LOCUS       NZ_KB944658            24328 bp    DNA     linear   CON 12-JAN-2024
DEFINITION  Enterococcus faecalis EnGen0364 strain T6 acAqR-supercont1.7, whole
            genome shotgun sequence.
ACCESSION   NZ_KB944658
VERSION     NZ_KB944658.1
KEYWORDS    WGS; RefSeq.
SOURCE      Enterococcus faecalis EnGen0364
  ORGANISM  Enterococcus faecalis EnGen0364
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1466244)
  AUTHORS   Earl,A.M., Gilmore,M.S., Lebreton,F., Walker,B., Young,S.K.,
            Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B., Abouelleil,A.,
            Alvarado,L., Arachchi,H.M., Berlin,A.M., Chapman,S.B., Dewar,J.,
            Goldberg,J., Griggs,A., Gujja,S., Hansen,M., Howarth,C.,
            Imamovic,A., Larimer,J., McCowan,C., Murphy,C., Neiman,D.,
            Pearson,M., Priest,M., Roberts,A., Saif,S., Shea,T., Sisk,P.,
            Sykes,S., Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     The Genome Sequence of Enterococcus faecalis T6
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1466244)
  AUTHORS   Earl,A.M., Gilmore,M.S., Lebreton,F., Walker,B., Young,S.K.,
            Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B., Abouelleil,A.,
            Alvarado,L., Arachchi,H.M., Berlin,A.M., Chapman,S.B., Dewar,J.,
            Goldberg,J., Griggs,A., Gujja,S., Hansen,M., Howarth,C.,
            Imamovic,A., Larimer,J., McCowan,C., Murphy,C., Neiman,D.,
            Pearson,M., Priest,M., Roberts,A., Saif,S., Shea,T., Sisk,P.,
            Sykes,S., Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2013) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: allpaths v. R42411
            Assembly Name                     :: Ente_faec_T6_V1
            Genome Coverage                   :: 145.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/12/2024 01:33:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,852
            CDSs (total)                      :: 2,769
            Genes (coding)                    :: 2,732
            CDSs (with protein)               :: 2,732
            Genes (RNA)                       :: 83
            rRNAs                             :: 7, 4, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 4, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 3 (23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 15 of 37
            Pseudo Genes (incomplete)         :: 18 of 37
            Pseudo Genes (internal stop)      :: 13 of 37
            Pseudo Genes (multiple problems)  :: 8 of 37
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:06:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1029468
            Orig. end                         :: 1053796
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB944658.1.
            Please be aware that the annotation is done automatically with
            little or no manual curation.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24328
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24328
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24328
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14328](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14328
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(80..93)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.16"
                     /tool="antismash"
     gene            complement(228..1946)
                     /locus_tag="WMM_RS13590"
                     /old_locus_tag="WMM_01985"
     CDS             complement(228..1946)
                     /EC_number="6.1.1.15"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /GO_function="GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /GO_process="GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359769.1"
                     /locus_tag="WMM_RS13590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01985"
                     /product="proline--tRNA ligase"
                     /protein_id="WP_002359769.1"
                     /transl_table=11
                     /translation="MKQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVAAGIYSYLPL
                     ANRVLEKLKTIMREEFEKIDAVEMLMPALLPAELWKESGRYETYGPNLYRLKDRNDRDY
                     ILGPTHEETFTELIRDEINSYKRLPLNLYQIQTKYRDEKRPRSGLLRGREFIMKDGYSF
                     HADEASLDQSYRDYEKAYSRIFERCGLEFRAIIGDGGAMGGKDSKEFMAISEIGEDTIC
                     YSTESDYAANLEMATSLYTPKKSHETQLDLEKIATPEVGTIAEVANFFEVEPQRIIKSV
                     LFIADEEPVMVLVRGDHDVNDVKLKNFLGADFLDEATEEDARRVLGAGFGSIGPVNVSE
                     DVKIYADLAVQDLANAIVGANEDGYHLTNVNPDRDFQPISYEDLRFVQEGDPSPDGNGV
                     LAFTKGIEIGHIFKLGTRYSDAMGATVLDENGREKSVIMGCYGIGVSRLLSAIVEQNAD
                     ERGINWPTGIAPFDLHVVQMNVKDEYQTKLSQEVEAMMTEAGYEVLVDDRNERAGVKFA
                     DADLIGCPIRITVGKKAVDGVVEVKIKRTGEMLEVRKEELESTLSILMNTTSEVE"
     gene            complement(2018..3286)
                     /gene="rseP"
                     /locus_tag="WMM_RS13595"
                     /old_locus_tag="WMM_01986"
     CDS             complement(2018..3286)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="rseP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359768.1"
                     /locus_tag="WMM_RS13595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01986"
                     /product="RIP metalloprotease RseP"
                     /protein_id="WP_002362168.1"
                     /sec_met_domain="Peptidase_M50 (E-value: 7.7e-84, bitscore:
                     277.2, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTIITFIIVFGILVLVHEFGHFYFAKRAGILVREFAIGMGPKIF
                     AHRGKDGTTYTIRLLPIGGYVRMAGMGEDMTEITPGMPLSVELNAVGNVVKINTSKKVQ
                     LPHSIPMEVVDFDLEKELFIKGYVNGNEEEETVYKVDHDATIIESDGTEVRIAPLDVQF
                     QSAKLSQRILTNFAGPMNNFILGFILFTLAVFLQGGVTDLNTNQIGQVIPNGPAAEAGL
                     KENDKVLSINNQKIKKYEDFTTIVQKNPEKPLTFVVERNGKEEQLTVTPEKQKVEKQTI
                     GKVGVYPYMKTDLPSKLMGGIQDTLNSTTQIFKALGSLFTGFSLNKLGGPVMMFKLSEE
                     ASNAGVSTVVFLMAMLSMNLGIINLLPIPALDGGKIVLNIIEGVRGKPISPEKEGIITL
                     IGFGFVMVLMVLVTWNDIQRFFF"
     misc_feature    3271..3285
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.91"
                     /tool="antismash"
     misc_feature    3481..3496
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.46"
                     /tool="antismash"
     gene            3702..4481
                     /locus_tag="WMM_RS13600"
                     /old_locus_tag="WMM_01987"
     CDS             3702..4481
                     /NRPS_PKS="Domain: PKS_KR (50-167). E-value: 3e-07. Score:
                     22.4. Matches aSDomain:
                     nrpspksdomains_WMM_RS13600_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376895.1"
                     /locus_tag="WMM_RS13600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01987"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_002359767.1"
                     /sec_met_domain="adh_short (E-value: 3.1e-30, bitscore:
                     101.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 3.5e-31, bitscore:
                     105.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYGELHGKVAVVTGAATGLGLFITLRYILEGMNVVADYVGELPKE
                     FEDVQAKHADRVKFVKADVSNEEDIKALAETALKEFGHVDIWVNNAGVEASFPTIDMPL
