LOCUS       NZ_KB976671            21854 bp    DNA     linear   CON 01-APR-2024
DEFINITION  Bacillus toyonensis strain HuA2-3 acrHg-supercont1.9, whole genome
            shotgun sequence.
ACCESSION   NZ_KB976671
VERSION     NZ_KB976671.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus toyonensis
  ORGANISM  Bacillus toyonensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 4008403)
  AUTHORS   Feldgarden,M., Van der Auwera,G.A., Mahillon,J., Duprez,V.,
            Timmery,S., Mattelet,C., Dierick,K., Sun,M., Yu,Z., Zhu,L., Hu,X.,
            Shank,E.B., Swiecicka,I., Hansen,B.M., Andrup,L., Walker,B.,
            Young,S.K., Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B.,
            Abouelleil,A., Alvarado,L., Arachchi,H.M., Berlin,A.M.,
            Chapman,S.B., Dewar,J., Goldberg,J., Griggs,A., Gujja,S., Hansen,M.,
            Howarth,C., Imamovic,A., Larimer,J., McCowan,C., Murphy,C.,
            Neiman,D., Pearson,M., Priest,M., Roberts,A., Saif,S., Shea,T.,
            Sisk,P., Sykes,S., Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     The Genome Sequence of Bacillus cereus HuA2-3
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4008403)
  AUTHORS   Feldgarden,M., Van der Auwera,G.A., Mahillon,J., Duprez,V.,
            Timmery,S., Mattelet,C., Dierick,K., Sun,M., Yu,Z., Zhu,L., Hu,X.,
            Shank,E.B., Swiecicka,I., Hansen,B.M., Andrup,L., Walker,B.,
            Young,S.K., Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B.,
            Abouelleil,A., Alvarado,L., Arachchi,H.M., Berlin,A.M.,
            Chapman,S.B., Dewar,J., Goldberg,J., Griggs,A., Gujja,S., Hansen,M.,
            Howarth,C., Imamovic,A., Larimer,J., McCowan,C., Murphy,C.,
            Neiman,D., Pearson,M., Priest,M., Roberts,A., Saif,S., Shea,T.,
            Sisk,P., Sykes,S., Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     Direct Submission
  JOURNAL   Submitted (07-DEC-2012) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Taxonomic-Update-Statistics-START##
            This Genome (query)               :: GCA_000399405.1
            Current Name                      :: Bacillus toyonensis
            Previous Name                     :: Bacillus cereus HuA2-3
            Date Updated                      :: 2022-03-10
            Analysis Type :: Average Nucleotide Identity (ANI)
            Analysis 1 (A1) :: Query vs. TYPE genome for current name
            A1 Genome (subject)               :: GCA_000496285.1
            A1 Name                           :: Bacillus toyonensis
            A1 ANI                            :: 99.4201%
            A1 Query Coverage                 :: 83.75%
            A1 Subject Coverage               :: 94.68%
            Analysis 2 (A2) :: Query vs. TYPE genome for previous name
            A2 Genome (subject)               :: GCA_006094295.1
            A2 Name                           :: Bacillus cereus
            A2 ANI                            :: 91.7421%
            A2 Query Coverage                 :: 77.41%
            A2 Subject Coverage               :: 80.96%
            ##Taxonomic-Update-Statistics-END##
            ##Genome-Assembly-Data-START##
            Assembly Method                   :: allpaths v. R41865
            Assembly Name                     :: Baci_cere_HuA2-3_V1
            Genome Coverage                   :: 108.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000399405.1-RS_2024_04_01
            Annotation Date                   :: 04/01/2024 01:17:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,841
            CDSs (total)                      :: 5,738
            Genes (coding)                    :: 5,542
            CDSs (with protein)               :: 5,542
            Genes (RNA)                       :: 103
            rRNAs                             :: 6, 4, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 196
            CDSs (without protein)            :: 196
            Pseudo Genes (ambiguous residues) :: 0 of 196
            Pseudo Genes (frameshifted)       :: 81 of 196
            Pseudo Genes (incomplete)         :: 115 of 196
            Pseudo Genes (internal stop)      :: 62 of 196
            Pseudo Genes (multiple problems)  :: 52 of 196
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:43:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2648187
            Orig. end                         :: 2670041
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB976671.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The organism was changed from 'Bacillus cereus HuA2-3' to 'Bacillus
            toyonensis' in March 2022.
            Please be aware that the annotation is done automatically with
            little or no manual curation.
FEATURES             Location/Qualifiers
     region          1..21854
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21854
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21854
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11854](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11854)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(10..25)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     gene            complement(316..1155)
                     /locus_tag="IG5_RS21440"
                     /old_locus_tag="IG5_02683"
     CDS             complement(316..1155)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002175592.1"
                     /locus_tag="IG5_RS21440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02683"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_002093485.1"
                     /transl_table=11
                     /translation="MSMIQLHVYKEILHFKEDVTPFLEKNEQENNLMLGILQVAQEPTF
                     MGVAKRGEEITVVFLQTEEKIQMIVATSENSEVDIVKLAKELSKVYPDIPGLIGNKEIV
                     QKLAEELAVLENKKTNVVMKQGVYALQQIKKKWNEDGIFREITNDELPLIEKWIYQFCE
                     DVKLPTTKEEAEQTAHTLITNNRLFGLEVDGKLVSVAAKTRPTTNNITVNFVYTPKEAR
                     KKGYASNCVAALSQRMLDEGYKTTTLYTDLANPTSNKIYQEIGYEQIAESVLIFLEK"
     gene            complement(1216..2724)
                     /gene="argH"
                     /locus_tag="IG5_RS21445"
                     /old_locus_tag="IG5_02684"
     CDS             complement(1216..2724)
                     /EC_number="4.3.2.1"
                     /codon_start=1
                     /gene="argH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014895313.1"
                     /locus_tag="IG5_RS21445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02684"
                     /product="argininosuccinate lyase"
                     /protein_id="WP_000813956.1"
                     /transl_table=11
                     /translation="MKQSKEEFIKNEGADFPGKTYVDCVLQHVFNFQYNHLLKDMFQVH
                     KAHIMMLTEESLIKKEEATVILKALKKVEGMPKDQLRYTEQHEDLFFLVEHLISQEAKC
                     DFVSNMHIGRSRNDMGVTMYRMSLRRYVLRLMEHHLLLQESILQLADDHKGTIMPAYTH
                     TQPAQPTTFGHYMLAIYDTMQRDLERMKKTYQILNQSPMGAAALSTTSFPIKRERVSHL
                     LGFTNVIENSYDAVAGADYLLDVSSLLMIMMTNTSRWIHDFLLLATKEYDGITVAKPYV
                     QISSIMPQKRNPVSIEHARAITSSALGEAFTVFQMIHNTPFGDIVDTEDDLQPYLYKGI
