LOCUS       NC_021252              21026 bp    DNA     circular CON 28-MAR-2024
DEFINITION  Amycolatopsis keratiniphila, complete sequence.
ACCESSION   NC_021252
VERSION     NC_021252.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis keratiniphila
  ORGANISM  Amycolatopsis keratiniphila
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
REFERENCE   1  (bases 1 to 8948591)
  AUTHORS   Tang,B., Wang,Q., Yang,M., Xie,F., Zhu,Y., Zhuo,Y., Wang,S., Gao,H.,
            Ding,X., Zhang,L., Zhao,G. and Zheng,H.
  TITLE     ContigScape: a Cytoscape plugin facilitating microbial genome gap
            closing
  JOURNAL   BMC Genomics 14, 289 (2013)
   PUBMED   23627759
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8948591)
  AUTHORS   Xu,L., Zhao,W., Ge,M. and Zhao,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAR-2012) Shanghai Laiyi Center for Biopharmaceuticals
            R&D, Shanghai 201203, China
COMMENT     ##Taxonomic-Update-Statistics-START##
            This Genome (query)               :: GCA_000400635.2
            Current Name                      :: Amycolatopsis keratiniphila
            Previous Name :: Amycolatopsis orientalis HCCB10007
            Date Updated                      :: 2018-10-26
            Analysis Type :: Average Nucleotide Identity (ANI)
            Analysis 1 (A1) :: Query vs. TYPE genome for current name
            A1 Genome (subject)               :: GCA_001620365.2
            A1 Name                           :: Amycolatopsis keratiniphila
            A1 ANI                            :: 96.94781%
            A1 Query Coverage                 :: 84.86%
            A1 Subject Coverage               :: 83.93%
            Analysis 2 (A2) :: Query vs. TYPE genome for previous name
            A2 Genome (subject)               :: GCA_000478275.1
            A2 Name :: Amycolatopsis orientalis HCCB10007
            A2 ANI                            :: 90.22668%
            A2 Query Coverage                 :: 73.73%
            A2 Subject Coverage               :: 73.08%
            ##Taxonomic-Update-Statistics-END##
            ##Assembly-Data-START##
            Assembly Method                   :: Newbler v. v2.5
            Sequencing Technology :: Sanger dideoxy sequencing; 454; Illumina
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000400635.2-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 02:04:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,307
            CDSs (total)                      :: 8,242
            Genes (coding)                    :: 8,193
            CDSs (with protein)               :: 8,193
            Genes (RNA)                       :: 65
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 33 of 49
            Pseudo Genes (internal stop)      :: 3 of 49
            Pseudo Genes (multiple problems)  :: 1 of 49
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:56:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1700938
            Orig. end                         :: 1721964
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003410.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Shanghai Laiyi Center for
            Biopharmaceuticals R&D, Shanghai 201203, P.R. China,
            hccbred@gmail.com.
            The organism was changed from 'Amycolatopsis orientalis HCCB10007'
            to 'Amycolatopsis keratiniphila' in October 2018.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21026
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21026
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21026
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11026](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11026)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    1293..1306
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.61"
                     /tool="antismash"
     gene            complement(1330..2502)
                     /locus_tag="AORI_RS49035"
                     /old_locus_tag="AORI_1606"
     CDS             complement(1330..2502)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034065.1"
                     /locus_tag="AORI_RS49035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1606"
                     /product="macrolide family glycosyltransferase"
                     /protein_id="WP_016331999.1"
                     /sec_met_domain="MGT (E-value: 5.2e-49, bitscore: 166.4,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNQHIAMIGSTAPSHIYPSLAIIRELVARGHRVSYAVGEPLTGL
                     IEPTGAEVVAHPSILPLGDQAAWPEDPASQMRVFLDEGIQAMPVLTDFYDENRPDLLLY
                     DIGGLPAPLLARRYGVPAVQLSPTYVAWEGYEEDMGEIITAIRTSPSGKDYFATFTRWL
                     NENGIEADAWDWISHPPQVLALLPKAMQPNVERVPSTVRFVGPALDPERLADRSWTPPS
                     NGRKVLLMSLGTAFTDQLDLFRACVDGFRDSDWHVVISIGQTDPASLGPLPEHIEVHRF
                     VPQLAVLEAASAFITHAGMGGSTESLWYGVPTVAIPLATDGFGNAAKLAELGVGEQLPA
                     DEVTASTLRAAVERVAGSPEVAARLAEVRAETRGNGGIDRAADAVESFLA"
     misc_feature    complement(2792..2810)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.78"
                     /tool="antismash"
     gene            2793..4349
                     /locus_tag="AORI_RS49040"
                     /old_locus_tag="AORI_1607"
     CDS             2793..4349
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (88-448). E-value:
                     4.2e-19. Score: 61.0. Matches aSDomain:
                     nrpspksdomains_AORI_RS49040_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034064.1"
                     /locus_tag="AORI_RS49040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1607"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_016332000.1"
                     /sec_met_domain="PF00561 (E-value: 5.9e-27, bitscore: 93.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVLITALAAATLASVAVTAPAGAAEAAQPVESITWGACTDPTL
                     INAGAECGYLSVPLDYSRPRGEKIQLALSRVKHKTPDAQYQGVMLTNPGGPGGSGLLLA
                     TRGTRVPNRAGDAYDWVGFDPRGVGSSKPALSCIPDYMDYNRPNYVPTTRQLEKTWLQR