                     KEWQRVIDVNLNGVFLGSREALRIFRDQKIKGSIINMSSVHQRIPWPTFAHYAASKGAT
                     EMFTKTIALEYAEYGIRANCIAPGAINTPINAEKFSDPEQLKQTTSMVPMGIIGKPNQV
                     AAAAAWLASDESSYVTGTTLFVDGGMSLYPSFQHGAG"
     aSDomain        3852..4202
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_WMM_RS13600_PKS_KR.1"
                     /evalue="3.00E-07"
                     /label="WMM_RS13600_PKS_KR.1"
                     /locus_tag="WMM_RS13600"
                     /protein_end="167"
                     /protein_start="50"
                     /score="22.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="AKHADRVKFVKADVSNEEDIKALAETALKEFGHVDIWVNNAGVEA
                     SFPTIDMPLKEWQRVIDVNLNGVFLGSREALRIFRDQKIKGSIINMSSVHQRIPWPTFA
                     HYAASKGATEMFT"
     gene            4567..5169
                     /locus_tag="WMM_RS13605"
                     /old_locus_tag="WMM_01988"
     CDS             4567..5169
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002413059.1"
                     /locus_tag="WMM_RS13605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01988"
                     /product="membrane protein"
                     /protein_id="WP_002389010.1"
                     /transl_table=11
                     /translation="MKLVKNVLLILIGLVIIGIGASTLRVAGLGVDPFTAMNIGLSSMF
                     GMQLGIFQIIVNAFILFYVYLKNKKAIGLGTILNMLLVGILIQQISTWLQPYANSLGGS
                     TIGKLLSLFVGVLIFTFGCALYMATDQGESPYDAIAPTICQQINKPYASVRKAQDLLVL
                     LIGFIAGGPIGIGTIICAFGAGPLISFWNKLLQPLVK"
     misc_feature    complement(5615..5628)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.62"
                     /tool="antismash"
     gene            <5863..>6051
                     /locus_tag="WMM_RS18660"
                     /pseudo=""
     CDS             5863..>6051
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002392750.1"
                     /locus_tag="WMM_RS18660"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDITDKKANSPHIAITGPTVNGKSYLAKFIFFLSVLMNGKGLYVD
                     PKSEFFNRIMEVINHPLY"
     gene            <6056..6627
                     /locus_tag="WMM_RS13615"
                     /old_locus_tag="WMM_01989"
                     /pseudo=""
     CDS             <6056..6627
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002415745.1"
                     /locus_tag="WMM_RS13615"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="WMM_01989"
                     /product="CHAP domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="IQFSKTQADGKTVTYTNPIAINIGYDYRYAYGNMFYAQIVKQYIT
                     SISNNNSQGNSAIVKAALKELNEGIHKGGTKYWQWYGFNGRVEWCAIFVSYNAEKAGVK
                     MEHFAYCPTGIENFKANNQWFRKGSLPKNGNIIFFDWDGDSISYYVGIVEKVENEVVYT
                     IEENSGNKIAKLSYEKIALISWVMVFR"
     gene            complement(6678..7271)
                     /locus_tag="WMM_RS13620"
                     /old_locus_tag="WMM_01990"
     CDS             complement(6678..7271)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362865.1"
                     /locus_tag="WMM_RS13620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01990"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002362865.1"
                     /transl_table=11
                     /translation="MKVYLLDDHALFSKSLEIAFQPMDVSITSFTNPEFFLNKLKNEQP
                     DLALLDIHIGELSGFEISKEIIGKFPNQKIVFLSGFDLIEYKNEAIKSGAWGLLNKNVT
                     IEELYDDLQKIHHGTDLLPKCQSTLDVLSKREKEILKCAAEGFKQQEIAEQLHISRRTV
                     NNHLVSINNKLEVNSTISAIIQAIELGIIRVKGY"
     gene            complement(7268..9229)
                     /locus_tag="WMM_RS13625"
                     /old_locus_tag="WMM_01991"
     CDS             complement(7268..9229)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002410798.1"
                     /locus_tag="WMM_RS13625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01991"
                     /product="ATP-binding protein"
                     /protein_id="WP_002404120.1"
                     /transl_table=11
                     /translation="MKEKFVYLLSLFVFLVIALLTIKQNDYLYGSQAVTVVPIIVVLIL
                     FCAVIIFVSKDIKKIRYFAVLTFFTSISLAIGLFPYSFVHPVKSLLISFLPYFVYKFFV
                     TFNLISILSVSKKIDQILFIQSIIVSMLLLLNFEKFIWMVSIVIILDIFGCLFLYFKGK
                     DRLTIRTKKEQVFLIRILVLSLFSLIISTSILSGLVLFLIPITVGIILIKRNEISLDKV
                     SIIINLVIHIICIGIFFIINFYFLRLSILDIYFISIFYCLILFILYLKNWYLSSIEVSR
                     IQQRKKDFQKEKIDFVQTISKEKTLSSVSTLISTIFLQHYEINSYLMVWKDQYQPYILS
                     SSGEFSKLILTNKIIAEFERDSNIFHYHNNKYRKFTFFENKQILGWLLIDREKDFDLAS
                     MKHEEIYDLVGVAGKIIIENERLYDIKQESLKIESLSYDEYVNYEYLNMVQNFHKDFSF
                     FIHDNVLQNILALKKLIESMSTENVETKKLVLETFDTLNKTFRDKIFELYPSTIETVPV
                     SQSIRILCDKFNEGQESIFVHFYCPQEMHLKKEEKFHIYRIIQELITNALKHSRATVVC
                     VYLIQRDFYIECIVQDDGTGFDYSKIKLRGFENKHFGILSINQEVNSLNGKMRVSSVNP
                     HGTKFTITLPIAKEDIDS"
     gene            9689..9826
                     /locus_tag="WMM_RS18400"
                     /old_locus_tag="WMM_01992"
     CDS             9689..9826
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414657.1"
                     /locus_tag="WMM_RS18400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01992"
                     /product="hypothetical protein"
                     /protein_id="WP_002414657.1"
                     /transl_table=11
                     /translation="MTKQNYSKPSIEKIAGFKESTRGLWTGKFRDVFGGRALFQVVIYY
                     "
     gene            10001..11731
                     /locus_tag="WMM_RS13630"
                     /old_locus_tag="WMM_01993"
     CDS             10001..11731
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634142.1"
                     /locus_tag="WMM_RS13630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01993"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_002414658.1"
                     /sec_met_domain="Asn_synthase (E-value: 4.2e-15, bitscore:
                     52.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKRITTDYTNILLVSNTEYSQHTHDQFEIYCISSEYSRIFCNK
                     DQFNYTTTENMLDYLQANISKGVFVLINKEGLFMGGSLFDVSLSWLDSNDELIISDSSA
                     NIALFLNLPISKSALALNLIHNLPYYPFQNIPLWEKVNTIQPFYILKCTTNGILEPIQT
                     WTPPNLENKVESIYSKIRERLLELLSQNTVSYSEISADLSGGVDSATIIYILKALQANV
                     KLYHANADSEWNSDSTWAKLISNDINVIFTSLPSLGSSGKNFEIDRDYSNSVLPDSPLF
                     WADTEGYVESIEHSALTPANATHFTGLGGDELFTPMPANAWSLVRQNKLRSIDLGLRYC
                     LLNRIPISVGTVDLINNNSFKEAVKNEIDKGFGYAKPTRQNSALNWCGPVTVPNWLTKP
                     YRELSYKVLINKLDHTSNSLDSDRSRHQMIESLLFQRHLVTQINNIYGVNGMTWQAPFL
                     DVDIINYSLAIPARYRQDHTVTKSILYNATKGLVSKNIFTRGFKGDYSTSLYKSYKEAV
                     KKHSQQVHQFKLVELGIVDADILISELSMPSALHTRVEAFERLAAVERWLRVALKKNSK
                     "
     aSDomain        11789..12034
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_WMM_RS13635_Stand_Alone_Lasso_RRE.1"
                     /evalue="5.30E-24"
                     /identifier="RREFam002.1"
                     /label="WMM_RS13635"
                     /locus_tag="WMM_RS13635"
                     /protein_end="82"
                     /protein_start="0"
                     /score="75.1"
                     /tool="antismash"
