggcgccg gttgtccgcg caggccggcc tgcgggaggt
    30241 gatgggccag ttcgccaccg gcgtcaccgt gctgaccgcc ggcggcgaac gggcacacgg
    30301 gatgaccgcc aacgccgtca cctccgtgtc gctggagccg ccgatggtgc tgtgctgcgt
    30361 ttcccgcgcg gcccggatgc acgaggcgat cgtgacggcg ggctcgtacg cggtcacggt
    30421 gctggcgtcg gaccagaagg acctggcgaa gtacttcgcg gactggcgcc gcccggccgg
    30481 gatcgcgcag ttcgactcgg tggactggac ggccgggccg cagaccggcg ccccgctgct
    30541 cgacggggcg ctggcgtggc tggaatgcga gctggcggag gtctacgaag gcggtgacca
    30601 ctcgatcttc ctcggcaagg tggtcgcctc ctgccgcggc accgcgcagg actcgctcgt
    30661 cttctacagc ggcggctacc accagatcga cggccgcatc cgggcatccg cctgacaggg
    30721 agaggaaatg tcatgaccac caacgaatcc gccacgcccg ctccggcgcc caccgccgaa
    30781 cggccgccgg tggtgaccac gatgccccgc ctcggacggg gggtgtgctg gcgcgacatc
    30841 gtgcgcgaga tcgaactcga cgagctcgag cgcgaggccc gtatgaggga ggcggcgtga
    30901 ccctgcaggg cgatccgggc gcccagcgca cggaggactc cgaggtggtg ccgctgccgg
    30961 aagaccggct gcggcgctcc cggatcccga ggccgaccga cgggcgggtg atcccgctcg
    31021 cccgcggtgc ggagccggtg catccaccgg aaccgacgat gccgctgctg cgcacccagc
    31081 gcgacgaact gcgcgagcac atcgtcgacg gacggctcga cggcgtccgc cgccagcact
    31141 cgctcggcaa gcacaccgcg cgcgaacggc tggatctgtt gctggacccc gattccttca
    31201 ccgaggtcga gctgtaccgg cggcatcagg cgagcgggct cgggctggcg gagaaccggc
    31261 cgtacaccga cggcgtgatc gccggctcgg gcaccatcga cggacggcgc gtgttcgtat
    31321 acgcgcagga cttcaccgtc ttcggcggtt cgctcggcga ggcgcacgcg gcgaagatcc
    31381 agaaggtgat ggatctggcg atcgccaccg gctcgccgct gatcgggctc aacgacagcg
    31441 ggggagcgcg gatccaggaa ggggtcatgg cgctcaacgg ctacggcggc atcttccgcc
    31501 gccaggtcga ggcgtccggt gtcatcccgc agatcagcgt ggtgctgggg ccgtgcgcgg
    31561 gcggggcggc gtactcgccc gccctcgcgg atttcgtctt catggtgcgc gacaccgccc
    31621 gcatgtacct gaccgggccg gacgtcgtcg agaccgtgac cggggaacgg gtcagccacg
    31681 acgaactggg cggcgcggac gtgcacggcg cgtcgtccgg cgtggcgacc gtggtgcacg
    31741 acgacgagga gacctgcctc gccgacgtgc ggtacctggt gtcgctgctc ccgtcgaact
    31801 acctggaccc cgcgccccgt gagccgtcgc aggacgcggg caaggaccgg cggccgcggt
    31861 tcgccgaact cgtcccggtg gagccgaaca agccctacga catgcgtgac gtgttctcgg
    31921 aactggccga cgacggcgag ttcttcgagc tgcacgagcg atgggcgcag aacgtgctgt
    31981 gcgcgctcgc gcggatcgac gggcgcgtgg tcggcctggt cggcaaccag ccggtggtgt
    32041 tcgccggcgt gctcgacggc ccggcttcgc agaaggcggc gcgattcgtc cggttctgcg
    32101 acgcgttcag catcccgctg gtgacccttg tggacgttcc gggcttcctg ccgggcgtcg
    32161 aacaggagca ttccgggatc atccggcacg gcgcgcagct gctgcacgcc tactgcgagg
    32221 cgaccgtgcc gcgtgtgcag gtcatcctgc gcaaggcgta cggcggcgcg tacatcgtga
    32281 tggactcgcg gtccatcggg accgacctct cgctggcgtg gccgaccaac cagatcgccg
    32341 tgatgggtgc cgagggcgcg gtgaacgtgt tgttccgcaa ggatctcgcc gtcgcgcccg
    32401 atccggacgc cctgcgtgcc cacctggtgg ccgagtacac cgaggagttc atgaacccgc
    32461 agtactcggc cgaacgcggc ctggtcgacg acatcatcga cccggcggac acccggtccg
    32521 ccgtcgccag agcgctggac atgctgcagg acaagcgaaa ggcggcgcct cagcgcaagc
    32581 acggcaacca cccgatctga acgggggaac catgtcaccg tccggaatgg acagtgcgcc