                     EKTIRVFSIMNAVIRTMKVEEETLKSRSYKHAITITDFADVLTKNYKIPFRHAHHAAST
                     IANMSLVQKKELHELHFKDVNIYLQEKFKIHLLEKEWKEIISPEAFIQKRNVYGGPSKK
                     EMERMIQKRKESFKNEEERFETEKRRILRAEYNLNILVSNIIES"
     gene            complement(2947..4056)
                     /locus_tag="IG5_RS21450"
                     /old_locus_tag="IG5_02685"
     CDS             complement(2947..4056)
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751347.1"
                     /locus_tag="IG5_RS21450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02685"
                     /product="serine hydrolase"
                     /protein_id="WP_000751360.1"
                     /transl_table=11
                     /translation="MKKTIVCAVIVGIFVLLISGNFLVKKVWSSNNDDAQYIASFIEEH
                     KDEKNSALLVKRNDKVVYSVNPNVVLPVASTMKLIVALEYTKQVTEGKIDPASFVSIND
                     VNRYYVPNTDGGAQDRWQRYLEKTGKITEGAVTLEDVAKGMVKFSSNANAEYLMEVLGL
                     DNINRNLQSLSLPAHQPLFPIVSSLYIPGYLHKELHVPKYKIEKKLKEMTQEQYREYAM
                     IIHERLKKKGSLLQKEIPLYLEERYDKIWSDRLPAASANDYMVLLQKANHKGGLTEAEE
                     KVWASIVETDMSAKKYRKTFRHAGQKNGYTPWTVTKAVYAMDKRGNCTEIVFLANNLNE
                     DDSAEIRKHLANLHFQVLQSDKYDATFIK"
     gene            complement(4172..5119)
                     /locus_tag="IG5_RS21455"
                     /old_locus_tag="IG5_02686"
     CDS             complement(4172..5119)
                     /EC_number="3.2.2.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009879443.1"
                     /locus_tag="IG5_RS21455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02686"
                     /product="nucleoside hydrolase"
                     /protein_id="WP_073990662.1"
                     /transl_table=11
                     /translation="MELRSMKKVLFLGDPGIDDSLAIMYGLLHPDIDIVGVVTGYGNVT
                     QEKATSNAAYLLQLAGREDIPVINGAKIPLSGDITTYYPEIHGTEGLGPIRPPKNLSPN
                     IKPFCEFFDILEKYKGELIIVDAGRSTTLATAFILEKPMMKYVKEYYIMGGAFLMPGNV
                     TPVAEANFHGDPIASQLVMQNAKNVTLVPLNVTSEAIITPEMVKYITKHSKTSFNKLIE
                     PIFTYYYKAYRKLNPKIKGSPVHDVVTMMVAANPSLLDYVYRRVDVDTAGIAKGESIAD
                     FRPQPDAKALKNWVRIGWSLHYKKFLEDFVKIMT"
     misc_feature    complement(5220..5240)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 28.6"
                     /tool="antismash"
     gene            complement(5228..6661)
                     /gene="panF"
                     /locus_tag="IG5_RS21460"
                     /old_locus_tag="IG5_02687"
     CDS             complement(5228..6661)
                     /GO_function="GO:0015498 - pantothenate:sodium symporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0015887 - pantothenate transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002087740.1"
                     /locus_tag="IG5_RS21460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02687"
                     /product="sodium/pantothenate symporter"
                     /protein_id="WP_001104810.1"
                     /transl_table=11
                     /translation="MNWYVIIPMIISFIVVFLIGIYASRRVQATAHNKFLQEYFLGGRE
                     LGGLLLAMTMIATYGSASSFIGGPGIAYNMGLGWVLLSAIQVVTGYIVLTVIGKKFAII
                     ARKMEAITLIDYLKGRYNNKAVVILSALCIIIFLFSATVAQWVGGGRLIESLTGLSYTT
                     ALFLFTFSVLVYVLIGGFRAVALSDTLLGIIMLVGTTIILVATVIAGGGIEKIMQELVQ
                     INPNLITPFGADGSLTKSYVTSFWILIGIGVVGLPQISVRAMSYKNSKAMHQALIIGTV
                     VVGTIMIGMHLTGVFARVVLPGITVPDKVMPLLAMEVLPPWLAGVFLAAPMAAIMSTVN
                     SLLLLVSSSIIKDIYVNYINKDAADSTIKKGSLWITGIVGLLVYAAAIKPPDFLIWLNL
                     FSFGGLEAAFIWPIVLGLYWRKGNATGALASILVGVGSYMCIHLFYPNPFGIHTVVFPI
                     CFAFIAYIVGSMIAVKKTA"
     gene            complement(6665..6943)
                     /locus_tag="IG5_RS21465"
                     /old_locus_tag="IG5_02688"
     CDS             complement(6665..6943)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002014357.1"
                     /locus_tag="IG5_RS21465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02688"
                     /product="YhdT family protein"
                     /protein_id="WP_000800723.1"
                     /transl_table=11
                     /translation="MKNYHDDPRFRIAHREALIGLGLAIINFIIWYGFAYGLGSKNPSE
                     YTYVFGFPAWFFYSCIVGFVVMVILLSLVVRFVFQDISLDEEEKSEE"
     gene            7216..8700
                     /gene="dhaS"
                     /locus_tag="IG5_RS21470"
                     /old_locus_tag="IG5_02689"
     CDS             7216..8700
                     /EC_number="1.2.1.3"
                     /codon_start=1
                     /gene="dhaS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080288.1"
                     /locus_tag="IG5_RS21470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02689"
                     /product="aldehyde dehydrogenase DhaS"
                     /protein_id="WP_000080298.1"
                     /sec_met_domain="Aldedh (E-value: 1.1e-191, bitscore:
                     635.4, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQLAVNLHEKVEKFLQGTKKLYVNGSFVESASGKTFKTPNPATG
                     ETLAIVSEAGREDIHKAVVAARMAFDEGPWSRMSTAERSRLMYKLADLMEEHKEELAQL
                     ETLDNGKPIRETMAADIPLAIEHMRYYAGWATKIVGQTIPVSGDYFNYTRHEAVGVVGQ
                     IIPWNFPLLMAMWKMGAALATGCTIVLKPAEQTPLSALYLAELIEEAGFPKGVINIVPG
                     FGESAGQALVNHPLVDKIAFTGSTPVGKQIMRQASESLKRVTLELGGKSPNIILPDADL
                     SRAIPGALSGVMFNQGQVCSAGSRLFIPKKMYDNVMADLVLYSKKLNQGAGLSPETTIG
                     PLVSEEQQKRVMGFIEKGIEEGAEVLCGGSNPFDQGYFVSPTVFADVNDEMTIAKEEIF
                     GPVISAIPFNDIDEVIERANKSQFGLAAGVWTENVKTAHYVASKVRAGTVWVNCYNVFD
                     AASPFGGFKQSGLGREMGSYALNNYTEVKSVWLNLN"
     gene            complement(8751..9491)
                     /gene="fabG"
                     /locus_tag="IG5_RS21475"
                     /old_locus_tag="IG5_02690"
     CDS             complement(8751..9491)
                     /EC_number="1.1.1.100"
                     /GO_function="GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-166). E-value: 9.2e-20. Score:
                     63.2. Matches aSDomain:
                     nrpspksdomains_IG5_RS21475_PKS_KR.1"
                     /codon_start=1
                     /gene="fabG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395020.1"
                     /locus_tag="IG5_RS21475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02690"
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="WP_000506443.1"
                     /sec_met_domain="adh_short (E-value: 4e-41, bitscore:
                     138.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 2.6e-32, bitscore:
                     110.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFLNGKTAVVTGGAQGIGKEIARVFARLGAKVLISDVNEEKLQK
                     TTRELSDEGYEVSLYRCDVSNQNEAKSLIEYAVQKFGTLHILVNNAGITKDAMLHKMEK
                     SAWEQVLQVNLTGVFYCMQPALLYMRQQQYGRIINISSISREGNIGQANYAATKAGVVG
                     LTKTAAKEVGSFGITCNAICPGFMDTDMTKTIPDKVKEKMVGAIPVGRIGTPEDIANAA
                     AFLASEYASYITGEVLNVSGGLQV"