                     /translation="MRKVKRELKIISQDDGAIVLDKSRGIYFQVNASGVSMLEGLSKGL
                     TIEELALQLETSFSLDKAQAETDVAEFMALLKEMKLA"
     gene            11789..12037
                     /locus_tag="WMM_RS13635"
                     /old_locus_tag="WMM_01994"
     CDS             11789..12037
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362859.1"
                     /locus_tag="WMM_RS13635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01994"
                     /product="PqqD family protein"
                     /protein_id="WP_002362859.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.6e-22,
                     bitscore: 75.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.7e-09, bitscore: 33.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKVKRELKIISQDDGAIVLDKSRGIYFQVNASGVSMLEGLSKGL
                     TIEELALQLETSFSLDKAQAETDVAEFMALLKEMKLA"
     gene            12037..14328
                     /locus_tag="WMM_RS13640"
                     /old_locus_tag="WMM_01995"
     CDS             12037..14328
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401909.1"
                     /locus_tag="WMM_RS13640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01995"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_002407163.1"
                     /sec_met_domain="PF13471 (E-value: 1.1e-21, bitscore: 73.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIQLFPEQIDPVSFSARFLARLSLILSAPLNWMSPGRIEKILVK
                     LIKNNPPASEKQVKIARNAVCIVSSRCRSQEGCLRRSLAVVIVLWLQRKSVSWCTGYAQ
                     EPFRAHAWIELNECPIGEPVEVQIYSKAICVPHRSNDILRKESYLKKIKQENIERKKKE
                     SEIVNPEDHTPSVNIRSLFALAKGHNWEFICVGILGLISAALTLAQPNLVANLIDQSNT
                     GIKINSSLGILIVVLILSTILTAVQYYLLQIIGEGVVFKARKSLISHLLRLPIHEYDTR
                     SVGDLLSRVSGDSSKLRMALIQVSIALSSGFLVVVGAAIGMILRDSLLFFMALSTVCVS
                     FIGTIIMSKAIQKASFSAQKELGKLSGDIERDLHAIRTIRATNATDKEEEKSKLQAERL
                     RNIGIRLAKIQAFMTPISNMTLQLSGLIVLGIGGYRVSIGLMSVADLIAFALLLYTMIG
                     PIGQVFNAFGGVGESLGAFARIRELLELALESDYDVTPAIPPSSNLITEETAVYFEKIS
                     FGYNKMKFGSDPKEKEDSMILKEVTLRAEKGKRTAIVGPSGAGKSTLLQLIERFYDPDS
                     GKIFVQGKDYRHYSREELRNFITYVEQDAPVISGTLRDNLLLGNSKISDSNCIEVLEEV
                     NLHHLLDRNSKGLDMQVGESGANLSGGERQRLAMARSLLSSAEIVLLDELTSNLDSLNE
                     LGMKKAVDKLKGKKTVIVVAHRLSTVIDSDIIYVLEHGRVVGSGNHNELIDTVPLYREL
                     AKEQFVDREL"
     gene            14380..15087
                     /locus_tag="WMM_RS13645"
                     /old_locus_tag="WMM_01996"
     CDS             14380..15087
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378542.1"
                     /locus_tag="WMM_RS13645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01996"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_002378542.1"
                     /transl_table=11
                     /translation="MKNIVLSNICKQHKKKNILENITFKAKEGRITAFLGPNGAGKSST
                     LRILLGLDLPLSGTATFGKKKYSNFIFPLQIVGSAFDGIGGTPSRKVKTHLKIIAKSNN
                     IPNKRISEVLDLVDLSNKSHAQLGTLSLGEGQRLGIAIALLGDPQYLVLDEPTNGLDPM
                     GIKWFRNFIRRQADQGKTVLLSSHYLSEIEAIADDVVIINKGQIVVTGELHEVMQNIET
                     LEDVFFLLTEGGN"
     gene            15090..15875
                     /locus_tag="WMM_RS13650"
                     /old_locus_tag="WMM_01997"
     CDS             15090..15875
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362855.1"
                     /locus_tag="WMM_RS13650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01997"
                     /product="ABC transporter permease"
                     /protein_id="WP_002362855.1"
                     /transl_table=11
                     /translation="MSFVKVTYSEFSKLINSRGWWIVFGLVIVLQPLLGLLEADQLLSI
                     GLDATPATHPDLLEAMPPLDYFGFDAALFGVLPIVIWGGISGANEYKNHNLRTTMLYSN
                     KRKELFNAKLLTILISTISISFISIFITVAITHVRLGSLGLNPFILSQTTWKFIGYTTL
                     NWILLTVLSFLIGLLFRNMIVPLIFLVPQIYNLGSYLAEKWPWGEYLPVAAGNFIVATP
                     VKSYPHDPAKGTLILLLWIFFSMLIAFYSFTRSDVGGKY"
     gene            15875..16603
                     /locus_tag="WMM_RS13655"
                     /old_locus_tag="WMM_01998"
     CDS             15875..16603
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634216.1"
                     /locus_tag="WMM_RS13655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01998"
                     /product="ABC transporter permease"
                     /protein_id="WP_002401908.1"
                     /transl_table=11
                     /translation="MVKNILQSEIIKFFSYNWCLFGTVGTILVAPVILFFSGIGNDQPL
                     VTNEILSMSIRNFFLSQAGLVIIAASFFGQEYSNSYLRTTLLTIPARIKLITTKLFLLT
                     VIVWIIGLFSSLICLGIGIIQFNGSFTLSLILEFLIKVIIAMLSWTQITWITVFLTIIT
                     KSHILPIAIMFSLILGLSQMLFAMTAFAKYLPDLATMNLFFSTHTTTLLNGSQGLLVQS
                     IWSLFLSLISFGLIQYRDVR"
     gene            <17431..17568
                     /locus_tag="WMM_RS18790"
                     /pseudo=""
     CDS             <17431..17568
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367047.1"
                     /locus_tag="WMM_RS18790"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="EDIMYRVGHKDSKMTRQVYNYFYPERKERSADQFAQFIEKEKYLF
                     "
     gene            complement(17654..19048)
                     /gene="sufB"
                     /locus_tag="WMM_RS13660"
                     /old_locus_tag="WMM_01999"
     CDS             complement(17654..19048)
                     /GO_function="GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356769.1"
                     /locus_tag="WMM_RS13660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_01999"
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="WP_002356769.1"
                     /transl_table=11
                     /translation="MSTVPELEEYKFGFHDDVEPVFSTGDGLTEDVVREISRVKGEPEW
                     MLDFRLKSLEQFNKMPMQEWGPDLSDIDFSKIKYYQKPSDKPARDWDDVPDKIKETFEK
                     IGIPEAERAYLAGASAQYESEVVYHNMKEEFEKLGIIFTDTDSALKEYPDLFKEYFSKL
                     VPPTDNKLAALNSAVWSGGTFIYVPKGVRVDVPLQTYFRINAENTGQFERTLIIVDEGA
                     SVHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKAYEGA
                     TVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAPNTSSS
                     IVSKSIAKDGGEVNYRGQVTFGKDSAGSISHIECDTIIMDEKSKSDTIPFNEIHNSQVS
                     LEHEAKVSKISEEQLYYLMSRGLSEAEATEMIVMGFVEPFTKELPMEYAVELNRLISYE
                     MEGSVG"
     gene            complement(19067..19534)
                     /locus_tag="WMM_RS13665"
                     /old_locus_tag="WMM_02000"
     CDS             complement(19067..19534)
                     /GO_function="GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362181.1"
                     /locus_tag="WMM_RS13665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_02000"
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="WP_002356768.1"
                     /transl_table=11
                     /translation="MALSKLDNLYRQVILDHSSHPHHHGTLDASSQTIELNNPTCGDVI
                     ELDVAIEDGVIKDIAFQGSGCSISTASASMMTDAVLGKTIAEATALAEDFSQLVQGNEV
                     AEDEKLGDAAMLSGVAKFPARIKCATLAWKALEQAVANNGQGEAGHLHCEK"
     gene            complement(19521..20756)