    32641 ggtcttccgg gtcctgcggg gggacccgga agacgccgac ctcgcggcgc tcgtcgccgt
    32701 cttcaccgcg ctggcttcgg ccgcgccccc gcccgcggcg ccggcccggt cggcctggtc
    32761 gccgctcgtc gcgccgacct ggcgcacctc cgcgctgcgc tgagccgcgc gcgaaaacgg
    32821 cctcgctgcg cgttccgtgc tgtcgtgcgt gggctgaagg ctcccttcgt cgcgtctgat
    32881 gcggcgacgg gagccttcgc ccgttggcta ccggcgtggg attgctgtcc tcacgcgagc
    32941 cggcgcgcgg cctcggtctc ccgccgcggc ggatacgtac tgtggcgggt gtgcacggcg
    33001 acgtagagga tcccgccgtc gaccaccgtc tccagctccg tccgctcccc gggctcgaac
    33061 gcgcccccgc aggccgcgca ggtccgttgc cgctccgccg cgctcattgc cggtcccgct
    33121 gctcggggac cgcggggtcg ggccacgaca ggccgagcag gtcgacgtcg agctcgtctt
    33181 cggcgtagat ctcatacggg tcgagacgtt cggtcatggc gcgctccttg ggtttcgggg
    33241 taccacaagg gcactaccgg caccccacca ccggcgactt ttcctttgct caccgcgcgc
    33301 gcccggcatc ctcgatcgcg tcacgaccgg ctcccgatcg gacggggtca tccttggttg
    33361 tcaagtgagt cgttcatcga aggccgggag gaacgccatg acggcacagg tgcgaatttg
    33421 ggtcgtgacc gatgatctcg acccgcgcgg ggccgtcgag gccgacgtga cggcgttcgt
    33481 cccggagccg aggcaggccg ccgaaaacga tttcccggcc gagcacatcg tcctcggcta
    33541 caactagctc acccctgtac ggacagcacg gacgaagaag accgccggat atcgcgcgcg
    33601 cgagaatgaa gatcgcccgc gaaccggcca gatcacgagg aggcctccgg atggctatgc
    33661 gcctccagct cacgtcgggt ttgcaggtgc tggaagaatg ggcgatcaat gctccgcagg
    33721 ccgaccgcaa tgttatctac gaagcgcttt tcgcggtagc cgacggatcc gcttttctca
    33781 tctacgacat tttcggagat ggccgcgatc cgcaccagtt catcattctg gtgaaacatg
    33841 atctcgtcat caggataggg ctcaaacgaa ccgattcttc gttcgagatc gtctacatcg
    33901 gcgcgctgga gcacggcaca cccgccgcgg catgggccga cgacgtcgac ggctcctgag
    33961 ccggtaccgc tgaacggccc agtccgcgca tcggtaccgg cagcctttcg taccagtgga
    34021 tcatgtgttc ctcaccttga catcgtccag ttcggcgtga aattctgcga gtgtttgcgg
    34081 atggggaaat tctgccggtc tggaattgcg gttgtcgagg tctggaggca tgaaagatgt
    34141 catctcctga attcccggga ttggatgttt ccacacgggt gcgcgcacgt gacattcaga
    34201 tggcgggcgt cgccgacgtc cgccggaggg tgctgatgat ctccggcgcg atcgacacca
    34261 ccgagcacga catctcggtc agcgtcaatc tccccgaacc cggccgctgg caggtgatca
    34321 agtccgagac caacctgacc gacaagacct gggtcgcgat gcaggtcgtc accgacgagg
    34381 actcgacttt cgtcaacgac gccgacaccc tcgtgctttc ccgccagttc tcgaaatcct
    34441 tcatgacgcc ggatcagcgc cgtctcacct tctacgacgg tgaggtccgg cccggcgagg
    34501 ccgtgctgaa ggtgtactcg ctcgacgccg gcgggcggaa gccgacctat tcctattccc
    34561 gctacagccc gatcgccacc gacaccgccg agcagtccca gcagaccctg gacgaactga
    34621 tcagcaacgg gatgaagcag cgccccgtga tcgagctgat cgtcccggtg accgtgatcg
    34681 gctgagcacg ccggtgatca ccttcgtccc ggaaccgcat ctgctcgaat cgccgcgcgg
    34741 gcgggaatgg ccggttctcc ccggttcccg tgcggcgatg acccccgagc cgccgtccgc
    34801 cgccgacgtc gtcatcgtcg gggcgggccc ggccgggctc gccgtcgcct ccgccctgtg
    34861 gcaccacggc gtccgcgacc tcgtcctcat cgaccgcgac ggccgcccct gcggccggtt
    34921 cttcgaccgc gtcgacctgc tcggccagcg cgtgctgcgg tcgccgtacg aacaccaccc
    34981 cggcgtcgag ggctaccgcg actgcgaact gctggacttc gcgcggctgc actggtcggt
    35041 gctgaccccg gtggagcgcc gggagatccg catggcgcag gccggacatc gctcggtcgt
