LOCUS       NZ_KB944819            20729 bp    DNA     linear   CON 12-JAN-2024
DEFINITION  Enterococcus faecalis EnGen0359 strain TR197 acAqV-supercont1.5,
            whole genome shotgun sequence.
ACCESSION   NZ_KB944819
VERSION     NZ_KB944819.1
KEYWORDS    WGS; RefSeq.
SOURCE      Enterococcus faecalis EnGen0359
  ORGANISM  Enterococcus faecalis EnGen0359
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1526810)
  AUTHORS   Earl,A.M., Gilmore,M.S., Lebreton,F., Walker,B., Young,S.K.,
            Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B., Abouelleil,A.,
            Alvarado,L., Arachchi,H.M., Berlin,A.M., Chapman,S.B., Dewar,J.,
            Goldberg,J., Griggs,A., Gujja,S., Hansen,M., Howarth,C.,
            Imamovic,A., Larimer,J., McCowan,C., Murphy,C., Neiman,D.,
            Pearson,M., Priest,M., Roberts,A., Saif,S., Shea,T., Sisk,P.,
            Sykes,S., Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     The Genome Sequence of Enterococcus faecalis TR197
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1526810)
  AUTHORS   Earl,A.M., Gilmore,M.S., Lebreton,F., Walker,B., Young,S.K.,
            Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B., Abouelleil,A.,
            Alvarado,L., Arachchi,H.M., Berlin,A.M., Chapman,S.B., Dewar,J.,
            Goldberg,J., Griggs,A., Gujja,S., Hansen,M., Howarth,C.,
            Imamovic,A., Larimer,J., McCowan,C., Murphy,C., Neiman,D.,
            Pearson,M., Priest,M., Roberts,A., Saif,S., Shea,T., Sisk,P.,
            Sykes,S., Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2013) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: allpaths v. R42411
            Assembly Name                     :: Ente_faec_TR197_V1
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/12/2024 01:36:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,334
            CDSs (total)                      :: 3,260
            Genes (coding)                    :: 3,176
            CDSs (with protein)               :: 3,176
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 6, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 3, 1 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 47 of 84
            Pseudo Genes (incomplete)         :: 36 of 84
            Pseudo Genes (internal stop)      :: 25 of 84
            Pseudo Genes (multiple problems)  :: 20 of 84
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:10:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 719987
            Orig. end                         :: 740716
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB944819.1.
            Please be aware that the annotation is done automatically with
            little or no manual curation.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20729
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="2"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..20729
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20729
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10729](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10729)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     misc_feature    107..122
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: strong, score: 28.99"
                     /tool="antismash"
     misc_feature    578..592
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.08"
                     /tool="antismash"
     gene            complement(1997..3385)
                     /locus_tag="WOK_RS13800"
                     /old_locus_tag="WOK_01912"
     CDS             complement(1997..3385)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010712556.1"
                     /locus_tag="WOK_RS13800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WOK_01912"
                     /product="MFS transporter"
                     /protein_id="WP_002382423.1"
                     /transl_table=11
                     /translation="MIDRKKVILYTCCMSLFVVTMDVTVVNVALPSIQSDFHTNLSTLQ
                     WVTDGYTLMVASLLLLSGSTADRIGRKRVLQLGLACFGLASFLCGISQTPGQLIAFRML
                     QGIGGSMLNPVAMSIITQVFTEKLERAKAIGLWGSVTGISLGMGPIIGGLIVSYFSWRY
                     VFFVNVPIIAAAIILTQKFVPESKVEKTVKNDFVGQALMILFLFSSIYSIIGLPRKGLF
                     APDILSTGIIGCLAIVIFFIYEYNIDNPLINPRFFLSIPFTSASFLAIFGFIIYNGYLF
                     LNTLYLQEMRGFSPLEAGLSTIPLAFVSFLVAPRAGEMVGRIGTKRPIMLCGISMLAVS
                     FLQLFVTKTTPMIILFIIYIFLGIGFGMLNSPITITAIEGMPLSQSGTAAAIAVTCKQI
                     GNSLGVALPSLLITKPITSSLTRTPFTNVWLLFGCCAIAIIFLSYLSNSPLAKKSLRRV
                     RFYF"
     misc_feature    complement(3647..3663)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            complement(3767..4621)
                     /locus_tag="WOK_RS13805"
                     /old_locus_tag="WOK_01913"
     CDS             complement(3767..4621)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010821679.1"
                     /locus_tag="WOK_RS13805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WOK_01913"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_002369254.1"
                     /transl_table=11
                     /translation="MTIEKLEYFYTIAKYNSISKAASELHVSKSTLSASLKDLESELGH
                     LLFNRNGNSLTLNSYGDKIVQSVYIILNEAKKMKLNLHEMIENPVMRLGFGNTSLMYKV
                     TENEDQLNRFWECYHGSSFELLNKLENHELDFVITSADVNSPVLKKEQLIELKMYLCVS
                     REIKQEIEEEGFSCLTNYPFLFLPHHLDHLEATKSVLEMLQLTSPLVCCYDTLMLTRLI