                     /locus_tag="WMM_RS13670"
                     /old_locus_tag="WMM_02001"
     CDS             complement(19521..20756)
                     /EC_number="2.8.1.7"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (23-395). E-value: 4.6e-162.
                     Score: 531.1. Matches aSDomain:
                     nrpspksdomains_WMM_RS13670_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010712667.1"
                     /locus_tag="WMM_RS13670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_02001"
                     /product="cysteine desulfurase"
                     /protein_id="WP_002372178.1"
                     /sec_met_domain="Aminotran_5 (E-value: 3e-162, bitscore:
                     536.1, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.8e-10, bitscore:
                     36.8, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 7.3e-10,
                     bitscore: 35.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMDAATIRQSFPILFQEVNDEPLVYLDNAATTQKPTAVLDVLRHY
                     YETDNANVHRGVHTLAERATKDYEASREKVRQFIHAKETAEVLFTRGTTTSLNWIAKSY
                     GDLAVTAGDEIVISYMEHHSNIIPWQQLAQRTGAILKYIDVTEDGFLDMASARQQITEK
                     TKIVSIAHVSNVLGVINPIEELTQLAHQNGAVMVVDGAQAVPHMPVDVQAIDADFYAFS
                     GHKMCGPTGIGVLYGKRHLLEQMEPVEFGGEMIDFVHLQESTWKELPWKFEAGTPNIAG
                     AIALGAAIDYLTEIGLEAIHQHEAALVHYVLPKLQAIEGLTIYGPQNPKDHTGVIAFNI
                     EGLHPHDVATALDMEGVAVRAGHHCAQPLLNYLSVPATARASFYLYNTKEDADRLVEAI
                     KATKEFFQHGTF"
     aSDomain        complement(19572..20687)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_WMM_RS13670_Aminotran_5.1"
                     /evalue="4.60E-162"
                     /label="WMM_RS13670_Aminotran_5.1"
                     /locus_tag="WMM_RS13670"
                     /protein_end="395"
                     /protein_start="23"
                     /score="531.1"
                     /tool="antismash"
                     /translation="VYLDNAATTQKPTAVLDVLRHYYETDNANVHRGVHTLAERATKDY
                     EASREKVRQFIHAKETAEVLFTRGTTTSLNWIAKSYGDLAVTAGDEIVISYMEHHSNII
                     PWQQLAQRTGAILKYIDVTEDGFLDMASARQQITEKTKIVSIAHVSNVLGVINPIEELT
                     QLAHQNGAVMVVDGAQAVPHMPVDVQAIDADFYAFSGHKMCGPTGIGVLYGKRHLLEQM
                     EPVEFGGEMIDFVHLQESTWKELPWKFEAGTPNIAGAIALGAAIDYLTEIGLEAIHQHE
                     AALVHYVLPKLQAIEGLTIYGPQNPKDHTGVIAFNIEGLHPHDVATALDMEGVAVRAGH
                     HCAQPLLNYLSVPATARASFYLYNTKEDADRL"
     gene            complement(20753..22039)
                     /gene="sufD"
                     /locus_tag="WMM_RS13675"
                     /old_locus_tag="WMM_02002"
     CDS             complement(20753..22039)
                     /GO_function="GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634218.1"
                     /locus_tag="WMM_RS13675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_02002"
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="WP_002364433.1"
                     /transl_table=11
                     /translation="MKKVNLMDYLDEVTAFSLEHEEPAWMTELRTTALRNADESELPHI
                     DRVKFHRWPLLNVHMESYVPSEGNVASFDQMKDNPLIVQQGSFHAFEQLPASLAEQGVI
                     FTDIFTALQEHPELVKEYYMTKAVLPEEDKLTAAHAAFMNSGVFLYVPKNVVIEEPIES
                     LFIQDSDSNQPFFKHVLIVADNHSEFSYLERFQSTGHHAEKASGNIVVEVIAKDGAKVK
                     YSAVDQLGQTVTTYMNRRGYIMRDASVDWALGVMNDGDVVADFDSDLVGEGAHSEVKVV
                     AISAGKQTQGIDTRVTNKAPHSIGHILQHGVIRERGTLTFNGIGHILKGAKGADAQQES
                     RVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLRKEEAERLVIR
                     GFLGSVITAIPVKEVQNEFVEVIEGKLNA"
     gene            complement(22054..22824)
                     /gene="sufC"
                     /locus_tag="WMM_RS13680"
                     /old_locus_tag="WMM_02003"
     CDS             complement(22054..22824)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317772.1"
                     /locus_tag="WMM_RS13680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_02003"
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="WP_002356763.1"
                     /transl_table=11
                     /translation="MSVLEIKNLHVSIEDKKILKGVDLTINTGEIHAIMGPNGTGKSTL
                     SAAIMGNPNYEVTEGEILFDGVNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMRAA
                     INAKRDEDNKMSVMQFLKKLDSKMELLNMPEEMAERYLNEGFSGGEKKRNEILQLLMLE
                     PTFAILDEIDSGLDIDALKVVSKGVNEMRGENFGALIITHYQRLLNYITPDVVHIMMEG
                     RVVKTGGADLAKRLETEGYAGISQELGIDYKEEA"
     misc_feature    22882..22900
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 28.04"
                     /tool="antismash"
     misc_feature    22883..22899
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.37"
                     /tool="antismash"
     misc_feature    complement(23060..23071)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.78"
                     /tool="antismash"
     gene            complement(23194..23751)
                     /gene="frr"
                     /locus_tag="WMM_RS13685"
                     /old_locus_tag="WMM_02004"
     CDS             complement(23194..23751)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="frr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /locus_tag="WMM_RS13685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_02004"
                     /product="ribosome recycling factor"
                     /protein_id="WP_002356762.1"
                     /transl_table=11
                     /translation="MSKEVLATAKEKMTKAEESLRRELGQIRAGRANASLLDRIQVEYY
                     GAPTPVNQLASINIPEARVLMITPFDKNSIADIEKAIQMSDIGISPTNDGNVIRLVIPQ
                     LTEERRKELAKDVKKEAENSKVAVRNVRRDAMDELKKAQKNGDITEDELRSFEKDVQKL
                     TDDSIKNIDAITAEKEQELLEV"
     misc_feature    24151..24164
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
ORIGIN
        1 gaaaaaaggc cctcagacaa atctgtcaag tgcctttttt cggtttctct gcattcgctt
       61 ctctattaag tatactcgtt ttttgtaaaa aaacaatctt gtttcttttc taaaaagagc
      121 taagaagagc ttgaagcaaa aatcacttta gatttttgct tcaagcttaa acgctgataa
      181 gtggcggaaa cagtttatcc taatcattct gtccgccctt ttcattatta ttccacttct
      241 gatgttgtgt tcatcaaaat agaaagtgtg ctttctaatt cttctttgcg tacttccaac
      301 atttcaccag tacgtttgat tttgacttct accacaccat cgactgcttt tttaccgact
      361 gtgatacgga ttggacaacc aattaaatca gcatcagcaa attttacgcc tgcgcgctca
      421 ttgcggtcat caactaatac ttcgtagccc gcttcggtca tcattgcttc aacttcttgt
      481 gatagttttg tttggtactc atctttcaca ttcatttgga ccacgtgtaa atcaaatggc
      541 gcaattcctg ttggccaatt aataccgcgc tcgtctgcat tttgttcaac gattgctgaa
      601 agtaaacgac taacgccgat gccatagcaa cccatgatca ctgatttttc acgaccgttt
      661 tcatctaaaa ctgttgcgcc catagcatca ctgtaacgcg ttcctaattt aaagatatga
      721 ccaatttcga ttcctttagt aaaggctaag acaccattgc catcaggaga aggatcgcct
      781 tcttgaacaa aacgtaaatc ttcgtaacta attggttgga aatcacgatc tggatttaca
      841 tttgtcaaat gatagccatc ttcgttagcc ccaacaatgg cgttggctaa atcttgaaca
      901 gctaaatctg cataaatttt aacatcttcg gaaacattga ctggaccaat tgaaccaaag
      961 cccgctccta agacacggcg agcatcttct tctgttgctt catctaagaa atcagcgcct
     1021 aagaagtttt tcaatttgac gtcattgaca tcatgatcgc cacgaaccaa gaccattact
     1081 ggctcttcat cggcaataaa tagtactgat ttaataatac gttgtggctc aacttcaaag