    35101 cccggtcgac gtcttcgagg cctactgccg ccatctggcc gcgagccacc acgtcaccga
    35161 acggacctgg cgcggttcgg tgcgcgaggt gctgccgacc tccgacgcgg tcaccgtgcg
    35221 cgccgaccgg ttctccgtca ccgcgcgcca cgtcgtgctc tgcctcggcg aggagcgccg
    35281 gtccgccccg gacacctggt ggggtggcgg ccatccgccg cgcggagtga cctattggga
    35341 cgaacccgtg cccggcggcg ggaagcgcct cgccgtcgtc ggcgccggac tcaccgccgc
    35401 gcacctgatc tccaacgggc tcgcccaggg gcgcgaggtg cactgggtgg tccgtgaagc
    35461 gggcgaacgc taccagtgcg ccgacgtcaa ctcgtcgttc ttccggcccg aaggccgtgc
    35521 ccgcttcgac ggggtgagct gggcggagcg gctcgaactg atgggccggt tccggcgcgc
    35581 gtcgatcatg ttcgagttcc ggccgatgct cgaggcggcc gaagccgaag ggcggctgat
    35641 cgtgcatcgc ggcaaggcga tcacgaaggt gacgccgggc gtcgggctcc acctcgaaga
    35701 cggttcgcgg gtttccgcgg accacgccgt actggcgctc ggcaccacgc cgtcgatcgg
    35761 cgacggcctg atgcccgacg aggcggtgct cgatcgcggc ggctggccgc ggctggacga
    35821 gcgcaccttc gcctacaccg gcgcgccccg ggtcttcgcg gtcggcgcgg cagcggggat
    35881 ggcgctgggc ccggccgccc gcaacatcga cggccaccgg gtcgccaccg cccgggtcgc
    35941 ggcggccgtc gccgagaacc tgcgccggga caccccgctg cggacggcca cgaaggacgt
    36001 cgcccgtgtc tgagccctac gactcccggt tcaccctgcc gtcgatcgac gacgcgccct
    36061 cgaccgagtc gggggtgatc ctgctgggcc tggacgccga acgcctgctc gccggggtcg
    36121 ggctggcccg gctcgccgac gagcccgcgc tggtggccct cgccgtggac caggcccggc
    36181 acgaggcgct cgacctcggc ctcggcgcgc tcgtcgaggc cggaatcgtt cgctggcgcg
    36241 cggtccgccc gttgatcgaa gcaggtccgg agatgacggc ggcgggttcc ctgcgccgag
    36301 aatgggaaca cgccaccgcg cgggtcaccg ccacggtgac cgggctgggg ccggcatcgg
    36361 tggcgtgcct cgcggcctgc tggctgcgtc gcgacgacgt cgatgagttc gccgcgcacg
    36421 ggcgggcgcc ggaaaagggg agcggtacac aggatgtcct atctcgggtc tttgccgact
    36481 gacgccacac tgctgcaggt cttccagaaa ttccccgcgc ccgcgtcgaa actgctggag
    36541 ctccacgaac tcctcatgcg ggcgccgtcg gccttcggcg cgggggagcg ggagctgatc
    36601 gcggcctacg tctccggcgt caacgattgt cggtactgcc acggggtcca caccgtcacc
    36661 gcggaggctt tcggtgtgcc ggaaggactt ctggccgccg cgctggccga tctcgactct
    36721 tcgcccgtgg acgaccggat gaagcccgtg ctggcctacg tgggcaagct gacgcgtact
    36781 ccggcacgga tgaccgacgc ggacgccgaa gcggtgtacg cggcgggctg ggacgaaact
    36841 gcgctgcacg acgccgtcct cgtgtgcgcc ctgttcaact tcatgaaccg gatggtcgag
    36901 gggctcggga tccgcgccga cgccgcctac gcgaagattt cgggcgtgcg gttgaaggaa
    36961 ggcggctacg ccggcctcgc gacgttgctc gacgaggcat cccgctgact gggccattcg
    37021 agtgcgggta accgggtgtc ggtcacgggg ggtcaccatg tcaccccgag atcgcactgc
    37081 cactttccgt tgtcgaaacc ggtgcctgtt actccgttcg atggccatga tcgcggaaac
    37141 ggagcagatg aaaggcacct tccggcgtag gtgaaaagca catccccgcg atgatgcatg
    37201 gcactggccg cgtacccgcc ctgagcagca cgatttcctc atcgaaggaa caccaccgaa
    37261 cagcctggga gccatcgatg atgaacaccg cgaccgacaa cgtccgctcg ctcttcgccg
    37321 tccgggggat cgacaccggg ttcgccggga atgaggtcga gctggtgatc gaccggttcg
    37381 accactggac caaccagcac cgcagtgagg cattcagctg tttcaccggc gcctgttgca
    37441 ccgccccgcc gctggccgaa gcgagctgaa cgcactttcc ggccgtcact cgctccccga