     aSDomain        complement(8994..9470)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IG5_RS21475_PKS_KR.1"
                     /evalue="9.20E-20"
                     /label="IG5_RS21475_PKS_KR.1"
                     /locus_tag="IG5_RS21475"
                     /protein_end="166"
                     /protein_start="7"
                     /score="63.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TAVVTGGAQGIGKEIARVFARLGAKVLISDVNEEKLQKTTRELSD
                     EGYEVSLYRCDVSNQNEAKSLIEYAVQKFGTLHILVNNAGITKDAMLHKMEKSAWEQVL
                     QVNLTGVFYCMQPALLYMRQQQYGRIINISSISREGNIGQANYAATKAGVVGLTK"
     CDS_motif       complement(9387..9464)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IG5_RS21475_0001"
                     /evalue="1.10E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="IG5_RS21475"
                     /protein_end="35"
                     /protein_start="9"
                     /score="18.1"
                     /tool="antismash"
                     /translation="VVTGGAQGIGKEIARVFARLGAKVLI"
     misc_feature    complement(9737..9754)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.88"
                     /tool="antismash"
     gene            9777..9926
                     /locus_tag="IG5_RS21480"
                     /old_locus_tag="IG5_02691"
     CDS             9777..9926
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001989403.1"
                     /locus_tag="IG5_RS21480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02691"
                     /product="YfhD family protein"
                     /protein_id="WP_001035815.1"
                     /transl_table=11
                     /translation="MNKKNFKQSKATDGIDVEFSRELADHNDLEANARANAADARQKRQ
                     STEK"
     gene            complement(10001..11854)
                     /locus_tag="IG5_RS21485"
                     /old_locus_tag="IG5_02692"
     CDS             complement(10001..11854)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000928169.1"
                     /locus_tag="IG5_RS21485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02692"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_000928185.1"
                     /sec_met_domain="T2TS (E-value: 2.2e-100, bitscore: 334.7,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLYGKVHEEIARRTTALQTMQRQDGTWRFCFEGAPLTDCHMIFL
                     LKLLGRDKEVEPFVKRLASLQTNEGTWKLYDDEMGGNLSATIQSYAALLASKKYTKEDA
                     NMKRAEMFITERGGVARAHFMTKFLLAIHGEYEYPSLFHLPTPIMFLQNDSPLSIFELS
                     SSARIHLIPMMLCLNKRFRVVKKLLPNLNHIAGGGGEWFREDQSPMFQTLLGNVKQIIS
                     YPLSLHHKGNEEVERFMKERIDENGTLYSYASASFYMIYALLALGHSIQSPMIQKAITG
                     ITSYIWKMERGNHLQNSPSTVWDTALLSYALQEARVSKESKMIQNASAYLLKKQHKKKA
                     DWSVHAPALIPGGWGFSDVNTTVPDVDDTTAVLRALAQSRGNGNVDDAWKKGTNWIKGL
                     QNNDGGWGAFEKGVTSKLLANLPIENASDMITDPSTPDITGRVLEFFGTYTQNELPEKQ
                     KQSAINWLMNEQEENGSWYGKWGICYIYGTWAVMTGLRALGITSAHPSLKRATLWLEHI
                     QHEDGGWGESCQSSVEKRFATLPFSTPSQTAWALDALISYYDKETPAIRKGISYLLANP
                     YVNEKYPTGTALPGGFYIHYHSYAHIYPLLTLAHYAKKYKK"
     gene            complement(11954..12379)
                     /locus_tag="IG5_RS21490"
                     /old_locus_tag="IG5_02693"
     CDS             complement(11954..12379)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447822.1"
                     /locus_tag="IG5_RS21490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02693"
                     /product="divergent PAP2 family protein"
                     /protein_id="WP_000447810.1"
                     /transl_table=11
                     /translation="METILHNDPLMAAVISWFIAQLTKVVFKLVKTGEFDFAKFFASGG
                     MPSSHASTVTALATGVGVVEGVESTIFAVAAIFAIIVMYDASGVRLAVSKQAKILNEFF
                     HGKQTEYKKLNELVGHTPYEVVVGALLGVIVGVGYCL"
     gene            complement(12459..13400)
                     /gene="rarD"
                     /locus_tag="IG5_RS21495"
                     /old_locus_tag="IG5_02694"
     CDS             complement(12459..13400)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene="rarD"
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016105810.1"
                     /locus_tag="IG5_RS21495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02694"
                     /product="EamA family transporter RarD"
                     /protein_id="WP_000535544.1"
                     /transl_table=11
                     /translation="MGSQSAQQKKGIIYAAGAYTMWGILPIYWKWVEEVPADEILAHRI
                     VWAFVFMLIVLAVTKRFRQFIGEFVNLFKRPKLLMSLTIASILISGNWFVYIWAVNHNH
                     VIEASLGYYINPLISILLGTVVLKEKLNFWQYVAVGLAGVGVIILTVRFGAIPWVSLSL
                     AFSFGLYGLTKKLLNYDATIGLTMETMLVTPFAFIYLVMTGVHGFGSFGAISMLSTLLL
                     IGAGIVTALPLFYFAKGAQLIPLYMVGFLQYIAPTISLILGVFVFGEHFTTTHMMAFFC
                     IWVALFVFSIAKTKFLVQKQPKFIKNKSAKVS"
     gene            complement(13493..13741)
                     /locus_tag="IG5_RS21500"
                     /old_locus_tag="IG5_02695"
     CDS             complement(13493..13741)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871327.1"
                     /locus_tag="IG5_RS21500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02695"
                     /product="DUF1294 domain-containing protein"
                     /protein_id="WP_000871326.1"
                     /transl_table=11
                     /translation="MKWIYFIIINVIAFSLMGLDKRKAKKKQWRTPESTLFLSAAAGGA
                     VGAWIGMYMFHHKTHKKKFVFGIPLLVVITVCLFFAI"
     gene            complement(13924..14325)
                     /locus_tag="IG5_RS21505"
                     /old_locus_tag="IG5_02696"
     CDS             complement(13924..14325)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000367295.1"
                     /locus_tag="IG5_RS21505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02696"
                     /product="hypothetical protein"
                     /protein_id="WP_000367294.1"
                     /transl_table=11
                     /translation="MDMKKMIETIETTKVTDVELSIHTLHQMLVKLYSEKNVTNYTELL
                     KYSLSLSINLKLNLVLKYFGVRPIVASDERMQFQEIFKCLAKQDDNGEWFLNFVSLYVG
                     LIVVLHFDEKEIERSFFDDVVVVGEGSEI"
     gene            complement(14368..14592)
                     /locus_tag="IG5_RS21510"
                     /old_locus_tag="IG5_02697"
     CDS             complement(14368..14592)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752385.1"
                     /locus_tag="IG5_RS21510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02697"
                     /product="hypothetical protein"
                     /protein_id="WP_000752368.1"
                     /transl_table=11
                     /translation="MACNIDHSIEDVMNKLESQKDFLSEILFKDLNGFLQNKHSQEILN
                     DIFHLLKKYDLVSEEEREKRNAQLLHIMN"
     gene            complement(14608..15657)
                     /locus_tag="IG5_RS21515"
                     /old_locus_tag="IG5_02698"
     CDS             complement(14608..15657)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1157: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000957504.1"