                     SKSYADACAEKNSRALLENIKTTDTVKDMESIRKALRVEQLNFYGYSYGTYLGQVYGTL
                     FPQHVRRMVLDSTVDPRNVWYQANLNQDVAFDVNLNIWFGWVAQHDGVYHLGKTQAAVK
                     QVFNEQLKKVAAVPAGGFIGPDELLDVFQQASYYQLRWTLLGDALAKFVNKGDWQTMKG
                     LFEAFGGRGDDNGYAVYLAVQCTDVKWPPSWQQWKRDNWRTYEKAPYFTWQNAWFNAPC
                     LFWPAKPGKPVKVDGSKVPSVLMIGETLDAATPYEGSLEVRSRFPGARLIGEPGGTSHA
                     ITPRGNACVDNRIADYLATGALPDRKPGRTADVECAPLPLPVPPPAPASAPGTALSRVP
                     A"
     aSDomain        3057..4136
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AORI_RS49040_Abhydrolase_1.1"
                     /evalue="4.20E-19"
                     /label="AORI_RS49040_Abhydrolase_1.1"
                     /locus_tag="AORI_RS49040"
                     /protein_end="448"
                     /protein_start="88"
                     /score="61.0"
                     /tool="antismash"
                     /translation="MLTNPGGPGGSGLLLATRGTRVPNRAGDAYDWVGFDPRGVGSSKP
                     ALSCIPDYMDYNRPNYVPTTRQLEKTWLQRSKSYADACAEKNSRALLENIKTTDTVKDM
                     ESIRKALRVEQLNFYGYSYGTYLGQVYGTLFPQHVRRMVLDSTVDPRNVWYQANLNQDV
                     AFDVNLNIWFGWVAQHDGVYHLGKTQAAVKQVFNEQLKKVAAVPAGGFIGPDELLDVFQ
                     QASYYQLRWTLLGDALAKFVNKGDWQTMKGLFEAFGGRGDDNGYAVYLAVQCTDVKWPP
                     SWQQWKRDNWRTYEKAPYFTWQNAWFNAPCLFWPAKPGKPVKVDGSKVPSVLMIGETLD
                     AATPYEGSLEVRSRFPGARL"
     misc_feature    4430..4444
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.05"
                     /tool="antismash"
     misc_feature    complement(4434..4447)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.84"
                     /tool="antismash"
     misc_feature    complement(4435..4448)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.49"
                     /tool="antismash"
     misc_feature    complement(4440..4452)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            4492..5394
                     /locus_tag="AORI_RS49045"
                     /old_locus_tag="AORI_1608"
     CDS             4492..5394
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020662015.1"
                     /locus_tag="AORI_RS49045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1608"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_016332001.1"
                     /transl_table=11
                     /translation="MADAFSLEGLVKRFGDVLAVEDVSVRAAPGEVVALLGPNGAGKST
                     TIDMLLGLSRPDSGQVRVAGLSASEAMDRGMIGAMAQNGTLLRDATVAELVGLFASLHR
                     NPLPVREVLKRAGVTEYANRRCGKLSGGEQQRVRFALALVGDPDLLVLDEPTAAMDVDG
                     RRRFWASMREYTETGRTVLFATHYLAEAEDYADRVVLMRHGRVVADGPVGDVRAAVAGR
                     VLRAVVPDATQAALAALPGVSRAVLRAGHAELNCADSDAAIRGLLREFPLAANIEITAV
                     GLEEAFIALTADEAEGALR"
     gene            5391..6122
                     /locus_tag="AORI_RS49050"
                     /old_locus_tag="AORI_1609"
     CDS             5391..6122
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020634257.1"
                     /locus_tag="AORI_RS49050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1609"
                     /product="ABC transporter permease"
                     /protein_id="WP_016332002.1"
                     /transl_table=11
                     /translation="MNPAYLALEIKRIVRSPQFALFTIGMPLAMFLLFGGIFGAREIAP
                     GISTATVTMVNMAAYGAMTAALFTGTRVATERTDGWQRTLRLTPLRAPGYLMVKVAAGL
                     FVALPVLLVIFAAGMIRGIRLETGQWLTIFGTLWLGTLPFAVLGLMIGLFGKGDTVQAV
                     TGALMLPLGMFGGLWIPLQVLPGWMNTAGHLMPTYWLGEIGRAPVLGGSGLLTAAGVLA
                     AWLVVPALVVMARFRLDTARL"
     gene            6143..6772
                     /locus_tag="AORI_RS49055"
                     /old_locus_tag="AORI_1610"
     CDS             6143..6772
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020634258.1"
                     /locus_tag="AORI_RS49055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1610"
                     /product="hypothetical protein"
                     /protein_id="WP_016332003.1"
                     /transl_table=11
                     /translation="MVEDERDGDERPMTPEESLALIATQAERTRREIGPNPAVLLGVWG
                     LVWLFGFGLIYVSAPPTALMPLWVAAVLTVVGFAGAMTYSAIYGIRSSRGVHGPSRLVG
                     AMYGWSWMIAFGGLTVVNTALIRLGIDADLIPLLWSGTALMLTGLMYLAGGMLWQSKLQ
                     YGLGVWIIACGAASVLAGGPYNFLVLSVAGGGGFLVASLVFLVRAR"
     gene            6769..7092
                     /locus_tag="AORI_RS49060"
                     /old_locus_tag="AORI_1611"
     CDS             6769..7092
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153148.1"
                     /locus_tag="AORI_RS49060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1611"
                     /product="transcriptional regulator"
                     /protein_id="WP_016332004.1"
                     /transl_table=11
                     /translation="MSEDGLPQLDPVIHAQARLRVTVALSSLGPGDSITFPRLQQLLDM
                     TPGNLSTHLRKLEDAGYVGITKAFEHRTPVTLVELTTRGRAAFEEYTKALHRLLEVPGD
                     GRA"
     gene            7079..8395
                     /locus_tag="AORI_RS49065"
                     /old_locus_tag="AORI_1612"
     CDS             7079..8395
                     /EC_number="2.7.7.7"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332005.1"
                     /locus_tag="AORI_RS49065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1612"
                     /product="DNA polymerase IV"
                     /protein_id="WP_016332005.1"
                     /transl_table=11
                     /translation="MGGHDRWVIHLDMDAFYASCEQLTRPTLAHRPVLVGGAGPRGVVA
                     GASYQAREHGIKSAMPMSQARRLLPPNGVILPPRFKLYELLSTRVFDLVATYAPVLERI
                     SLDEAFAEPPSLVGASSEDVREFGARLREHIRSDIGLVASIGAASGKQVAKVASDLAKP
                     DGLLVVDQGTERDFLAPLPTRVLWGIGPVAEGKLRAIGVRTLGQLTALSDADAVSTLGS
                     VVGRDLRRLATGVDDRPVSDRAELKQVSAETTFDRDLIDLPSLRREVRDLAVHAHRRLV