    37501 aggcgagtgg cggccggtgt cgtatgcggg gtgtctcccg ccaggacgac ggaaagtagc
    37561 cgaccgactg cggattccgt cggcaggtga ccctttcgcg ctgtcgcctc cgagacggcc
    37621 ccggccgact caccacccga acggtggaac gcgttccgtg cgggcgtgtt tatgttgggg
    37681 gccatggggg tgtgcgtgag gggacggcgc catggtgatc agagttctcg tggccgaaga
    37741 catgcacatc gtccgcgggg cgctcgtggc gctgctgcgg ctggaaccgg atatcgaagt
    37801 ggtgtccgaa gtggcgtcgg gtgacgagat cctccccgcc gcacgggact cccgcaccca
    37861 ggtcgcgatc atcgacatcg acctccccgg caaggacggg ctcaccgcgg ccaccgaact
    37921 ccacgagcag ctcccggagg tcaggaccct gatcctgacc agcctcggca ggcccggcac
    37981 gctccgccgg gcactggcgg ccaaagtgag cggcttcctg ctgaaggacg cccccgcgga
    38041 gaagctcgcc aacgccgtgc gcggggtggc ggccggacgg cggatggtcg acggcgatct
    38101 ggccctcgcc gcctgggaca ccgtggaatg cccgctgacg ccgcgggaga tcgacgtcct
    38161 gcggctgacc gccgaaggcc gcgacaccct ggaggtcgcg gcgaaggcct ttctctccac
    38221 cggaaccgtg cgcaactacc tgaccacgat cgtgtcgaag ctcaacgcgc gcaaccgggt
    38281 cgacgcgatc cggatcgcga aagagtccgg ctggatctag acgggcacaa cggcacgcaa
    38341 ccggaaccgc ccgtcgggct ccacaccggc ggtcagctcc ccgccgagcc cggcgacgcg
    38401 gtcggacatg ttcgtgatgc cgctgcccgg agcctccacc cgcaccggct gctccggctt
    38461 cggcggccgc ccgttcacca cgccgtcgtt gacgatgtcg agcgcgacgc cgtcgccggt
    38521 ccgccgcacg gcgatctcgc agcgttcgac cttgctgtgc cgcaacacgt tcgtcacgcc
    38581 ctcgcgcagc accacggcca gcacggtccg caccgtcgtc ggcaggtcct cgtgctcgat
    38641 ctccagccgc acctggacgt cggcggccac cagcaccgcc tgcgccgacc gcgactcctg
    38701 atccagcgac agttcgcggt agccgctcgc caccgaccgg acgtcggtca gcgcctgccg
    38761 cgtcagcccg aggatctcca gcagctcggc ggaggcgcga tcggtgtcga tgtccatgat
    38821 ccgggtggtc agctcgctct tcagcgcgat cgccgacagg ctcatcccca gcaggtcgtg
    38881 caggtcgcgg gcgaaccgca gccgctcctc cgcgaccgcg acctcggcga ggcgtttcct
    38941 ggtctcgccc agttcggtca ccagccggat cagccagatc agcccgaaca ccatcagccc
    39001 ggtgttcagg atggacgcga aagtgtagaa gccgccgagg aagtcggtgc cgtaggcgat
    39061 ccggatcagc accaccccgg cggcggtcac cgcgaacgcc gtccagcccg ccagcggcgg
    39121 cagcaccagc agcgcggtgc cggcgaacag gctgggcagg ctcacccacg cgctcccgag
    39181 cgggatcagc ggcaggaaga tcaggcaggc ctgcacgaac agcagcgcgt agctctgccg
    39241 cgagcgcaac cggacgttcg ggcgggcgaa gtaggacagc tgcagtgtgg tcagcgcggt
    39301 gaggtagccg gcgatgagcg ccagggacca gccgtcgtcg gtcagcatga acgcccgtgc
    39361 catcgcggag aggctgaaga cgatgaagac caccgtcatc gtccactgga cgttcctggc
    39421 gtcgatccgt gaccagtgcc cggaaccctc ggccagcgcc gtctcggtgg gctcggcctg
    39481 ttcgggcacc gggagttcgg cgtgcagccg ccaccggccc gccgcgtcgg ggcccgcgct
    39541 cagcttcccg ccgtgcccgg cgacctcccc ggtcacctcg cgcaggctct cggccgtctc
    39601 ctcgggcacg tcgtcgtgcg ccgtcccgtc gtggacgatc tccagcgcga cccggccgcc
    39661 gctctcgcgc acggtgatct cgcagtgctc gacgccggtg tagcggagca cgttcgtgac
    39721 accctcgcgg agcaccttcg ccagcagggt gcgcagcttc accgggaggt cgacctgttc
    39781 gaggtcgacc cgcaccgcga cgttcgacgc cgagagcagg gacaccgcgg tccgtgattc
    39841 cttgtcgagc gaaagctccc ggtaacccct ggccaccgac cgcacgtcgg acagcgtccg
    39901 ctgcgcgatc ccggtgatct cggcgagctc ctcacgcgcc cggtccagcg acttccgcag
