LOCUS       NZ_KB976671            23507 bp    DNA     linear   CON 01-APR-2024
DEFINITION  Bacillus toyonensis strain HuA2-3 acrHg-supercont1.9, whole genome
            shotgun sequence.
ACCESSION   NZ_KB976671
VERSION     NZ_KB976671.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus toyonensis
  ORGANISM  Bacillus toyonensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 4008403)
  AUTHORS   Feldgarden,M., Van der Auwera,G.A., Mahillon,J., Duprez,V.,
            Timmery,S., Mattelet,C., Dierick,K., Sun,M., Yu,Z., Zhu,L., Hu,X.,
            Shank,E.B., Swiecicka,I., Hansen,B.M., Andrup,L., Walker,B.,
            Young,S.K., Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B.,
            Abouelleil,A., Alvarado,L., Arachchi,H.M., Berlin,A.M.,
            Chapman,S.B., Dewar,J., Goldberg,J., Griggs,A., Gujja,S., Hansen,M.,
            Howarth,C., Imamovic,A., Larimer,J., McCowan,C., Murphy,C.,
            Neiman,D., Pearson,M., Priest,M., Roberts,A., Saif,S., Shea,T.,
            Sisk,P., Sykes,S., Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     The Genome Sequence of Bacillus cereus HuA2-3
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4008403)
  AUTHORS   Feldgarden,M., Van der Auwera,G.A., Mahillon,J., Duprez,V.,
            Timmery,S., Mattelet,C., Dierick,K., Sun,M., Yu,Z., Zhu,L., Hu,X.,
            Shank,E.B., Swiecicka,I., Hansen,B.M., Andrup,L., Walker,B.,
            Young,S.K., Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B.,
            Abouelleil,A., Alvarado,L., Arachchi,H.M., Berlin,A.M.,
            Chapman,S.B., Dewar,J., Goldberg,J., Griggs,A., Gujja,S., Hansen,M.,
            Howarth,C., Imamovic,A., Larimer,J., McCowan,C., Murphy,C.,
            Neiman,D., Pearson,M., Priest,M., Roberts,A., Saif,S., Shea,T.,
            Sisk,P., Sykes,S., Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     Direct Submission
  JOURNAL   Submitted (07-DEC-2012) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Taxonomic-Update-Statistics-START##
            This Genome (query)               :: GCA_000399405.1
            Current Name                      :: Bacillus toyonensis
            Previous Name                     :: Bacillus cereus HuA2-3
            Date Updated                      :: 2022-03-10
            Analysis Type :: Average Nucleotide Identity (ANI)
            Analysis 1 (A1) :: Query vs. TYPE genome for current name
            A1 Genome (subject)               :: GCA_000496285.1
            A1 Name                           :: Bacillus toyonensis
            A1 ANI                            :: 99.4201%
            A1 Query Coverage                 :: 83.75%
            A1 Subject Coverage               :: 94.68%
            Analysis 2 (A2) :: Query vs. TYPE genome for previous name
            A2 Genome (subject)               :: GCA_006094295.1
            A2 Name                           :: Bacillus cereus
            A2 ANI                            :: 91.7421%
            A2 Query Coverage                 :: 77.41%
            A2 Subject Coverage               :: 80.96%
            ##Taxonomic-Update-Statistics-END##
            ##Genome-Assembly-Data-START##
            Assembly Method                   :: allpaths v. R41865
            Assembly Name                     :: Baci_cere_HuA2-3_V1
            Genome Coverage                   :: 108.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000399405.1-RS_2024_04_01
            Annotation Date                   :: 04/01/2024 01:17:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,841
            CDSs (total)                      :: 5,738
            Genes (coding)                    :: 5,542
            CDSs (with protein)               :: 5,542
            Genes (RNA)                       :: 103
            rRNAs                             :: 6, 4, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 196
            CDSs (without protein)            :: 196
            Pseudo Genes (ambiguous residues) :: 0 of 196
            Pseudo Genes (frameshifted)       :: 81 of 196
            Pseudo Genes (incomplete)         :: 115 of 196
            Pseudo Genes (internal stop)      :: 62 of 196
            Pseudo Genes (multiple problems)  :: 52 of 196
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:43:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 444447
            Orig. end                         :: 467954
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB976671.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The organism was changed from 'Bacillus cereus HuA2-3' to 'Bacillus
            toyonensis' in March 2022.
            Please be aware that the annotation is done automatically with
            little or no manual curation.
FEATURES             Location/Qualifiers
     region          1..23507
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23507
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23507
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13507](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13507)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            665..841
                     /locus_tag="IG5_RS10510"
                     /old_locus_tag="IG5_00473"
     CDS             665..841
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509719.1"
                     /locus_tag="IG5_RS10510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00473"
                     /product="hypothetical protein"
                     /protein_id="WP_000509719.1"
                     /transl_table=11
                     /translation="MGHDLGEEDASVTQNGYTYGDNNPVMLTNPDGQAPWLIPVAISGY
                     SAYKGYKGKSRVN"
     gene            911..1330
                     /locus_tag="IG5_RS10515"
                     /old_locus_tag="IG5_00474"
     CDS             911..1330
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084723.1"
                     /locus_tag="IG5_RS10515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00474"
                     /product="hypothetical protein"
                     /protein_id="WP_001084723.1"
                     /transl_table=11
                     /translation="MNSINIQSILDDLWGATILETHIDLLNDNIKFTLQVIDNGVIKDY
                     KLVLIEVSSFYYVKDDEKRRFAFYDREKVDYLELTTIYYEDPNLSEVKLSLQNEKEWSS
                     KYSTGVNIIIEIWDSILLVEAKQFSLNGKVINLKM"
     gene            1822..3459
                     /locus_tag="IG5_RS10520"
                     /old_locus_tag="IG5_00475"
     CDS             1822..3459
                     /GO_function="GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472903.1"
                     /locus_tag="IG5_RS10520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00475"
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="WP_000472905.1"
                     /transl_table=11
                     /translation="MFKKAAAIVLTSSIISIPITGLAETVTTSNTATVNVNAVKQSGWV
                     QQNGKWYYFNPDGTIKKGWLLDNNKWYYLNSSGIMQTGWLFDQGVWYYLNASGAMQTGW