                     /locus_tag="IG5_RS21515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02698"
                     /product="P-loop NTPase"
                     /protein_id="WP_000957522.1"
                     /transl_table=11
                     /translation="MLTQEQIMNALQHVEDPELHKSVVELNMVRNVQIHGTEVKLEVVL
                     TIQGCPLKAKIQQDVEESLHAIGASKVDVTFGSMTQEERAMLTEKLKKNSRTETGMPSM
                     LRHDSGVHFITVTSGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAMMETNQ
                     KPTMIDQTAIPVVSHGVKIMSMGFFTEGNNPVMWRGPMLNKWIQNFLANTHWGDLDYLL
                     LDLPPGTGDVAIDVAAMIPQAKEIIVTTPHNVASFVASRVGVMAKHTKHEIVGIVENMA
                     YYEEQDGFKNYLFGKGGGEMLAEQLQTEVIAQIPFAKREENNDSSVYDEDSLVGEVFTA
                     LAEDIIYRG"
     misc_feature    complement(15748..15768)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.97"
                     /tool="antismash"
     gene            complement(15776..16012)
                     /gene="moaD"
                     /locus_tag="IG5_RS21520"
                     /old_locus_tag="IG5_02699"
     CDS             complement(15776..16012)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="moaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628490.1"
                     /locus_tag="IG5_RS21520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02699"
                     /product="molybdopterin converting factor subunit 1"
                     /protein_id="WP_000628491.1"
                     /transl_table=11
                     /translation="MITILLFANLREEVGSDQLIISEKKEMTVGQLNEWLKDSYHLQSL
                     DTVMVAINEEFVTNEEMIKAGDIVALIPPVSGG"
     gene            complement(16017..16481)
                     /locus_tag="IG5_RS21525"
                     /old_locus_tag="IG5_02700"
     CDS             complement(16017..16481)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531878.1"
                     /locus_tag="IG5_RS21525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02700"
                     /product="molybdenum cofactor biosynthesis protein MoaE"
                     /protein_id="WP_000531609.1"
                     /transl_table=11
                     /translation="MGQSLFEIVEKPILVEEVTNKVARREAGAITTFIGTVRELTKGKR
                     TLHLKYEAYKPMAVKQLTRIGEEINGKWPDAQVAITHRVGLLEIMDIAVVIAVSSPHRK
                     VAYEANEYAIERIKRIVPIWKKEFWEDGTMWIGDQLENTSYPEGKPKKEE"
     gene            complement(16462..17766)
                     /gene="glp"
                     /locus_tag="IG5_RS21530"
                     /old_locus_tag="IG5_02701"
     CDS             complement(16462..17766)
                     /GO_component="GO:1990586 - divisome complex [Evidence
                     IEA]"
                     /GO_function="GO:0061599 - molybdopterin molybdotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="glp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442182.1"
                     /locus_tag="IG5_RS21530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02701"
                     /product="gephyrin-like molybdotransferase Glp"
                     /protein_id="WP_000533691.1"
                     /transl_table=11
                     /translation="MGRRVPITVAEAIRKVMGFANNGLKELLPIELAYGRMLAEDLVAD
                     HDVPSFNRSPYDGFAIRAEDTNLASYETPIVFEVVGEIGAGSLFDEKVGSFQAVRIMTG
                     AQIPNDCDAVVMLELTRQYEDNGNDYMEVKRSFKTGDNISFQGEDARKGTVLAKKGSYI
                     NPGISALLATFGYSEVPVAKKPVIGLLATGSELLDVNESLEPGKIRNSNTYMILSQIRR
                     VGGRVKYFGKFSDDFDTCFTAVKDALSQVDMLITTGGVSVGDYDYLPAIYGRLGASVLF
                     NKVAMRPGSVTTVAQLNGKLLFGLSGNPSACYVGFELFVRPCIRAYMFSEKAHLKREKA
                     LLGKDLLKPNPFTRFVRAKLTCNEGQLIAYPSGFDKSSSVSSLAESNAFIVLPGGTRGY
                     KKEMFVDVLLLEDNEGSEWLWTFYKRGVSNGAITI"
     gene            complement(17785..18801)
                     /locus_tag="IG5_RS21535"
                     /old_locus_tag="IG5_02702"
     CDS             complement(17785..18801)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016103071.1"
                     /locus_tag="IG5_RS21535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02702"
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="WP_000392759.1"
                     /sec_met_domain="ThiF (E-value: 1.4e-59, bitscore: 199.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEERYSRQQLFKPIGSKGQEKIRNKHVLIVGAGALGSTSAESLVR
                     AGIGKLTIIDRDYVEWSNLQRQQLYSEEDARGKIPKAIAAKKRLEQINSEVQIHAFIMD
                     ASVENMEGPLENVDVIIDATDNFDIRFIINDLSQKHNIPWVYGSCVGSYGMSYTIIPQK
                     MPCLHCVLKNVPVIGVTCDTAGIISPAVQIVAAYQVAEALKILVEDYSVIRKTFFMFDI
                     WSNQNHFIKLGKIKTDDCPSCGLNRAYPYLSYENQTKVAVLCGRNTVQIRSIENRQYNF
                     DDVEKVLKKLGEVERNPYLLSCQLEDYRVVIFQDGRVFIHGTNEIPKAKQLYYRLFG"
     gene            complement(18826..19605)
                     /locus_tag="IG5_RS21540"
                     /old_locus_tag="IG5_02703"
     CDS             complement(18826..19605)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014894720.1"
                     /locus_tag="IG5_RS21540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02703"
                     /product="formate/nitrite transporter family protein"
                     /protein_id="WP_000863999.1"
                     /transl_table=11
                     /translation="MAFHKPEQIAELVIEAGVQKVSQTLPAMLILGFLGGAFISLGFLL
                     NIRVLGNLPEHWGSLVNVLGGAVFPIGLMLVVLAGGELITGNMMSLSMALYAKKITLIS
                     VLNNWAWITVMNFVGAIFVAYCFGHLGGLTEGDYLNKTLAIAEGKLHESFGRTLILAIG
                     CNWLVCLALWLAYGTSDFVGKIIGIWIPIMAFVVIGFQQVVANMFVISAVIFAGHLTWL
                     DLAKNFVPVFIGNVIGGAGFVGFAYFACYQKQDSNVK"
     gene            complement(19797..20813)
                     /gene="moaA"
                     /locus_tag="IG5_RS21545"
                     /old_locus_tag="IG5_02704"
     CDS             complement(19797..20813)
                     /EC_number="4.1.99.22"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="moaA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016111392.1"
                     /locus_tag="IG5_RS21545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02704"
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="WP_000836454.1"
                     /sec_met_domain="PF04055 (E-value: 9.1e-29, bitscore: 98.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 9.9e-10, bitscore: 36.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 4.8e-08, bitscore: 30.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSITLDKLHRPLKDLRISVTDRCNFRCRYCMPEEIFGPDYSFLS
                     NDKILSFDEIERITRIFVSLGVRKLRITGGEPLLRRGLPELIERLNKIDGVEDIGLTTN
                     GSLLKKFAPDLYKAGLSRVTVSLDSLEEERFFYLNGNRSKVQRVLEGIQAAAEVGMKIK
                     INMVVQKGKNEQDILQMAQYFKENKHILRFIEYMDVGNYNGWELGEVISKQEIVNTIRE
                     VMPLERIEANYPGEVATRYRYIGSDEEIGIISSVTDSFCSSCTRARISAEGKLYTCLFA
                     SKGNDLRALLRSGDTDEEITAVIHDIWNNREDRYSDERLSHTNKKTMPKIEMSHIGG"
     gene            complement(20834..21631)
                     /gene="fdhD"
                     /locus_tag="IG5_RS21550"