    39961 cagccggtgc accagttcgc ccttgagcgc gatcgcggac aggctgaggc cgagcaggtc
    40021 gtgcaggtcc ctcgcgaagg ccagccgctg ttcggccacg gcccgcctcg ccagctcggt
    40081 cctggcctgg tgcagttcgg tcaccagccg cgcgagccag gtcagcaggt acacgaccag
    40141 ggcgtagagg accgcggtga cgctgtcgaa caccgcgccg agccaggtct cgtcgtaggt
    40201 ccacaggatc cagatcgtgc cggccatgaa cacggtgaac accgtccagc ccgtccgcgg
    40261 ccggaacagc agcagcgcgc tgcccgccgc gagggtggtc agcgagctca gcgccgcgtc
    40321 gaagtgcagg gtcggcagga acgccaggca cgcctgcacc gccagcatgg ccttcgcgag
    40381 cctggtgtcg agccggaccg ccggacggct gaagtacagc agctggatcg ccagcacggg
    40441 cccgacgtag agcacggcca gcaggccctg ccagaagtcc acccccggcc ggaacaagac
    40501 cgcgaggaga ccgaacaggc aggagttgac gaagacgacg gtgatgatca ggcccgcgag
    40561 gaacagtgcc cggcgcgggc gccggtcgac ccccgcggta cccagaggtt cggcggtcac
    40621 ggcgagctga tccggcacgg gcaccccagt ggtaacagaa gacgtcttga tccttgtcgt
    40681 gctgccccct tgcgacggcc ggggccgccg cacgacctcc atcgcggtgt gattcggatc
    40741 ctaacccatc ttcgttaccc cggttcccgc ttccgtggcg gggaggagga tgatcaagga
    40801 gaagttttcc cgtccgggac agggaaaatc gccatggtca cccgtgcggg tgtggggcgt
    40861 tcggaccaca ccggggatcg cggaacacgc cacgatggaa gacgtgggtt ccactttgta
    40921 cgccacgcgg ggcgggcggg caccggtggc cctaagctct gcgcatggcc aggtatttcg
    40981 acgtacatcc ggagaatccg caacggcgcg cgatcggaca ggtcgtcgac atcctgcgcg
    41041 aggacgggct catcgcgtat ccgacggact cctgtttcgc cctcggctgc cagctgggga
    41101 acaaacaggg catcgaccgc atccggagca tccgcaaact cgacgaccgc caccatttca
    41161 ccctggtgtg ccaggacttc gcccagctcg gccagttcgt gcacgtggac aacgcggtct
    41221 tccgcgcggt caaggcgtcc acaccgggca gttacacgtt catcctcccg gccaccaagg
    41281 aggtgccgcg ccggctgctg cacgccaaga agaagaccgt cggtgtgcgc atccccgacc
    41341 acgtggtcac ccaggcactg ctcggcgaac tcggcgagcc gctgctgtcg agcacgctgc
    41401 tgctgcccga ccaggaggag ccgatgaccc agggctggga catcaaggaa catctggagc
    41461 acgtggtgga cgcggtgatc gactccggcg actgcggggt cgagcccacc acggtcatcg
    41521 atttctcgtc gggcgagccg gagatcgtgc gccggggcgc gggcgacacc tcgcgcttcg
    41581 aatgacgcgt gggaccggcg tcccggtccc acgcgcccgc ggttcagtgg gtgacgagcc
    41641 cttcggcctt ggacggggcc gaggggatgt ggaacagccg cgtgaacagc tccagcatgg
    41701 ccggctcgcc cttgatggcc accgcgccgc aggtgagcgc gctcgcggcg tccatctcgc
    41761 cgttcagcag cttcagcacg accgggccgc gtggctcgat gacgaggtcg gggttcgggt
    41821 gcgggccctc cccggcggtc atggcgccgt cctcgaccac cgcgtgcacg atcatctgat
    41881 cgccgtagtg cagttcgaac gcgcagtcga tgccgcgggc cgcgtcgggc tggaacgtgg
    41941 tgtagagcga caggatggcc gcgtcgaggg tgaacaggtc gtcggcggcg gggtcggtga
    42001 gcgaacgggc gccccacagg cccagctgca gcaggatctg gtcgaggtcg ttgccgtatt
    42061 cggtcagctc gtagaccacc ccggcgtcga gctgcgagag cacccggcgc tgcacgacgc
    42121 cgtgccgctc gagttcgttg agccgggtcg acaggatgct cgtcgggatc ttcggcaggc
    42181 cgtgctggag ctcgtcgaag cgcttcggcc cgagcacgag gtcgcggatc acgagcaggg
    42241 accagcgttc cccgatgatc tcgagcgcgc gggcgaggcc gcagaactgg ccataggtac
    42301 gagcggtcat gcttgactcc tcagtttcct tgatctggtg gtggcgggtg gtgcttcagc
    42361 ggaccggatg tccctcggag agcagctcgc ggtgcagctc tcgcagttcg gcgcagggtg