                     LLDQGVWYYLNSNGSMKTGWLLDQGVWYYLNASGAMQTGWLLNQGVWYYLNSNGSMKTG
                     WLLDNNKWYYLNSSGGMKIGWLQDGNNRYYLQNDGSMKIGWLQVNNTWYYLNASGAMQT
                     SWSFIDGSWYYLQNNGAMKTDWLQDGDTWYYLQSNGMMQTGTASINGTTYHFDKSGAWT
                     PENNITATTYLDLDLTYASNVTGAEIDANIKKYHPDSPLIGHGNDFVEAQAKHGVNALY
                     LAAHAILESGYGKSEIAYRKHNLFGLRAYDADPFKYAKYLPTFGDSISYNANYVREKYL
                     EANGSYFNGPTLKGMNVMYSTDQEWSAKIVKIMERIKPFQKKDYVYAKKLPKNPNSLNV
                     DALSSDIPYKTYSQGTTKTVKLATSYYVVPYPFDGTIKSQSVTKNDQGTLATGTPVFIY
                     REDPNGWIEFSLTMNGNKYWVLKAGLNM"
     gene            complement(3663..4496)
                     /locus_tag="IG5_RS10525"
                     /old_locus_tag="IG5_00476"
     CDS             complement(3663..4496)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397498.1"
                     /locus_tag="IG5_RS10525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00476"
                     /product="hypothetical protein"
                     /protein_id="WP_000397501.1"
                     /transl_table=11
                     /translation="MEFVNSIFQILLTSVIQLFSLIGVIIVIGFLLGYLESLTRMYWSR
                     AFGRKGFLLTAWIGVPIHELGHAIMCVLFRHKIVATQFFPTDTSQGALGYVQHQYNQKS
                     VYQRIGNFFIGIGPIISGITALILFMRYFVPESYFLFNTTLEKTIASTSITLEMVQNML
                     LSTFVLLKSLFTINNLLNPSFWLFLFIAICISAHIALSKPDIKGSIDGVIVMFIVLFLF
                     NIIAELFQYDSNQLIGKVMKYNMYLIAFSSVALLFSCISTLVSFGFYKIRGGRSL"
     gene            4698..5483
                     /locus_tag="IG5_RS10530"
                     /old_locus_tag="IG5_00477"
     CDS             4698..5483
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000650096.1"
                     /locus_tag="IG5_RS10530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00477"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_000650065.1"
                     /transl_table=11
                     /translation="MKCPACHTENAVEAKFCGNCGHSLTEEVVASGVQEENQQSSHAEQ
                     AKETRPNETVEQAKRFTSGYFRFFKQAFQAPTAIMQSGNVEVRNGIVSLVLICFLGACI
                     FYRMMSAGAAVTRTLVPEVYTPTFFGESVTVFFFLLILTLFVGFIIFISGKMMKSSFSF
                     LEVFGIWGTIATPVIAILVLTFLFSFLLIFFLPILLSLATTYIGISIIVAILKLDNGGL
                     DLVYTLLIANVFIGIVTFIVLWSYISTVIQAFTQGLTGF"
     gene            5503..6738
                     /locus_tag="IG5_RS10535"
                     /old_locus_tag="IG5_00478"
     CDS             5503..6738
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016128956.1"
                     /locus_tag="IG5_RS10535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00478"
                     /product="YARHG domain-containing protein"
                     /protein_id="WP_001099924.1"
                     /transl_table=11
                     /translation="MNVCTKCGTQFVDGVQFCQNCGTKREIPVVKKKMGSGTKIGITFL
                     ALLVIAIVGLYLYGSSYYTQVAQVDRMITILQERDGEKLAEIITTDDPSVIVTRESFKP
                     LFSYIKENPSYVNELKQYLKQGEKQGDGIERADFSLTKDGKHYFIFDRYKLKARTYYTT
                     LLSNEKGASLKMNGKEIDKTEDKNFQKQYGPFLPGAQVFQVEYKNDYVKLSREEKVVLM
                     KQSQNNVTIDLTLQGQYITVQTNAPGATLYVNQKPVTALTGEEITWGPVATDGSATIYL
                     ERNGESGRETTKVETVTALSAYNLPFEKKSVEKTVVYNVTPPPTTGYVYNGFIFPDSDI
                     RKLTNADLTYVTKEQLKIARNEIYARHGNIFQTKDMQAYFSKQSWYRENPYFTGKLTDI
                     EAYNVELIKSRE"
     gene            complement(6785..7207)
                     /locus_tag="IG5_RS10540"
                     /old_locus_tag="IG5_00479"
     CDS             complement(6785..7207)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336278.1"
                     /locus_tag="IG5_RS10540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00479"
                     /product="hypothetical protein"
                     /protein_id="WP_000336278.1"
                     /transl_table=11
                     /translation="MCPGLLAQTPDEPQEPKAATPLDQEFSINATIYSARAWLSDNDTY
                     AQDIWKGTRFASASHAGKSIFPSGTIKVINLSADTITVTTSGDSDHNLKTVVAPYSEVA
                     LSPSSLSAVQASTSGKASKVTFLFHIFFSRDPGPAK"
     gene            7407..8741
                     /locus_tag="IG5_RS10545"
                     /old_locus_tag="IG5_00480"
     CDS             7407..8741
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110220.1"
                     /locus_tag="IG5_RS10545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00480"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_001110251.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3e-62, bitscore:
                     208.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYVIIGGDAAGMSAAMQIVRNDETANVVTLEKGEIYSYAQCGLP
                     YVISGAIASTEKLIARNVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAKHTETKDVFEFT
                     YDRLLIATGVRPVMPEWEGRELQGIHLLKTIPDTERILKTLETNKVEDVTIIGGGAIGL
                     EMAETFVELGKKVRMIERNNHIGTIYDADMAEYIHKEADKHHIEIVTNENVKAFRGKER
                     VEEIETDKGTYKADLVLVSVGVKPNTDFLEGTNIRTNYKGAIEVNAYMQTNVQDVYAAG
                     DCATHYHVIKEIHDHIPIGTTANKQGRLAGLNMVDKRRSFKGTLGTGIIKFMDLTLART
                     GLNEKEAKGLNIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVD
                     KRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE"
     gene            8818..9310
                     /locus_tag="IG5_RS10550"
                     /old_locus_tag="IG5_00481"
                     /pseudo=""
     CDS             8818..9310
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002135035.1"
                     /locus_tag="IG5_RS10550"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00481"
                     /product="GNAT family N-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVVALQRVQESEKEILRNLYALYLHDLSKFTTNITIGVNGFFGI"
     misc_feature    9419..9433
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.17"
                     /tool="antismash"
     gene            9561..9971
                     /locus_tag="IG5_RS10555"
                     /old_locus_tag="IG5_00482"
     CDS             9561..9971
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996799.1"
                     /locus_tag="IG5_RS10555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00482"
                     /product="DUF3908 family protein"
                     /protein_id="WP_000996796.1"
                     /transl_table=11
                     /translation="MAINMKTIEEWIAESNARQEEDFGHVVEEMKEVCVGLDNATLIYT
                     KNVFCFGKKVEVLFFFQDHVVIGQEKDEYVEIEKLKYDAITNSNLKTNDKNTTLELKFA
                     NGQTINLDSLNDNYGTKNWLFARQIKSIFKVI"
     gene            complement(10001..11542)
                     /locus_tag="IG5_RS10560"
                     /old_locus_tag="IG5_00483"
     CDS             complement(10001..11542)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016108035.1"
                     /locus_tag="IG5_RS10560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00483"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_016090937.1"