                     /old_locus_tag="IG5_02705"
     CDS             complement(20834..21631)
                     /GO_component="GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /GO_process="GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fdhD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802668.1"
                     /locus_tag="IG5_RS21550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_02705"
                     /product="formate dehydrogenase accessory sulfurtransferase
                     FdhD"
                     /protein_id="WP_000802702.1"
                     /transl_table=11
                     /translation="MKPIQVEREVFRYEQGVFKHIEDSIVTEFPVTIKMNGQEFVTMVS
                     TPEYIEDMVIGFLASEGIIRKYEDIDHIWVQEKEGFVHVTTTKINPYYEQMQNKRYITS
                     CCGMSRQGFVFANDALSVKKMNGVHVKVAVEDCFRLMNEMQQSADTFRHTGGVHNAALC
                     DVNGIILGRMDIGRHNALDKIYGYCLKNNISIKDKIIVFSGRISSEILLKVAKIGCEII
                     LSKSAPTELALQLAEELGITTIGFIRNQSLNIYTHPERVLNIK"
ORIGIN
        1 gaaagctggt gtgaatatgt ttacacaatg cgtagcgact gaagaagagg aaaaagaata
       61 tccagtaaaa atcgtcgctt ttgcacctgg tgttgtggat acaaatatgc aagtacaaat
      121 tcgtgaaaca aataaagaag acttcacaaa tttagaccga ttcatcacac taaaagaaga
      181 aggaaagcta ttatcacctg aatatgtggc aaaagctatt cgtaacttac tagaaactga
      241 gaacttcccg caaggcgaag ttattagaat tgatgaataa taaaaaggcg tgctaaaata
      301 gcacgccttt ttattctact tctctaaaaa tatgagcaca gactccgcaa tttgttcata
      361 accaatttct tgataaattt tattagatgt cggattggct aaatcagtat atagtgtagt
      421 cgtcttgtac ccttcgtcta acatacgttg actgagtgcc gctacacaat tagatgcgta
      481 cccttttttt cgtgcttctt tcggggtata aacgaaattt actgttatat tatttgtagt
      541 tggtctcgtt tttgcagcta cagaaacgag tttcccatct acttctagac caaatagacg
      601 attattagtg attaatgtat gtgcggtttg ttccgcttct tctttcgtag ttgggagctt
      661 cacatcttca caaaattgat atatccattt ttctattaat ggcaactcat cattagttat
      721 ttctcgaaaa attccatcct cgttccactt cttcttaatt tgttgtaatg catatacacc
      781 ttgtttcatt acaacattcg ttttcttatt ttctaacacc gcaagctctt cagctaattt
      841 ctgtacaatt tccttattac cgatcaatcc aggaatgtcc ggatatactt tcgataactc
      901 ttttgcaagt ttcactatat ctacttccga attttcagaa gttgcaacaa tcatttgtat
      961 cttctcttct gtttgaagaa atacaactgt aatttcttct cctcgtttcg ctacccccat
     1021 aaacgtcggt tcttgagcta cttgtaatat acctaacatt aaattatttt cctgctcatt
     1081 cttttctaaa aatggtgtaa catcttcttt aaaatgaaga atctctttat atacgtgtaa
     1141 ttgaatcatc gacaatctct tctctccatt tatattttaa ttaagtattg gcgattaatt
     1201 cattaaatcc ttcttttacg attcgataat atttgaaact aatatgttca aattatattc
     1261 agctcgtaat attctccgtt tttccgtttc aaatcgctct tcttcatttt taaatgactc
     1321 tttacgcttt tgaatcattc gttccatctc ttttttactc ggtcctccgt atacatttct
     1381 tttttgaata aaagcttctg gcgatataat ttctttccac tctttttcca ataaatgtat
     1441 tttaaatttt tcttgtaagt atatatttac atctttgaaa tgtaattcat gaagctcctt
     1501 tttctgcacc aatgacatat tagcaatcgt acttgctgca tgatgagcat gccgaaatgg
     1561 aattttatag ttttttgtta aaacatctgc aaaatcagtt atcgttattg catgtttata
     1621 ggaacgactt tttaacgttt cttcttctac tttcatcgtt cgaatgactg cattcataat
     1681 agaaaatacg cgaatcgtct tttcgattcc tttatataaa tacggctgta agtcatcttc
     1741 cgtatcgaca atatccccaa atggtgtatt atgaatcatt tgaaatactg taaatgcttc
     1801 tcctaaagcg ctactcgtaa tagcacgagc atgctcaatt gaaactggat ttcgtttttg
     1861 tggcataata ctactaattt gcacatatgg cttcgcaaca gtaataccat catattcttt
     1921 cgtcgctaat aataagaagt catgaatcca tctactcgta tttgtcatca ttatcataag
     1981 taacgagcta acatctaata aataatccgc tccagcgaca gcatcatatg agttctcaat
     2041 tacatttgta aatccaagta aatgagaaac tcgttctcgt ttaatcggaa aacttgttgt
     2101 tgaaagtgca gctgccccca tcggagactg atttaaaatt tggtacgttt ttttcattcg
     2161 ttctaagtct ctttgcatcg tatcataaat tgctaacata taatgaccaa acgttgttgg
     2221 ctgtgctggt tgtgtatgtg tataagctgg cataattgtt cccttatgat catcagcaag
     2281 ttgcaatata ctttcttgca ataataaatg gtgttccatt aatcgtaata catatcgtct
     2341 taagctcata cgatacatcg ttactcccat atcatttcta cttcgaccga tatgcatatt
     2401 acttacaaaa tcacactttg cttcctgaga aattaaatgt tcaactaaaa aaaagagatc
     2461 ttcatgttgt tctgtatatc gcaattgatc tttgggcatt ccttctacct tttttagtgc
     2521 ttttaatata actgtagctt cttctttttt tattaaactt tcttcagtca gcatcataat
     2581 atgcgcttta tgcacttgaa acatatcttt taataagtgg ttatactgaa aattaaatac
     2641 atgttgtaat acacaatcca catatgtttt cccagggaaa tcagcgcctt cattctttat
     2701 aaattcttct ttactctgtt tcatcacctt ttcccctttc acctaagtat tactacccat
     2761 catacccaga gatagtaaaa aagtgcttat acataaagtg aaactttaat tagcccttac
     2821 caatcggcct tttacaggca attgtactcc cacctaactc tctcgcattc gcccaatttt
     2881 gagatgggag tcttactgtc cacaaatagc gggacaaaaa taaactcggt gctttatgca
     2941 ccgagtttat ttaataaaag tcgcatcata cttatcactt tgcaacactt ggaaatgtaa
     3001 atttgctaaa tgtttacgta tttctgcact gtcatcttca tttaaattat tcgctaagaa
     3061 tacaatttct gtacagttcc cgcgcttatc catagcataa accgcttttg taaccgtcca
     3121 tggcgtatac ccattctttt gtcctgcgtg tctgaatgtt ttacgatatt tcttggcact
     3181 catatctgtt tcaacgatac tcgcccacac tttttcttca gcttctgtca ggccaccttt
     3241 atggtttgcc ttttgcagca ataccatata atcgtttgcg gacgcagctg gtaatctatc
     3301 tgaccaaatt ttatcataac gttcctctaa ataaagagga atttctttct gtaataatga
     3361 ccccttcttt tttaagcgct catgaataat catcgcatat tcacgatatt gctcttgagt
     3421 catttctttt aattttttct ctattttata ttttggaaca tgtaattctt tatgcaaata
     3481 tcctgggata tataaagatg aaacaatcgg aaatagtggt tgatgtgcag ggagcgataa
     3541 actttgtaaa tttcgattaa tattatctaa tcctaacact tccattaaat attccgcatt
     3601 agcattcgaa ctaaacttaa ccattccttt tgccacgtct tctaaagtaa cggctccttc
     3661 agttatcttg cctgtcttct ccaaatacct ttgccatcta tcttgtgcac caccatctgt
     3721 attcggtaca taatatcgat tgacatcatt aattgaaacg aaactagccg ggtcaatttt
     3781 cccttctgta acttgtttcg tatattcaag cgccacaatt aatttcatcg tactagcaac
     3841 tggcaataca acatttggat ttacagaata aacaacttta tcatttctct ttactagaag
     3901 cgcactattt ttttcatctt tatgttcttc aataaaagat gcaatatact gtgcatcatc
     3961 attatttgaa ctccatactt ttttcactaa aaagttaccc gatattagca aaacgaaaat
     4021 acccacaatt actgcgcata ctatagtttt tttcaagtaa aattcctctc ctattgtata
     4081 actcttctct ctatctttaa aaaacaaaat aatggagatg gtcatttaaa taaccatctc
     4141 cattatttta acttgtatac tcctattatg tctacgtcat gattttcaca aaatcctcaa
     4201 gaaatttttt ataatgtaat gaccaaccaa ttcgtaccca atttttcaag gcttttgcat
     4261 caggttgagg acggaaatct gcaatacttt ctccttttgc aattccagct gtatctacat
     4321 cgacacgacg atatacataa tctaaaaggg atggatttgc cgcaaccatc attgtaacga
     4381 cgtcatgtac tggacttcct tttattttcg gatttaactt tctataagct ttataataat
     4441 acgtaaatat cggctcgatt aacttattaa aactcgtttt agaatgtttc gtaatatatt
     4501 ttaccatctc tggcgttata attgcctcgg atgtaacatt aagcggcact aatgttacat
     4561 tcttcgcatt ttgcataact aactgtgacg caatcggatc gccatgaaaa ttcgcctccg
     4621 ccactggtgt aacattgcca ggcattaaaa aagcaccgcc cattatataa tattctttta
     4681 catatttcat catcggcttt tctaaaataa acgctgtcgc taatgtcgtt gacctaccag
     4741 catcaacaat gattaattct cctttatatt tttcaagaat atcgaaaaac tcacaaaaag
     4801 gctttatatt tggagaaagg tttttcggag gacgaattgg ccctaaacct tccgtcccgt