    42421 tcacccccag ttcgtcctcg agcctggatc gcagccactc gtaggacgcc agcgcgtcgc
    42481 tgcgccgtcc gctgagcccc agcgctcgga tcaggtgggc gtgcagggtt tcgtcgaacg
    42541 ggtcggcggt ggtcagcgac cgcagcacgc cgagcatctc ccggtgcctg cccgaccgga
    42601 tctcggcctc gatccacagg tcgcgggcgt tgcgccgatg ctccagcaga tagacggtgt
    42661 aggcggccaa ggtcggtcca cagtggatgt tcgccagcgg gggaccggac cacaggtcca
    42721 gcgcggtacg gaacgcgtgc gcggccgccg cgttgtcacc ctcgtccagc aggtcgctgc
    42781 cgagccggtg gagccgctgg aactccgaca cgtcgaccac gcccgcgtcg atctcgagcc
    42841 ggtagccggg cgagctggtg accagcaggc cgccgttgcc gccggggtcg aggtggcggc
    42901 ggaggtggtg gacgtaggtg tgcagggtcc ggcggacact gcgcgggggc gcgtcgttcc
    42961 acagctcgtg gacgagggag tcgacgtgga ccgtcttgcc gggacggatg agcagcatcg
    43021 ccagcagttg caggagtttc ggcgtgctcg gcgcgcggtc ggcgccgccg atgtgcagct
    43081 cgagtggccc cagcagcctg gccgtgtcac ccgcttcgat ggtcatcgcg tgcatccctg
    43141 cccctccggc ggagtccccc tcgatgacgg tgacagaggc ggaaccttcg gaacagtgcc
    43201 ggaaacaccc ggcaggccat gatttcttcg ttgcgcggta tgcgatcgtc acgacctgga
    43261 gcgatgaacc ggttgtggca aaagagaaga cgcggaacgg gtcagagcca gtccgaatcg
    43321 gtggcgatac ggatggcgtc caccctgttg cgggcgttga gtttcgtgac cacggtggcg
    43381 agatagttcc gcacggttcc cggcgacagg aacagttccg ccgcgatgtc ggcgaccgtg
    43441 cgcccgttcg cggcgaggcg gaggatctcc gcttcccgcg gggtcagcgg gcagtcctcc
    43501 gtttcccagg cggacaacgc gagttcgctg tcgatgaccc ggcggccgat ggcgaccgac
    43561 cggacggcgt tggcgagctt gtcggccggc gcatccttga gcaggaagcc gttgaccttc
    43621 gcgtcgagcg cgcggcgcac ggtgcccggg cggccgagcg aggtgaggat cagcgtgcgg
    43681 acgctcggaa gttgctggca gagctcggaa gcggccgcga gcccgtcctt ggccggtaga
    43741 tcgatgtcga tgatcgcgac gtccgggaga tactccgcgg ccatcgggag gatcttgtcg
    43801 ccggagctga cctcggcgac gacctcgatg tcctgttcga ggttcagcag agcgaccaag
    43861 gcgccacgga ccatgtgcat atcctcggcc aataggactc ggatcactcc gacctcctct
    43921 tccccagaaa cgcgctaact ctcagtgtac atagcaaacc cggaagagtg aatcggaatc
    43981 gcacgatgca aggttgcgct tttccttggg gtctgcccga cgtgatcaat gtgctggtga
    44041 gctgcggcga tgcgtcggct tcgagagtac tgaaactgcg agcgatcgat tactggctgt
    44101 caggtcagaa gaaggtaaaa ttgctacctc gagtggtttt cattccccgt cgagtacgtt
    44161 ccattccggt gaatcagtcc ggcgaacggg tgaactctct ccattccgga gagggcgatg
    44221 gactgttcgg cggtaccggc gccggcctcg atcggacgtc gatcgcggca tggtctcctc
    44281 ggcacgagcc ggttcgcgcg atgccgccac tatccacaaa ggacgtatga tgagctcatt
    44341 gctgggtgcc ctgcgcaagg tcatgttcgc gccttcgctg gcttcggtcg gcttcgaggg
    44401 gcgcggcttc ggagtgccgc ggacgccgtc gaccgcgcgg ctggagtcga tcccgcagtc
    44461 ggtggtgtgc ggcttcgagt gggggatcga cgcgccggcg ctgtgggagg ccgaacggcg
    44521 gctggacatg gtcgagccgg agatgcgcgg gttcgcctac gagggcgcgg cgatggcgtt
    44581 caccatcctc gacgtcatgc ccggcggccg caaggaccgc acggccgaac tgatgagcgg
    44641 ccccggcctc ccgcacgtgt tcctgaccta catcggcatc gggttcgcga tggcccggct
    44701 gccccggccg ctgtggaaga aggtgctgcc ggagctggac ggcgtgccgt tccacccgac
    44761 gatgagctgg ctggccgtcg acggctacgc gttcgaccgc gcctacttcg acacgcgcaa