                     /sec_met_domain="PF00881 (E-value: 5.9e-09, bitscore: 34.1,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLDTFLHHLHFTIDEIMPNHEVDWEDAPLPYKLYRNVPVIPLSS
                     EIPISLPNSSTTPTLDEIGPYLLYSFGITQLCQLNSERNLFRRSIPSGGALYPNELYIY
                     LKLDHYPDGIYHYDAAYHRLILLREGNFDSYLTDALGNRCNIHSCFGAAFVSTMFWKNF
                     FKYNNFSYRLQGLDSGVLIGQLLECAKQFGYTNGIYFQFLDRAINHLLGLTEGEESVYA
                     VIPLSTEPNIDWFHDDYRKNKTVTSHDLLQQIPPLAHEHFVRSKHVEGYPMITKINEAS
                     MIESTEHFQTLAHEEYYQHHAHTVQLPKVERLSYDFLQLCKERYSPNDDFTLTKWDAAE
                     LATLLQETSLSFPYYNDLDGKYINENARVSLYGCFYNVKTIENGAYAYNSKTHSIHPIR
                     YGDLRYPLQSSMTMDNVNLFQVPLCLHVVGKKDYYTRALGYRGYRIHQMEAGILVHKLV
                     FAATAMGMGGHPLLSFDTNSCDQLYGIDGGNETSLIQIPVGAYRVRNWLKGSLHN"
     gene            complement(11558..13507)
                     /locus_tag="IG5_RS10565"
                     /old_locus_tag="IG5_00484"
     CDS             complement(11558..13507)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191877.1"
                     /locus_tag="IG5_RS10565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00484"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_016090938.1"
                     /sec_met_domain="YcaO (E-value: 1.2e-84, bitscore: 282.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.5e-143, bitscore:
                     476.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQHILLIGDGLLADYVHDQLRKQYSIIRQHTITDELPENINLAL
                     VLHDGSPSTIHHDAELVFRSNHIPWLRAFTSFGEGVIGPYIHPLATGCTHCADGRRFIA
                     GFDQQEMWELQRKYALKSEHVTRRDVRATQNGILQMCQLIHAETEKILAHGHSSLENEL
                     ILLNLQTLQCTRHSFLPDPLCPICSNLPTDTADAAQISLQPSLKTSAETYRCRSIHELN
                     TFLTRDYLDYRIGMLNGKMQHSLLPFADVIINMPLMFGNEGVAGRTHSFALSEATAILE
                     GLERYCGMSPRGKKTNVHGSFHDLEDHALNPLTLGVHTNEHYNRDNFPFKPFDPDYEQN
                     WVWGYSLSQNKPLLVPESIAYYSLGHRDAFVYETSNGCAIGGSLEEAIFHGILEIVERD
                     AFLLTWYAELPLPRLDLSSANDTELQLMIQRLRTITGYELHVFNATMEHGIPSLWVIAK
                     NTRANGMNVVCAGGSHLDPIRAIKSAIHEIAGMLLIADDELEQKREYYEKCLQDPYLVN
                     KMEDHSMLYGLKETEERLHFLLREDAPVQSFQEMNALQSFDMDLTSDLHQLLNRLHQSG
                     LEVIVVDQTVPLIEQNGLHCVKVMIPGMLPMTFGHHLTRVTGLDRVYTVPMTLGYRAEP
                     LTNEQLNPHPHPFP"
     gene            complement(13504..15423)
                     /locus_tag="IG5_RS10570"
                     /old_locus_tag="IG5_00485"
     CDS             complement(13504..15423)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513905.1"
                     /locus_tag="IG5_RS10570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00485"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_001061533.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1231.8,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     6.2e-55, bitscore: 181.1, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 1e-10,
                     bitscore: 39.4, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLPAHAKLKANKDTFFLPDSNGGVYFRNNASSFRMDGDGIYNW
                     IEKLMPMFNGDHSLAEITDGLPLPYQHRVFEIGEILYENGFVRDVSQDAPHELNSALLD
                     RYASQIEFLEADSHSGALKFQTYRAANVLILGSGDMLTSLVSSLLESGLPTFHYLVTDY
                     METNYDRIHELVERAYEVDDNVLVQEIDTTIDRPLHEVFEPFDWILYVSQNGDIEGLRT
                     VHTICKEVGKNFIPAICLSTFGLAGPVVTADREECWESAWHRLHETTLQNENASAPFSP
                     ITGAMLANIIVFELFKHVADDSYREKEPQFFLLNCETLEGTWHPFIKHPLATDESFTID
                     TIENLTEKLAQRSNQHTSTELFRFFDSLTSKEAGIFHVWDEQNSYQLPLSQCNIQVATP
                     LSDGPASLLPLMTCAGLTHNEARREAGLTGIETYVAEIIHRLIPEHNDIGIGAGETMTE
                     GVYRALQQHLNNKLYERQSHMLEEITTIDLAEIHDTHCKFYYDALSTIHEAPKIAMSEE
                     ILSFPVVWVGVNDRWYGASSINMTLALRNALQLSLLHIQNEETPYRATVLPESSIILYD
                     TDSFRIEIQADEEIPDVQSLQLALQHLGEHNFYPFMFDLAIESFLKENLDGVYGVLIAK
                     EDGL"
     aSDomain        complement(15124..15423)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IG5_RS10570_Heterocycloanthracin_C_RR
                     E.1"
                     /evalue="4.20E-57"
                     /identifier="RREFam011.1"
                     /label="IG5_RS10570"
                     /locus_tag="IG5_RS10570"
                     /protein_end="100"
                     /protein_start="0"
                     /score="181.1"
                     /tool="antismash"
                     /translation="MNNLPAHAKLKANKDTFFLPDSNGGVYFRNNASSFRMDGDGIYNW
                     IEKLMPMFNGDHSLAEITDGLPLPYQHRVFEIGEILYENGFVRDVSQDAPHELNS"
     aSDomain        complement(15157..15393)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IG5_RS10570_Thiopeptide_F_RRE.1"
                     /evalue="6.80E-13"
                     /identifier="RREFam004.1"
                     /label="IG5_RS10570"
                     /locus_tag="IG5_RS10570"
                     /protein_end="89"
                     /protein_start="10"
                     /score="39.4"
                     /tool="antismash"
                     /translation="KANKDTFFLPDSNGGVYFRNNASSFRMDGDGIYNWIEKLMPMFNG
                     DHSLAEITDGLPLPYQHRVFEIGEILYENGFVRD"
     gene            complement(15549..16808)
                     /gene="odhB"
                     /locus_tag="IG5_RS10575"
                     /old_locus_tag="IG5_00486"
     CDS             complement(15549..16808)
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716916.1"
                     /locus_tag="IG5_RS10575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00486"
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_000569924.1"
                     /transl_table=11
                     /translation="MIEIKVPELAESITEGTISQWLINVGDKVEKGGSVVELETDKVNV
                     EIIAEDSGIVSKLLGEPGDTVEVGATIAILDANGAPVAVSTPAPVAEQPKQETAEAPKA
                     AAPTAEQATALQGLPNTNRPIASPAARKMARELGIDLNDVRSTDPLGRVRPHDVQAHAA
                     APKEAPAAPKSPAPAPVAKTEFEKPVERVKMSRRRQTIAKRLVEVQQTSAMLTTFNEVD
                     MSAIMELRKERKDAFEKKHDVRLGFMSFFTKAVVAALKQFPLLNAEIQGDELIIKKFYD
                     IGIAVAAPDGLVVPVVRDANQLNFAEIESEIRNLGMKARDNKLSLKELQGGTFTITNGG
                     VFGSLMSTPILNSPQVGILGMHKIQVRPVAIDAERMENRPMMYLALSYDHRIVDGKEAV
                     SFLVAVKDMLEDPKSLLLEG"
     gene            complement(16939..19806)
                     /gene="odhA"
                     /locus_tag="IG5_RS10580"
                     /old_locus_tag="IG5_00487"
     CDS             complement(16939..19806)
                     /EC_number="1.2.4.2"
                     /codon_start=1
                     /gene="odhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197121.1"
                     /locus_tag="IG5_RS10580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00487"
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_000197133.1"
                     /transl_table=11