                     NAGRVARTVVVKLRHTDFSTVTRSETMASPTDEFDQLAAMAERLLIDPTEFGGVRLAGV
                     ALSGLSVPHQDPLFTLSVPAPDVPVVERAPAPVPVVASSWRPGDDVVHDEFGTGWVQGA
                     GHGRVTVRFETRSSGPGVARTFTQEDPALRRGEPGDCLA"
     misc_feature    8554..8569
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 25.83"
                     /tool="antismash"
     gene            8639..9766
                     /locus_tag="AORI_RS49070"
                     /old_locus_tag="AORI_1613"
     CDS             8639..9766
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034061.1"
                     /locus_tag="AORI_RS49070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1613"
                     /product="CapA family protein"
                     /protein_id="WP_016332006.1"
                     /transl_table=11
                     /translation="MFSSRVRQATALLGAAVLLAACSGTPEQRQPPAAPPAPQASQAPD
                     GSFTVVATGDVLIHPALTEQAKEDGGGKIDYRPLLAGIKPLISGADLGICHLETPLAPK
                     GGPYSGYPSFSAPPEIVDALKDTGYDNCSTASNHTIDQGVDGATRTLDKLDEAGIKHTG
                     SARSAEEAKKPLIVDVNGVKVAQISFSYGFNGIKVPAGKPWLVNQIDAEDVIAQAKAAR
                     KAGAQVVLASLHWGTEYQHDPTAEQRTLAKKLLGDDSIDLIIGHHAHVVQPFEQINGKW
                     VAYGLGNSVARHSEPKGSTEQGAAARFRFVRDGERWKVDKAEYVPTLVQLGPPIRLLDL
                     TAGPAGNAGAEALKATDEVVLSRGAADKGLTRPGR"
     gene            complement(10001..11026)
                     /locus_tag="AORI_RS49075"
                     /old_locus_tag="AORI_1614"
     CDS             complement(10001..11026)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034060.1"
                     /locus_tag="AORI_RS49075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1614"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_016332007.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.9e-63, bitscore:
                     211.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTIETHTGARPAGEVLTWSRNLLDPALREAVDGLPESMRLIAGY
                     HFGWWDEHGRPSTSDSGKALRPALALLSAQAVGGDAEIAVPVGVAVEMVHNFSLLHDDV
                     MDSDTTRRHRPTAWTVFGTGAAILAGDALLCRAFEVLAPFGQTALRVLSTAVIDLLEGQ
                     SADLKFEERGDVDTAECVRMAEGKTGALLGASCTLGALAGEGRQDQIDRLTEYGRALGL
                     AFQHIDDLLGIWGDPAVTGKPVHSDLSNRKKSLPVVAALHSGTDAGRELDALYRKESLD
                     AAELPHAAELVDRAGGRTWSQEQADALLTGALHHLAVSNPVPRPGAELAALAKLVVRRR
                     Y"
     misc_feature    11064..11078
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.79"
                     /tool="antismash"
     gene            11481..12245
                     /locus_tag="AORI_RS49080"
                     /old_locus_tag="AORI_1615"
     CDS             11481..12245
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034059.1"
                     /locus_tag="AORI_RS49080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1615"
                     /product="DUF4239 domain-containing protein"
                     /protein_id="WP_016332008.1"
                     /transl_table=11
                     /translation="MGIYLTGIAWVVGAAALAGLVGYLVRKFGWDEGRPDNNDAAGQVF
                     TIVGGLHAVLVAFILISLFDSASAAREGSYHEADSLVAAVWAADSLGTEVKDEVRKLST
                     EYMTTVEQKEWPLMAGGETTLPDTGWTLLDRLRKAVDKAPTDDDWLRERKTEANTQLWQ
                     VYEARQERLNAVVGGRVGGVVWFALILGSLISALLPNLFGGTRLAAHLVIVSTLAGTVT
                     LLLFAIYQLQNPFGGGVRIPPDAFSAALARIS"
     gene            12268..13458
                     /locus_tag="AORI_RS49085"
                     /old_locus_tag="AORI_1616"
     CDS             12268..13458
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153129.1"
                     /locus_tag="AORI_RS49085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1616"
                     /product="hypothetical protein"
                     /protein_id="WP_043847956.1"
                     /transl_table=11
                     /translation="MTRGAATVAVAGLVGASALLAPMAARAAESCLAVQAETGSYGKSK
                     LRWLDVGSGTTSRVTEPGYRLNALGYSATRNLVFGVAEGLSRGAHAVTIDREGKTQDLG
                     PITRAGNRLPLWSPVAGVTAGAIGGNSWYLLRNGTLYTVDLTPGERYLRVIGTVFLRPI
                     TLAHDVNDFAYHNGLLYGVSTTWRGKGAVITIDPETGKVREAEDARFPPADVYGSVVLG
                     RDGALYATANRIGGRSVLYRLDRSGQVTVVLSGPPLAGSDAAGCLTAPEPPKPEPPNPE
                     PPKPEPPKPTPTPTPTSSPSPTPTSSSSPPSPSPSSSPSPTPSSSPAPRSAPQVMPQPP
                     VSAPRPSRSVAPRERKEAAEEVDPHARTKEKRRWGLTALVLILGGGAAAGAVRRAR"
     gene            complement(13460..14476)
                     /locus_tag="AORI_RS49090"
                     /old_locus_tag="AORI_1617"
     CDS             complement(13460..14476)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020634270.1"
                     /locus_tag="AORI_RS49090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1617"
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_200870964.1"
                     /transl_table=11
                     /translation="MRGPTKTLVVATVLALGMVFGLAGCDGEEPAGMAARPIRIAFVPK
                     VAGIPYFEAMNTGGQAAAKQLGVEWSSTGPATVDPAAQVSIVRGLVDQQVDVIAIAPND
                     PRAIAPAITDARAKGVHVITSDTDAPGTDRELFVNQATPEGIGKALTDALMKKMGNAGK
                     YAIVSCGETAENLNAWIAVQRAYTATAYPHAQLVETVYAGEDKDNATALAKQLMTKYPD
                     LTGLVGECTTSAPGVAEAVRSQQKIGRVFTVGVGTPQAIKPYLLDGSASLSVLWNVESL
                     GYLTAWAGKQVAEGKQPGPSNKVNLELPAIKYEEDTKTLLLGDPLLITRENVDQFKY"
     gene            14736..15164
                     /locus_tag="AORI_RS49095"
                     /old_locus_tag="AORI_1618"
     CDS             14736..15164
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034056.1"
                     /locus_tag="AORI_RS49095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1618"
                     /product="DUF4396 domain-containing protein"
                     /protein_id="WP_016332011.1"
                     /transl_table=11
                     /translation="MAVSATLHCLTGCAIGEVLGMVIGTALGFGNLATIVLAVALAFVF
                     GYALTMRGVLKSGLPFGAALKVALAADTVSIAVMEIVDNAVMLVVPGAMDAGLGSLLFW