    44821 gtgggtcgac gagcagttcg tccccaagca gtacccgtgg gcaggggccc ccgcgtactt
    44881 cccgcgcgcc tgcgatcagg gcatcggccg ggcgctgtgg ttcatcaacg gcggcgatcc
    44941 ggtgaaggtc gccgcggcgg tggaccgctt cccggccgga cgccgtccgg acctctggag
    45001 cggggtcggg ctggcttcga ccttcgcggg cggctgcgac cggccagggc tggtgaggct
    45061 tcgcgaggcg gcgggggagc accaggacga gctcgggctc ggcgtggtct tcgcggtgaa
    45121 ggcgaggacg ttctcgtcgt tcgtcccgcc gcacacccgc cgtgccgccc gcgcgctcgc
    45181 cggactgagc gtcgaggagg ccgtcgagct ggccgactcg accgaggtca ccgaggacgc
    45241 cgccgatggg acacccgcgt acgagctgtg gcggcagaac atccgggagg gtctggcccc
    45301 gtcggcgggc cggctctccg cctgagggtc cgtggatgtc atgaaagggt cgttcaagac
    45361 gttttccgtc ctgaacgacc ctttcatgac atccgggtga gggtcaggcc gcgcgctgga
    45421 acggctccgg ccggtgccgc agatcgggca gcgcgagcag gaccggcggg tcgaacaggc
    45481 gcttgggacg catccgcagg tccgcgagcc gcgcggtgac ccccggctcg acggtgatcg
    45541 gaccgtggtg cccggtgtac ccggtaccgc ggcgcgtgag cgggccggtc acgcagtgcg
    45601 cgacgaggtg ccagtcgccc tccgggacct cggtcagctg ataggggccg ggggcgtcga
    45661 tgaccgtgta ccgcacgggc gcgccctcgg ggatccgcgt cgggaagagg ccgacgaaga
    45721 cgaggccggg cgagatctcc ggcggcgccg acacgaaacc gcggacgatc gcccgcttcg
    45781 ggccgggacg gggctcgcct gccaggcggc gctggaagcc gccctgccgc cggtacgcgg
    45841 acggggacag gccgacgcgg ctgctgaacc gcgtgctgaa ggtgccgacg ctgttgtagc
    45901 ccacgcggtg gctgatgtcg gcgaccgtga tcgaggtggt cagcagcagg cgcttggcct
    45961 cgtcgagccg cagcgcggag aggaaccggc cgggcgagac cccggtggcc tgctggaaca
    46021 ccctggtgaa atggaatttg ctgaaggtcg cggcgcgggc gatgtcgtcg atagtgagct
    46081 cttcgcccag tttctcgttc atggccccaa tggctcgctc cacggctcgc cggacagtct
    46141 catccattgt gccgtccttt cgctcgagga tttctggcat gctttgcggt ttccgacagt
    46201 agtgttcgcc acggcttctc ctgaagtgct tgattcaccg ccggatatgg attcctgtgt
    46261 gcgccgacgt gaaaatttca cggggtgggc gagcatgcga aaaccatgcc ccacgggtgg
    46321 tgcgcgcact ggatcccggt ggccggtggc cgcagaattc ctggtagcgc attcacgccg
    46381 gaacctcccc ggccgtgttg gcgcggtccg aagaacgtat tcccgcggca acacagaacc
    46441 ggcccttgac cgcgtccccc gcggcggtca agggccggtt tccatttcgc ggaacgagtg
    46501 tgtgacgata gtatcgtcgg ctcgtggggc gagacgcagg cgaaaggcag atggggtcga
    46561 tgatcaaggt cctggtggcc gaggacatgc acattgtccg gggggccctg gtcgcgctgc
    46621 tcggattgga acccgacatc gaagtcgtcg ccgaatgcgc cagcggcgac gagatcctcc
    46681 cgctcgccca gtccgcgcgc cccgacatcg cgctgatcga catcgacctc ccgggcaagg
    46741 acgggctcac cgcggccgcc gaactgcacg agcaactgcc cggtgtgcgc acgctgatcc
    46801 tcacctcgct cggcagcccc ggcaccctgc ggcgggcgct ggccgcgaag gtcaacggtt
    46861 tcctgcgcaa ggacgcgccc gccgaccggc tcgccaacgc ggtccgcggg gtcgccgccg
    46921 gacggcgcgt cgtcgacggc gacctggcgc tcgccgcctg ggacagcgag gaatgcccgc
    46981 tcaccgcccg cgagatcgag gtgctccggc tggcgtcggt cggctccgat ccgaccgaga
    47041 tcgccgccga gttgttcctg tccgcgggca ccgtgcggaa ctacctgacg acgatcgttt
    47101 cgaagctcag cgcccgcaac cgggtcgacg ccgtacggat cgcgcgcgag tccggctggc
    47161 tgtgacgccg gcccgcctaa cgggcgggga cgttcatcgt cgcgtgggcg agatccgcgg
    47221 cgaactcgcc gggagaagcc gcttccgcga gcaaccggcg ctgccgggcc gcgccggtgc