                     /translation="MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFE
                     IFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAA
                     NGQSLLEKAMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHI
                     QDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGV
                     DMLVPVLDEIVLEGAKGGVEDVMIGMAHRGRLSVLAHVLEKPYTHMFAEFKHAKIEGAV
                     ANAGWTGDVKYHLGREQVVGNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSG
                     LPEQDTSKSFVVLVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSY
                     DSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRTLFKKDFLIDLIGYRRYG
                     HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEVETITQFIQEQLKSDYA
                     QVPPADTSDATIHVKVPDVVAKGIQPIDTGVELDSLRAMNEGLLSWPEGFNVYPKVKKI
                     LERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTN
                     ETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQA
                     LFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSA
                     AQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGM
                     KPNKVKRLVLSTGKMAIDLAAEIESGKHEYNLDEVHVVRIEQLYPFPAEKVQSIMKRFK
                     NLEEIIWVQEEPRNMGAWHYMAPILFELAGDTVKTGYIGRPDRSSPSGGDPFAHKAEQE
                     LIVAHALDVKYNFRQDKQEIEVYSN"
     gene            20774..20989
                     /locus_tag="IG5_RS10585"
                     /old_locus_tag="IG5_00488"
     CDS             20774..20989
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428504.1"
                     /locus_tag="IG5_RS10585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00488"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000428507.1"
                     /transl_table=11
                     /translation="MENKMVEYRKKFGLSQEKLAEKLGVSRQTIISIEKGKYDPSLPLA
                     FEIAKTFQTTIEHVFIYEGKEEGEKG"
     gene            20986..21363
                     /locus_tag="IG5_RS10590"
                     /pseudo=""
     CDS             20986..21363
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016101524.1"
                     /locus_tag="IG5_RS10590"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="permease"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNDSQKYFVIMGIIFLIMSGFMILAGIMTHSAPPSPTYTLLAMMI
                     M"
     gene            21392..21574
                     /locus_tag="IG5_RS10595"
                     /old_locus_tag="IG5_00490"
     CDS             21392..21574
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086895.1"
                     /locus_tag="IG5_RS10595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00490"
                     /product="DUF3976 domain-containing protein"
                     /protein_id="WP_001178305.1"
                     /transl_table=11
                     /translation="MQMMYAFGMGIVLFLAVFLFIRKDVQGGTLTKRGFYKMIGCLVVM
                     FIAIIVMIVLITQSL"
     gene            21710..22072
                     /locus_tag="IG5_RS10600"
                     /old_locus_tag="IG5_00491"
     CDS             21710..22072
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034134.1"
                     /locus_tag="IG5_RS10600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00491"
                     /product="hypothetical protein"
                     /protein_id="WP_001034135.1"
                     /transl_table=11
                     /translation="MNKKAIFFLLTSLLLVASITYIICNTREQVPPILVWEDQEYYVTD
                     EPAQAEEVGQRLGEVTKKIEASKAPTKNSESNTLQEKTEVFTMIEEKKDDQSPLIIKEP
                     YGDEYRIVRPMLKQVL"
     gene            22090..22359
                     /locus_tag="IG5_RS10605"
                     /old_locus_tag="IG5_00492"
     CDS             22090..22359
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001195087.1"
                     /locus_tag="IG5_RS10605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00492"
                     /product="hypothetical protein"
                     /protein_id="WP_001193096.1"
                     /transl_table=11
                     /translation="MQTIASYPWSLRKIFVFFLCFILPPIGFIYILMNREALQKRDFIL
                     YVLFAAINISLWLSLMIFDRSMWMVAGHDVLSVIVIIVSNMNKG"
     gene            22440..22985
                     /locus_tag="IG5_RS10610"
                     /old_locus_tag="IG5_00493"
     CDS             22440..22985
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002168863.1"
                     /locus_tag="IG5_RS10610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IG5_00493"
                     /product="hypothetical protein"
                     /protein_id="WP_001267648.1"
                     /transl_table=11
                     /translation="MRWRAGTFEKIETNHASIEQIINTYKKQNLNGGAVISCFKVHNEN
                     FFKEIPHGEDGHEHFFRRICNSLDIINNLEELKIHTSDKYKFRFKEHQAVMLDGSIAAQ
                     ILWGGAYEAFQERPVAAKQLAINVCQYMFQDRYEDIKVFESDHPWTDWFYDVVWDATWM
                     VLDSKEHKMWLICATDTD"
     misc_feature    complement(22999..23015)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.71"
                     /tool="antismash"
ORIGIN
        1 ttagtaaata atacatggta ctatctaaac gctagtggtt ctatggtgac cggttggtta
       61 caaaaagatc gaaattggta ttacttacac tctaatggtg caatggcagt aggaaaacat
      121 ttcattgatg gtaaatggta tggttttaaa gaaaacggtg aaatgatgtc tgactggaag
      181 aatggaaaaa caggatggag aatagaaaac ggtaaactgt attatttaaa ccagaaaggt
      241 gtaaaagtaa ctgggtggct acaagatagt ggaaaatggt actactttaa tacaaaaggt
      301 gaagcggtaa taggttcggt gttcaataat ggtaagggct attatttgca aaatgatgct
      361 tcgatggcaa tagggtggat ttctcttgag ggtgaaaagt attattttga tgaaaatgga
      421 gtaagggcag caggttggaa agagatagat ggtaagtggt attctttctt cccacctact
      481 ggaaaaatga gcaaaaatac gtgggttgat agcaaatact gggtagatgc aaacggtgta
      541 tggacaaaga caagataact gaatagtaga taaaaaatac aaacctcatt aaaaaggttt
      601 gtatttttta tgagaactaa caggaatggg aaaaatatat aataaagtaa agaagggatt
      661 ttgtatgggg catgatctgg gtgaagagga tgcctctgta acgcagaatg ggtatacgta
      721 tggtgataat aatccagtga tgctgacaaa tccagatgga caggcacctt ggcttattcc
      781 tgtagcgata agtggctata gtgcttataa aggatacaaa ggcaaatcac gtgttaattg
      841 attaagaaag tcttataagc aaatacgtca tacattaaat aaaaaacgtt agaaaaggat
      901 gaaaagctac atgaatagta ttaatataca gtctatatta gatgatttat ggggcgctac
      961 cattttagag acacatatag atttgttaaa tgataatatt aaatttacat tgcaggtaat
     1021 tgataacgga gtgataaaag attataaatt agtattgata gaagtgtcat cgttttatta
     1081 tgttaaagat gatgaaaagc gtagatttgc attttatgat agagaaaaag tagattattt
     1141 agaattaaca acgatttatt atgaagatcc aaatctgagt gaagttaaat tgagtttaca
     1201 aaatgagaaa gaatggagta gcaaatattc cacaggagta aatattataa tagagatttg
     1261 ggattctatt ttgttagttg aagcaaaaca attttctctt aatggtaaag tgattaatct
     1321 taaaatgtag ttgtttttta gtatagttat ttcgttcgga gctgggtatc gtttaggggc
     1381 aaaaaattac aagcttgcca acacacctcc gtccaataaa aagcacttaa aacagggaat