                     GALAFSLAVAFVLTVPVNKWMIGRGLGHAKVHAHHGGH"
     gene            complement(15484..16695)
                     /locus_tag="AORI_RS49100"
                     /old_locus_tag="AORI_1619"
     CDS             complement(15484..16695)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223424.1"
                     /locus_tag="AORI_RS49100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1619"
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="WP_043848621.1"
                     /transl_table=11
                     /translation="MSVSRRTLLTTAAGAAVAATTTITPAASAAGELRTFRRTADYAVT
                     KLRAVAPGVTAFPEITRFEKWTYSQNGGWIGGFWPGTLWLASIYSGDARFRTLAMASAE
                     KLAPRQYETRDHDLGFLFYPSWVTGWRLTGDEKWRAGALNAAASLIQRYNEKGRFIRAW
                     GALGTPGNAGRVIVDTMMNLDLLTFASKQTGDRKYLDIAVSHAKTTERVFVRPDGSTPH
                     VFDFDPDTGAEIGPETVQGYSPTSCWSRGQAWGIYGFTTMYRRSGEPLFLRTAQRMADF
                     ALHALTPDNLPVWDYLAPQAPYDIKDSSAGAVMACGLLDLAKVANRPQYREAAIRILTA
                     LCDTCLTAKSTRAEAIMARGTRNRRAEDGVEVSLPYGDYYLLEGILRVLMPREIDRAID
                     LSSV"
     misc_feature    16789..16802
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.22"
                     /tool="antismash"
     gene            complement(16790..18175)
                     /locus_tag="AORI_RS49105"
                     /old_locus_tag="AORI_1620"
     CDS             complement(16790..18175)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017985982.1"
                     /locus_tag="AORI_RS49105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1620"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_016332013.1"
                     /transl_table=11
                     /translation="MNPPETTTLREKLSGTVITAADPGYDAARAVWNGDIDRRPAVVAE
                     CATREDVVTALAFGREKGLEITVRGGGHSFSGSAVADDGLVIDLGGLRRITVDPGARTA
                     VVGGGAVWADVDETTQRYGLATVGGTVSDTGVGGLTLGGGFGWLTAKHGLTIDNLLSAE
                     VVTADGRILRASEAEHPDLFWALRGGGGNFGVVTEFEFRLHRVGLAEVGLFFWTLHDAP
                     QALRFAKDVTATLPPGTGSMLVGITAPPAPFVPPEHHLAPGLALVVAGFDGPERHARIV
                     ERIRDGLPAAFELVTPMPYAELQKLLDPTAPRGILAYEKSLYVSSLSEKVIDVIAARLP
                     DKASPTTVMPIVPLQDTFSTVPDDATAFGGPRTPGFVIGLAATAPTPELLAADRAWARA
                     LWEELLPHSNNYGGYLNFMNEYDEDRVRTAFGAEKYARLAAIKAVYDPDNVFHHNANIR
                     PAE"
     gene            complement(18318..19538)
                     /locus_tag="AORI_RS49110"
                     /old_locus_tag="AORI_1621"
     CDS             complement(18318..19538)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223425.1"
                     /locus_tag="AORI_RS49110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AORI_1621"
                     /product="hypothetical protein"
                     /protein_id="WP_016332014.1"
                     /transl_table=11
                     /translation="MVRTVKARRVMAAVLAMGAVTALAASPANAAPEGSWRADLSTVDG
                     DDVNVRSDGGVLSLENAAWHRKPDSIGSQGYLLLAEQKLGKPVNRVTAQVTADAPKGTE
                     VEVDVRGKLNSQDWTEWTPADGGTQLSASVSTVQVRVGLRTVHDGVTAKVSDVTLLGEL
                     APQVNAIGAAAAPLTYKVYGTREGLVGGTTANGHVIKSRDHFVALPSGRGLAPKNTGNY
                     TVRICRTDNSRCEYAPVWDVGPWNTKDDYWNPSATRQMWKNLPQGKPEAQAAYQDGYNG
                     GKDEFGRKVANPAGIDLADGTFWDGLKMTDNGWVNVSYLWTGSGPTGVVSTAGDPMNVR
                     ASASTSAAIKGLAANYAKVNIECYVEGETVTGKFGTSNIWDRIGPGHYISDTYLQTGSD
                     LPVAPKC"
ORIGIN
        1 taccgcgccg atctggcggc catccgcgag gtggccgggg accggctcct cgtggtcgac
       61 gggatccagg gcttcggcgt gaccgaggcg ccgtgggagg tcgcggacgt gctcgtcgtc
      121 ggcgggcaga agtggctgcg ggcgggctgg ggcaccggtt tcgccgtgct gtctcaccgc
      181 gcgctggagc ggatggagcc gatcctttcc ggctggaccg gtgcccgcga tcccggcctg
      241 ttcgacgacg agatccaccc ggccgacgac accgcggccg cgtggtcgat ctcgaacctg
      301 agcccgatca cctcgggtgc gttcgcggcc gcgctggaac tggtcgagga ggcgggtgtc
      361 ggcgccatcg ccgggcggat cgccgaacgg gtcggcgaac tcgaagacgt cgtgaaatcc
      421 gttggtggcg aggtggtttc ggccgtcgag cgacgggccg ggatcctcgc cttcaccttg
      481 ccggggcacg cggccgaaca ggtggggtcc gcgctggcga gcgccgggat cgccgcgacc
      541 gtgcggccgg aacacgtccg gctgtcgccg cacgcgtcca ctccggcgag cgcggcggaa
      601 caggtgcgtt ctgtgttgga acggctgaag aaaccggccc ggatcttcga gacgcccgtc
      661 atcgcgtcca cggcgtccgg cgatctgctc accgcgctcg tcccggcggt gcacgcgctc
      721 gcggcgatgc tggggccggg caacgaagtc ctgctgcacg atctgagcag gctgccggat
      781 tcgatcgtcg ccatcgcggg cgacctcacc ggccggacgg tcggcggacc gatgacggat
      841 ctgctgctcg ggctcgtccg gcgcggcacc acgcaggatc tgacgaacta cgagacccac
      901 ggccccgacg ggcgcgcgat ccgctcgtcg acgttgttcc tgcgggacgc ggacggggtc
      961 gcgatcggct gcctgtgcgt caaccggctg tccgacggcg cgccgaaggc cgacgggcac
     1021 gaacccgaga cgttcccgcc cgacgtcgac agcctgcagc gcttcctggt cgggcgtgcg
     1081 gtggcgaagg ccgggatccc ggtggacctg atgaagaaac ggcacaaggc ggccgtggtc
     1141 cgggaactgg acgaggcggg cttcttcctc atcaaggact cggtggacca cctcgccggg
     1201 gaactcgacg tcacgcggta cacgatctac aactacctga acgagatccg gggcacctga
     1261 cgcgcgtgct atgaaaggtc ctttccttgc aaattttgca aggaaaggac ctttcatagc
     1321 actggggagc tacgcgagga aggactccac cgcgtcggcg gcccgatcga tcccgccgtt
     1381 cccgcgggtc tcggcccgca cctcggccag gcgcgcggcc acctcgggcg acccggcgac
     1441 ccgctcgaca gcggcccgca gcgtcgaggc cgtcacctcg tcggccggaa gttgctcacc
     1501 gacgccgagt tcggccagtt tcgccgcgtt gccgaagccg tcggtggcca gcgggatcgc
     1561 gacggtcggc acgccgtacc acagcgattc cgtgctgccg cccataccgg cgtgcgtgat
     1621 gaacgccgac gcggcctcca gcaccgcgag ttgcggcacg aaccgatgga cctcgatgtg
     1681 ctccggcagc ggcccgagcg aggccggatc ggtctggccg atcgagatga ccacgtgcca
     1741 gtccgagtcg cggaacccgt ccacgcaggc gcggaacagg tcgagctggt cggtgaacgc
     1801 cgtgccgagc gacatcagga ggactttccg gccgttcgac ggcggggtcc agctccggtc
     1861 ggcgaggcgt tccgggtcca gcgccgggcc gacgaaccgg accgtcgatg gcacccgttc
     1921 gacgttcggc tgcatcgcct tcggcagcag tgcgagtacc tggggcggat gggagatcca