    47281 cgtgttcgaa cagtgagtcc aacccccggt cgacgtcttc ggcgtcgccc gcagcggtga
    47341 gcgccggccg gatgaactcg acgagttcgc cgagtaattc ccgctgatcg gcctcccggc
    47401 cggtgaagac gtcgacgccc ggcccgtcga gaccgcggcg cgcggcggcc gccaaggcgg
    47461 cgtcgatccg ggcgccgcgg gcgcgtggcg gtctcgtcgt cgcggcgcag gtcgcgacca
    47521 gcccgcgcac cagcgccgcg aggagcacgg cgtcgtcgac ggccaggcag acgtcggcga
    47581 tccgcacctc gaccgtggga tgccgagggg aaaggcgcgc gtagaagtac acgcccgccg
    47641 cgtcgagcgc ggcgccgcgg cgcaaggcct cccggatgct ccggtcgtac gcggccgcgc
    47701 cggaccattc ctcgggtggc ttcgccgtcg gccaccggtt ccagatcggg aaacgccggc
    47761 tcgcccagcc ggaatcggca gcgttctcca ccggggagtt gacgctgagc gccagcaacg
    47821 gcgcgagcca cggccgcagc ccggcgagga cgcgggcgcc gaggtcccgc gacggcaggc
    47881 cgacatgcac atgacaggca cacgtccccg cctcgccgat caggtccggg aacgcctgcg
    47941 ccatccgccg gtagcggggt tcgggcgtga gcgtgtctcc ccgcaggccg gcgggcggga
    48001 tccccgccgc caccatcagg caaccgtcgg cttccgccgc cgtcgcgacc atctgccgca
    48061 gccgcgtcag ctccgaacgc acctcgtcca gaccgcggca gacaccggtc gcggtctcga
    48121 tctggaaccg catcagctca ccggtgacgt cggtcccggg ggcgaggctt tcgagaagct
    48181 cgggcgcgcg caacgcgacc gagccgtcga ccgggtcgag caggacgaac tcttcttcca
    48241 ccccaacggt gtaggtcatg ccgtcgaccg ccatggttcc ccgttcgtgg tttcgccggt
    48301 gaacctccga atctgcccct tcgggcgcgg cgaggaaagg gccggtgtgc tgaacttcgt
    48361 tgcggcgaaa gtgtttcgag gcctcactga cggtctagtc tgcgttcatg atcgatctgt
    48421 acccacctgc cgagccgtac gacaagggac tgctcgatgt aggtgacggc aacctcgtct
    48481 actgggagac ctgcgggaac cccgccggga agcccgcggt catgctgcac ggcggccccg
    48541 ggcagggctg tacgccggga atgcggcgga tgttcgaccc ggcccgttat cgcgcggtgc
    48601 tgttcgatca gcgcggctgc ggccgcagca ccccgcacgc gagcgacccg gccaccgaca
    48661 tgcggcacaa caagacggat catctcgtcg ccgacatgga acgtctgcgg gaacacctgg
    48721 ggatcgaacg ctggctcgtc accggcggtt cgtggggcac caccctcgcg ctcgcctacg
    48781 ccgaacgatt cccggagcgg gtcaccgaga tcgtcgtcag cgccatcagc acgacaaggc
    48841 cctccgagat cgactggctg tatcacggcg ccggccggtt cttccccgag gaatgggacc
    48901 gttttcgcgg tgatctctcc ggtgacctgg tcgccgccta cgcgcggctc ctggaagatc
    48961 ccgacccacg ggtgcgaatc gaggccgccc gttcctggtg ccgctgggag gacaccgtgc
    49021 ttttactcga acccgacgcc accgtccaca atggtccgat cggcgaatgg gaactcgcgc
    49081 tcgcgcgcat cgtcacgcac tactactccc acgccggctg gctggagccc ggcgcgctga
    49141 tccgcgatgc cggcctgttg cgtgacattc ccggagtgct gatccacggc cgccgtgacc
    49201 tgagctgccc ggtggacacg gcctgggaac tcgcccgcgc ctggcccggc gcggagttgc
    49261 tgatcgacga cgattcagga caccattcga gcgacgtgaa gcgggcctgg aagctcgcgg
    49321 cgctggaccg gttcgcttct tcttaagcga gcagacgatc tctcacctgg cttagttgag
    49381 tcctggtagc tcctcccttc gtcaggtagt tgtatgcgcc tccgtggcgg ttctccaagt
    49441 gggccagggt acggagaatc gtgtcgccgc tgcatccttc cgtgagcgcg tagtcctcgg
    49501 cgatcgccga gggtggcacg cccgcgacac tcaacgcgag cgcgacgagc actcccgtcc
    49561 gatctcgccc ggcgctgcag tgcactgcga gcggcccggg cggagcgtcg ctcagctgaa
    49621 tgaaaacgcc ggtgatctga ggtcggttgt cgtcgagcat cgtgcggtac gcgtccggca
    49681 tggtggtgcc ttgttcggc
//