     4861 gaatttctgg ataatacgtt gtaatatctc cagataaagg gattttcgca ccattaataa
     4921 ctggtatatc ttccctacct gctaactgta ataaatacgc tgcattactt gtcgcttttt
     4981 cttgtgttac attcccatat ccagttacta caccaacaat atcaatatca ggatgcaaca
     5041 atccatacat aattgctaaa gagtcatcta ttcccgggtc tcctaaaaat aacacttttt
     5101 tcatcgacct caactccatc ccctcagttg ttattaattt atgaatagcc ctacatatac
     5161 agaataaaaa aaatgaaatt tatataaaaa aaacgcagtc ctatacggac tacgttcttc
     5221 atctagccta tgctgttttt ttcacagcaa tcatacttcc cactatgtaa gcgataaacg
     5281 caaagcaaat tgggaagaca actgtatgta taccgaacgg atttgggtag aaaagatgaa
     5341 tacacatata tgagcctacc ccaactaaaa tggaagcaag cgctccagtt gcattccctt
     5401 ttctccaata taaccctaag acgatcggcc aaatgaatgc tgcttctaat ccaccgaaag
     5461 aaaataaatt taaccatatt aaaaaatctg gtggtttaat cgccgctgca taaacgagca
     5521 gtcctacaat acccgtaatc cacaaacttc ctttttttat cgtactgtct gctgcatctt
     5581 tatttatgta atttacatat atatctttaa taatcgatga acttacaagt aacaatagcg
     5641 aatttactgt agacataatc gctgccattg gtgccgctaa gaaaacacca gctagccaag
     5701 gcggcaacac ttccatcgcg agtagcggca tgactttatc tggtaccgtt ataccaggaa
     5761 gtactactcg tgcaaataca cccgttaaat gcatcccgat cataattgta ccaacgacaa
     5821 ccgttccaat gattagagct tgatgcatag cttttgaatt tttataagac atagcacgca
     5881 cactaatttg tggtaaaccg acaacgccaa ttccaattaa aatccaaaac gatgtaacat
     5941 atgatttcgt taaactacca tctgctccga atggtgtaat taaattcgga ttgatttgaa
     6001 caagttcctg cataatcttt tcaattccac caccagcaat aacagtagca actaaaatga
     6061 ttgtcgttcc aactaacata atgataccta ataacgtatc tgataacgca actgcgcgga
     6121 acccaccaat taatacgtac acaagtacag aaaaagtaaa taaaaatagt gctgttgtat
     6181 aagatagacc tgttagcgac tcaattaatc gtccaccgcc gacccactgg gctactgttg
     6241 ctgaaaataa aaagataata atacataacg ccgaaagtat aacaaccgct ttattattgt
     6301 atcttccttt taaataatcg ataagcgtaa ttgcttccat cttcctagca ataattgcaa
     6361 actttttacc gataactgtt aaaacgatat accctgttac aacttgaatc gcagataata
     6421 atacccatcc aagtcccata ttgtaagcaa taccagggcc accaatgaaa ctacttgcac
     6481 taccgtacgt agcaatcatt gtcatcgcta ataataaacc gccaagctca cgtccaccaa
     6541 gaaaatattc ttgcaaaaat ttattatgag cagtcgcttg cacgcgtctt gaagcatata
     6601 taccaattaa aaatacaacg ataaacgaaa ttatcattgg aatgattaca taccaattca
     6661 tctattattc ctcacttttt tcttcctcat cgagtgaaat atcttgaaat acaaaacgaa
     6721 caactaaact aagcaaaata accattacga caaatccaac aatacaacta taaaaaaacc
     6781 atgctggaaa accgaataca tatgtatatt cacttggatt tttactacca agcccataag
     6841 caaatccgta ccatattata aaattgataa tagcaagtcc aagaccaatt aacgcttctc
     6901 tatgggcgat tcgaaagcgt ggatcatcat gataattctt cattttctcc ctcctctcac
     6961 gatgtattat tgtaccattg ttcttctagt ttttcctact agaaagcaaa aacaagcagg
     7021 attttttata attatataga agactctctt acattacata ttttttacaa ttgtaacaca
     7081 aatgaaattt gaattttcag taattgttaa ttatgatttt aattagaggc tttccatcta
     7141 gttcctacat ccttgatttc ggaataaacg ccgtctcgta ctgcgtttac attatatttt
     7201 caagggggtt atacaatgag tcaactagct gtaaatcttc atgaaaaggt agaaaagttt
     7261 cttcaaggca cgaaaaagtt atatgtgaat ggatctttcg ttgaaagcgc ttccggtaaa
     7321 acgtttaaaa cgcctaaccc tgcaactggc gaaacgcttg ccatcgtttc tgaagctggt
     7381 cgcgaagata ttcataaagc tgtagtcgca gctcgcatgg cttttgacga aggtccttgg
     7441 tctcgcatga gcactgctga acgaagccgc cttatgtaca agcttgccga tttaatggaa
     7501 gaacataaag aagagcttgc acagctcgaa acgttagata acggaaagcc aatccgtgaa
     7561 acaatggcag cagacatacc acttgcaatt gagcatatgc gctattatgc tggctgggcg
     7621 acgaaaatcg ttggtcaaac aattcctgtt tccggtgatt actttaacta tacacgccat
     7681 gaagctgttg gtgtcgttgg tcaaattatc ccttggaact tcccgcttct tatggcaatg
     7741 tggaaaatgg gagcggcgct tgctacagga tgtacaatcg ttttaaaacc tgcagaacaa
     7801 actccactat ccgctctata cttagctgaa ttaattgaag aagctggatt cccgaaaggt
     7861 gttattaata tcgttcctgg attcggtgaa tcagctggac aagctctcgt taatcatcca
     7921 ctcgttgata aaattgcatt tactggttct actccagttg gcaaacaaat tatgagacaa
     7981 gcatccgaat cattaaaacg tgttacttta gaacttggtg gtaaatcacc aaatattatt
     8041 ttaccagacg ccgacttatc tcgcgctatt cctggtgcac tttctggtgt tatgtttaac
     8101 caaggacaag tatgctctgc tggatcacgc ttatttattc cgaagaaaat gtatgataat
     8161 gtcatggctg atctcgtcct ttattctaaa aaattaaatc aaggtgctgg tctaagtcca
     8221 gaaactacaa tcggtcctct cgtttccgaa gaacaacaaa aacgtgtaat gggcttcatt
     8281 gaaaaaggga ttgaagaagg cgctgaagta ctttgtggag gaagtaatcc atttgatcaa
     8341 ggctacttcg tttctcctac agtattcgcc gacgtcaatg atgagatgac aatcgcaaaa
     8401 gaagaaattt tcggtccagt tatttctgca ataccgttta acgatattga tgaagtaatt
     8461 gaacgtgcga ataaatcaca atttggcttg gcagctggtg tatggacaga aaatgttaag
     8521 acagcacact atgttgcaag taaagtacgc gcaggtacag tatgggtaaa ctgttataac
     8581 gtctttgatg cagcatctcc atttggagga tttaaacaat ctggtcttgg ccgtgaaatg
     8641 ggatcttacg cattaaataa ctatacagaa gtgaagagcg tttggttaaa cttaaattaa
     8701 atcgaaagaa cctgatccac tcggtcaggt tcttttcatt atgtattcct ttaaacttgc
     8761 agccctccgc tcacatttaa tacttcccct gtaatatagg atgcgtattc tgacgctaaa
     8821 aaggccgccg cgttcgcaat atcttctggc gttccaattc taccaaccgg aattgctcca
     8881 accatttttt cttttacttt atctggtatt gtttttgtca tatccgtatc cataaatcct
     8941 ggacaaattg cattacaagt aataccgaag cttccaactt ctttcgctgc tgttttcgtt
     9001 aaaccgacaa cgccagcttt cgttgccgca taatttgctt gtccaatatt cccttctcta
     9061 cttattgaag aaatattaat aatgcgccca tattgttgtt gtctcatata aagaagagct
     9121 ggctgcatac aataaaaaac gccagttaag tttacttgta atacttgttc ccaagctgat
     9181 ttctccattt tatgtaacat tgcatctttt gtaattccag cgttatttac taaaatatgc
     9241 agtgtcccaa atttttgaac tgcatactca attaatgatt tcgcttcatt ttgattactt
     9301 acatcacatc gatataagct tacttcatat ccttcgtccg ataattcacg tgtcgttttt
     9361 tgtagttttt cttcatttac atcactaatt aaaactttag ccccaagcct agcaaaaact
     9421 cgtgcaattt cttttccaat tccttgggcg ccacctgtta caacagctgt tttcccattt
     9481 aaaaatccca tccctatccc ccatttctat tacttatact gtatatttcg gctttttgct
     9541 ttccaaatcc tctttgtata aaaaagtcta tttgtgtcaa actaactttg caacgtcgca
     9601 taaagtgaaa ctttaatcag tgggaagttt gttcatcccc cactgattat cagccctcac
     9661 caatcgggca tttacgggca gttaatctcc cacctagctt ctttgttcca tctgaatttt
     9721 gaggtgggag ttttactacc cgctatgcgg gataaagtgc aaggagattg tgtcgaatga
     9781 acaaaaaaaa tttcaaacaa agcaaagcca ctgatggtat tgatgttgag ttctctcgtg
     9841 aactcgctga ccacaacgac ttagaagcaa acgcacgtgc aaatgccgct gatgcacgtc
     9901 aaaaacgcca gtcaacagaa aaataagggg aaatcataac cttattcttt tcaacaggga
     9961 cctactaccc aacaaaataa accgagaaac atctctcggt ttatttttta tatttttttg
    10021 cataatgcgc caaagtaagt aacggatata tatgagcgta gctatggtaa tgaatataaa
    10081 acccacctgg taaagctgtt ccagtaggat atttttcatt tacataagga ttcgcaagca
    10141 aatatgaaat accttttcga atagctggtg tttctttatc atagtaagaa ataagagcat
    10201 ctaaagccca tgctgtttgc gatggtgtac taaatggtaa agtagcaaat cttttttcca
    10261 cactactttg acaagattct ccccagccac catcttcatg ctgtatatgt tcaagccata
    10321 aagttgctcg ttttaaagaa gggtgagcag aagtaattcc taacgcccgt aagccagtca
    10381 tcactgccca tgtaccatat atataacaaa tgccccattt tccataccac gatccatttt
    10441 cctcctgttc attcattaac cagttgattg cactttgttt ttgtttctcg ggcaattcat