     1441 gcaaaaagct ggaacaaaac tagaattaaa aacaatgtga tttaacattt tctttgagta
     1501 attagagtgt agtatataaa tttataatgg agagtaagca tcaaatttat taataataag
     1561 agggttttgc agcaccctct tattaaaaaa gaagaagatg tacaataaaa actaacgagc
     1621 tgactttaca agtcaacttt ttccaatcct tctatgaaca tgttccttta taaattcccc
     1681 ctaaaaactc aatattaata attcgaatat tatactatta aatatctaca atgttatagt
     1741 tgtttttttc gtcttccttg ttacaatagt agttagataa ctattaaact aaaaaattaa
     1801 taaaaggagt actaggaaga aatgtttaaa aaagctgcag caattgtctt aacatctagt
     1861 ataatttcta ttcctataac aggtttagct gaaactgtaa caacttctaa tacagcaact
     1921 gtaaatgtaa atgctgtaaa acaatctgga tgggttcaac aaaatgggaa atggtattac
     1981 ttcaatccag atggcactat aaaaaaagga tggcttcttg ataataataa atggtattac
     2041 ttaaattcaa gcggcattat gcaaactggc tggctgtttg atcaaggggt ttggtattat
     2101 ttaaacgcta gtggagcaat gcaaactggc tggctattag atcaaggagt ttggtattat
     2161 ttaaattcta atggttctat gaaaacgggt tggttattag atcaaggagt ttggtattat
     2221 ttaaacgcta gcggagcaat gcaaacgggt tggctattaa atcaaggagt ttggtattat
     2281 ttaaattcta atggttctat gaaaactggc tggcttcttg ataataataa gtggtattac
     2341 ttaaattcaa gtggcggaat gaaaattggt tggctacaag atggaaacaa ccgttattac
     2401 ctccaaaatg atggatcaat gaaaatcgga tggctgcaag tgaataatac gtggtattat
     2461 ttaaacgcta gtggagcaat gcaaacgagt tggtcattta tagatggaag ttggtactat
     2521 ttacaaaata atggtgcaat gaagacggac tggctacaag atggcgatac atggtattat
     2581 ttgcaatcca acggtatgat gcaaactgga actgcttcaa tcaatggaac gacgtaccat
     2641 ttcgacaaga gcggtgcttg gactcctgaa aataacatca ctgctaccac atatttagat
     2701 cttgatttaa cgtacgcttc aaatgtgact ggtgcagaaa ttgatgctaa tattaaaaaa
     2761 tatcatccag acagcccatt aattggacat gggaatgact ttgttgaagc tcaagctaaa
     2821 catggtgtca atgctcttta tttagctgca cacgctattt tagaatcggg atatggtaaa
     2881 tctgaaattg catatcgtaa acataaccta tttgggttac gtgcttacga tgctgatcca
     2941 tttaagtatg cgaaatattt accaactttc ggtgatagta tttcttataa cgcaaactac
     3001 gtaagagaaa agtacttaga agcaaacgga tcatacttta acggaccaac attaaaaggc
     3061 atgaatgtca tgtattcaac agatcaagag tggtctgcta aaatcgtaaa aataatggaa
     3121 cgtattaaac ctttccagaa aaaagattat gtatatgcga aaaaattacc taaaaatcca
     3181 aactctttaa atgtcgacgc cctatcaagt gatattccat ataaaacata ctcacaagga
     3241 acgacaaaaa ctgttaaact agctacttcc tattacgttg taccatatcc atttgatggt
     3301 acaattaaaa gtcagtcagt tacgaaaaat gatcaaggta cattagcaac gggtacacct
     3361 gtatttattt atcgtgaaga tccaaacgga tggattgaat tctcactcac aatgaatgga
     3421 aataaatatt gggtattaaa agctggatta aatatgtaaa taaaataccc cttttagaaa
     3481 aagctaaaag gggtatttta tatgttttaa attattaata ggtttgatga ggttaaagtt
     3541 gctgtgcgca aatatatgca cctgtataac tatcaaagat ttcaaaagaa attaaataac
     3601 ctgagtccat ataaatatag aactcaggtt gcttagttgc gcttttttaa tacgggggca
     3661 tttcacaatg aacgccctcc tcttatttta taaaacccaa aactaacaag tgtagaaata
     3721 caagagaaca gcagtgccac actagaaaat gcaatgagat acatattata tttcattact
     3781 ttcccaatga gttggttact gtcgtactga aaaagttctg ctattatatt aaataaaaac
     3841 aatacgataa acatgacgat gacaccgtca atggatcctt taatgtctgg tttacttaaa
     3901 gcgatatgtg cagaaataca aatagcgata aataaaaata accaaaagga agggttcaat
     3961 aaattgttta ttgtaaataa gcttttcaat aatacgaacg tcgacaagag catgttttga
     4021 accatttcta aagtaataga agtagatgca atcgtctttt cgagagttgt attaaataaa
     4081 aaatatgact ctggtacgaa atagcgcatg aaaaggatta atgcagtaat accagaaata
     4141 atagggccaa ttccaatgaa gaaattccca attcgttgat atacactttt ttgattgtat
     4201 tgatgttgta cgtaacctaa cgcaccttgg ctcgtatctg ttgggaagaa ctgcgttgct
     4261 acaattttat gacgaaatag tacgcacata atggcatgtc caagttcatg aataggaaca
     4321 ccaatccacg cagtcaaaag aaatcctttt cttccgaaag ccctcgacca atacattcgt
     4381 gtgagagatt ctaaataacc taatagaaat ccgattacaa tgatgactcc aattaaagaa
     4441 aataactgga tcacgcttgt aaggagtatt tgaaaaattg agtttacaaa ttccattgcc
     4501 tttcatccaa tctgtttaaa gtttcacttt agttgctctg tttcataata gcattatttt
     4561 tctagattac tagtctatat attttctttc aaaagcagga tttcataatc tgtttcttgt
     4621 agtcatgttt tatgtccaaa gtcatatatt gaacttgtaa catcctataa gatatatgct
     4681 taaggaggga tgagagcgtg aaatgtccag catgtcatac agaaaatgca gtagaagcaa
     4741 agttttgcgg gaattgtgga cattcgttaa ccgaagaagt agtagcaagt ggtgtccaag
     4801 aagaaaatca gcaatcatcg catgcagagc aagcgaagga aactcgtcca aatgaaacgg
     4861 tagagcaagc aaagcggttt acgagtggct attttcggtt ttttaaacag gcatttcaag
     4921 caccgacagc gattatgcaa agtggcaatg tcgaagtgcg aaatggaatt gtcagtcttg
     4981 ttcttatttg ttttttagga gcatgtattt tttatagaat gatgagtgct ggtgcagctg
     5041 ttacgagaac gctagtgcca gaagtatata ctcctacatt ttttggagaa tctgtaacgg
     5101 tatttttctt tttattaatt ttaactttgt ttgttggatt cattattttt ataagtggta
     5161 agatgatgaa atcctctttt tcgtttcttg aagtattcgg catatgggga acgatagcaa
     5221 cgccggttat tgctatatta gttcttactt ttctttttag tttcttatta atctttttct
     5281 taccgatatt attatcgtta gctacaactt atatagggat tagtataatt gtagccatat
     5341 taaaattaga taatggcgga ttagatcttg tttacacact tcttatcgca aatgttttca
     5401 ttggaatcgt aacatttatt gtactttggt cttacattag cactgtaatt caagccttta
     5461 cacagggatt aactggcttc taatgcaaag gtggttgaat ggatgaatgt atgtacaaag
     5521 tgtggaacgc agtttgtaga tggtgtgcaa ttttgtcaaa actgcggtac caagagagaa
     5581 attccagtag tgaagaagaa aatggggagc ggtacaaaaa ttggcattac atttttagca
     5641 ctacttgtta tagcgattgt tggattgtat ttgtatggat catcgtatta tacgcaggtg
     5701 gcacaagtag accggatgat tacgatttta caagagagag atggagaaaa attagctgag
     5761 attattacaa cagatgaccc atcggttatt gtaacgagag agagtttcaa gcctctattt
     5821 tcatatataa aagaaaatcc gtcttacgtg aatgaattga aacaatattt aaagcaaggt
     5881 gaaaagcaag gggacggaat tgaaagagcg gatttttctt taacgaaaga cgggaaacat
     5941 tactttatat ttgatcgata taaattgaag gcaaggacgt attatacgac tttgctttca
     6001 aatgaaaaag gtgcatcttt aaaaatgaac ggaaaagaaa tcgataagac agaagacaaa
     6061 aattttcaga agcaatatgg accatttctt ccaggagctc aagtgtttca agtggaatat
     6121 aaaaatgact atgtaaaact atcacgcgag gaaaaagttg tacttatgaa acaaagtcaa
     6181 aataatgtaa cgatagattt aacgttgcaa gggcaatata ttacagttca aacgaacgcg
     6241 cctggtgcga cattatatgt gaatcaaaag ccagttaccg cattgaccgg agaagaaatt
     6301 acgtggggtc ccgtagcaac tgatggaagt gcgacgattt atttagaacg caatggagaa
     6361 agcggaaggg aaacaacaaa agtagaaacg gtaacagcac tttcggctta taaccttcca
     6421 ttcgaaaaga aaagcgtaga aaaaacagtc gtttacaatg ttactccgcc acctacgact
     6481 gggtatgtat acaatggttt tatcttccct gatagtgata ttcgaaaatt aacgaatgca
     6541 gatttaacgt atgtaacgaa agaacagttg aaaattgcta gaaacgaaat atacgcaaga
     6601 catggaaata tatttcaaac gaaagatatg caagcgtatt tttcaaaaca gtcttggtac
     6661 agagaaaatc cgtattttac aggaaagcta acggatattg aagcttataa tgttgaattg
     6721 attaaatcaa gagaatagcg ttcgtgaaaa aggtacagtg tgtattactg taccttttct
     6781 atgattattt agctggacca ggatctcttg agaaaaagat gtgaaagaga aatgtgactt
     6841 tacttgcttt tcctgatgta ctagcctgta cggcggataa agaactaggt gataaagcta
     6901 cttcagaata gggtgctacg actgttttga gattatgatc tgaatctcct gatgtagtaa