     1141 aagtttgcca cttcggcaat tgtacccact tctggtgttg caattttttc taaatctaat
     1201 tgtgtttcat gtgatttttt cggcgtataa agacttgttg ccatttctaa attggcagca
     1261 taatcacttt ctgttgaata acaaatagta tcttccccaa tttcagaaat cgccataaat
     1321 tctttagaat ctttaccacc catggcacca ccgtccccaa taatggcacg gaattctagt
     1381 ccacagcgtt caaaaatgcg tgagtaagct ttttcgtaat cacggtatga ttgatctaaa
     1441 ctagcttcat cggcatggaa agaatagcca tctttcatga taaattcacg gcctcttaat
     1501 aagccagaac gtgggcgttt ttcatcacga tattttgttt gaatttggta taaattcaaa
     1561 ggtaatcgtt tgtaagaatt aatttcatca cgaattaatt ctgtgaaggt ttcttcatgc
     1621 gttgggccta agatatagtc acggtcattg cgatctttta agcgatacaa gttaggtcca
     1681 taagtttcat aacggcctga ttctttccaa agttctgctg gtaataacgc aggcattaac
     1741 atttcaactg catcaatttt ctcaaattct tctcgcataa tcgtttttaa tttttctaaa
     1801 acacgattgg ctaaaggtaa ataagaatag atccctgcag cgacttgacg aatatagcct
     1861 gcgcgcaaca gaatttgatg acttaagact tctgcatcat ttggtacttc tcttaacgtt
     1921 ggaattaaca tttttgactg tttcattaaa actctcctct attttaaaat caactatttt
     1981 tgatttcttt acacactttt ttacttaagc tttctcctta aaagaaaaag cgttgaatat
     2041 cgttccaagt aactaacacc attaacacca tgacaaaccc aaagccaatt aacgtaatga
     2101 tgccttcttt ttcaggacta attggttttc cacgtacacc ttcaataatg tttaagacaa
     2161 ttttcccgcc atctaaagct gggatcggca acaaattaat aatccctaag ttcattgaca
     2221 acatggccat taagaataca actgtactta ctccagcatt ggatgcttct tccgataact
     2281 taaacatcat gactggccca cctagtttgt ttaaactaaa gcctgtgaat agtgagccga
     2341 gtgctttaaa aatctgtgtc gtactattta aagtatcctg aataccgccc atcaattttg
     2401 acggtaaatc ggttttcata taaggataaa cgccgacttt accaatcgtt tgtttttcca
     2461 ctttttgttt ttctggtgtc actgttagtt gctcttcttt gccgttacgc tcaactacga
     2521 acgttaacgg cttttcgggg ttcttctgca caatggttgt aaaatcttcg tattttttga
     2581 ttttttgatt attaatcgat aagactttat cattttcttt caacccagct tctgcggctg
     2641 ggccattagg aatcacttgt ccaatttgat tcgtgtttaa atcagtaacg cctccttgta
     2701 gaaagaccgc taacgtaaac agaataaacc ctaagataaa gttattcatg ggtcccgcaa
     2761 agttcgtcaa aatgcgttgc gataatttcg ctgattgaaa ttgaacgtca agtggcgcaa
     2821 tccgcacctc ggttccatca ctttcaataa tcgttgcatc atggtcaact ttataaacgg
     2881 tttcttcttc ctcgtttcca ttgacatagc ccttgatgaa taattctttt tcaagatcaa
     2941 aatcaacgac ttccatcgga atactatgag gtaattgtac ttttttactt gtattaattt
     3001 taaccacatt acccacggca tttaactcaa cagatagagg catacctggt gtgatttctg
     3061 tcatgtcttc gcccatccca gccattcgca catagccacc aatcggcaat aagcgaatcg
     3121 tataagtggt gccatctttt ccacgatgcg caaaaatctt tggtcccatt ccgattgcaa
     3181 actcacgaac taaaataccc gctcgttttg caaaataaaa gtggccaaat tcatgtacga
     3241 ggacaagaat accgaagaca ataatgaatg tgataattgt tttcatagat gtccttcttc
     3301 cttcattcac tgacgttcag tgctttttat tattacatgg gaaagtctcg taaaacttgc
     3361 tctgttccct tcccgataaa ccagtgcaac tgtttactga gaacagtcgc cactgttagt
     3421 gaacaaatct ttccttatgt aagacaagtt ttattttagc atattcagtc ataaataacc
     3481 attggacttg accacttcgc ctagatattt tgtgtttttt tagaaaactc tataaatgag
     3541 aggaattgat tactacgacc agtatttttt taaagacctt caacaatagt agctaacttt
     3601 agagcctaaa cttttccgac agtttgtcgt attttatcaa cacgctgatt gacatgtgct
     3661 accatgaaag tattaatagt aattttaggg ggaatgaatc aatgtatgga gaattacatg
     3721 gtaaagtggc cgttgtcact ggtgcagcta cgggtttagg attatttatt actctgcgtt
     3781 atatcttaga gggcatgaat gttgttgctg actatgtcgg tgagctgcct aaagaatttg
     3841 aagatgtcca agccaagcac gcagaccgcg taaaattcgt gaaggctgat gtctctaatg
     3901 aagaagatat taaagcgtta gctgaaaccg ctttaaaaga gtttggtcat gttgacattt
     3961 gggtaaataa cgccggtgtg gaggcttctt ttccgacaat tgatatgcca ttaaaagaat
     4021 ggcaacgtgt cattgatgtc aatttaaacg gtgtcttttt gggttctaga gaagcactcc
     4081 gaatatttag agatcaaaaa atcaaagggt caatcattaa tatgtcctcc gttcaccaaa
     4141 gaattccttg gccaacgttc gctcactatg cggcaagtaa aggcgcaacc gaaatgttca
     4201 cgaaaacaat cgctttggaa tatgcggaat atggtattcg tgccaactgt attgcgcctg
     4261 gagcgattaa cacacctatt aatgctgaaa aattttccga tcccgaacag ttaaaacaaa
     4321 caacgagcat ggttcctatg ggcattattg gtaaaccaaa tcaagtagct gctgcggccg
     4381 cttggttagc ttctgatgaa tcctcatacg taaccggaac aacactcttt gtagatggcg
     4441 ggatgtctct atacccttcg ttccaacacg gagctggtta aaaagtagtc tgcaacaaaa
     4501 attctctatg aatttttgtt gcagactttg tactatcaca cacaaaatct attcaggagg
     4561 cttaccatga aactagtcaa aaatgttctt ttaattttaa ttggtttagt tattatcggg
     4621 attggcgcat ccactttaag agtggcaggt ttaggagttg atcctttcac tgctatgaat
     4681 atcggacttt cttcgatgtt tggtatgcaa ttaggcattt ttcaaattat tgtcaatgcg
     4741 tttattttat tctatgtcta tttaaaaaac aaaaaagcca ttggtctagg aactatttta
     4801 aatatgcttt tagtaggaat tttgattcaa cagatttcta cttggcttca accttacgcc
     4861 aatagtttag gaggctcaac aattggcaaa ctactttctt tattcgtcgg agtcctgatt
     4921 tttacatttg gctgcgcctt atacatggct acagatcaag gcgaatcccc ctatgatgcg
     4981 attgcgccaa ccatctgtca acaaatcaac aaaccttacg cttctgttcg aaaagcacaa
     5041 gatttgttgg tcctattaat tggctttatt gctggtggtc caattgggat tggtacaatt
     5101 atttgtgcat ttggtgctgg cccacttatt agtttctgga acaagttact tcaaccttta
     5161 gtaaaataat tttttaacta aaatataaga aaaagcgatg actccataga gattttcttc
     5221 tcgagtcatc gcttttttat ttgtgcttct ttgaagaagc atgattagta tgtttcttgt
     5281 ttggctttcc gttgttgttt tagttgatta tttgttggta gagtgaaaaa ctagccgaca
     5341 gagccttcca gcaaagggtt agttttttta agagcttctg ataagctcta atcgttggta
     5401 tgacagcatt attctttttc ttagaatgtt gtgaaatacc agtgattttt ttcaattgta
     5461 gttagttttg atttagtttc aaaccgtttc aactataaaa atatggatac ttttggatag
     5521 tttttagtaa gaaaaatgcg agctaaacga ataactataa caaagtcagt tttcatgaat
     5581 aaattaatta cgacaaaaga gttatttaca aacaagaacg tacgttttta taataaacct
     5641 agtgttacag tttaagtgca acactaaatt attctacttg aaaggacgat aagtatttgt
     5701 tattgattta aattctttaa gcgaaataat tttattgtcg ttcactttga aaagagtaac
     5761 accagtaaaa taatgctcct cgcctttata tttgtacttt ttgaatttgt acatttcttc
     5821 ccctttcaat gtgttcaatt gttttatagt acaattatac taaatgatat caccgataaa
     5881 aaagccaata gcccgcacat tgccatcact ggacccactg taaacggaaa atcttacttg
     5941 gcaaagttca ttttcttcct ctccgtttta atgaatggaa aaggcttgta cgttgaccct
     6001 aaatctgagt tttttaatcg gattatggag gtgatcaatc atccacttta ttacgattca
     6061 attctcaaaa actcaagcag atggaaaaac agtcacttac actaatccta tagctatcaa
     6121 cataggctat gattatcgtt atgcgtatgg caatatgttt tatgctcaaa ttgttaaaca
     6181 atacatcact tctatttcca acaacaatag tcaagggaat tcagctattg taaaagcagc
     6241 acttaaagaa ttgaatgaag gaatacataa gggtggaacg aaatattggc aatggtatgg
     6301 ctttaatgga cgtgtagaat ggtgcgctat ttttgtttct tataatgctg aaaaagctgg
     6361 agttaaaatg gaacattttg cctattgccc aactggtatt gaaaatttta aagcgaataa
     6421 ccaatggttt aggaaaggaa gtttgcctaa aaatgggaat atcatctttt ttgattggga
     6481 tggtgattct atcagttatt acgttgggat tgttgagaaa gtagaaaatg aagttgttta
     6541 cacaattgaa gagaattcag gaaacaaaat tgctaaacta agttatgaaa aaatagccct
     6601 tatatcatgg gttatggtat tccgtaaaca gcatatcttt ctgaataaat gtttgataat
     6661 ttcaacattt tttagtatca atatcctttt actctaataa ttcccaattc aatagcttga
     6721 ataattgcag aaatggttga atttacctct agcttattat ttatggatac aagatgatta
     6781 tttactgttc ttctactgat atgaagttgt tctgctatct cctgctgctt aaaaccttct
     6841 gcagcacatt ttagtatctc tttttctcgt ttactaagaa catctaatgt actttggcac
     6901 ttgggtagca gatcagttcc atgatgtatt ttttgtaaat catcatacaa ttcttcaatt