                     EKSKGVYAVISLRKEQLQEIDSKLFFLPIERKQKFYLYRNVSSSVFVQPGQIKATLQKL
                     LET"
     gene            5013..5843
                     /locus_tag="WOK_RS13810"
                     /old_locus_tag="WOK_01914"
     CDS             5013..5843
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397393.1"
                     /locus_tag="WOK_RS13810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WOK_01914"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_002369253.1"
                     /transl_table=11
                     /translation="MKINYLGTGAAERIPGIFCNCKLCKYAREKKGREIRTQTQLIIDD
                     VLLIDFPGDSYLHLLQYDLCFADFDSLLISHWHSDHFYGEDLAYRMSGYALDIPNRLTV
                     YGNEAVKTFYQRAFDLEGRQDDTRLHYQVIQPYKCFTIANYTIYPLPAQHGNFSEDCFI
                     FVIDDGKDAFLSTHDTGYFTSEMFEYLEKSHLLLSIVSLDCTSQTNETGNSHMNWEENL
                     KLIAELKERKLVTDKTIYVANHFSHNGGLSYAEMAALSQKHEIITSYDGLEILT"
     gene            complement(5991..6845)
                     /gene="sprE"
                     /locus_tag="WOK_RS13815"
                     /old_locus_tag="WOK_01915"
     CDS             complement(5991..6845)
                     /codon_start=1
                     /gene="sprE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364098.1"
                     /locus_tag="WOK_RS13815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WOK_01915"
                     /product="serine proteinase SprE"
                     /protein_id="WP_002369252.1"
                     /transl_table=11
                     /translation="MKKFSIRKISAGFLFLILVTLIAGFSLSANAEEYIVPAESHSRQK
                     RSLLDPEDRRQEVADTTEAPFASIGRIISPASKPGYISLGTGFVVGTNTIVTNNHVAES
                     FKNAKVLNPNAKDDAWFYPGRDGSATPFGKFKVIDVAFSPNADIAVVTVGKQNDRPDGP
                     ELGEILTPFVLKKFESSDTHVTISGYPGEKNHTQWSHENDLFTSNFTDLENPLLFYDID
                     TTGGQSGSPIYNDQVEVVGVHSNGGIKQTGNHGQRLNEVNYNFIVNRVNEEENKRLSAV
                     PAA"
     gene            complement(6894..8426)
                     /gene="gelE"
                     /locus_tag="WOK_RS13820"
                     /old_locus_tag="WOK_01916"
     CDS             complement(6894..8426)
                     /EC_number="3.4.24.30"
                     /codon_start=1
                     /gene="gelE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369251.1"
                     /locus_tag="WOK_RS13820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WOK_01916"
                     /product="M4 family metallopeptidase coccolysin"
                     /protein_id="WP_002369251.1"
                     /transl_table=11
                     /translation="MMKGNKILYILGTGIFVGSSCLFSSLFVAAEEQVYSESEVSTVLS
                     KLEKEAISEAAAEQYTVVDRKEDAWGMKHLKLEKQTEGVTVDSDNVIIHLDRNGAVTSV
                     TGNPVDQVVKIQSVDAIGEEGVKKIIASDNPETKDLVFLAIDKRVNNEGQLFYKVRVTS
                     SPTGDPVSLVYKVNATDGTIMEKQDLTEHVGSEVTLKNSFQVAFNVPVEKSNTGIALHG
                     TDNTGVYHAVVDGKNNYSIIQAPSLVALNQNAVDAYTHGKFVKTYYEDHFQRHSIDDRG
                     MPILSVVDEQHPDAYDNAFWDGKAMRYGETSTPTGKTYASSLDVVGHEMTHGVTEHTAG
                     LEYLGQSGALNESYSDLMGYIISGASNPEIGADTQSVDRKTGIRNLQTPSKHGQPETMA
                     QYDDRARYKGTPYYDQGGVHYNSGIINRIGYTIIQNLGIEKAQTIFYSSLVNYLTPKAQ
                     FSDARDAMLAAAKVQYGDEAASVVSAAFNSAGIGAKEDIQVNQPSESVLVNE"
     gene            complement(8661..10004)
                     /gene="fsrC"
                     /locus_tag="WOK_RS13825"
                     /old_locus_tag="WOK_01917"
     CDS             complement(8661..10004)
                     /codon_start=1
                     /gene="fsrC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402207.1"
                     /locus_tag="WOK_RS13825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WOK_01917"
                     /product="GHKL domain-containing protein"
                     /protein_id="WP_002386893.1"
                     /transl_table=11
                     /translation="MILSLLATNVLLVSSFIVFVFLRVTLIKIECKIPLLSLLIVINLC
                     SFAALMLGYSWLIYALTVVIFTGFLLIHKKRFSIFKAIFLSVFTLLMVSFINYTEQTIL
                     SVFFQQIYQNKLLWIASNVLLLLINIWIALKIPNSVFLRLNRVLENSRIFFGCLLLLLI
                     LLLLFVFLISPEISPDFMRGFVTVNSSKLELLISVGLFLILIGLVIEAYLEEQRINTQL
                     LNNLTIYTEKIESINEELAMFRHDYKNLLYSLQIAISYEDILEIKRIYEETIAPTKKII
                     DNEEFELMKLNRLKNMELKALISMKINTAKQAKLKVIVDVPEVFILDTSIDLVVVIRLL
                     AILLDNAIENSAKSELKMFAISIFNKNETQEFVITNSVQAEFDFKVMKKTKFSSKSNPE
                     EHGWGLLYVKEIVDFSDQFDLQTSFNEGAVTQHLIIEKNHNSKKVVNE"
     gene            complement(10001..10729)
                     /locus_tag="WOK_RS13830"
                     /old_locus_tag="WOK_01918"
     CDS             complement(10001..10729)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634271.1"
                     /locus_tag="WOK_RS13830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WOK_01918"
                     /product="accessory gene regulator AgrB"
                     /protein_id="WP_002369249.1"
                     /sec_met_domain="AgrB (E-value: 9.5e-32, bitscore: 106.3,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIDWILKNIMDMDQEDQSGKTQWTKYYLTVYFSGLFNLLMILIL
                     SVLFGTLSETFIVYVVLIFLRPVAGGWHAKTKWLCRLESIVIYVAIPFVLKNSSVSLPF
                     IYKILLMCLLVVLFYWYAPQGTAIEPVQPSDLNVLKKQSLIRVCLLILCSLFVKEKIAS
                     VILYGLVIQGLMILPVTKNLIEGSVFMKFGKKIIKNVIEKRVAKVSDGVGTKPRLNQNS