     6961 ccgttattgt atctgcagat aagttaataa ctttaatagt accacttgga aatatagatt
     7021 taccagcatg tgatgctgaa gcgaagcgag tgcctttcca aatatcttgt gcgtaggtat
     7081 cgttgtcaga taaccaagca cgagcgctgt atatggttgc gttaatggaa aattcttggt
     7141 caagtggcgt ggcggctttc ggttcttgcg gttcatctgg agtttgagcg agaaggccag
     7201 ggcacatgta tgtttcacct actttcaata gttactgtta tagcatatta accatgttgg
     7261 ttataagaca cgacagttac ctattcaggc ataggtttgt gcactaaatt tgtagatgaa
     7321 atattatttc tttacaatgg gaataggtgt tatttctgta aaatatggaa attgtaaaga
     7381 gtaggtaaaa aagaaggagt ggtaaagtga actatgtcat tattggcgga gatgctgctg
     7441 ggatgagtgc agctatgcaa attgtaagaa acgatgaaac tgcaaacgtt gtgacgttag
     7501 aaaaaggtga aatctattca tacgctcagt gcggattacc gtatgtcatt agtggtgcta
     7561 ttgcttcgac ggaaaaatta attgcgcgta acgtgaagac gtttcgtgat aagtacggaa
     7621 ttgatgcgaa agtgcgacat gaagtaacga aagtagatac ggaaaagaaa attgtgtacg
     7681 caaagcatac ggagacgaaa gatgtttttg aatttacgta tgaccgttta ttaattgcga
     7741 cgggagtgcg tcctgttatg ccagaatggg aaggacgaga gttacaaggc attcatcttt
     7801 taaaaacaat tccagatact gagcgtatat taaaaacgct agaaacgaac aaagttgaag
     7861 acgtaacaat tattggcggc ggtgcgattg gactggagat ggcagaaaca ttcgttgaac
     7921 tcggtaaaaa agtgaggatg attgagcgaa ataatcatat cggtacgatt tatgatgcag
     7981 atatggcgga atatatacat aaagaagcgg ataaacatca tattgaaatt gtaacgaatg
     8041 aaaatgtaaa agcgtttaga ggaaaagagc gagtagagga gattgaaacg gataaaggta
     8101 cgtataaagc agatcttgtt ttagtatctg tcggagtaaa gccaaatact gattttcttg
     8161 aaggaaccaa tatacgtaca aattataaag gggcaattga agtaaatgca tatatgcaaa
     8221 cgaatgtgca agacgtatat gctgctggtg attgcgcgac acattatcac gttataaaag
     8281 aaattcatga tcatattcca attggaacga ctgccaataa acaaggacga cttgctggac
     8341 tcaatatggt tgataaacga agatcattta aaggtacgtt aggtacaggc attattaaat
     8401 ttatggattt gacactcgcg agaacaggct taaatgaaaa agaagcgaaa gggctcaata
     8461 tcccgtataa aacagttaaa gtagattcaa caaatatggc gggctattat ccaaatgcga
     8521 aaccacttta cttaaaattg ctatatcgct ccgatacgaa gcaattgttg ggtggacaag
     8581 taattgggga agaaggtgta gataagcgta ttgatgtgat tgcaatggcg cttttcaata
     8641 aaatgagcat tcacgattta gaagacgtcg acttaagtta cgcaccacca tataacagcg
     8701 tttgggatcc aattcagcaa gcagcaagga gagcggagta gcacttttaa agtgctactt
     8761 tttttgtaaa gggaagtaat cttttttatt gaataataaa gagggcgatt tataaaaatg
     8821 gttgtagcac ttcaaagagt tcaagaatca gaaaaagaaa tattacgtaa tttgtacgca
     8881 ttatatcttc atgacctttc caaattcacc actaatataa cgattggagt aaatggtttt
     8941 tttggaatat aaagatttac acttgttttg gaaaaatgac ggaatcactc catattttat
     9001 aaaaattgat aatagtattg taggattttt attattatta ttagaacgtc catttttgaa
     9061 gaaagaaaac gatttttgta tgaatgacat tttcatattg aatcaatata ggggaaaagg
     9121 aatcggtaaa caagttattg aaaatttact agaagagaaa cgaggacagt atttcgttat
     9181 cgaacttcta aaaaatgtac cggcagtttc gttttggaag aaagtatata gagagttaaa
     9241 cattgaattt gatgaacgaa aacaaatgat tgatgatgaa gaatgcctcg ttcaaacgtt
     9301 taaaatataa tgaaataagt gttcctcgta tattactttg aaatttagct ttatcccgct
     9361 atttgtggga gtcgggttgc tcgtaaacgc ccgattggtg agggctgata atcagtgggg
     9421 gatgaacagc cctcctactg attaaagttt cactttattt tgaatataag gttcaccctt
     9481 gaaaacaaag tacgtatcgc ttatattgtc atatagtatt tgttttttaa caaagcaatg
     9541 aacgaaccag ggggcgcagt atggcaatta acatgaaaac aatcgaggaa tggattgcgg
     9601 aatcaaacgc aagacaggaa gaagattttg gacacgttgt tgaagagatg aaagaagtat
     9661 gtgtcggact tgataatgcg acattaattt atacgaaaaa tgtattttgc ttcggtaaga
     9721 aagtagaagt attgtttttc ttccaagacc atgtcgttat cggacaagaa aaagacgaat
     9781 atgttgagat tgaaaaatta aagtatgatg ccattacaaa tagtaattta aaaacaaatg
     9841 acaaaaatac aacgttagaa ttaaagtttg ctaacggaca aactatcaat ttagatagtt
     9901 taaatgataa ctatggtacg aaaaattggt tatttgcaag acaaattaag agtatcttta
     9961 aagtaatcta gtaaaaagca cgccggtgga cggcgtgctt ttaattatgc aaagaacctt
    10021 ttaaccaatt ccgcactcga tacgccccaa caggaatttg aataagtgat gtttcatttc
    10081 caccatcaat cccgtacaat tgatcacaag aatttgtatc aaaacttagt aacggatgac
    10141 cacccatccc catagcggtc gcagcgaaaa cgagtttatg aacgagtata ccagcttcca
    10201 tttggtgaat gcgatatcct ctatagccta atgcacgtgt gtagtaatcc ttctttccaa
    10261 ctacatgtaa gcaaagtggt acttgaaaaa ggtttacgtt atccatcgtc atactagact
    10321 gaagggggta acgaaggtct ccataccgaa ttgggtgtat ggaatgtgtt ttactgttat
    10381 aagcataagc cccgttttca atagttttta cgttataaaa acatccatac aaggagacgc
    10441 gtgcattttc atttatatac ttgccatcaa ggtcgttgta ataggggaag gagagactcg
    10501 tttcttgtag taaagtagcg agctcagctg catcccattt cgttaaagta aagtcatcgt
    10561 taggggagta ccgctcttta caaagctgta agaaatcata cgataaacgc tctactttcg
    10621 gtagctgtac agtgtgcgca tgatgttgat agtactcttc atgagctagt gtttggaagt
    10681 gttctgtcga ttcaatcata gatgcttcat ttatttttgt tatcatcgga tatccttcca
    10741 catgtttgga acgaacgaaa tgctcatgtg ctaaaggtgg aatttgctgc aataagtcat
    10801 gagaagtaac ggttttattt ttacgataat catcgtggaa ccaatctata ttcggttctg
    10861 tacttaaagg aataacagca tacacacttt cttctccttc ggtcagtccg agtaaatgat
    10921 tgattgcacg gtctagaaat tgaaagtata tgccatttgt gtaaccgaat tgtttcgcac
    10981 attcgagtaa ttgaccgatg agaacgccgc tatctaatcc ttgcagacga tacgaaaagt
    11041 tattgtattt aaaaaagttt ttccaaaaca tagtggatac aaatgcagca ccaaagcaag
    11101 aatgtatgtt acagcgattg ccgagtgcgt ctgtaagata agaatcgaaa tttccttcgc
    11161 gaagtaagat aagtcggtga tacgcagcgt catagtggta aatcccgtct ggataatgat
    11221 ccaattttaa atatatatac aattcattcg gatataaagc accacctgaa gggatagacc
    11281 tccggaataa atttctttcg ctattgagct gacataattg ggttatacca aatgaataca
    11341 aaaggtaagg accaatctca tccaaagtag gtgtagtaga agagttcggc aaagatattg
    11401 ggatttctga agagagaggg atgacaggta catttcgata taacttataa ggaagcggtg
    11461 cgtcttccca gtccacctca tgattcggca taatttcatc aatagtgaaa tggagatgat
    11521 gtaaaaaagt atctagctgc atgaaatccc ccctttacta tggaaatgga tgaggatgtg
    11581 gatttaattg ttcgtttgtt aaaggctcag ccctatatcc aagtgtcatc ggtacagtgt
    11641 acactctatc cagtccggta acacgagtga gatggtgacc gaacgtcatc ggtagcatgc
    11701 ctgggatcat gacttttaca caatgtaatc cgttctgctc tataaggggg acggtttgat
    11761 ctacaacgat tacttcgagc ccagattgat gcaaacgatt taaaagttga tgaagatcag
    11821 atgtcaaatc catatcaaac gattgtaatg cattcatttc ttggaacgat tgcaccggag
    11881 catcttcacg taaaaggaaa tgaagacgtt cttccgtttc ttttaatccg tacagcatac
    11941 tatggtcttc cattttatta acgagataag gatcttgtaa gcatttttcg tagtactctc
    12001 ttttttgctc gagctcatca tctgctatta gtaacatgcc tgctatttcg tgaattgcac
    12061 tttttatagc tcgaatagga tctaaatgag agccccctgc acaaacaacg ttcattccat
    12121 ttgcacgcgt atttttcgca attacccata aactcgggat gccatgttcc atcgtcgcgt
    12181 taaaaacgtg taattcatac ccggtaatcg tgcgtaaccg ctgaatcatt aattgtaatt
    12241 ccgtatcgtt tgctgagcta agatcaaggc ggggaagagg taattcagca taccaagtga
    12301 gcaagaaggc atcacgctct acaatttcta aaatgccgtg aaaaattgct tcttctaaac
    12361 taccaccaat tgcacaacca ttggatgttt catacacgaa agcatcccga tgaccgaggc
    12421 tataataagc gattgattct ggaactaaaa gtggcttgtt ttgtgataaa gaatagcccc