     6961 gttacatttt tatttaatag tccccatgct ccagatttta ttgcttcatt cttgtattca
     7021 attaaatcaa aacctgataa aaaaactatt ttttgatttg gaaattttcc aataatttct
     7081 ttagatattt caaatccact taactctcca atatggatat ccaataatgc taaatctggt
     7141 tgctcatttt ttagtttatt taaaaaaaat tctggattag taaaactagt aattgagaca
     7201 tccattggtt gaaatgcaat ttcaagactt ttagagaaaa gtgcatgatc gtctaataaa
     7261 tatactttca tgaatctata tcctcctttg caatcggtaa agttattgta aattttgtac
     7321 catgtggatt tacagatgat actctcattt ttccatttaa tgaattaacc tcttgattta
     7381 ttgatagaat accaaaatgt ttattttcaa atcctctaag ttttattttg ctataatcaa
     7441 agcctgtgcc atcatcttgt acaatacatt ctatataaaa gtccctttga atgagataaa
     7501 cacaaactac tgttgctcga gagtgtttta gagcattagt tattaactct tgtataattc
     7561 gataaatatg aaatttctct tcttttttta gatgcatttc ttgtggacaa taaaaatgaa
     7621 caaatataga ttcttgtccc tcattgaatt tatcacaaag aattcgaatg ctttgcgaca
     7681 caggcactgt ttcaatcgtc gaaggatata attcaaatat cttgtctcta aaagttttat
     7741 ttaaagtatc aaaagtttct aatactaatt tctttgtttc tacattttca gtagacatag
     7801 attcgattag tttttttaaa gccaaaatat tttgtaaaac attgtcatga ataaaaaatg
     7861 aaaaatcttt atgaaaattt tgcaccatgt ttaaatattc ataattcacg tattcatcat
     7921 aagataaact ttctattttt aatgattctt gtttaatatc atataagcgt tcattttcaa
     7981 taattatttt accagcaaca ccaactaaat catatatttc ttcatgtttc atactcgcca
     8041 agtcaaagtc tttttctcta tctatgagta accaacctaa aatttgttta ttctcaaaaa
     8101 aagtgaattt tctatattta ttgttgtgat aatggaatat gttagagtcg cgttcaaatt
     8161 cagcaataat tttattcgtt aaaatcagtt tagaaaattc tcctgagcta gacaaaatat
     8221 atggttggta ttgatctttc caaaccatta aataactatt tatttcgtaa tgttgcaaaa
     8281 agattgtact aattaaagta cttactgaag acaaagtctt ttctttactg atagtttgta
     8341 caaaatcgat cttttctttt tggaaatctt tctttctttg ttgaattcgg ctcacctcaa
     8401 tactactcaa ataccaattc ttcaaataaa ggataaacaa aatcagacaa taaaaaatag
     8461 aaataaaata gatatcaagt attgataatc gaagaaaata aaaattaata atgaagaaga
     8521 ttcctataca aataatatgg ataactaaat ttataataat tgatacttta tctaagctaa
     8581 tttcattacg ttttattaaa ataattccga ctgtgattgg gataagaaaa agaaccaacc
     8641 cacttaaaat agaagtagaa ataattaacg aaaatagcga taaaactagt attcgaatta
     8701 gaaaaacttg ttcttttttt gttcgaatgg ttagtcgatc ttttccttta aaatataaaa
     8761 ataaacaacc aaaaatatcc aaaatgatta ctatactcac catccatatg aatttttcaa
     8821 aattaagaag cagtaacatg gatacaataa tagattgtat aaataaaatt tgatcaattt
     8881 ttttagaaac agataaaatc gaaattaagt taaaagtgac aaaaaactta taaacaaagt
     8941 aaggtaaaaa tgaaattagc agggatttga caggatgcac aaaagaataa ggaaataatc
     9001 ctattgctaa ggaaatggaa gtaaaaaaag taagtacagc gaagtatcta atctttttaa
     9061 tatctttaga gacaaaaata ataactgcgc aaaaaagaat aagtacaaca ataatcggta
     9121 caacagttac tgcttgcgat ccatacaaat agtcattctg cttaatagta agtagagcta
     9181 tcactaagaa tacaaataag gataacaaat aaacaaattt ttctttcata cacttttctc
     9241 caatctaagt attccttgaa tattctacag ttcttcgttt ttttaaagat actaattttg
     9301 aatttatagt ttgaataaaa ttttctaata tcccactaat gtattaaaca acacagattt
     9361 tattcatact ccactctgtg tattttttaa tgatatcttc atcttactct ttcttaaata
     9421 attgcacaat atactcatta caaataatcc ctttttttgt atgattaata tataagttga
     9481 tagaaaaaag ctacttaacc ttaaaaacaa cgaattaaga gtaatttatt tcctgattct
     9541 agctgttttg ttctattgtt taactaaaat atagatgtca agaatttcct atactcattt
     9601 ttcagtacta agtaatcaag gtaactattt tctaatttac ttgaattaga aaatttagta
     9661 tacaccaact atgaaggagg tgaactctat gacaaagcaa aattacagta aaccatcaat
     9721 tgaaaaaatt gcaggtttta aagaatctac tcgtggtctt tggacaggta aatttagaga
     9781 tgtatttggt ggacgcgctc ttttccaagt tgtaatttat tactaggaca gaaaaatggg
     9841 aaataattat gctagcggtc atcgaattac ataattatgc cattggtcat cgaattacat
     9901 aattcgatga cctttttagt aatccgcata gtctttattt agggaggtgc ttctaattat
     9961 tgtaaacaaa tcaaatatct ctatatcctc aaaaaaattg atgtttcaaa aacgtattac
    10021 tacagactac actaatatac tgctggtatc caataccgag tactctcaac atacacacga
    10081 tcaatttgaa atttactgta tttcttctga atattcaaga atattttgca ataaagacca
    10141 atttaactac actactacag aaaacatgtt agattatctt caagcaaata tttctaaagg
    10201 cgtatttgtt ttaataaata aagaagggct atttatggga ggatcattat ttgatgtttc
    10261 tctttcatgg ttggactcaa atgatgaact aatcattagt gattcatcag caaatatcgc
    10321 attatttctt aatttaccaa tttctaaatc ggctcttgca ttaaatctaa ttcataattt
    10381 accatactac ccattccaaa atattccctt atgggaaaaa gtaaacacga tccaaccatt
    10441 ctatattttg aaatgtacaa caaatggaat cttagaaccc atacaaactt ggacacctcc
    10501 aaacttagaa aacaaagtcg aatctattta ttcaaaaata cgagagcggc ttctagaatt
    10561 gcttagtcaa aatacagtta gttactctga gatatccgct gacctttcgg gtggagttga
    10621 ttcagcaaca attatttata tcttaaaagc gcttcaagct aatgttaaac tttatcacgc
    10681 aaatgctgat agtgaatgga atagcgattc tacatgggca aaattaatct caaacgatat
    10741 caacgtcata tttacttcat taccttcttt aggtagctcg ggaaaaaatt ttgaaattga
    10801 tagagattac tcaaactcag tgttaccaga ttctccatta ttttgggcag atacagaggg
    10861 atatgttgaa tccatagaac attcagcatt aactcccgcc aatgccactc attttacagg
    10921 tcttggcggg gatgaattat tcactcctat gcctgctaac gcatggtctc ttgtacgaca
    10981 aaataaatta cgcagtatag acttaggctt acgatattgt ttactaaatc ggattcctat
    11041 ttcagttggg acagtagatc taataaataa taattccttt aaggaagctg taaaaaatga
    11101 aatagacaaa ggatttggtt atgctaaacc aactcgtcaa aactccgcac tcaactggtg
    11161 cggtccagtc acggtaccta attggcttac gaagccttac cgagaattaa gttataaagt
    11221 tctaataaat aaattagatc acacatcgaa ttctttagat tccgatcgtt ctcgacacca
    11281 aatgatcgag tctctacttt ttcaaagaca tttggtaact cagattaaca acatatatgg
    11341 tgttaatggt atgacttggc aagctccctt tttagatgtc gatattatta attactcgtt
    11401 agctatacca gctcgttaca gacaagatca cactgtaaca aaatcgattt tatataatgc
    11461 cactaaagga cttgtttcaa aaaatatttt tacacgtgga tttaaaggag actattccac
    11521 aagtttgtat aaaagttaca aagaagccgt aaaaaagcat tcccagcaag tgcaccaatt
    11581 caaattagtt gaattaggaa ttgtagatgc agatatacta atttctgaat tatcaatgcc
    11641 ttctgctcta catactagag ttgaagcctt tgagagatta gcagctgttg aacgctggct
    11701 tcgtgtagct ttaaaaaaga actcaaaata aaaggaagtt gctgcttacc tagttgtagt
    11761 tattttctaa aaaggaggag taatattaat gagaaaagta aaaagagagt tgaaaattat
    11821 tagccaagat gatggtgcaa ttgttttgga taaaagtaga ggaatttatt tccaagtaaa
    11881 tgcttctgga gtttctatgt tagaaggttt gagtaaagga ttgacgatag aagagttagc
    11941 actacaattg gaaacttcat tttctctaga taaagctcaa gcggaaacag atgttgccga
    12001 gtttatggct cttttgaagg agatgaaact tgcataatga atatccaact ttttccagaa
    12061 caaatagatc cggtatcttt tagtgcaaga tttctggctc gtttgagttt aatactatct
    12121 gcaccgctta attggatgtc ccctgggaga attgaaaaaa tattggtgaa gctaataaaa
    12181 aacaatcctc ccgcatcaga aaaacaggta aaaattgcgc gaaacgcagt gtgtatcgta
    12241 agtagtagat gtagaagtca agaaggatgc cttagacgat cgcttgctgt tgtaatagta
    12301 ctatggctac aacgtaaatc agtaagttgg tgtactgggt atgcacaaga gccatttaga
    12361 gcacatgcat ggatagaatt gaatgaatgc cctattggag aacccgtaga agttcaaata
    12421 tattctaaag caatatgtgt tccacaccgt tcaaatgata ttctcagaaa ggaatcgtat
    12481 ttgaaaaaaa taaaacaaga aaatatagaa cgtaaaaaga aggagtccga aattgttaat
    12541 cctgaagacc atacgccctc agtaaatatt agatccctgt ttgcattagc aaaagggcat
    12601 aattgggaat tcatttgcgt tggaatatta ggattaatca gtgcagcttt aaccctcgct
    12661 caacctaacc ttgttgctaa tttaattgat caatcaaata caggaattaa gattaattca