                     PNIFGQWMGQTEKPKKNIEK"
     gene            complement(10818..11549)
                     /gene="fsrA"
                     /locus_tag="WOK_RS13835"
                     /old_locus_tag="WOK_01919"
     CDS             complement(10818..11549)
                     /codon_start=1
                     /gene="fsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109506.1"
                     /locus_tag="WOK_RS13835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WOK_01919"
                     /product="response regulator FsrA"
                     /protein_id="WP_080114097.1"
                     /transl_table=11
                     /translation="MAIYILEDQIIQAKALEVLLTNILHSRNIYNETIHLFSRSDELLQ
                     VAHQDAQLNIFFLDIQMNNYIQAGFEVAKEIRKTDSESLIVFISTHTELVLTSYKYMVS
                     ALQFIQKNVDFLDFQKEVETCVDAYIQQKENIKTKSEYIIINLKASSIKMDINDIYFFQ
                     TEYDHRVSMVGKNFKREFYGTLSKIEQLHPDLIRVHQSIIINKKYASKLNYKTHLLTMR
                     DGTEVPVSRRYYTQVKALFLT"
     misc_feature    11661..11676
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.55"
                     /tool="antismash"
     gene            complement(11968..13926)
                     /locus_tag="WOK_RS13840"
                     /old_locus_tag="WOK_01920"
     CDS             complement(11968..13926)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401391.1"
                     /locus_tag="WOK_RS13840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WOK_01920"
                     /product="amidase domain-containing protein"
                     /protein_id="WP_002382428.1"
                     /transl_table=11
                     /translation="MKRKKIKNQLLVLTSILVLLSLEVAPVVTLAAELPSSSLQTALSS
                     ETTITSEEKVTETTETTVATSTTSTSSSSSESSSSTDTTTESTSQSTTETTTTNTSSET
                     KKEPTEPTVSSEITQPVEQSQPPQVPVTKQEPEEPIQVPEANNNFVEENQAVSLNPSLK
                     VDEIASSNLKGYELPLLSSFGEKKRAVVVAEALRHVGKTKKEFNLTEQALTSSFLAQKI
                     YQQLFKIDIGSTPQEQMTFGKVRSIEEAEPGDLIFWQTAEGKTLQNGVYLGQGKYLIAA
                     AESDSKEKPEVIAQLENIYTAKQQPDSKEEKRLVVTNPFKEFILTEYGKEVLATYGASF
                     EMQKSEQTTAFIKKIGETARELGEKYDVFASVMIAQAILESGSGESQLAKEPYYNLFGV
                     KGSFQGNSVSFSTKEADQRGQLYTISAGFRDYGGYNDSLQDYVQLLRQGIDGNQDFYKP
                     AWRSEAKNYLQATRFLTGKYATDKQYDNKLNSLIAVYNLTQFDLPKTVDGLIIQSKNKL
                     SEAEQQQMHFPVYDGINYNRSGSYPVGQCTWYVYNRFKQLGTSVDEFMGNGSDWGRKGR
                     ALGYQVSSLPKAGRAISFQPGVAGADNQYGHVAFVEAVTSDGIIISESNVINDQTISYR
                     VLPNVIAYSSGVTYIGA"
     gene            complement(14008..19635)
                     /locus_tag="WOK_RS13845"
                     /old_locus_tag="WOK_01921"
     CDS             complement(14008..19635)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633936.1"
                     /locus_tag="WOK_RS13845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WOK_01921"
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="WP_025190989.1"
                     /transl_table=11
                     /translation="MGSNFKEEKMNKEYQGKKIYGKKHWLTFLLVSSSVLAFHSFVTMD
                     SQVVDAQEQTAKEDVADSATSVGAIVSIEKAEKNFVITYASGKKAQISILNDHLFRYHL
                     DPTGKFEEYPTPNDPKHVAKITAKTMADYGTQAFEQTNVTDSGNQFILENNGLKIMFEK
                     ESALMKVLDKKKNQVILEETAPLSFKNDKATQTLKQSSQENYFGGGTQNGRFTHKGTAI
                     QIVNTNNWVDGGVASPNPFYWSTAGYGVVRNTWKPGNYDFGSHDPQTTTTTHEGTDFDA
                     FYFFNDSSAGILKDYYELTGKPALMPEYGFYEAHLNAYNRDYWVKVAEGTAGAVKFEDG
                     NFYKEYQPGDLGNLNGTLESLNGEKENYQFSARAVIDRYKKNDMPLGWFLPNDGYGAGY
                     GQTDSLDGDVQNLKEFTEYAQANGVEVGLWTQSNLHPADPKNPKKGERDIAKEVSVAGV
                     KALKTDVAWVGYGYSFGLNGVEDAANVFVKETDGAVRPMIVSLDGWAGTQRHAGIWTGD
                     QTGGQWEYIRFHIPTYIGTSLSGQPNVGSDMDGIFGGKNKEINIRDFQWKTFTPVQLNM
                     DGWGSNPKTPFAFDQEATDLNRAYLKLKSMMMPYNYSIAKESVDGLPMVRAMALEFPNE
                     GTAYTKDSQYQYMWGPNLLVAPIYNGNQDEAGNSIRDGIYLPDEKQVWVDLFTGEKYQG
                     GRVLNGVKTPLWKVPVFVKDGSIIPMTNPNNNPKEIQRDQRSFLIYPNGTTSFNMYEDD
                     GISTSYEAGQSATTKINSQGPKSNEKGDLTVTIEPTKGSYKDFVDERSTTLDLLASEAP
                     ESVTAMVGGTEVTLKQAANKEEFLAGTNLYYFDKEFQVNQYLSEASGEKLNQSALSVKL
                     AKQSVTAKDVQITVKGFINKGTVDGGNTTVDDQLTIPANVAINEEKTTPSSLTLQWDQV
                     TEATSYEVERDGTVFGNIQTNTATFDGFSFLSEHTFRVRAVGKNGVSEWSEPIKGKTQD
                     DPYKETINQVKATSNLPEQPGAELKKLTDKDLSTGWHTNWSTGIANPSDGNFLSLKFDL
                     GAEYQMDKIEYLPRDNAGNGNILQLQYRTSKDGANWTEFSEPINWKQDALTKTIETKDQ
                     AYRFVEMKVLKSVGNFGSGREMLFYKQPGTEGILHGDITNDGTIDENDAMSYRNYTGLE
                     SVDSDFNGYVEKGDLNKNGVIDAYDISYVLRQLDGGIEIPDVEEIAGGLSLAVVNENGK
                     DTYLPGDTLTFILKGQDLKNINALSTKMSFDSSKFELVGQPATTNNTQQMENYSKYRKH
                     SNDVENLYLVLSNQGNKQLLNGSMDLVTFKVKVKETTRVKRATTVEQPLQFDMSQGLLV
                     GQGFQQATLSDFSVTVKPTELVDKELLQALITLNQARVEKEYTPETWAIFKPILDEAVA
                     VLANEQATQTDVSAAAENLEKAASQLEKMPDVANKADLEKAIQEGLAKKPSDGQEFTEE
                     TKKVLEESLAAAQKVFAQEKVTQEEIDQATKTLREAIAQLKEQPVAVDKETLKEQIAQA
                     RGRKPEEGYQFTKETEKQLQEAIQAAEAIVAKETATKEEVSEALNALETAMAQLKEVPL
                     VNKDQLQEVVKRAQQVTPSEGHQFTASSLQELQKALLAAKNTLKNPAANQKMIDEAVAE
                     LTSAIDGLQEEVLVTDKKALEAMIAKAKAIKPSAGKEFTSESKARLTEAIDQAEGILAD
                     KNARQEQIDIAEKNVKTALDSLEEQVLQTDKTKLKELLQKAETLKPKAGKQFTKASQEA