    12481 atacccagtt ttgttcatag tcaggatcaa acggcttaaa cggaaaatta tcacgattat
    12541 aatgttcatt tgtatgtaca ccgagtgtga gaggattcag tgcatgatcc tctaaatcat
    12601 gaaaactacc atgcacattt gtcttttttc ctcgaggtga cataccacaa tatcgttcta
    12661 aaccttctaa aatagcagtt gcttcactca gtgcaaatga atgggttcga cctgcaacac
    12721 cttcattccc aaacattaac ggcatgttta taatgacgtc agcgaatggt aataaagaat
    12781 gctgcatttt tccattcaac ataccaatcc ggtaatctaa atagtctctc gttaaaaatg
    12841 tatttagttc atgaatagaa cgacagcgat acgtttcagc acttgttttt aagctcggtt
    12901 gtaaagaaat ctgtgccgca tccgcagtat cagtaggtaa attactacat ataggacaga
    12961 gaggatctgg aagaaaagaa tgccgcgtac attgcagtgt ttgtaagttt agtaaaatga
    13021 gttcattttc taaagaagaa tgtccgtgag ctaatatttt ctccgtttca gcatgaatga
    13081 gctggcacat ttgcagaatg ccattttgag tggcgcgtac atcacgcctc gttacgtgct
    13141 ctgatttcaa tgcatatttc cgctgtaatt cccacatttc ttgttgatca aatccggcga
    13201 taaagcgtcg tccatcggca caatgggtgc atcccgttgc aagaggatga atataaggtc
    13261 cgataacacc ttcaccaaat gaagtaaacg cacgtagcca cggaatatga ttggaacgaa
    13321 aaacaagctc agcatcatga tgaatagtag aaggagagcc gtcatgtaat acgagagcga
    13381 ggttgatatt ttcagggagt tcgtctgtaa ttgtatgttg gcgaatgatg gaatattgtt
    13441 tgcgtaattg atcatgtaca tagtctgcaa gtaggccatc tcctataagc aatatatgtt
    13501 gagtcataga ccgtcctcct ttgcaattaa taccccgtac acaccatcta aattttcttt
    13561 caaaaatgat tcaatcgcta aatcaaacat gaatggataa aaattatgtt ctcctaaatg
    13621 ctgcaaggca agctgtaaag attgcacatc tggaatttct tcgtccgctt gtatttctat
    13681 tcgaaaagaa tcagtgtcat ataaaataat agatgattcg ggcaaaacag tagctctgta
    13741 tggagtttct tcattttgaa tgtgaagaag agatagttgt agtgcgttac gtaacgctaa
    13801 cgtcatatta atactggatg cgccatacca tctatcattt acaccgaccc aaacgactgg
    13861 aaaactaaga atctcttcac tcattgctat tttaggtgct tcatgaattg tagagagagc
    13921 atcgtaataa aacttacaat gtgtatcatg aatttcagct aggtcaatcg ttgtaatttc
    13981 ttctagcata tgtgattgcc gctcatatag tttattgttt aaatgttgtt gtagtgcccg
    14041 gtatacacct tctgtcatcg tttccccagc accaataccg atatcgttat gttcaggaat
    14101 aaggcgatga atgatttcag ctacatatgt ttcaattcct gttaaaccag cttcacggcg
    14161 agcttcatta tgagtcaaac cagcgcaagt cataagaggc aggagggaag cgggaccatc
    14221 ggatagtggt gtagctactt gaatattaca ttgtgataac ggtagttgat atgaattttg
    14281 ttcatcccac acatggaata taccagcttc tttagaagtt aatgagtcga aaaaacggaa
    14341 caattcagtt gaagtatgtt ggttggaccg ctgcgcaagt ttttcggtaa gattttctat
    14401 tgtatcaatt gtaaaacttt catcagttgc gagaggatgt tttataaaag gatgccatgt
    14461 cccttcgagt gtttcacagt ttaataaaaa gaattgtggc tctttttctc gatatgaatc
    14521 atcagcgacg tgtttaaata attcaaaaac aattatattt gctaacattg cgccagtaat
    14581 tggtgaaaaa ggagctgatg cattttcatt ttgcaaagta gtttcatgta gccgatgcca
    14641 agctgattcc cagcattctt cacgatcagc tgttacgaca ggaccagcca aaccgaatgt
    14701 tgataaacaa atggcgggta tgaagttctt tcctacttcc ttgcaaatcg tgtgaactgt
    14761 tcttaagcct tcaatgtctc cattttgaga aacgtataaa atccagtcaa agggttcgaa
    14821 cacttcatgc agggggcggt caattgtagt atctatttct tgaacaagta cattgtcatc
    14881 aacttcatat gcacgttcta ctagttcatg aattcggtcg taatttgttt ccatataatc
    14941 tgtgacaagg taatgaaatg taggtaatcc ggattctagt aaagaagaaa ctaaggaagt
    15001 aagcatatcc ccagaaccaa gtataaggac atttgctgcg cggtacgtct ggaattttaa
    15061 agcacctgaa tgagaatcag cttctagaaa ttcaatttgc gaagcatacc tatcgagtaa
    15121 tgcactgttt aattcatgag gtgcatcttg acttacatca cgaacaaaac cattttcata
    15181 taaaatctct ccaatttcaa atacacgatg ttgatagggg agaggaagac catcggttat
    15241 ttctgctaaa gaatgatcac cattaaacat aggcattaat ttttcaatcc agttataaat
    15301 tccatcaccg tccatgcgga atgaactggc gttatttcga aaatagacac ccccgtttga
    15361 gtcgggaagg aagaaagtat ccttatttgc tttaagcttt gcatgagctg gaaggttatt
    15421 cattttaatc ctccttacgt tttaagcata cattattagc ttatgtcatg aaatttgtcc
    15481 cgtatgaacg caataaaaaa aggctgtaga atgatttatt ctacagcctc taatagacta
    15541 ttagtctatc aaccttctaa taataatgat tttggatctt caagcatatc tttaacagca
    15601 acaaggaagc taactgcttc tttaccatca acaatacggt gatcgtaaga tagtgcaagg
    15661 tacatcatcg gacgattttc catacgttct gcatcaattg caacgggtct tacttggatt
    15721 ttgtgcattc ctaaaatacc tacttgtggg ctgtttagga ttggtgttga cattagagaa
    15781 ccgaatacac caccgtttgt aattgtaaat gtaccacctt gtagctcttt taatgaaagt
    15841 ttattatcac gtgctttcat acctaaatta cgaatttcgc tttcgatttc agcgaagttt
    15901 aattggttag catcgcgtac aactggaaca actaatccat ctggagctgc tactgcaata
    15961 ccgatatcat agaatttttt aatgataagc tcgtcgcctt gaatttcagc atttaataat
    16021 gggaattgtt ttaatgctgc aacaactgct tttgtgaaga atgacataaa gccaagacgt
    16081 acatcatgtt ttttctcgaa agcatcttta cgctctttac gtaattccat gattgcactc
    16141 atatcaactt cgttaaatgt tgttaacatt gcagatgttt gttgtacttc tacaagacgt
    16201 tttgcaattg tttgacggcg gcgggacatt tttacgcgct caactggttt ttcaaattcc
    16261 gtttttgcaa ctggagcagg agctggactt tttggagcag ctggtgcttc ttttggtgct
    16321 gcagcatgag cttgtacatc atgtggtctc acacgtccaa gtggatctgt gctacgtacg
    16381 tcgtttaagt cgattcctaa ttcacgagcc atttttctag cagctggtga tgcgatagga
    16441 cggttcgtat ttggtaaacc ttgtagagcc gtagcttgtt cagcagttgg agcagcagct
    16501 ttcggtgctt cagctgtttc ttgttttggt tgctcagcca ctggtgcagg tgtacttact
    16561 gccactggtg cgccatttgc atctaaaatt gcgatagttg cgccaacttc aactgtatcc
    16621 ccaggctcgc ctagtaactt tgatacaata cctgaatctt ctgcaatgat ttctacattg
    16681 actttatcag tttcaagctc aacaacgctg ccacctttct caactttgtc acctacgttg
    16741 ataagccatt gtgaaatagt tccttctgta atagattctg caagctcagg tactttaatt
    16801 tcgatcattt taaatgtcct ccccttattt gcctaacggt gtgttttgtc ttctttaatc
    16861 ttcggtaatc tccatttgtt agctcgactt gggcagaata tctgcccaag tcgagccggg
    16921 aaaaattcat tgttactttt agttgctata aacttcaatt tcttgtttat cttgacggaa
    16981 gttatacttc acatctaaag cgtgcgccac aattagttct tgctcagctt tgtgagcgaa
    17041 cggatcgcca ccagatgggc tagaacgatc tgggcgtcca atgtaacctg ttttcactgt
    17101 atctccagct agttcgaaca gaattggagc catgtaatgc catgcaccca tattacgagg
    17161 ttcttcttga acccaaataa tttcttctaa gtttttaaag cgtttcataa tagattgaac
    17221 tttttcagca gggaatggat acaactgttc aatgcgaacg acatgaactt catctaagtt
    17281 gtattcatgt ttaccagact cgatttccgc tgctaagtca atcgccattt tacctgtact
    17341 taaaacaaga cgtttaactt tatttggttt catgccaagg ttttcttgtt ctaaagcagg
    17401 ttggaaacgt ccttcgctta actgactagc agttgaaagc gtaagtgggt gacgtaataa
    17461 actcttcggc gtcataagta ctaaaggtcg aacagcttct gttcctaaaa tagatgcttg
    17521 acgacgcaag atatggaagt actgtgctgc gctcgttaag tttgcaactg tccagttgtt
    17581 ttcagcagct aactgtaaga aacgctctgg acgtgcacta gaatgctctg gtccttgacc
    17641 ttcataaccg tgtggtaata gaagaactaa accagatttt tgaccccatt ttgctcttcc
    17701 agctgaaacg tattgatcaa ataatgcttg cgcagtattt gagaagtcac catattgcgc
    17761 ttcccacata acaagagttt ctggagcaaa tacgttataa ccatactcgt aaccaacaac
    17821 agcagcttct gataacggac tgttatgaac agagaatgaa gcgttaatgt ttggtaagcg
    17881 atgtaatggt gaatatgttt catttgtatc agtatcgtgt aatacgatgt gacgatgcgc
    17941 gaatgtacca cgctgtgagt cttgaccagt taaacgaatt ggtgtacctt cttgtaaaat