    12721 agtttaggaa ttctcattgt agtattgata ctatctacga ttttaacggc tgttcaatat
    12781 tatctgctac aaataattgg tgaaggggtc gtttttaaag cgcgaaaaag tttaattagt
    12841 catttattaa gattgccaat ccacgagtac gatacaagaa gtgtaggtga tttactaagc
    12901 agggttagtg gtgactcttc taaattgaga atggctttaa tacaagtgag tattgcgctc
    12961 agtagtggtt ttttagttgt tgttggggca gctatcggga tgattttgag agattccttg
    13021 ctatttttta tggctctttc aacagtttgt gtatctttta ttggaaccat cattatgagt
    13081 aaagctatac aaaaggctag tttttctgca caaaaagagt tgggaaaatt gagtggagat
    13141 atcgaacgtg atttacatgc tatcagaaca attcgtgcaa caaacgcaac agacaaggag
    13201 gaagaaaaat ctaaattgca agcagaacga ttgcgtaata ttggaataag attagctaaa
    13261 atacaagcat tcatgactcc tatttctaat atgactctgc aactatctgg tctaattgta
    13321 ctgggaatag gtggataccg tgtgtctatt ggtttaatgt ctgttgctga cttaattgca
    13381 ttcgctttgc tactctatac aatgattggt ccgataggac aagttttcaa tgccttcggg
    13441 ggcgttggtg aatcactcgg tgcttttgct agaattcgcg aattattaga acttgcatta
    13501 gaaagtgact atgatgtcac tcccgctatt ccccccagtt caaatttaat aactgaggaa
    13561 actgcagtct attttgaaaa aatcagcttt ggatataata aaatgaaatt tggttctgat
    13621 cctaaggaaa aagaagatag catgattctc aaagaagtaa cgttacgtgc agaaaaggga
    13681 aaaagaactg caattgtagg tccctcaggc gcaggaaaaa gcacattgct tcaattaatt
    13741 gaaagatttt atgatcctga cagtggcaag atattcgttc aaggaaagga ttataggcat
    13801 tatagcagag aggagcttcg gaacttcatc acttatgttg aacaagacgc tcctgttata
    13861 tctgggacac tacgcgacaa cctactttta ggaaattcta aaatatctga ttcaaactgc
    13921 atcgaagtat tggaagaagt caatcttcat catttattag atagaaattc taaaggactt
    13981 gatatgcagg ttggagaatc tggtgcaaac ctctctggtg gagaaagaca acgtttggct
    14041 atggcacgct ctcttttatc atctgcagaa attgtgttac ttgacgaatt aacctctaac
    14101 ttggacagct taaatgaatt aggaatgaaa aaggcagtgg ataaattaaa agggaaaaaa
    14161 acagttatcg ttgtagcaca tcgtctatcc acagtaattg attctgatat catttatgtc
    14221 cttgaacatg gtagagttgt cggttcagga aatcataatg agctaattga tacagttcca
    14281 ctttatcgag aattagcgaa agaacaattt gtggatagag aactgtaaat ttttaattta
    14341 agaacaaatt aaataaaaaa atttaaagga gccatactat tgaaaaatat tgtcctttca
    14401 aatatatgta aacaacataa aaagaaaaat atactagaaa atataacttt taaggctaaa
    14461 gaaggacgca taacagcttt tcttggacct aacggagctg gaaagagctc tacacttaga
    14521 atacttctcg gtttagacct gcctttatca ggaacagcca ctttcggtaa aaaaaagtat
    14581 agtaatttca tctttccatt acaaattgtc ggatcggcat ttgatgggat tggcggaact
    14641 ccatcaagaa aagttaaaac acatctgaaa atcattgcaa aaagtaacaa catcccgaat
    14701 aaacgtattt cagaagtctt agatcttgtc gacctatcaa ataaaagtca tgcacaactt
    14761 ggaaccttat ctttaggtga agggcaaaga ttaggtattg ctattgctct gctaggagat
    14821 ccccaatatc tggttcttga tgaaccaaca aatggtttag atcccatggg aataaaatgg
    14881 tttagaaatt ttattcgtag acaagctgat caaggaaaaa cagtattact ctcctcacac
    14941 tacctttctg aaatcgaagc tattgcggat gacgttgtta tcattaacaa aggtcagatt
    15001 gttgttactg gtgaacttca tgaagtgatg caaaatattg aaacattaga agatgtattc
    15061 tttctactta ctgagggagg aaattaatca tgagttttgt taaagtaact tattccgaat
    15121 tttctaaact gataaatagt cgtggatggt ggatagtttt tggattagta atcgtgcttc
    15181 aacccttact tggattatta gaagcggatc aattactttc cataggatta gatgcaactc
    15241 ctgcaacaca tccagattta ttagaagcta tgcctccatt agattatttt ggttttgatg
    15301 ccgctctatt tggagtactt ccaattgtaa tatggggcgg aattagcgga gctaatgaat
    15361 ataaaaatca taatttacgt acaaccatgt tatatagtaa taagcgtaaa gaacttttta
    15421 atgccaaact actaactatt ttgatttcta ctatatcaat ttcattcatt tcaatattta
    15481 ttaccgttgc gattacacat gttagattag gtagtttagg attgaatcca ttcattttaa
    15541 gtcaaactac ttggaagttt attggctaca ctacattaaa ttggatatta ttaacggttt
    15601 tatccttttt gattggctta ctttttagaa atatgattgt tccgttgata tttctagttc
    15661 ctcaaatcta taatcttgga agttatctag cagagaaatg gccctggggg gaatatctac
    15721 ccgtagcagc aggaaatttt attgttgcta ctccggttaa atcttatcct catgatccag
    15781 caaaaggtac attgatactt cttctatgga tatttttttc tatgttaata gcattctatt
    15841 cgtttactcg tagcgacgtg ggaggaaaat attgatggtt aaaaatattc ttcaaagtga
    15901 aataatcaaa tttttctctt ataattggtg cttattcggc acagtcggaa ccattttagt
    15961 agctcctgta atattatttt tttctggaat tggaaatgat caacctttgg taaccaatga
    16021 gatattatcc atgagtatac gtaatttttt tttgagtcaa gcgggacttg ttataatagc
    16081 tgctagtttc ttcggtcaag aatattcaaa ttcatattta cgtacaactt tactaacgat
    16141 acctgctcga ataaaactca ttactactaa actatttctt ctaacagtta tcgtatggat
    16201 tattggttta ttctccagtt taatttgctt aggaattggt attatccaat ttaacggctc
    16261 ttttactctc tctttaattc ttgaattttt gattaaagtg attattgcaa tgttaagttg
    16321 gacgcaaata acttggatta cagtcttttt gaccatcatt accaaatcac atattttacc
    16381 aattgcaata atgttctctc ttattcttgg attaagtcaa atgttattcg caatgactgc
    16441 atttgcaaaa tacttacccg atttagcaac catgaatctt tttttttcaa cccatacaac
    16501 tactttatta aatggttctc agggtttatt agttcaaagt atctggtcct tatttcttag
    16561 tctaatttca tttggattga ttcaatatcg tgatgttcga tgactacctc ttcactttcc
    16621 ttaaatacta ctatatagaa actatcaaaa atcaattgat agttttttgt tgttattgaa
    16681 tggctttaaa acctcttatt aataaagaag tgattatttt gaatttatta gaagaaaaaa
    16741 acgcttatga aacttatagt tgaattaatc tatgagagaa aagcaattac cagtctttgt
    16801 gagacaatcg aaaaacgatt aaaccaaata gaaaaaattg attacgcaaa atttaatgat
    16861 caaaaaataa agactacttc tattctcacg acattatttc taaaaatatc tgctacattt
    16921 ttaaaacttc tggcataccg atgaatgctt cacaaattta ttctgtaatc acaaaaaaat
    16981 ctacatttca atttaggtta taacaatcta gtaaataata ttttaccaaa aatgccagac
    17041 gataatagct tacctgttaa aaaagttcat aaaagttttt ggcagtatag acatcaggaa
    17101 aagtcacata gatataggag gtagtttaca tggacaatac tccaagcgat aacaaactaa
    17161 aaaaatacat tcatataggt gtactacact atcatgcaaa caactattat aaaaaaagag
    17221 gaactactcc actagactac tctttaccta ttttcacgat atcacgctcg attcttctta
    17281 cacatataac tattttaata ttatcaatat gtcatcactt gacttgaaaa actttgaaac
    17341 ttattttgaa gatgaattgc ttatataagc aatcaaacaa cttaatatta aagaaaagag
    17401 atttctacta gaaaaatatg ttgtaaaaaa gaagatatta tgtaccgtgt cggccataaa
    17461 gattcaaaga tgactcgaca agtatataac tacttctacc ccgaacgtaa ggagcgtagc
    17521 gctgaccaat tcgctcagtt tattgaaaag gaaaaatatc ttttctaaaa gaaattgtag
    17581 ttagtttgct tttttgaaaa aaagaagcac cagaaacatt gataaatcaa catttctagc
    17641 gctaaaaaag gttttaccct acactgcctt ccatctcata actaatcaac cgattcaact
    17701 caaccgcata ttccatcggt aattctttcg taaatggttc aacaaagccc ataacaatca
    17761 tttctgtggc ttcggcttca gataagccgc gactcattaa ataatataat tgttcttcag
    17821 aaatttttga aactttggct tcgtgttcta aggacacttg gctgttatgg atttcgttaa
    17881 acggaatcgt atctgatttt gatttttcgt ccatgataat cgtatcgcat tcgatgtggg
    17941 aaatcgatcc tgcgctgtct ttgccaaaag taacttggcc acggtagtta acttcgccgc
    18001 cgtctttagc aattgatttt gaaacaattg agctagaggt attcggcgca ttgtgaatca
    18061 ttttggcccc agtatcttgg atttggttag cgccagcaaa ggcaatcgat aacatcgtgc
    18121 cacgggcacc tttgccatct aagtaaacgc ttgggtattt catggttgtt ttagctccta
    18181 ggttcccatc aatccattcg acagtggcac cttcgtaagc tttagcacgt ttggttacta
    18241 agttgtagac gttatctgac cagttttgaa tagtggtata acgacaatag gcatcttttc
    18301 tagtgaaaat ttctacgatg gccgcatgca agctgttact tgaatacgtg ggtgccgtac
    18361 agccttcaac atagtgaacg ctggcccctt catcgacaat aatcaaggtc cgttcaaatt
    18421 gtccggtatt ttcagcgttg attcggaaat atgtttgtaa tggtacatca actcgaacgc
    18481 cttttggtac ataaataaag gttccacctg accaaacagc tgagtttaaa gcggccagtt