                     LAEAIKQAKALVEDPNATQEAVDKCLSILSQAIEAMAEEPISSNSTGNNGNHSTVSGTG
                     GVTSQGKGTATGGTTTKTTTSGTLPKANEVVSPIWSISGFLLIVSIGLGKLFFKNKKEQ
                     N"
     gene            complement(20139..20534)
                     /locus_tag="WOK_RS13850"
                     /old_locus_tag="WOK_01922"
     CDS             complement(20139..20534)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407764.1"
                     /locus_tag="WOK_RS13850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WOK_01922"
                     /product="hypothetical protein"
                     /protein_id="WP_002369244.1"
                     /transl_table=11
                     /translation="MDGMFANLTLRERRLLKQAQVGATISFILLFVPILTIILLHTSDL
                     LAKWLGIVGVIMVLPLLYFAWQILKIAYKDQKDNPTPPLWVPKVYGIGLSINPYHRFGK
                     LIFILLAVLIVGIIISLLFTPASQINH"
     misc_feature    complement(20681..20695)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.5"
                     /tool="antismash"
ORIGIN
        1 ttttcaaaag ctacatcata gttgtagtcc tttggttgca cttcttggaa tccttgtggt
       61 ttataaaaac gtaaaaggtt ttcctgattt aatttgtcag ataaacttaa cgattttttc
      121 acccaatcgt tatctttcgt gacttctgct tttaaatctg ctggaacttg gtctaatttt
      181 ttcccttgat tattgtagat ttccccacct agatacgaaa attgaggcgt tacaaaatcg
      241 ccatttctaa aaggaaccac ttgtttatat tgaggagata aaaggtccgt gccaaaatgg
      301 atataatttt tatcatcgac acctaaaaga tggtacagtg tcggtaaaac gtcaatttcc
      361 ccaccatatt cgtgcatgat tttcccttgc gtatagcctg gcatgtaaaa catcaaaggt
      421 actctttgca attgcgcatt gtcatagttt gtccacgttt ttggatcgcg gttgaaagct
      481 ttacataagt ccttgttgtt cgcatctgaa ataccgaagt ggtcaccata aataacaaaa
      541 atagaatgat tgtataaact tgttgtttgc aagtaatgga aaaattgttc tagcgattga
      601 tccaaatagt gcgctgttcg aacataatca tccacaatcg aattgcctgt gttcaattta
      661 ggaaacggga agttttggtc atccgtataa taaggggtat gattggtcac agttaaaaac
      721 ttcgcataga atggctgctg taaatgttca agctcactag ctgattcacg caacaattgt
      781 ttatctaaaa taccgtaacc tagcattttg tcatcttttg aaaaatatga ccgatcaaaa
      841 aagtattgat atcctaagtt tttatacaca tggtctcgat tccaaaaact ccccacattt
      901 ccatggaaaa cagcggttgt atagcctttt tgtcctaaaa ctgcgggagc cgcttcgaaa
      961 gtattgtctg atcctaattg tgtaaaaaga gagccttgcg gtaacccgaa tgttcctgtt
     1021 tccaacatgt tctccgcatc actcgttttt ccttgcccta cttcatgaaa gaaattatca
     1081 aaactgattg tcgctttgtt ttgataaagc tgatttaaaa acggtgtaac ctcttggcct
     1141 tggactttca tattaatcaa aaattgttga aaactttcta aatgaatcac aaatacattt
     1201 tttcctttgg caatcccggc atactgtgga ttaagcggta aattgttttg cttggtaaat
     1261 ttcatgattt caggtaattc gtttgaacta gcttctgctc ttacctcatt tgacatggct
     1321 gttttgacac catcgatggc tgtgaatgca tccaagccaa gatattttac aatataatta
     1381 cggtcaaaaa ttctttgaag caattgagga cgatcggttt cgcttaaaaa taagttaacc
     1441 gaaaagagca agacacttaa acaactaatt gagatcgcca atcttctgtt gataggtttg
     1501 gtcacaaaga cttgatgatt ccgtcgctgt ttaaaagagt aaaataccaa aacgagcagc
     1561 actaaagtat ctagccaata aaagacatcg tggaccctca ttaaggcaag taaatcacca
     1621 gaaattcctt ctgaaacttt tgaaaagcca aaaacagatt ggatggtaat aaagtcagtg
     1681 aattcacgat aaaaaataat attcaaatat aaaattaatg tatttaaaac atttaaaaga
     1741 gttaagctaa gcataaatgt tttatgcttt ttaaaataca aactaaaacc aaataataac
     1801 agcgtagtag caactggatt gaaccataaa atttctcgct ggagactgcc cttaacaccc
     1861 aatgagaaat ctaggtaata cgccagaatc gtttttgccc aaaagagtaa aacaaaaaat
     1921 aaaaagagtc ctaatcggtt atttattttt ttcatctaag tttgtcttcc tttcccttca
     1981 aaaaaatctt gatttgttaa aaataaaacc taactctgcg caatgacttt ttcgctagcg
     2041 gagaattgga taaataactt aaaaagataa tcgcaatggc gcaacatcca aataaaagcc
     2101 atacgtttgt aaaaggtgtt cgagtaagcg aactagtaat aggctttgta attaaaagac
     2161 ttggtagcgc cacccctaaa gaattgccaa tttgcttaca tgtcaccgca atggctgctg
     2221 cagttcctga ctgagaaagt ggcattcctt caatcgctgt aatggtaatc ggtgaattta
     2281 acatcccaaa cccaatgcct aaaaagatat aaataataaa taaaataatc ataggcgttg
     2341 ttttagttac aaataattgt aaaaagctaa cagccaacat tgaaatacca caaagcataa
     2401 taggacgttt cgtccctatt ctccctacca tttcgccggc tctcggtgca acaagaaaac
     2461 taacaaaagc caaaggaatg gttgataagc cagcttccaa cgggctgaag cctctcatct
     2521 cttgcaaata tagcgtgttt aaaaataaat agccgttata tatgataaag ccaaaaatag
     2581 ctaaaaaaga agccgatgta aatggaatag ataaaaagaa acgcgggttg attaacggat
     2641 tgtcaatgtt atattcataa ataaagaaaa taacaatggc taagcagccg attatcccag
     2701 tacttaaaat atctggcgcg aaaagccctt ttctaggtag tccgataatg gaatagatag
     2761 aactaaatag aaaaagaatc atcaatgctt gaccaacaaa atcatttttc accgtcttct
     2821 ctacttttga ctcaggtaca aacttttgtg taaggatgat tgccgcagca atgatcggta
     2881 catttacaaa aaagacatac cgccagctaa aataagaaac aatcagtcca ccaataatcg
     2941 ggcccatgcc taaggaaatc cctgtaacag agccccacaa gccaattgct ttcgctcttt
     3001 ctaacttttc ggtaaatacc tgtgtaataa tagacattgc taccggattt aacatagaac
     3061 caccaatccc ttgcaacatg cgaaacgcga tcaattgccc tggggtttgc gaaatcccac
     3121 ataggaaaga cgctaaacca aaacaggcta agcccaattg aaggactcgt ttacggccaa
     3181 ttcgatctgc tgtagaccca gacaacaata ataaggatgc taccattaaa gtgtagccat
     3241 ctgttaccca ctgtaatgta gacagattcg tgtgaaaatc actttgaatg gatggtaacg
     3301 ccacattgac aaccgtaaca tccatggtca ctacaaacaa actcatgcaa caagtataca
     3361 aaataacttt ttttctatcg atcataaaaa cagtcctttc tagcaactac ataaaacagg
     3421 aaaagcaaca atgacactta aacttctaac gacacagtta tcgcaagtac tcacgtatca