    18001 agaagcgaat gctaatgact cagcaagtgc ccattcaatt ttaccgttct cttcaagagc
    18061 atctttacgg cgttcaagaa ttttcttcac cttcggatat acgttaaagc cttctggcca
    18121 agataataga ccttcattca ttgcacgaag tgagtcaagt tcaacaccag tatcaattgg
    18181 ctgaatgcct tttgcaacaa catctggtac tttaacgtga attgttgcat cgctcgtatc
    18241 agctggtggt acttgtgcat aatcagattt taattgttct tgtataaatt gagtaattgt
    18301 ttcaacctca tctgcattta gaacaccagc agcttgtaat tgatctgcat aaattgctct
    18361 tacagttggg tgatttttaa tttttttgta cacttgtggt tgcgtaactg ctgggtcatc
    18421 catttcgtta tgaccgtagc gacggtaacc aattaaatcg attaagaagt cttttttgaa
    18481 caacgtacga tattgaatag ccaggttagc agcagcaaga caagcttctg gatcatcagc
    18541 gttcacgtga acaatcggaa tatcaaaacc ttttgcaagg tcgcttgaat atttcgtaga
    18601 acgagaatca tagctatcag tcgtaaaacc aactgcattg tttgcgataa catgaattgt
    18661 tccgcccgtt tgatacgcgt tcaatctgct taagtttagt gtctcagata caataccttg
    18721 accagggaat gcagcgtcac catgaactaa aactacgaat gatttagaag tatcttgttc
    18781 tggaagacca gactttttac gattctcttg agctgcacgt gcgaaacctt ccacaacagg
    18841 gttaacgaac tcaaggtgac tcgggttatt cgctaatgta acgcgagtgc taacttcttc
    18901 attcccaacg acttgttctc tacctaaatg gtatttcacg tcgccagtcc atccagcatt
    18961 tgccactgcg ccttctattt ttgcatgttt gaattcagca aacatgtgag tatatggttt
    19021 ttctaatacg tgagcaagta cgcttagacg cccgcggtga gccataccaa tcatgacatc
    19081 ttcaacgccg cctttagcac cttcaaggac aatttcatct agaacaggta caagcatatc
    19141 aacgccctcg atagagaaac gcttttgccc aacgaatgtt ttatgcaaga attgctcgaa
    19201 accttcaaca gctgttaaac gttttaaaag agcagtacgt tttttatttg ataatggttg
    19261 acgcaatgaa tttgattcca ccatttgatg caaccacgcg cgttcttcac tatcttgtat
    19321 atgtgagaat tcataagcta aagattttgt ataaacgtct tttaatctat gaattacatc
    19381 aagtgcagtg tgaataccct ctggtgcatc ttgccatact gttttagctg gaatcgcttt
    19441 caagtcagca tcgctcaatt cgttcattgc tttctcaaga agagattgtc cgtttgcagc
    19501 atcttccatc gggttgatgt gagccaacgt atgcccgaaa gaacgaatct gttcaacaag
    19561 ttgaacgact ttaagaattt tttcaatgtt acctgtgttt tgaggagaaa aatgtgttgc
    19621 tgtgttgtcc cctgttacga catcatcttg aaacgaagga gctccaaaaa tttcaaaaag
    19681 ctcttgtaat tccggatcaa cagaacctgc tccagttacg taaagatcat actgttcaat
    19741 aacataacca aggttcggac catggaactt ggcccaaggg tttgtcgttg tattcttcct
    19801 cgtcatttgt ttaaacctcc caatgcatat aatccttttc ctatacaaaa ggtgcatttt
    19861 gctctttttc aataattgat gaactaataa ttaatgtaaa tgttgtcttt actcttatgt
    19921 tattacaata atttacataa taccaaacac tattacttat ctgttttgta aaaaaacatt
    19981 cacaataact tatcacccaa gttaatcttt catgttataa agtaatttta cagaaaaatg
    20041 gagtggatat atttggtata cctacactaa caactataat tgttgcattt acatataggt
    20101 ataatagtta gaatgtttcg ataaaataaa gttcgaatta tgtatattga aataataagc
    20161 gctttcattg atattataca acaatataac ggaatatagt ataaaaaata aaagattatg
    20221 aatttagagt aaactttatt tcggtagtgt taaatattga aaggaaaacg aaggatttct
    20281 acaaaaaaag tggctaaaca taaaaaatgc ttcataaacc gttagtttct attaatatgc
    20341 cgaaaaatac cgtaaaacaa ataacgcatt tcatctaata aagcggcaaa tgaaatattt
    20401 taaaaggata aaacaaatat ggagatatta aatttttata aaaatggaga agggatatag
    20461 taacggatat atacattgtt ccatgttgca ttacaaaata gacgtgctga aattgaaaaa
    20521 gtttcttcta taataaagtg aaactttaat cagtgtgggg tttgtccatc caccactgat
    20581 tattagcctt caccaatcgg gcagttattt cccacctaaa ttcctcgtat tcactgaatt
    20641 ttgaggtggg agtcttactg cctgttaatg cgggataaat agcgtgaaac aaactgaaat
    20701 atatgtaaag gaaacttgac gtaaagttta ctttacatat atactcgata taagggagga
    20761 gggagaaatt tccttggaaa ataaaatggt cgaatatcga aaaaaatttg gactatctca
    20821 agaaaaattg gctgagaaac ttggagtttc cagacaaacc atcatttcaa ttgaaaaagg
    20881 gaaatatgat ccatcacttc cattagcatt tgaaatagcg aaaacatttc aaacaacgat
    20941 agaacatgta tttatttatg aaggaaaaga agagggggag aaaggatgaa tgattcacaa
    21001 aagtattttg ttattatggg aattatcttt ttaattatga gtggatttat gatactagca
    21061 ggtataatga cacattcagc accaccaagt cctacttata cgttactagc aatgatgatt
    21121 atgtgattct gcttaagtta cttacacccg caatttaaag aaaaagatga gcgaatgaaa
    21181 ctcattcgtt ataaagggat gttcttcagt ttttttgcat taacagcgta ttatctcctt
    21241 ttctctatcg gcttaaattt aaaagtaatg acactatctg cggttgaact attacatata
    21301 cttatggcac ttacaatgag taccgtcttt atctcatttg ttgttttggc aaaaagatat
    21361 taagatggaa gagagaaagg aagattaaca tatgcaaatg atgtatgctt ttggtatggg
    21421 gatcgtttta tttttagcgg tgttcctatt cattcgtaaa gacgttcaag gcgggacgtt
    21481 aacgaaacga ggattttata aaatgattgg ctgtttagtt gttatgttta tagcgatcat
    21541 cgtaatgatt gtattaatta ctcaatcatt ataaatttta aaaatgaaac cttacttttt
    21601 gtaaggtttt tctttttgta taaaaaccta aaaattacca caaaaaccat ttactacatg
    21661 gaagctatat tgtataatcc aataaaataa tagaaaagga gaatagtata tgaataaaaa
    21721 agctatcttc tttttattaa caagtctact acttgtagct agtattactt atataatatg
    21781 taacacacga gaacaagtac cacctatatt agtatgggag gaccaagaat actacgttac
    21841 ggatgaacct gctcaagcag aagaagtcgg gcaaaggctc ggagaagtga caaagaaaat
    21901 tgaagcaagt aaagcaccta ctaaaaatag tgaatctaat acattacaag aaaaaacaga
    21961 agtattcaca atgattgaag aaaaaaaaga tgatcaatcg cctttaatca taaaggaacc
    22021 ttatggtgat gaatatagaa tagtaaggcc gatgttaaag caagtactat aatagaaaag
    22081 gagactcata tgcagacaat agcttcatat ccgtggtcgt taagaaaaat atttgtcttt
    22141 ttcctttgct ttattctgcc tcctatcggt ttcatttata ttttgatgaa tagagaagca
    22201 ctacaaaaga gagatttcat tttatatgta ttatttgctg ctattaatat atcgctttgg
    22261 ttatcattga tgatttttga taggagtatg tggatggtag cggggcatga tgtgcttagc
    22321 gtaattgtta ttattgtttc gaatatgaat aagggataac ccagcaattt taaagttgct
    22381 gggttttatt ttgatattta taatgaaata acaaatcttt aatagagagt agtggcatta
    22441 tgagatggag agcaggaacg tttgaaaaaa tagaaacaaa ccatgcatct attgaacaaa
    22501 ttataaatac atataagaaa caaaacttaa atggtggagc ggttataagc tgttttaaag
    22561 tacataacga aaactttttc aaagaaatac cacatggaga agatggacac gagcactttt
    22621 tcagaagaat ctgcaactct ttagatataa tcaataactt agaagaatta aaaatacata
    22681 catcagataa atataagttt cgttttaaag agcatcaggc agtcatgctt gatggtagca
    22741 ttgccgctca aattttgtgg ggcggagcgt atgaagcatt tcaagaacgg ccggttgctg
    22801 cgaagcaatt agcgattaat gtatgccaat atatgttcca agatcgatac gaagatatta
    22861 aagtgtttga aagtgaccac ccttggacag attggtttta cgatgttgta tgggatgcta
    22921 cttggatggt attagatagt aaggagcata aaatgtggtt aatttgtgct acggatacgg
    22981 attaaaagat aaagagtctt gtagaaatgc tacaaggctc tttatctttt gggaaagaat
    23041 agaaaataaa tcgtataaat gttatactaa aaaatgtttg taatgtaagt tttatactgt
    23101 tgtatagtga tggcttacta gaaaagaaaa ggtaaggtaa gaggagaatg aacgtgaaaa
    23161 aggtaaagaa attattgcta ctaatgatgg taatagggtt aacagttggt gttctagcag
    23221 gatgtgcaaa cccgaaagat actgctgaag aatttttaac agcaatacaa aaaggggatg
    23281 tagagaaggc tcgtacattc gttgaaagtg acaaggaatt taataaacta aatgaaaaaa
    23341 cagatgatgc tgaagcaaaa gaaatgctaa gcgcaattac gaaaaacttt aaatttgaaa
    23401 aactagaaga agtatcaaaa acagatgata aagcagaagt gaaagtgaaa attacatctg
    23461 ctgatctatc tgttgccgta acgaaagcaa tgggagaagt tatgcca
//