    18541 tattatctgt tggcggcaca agttttgaaa aatactcttt gaataggtca ggatattctt
    18601 ttaaagcaga gtcagtatct gtaaaaatga tgcctaattt ttcaaattct tctttcatgt
    18661 tgtggtaaac aacttctgat tcatattgag cagaagcccc agctagataa gcacgctcag
    18721 cttcgggaat cccaattttt tcaaaggttt ctttgatttt atcaggtaca tcatcccaat
    18781 cgcgtgcggg tttgtcactc ggtttttggt aatatttaat tttactaaag tcaatatctg
    18841 acaggtctgg accccattct tgcatgggca ttttattgaa ttgttctaac gattttaaac
    18901 ggaagtcaag catccattct ggttcgcctt tcacgcgaga aatttcgcga acgacgtctt
    18961 ctgttaggcc gtctccggta ctaaagactg gttccacatc gtcgtgaaag ccaaatttat
    19021 attcttctaa ttcaggtact gtactcaatt cgtcgtcacc ctttctttat ttttcacaat
    19081 gtaaatgacc ggcttcgcct tggccgttat tagcaacagc ctgctctaag gctttccaag
    19141 ccagggttgc acatttaatc cgagctggaa atttagctac gccgcttaac attgctgcat
    19201 cgcctaattt ttcatcttcg gccacttcat ttccttgaac aagttgagag aaatcctctg
    19261 ctaaggccgt tgcttcggcg attgtttttc ctaagaccgc atcagtcatc atactagcac
    19321 ttgcggtact gatggaacag ccacttcctt gaaaggcgat atctttaatc acaccgtctt
    19381 caatggccac atccagttca atcacatctc cacaagtagg attattcagt tcaattgttt
    19441 ggctagacgc atctagcgtt ccgtggtgat gtgggtggct agaatggtcc aaaatgactt
    19501 ggcgatataa gttatctaat ttagaaagtg ccatgctgga aaaactcctt tgtcgcttta
    19561 atcgcttcaa ctaagcgatc tgcgtcttct ttggtattgt ataaataaaa acttgcccgt
    19621 gcggttgctg gcacgctcaa atagtttaat aacggttgcg cgcaatggtg acccgctctg
    19681 acagcgaccc cttccatatc taacgccgta gccacatcat gtggatgtaa accttcaata
    19741 ttaaaagcaa tcacacctgt gtggtctttt ggattctgtg gaccataaat cgtcaagccc
    19801 tcgatagctt gcaacttcgg caaaacatag tgaacaaggg ctgcttcatg ttgatgaatg
    19861 gcctctaaac caatttctgt taaataatca atggcggcac ctaaggcaat tgccccagca
    19921 atattaggtg tgccagcttc aaatttccat ggaagctctt tccaagtact ttcttgaaga
    19981 tgaacaaagt caatcatttc gccaccaaat tccacaggtt ccatttgttc caataaatga
    20041 cgtttgccat aaaggacacc aattccagtt ggtccacaca ttttgtgacc actaaatgca
    20101 taaaaatcag catcgatagc ttgaacgtcc acaggcatat gaggaactgc ttgcgcgccg
    20161 tctaccacca tcacagcgcc attttgatga gctaattgtg ttaattcttc gattggatta
    20221 atgaccccta acacatttga aacatgagca atcgaaacaa ttttcgtttt ttctgtaatt
    20281 tgttgacgtg cacttgccat gtctaaaaag ccgtcttcag tgacgtctat atacttcaaa
    20341 atggctcctg tacgttgggc taattgttgc cagggaataa tgtttgaatg atgttccatg
    20401 taagatatga cgatttcatc cccggctgta actgccaagt caccataact tttggcaatc
    20461 caattcaaac tggttgttgt tcctcgtgta aataaaactt ccgctgtttc tttggcatgg
    20521 ataaattggc gaaccttttc gcgggaggcc tcatagtcct tcgttgctcg ttcggctaac
    20581 gtgtgcaccc cacgatgaac attggcatta tcggtttcat aataatgtcg taaaacatct
    20641 aacaccgccg ttggtttttg ggttgtcgca gcattgtcta aataaactag cggttcatca
    20701 ttaacttctt gaaataaaat aggaaacgat tgacgaatgg ttgctgcatc catcatgcgt
    20761 ttaacttccc ttcaattact tctacaaatt cattttgtac ttctttaact ggaattgctg
    20821 taatgacaga acctaggaag ccacgaatca ccaaacgttc cgcttcttct ttacgcaagc
    20881 cgcggctcat taaataatac atttcttctg gatctactcg accaacgctg gctgcgtgtc
    20941 cggcagtcac ttcattttca tcaattaaaa gaattggatt ggcatcacca cgagctttat
    21001 cagacagcat taaaacacga ctttcttgct gtgcgtcggc tccttttgct ccttttaaaa
    21061 tgtggccaat tccgttaaac gttaaagtac cacgttcacg aataactcca tgttgtaaaa
    21121 tatgaccaat tgaatgtggc gctttgtttg tcactcgtgt gtcgatgcct tgtgtttgtt
    21181 tacctgcact aattgcaaca actttaactt ctgaatgagc gccttcgcca actaaatcag
    21241 aatcaaaatc agccacaaca tcgccatcat tcatgacgcc tagagcccaa tcaacagagg
    21301 catcccgcat aatatagcca cgacgattca tataagtcgt tacagtttgc cctaattgat
    21361 ccacggctga gtatttaact tttgcgccat ctttcgcaat cacttccaca acgatatttc
    21421 cagaagcttt ctctgcgtga tgaccagttg attgaaaacg ttctaaataa ctgaattcac
    21481 tatgattatc tgcaacgatt aaaacatgtt taaagaaagg ttggttgcta tctgaatcct
    21541 gaataaacaa agattcaatg ggctcttcaa tcactacgtt tttaggaacg tataagaaaa
    21601 cgccactatt catgaaagct gcatgagctg ctgtcagctt atcttcttct ggtaatacag
    21661 ctttagtcat atagtattct ttaactaatt ctgggtgctc ttgtaaagca gtaaaaatgt
    21721 ctgtaaaaat taccccttgt tccgctaatg aggctggcaa ttgctcaaaa gcatgaaaag
    21781 atccttgttg aacaattaaa ggattgtctt tcatttgatc aaaacttgcg acatttcctt
    21841 cagaaggcac ataactttcc atgtgaacat ttaataaagg ccaacgatga aatttcacac
    21901 gatcaatatg tggtaactca ctttcgtcag cgtttcttaa agccgttgtt cgcaattcag
    21961 tcatccaagc tggttcttca tgttctagtg aaaaagcggt gacttcgtca agataatcca
    22021 ttagatttac ttttttcatt tatcttgtcc tccttacgct tcttctttgt aatcaatacc
    22081 taattcttgg ctgataccag catagccttc tgtttctaaa cgttttgcca aatcagcccc
    22141 accggttttc acaacgcggc cttccatcat gatatgaaca acatctggcg tgatatagtt
    22201 caataagcgt tgataatggg taataattaa cgcaccaaag ttctcgccgc gcatttcatt
    22261 aaccccttta gaaactactt ttaacgcatc gatatctaag cctgaatcaa tttcatctaa
    22321 aatggcaaac gttggctcta acatcaataa ttgtaaaatt tcatttcgtt ttttctcgcc
    22381 gccagaaaaa ccttcgttta agtaacgctc agccatttct tcaggcatat ttaataattc
    22441 cattttgcta tctaattttt ttaagaactg cataactgac attttgttgt cttcgtcacg
    22501 ttttgcattg attgctgcac gcatgaattc agcattggta atccctggaa tttcacttgg
    22561 gtattgcatt gctaagaata agcctaagcg agcgcgttcg tctacttcta aatctaaaac
    22621 gttgacgccg tcaaacagaa tttctccttc tgtgacttcg tagttaggat ttcccataat
    22681 tgctgctgat aaagtagatt taccagttcc attaggtccc ataattgcat ggatttctcc
    22741 agtattaatt gttaaatcga ccccttttag aatcttttta tcttcaattg atacgtgtaa
    22801 atttttgatt tctaacacag acatgtacaa ttccctccaa cttgttttaa tcgtttttcc
    22861 gttctcactc attttagcct aattgagaat gaatcgcaaa ttacaattgc taaaaataac
    22921 aactcttatc atcaaatttt aggattcaat ttgtgaagga aaattttaaa aggctgatat
    22981 ttcaaagttt ctctatattt ttaagtgatc gtccctacac aaagaaaaat attctggtag
    23041 aataaaaaaa tttattcaag aaagcgtttt cttaaataat tactttagaa tgactttcgc
    23101 aaagagagcc ttgagatacg ccttcctcat ctatacaaaa aaatccagag catttgcttc
    23161 tctggattca ataattttta ttagtgattg gttttatact tctaaaagtt cttgttcttt
    23221 ttcagcagta atcgcatcga tatttttgat gctatcatct gttaattttt gaacatcttt
    23281 ttcaaatgaa cgtaattcat cttcggtgat gtcgccattt ttttgagctt ttttcaactc
    23341 atccattgca tcacgacgaa cgttacggac agcaactttt gagttttccg cttctttttt
    23401 cacgtctttg gctaattctt tccgacgttc ttccgttaat tgtggaatca ctaaacggat
    23461 gacatttcca tcattggttg ggctaatgcc gatatcactc atttgaatag ctttttcaat
    23521 gtcagcgata gaatttttgt caaacggtgt aatcattaat acacgtgctt ctgggatatt
    23581 gatacttgct aattggttaa ctggtgttgg tgcaccataa tattctactt gaatacggtc
    23641 taatagactt gcgttcgcac gaccagcacg aatttgacct aattcacggc gtaagctttc
    23701 ttccgctttt gtcatttttt ctttggctgt tgctaaaact tctttagaca ttctttattt
    23761 cccccttaca gttgttccga tattttcacc aaggatggca cgacggatat ttcctgcttc
    23821 atttaggtta aagacaacta aaggaatatc gttatccata cttaatgagc ttgctgttga
    23881 atccattact tgtagccctt tagaaataac atctaaatgt gttagttctt caaattttgt
    23941 cgctgtttca tccacacgtg gatccgcaga ataaacacca tcaacattgt tcttcgccat
    24001 taagatgacg tccgcatcta cttctgcagc tcgtaacgca gccgttgtat ctgtcgagaa
    24061 gtaaggattt cctgttcctc cggcaaaaat aacaacgcgg cctttttcta aatgacgttc
    24121 tgcacgacga cgaatgtatg gttctgcaat ttgacgcatt tcaattgatg tttgaacacg
    24181 tgtaggcaca ccaagatttt ctaatgtatc ttgcaatgct aaggcattca tcacagtagc
    24241 taacatgccc atataatcag cttgtgcacg ttccatgccc atttgagcac caatttgtcc
    24301 acgccaaatg tttccgccgc caaccacg
//