     3481 acagttcttt atattccttg ccatttagtt attttatatt taaaaaagta aatctttaga
     3541 tagccaaact atacaccaga acccctttaa attgaaccgt aatagatacg atttatcgat
     3601 tcttaagtta ttaaataatt gaacattctg ttcagaaata tcgaacagcc ccataattga
     3661 gcatctcttt taaacaatga acaacaaaaa tagccttatc cgcagcagaa gtaaatctaa
     3721 gcgaataaag ctatttttgg taactattcc aaagtaattt taatggctaa gtctctagca
     3781 acttttgtaa agttgccttg atttgaccag gttggacaaa aaccgaactg gaaacatttc
     3841 ggtataaata aaatttttgt tttcgttcaa tcggtaaaaa gaagagttta gaatcaattt
     3901 cctgcagttg ttctttccga agagagatca ccgcataaac tcctttactt ttttcaatga
     3961 gacgagtaag catcaacgta tcgtagcaac aaacaagcgg acttgttaat tgcaacattt
     4021 ctagcacact cttggtagct tctaaatgat ctaagtgatg cggcaaaaat agaaatggat
     4081 agttggtcaa acagctgaag ccttcttcct caatttcttg tttaatttct cttgaaacac
     4141 aaagatacat ttttagttca attaattgtt ctttctttaa aactggacta ttcacatctg
     4201 cagaagtaat cacaaaatcc aactcatgat tctccaattt attcaataac tcaaacgatg
     4261 aaccatggta acattcccaa aaacgattca gttgatcctc attttctgtc actttataca
     4321 tcaaggacgt atttccaaaa cctaaacgca tcactggatt ctcaatcatt tcatgcaaat
     4381 taagtttcat tttcttagcc tcgtttaaaa tgatatatac agattggacg attttatcac
     4441 cataggaatt taacgtcaaa gaattaccgt tacggttaaa aagtaaatgg cccaattcac
     4501 tttccaaatc ttttaatgac gcacttaagg ttgatttact aacatggagt tcagaggctg
     4561 ctttggaaat actattatat tttgcaatgg tataaaaata ttctaatttt tcaatagtca
     4621 tcttttgtca tcccttttat tcaaattcat ttgcccacgc aacctgttca aaacacgcct
     4681 cactctttat caatagcgta gttatttttg ctctaataag ctatgtccat cttgttattt
     4741 ttctataact aatagcagat ggatatgaaa gtgcctttgg taaaactttt tttcggaaat
     4801 agtacgagca ttcgcagtaa attcagctta tcaaaaaagg cgtctagctt tttctatttt
     4861 acgcatattt acttaaaaaa ttccatttca attcttctct aaaaaaggta agatggacac
     4921 aacaaatgtt tcagtttcca tgcccattta ctttaaggtt cagcgttatc tactaagtat
     4981 gaagaatgtc aaagaaaggt taggtactcc caatgaaaat caactattta ggcacgggtg
     5041 cagcagaacg gattccagga attttttgta attgtaaatt atgtaagtac gctcgagaga
     5101 aaaaaggacg agaaattcgt acacaaactc aattaattat tgatgatgtc ctgctgattg
     5161 attttccagg ggattcttat ttacacctgt tgcagtacga cttgtgtttt gcagactttg
     5221 actctttact aatctctcat tggcattccg atcattttta cggcgaggat ttggcttatc
     5281 gaatgtctgg ttatgcatta gatattccca atcgtttaac tgtttatgga aatgaagcag
     5341 ttaagacgtt ttatcagcgc gcctttgatt tagaaggtcg tcaagacgat acccgattac
     5401 attatcaggt tattcagccc tacaaatgtt ttactattgc gaactatacg atttatcccc
     5461 ttcctgcaca acatggaaat ttcagtgaag attgttttat tttcgttata gacgatggta
     5521 aagatgcttt tttatccacc catgatacag gttactttac gtcagaaatg tttgaatatc
     5581 ttgaaaagag ccacttactt cttagtattg tttctttaga ttgtactagt caaacaaacg
     5641 aaactggcaa tagtcatatg aattgggaag aaaatttaaa attaattgca gaattaaaag
     5701 aaagaaaact cgtcacagat aaaacgattt acgttgccaa ccatttttct cacaatggcg
     5761 gcttgtctta tgcggagatg gcggctttat ctcaaaagca tgaaatcatt acgagttatg
     5821 atggtttaga aatactaact taatcggatt atttgccttc ttttcagcac tattatatgc
     5881 ttttaaccga taattacaag gtacttttat cgtaacttac actatcttaa aaaacaaaaa
     5941 tactcgagat ttcccgtgat tctggaaatt ccgagtattt ttatggttct ttacgctgct
     6001 ggcacagcgg ataaacgttt attttcttct tcattcactc gattaacaat aaagttataa
     6061 ttcacttcat ttagtctttg accatgattt cctgtttgct taatgccgcc attggaatga
     6121 acaccaacta cttcaacctg atcattatag attggtgaac cagattgacc gccggttgta
     6181 tcgatatcat aaaatagtaa tggattttct aagtctgtaa agttagatgt aaacaaatca
     6241 ttttcatgag accattgtgt gtggtttttc tcacctggat agcctgatat tgtgacatgg
     6301 gtatctgaag attcaaactt tttcaaaaca aatggcgtta aaatttctcc caactctggg
     6361 ccatctggac gatcgttttg tttgccgaca gtcactaccg caatatccgc attcggggaa
     6421 aaagctacat caatcacttt gaatttgcca aatggtgtcg cactgccatc tcgacctgga
     6481 taaaaccaag catcatcttt ggcattcgga tttaatactt tggcattctt aaaactttca
     6541 gccacatgat tattggtgac aattgtattg gttccaacaa caaagcctgt tcctaaagaa
     6601 atatagcctg gtttactggc aggggaaatg attcttccga ttgacgcaaa aggcgcttcg
     6661 gttgtatctg ccacttcttg tcttctgtcc tcagggtcca gtaacgatct tttttgtcgt
     6721 gaatgacttt cggcaggaac gatatactct tctgcatttg cagacaagct aaaaccggcg
     6781 atcaaagtta ctaaaatcag aaacaaaaaa ccagcactaa tttttcgtat ggagaacttt
     6841 ttcataagat tatgccactc cttatccatt tttatttaat tggggaattt ttttcattca
     6901 ttgaccagaa cagattcact tggttggttt acctgaatgt cctctttagc tccgattcca
     6961 gcagagttaa aggctgctga taccactgaa gctgcttcat cgccatattg aacttttgca
     7021 gcagcaagca tcgcatcacg agcatcactg aattgtgctt taggtgttaa gtaatttact
     7081 aacgagctgt agaaaatagt ctgtgctttt tcaatgccta agttctggat aatggtgtaa
     7141 ccaatccgat taataattcc actattataa tgaacaccgc cttgatcata ataaggcgtt
     7201 cctttatacc gtgctcgatc gtcgtattga gccatggttt ctggttgtcc gtgtttactt
     7261 ggcgtttgta aatttcgaat acctgttttt cggtcaacac tctgagtatc cgcaccaatt
     7321 tctggattag atgcacccga aataatataa cccatcaaat cagaataaga ttcattcaac
     7381 gcacctgatt gtcctaaata ttctaaaccg gcagtatgtt ccgttacacc atgtgtcatt
     7441 tcatgaccaa ctacatctaa agaggaagca tacgtttttc ctgttggtgt acttgtttca
     7501 ccataacgca ttgcttttcc atcccaaaaa gcattgtcat aagcatctgg atgttgttca
     7561 tcaacaactg acaagatggg catccctcga tcatcaatac tgtgtcgttg gaaatgatct
     7621 tcataatatg ttttcacaaa ttttccatgc gtataggcgt caacagcatt ctgatttaat
     7681 gctactagtg atggtgcttg aataatagaa taattatttt tgccatcaac tactgcatgg
     7741 taaacccctg tgttatccgt tccgtgtaaa gcaattcccg tattgctttt ttcaactggc