     1981 gtcccaggcg tcggcctcga tgccgttttc gttcagccag cgggtgaaag tggcgaaata
     2041 gtcctttccg gacggtgagg tccggatcgc ggtgatgatc tcacccatgt cctcctcgta
     2101 gccttcccag gcgacgtacg tcggggaaag ctgcaccgcc ggcacgccgt agcgcctggc
     2161 cagcagcggc gccggaagcc cgccgatgtc gtacagcagc aggtccgggc ggttctcgtc
     2221 gtagaaatcg gtgagcaccg gcatcgcctg gatgccctcg tcgaggaaga cccgcatctg
     2281 cgacgccgga tcctccggcc acgccgcctg gtcgccgagc gggaggatcg acgggtgggc
     2341 gacgacctcg gccccggtcg gctcgatcag cccggtgagc ggctcgccca cggcgtagct
     2401 gacccggtgc ccgcgagcga ccagctcacg gatgatcgcc agcgagggat agatgtgact
     2461 cggcgcggtg gagccgatca tggcgatgtg ctggttctgc atgatgtcct gtctgaatcc
     2521 gtggaggaac gtcagacggc gtgcagaaaa ggggcctccc gatcgcgggc ggccctgcgg
     2581 tcacgccgtc tcaggcggtg cgcaggcgga tgaagtagat catgatcgac agcctagcga
     2641 ggtcggcgaa gcatcccaac cgattaaccg gttgcccggt ttgccgcgat cgggacccgc
     2701 cgttggtagg gaccttcgcc ggaaggcttc cgcaggtcac ggacgtggat agggtttcgg
     2761 ggctttcacc tttggaggga aagggagaaa ccttgagacg tgttctcatc accgcgctgg
     2821 ccgcggccac gctcgcctcg gtcgcggtga ccgcgccggc cggcgcggcg gaggcggcac
     2881 agcccgtcga gtcgatcacc tggggagcgt gcaccgaccc gacgttgatc aacgccggcg
     2941 ccgaatgcgg ctacctgtcc gttccgctgg actattcgag gccgcgcggc gagaagatcc
     3001 agctcgcgct cagccgcgtc aagcacaaga cgcccgacgc gcagtaccag ggcgtcatgc
     3061 tcaccaaccc cggcggtccg ggtggctccg ggctgctgct cgccacccgc ggcacccgcg
     3121 tgccgaaccg cgccggtgac gcctacgact gggtcggctt cgacccgcgc ggcgtcggct
     3181 ccagcaagcc ggcgctttcg tgcatccccg actacatgga ctacaaccgg ccgaactacg
     3241 tgccgaccac gcggcagctg gagaagacct ggctgcagcg ctcgaagtcc tacgccgacg
     3301 cgtgcgcgga gaagaacagc cgcgcgctgc tggagaacat caagacgacc gacacggtca
     3361 aggacatgga aagtatccgc aaggcgctcc gcgtggagca gctgaacttc tacgggtact
     3421 cctacggcac ctacctcggc caggtctacg ggacgctgtt cccgcagcac gtccggcgga
     3481 tggtcctcga ttccactgtg gacccccgca acgtctggta ccaggcgaac ctcaaccagg
     3541 acgtggcctt cgacgtcaac ctgaacatct ggttcggctg ggtcgcgcag cacgacggcg
     3601 tctatcacct cggcaagacg caggccgcgg tgaagcaggt cttcaatgaa caactgaaga
     3661 aggtggccgc cgtcccggcc ggtggtttca tcgggccgga cgaactcctc gacgtcttcc
     3721 agcaggcgtc gtactaccag ctgcggtgga cgctgctcgg cgacgcgctc gcgaagttcg
     3781 tcaacaaggg cgactggcag acgatgaagg gcctgttcga ggccttcggc ggccgcggtg
     3841 acgacaacgg gtacgccgtc tacctcgccg tccagtgcac ggacgtgaag tggccgccga
     3901 gctggcagca gtggaagcgc gacaactggc ggacgtatga aaaggcgccg tacttcacct
     3961 ggcagaacgc ctggttcaac gcgccctgcc tgttctggcc ggcgaaaccc ggcaagccgg
     4021 tcaaggtcga cggctcgaag gtgccgagcg tgctgatgat cggcgagacg ctcgacgcgg
     4081 cgacgccgta cgagggcagc ctcgaggtgc gcagccggtt ccccggcgct cgcctgatcg
     4141 gtgagccggg gggtacgagc cacgccatca ccccgcgcgg aaacgcttgc gtcgacaacc
     4201 ggatcgccga ttacctggcg accggggcgc tgcccgaccg caagccgggg cgcacggccg
     4261 acgtcgaatg cgcgccgctg ccgctcccgg tgccgcctcc ggcacccgct tcggcccccg
     4321 gcacggcact ctcccgggtc cccgcctaaa ggatgcgcgt gaaggccccc ttccctcggc
     4381 tcagccgagg gaagggggcc ttcacgcgct ccaagctttc cgagtcaggg gactttgtgt
     4441 tacaaagtgc gagtgagctt tgtagcgcag agtgctcgaa gggggagagt aatggcggac
     4501 gcgttcagcc tcgaagggct ggtcaagcgc ttcggtgacg tcctggccgt cgaagacgtc
     4561 agtgtgcggg ccgcgccagg ggaggtggtg gcgctgctcg ggccgaacgg tgcgggcaag
     4621 tcgaccacca tcgacatgct gctggggctg agcaggccgg actccggtca ggtccgggtc
     4681 gccgggctca gcgccagcga ggcgatggac cgggggatga tcggcgcgat ggcgcagaac
     4741 gggacgctgc tgcgggacgc cacggtcgcc gaactcgtcg gcctgttcgc gtcgctgcac
     4801 cggaatccgt tgccggtccg cgaggtgctc aagcgggcgg gcgtcaccga gtacgcgaac
     4861 cgtcgctgcg gcaagctttc cggcggcgag cagcagcggg tccggttcgc gctcgcactg
     4921 gtcggcgatc cggatctgct ggtgctcgac gaacccaccg cggccatgga cgtcgacggg
     4981 cggcgccggt tctgggcgtc gatgcgcgag tacaccgaga cgggccgcac cgtcctcttc
     5041 gcgacgcatt acctcgccga ggccgaggat tacgccgacc gcgtcgtgct catgcggcac
     5101 ggccgggtcg tcgcggacgg tcccgtcggc gacgtgcggg ccgcggtcgc cgggcgggtg
     5161 ctgcgcgccg tcgtcccgga cgccacccaa gccgcgctcg ccgcgctgcc cggggtgtcg
     5221 cgagccgtgt tgcgcgccgg gcacgcggaa ctgaactgtg ccgactccga tgccgcgatc
     5281 cgcggcctgc tgcgcgagtt cccgctcgcc gcgaacatcg aaatcaccgc tgtgggactg
     5341 gaagaagcct tcatcgcgct gaccgccgat gaagctgaag gagccttgag atgaacccgg
     5401 cctacctcgc gttggagatc aagcgcatcg ttcgcagccc gcagttcgcg ttgttcacca
     5461 tcggtatgcc gctggcgatg ttcctgttgt tcggcgggat cttcggcgcc cgcgagatcg
     5521 cccctgggat ctcgaccgcg accgtgacca tggtgaacat ggccgcgtac ggcgccatga
     5581 ccgccgcgct gttcaccggc acccgcgtcg ccaccgaacg caccgacggc tggcagcgca
     5641 ccctgcggct gacaccgttg cgggcgcccg gttacctgat ggtcaaggtg gcggccggat
     5701 tgttcgtcgc cttgcccgtc ctgctggtga tcttcgcggc cgggatgatc cgcggcatcc
     5761 ggctcgaaac cggccagtgg ctcacgatct tcggcacgct gtggctcggg acgctgccct
     5821 tcgccgtact gggcctgatg atcggcctgt tcggcaaggg cgacaccgtc caggccgtga
     5881 ccggcgcgct gatgctgccg ctgggcatgt tcggcggatt gtggatcccg ctgcaggtcc
     5941 tgccaggctg gatgaacacc gccgggcacc tcatgccgac gtactggctc ggcgagatcg
     6001 gccgcgcgcc ggtgctcggt ggctcgggcc tgctgaccgc cgccggagtg ctcgcggcgt
     6061 ggctggtggt gcccgcgctc gtggtgatgg cgaggttccg gctcgacacg gcgaggctgt
     6121 gaacccgtgt tagttttccc aagtggtgga ggatgaacgg gacggcgacg agcggccgat
     6181 gacgcccgag gagtcgctcg cgctcatcgc cacgcaggcc gagcggaccc ggcgcgagat
     6241 cgggccgaat ccggccgtgc tgctcggcgt ctggggtctg gtgtggctgt tcggtttcgg
     6301 gctgatctac gtctccgccc cgccgaccgc cctgatgccg ctgtgggtcg ccgccgtgct
     6361 caccgtcgtc ggtttcgccg gggccatgac gtactcggcg atctacggca tccggtcgag
     6421 ccgcggcgta cacggcccgt cgcggctcgt cggcgcgatg tacgggtgga gctggatgat
     6481 cgcgttcggc gggctgacgg tggtgaacac cgcgctgatc cggctgggca tcgacgccga
     6541 cctgatcccg ttgctgtggt ccgggaccgc gctcatgctg accggcctga tgtacctcgc
     6601 cggcggaatg ctgtggcaga gcaaattgca gtacggcctc ggcgtgtgga tcatcgcgtg
     6661 cggcgcggcg agcgtgctgg ccgggggacc gtacaacttc ctcgtgctga gcgtcgcggg
     6721 cggcggtggc ttcctggtgg cgtccctggt cttcctggta cgggcgcgat gagcgaggac