    10501 tttgcgtata tgtcccgaaa aactctaaca ctctgcctgt aatatctggt gtagaaggat
    10561 ccgtaatcat atcgcttgcg ttttcgattg gtaaattcgc taataacttg cttgtcacgc
    10621 ctttttcaaa tgctccccaa ccaccatcat tattttgtaa tcctttaatc caattcgtcc
    10681 ctttcttcca agcatcatcc acatttccgt tccctctact ttgtgccaat gctcttaaca
    10741 cagctgttgt atcatcaaca tcaggaactg tcgtattcac atcagaaaaa ccccaaccgc
    10801 ccggaataag cgcgggcgca tgcacactcc aatcagcttt tttcttatgt tgttttttta
    10861 ataaatatgc tgacgcattt tgaatcattt tactttcttt cgaaacacga gcctcttgca
    10921 acgcataact aagtaatgct gtatcccata cagttgacgg ggaattttgt aaatggttcc
    10981 ctctttccat cttccatata taagatgtta tccccgttat agccttttga atcattggcg
    11041 attgaataga atgtcctagc gcaagtaaag cataaatcat ataaaacgaa gcacttgcgt
    11101 aactatataa cgtcccattc tcatcgatac gctctttcat aaaacgttct acttcctcat
    11161 ttcctttatg atgtaaggaa agcggataag atataatttg tttcacatta cctaataatg
    11221 tttgaaacat tggagattgg tcctcccgaa accattctcc gcccccgccc gcaatatgat
    11281 ttaaattagg cagtaacttt ttcactacac gaaacctttt atttaaacac aacatcatcg
    11341 gaattaaatg gatacgtgcc gaactactta attcaaatat actgagtggg gaatcatttt
    11401 gcagaaacat aatcggtgtt ggcaaatgaa agagcgaagg atattcatac tctccatgaa
    11461 ttgctaataa aaacttcgtc ataaaatgag cacgcgccac tcccccacgt tctgtaataa
    11521 acatttccgc tcgcttcata ttcgcatctt cttttgtata ctttttcgaa gcaagtaggg
    11581 cagcataaga ttgaatggta gcagataaat tgccccccat ttcatcatca tacaatttcc
    11641 atgtcccttc attcgtttgg agtgaagcta atctttttac aaatggttct acctctttat
    11701 ctctacctaa taattttaat aaaaatatca tatggcaatc agttaatggt gctccttcaa
    11761 aacagaatct ccacgtacca tcttgccttt gcatcgtttg aagtgcagtt gtccttctcg
    11821 ctatttcttc atgcactttt ccatataata acaaggcatt cacctaccct ttcgaaatcc
    11881 gtataacgat attcaaaaaa gcaaccgaat atgtgtaaaa acaaagaaaa gcagaacaca
    11941 tattatgttc tgctcataag caatatccca ctccgacaat aacccctaat aaagcaccga
    12001 ctactacttc atacggtgta tgtccgacaa gctcatttaa cttcttatat tctgtttgtt
    12061 taccatgaaa aaattcattc aatattttcg cctgtttact taccgcaagc cttactcctg
    12121 aagcgtcata cataacaatg attgcaaaga ttgcagccac tgcaaatatg gtactttcca
    12181 caccttccac aactccaaca cctgtcgcaa gcgctgtaac agttgaagca tgagaacttg
    12241 gcatcccacc tgaagcaaaa aattttgcaa aatcaaattc acccgtttta actaatttaa
    12301 agactacttt tgttaactgt gctataaacc acgaaattac agcagccatc agcggatcat
    12361 tatgtaaaat tgtttccatg ttctcagctc cctactagct ataatggaaa ttctatatag
    12421 tatcagtata aagaaaaatg cgtagaaaat actacgcatt atgatacttt tgctgattta
    12481 ttttttataa atttcggttg tttctgcact aaaaattttg tcttcgctat tgaaaataca
    12541 aataaagcaa cccatataca gaaaaatgcc atcatatgag tagttgtaaa atgttcacca
    12601 aatacaaata cacctaaaat taaactaatc gttggcgcaa tatattgtaa aaagcctacc
    12661 atataaagcg gaataagttg tgctcctttt gcaaaataaa atagtggtag cgctgtaaca
    12721 atacctgctc ctattaaaag taacgtcgat agcattgaaa tagctccaaa tgaaccgaaa
    12781 ccatgtaccc ctgtcataac gagataaatg aacgcaaacg gcgtcactaa catcgtttcc
    12841 atcgtaagcc caatcgtcgc atcatagttt aacaattttt ttgttaatcc gtataatcca
    12901 aatgaaaagg caagtgataa agaaacccac gggatagccc cgaaacgtac tgttaaaatg
    12961 ataaccccta ctccagctaa acctactgca acatattgcc aaaagtttaa cttttccttt
    13021 aatacgactg taccaagtaa aatactaata agtggattaa tataataccc aagactcgct
    13081 tcaatgacat gattatgatt aacggcccat atgtagacaa accagttccc actaatcaaa
    13141 attgaagcaa ttgttaatga cattaataat ttaggtcgtt taaaaagatt cacaaattcc
    13201 ccaataaact ggcgaaacct cttcgtaaca gctaatacga ttaacataaa aacgaacgcc
    13261 caaacaatgc ggtgtgctaa tatttcatct gctggaactt cctcaaccca tttccaataa
    13321 atcggtagga ttccccacat cgtataagca ccagccgcat atataatccc ttttttttgc
    13381 tgtgctgatt gactccccat cttccttttt ctcctcttct cattttttct ccattatacg
    13441 gtttcttatg ctcactttac caataatcaa tctgtaattc tttcgacatt tctcatatag
    13501 cgaaaaataa acataccgtt attacaacaa gtaacggtat gccgaaaaca aatttctttt
    13561 tatgcgtttt atggtgaaac atatacatac cgatccaagc tccaaccgct cctccagctg
    13621 ccgctgataa aaacaacgtg ctttctggcg ttctccactg tttcttcttg gcttttcgtt
    13681 tatcaagccc cataaggcta aaagctataa cattaataat aataaaataa atccatttca
    13741 tcgctttctc tccctatgaa aaattcgctt aatggtaaca tgaaaaaacg atagaaacaa
    13801 ctgaagaaca ctttttagca aactagtttc attcctttat tttaattgat tatctttaca
    13861 tttatataat caatataaag cgcgattaca actattaaaa agaaagatgt tatgaacaga
    13921 actttatatt tcacttcctt cacccaccac aaccacatca tcaaaaaaac ttctctcaat
    13981 ctctttctca tcaaaatgaa gaacaacaat taaccctaca tataaagaaa cgaaattcaa
    14041 aaaccattcc ccattatcat cttgcttagc taaacattta aatatctctt gaaattgcat
    14101 acgttcatca gaagcaacga tcggacgcac accaaaatat ttcaacacaa gatttaactt
    14161 aagatttata gataaagaca aactatattt taagagctct gtataatttg taacattttt
    14221 ttcgctatac agtttcacaa gcatttgatg taaagtatga atcgataatt ctacgtcagt
    14281 cacttttgtt gtttctatcg tttcaatcat ctttttcata tccatcacat tcaccccttc
    14341 tgaaaaaact ttaaagccag agagtattta attcataatg tgcaataatt gtgcatttct
    14401 cttctctcgt tcttcttcac tgactaagtc atactttttt aataaatgaa agatgtcgtt
    14461 taatatttcc tgtgaatgtt tattttgcaa aaatccattc aaatctttga aaagaatttc
    14521 agataaaaaa tccttttgac tttcaagctt attcattaca tcttcaatag aatgatcaat
    14581 attacatgcc atattaaact tcctcctcta tcctctataa ataatatctt ctgctaatgc
    14641 agtaaatact tctccaacga gagagtcttc atcatataca gatgaatcgt tattttcttc
    14701 acgttttgca aaaggtattt gtgcaattac ttccgtttgc aattgttctg ctaacatttc
    14761 gccgccccct tttccgaaga gataattttt aaatccatct tgctcttcgt aataagccat
    14821 attttccaca attcctacaa tctcgtgttt tgtatgtttt gccattacac ctactctaga
    14881 agctacaaat gaagctacat tgtgcggcgt tgtaacgata atttctttcg cttgtgggat
    14941 catcgctgca acatcaatgg caacatctcc tgtaccaggt ggtaaatcga gaagtaaata
    15001 atctaaatct ccccagtgtg tattcgcaag gaagttttga atccatttat ttaacatcgg
    15061 tccacgccac atgactggat tatttccttc tgtaaaaaat cccattgaca taattttaac
    15121 accatgacta acgactggaa ttgctgtttg atcaatcatt gttggttttt gattcgtttc
    15181 catcatagcc ggaatgctaa aaccatatat gtctgcatct aaaatcccaa cctttttacc
    15241 cattctagct aaggcagtag caagattaat tgtcaccgtt gattttccga ctccgccttt
    15301 cccactcgtt acagtaataa aatgtacacc tgaatcatga cggagcatgc ttggcatacc
    15361 tgtttctgtt ctactatttt tctttaattt ttctgttagc atagctcttt cttcttgtgt
    15421 catcgaacca aatgttacat ccactttaga tgcaccaatt gcgtgaaggg actcttccac
    15481 atcttgttga attttcgcct ttaacggaca accttgaatg gttaacacta cttcaagctt
    15541 aacctctgtt ccatgtattt gtacatttct aaccatattt aattctacaa cacttttgtg
    15601 taactctgga tcctctacat gttgtaatgc gttcattatt tgttcttgag taagcataga
    15661 gctcatccct tctcttattc taatttatat atagcatctt cttattactt caactgatga
    15721 aagtttccat ctatttttta atgtctttaa tagtcatcgt tgcgagaaag cattattatc
    15781 ccccacttac aggcgggatt aatgcgacga tatctccagc ttttatcatc tcttcattcg
    15841 ttacaaactc ttcattaatt gcaaccatta ctgtatccaa agattgcaaa tgataactat
    15901 ctttcaacca ttcatttaat tgtccaacag tcatttcttt tttttctgaa attattaatt
    15961 gatccgatcc gacttcctca cgcaaatttg caaacagtaa aattgtaatc attttctcat
    16021 tcttccttct tcggttttcc ttctggatat gatgtatttt caagttgatc tccaatccac
    16081 atcgttccat cttcccaaaa ttcttttttc caaattggaa cgatgcgttt tatgcgttca
    16141 atcgcgtact cattcgcttc ataagctact ttacgatgcg gtgatgaaac tgcaataact