     7801 acattaaacg ctacttgaaa agagtttttt aacgttactt cactaccgac atgttccgtt
     7861 aaatcttgtt tttccataat tgttccatct gtagcgttca ctttataaac caatgatacg
     7921 gggtcaccag ttggcgaaga agttactctg actttataaa ataattgccc ctcattattt
     7981 acacgtttgt caatagctaa aaagacaaga tctttagttt ccggattatc agaagcaata
     8041 atttttttaa ctccttcttc accgattgca tcaaccgatt gaattttcac tacttgatca
     8101 actggatttc ctgtaacact tgttactgca ccatttctat ctaaatgaat aatcacatta
     8161 tctgaatcaa cagtaacgcc ttccgtttgc ttttctaact taagatgctt catcccccac
     8221 gcatcttctt ttcgatctac aaccgtatat tgttcagcag ctgcctcaga aattgcctcc
     8281 ttttccaact tcgataaaac tgttgaaact tcactttctg aataaacttg ttcttctgcg
     8341 gctacaaaaa gtgaagaaaa tagacatgaa cttccaacaa agatgcctgt acctaaaatg
     8401 tataaaattt tatttccctt catcaaacaa ttaactcctt ccccagtttc cttttatttc
     8461 ttttcccaac aaaagtattg ctttatcctc cctaattttt cccgttaaac gaccgcccct
     8521 ttccctgcgt aaatatttgt tgctattttc attatagaca actacctaac cggcactatc
     8581 taaattcctt aatcagccga catttttccc tgtattgccc ctcataactc aataccatag
     8641 caaaaaagtt gttaacaaat tcattcgtta acaacttttt tactgttatg atttttttca
     8701 ataattaaat gttgagtgac cgctccttca ttgaaggacg tttgcaaatc aaattgatct
     8761 gaaaaatcaa caatttcttt tacatataac aatccccaac cgtgctcttc tggattactt
     8821 ttagaactaa atttggtttt cttcataacc ttaaaatcaa attcggcttg gacactattt
     8881 gttatcacaa actcttgtgt ttcattttta ttgaaaattg agatagcgaa cattttcaat
     8941 tctgattttg cactgttttc aatcgcgtta tctaatagaa tagccaacaa acgaatcaca
     9001 accactaagt cgattgatgt atcaagaata aatacttctg gcacatcaac aatcactttt
     9061 agttttgctt gctttgcggt attaattttc atacttatga gtgccttaag ttccatattt
     9121 ttcaaacgat ttaacttcat aagttcaaat tcttcattat caataatttt tttggttggt
     9181 gcaatcgttt cttcataaat tcttttgatt tccagaatat cttcgtatga aatagcaatt
     9241 tgtaaactat acaataaatt tttataatca tgacgaaaca tcgctagctc ttcgttaatg
     9301 gattctattt tttcagtata aatcgttaaa ttattcaata attgagtgtt gatacgttgt
     9361 tcttccaaat aagcttcaat gactaagcca atcagaatta aaaataaacc tacacttatt
     9421 aataactcca atttagaact atttaccgtg acaaatcctc gcataaagtc aggtgaaatc
     9481 tctggcgaaa tcaaaaacac aaaaagtaac aacagaatca acaataaaag taaacaacca
     9541 aaaaaaattc ggctattttc taacacacga tttaatctta aaaaaacact attgggaatt
     9601 tttaaagcaa tccagatatt tataagcaac agaagaacat ttgaggcaat ccataataat
     9661 ttattttgat aaatctgttg aaaaaaaaca cttaaaatcg tttgctccgt gtaattgata
     9721 aacgaaacca taagcaatgt aaaaacagac aaaaatatcg ctttaaaaat tgagaacctc
     9781 tttttgtgaa tgagtaaaaa tcctgtaaaa ataacgactg tcagcgcata aatcaaccaa
     9841 gagtagccca acattaatgc cgcaaacgaa caaagattaa tgacaataag caatgaaagt
     9901 aacggtattt tacattcaat cttgatcaat gttactcgta aaaagacaaa aacgataaag
     9961 ctagatacaa gcaaaacgtt agtagctaat aacgacaaaa tcatttttca atattctttt
    10021 taggtttttc agtttgtccc atccattgtc caaatatatt gggcgaattt tgatttaatc
    10081 taggcttagt tcccacacca tcactaactt ttgcaactct tttttcaata acatttttaa
    10141 ttattttttt accaaatttc ataaaaacac ttccttcaat taaatttttt gttacaggga
    10201 gtatcatcag accttggatg acgagaccgt agagtattac tgaagcaatc ttttctttga
    10261 caaacagact acataaaata agtaaacaca cccttataag gctttgcttt ttgagcacgt
    10321 ttaaatcaga tggctgaaca ggttcaatcg ctgttccttg tggcgcatac caataaaata
    10381 atacgactaa gaggcacatc aatagaattt tataaataaa cggtaagctc acagaagaat
    10441 ttttcaatac aaatggtatg gcgacataga taacaatgct ttctagacga cagagccatt
    10501 tagtttttgc atgccagcca cctgcgacag gccgtaaaaa aatcagtacg acgtatacaa
    10561 taaaggtttc gcttaacgtc ccaaataaaa ctgataaaat cagaatcatc agaagattaa
    10621 ataagccaga aaaataaacg gttagataat actttgtcca ttgtgttttt cctgattgat
    10681 cttcctgatc catatccata atatttttta gaatccaatc gattagcata tcgccctcct
    10741 cttcaagtat tgcactaaat tataacgaat atagcgacta atagatagat aattccttaa
    10801 ttagtcatta tccctcccta agtaagaaat agtgccttga cctgagtata atatcttctt
    10861 gagactggta cttccgttcc gtctctcata gttaaaagat gcgttttata atttaatttt
    10921 gacgcatatt ttttattgat gatgattgat tgatggactc taatcaaatc tggatgcagt
    10981 tgttcaattt ttgataacgt tccataaaat tctcttttaa aatttttacc aaccattgac
    11041 acacgatgat cgtattccgt ttgaaagaaa taaatatcat taatatccat ttttatagaa
    11101 gacgctttta agttaatgat aatatattca ctttttgtct ttatattttc tttttgttga
    11161 atatatgcat cgacacatgt ttcgacctct ttttggaaat ctagaaaatc cacgttcttt
    11221 tgaataaatt gaagagctga aaccatatat ttgtaggaag ttaaaactaa ttctgtgtga
    11281 gtagaaataa atacaatcag actttcactg tctgtttttc tgatttcttt agcaacctca
    11341 aatcctgcct ggatataatt gttcatttga atatctagga aaaagatatt tagttgggcg
    11401 tcctggtgtg ccacttgtaa taattcatct gaacgtgaaa ataaatggat tgtttcatta
    11461 taaatatttc ttgaatgtag gatatttgtt aacaatactt ctaacgcttt tgcttgaata
    11521 atttggtctt ctaatatata aatagccatt tgttcactca tccctttctc aagaagatat
    11581 aaaattacac aacaaaagac aaatgattat aatgttcaat caatttatac accaataaaa
    11641 gagataaaaa attgattgtc tgttagtata ttcacataaa tttagtatag cgatttcagt
    11701 agtttcctgc aaacaaaaac ataaaataac aaaggatcaa gaaagagtac tttggactat
    11761 tcatcttttt ctaacgaatc atgaggacta ttgtctcttc gttgatgaaa aacaaagaat
    11821 caaccgccaa actgttcttg tcattttata catgacaaaa tcaattcatt ggtcgattct
    11881 ggttaattta atttgttagt tcacacatgg atcattgtac taatttttta cttaaacatc
    11941 cacacttctt cctgttgaat gagtcgctta agcgccaatg taggtcacgc cactactata
    12001 agcaattaca ttaggtaaga cacgatacga aatcgtttga tcattgatga cattgctttc
    12061 agaaataatg attccatcag aagtgaccgc ttcaacaaaa gcaacatgtc catattgatt