     6781 gggctgcccc agctcgatcc ggtgatccac gcgcaggcgc ggctgcgggt cacggtggcc
     6841 ctgtcgagcc tggggccggg ggacagcatc accttcccgc ggttgcagca actgctggac
     6901 atgaccccgg gcaacctgtc gacgcatctg cgcaaactcg aggacgccgg ctacgtcggg
     6961 atcaccaagg ccttcgagca tcgcacgccg gtgacgctgg tcgagctgac cacccggggc
     7021 cgggccgcgt tcgaggagta cacgaaggcc ctgcaccgtc ttctcgaggt accgggcgat
     7081 gggcgggcat gaccggtggg tcatccacct ggacatggac gcgttctacg cctcctgtga
     7141 acagctgacc cggccgaccc tggcgcaccg tccggtcctg gtcggcggcg cgggcccgcg
     7201 cggcgttgtc gccggggcga gttaccaggc gcgcgaacac gggatcaaat cggcgatgcc
     7261 gatgtcgcag gcccggcggc tgctgccgcc gaacggggtc atcctgccgc cgcggttcaa
     7321 actgtacgag ctgctgagca cccgggtgtt cgacctcgtc gccacgtacg cgcccgtgct
     7381 ggaacggatc tccctcgacg aggccttcgc ggaaccgccg tcgctggtcg gcgcgtcgtc
     7441 ggaagacgtg cgggagttcg gcgcgcgcct gcgggagcac atccgctccg acatcggcct
     7501 ggtcgcgtcg atcggggcgg cgtcggggaa acaggtcgcg aaggtcgctt cggatctggc
     7561 gaaaccggac gggctgctcg tcgtcgacca gggcaccgaa cgcgatttcc tcgccccgct
     7621 gccgaccagg gtgctgtggg ggatcggccc ggtggcggag gggaaactgc gggcgatcgg
     7681 cgtccggacg ctggggcagc tgaccgcgct ctccgacgcc gacgcggtgt ccactctggg
     7741 cagtgtggtc gggcgggacc tgcggcggct ggcgaccggc gtcgacgacc ggccggtgtc
     7801 cgaccgtgcg gagctcaagc aggtcagcgc ggagacgacg ttcgaccggg acctgatcga
     7861 cctgccgagc ctgcggcgcg aggtccgcga cctcgccgtg cacgcccacc ggcggctcgt
     7921 caacgccggc cgggtcgcgc ggacggtggt ggtcaaactg cggcacaccg atttcagcac
     7981 ggtgacgcgt tcggagacga tggcctcgcc caccgacgaa ttcgaccagc tcgccgcgat
     8041 ggcggaacgg ctgctgatcg acccgaccga attcggcggg gtgcggctgg ccggtgtcgc
     8101 gttgtccggg ctttcggtgc cgcatcagga tccgctcttc acgctttccg tgccggcccc
     8161 ggacgtgccg gtggtcgagc gggcgcccgc gccggtaccc gtggtcgcgt cgagctggcg
     8221 gcccggcgac gacgtcgtgc acgacgagtt cggcaccggt tgggtgcagg gcgccgggca
     8281 cggccgggtc accgtccggt tcgagacgcg atccagcggg cctggggtcg cgcggacctt
     8341 cacgcaggag gatccggcgt tgcgacgggg agaacccggc gactgcctgg cctgagggcc
     8401 ccgtgatcag acggcgaact cgcgtgattg agcagcgaac tcgcgtgatt gaagagcgat
     8461 cacggtgtgc ggcccctgat cacgcgagat acgcgtctga tcacgcgaaa ttcgagctgg
     8521 tcaccttcac ctcacgcggg cagttacgcg gcgacgccga aagcgaccag gcttgacgct
     8581 gtccagtgac cgcgcgtaag gcaggatgga ggagactgtc acccgatcga gggaatcgat
     8641 gttcagctcc cgcgtccgtc aagccaccgc cctcctcggc gccgccgtcc tgctcgccgc
     8701 gtgcagcggc acccctgagc agcggcaacc gcccgccgca cccccggcgc cgcaggcgag
     8761 ccaggcgccg gacgggtcgt tcaccgtggt cgccaccggt gacgtgctga tccaccccgc
     8821 gctgaccgag caggcgaagg aggacggtgg cggcaagatc gactaccggc cgctactggc
     8881 cgggatcaag ccgctgatct ccggggccga cctcggcatc tgccacctcg agaccccgct
     8941 cgcgccgaaa ggcgggccgt acagcggcta cccgtccttc agcgcgccgc ccgaaatcgt
     9001 cgacgcgctc aaggacaccg gatacgacaa ctgctcgacg gcgtcgaacc acacgatcga
     9061 ccaaggtgtg gacggcgcga cccgcacgct cgacaaactc gacgaggcgg ggatcaagca
     9121 caccggttcg gcgcgttcgg ccgaagaggc gaaaaagccg ctgatcgtcg acgtcaacgg
     9181 tgtcaaggtc gcgcagatct ccttctccta cgggttcaac gggatcaagg tgcccgcggg
     9241 caaaccctgg ctcgtcaacc agatcgacgc cgaagacgtg atcgcccagg ccaaggccgc
     9301 gcggaaggcg ggcgcccagg tcgtcctcgc gagcctgcac tggggcaccg aataccagca
     9361 cgacccgacc gccgaacagc gcacgctggc gaagaaactc ctcggtgacg actcgatcga
     9421 cctgatcatc ggccaccacg cgcacgtcgt gcagcccttc gagcagatca acggcaagtg
     9481 ggtcgcctac ggtctcggca acagcgtcgc ccggcattcg gaaccgaagg gctcgaccga
     9541 acagggcgcc gcggcgcggt tccggttcgt gcgggacggc gaacgctgga aggtcgacaa
     9601 ggccgaatac gttccgacgc tggtccagct cggcccgccg atccggctgc tcgacctgac
     9661 cgcgggaccg gccgggaacg ccggcgcgga agcgctcaag gccaccgacg aggtcgtcct
     9721 cagccgtggc gccgcggaca agggcctgac ccgtcccggt cgctgagctg agtgtctatc
     9781 ggtgaacccg cgtccgcgat cgacgtcggc aggacgctgc ctggccatgc acctcacgat
     9841 ggcggatcag gcgtcctgcc accgcgatag cggggccttc ggccgtggcg ggttcacgcg
     9901 ttcaggccct tttcgaagtg tgtcttcagc tccgccgaca agctctgagg ggacaggggt
     9961 gggctcttcc ccgcccaccc ctgccttacc gcgcccgcct tcaataacgt cgccgcacca
    10021 ccagtttcgc gagggccgcg agctcggcgc ctgggcgggg caccgggttc gagacggcga
    10081 gatggtgcag cgcgccggtc aggagcgcgt cggcctgctc ctggctccac gtccggccgc
    10141 ccgcccggtc caccagctcc gccgcgtggg gcaactccgc ggcgtcgagg ctttccttgc
    10201 ggtacaaggc atccagctct cgcccggcgt ccgtccccga gtggagcgcg gccaccaccg
    10261 gcagggactt cttccggttg gaaagatccg agtggaccgg tttcccggtc accgccggat
    10321 caccccagat cccgaggaga tcgtcgatgt gctggaacgc cagcccgagt gccctcccgt
    10381 actcggtcag ccggtcgatc tgatcctgcc tcccttctcc ggccagcgcc ccgagcgtgc
    10441 acgacgcccc gagcaacgcg ccggtcttcc cctcggccat gcgaacgcat tcggcggtgt
    10501 cgacgtcacc gcgttcttcg aacttcagat ccgcgctctg cccttccagc aggtcgatca
    10561 cggccgtgct gagcacccgc aacgcggtct gcccgaacgg ggccagcacc tcgaaggccc
    10621 ggcacagcag ggcgtccccg gcgaggatcg ccgcgccggt gccgaaaacg gtccaggccg
    10681 tcggccggtg ccgccgcgtg gtgtcggagt ccatcacgtc gtcgtgcagc agggagaagt
    10741 tgtgcaccat ctccaccgcg acgcccaccg ggacggcgat ctcggcgtcc ccgccgaccg
    10801 cttgagccga caacaacgcc aatgcgggcc gcaaggcctt cccactgtcc gaagtggacg
    10861 gacggccgtg ttcgtcccac cagccgaagt ggtagccggc gatgagccgc atcgactcgg
    10921 gcaatccgtc gacggcttca cgcagtgccg gatcgagcag attccggctc caggtcagta
    10981 cctcaccggc gggccgggcg ccggtatggg tctcgatggt cgtcaacgga ctccctttca
    11041 ttcgacccgg tgagccgcga tttttcgcaa ttcgcggata cccattcgag tggggtgggc
    11101 gcaaaatcaa catagcaagg ggtaatgccg ggtcaaacag ctcgatcggg tctacggaga
    11161 ggttcacctg tttgccggat tgggccggat gcgcggtgcc gggcggccga tcgggtgccg
    11221 tcaccgcacg aaatgccggt acggggcgtg ggtggtgacg tctcgtggtg gccgctcact
    11281 cggtcgtgaa gccgcgctct ccgaccggtg acgggccttt ccggcgcgtg tcggaaatgg
    11341 tttcgagtcg tgggaaattg ggccgagccg gtgatgatcg actggcgtcg gtccgccgca
    11401 ggtatgaatt gattcaaccg gtcttttccg ttcggcgaag cgtgaactag tttcagcagt
    11461 ctccgcctgg aaggactcga atgggcattt acctgaccgg catcgcctgg gtcgtcggcg