    16201 accgcaatat ccattatttc cagcagccct acacggtgcg taatggctac ttgtgcgtcc
    16261 ggccatttcc cgttaatttc ctcaccaatt cttgtaagtt gttttactgc catcggttta
    16321 tatgcttcat actttaaatg tagcgttcgt tttccttttg ttaattctct caccgtacca
    16381 ataaatgttg taatcgcacc cgcttctctt cttgcgactt tattcgttac ttcttccact
    16441 aaaattggtt tttctacaat ctcaaatagt gattgcccca ttagaaacac ctctcttata
    16501 aaatgtccaa agccattcac taccttcgtt atcttctaat aaaagaacat cgacaaacat
    16561 ttctttttta tatcctcttg tcccgcctgg caatacgata aaagcgttcg attctgctaa
    16621 tgaagaaacc gagctagact tatcaaatcc tgatggatat gcaattaatt gcccttcatt
    16681 acatgtcagt tttgctcgta caaatcttgt aaatggattt ggtttcagaa gatcttttcc
    16741 taataatgct ttttctcttt tcaaatgcgc tttttcacta aacatatacg cacgaataca
    16801 tggtcttaca aacaactcaa atcctacata acatgctgat ggatttcctg ataaaccaaa
    16861 taatagcttg ccatttaatt gtgctacagt cgttacactt cctggtcgca ttgcaacctt
    16921 attgaaaaga acggatgcac ctaaccttcc atatatagct ggtaaataat cgtaatctcc
    16981 tactgataca ccgcccgttg taatgagcat atctacttga cttaacgcat ctttcacagc
    17041 tgtaaaacac gtatcaaaat catcactaaa cttcccaaag tattttactc ttccgcccac
    17101 tcttcgaatt tgagacagta tcatgtacgt attactattt cgaattttcc ctggctctaa
    17161 cgactcattt acatcaagta attcactacc agtcgctaat agtccaatta ctggcttttt
    17221 cgcaactggc acttcactat aaccgaatgt agcaagaaga gctgaaatac ctggattaat
    17281 gtacgatcct ttctttgcaa gcaccgttcc tttacgagca tcttcacctt gaaaagaaat
    17341 attatcaccc gttttgaatg agcgtttcac ttccatataa tcgttcccat tatcctcata
    17401 ttgacgagtc agttctaaca taacaaccgc atcacaatca tttggaattt gtgctcctgt
    17461 cataattcga actgcttgaa acgaacctac tttctcatcg aatagtgatc ctgcaccaat
    17521 ttcaccaact acttcaaata caattggcgt ttcataactt gctaaattcg tatcttctgc
    17581 tctaatagca aacccatcat acggtgaacg attgaatgaa ggtacgtcat gatcagctac
    17641 taaatcctcc gctaacatac gtccgtaagc taattcaata ggtagtagct cttttaagcc
    17701 attgttagca aatcccatca cttttcgaat agcttctgca accgtaattg gcactcttct
    17761 tcccattatt gacaatcctt tctattaacc gaataagcga taatatagtt gtttcgcttt
    17821 tggaatttcg tttgtaccat gaatgaacac acgaccatct tgaaaaataa cgacgcgata
    17881 atcctctaat tgacaagata gtaaatatgg attccgctct acttccccaa gtttttttaa
    17941 tactttttct acgtcatcaa aattgtattg cctattttct attgatctta tttgaactgt
    18001 atttcttccg cataaaacag ctaccttcgt ttggttttcg tatgataaat aaggataagc
    18061 tcgatttaaa ccgcacgatg gacaatcgtc cgtttttatt tttcctagtt ttataaaatg
    18121 attttgatta ctccatatat caaacatgaa aaacgtcttt ctaattactg agtaatcttc
    18181 cactaaaatt ttgagtgctt ctgccacttg atatgccgca acgatttgaa cagctggact
    18241 aataatccca gccgtgtcgc acgtcacacc tataacggga acattcttca gtacacaatg
    18301 taaacacggc attttttgcg gaataatcgt ataactcata ccgtacgatc caacacaaga
    18361 tccatatacc cacggaatat tatgtttttg tgataaatca tttatgataa atcgaatatc
    18421 aaaattatct gtagcatcaa tgattacatc gacattttct aatggccctt ccatgttttc
    18481 tacacttgca tccattatga aagcatgtat ttgtacttct gaattaattt gttccaaccg
    18541 ttttttagca gcaattgctt tcgggatttt ccctcttgca tcttcttcag agtaaagttg
    18601 ttgtctttgt aaattactcc actctacgta atcacgatca ataattgtca acttaccaat
    18661 acctgcacgc acgagacttt ctgcacttgt acttcctaat gcacctgctc ctacaattaa
    18721 cacatgctta ttccgaattt tttcttgccc tttactcccg attggtttga acaactgttg
    18781 ccgagaatac cgctcctcca ttgcataccc ttcctttcaa gaaatctatt tcacattaga
    18841 gtcttgtttt tgataacaag caaagtaagc aaaccctaca aatccagctc ctccaatgac
    18901 atttccgata aaaacaggaa caaagttttt agcgaggtcc agccacgtca gatgacctgc
    18961 aaaaataacc gctgatatga caaacatatt tgctactact tgttgaaatc caatcactac
    19021 aaatgccata attggaatcc aaatcccaat tatctttccg acaaaatcac tcgtcccgta
    19081 agcgagccaa agcgcaagac aaacgagcca attacaacca atcgccaaaa ttaaagttct
    19141 cccaaacgat tcgtgtaact ttccttccgc tatcgctaac gttttattta aataatctcc
    19201 ctctgttaat ccgccaagat gtccaaagca atacgcaacg aaaattgcac caacaaagtt
    19261 cattacagta atccaagccc aattattcag tacacttatc aatgtaattt tctttgcata
    19321 aagcgccata gacagtgaca tcatatttcc tgtaatcaat tctcctcctg ctaacactac
    19381 gagcataagc ccaataggaa acactgctcc tcctaaaaca ttcactaaac ttccccaatg
    19441 ctccggcaaa ttacctaata ctcgaatgtt aagtaaaaac cctaatgata taaatgctcc
    19501 tcctaaaaaa ccgagaataa gcattgctgg cagcgtctgg cttacttttt gaacaccggc
    19561 ctcgattacg agttcagcaa tttgttccgg tttatgaaat gccattacca attcctccat
    19621 tttctccaaa taaaaaagca gcttcaaaaa acctcctgaa aataaaggtt tttgaatgct
    19681 gcttaatgtc tctgcacatc ttttacagag agatcaatca tcacttttac tatgaaatag
    19741 aaagtccaca tctcttgcac actttccatt ttccactatt atgtcagcct tatatattaa
    19801 ccaccgatat gtgacatttc aattttaggc attgttttct tattagtatg acttaagcgt
    19861 tcgtctgaat atcgatcttc tcgattattc caaatgtcgt gaattacagc tgtaatttcc
    19921 tcatccgtat cccccgatcg aagcaatgct ctcaaatcat ttcctttaga agcaaataaa
    19981 caagtataca attttccttc tgcagaaatg cgagctctcg tacatgatga gcagaaagaa
    20041 tcagttacag atgaaatgat acctatttcc tcatcactgc ctatataacg gtacctagta
    20101 gctacttcac ctggataatt tgcttctatc cgttctaacg gcataacttc acgaattgta
    20161 tttactattt cttgtttgga aataacttca cctaactccc aaccgttata atttccaacg
    20221 tccatatact caataaaacg aagaatatgc ttattttcct taaagtattg cgccatctgc
    20281 aagatgtcct gttcgttttt ccccttttga acgaccatgt ttattttaat tttcatacca
    20341 acttcagccg cagcctgtat accctcaaga accctttgca ctttgcttct attaccattt
    20401 aaatagaaaa agcgctcttc ttctaaggaa tccagactaa ctgtcacacg tgataacccc
    20461 gctttatata aatcaggtgc aaacttttta agtaacgatc catttgttgt taaaccgata
    20521 tcctccacac catctatttt attaagccgc tcaataagct ctggaagccc tcttcgaagt
    20581 aacggctctc cgcctgtaat ccgtaacttt ctcacaccta aagaaacgaa aatacgtgtt
    20641 atcctttcaa tctcatcaaa agataaaatt ttatcattag acaaaaacga ataatcagga
    20701 ccaaatattt cttctggcat acaatatcga cagcgaaaat tacagcgatc agtaactgaa
    20761 atacgtaaat cctttaacgg acgatgcaat ttgtctaatg taattgattt catcttcctt
    20821 gcctcacttt tacttatttt atatttaaaa cacgttctgg atgcgtatat atatttaaag
    20881 actgattacg aataaaccct atcgtagtaa tccctaactc ttccgctaac tgcaaagcta
    20941 attcagttgg cgctgatttt gacagtataa tttcacagcc gatttttgca actttcaata
    21001 atatttctga agaaatacga ccactaaaaa caatgatttt atcttttata gaaatattat
    21061 tttttaaaca ataaccgtaa attttatcta gcgcattatg cctaccaata tccattcggc
    21121 ctaaaataat accatttaca tcacataaag ctgcgttatg cactccgcca gtatgtcgaa
    21181 atgtatccgc agattgctgc atttcattca ttaaacgaaa acaatcttcg acagcaacct
    21241 ttacatggac accattcatt ttctttacgc ttagtgcatc atttgcaaaa acaaaccctt
    21301 gcctactcat accacagcac gaagtaatat aacgtttatt ttgcatttgt tcgtaatacg
    21361 ggtttatttt tgttgtcgtc acatgtacaa atccttcttt ctcctgtacc catatgtgat
    21421 caatatcttc atacttccga ataattcctt cagatgctaa gaagcctatt accatatctt
    21481 ctatatattc tggagtacta accattgtaa caaactcctg tccgttcatt ttaattgtga
    21541 ctggaaactc tgttacaatg ctgtcctcta tatgcttaaa caccccttgt tcataacgga
    21601 aaacttctct ttctacctgt atcggtttca cgatcagcat ccttctctca cgttatattt
    21661 ttatcaaaaa caaataccga aacagcaata tcttcttcta ctttcatatc tgaaaataag
    21721 ttcactaagt tcgctccaac aagttcctcc aaatgttcac gagaattcgc agcgtaaact
    21781 tcttgaatca ttttcgttct agccatatga accatttccg cgccatccat cgtacttgaa
    21841 atgaatttct cagt
//