    12121 atctgcgcca gcaactcctg gttggaaact aatcgcacga ccagctttag gcaatgaact
    12181 aacttgatag cctaatgcac gtccttttct tccccagtca ctgccatttc ccataaattc
    12241 atccacagaa gtgcccaact gtttgaaacg attatagaca taccacgtac attggcccac
    12301 gggatagcta ccacttcgat tataattgat cccatcatag actggaaaat gcatttgttg
    12361 ctgttccgct tccgacagct tatttttaga ttggataatc aaaccgtcca ctgtttttgg
    12421 taaatcaaat tgggttaagt tataaaccgc aattaacgaa tttaatttat tatcgtattg
    12481 cttgtctgtt gcatatttac ctgttaaaaa acgcgttgct tgaaggtagt ttttggcttc
    12541 cgaacgccac gctggtttat aaaaatcttg atttccgtca atcccttgtc ggagtaattg
    12601 aacataatct tgcagtgagt cattatagcc accgtaatcg cgaaacccag cggaaattgt
    12661 ataaagttgg cccctctgat cagcctcttt tgttgaaaag ctaacactat ttccttggaa
    12721 cgaacctttc acgccaaaga gattataata aggttctttg gctagttgac tttcgccaga
    12781 gccactttct aaaatagcct gagctatcat tactgatgca aaaacatcgt atttttcgcc
    12841 aagttctctg gctgtctcac caattttttt aataaacgct gtggtttgtt ctgacttctg
    12901 catttcaaat gacgcaccat atgttgctaa aacttctttg ccatactccg ttaatatgaa
    12961 ctccttaaaa ggattagtca ctaccaagcg tttttcctct tttgagtctg gttgttgttt
    13021 ggcagtatag atattctcta actgagcgat tacttctggt ttctctttag aatccgattc
    13081 cgctgcggca attaaatatt ttccttggcc aagataaaca ccattttgaa gcgtttttcc
    13141 ttcagctgtt tgccaaaaaa tcagatcacc aggttctgcc tcctctatag aacgaacttt
    13201 accaaatgtc atttgttctt gcggcgtact gccaatgtct attttaaata attgttggta
    13261 aattttttgg gcaaggaaac tactggtcaa tgcttgctcc gtcaaattaa attctttttt
    13321 tgttttccca acgtgtctta atgcttcagc gaccacgact gcccgtttct tttcgccaaa
    13381 agacgacaac agtggaagtt cgtagccttt taaatttgaa gaagctattt catctacttt
    13441 gagggacgga tttaacgata cagcctgatt ttcttcaaca aagttattgt tggcttcagg
    13501 aacttgaata ggttcttcgg gttcttgctt ggtcacagga acttgtggtg gttgcgattg
    13561 ttcaacaggc tgcgtgattt ctgatgatac cgttggctct gtaggttctt tttttgtttc
    13621 agaactagta tttgtggttg tcgtttctgt cgttgactga ctcgttgatt cggtagtcgt
    13681 atcggtagaa ctacttgatt cagatgacga actactagtg gacgttgtcg atgtagcaac
    13741 agttgtttcg gttgtttcgg ttactttttc ttccgaagta attgtcgttt ccgaggacag
    13801 agctgtttgt agcgagctac ttggtaattc tgcagccaac gtaacaactg gagcgacttc
    13861 caaactcaga agaacgagaa tacttgttaa aacaagtagt tgattcttga ttttctttct
    13921 tttcattcgt aaaaatcctc tcctattact tacttgcgca tttgcacact gtttttgtac
    13981 aaatgcgcct tgtaagttaa tgatacgcta attttgctct tttttatttt tgaagaataa
    14041 ttttcctaaa ccaatactta ctatcaatag aaaaccactg attgaccaga ttggcgaaac
    14101 aacttcattt gcttttggca aagtaccaga agtggtggtt ttcgttgtcg ttccacctgt
    14161 tgctgtgccc tttccttggc tggttacacc accagtaccg ctaaccgtgc tatgatttcc
    14221 attgttgcct gtagagttgc tactgattgg ctcttctgcc attgcttcaa tggcttgtga
    14281 taaaatactt aaacatttgt ccacagcttc ttgcgtcgca tttgggtcct caacaagtgc
    14341 ttttgcttgt ttaattgctt cagctaaagc ttcttgcgat gcttttgtaa attgttttcc
    14401 tgctttaggt ttcaaggttt ctgctttttg aagcagttct ttcaactttg ttttatccgt
    14461 ttgaaggact tgttcctcta aactatccaa agcagttttt acattttttt cagcaatatc
    14521 aatttgttct tgccgagcat ttttatcagc taaaatccct tccgcttggt caattgcttc
    14581 agttaagcgc gctttagact cgctggtaaa ttcttttccg gcagatggtt tgattgcttt
    14641 tgctttggct atcattgcct ctaaggcttt tttatctgta actaacactt cttcttgtaa
    14701 cccatcgatg gcactagtta attcagcaac cgcttcatca atcatttttt gattagctgc
    14761 tgggtttttc aatgtgtttt tagctgctaa aagcgctttt tgtaactctt gtaacgagga
    14821 ggcagtaaat tggtgccctt cacttggagt gacttgctgc gctcgtttga ctacttcttg
    14881 taattggtct ttatttacaa ggggtacttc ttttaattga gccattgcag tttccaatgc
    14941 gtttagagcc tctgagactt cttcttttgt cgccgtttct ttcgctacga ttgcttcagc
    15001 cgcttgaatt gcttcttgca attgtttttc tgtttctttt gtaaattggt atccttcttc
    15061 cggctttctt cctcgggctt gagcgatttg ctcttttaag gtttccttat caacggcgac
    15121 gggttgttct tttaattgtg caattgcttc acgcaatgtt ttagtcgctt ggtctatttc
    15181 ttcttgagta actttttctt gagcaaatac tttttgagct gctgctaatg actcttcgag
    15241 aactttttta gtttcttcgg tgaattcttg cccatcactt ggtttcttcg ctagcccctc
    15301 ttgaattgct ttttctaaat cagctttatt cgctacatca ggcatttttt ccaactgact
    15361 tgcagccttt tctaggtttt ccgcggcagc agaaacgtct gtctgtgtgg cttgttcatt
    15421 ggctagaaca gctactgcct catctaagat tggtttaaag attgcccaag tttcaggcgt
    15481 atattctttt tcgacacgtg cttgatttag cgtaattagc gcttgtaata actctttatc
    15541 tactagctct gtgggcttca ctgttacaga aaaatctgaa agtgtggctt gttggaatcc
    15601 ttggcctact aataagcctt gactcatatc aaattgtaat ggctgctcaa cagttgtcgc
    15661 acgttttacg cgagttgttt cttttacttt aactttaaag gtaactaagt ccattgaacc
    15721 atttaacaat tgtttatttc cttgattact aagaactaaa tatagattct ccacatcatt
    15781 tgaatgtttc cgatatttag aataattttc catttgttgt gtattattcg tggttgcagg
    15841 ctgaccgaca agttcaaatt tgctagaatc aaaggacatt tttgtgctta acgcattaat
    15901 gttttttaag tcttgacctt taagtataaa ggttaatgta tcgccaggaa gataagtatc
    15961 cttgccattt tcattaacca cagcaaggga taaaccgccc gcaatttctt cgacatcagg
    16021 tatctcaatc ccaccatcta attgtcgtaa aacataactg atatcataag catcaattac
    16081 cccattttta tttaaatcac ctttttcaac atagccatta aagtcactgt ccacagattc
    16141 taagcctgta tagtttcgat aactcattgc atcattttca tcaatcgttc catcgttagt
    16201 aatgtctcca tgtaagattc cttctgttcc tggttgtttg taaaagagca tctcacgacc
    16261 agagccaaaa ttacccaccg attttaatac cttcatttca acaaaacgat acgcttggtc
    16321 cttcgtttca atggtttttg tcaaagcatc ttgcttccag ttaataggtt ctgaaaactc
    16381 tgtccaatta gctccatctt tcgacgtccg atactggagc tgcaaaatat ttccgttgcc