    11521 cggcggccct cgcgggtctc gtcggctacc tcgtccgcaa attcggctgg gacgaaggac
    11581 ggcccgacaa caacgacgcc gccggccagg tgttcaccat cgtcggcggg ctgcacgccg
    11641 tcctggtcgc gttcatcctg atctccctct tcgactccgc gagcgcggcg cgcgagggct
    11701 cgtaccacga ggcggacagc ctggtcgccg ccgtctgggc cgccgactcg ctggggaccg
    11761 aggtcaagga cgaggtgcgg aagctgagca ccgagtacat gaccacggtc gagcagaagg
    11821 aatggccgct gatggccggg ggcgagacga cccttccgga caccggctgg acgctgctcg
    11881 accggttgcg caaggcggtg gacaaggccc cgacggacga cgactggctc cgcgagcgca
    11941 agaccgaggc gaacacgcag ctctggcagg tctacgaggc ccggcaggag cggctcaacg
    12001 cggtcgtggg cggccgggtc ggcggcgtcg tgtggttcgc gctcattctc ggcagcctga
    12061 tctcggcact gctgcccaac ctgttcggcg gtacccggct ggccgcgcat ctggtgatcg
    12121 tgtccaccct ggccggcacg gtcacgttgc tgctgttcgc gatctaccag ctgcagaacc
    12181 cgttcggcgg tggggtgcgg atcccgccgg acgcgttctc cgccgcgctg gcgaggatct
    12241 cttgagccgg tgagcacagt ggaccggatg acccgggggg cggcgacggt ggccgtcgcc
    12301 gggctggtgg gggcgtcggc gctcctggcg ccgatggccg cgcgagccgc cgagtcctgc
    12361 ctggcggtgc aggcggaaac cgggtcgtac gggaagtcga agctgcgctg gctcgacgtc
    12421 ggctcgggta cgacgtcacg ggtgaccgag ccgggctacc ggctcaacgc gctcggctac
    12481 tccgcgacac ggaatctggt cttcggcgtc gccgaaggac tcagccgggg cgcgcacgcg
    12541 gtgacgatcg accgggaggg gaagacccag gatctcggcc cgatcacccg cgccgggaac
    12601 cggctgccgc tgtggagccc cgtcgcgggc gtgaccgccg gcgcgatcgg cgggaattcc
    12661 tggtacctgc tcaggaacgg cacactgtac acagtggact tgacgccggg ggagcggtat
    12721 ctgcgggtga tcgggacggt gttcctgcgg ccgatcacac tcgcccacga cgtcaacgat
    12781 ttcgcgtacc acaacggatt gctgtacggg gtctccacca cctggcgcgg aaagggcgcc
    12841 gtgatcacca tcgacccgga gaccggcaag gtccgtgagg ccgaagacgc gcgtttcccg
    12901 cccgccgacg tctacggctc ggtcgtgctg ggccgcgacg gtgccctgta cgccacggcg
    12961 aaccggatcg gcgggcgcag cgtgctctac cggctggacc ggagtgggca ggtgaccgtg
    13021 gtgctctcgg gaccgccgct ggcgggttcg gacgccgcgg gctgcctcac cgcgcccgag
    13081 ccgcccaaac ctgaaccacc caaccctgaa ccgcccaaac ccgagccgcc gaagccgacg
    13141 ccgacaccta cgccgacatc ttctccttcc cccacaccta cttccagttc ctcgccgccg
    13201 tcacccagtc cgtcttcttc gccgagccct acgccgtcgt cgagcccggc gcccaggtcc
    13261 gctccccagg tgatgccgca gccgccggtt tccgcgccga ggccctctcg ttcggtggcg
    13321 cccagggaac ggaaggaagc ggcggaggag gtcgacccac acgcccgtac gaaggagaaa
    13381 cggcgctggg gattgaccgc gctggtcctg atcctcggcg gtggcgcggc ggccggtgcc
    13441 gtccggcggg cccggtgagt cagtacttga actggtccac gttctcacgc gtgatcagga
    13501 gcgggtcgcc cagcagcagg gtcttcgtgt cttcctcgta cttgatcgcg gggagttcga
    13561 ggttgacctt gttcgacggg ccgggctgtt tgccctcggc gacctgcttg cccgcccagg
    13621 cggtgaggta gccgagcgat tcgacattcc acagcaccga aagcgacgcg gaaccgtcca
    13681 gcaggtacgg cttgatcgcc tgcggtgtcc cgacgccgac ggtgaagacg cggccgatct
    13741 tctgctgcga gcggaccgct tcggcgacgc cgggcgcgga cgtcgtgcat tcgccgacca
    13801 ggccggtgag gtccgggtac ttggtcatca gctgtttggc cagcgcggtg gcgttgtcct
    13861 tgtcctcgcc ggcgtagacc gtctcgacga gctgcgcatg ggggtacgcc gtagcggtat
    13921 aggcacgctg aacggcgatc cacgcgttga ggttctcggc ggtctcgcca caggagacga
    13981 tcgcgtactt gcccgcgttc cccatcttct tcatcagcgc gtcggtgagc gccttgccga
    14041 tgccttccgg ggtcgcctga ttgacgaaga gttcgcgatc ggtgccgggc gcgtcggtgt
    14101 ccgaagtgat cacgtggaca cccttggccc gcgcgtcggt gatcgcgggc gcgatcgccc
    14161 tggggtcgtt cggcgcgatc gcgatgacgt ccacctgctg gtcgacgagc ccacggacga
    14221 tcgagacctg cgccgcgggg tccaccgtgg ccggaccggt cgagctccat tcgacaccga
    14281 gctgcttggc cgcggcctgc ccgcccgtgt tcatcgcctc gaagtacggg atgccggcga
    14341 ccttcggcac gaacgcgatc cggatcggcc tggccgccat gcccgccggt tcttcgccgt
    14401 cacagcccgc cagcccgaac accatgccca aagcgagcac agtggcaacg acgagcgtct
    14461 tcgtcggccc tcgcatctcc accccatagt cacggaacca tctgaaccag ccgatcggtc
    14521 tacgcgcggt ggagacctcc ggcgaaacta gggctcctgg ttaccccggt caaccggatg
    14581 agcgcaaagg gttacggaag tgagttcatc gacctgggac gattacccag tcggcctacg
    14641 ggggtgacgg tgagcgacga ctcatcgcgc gttttatacg ggcggggggt atggtctcgc
    14701 gtatggatga cgcaaggcat ggagcaagct ggtcgatggc ggtgtcggcg accctgcact
    14761 gcctcaccgg ctgtgcgatc ggtgaggtcc tcggcatggt catcggtacg gcgctcggct
    14821 tcggcaacct ggcgacgatc gtcctcgcgg tggcgctcgc cttcgtcttc ggctacgcgc
    14881 tgaccatgcg cggcgtgctg aagtcggggc tgccgttcgg cgccgcgctc aaggtggcgc
    14941 tggccgcgga caccgtgtcg atcgcggtca tggagatcgt cgacaacgcg gtcatgctgg
    15001 tggtgccggg cgccatggac gccgggctcg gaagcctgct gttctggggt gcgctggcgt
    15061 tctcgctggc cgtcgcgttc gtgctgacgg tgccggtgaa caagtggatg atcgggcggg
    15121 ggctggggca cgcgaaggtc cacgcgcacc acggtggtca ctgagcgagc ttcagggtct
    15181 tcgcggcaag gagggttatt gagaggtgag ttgaacatgg cgtgatgggg ttggtggcga
    15241 gagcatgctc accacggaga cctggcgcgc tctcgactgt ccacaaggga cacattcaga
    15301 ggcaaaatgc ccgatttggt cactttgtgc aggggtcgtg agtgatttgg gtggttctaa
    15361 ccctcattat cactcacgac cccgttcgga agcggacata aaggtgcaac cggatgcccg
    15421 atcggcgcga tatgtccctt gtggacgctc gggatcaggc ctgtcggcat cgccagtcca
    15481 gggtcagacg ctcgacagat cgatggcccg gtcgatctcc cgcggcatca gcacccgcag
    15541 aatcccctcc agcaggtagt agtcgccgta cggcaacgaa acctcgacgc cgtcctcggc
    15601 ccgccggttg cgcgtgcccc gcgccatgat cgcctcggcc cgcgtggatt tcgcggtcag
    15661 gcacgtgtcg cacagcgcgg tgaggatccg gatcgccgct tcgcggtact gcggccggtt
    15721 cgccaccttc gccaagtcaa gcagcccgca cgccatcacg gcgccggcgg aggagtcctt
    15781 gatgtcgtag ggcgcctgcg gtgcgaggta atcccacacc ggcaggttgt ccggagtcag
    15841 cgcgtgcagc gcgaagtcgg ccatgcgttg cgcggtccgc aggaacaacg gttccccgga
    15901 gcgccggtac atcgtggtga acccgtagat cccccaggcc tggccgcgcg accagcacga
    15961 cgtcgggctg taaccctgca cggtttccgg cccgatctcg gcgccggtgt ccgggtcgaa
    16021 gtcgaacacg tgcggggtcg agccgtccgg gcgcacgaag acccgttcgg tggtcttcgc
    16081 gtgcgagacg gcgatgtcga ggtacttccg gtcgccggtc tgtttgctcg cgaaggtcag
    16141 caggtccagg ttcatcatcg tgtcgacgat gacgcggccc gcgttgcccg gggtgccgag
    16201 cgcgccccat gcccggatga accgcccctt ttcgttgtag cgctggatga gcgacgcggc