    16441 ggcattgtct cttggcaagt attcaatttt atccatttga tactccgcac caagatcaaa
    16501 ttttaaagac aagaaatttc catcacttgg attagcgatg cctgttgacc agttcgtatg
    16561 ccaacctgta ctcaaatctt tatctgttaa tttcttcaat tctgcgcctg gttgttctgg
    16621 taaattactt gttgctttga cttgattaat tgtttcttta tagggatcat cttgtgtttt
    16681 tcctttaatc ggttcactcc attcagagac cccgtttttt ccaacagctc gaactcgaaa
    16741 agtatgttcg cttaggaagg aaaatccatc aaatgttgct gtattcgttt gaatatttcc
    16801 gaaaacagtc ccgtcacgct ctacttcata gcttgttgcc tcagttactt gatcccattg
    16861 aagagtcaaa gaagatggcg ttgttttttc ttcattgatt gcgacatttg ccggaatagt
    16921 taactggtca tcgaccgttg tatttcctcc gtcaaccgtt cctttattaa tgaaaccttt
    16981 gacagttatt tgaacatctt tggcggtcac agattgtttc gctagtttta ctgataacgc
    17041 tgattggttc agtttttctc ctgaagcttc agaaagatac tgattcactt ggaattcttt
    17101 atcaaaataa tatagatttg tgccagctaa aaattcttct ttattagctg cttgtttcaa
    17161 ggttacttct gtccccccca ccattgctgt tacgctttcg ggcgcttctg aagctagcaa
    17221 atcaagcgtg gtgcttcgtt catcaacaaa gtctttataa cttccttttg tcggttcgat
    17281 agtaacggtc agatcccctt tttcgtttga tttagggcct tgactattta ttttagtcgt
    17341 agctgattgc ccagcttcat aactagttga aattccgtca tcttcataca tattaaaaga
    17401 agtggtgcca tttggataaa tcaagaaaga tcgttgatct cgttggattt cctttggatt
    17461 gttgtttgga ttcgtcattg ggataatact gccatctttg acgaaaacgg gcaccttcca
    17521 cagcggtgtt tttactccat ttaagacacg gccaccttga tatttttcgc ctgtaaataa
    17581 gtcaacccag acttgttttt catctggtaa gtagattcca tcacggattg aatttcctgc
    17641 ctcatcttga ttgccattat aaattggggc aacgagtaaa tttggtcccc acatatattg
    17701 gtattgagaa tcttttgtat atgctgttcc ttcattagga aattctaaag ccatggcccg
    17761 taccattggt agtccatcaa ctgattcctt ggcaatactg tagttataag gcatcatcat
    17821 tgattttaat tttagatacg ctcggttcaa atctgtggct tcttgatcaa aagcaaatgg
    17881 cgtttttgga ttggagcccc agccgtccat atttagctgc actggtgtaa aagttttcca
    17941 ttggaaatca cgtatgttga tctctttatt ttttccacca aaaattccat ccatatctga
    18001 accgacattt ggttgtccag acaacgaagt cccgatatat gttgggatat ggaagcgaat
    18061 atattcccat tgaccacccg tttgatcgcc tgtccaaata ccagcgtgcc gttgggttcc
    18121 ggcccaacca tctaatgaaa caatcatcgg acgaactgcg ccgtctgttt cttttacaaa
    18181 aacattcgcg gcatcttcta caccatttaa gccaaaggaa tacccatacc cgacccacgc
    18241 cacgtcagtt ttgagagctt taacaccagc gacactaact tctttcgcaa tatcccgttc
    18301 tcctttttta ggatttttag gatccgctgg atggagatta gattgagtcc acagccccac
    18361 ttcaacacca ttggcttgag catactctgt aaattctttt aagttttgta catcgccgtc
    18421 caatgaatct gtttggccat agccagcacc gtagccgtca tttggcaaga accaccctaa
    18481 cggcatatcg tttttcttat atcgatcaat aactgcgcgt gcagaaaatt gataattctc
    18541 tttttctcca tttaaagatt ctagcgtgcc atttaagttt cctagatcgc ctggttggta
    18601 ttctttgtaa aaattaccat cttcaaactt aactgctccc gcggttcctt ctgctacttt
    18661 cacccaatag tcccgattat acgcgtttaa atgcgcttca tagaacccgt attctggcat
    18721 caaagctggt ttcccagtta attcatagta atcttttaaa atacctgctg aggaatcatt
    18781 aaagaaataa aaagcatcaa aatctgttcc ttcgtgcgtt gttgtggttg tttgtggatc
    18841 atgacttcca aaatcatagt tgccaggttt ccatgtattt cgaacaacgc cataccctgc
    18901 agttgaccaa taaaatgggt taggcgatgc tactccgcca tctacccaat tgttcgtatt
    18961 gacaatctgg atagctgttc ctttatgcgt aaatcgacca ttttgagttc ctccgccaaa
    19021 ataattttct tgactacttt gttttaacgt ttgtgtagct ttatcatttt taaaggatag
    19081 cggagcggtt tcttctaaaa taacttgatt ctttttcttg tctagaacct tcattaaagc
    19141 gctttctttt tcgaacataa tttttaaacc attattttct agaataaatt ggtttcctga
    19201 atctgtgacg ttcgtttgct caaaggcttg tgtaccatag tcggccattg ttttagccgt
    19261 aattttcgca acatgctttg gatcatttgg cgttggatat tcttcaaatt taccagttgg
    19321 atctagatga tagcgaaaaa gatggtcgtt taaaatacta atttgtgctt tttttccaga
    19381 agcatacgta atgacaaagt ttttctccgc tttttcaatc gacacaattg ctccgactga
    19441 cgttgctgaa tcagctacgt cttcttttgc tgtttgctct tgcgcatcaa ccacttgaga
    19501 atccatcgta acaaacgaat ggaacgccaa tacagacgaa ctcactaata aaaatgtcaa
    19561 ccagtgcttt ttaccgtaaa tttttttacc ctgatactct ttgttcattt tttcctcctt
    19621 aaaattgctc cccatagaat agttccgaca aaattactca caaaatccaa aacccaacaa
    19681 agttttatcc agatgaaaag tcataacgat tttcttagtt tactgagact gttagaaagt
    19741 cagtttcagt aaccccttca taaacacatc ctttcaataa aatattaaat gaaaacaatc
    19801 tattttcatc ttatataaaa attttagtac agaatcataa tttcctaatg aatgcgtttt
    19861 catttgttga ctaccaattt ttcacttttt taataacata attatcgtat gatggttttt
    19921 ttgtgtttgt caacggttaa ttatagcagc caccattaac aagtattaac ccttgataaa
    19981 cctgttaatt cacttataat gatgatttta ttgcgaaaat atctacatca gaaaaagaaa
    20041 gactttttca aaaatctaat acctgttgct caaatctagt ctatttaaaa ataatcaaca
    20101 ccctcctgct cagcaagagg gtgttaatta ctcgtttttt agtgattgat ttgacttgct
    20161 ggtgtgaaaa gcaaactaat gatgatgcca actatcagta ccgctagcaa tataaaaatt
    20221 aactttccaa accggtgata gggattgatc gaaagcccaa tcccataaac tttcggaacc
    20281 cacaaaggag gcgttggatt atctttttga tctttatagg ctatctttaa aatctgccac
    20341 gcaaaataca acaatggtaa aaccataatt accccaacta tacctagcca ttttgctaat
    20401 aagtcactag tatgcaaaag aatgattgtc agaattggta caaacaaaag aataaagcta
    20461 attgtggctc ccacttgtgc ttgcttaagc agtcgtctct cacggagagt aagatttgca
    20521 aacattccat ccatcctttc atggttttca gattaaatca acgaatcact aaaaaactaa
    20581 attaactgcg aaaatcaatg accatgcgcc cgcgaatttt tccttgttcc atttcttcaa
    20641 aaatagcatt aatttcttct ggttgacgtg tttgacaaac aggaacaact tttccttctg
    20701 caccgaattg gaaagcttct cttaaatct
//