    16261 ggcgttgagc gcgccggcgc gccacttctc gtcgccggtc agccgccagc cggtcaccca
    16321 cgacgggtag aagaggaatc cgaggtcgtg gtcccgtgtc tcgtattgcc gcggcgcgag
    16381 cttttccgcc gacgccatgg cgagcgtgcg gaatcgcgca tcaccgctgt agatcgaggc
    16441 gagccacaat gtgcccggcc agaatccgcc gatccagccg ccgttctgcg aataggtcca
    16501 tttctcgaat cgggtgatct ccggaaaggc cgtcacgccg ggggcgacgg cgcgcagttt
    16561 ggtcaccgcg taatcggccg ttcggcggaa agtccgcagt tccccggccg cactggcggc
    16621 cggggtgatc gtcgtcgtcg ccgcgacggc ggcaccggcg gcggtggtca agagggttcg
    16681 ccgggaaacg ctcaccatgc ccgccaatcg tcagtgggaa atgcgtgacg ggagtttcgc
    16741 acgacgatta cgggcttgtg aagagcgttc atggttgtga ataaatgcgt cactcagcgg
    16801 gacggatgtt cgcgttgtga tggaacacgt tgtccgggtc gtacaccgcc ttgatggcgg
    16861 ccagccgggc gtatttctcc gcgccgaacg ccgtgcgcac gcggtcttcg tcgtattcgt
    16921 tcatgaagtt caggtagccg ccgtagttgt tggaatgcgg caggagttct tcccacagcg
    16981 cacgcgccca ggcgcggtcg gcggccagga gttccggtgt cggggcggtc gccgcgaggc
    17041 cgatgacgaa cccgggcgtc cgcggcccgc cgaacgcggt cgcgtcgtcg ggcaccgtcg
    17101 agaaggtgtc ctgcaacggc acgatcggca tgacggtcgt cggcgacgcc ttgtccggca
    17161 ggcgcgcggc gatcacgtcg atgacctttt cggacagtga ggagacgtaa agcgacttct
    17221 cgtaggcgag gatgccccgt ggcgcggtcg ggtcgagcag tttctgcagt tccgcgtacg
    17281 gcatcggggt gacgagctcg aacgccgcgg gcagcccgtc ccggatccgc tcgacgatcc
    17341 gggcgtgccg ctcggggccg tcgaagccgg cgacgaccag cgcgagcccc ggcgcgaggt
    17401 ggtgctccgg cgggacgaac ggcgcgggcg gcgcggtgat cccgacgagc atcgaaccgg
    17461 tgcccggcgg cagcgtcgcg gtcacgtcct tcgcgaagcg cagtgcttgg ggcgcgtcgt
    17521 gcagtgtcca gaagaacagc ccgacctcgg cgaggccgac ccggtgcagc cggaactcga
    17581 attccgtgac cacgccgaag ttcccgccac cgccacgcaa ggcccagaac agatccggat
    17641 gctccgcctc cgacgcccgc aggatccggc cgtcggccgt cacgacctcc gccgaaagca
    17701 gattgtcgat cgtgagcccg tgtttcgccg tcagccagcc gaagccgcct ccgagggtga
    17761 gcccgccgac gccggtgtcg ctcaccgtgc cgcccaccgt cgcgagcccg taccgctgcg
    17821 tcgtttcgtc gacgtcggcc cagacggcgc cgcctccgac caccgcggtg cgggcgccgg
    17881 gatcgacggt gatccggcgc agcccgccga ggtcgatcac cagaccgtcg tcggccacgg
    17941 cggagccgct gaaactgtgc ccgccgccgc gcaccgtgat ctcgaggccc ttttcgcggc
    18001 cgaaggccag cgcggtgacg acgtcttcgc gggtggcgca ttcggcgacc accgccgggc
    18061 gccggtcgat gtcgccgttc cacacggcgc gggcggcgtc gtaaccggga tcggcggcgg
    18121 tgatcaccgt gccggagagc ttctcgcgca acgtggtcgt ttcgggcgga ttcatgggac
    18181 cccctcaggt cgtggctacc gccagtctcg atggcggacg ccccggcccc aggtccgcac
    18241 gagcggcgga aagggcggac aaaagggcga aggcccggcg ttatggggta cgccgggcct
    18301 tcgcgatcag gagtgcgtca gcacttgggt gccaccggca ggtccgagcc ggtctgcagg
    18361 taggtgtcgg agatgtagtg ccccgggccg atccggtccc agatgttgct ggtgccgaac
    18421 ttgccggtga cggtctcgcc ctcgacgtag cattcgatgt tgaccttcgc gtagttcgcc
    18481 gcgaggccct tgatcgccgc cgaggtgctc gccgacgcgc ggacgttcat cgggtcgccc
    18541 gccgtgctga cgacgccggt cgggccggag ccggtccaca ggtaggagac gttgacccag
    18601 ccgttgtcgg tcatcttcag gccgtcccag aaggtgccgt ccgcgaggtc gatgcccgcc
    18661 gggttggcca ccttgcggcc gaactcgtcc ttgccgccgt tgtagccgtc ctggtacgcg
    18721 gcctgcgcct cgggcttgcc ctgcggcagg ttcttccaca tctggcgggt ggccgacggg
    18781 ttccagtagt cgtccttggt gttccacggg ccgacgtccc acaccggcgc gtattcgcag
    18841 cggctgttgt cggtgcggca gatgcggacg gtgtagttgc cggtgttctt cggcgccagg
    18901 ccgcggcccg aggggagcgc gacgaagtgg tcgcgggact tgatcacgtg cccgttggcg
    18961 gtggtgccgc cgacgaggcc ttcgcgggtg ccgtagacct tgtacgtcag cggggccgcg
    19021 gccgcgccga tcgcgttgac ctgcggggcg agctcaccca ggagggtgac gtcgctgacc
    19081 ttcgcggtca cgccgtcgtg caccgtgcgc agtccgacgc ggacctggac cgtggagacc
    19141 gaagcggaca gctgggtgcc gccgtcggcg ggcgtccact ccgtccagtc ctgcgagttg
    19201 agcttgccgc ggacgtcgac ctcgacctcg gtgcccttcg gcgcgtcggc ggtcacctgg
    19261 gcggtgaccc ggttgaccgg cttcccgagc ttctgctcgg ccagcagcag gtaaccctgg
    19321 ctgccgatgg agtcgggttt tctgtgccag gcggcgtttt ccaggctgag cacaccgccg
    19381 tcgctgcgga cgttgacgtc atctccgtcc acagtggaca ggtcggcgcg ccagcttcct
    19441 tcgggcgcgg cgttcgcggg gctggcggcg agcgcggtga ccgcccccat ggccagcacg
    19501 gccgccatca cccggcgggc cttcacggtc cggaccattc cggtctccct tcgagcactc
    19561 tcggttgcta cgaagggagc ttcgccgggg cctgtacacg atcgatacaa acgcaagtcg
    19621 gcacctgatc gcggtgcgtg aacaccgcga tcaggtgccg aaaggtgaga aggtcaggcg
    19681 ctcgcggagt cgttgtagga cgcttcggcc gactcctgaa ggcgtgaagc gagcgcggat
    19741 tcctgcggcc gggcggagag ttcccgccac aacgccagcg cgcgttccga ataggtccgc
    19801 gaccgctcgg gctggctcag cgcctcgtgc agttccccga gcaactgcga cacctcggcc
    19861 tcggaccggc ggtccccgtt gcgccggtgc acgctcagcg aattcaccag cagcagttgc
    19921 gcgtgcgcca ggtcgccgct gtgcaggtac agctcaccga gattctggtt cgcgtagccg
    19981 acgcagtggt cgtcgccgag ttcgttgaag aggacgatgg cgcggtcgac ccattcccgc
    20041 gcgcccgcga ggtcgccctg atgctggcgc agcatcgcga gccgcttcaa cgcgtgcgcc
    20101 tcccgatgcc ggtcgccgat ccgggcggac tgctcgagcg cctcggtgaa ccagcgttcc
    20161 gcttcgtcga accggcgccg cgccagccac accgcaccga tcgcgatccg cgcgagggcc
    20221 tcgccgtgcg gatcgcctgc cgccgagaac tggtcgagcg ccgcgtggca gtgctccagc
    20281 gcgacggtgt cctcgccctt gatccgcagc acggtgccga gcccggccag cgcgatcgcc
    20341 gcgccctgcg cgtcgccgac cttgtcgaac agcagttgcg actgctcgaa cgcgaccagc
    20401 gcttcggcgt aactgtcctg gtacagctgg atctgcccga ggttgcgctg gatgatcgcc
    20461 tcgccgcgga cctcgccgga ccgccgggcg gcggccagcg cgacggcgtg cgtgtgcagc
    20521 cagtcgtcct ggtggccgcg ctggtcgaag tacggcgcca gcgcggcggc gagccgccag
    20581 gccagcgcat cgaagccgag gtcggcggcc agcgagaccg cggcgacaca ggtgtgccgc
    20641 tcggcggcga accacgcggc cggatcctcg atcagccgcc cggttccccg cgggagggcg
    20701 ggctgggccg cggtgtcgtc ccggtacagg ccgaagaagt ggatcggcaa ccggtccgcg
    20761 gcctcgatcg cgagcgcgag atagccctcc agcacccgtt tcgtggcgtc gtgcgccttc
    20821 gacggcacgt cctgcgcgcg gagttcgagc gcgtaacacc gcaacaggtc gtgcaagcgg
    20881 taccggggct cgccggtggt gtccgagccg ccgagttcga ccagatgggc gtccaccagc
    20941 acgtcaagga cgtcgtcgcc gtgctcgcgg ccgagcaggg ccgccaccac ccagccgggg
    21001 aactgcaccg aaccgaggcc gccgag
//
