LOCUS       NZ_KB944648            25975 bp    DNA     linear   CON 12-JAN-2024
DEFINITION  Enterococcus faecalis EnGen0364 strain T6 acAqR-supercont1.1, whole
            genome shotgun sequence.
ACCESSION   NZ_KB944648
VERSION     NZ_KB944648.1
KEYWORDS    WGS; RefSeq.
SOURCE      Enterococcus faecalis EnGen0364
  ORGANISM  Enterococcus faecalis EnGen0364
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 276587)
  AUTHORS   Earl,A.M., Gilmore,M.S., Lebreton,F., Walker,B., Young,S.K.,
            Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B., Abouelleil,A.,
            Alvarado,L., Arachchi,H.M., Berlin,A.M., Chapman,S.B., Dewar,J.,
            Goldberg,J., Griggs,A., Gujja,S., Hansen,M., Howarth,C.,
            Imamovic,A., Larimer,J., McCowan,C., Murphy,C., Neiman,D.,
            Pearson,M., Priest,M., Roberts,A., Saif,S., Shea,T., Sisk,P.,
            Sykes,S., Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     The Genome Sequence of Enterococcus faecalis T6
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 276587)
  AUTHORS   Earl,A.M., Gilmore,M.S., Lebreton,F., Walker,B., Young,S.K.,
            Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B., Abouelleil,A.,
            Alvarado,L., Arachchi,H.M., Berlin,A.M., Chapman,S.B., Dewar,J.,
            Goldberg,J., Griggs,A., Gujja,S., Hansen,M., Howarth,C.,
            Imamovic,A., Larimer,J., McCowan,C., Murphy,C., Neiman,D.,
            Pearson,M., Priest,M., Roberts,A., Saif,S., Shea,T., Sisk,P.,
            Sykes,S., Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2013) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: allpaths v. R42411
            Assembly Name                     :: Ente_faec_T6_V1
            Genome Coverage                   :: 145.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/12/2024 01:33:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,852
            CDSs (total)                      :: 2,769
            Genes (coding)                    :: 2,732
            CDSs (with protein)               :: 2,732
            Genes (RNA)                       :: 83
            rRNAs                             :: 7, 4, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 4, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 3 (23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 15 of 37
            Pseudo Genes (incomplete)         :: 18 of 37
            Pseudo Genes (internal stop)      :: 13 of 37
            Pseudo Genes (multiple problems)  :: 8 of 37
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:06:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 79635
            Orig. end                         :: 105610
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB944648.1.
            Please be aware that the annotation is done automatically with
            little or no manual curation.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25975
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25975
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25975
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15975](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15975
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    66..79
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 22.87"
                     /tool="antismash"
     gene            399..926
                     /locus_tag="WMM_RS03710"
                     /old_locus_tag="WMM_00069"
     CDS             399..926
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363538.1"
                     /locus_tag="WMM_RS03710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00069"
                     /product="DUF308 domain-containing protein"
                     /protein_id="WP_002356034.1"
                     /transl_table=11
                     /translation="MEQRQHHGMDWGSLVLGILFVLTALISFQNPAGNLIAIVMVFAIF
                     AIIKGIFEIFVRNRMKELLGYKAYAPIILGIIDILIGVYLLFNLNIGVAVLPFVFAIWF
                     LFDSIFGLFTLDFAKRVSTGYFWFTLIVDVLGIILGVMLLFNPLSSALTLSFLVGFYFM
                     MFGISNIVYAFR"
     gene            complement(975..1178)
                     /locus_tag="WMM_RS03715"
                     /old_locus_tag="WMM_00070"
     CDS             complement(975..1178)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002381332.1"
                     /locus_tag="WMM_RS03715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00070"
                     /product="hypothetical protein"
                     /protein_id="WP_002381332.1"
                     /transl_table=11
                     /translation="MNNQRPMFINILLVVLLFLVVGSLFSAVVGIVGSLLWLAVKILVP
                     VAIIVWLVRTISGNNGNCRRRY"
     gene            1376..2146
                     /locus_tag="WMM_RS03720"
                     /old_locus_tag="WMM_00071"
     CDS             1376..2146
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414993.1"
                     /locus_tag="WMM_RS03720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00071"
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="WP_002387434.1"
                     /transl_table=11
                     /translation="MSTEGLIALLEKKRNHLSKIENQVLDYILTHMTEISSQTIYEVAQ
                     ALFVSTATISRTAKHLGYRGFQELKYAIVQSVQSESTESDSRSFQAITQQLIANVQDSF
                     QQMDEAKVAEMLKMIERANTIEVFGVGGSFPICTDFARKLTFLGKKAYARSDWDEQAAA
                     VKNLDGQDLAIFVSYTGETKGILAYARVAQEQQVPMISLISTKGSTLEKLSTTTLFAKG
                     TTRYHQRVDLSSRIAVICLFDTVLLMYAEAKQPR"
     gene            2295..3863
                     /gene="malX"
                     /locus_tag="WMM_RS03725"
                     /old_locus_tag="WMM_00072"
     CDS             2295..3863
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005355 - glucose transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0005363 - maltose transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene="malX"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627297.1"
                     /locus_tag="WMM_RS03725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00072"
                     /product="maltose/glucose-specific PTS transporter subunit
                     IIBC"
                     /protein_id="WP_010818093.1"
                     /transl_table=11
                     /translation="MAVKKKKATFWEFFQGLGKTFMLPVALLAFMGILLGLGSSFSSES
                     MIETIPFLGKPAVKIIFQFMSTIGGFAFAYLPVMFAMAIPLGLVRKEKGIAAFSGFVGY
                     TVMNLAINFYLVQTNRLVDPEQLREAGQGMVFGIQTIEMGVLGGIIAGLIVYKLHNRFY
                     TVQLPDSFAFFSGARFVPIITSLVMAFVGLVIPLVWPLFALMIMAIGQLIQRSGIFGPF
                     LFGSGERLLLPFGLHHILVSMIRFTEAGGSAVVAGKEVFGALNIFYAELQNNLPISPSA
                     TAFLSQGKMPTFIFGLPAAALAMYHTAAPANRHKIKGLLLSGVIATAITGITEPIEFLF
                     LFISPLLWLFHVIMTGLGFMVMALLGVVIGNTDGGLLDFVIFGLLQGTYTKWWWVLIVG
                     AIWFVIYYFVFKTVIVTFDLKTPGRDKVLDETEYTDQEVQYKKTGGYDAPGILAALGGQ
                     ENIQAIDNCITRLRLVLADANKVDDDKLKQLGALGVVHLDAQNVQVIIGTKVTTVRNQL
                     EMILG"
     gene            3878..5092
                     /locus_tag="WMM_RS03730"
                     /old_locus_tag="WMM_00073"
     CDS             3878..5092
                     /EC_number="4.4.1.13"
                     /GO_function="GO:0004121 - cystathionine beta-lyase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (34-383). E-value:
                     1.2e-43. Score: 141.5. Matches aSDomain:
                     nrpspksdomains_WMM_RS03730_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635155.1"
                     /locus_tag="WMM_RS03730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00073"
                     /product="MalY/PatB family protein"
                     /protein_id="WP_025189680.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.1e-43, bitscore:
                     141.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSVSFDKAIDRRGTYCTQWDFVEDRFGEADLLPFTISDTDFAVP
                     EAVLATLQERLKHPVFGYTRWNHPQLKEAIQTWYQTRFQTKIEEHWIMYTPTVIYGISA
                     LIQLLTNEGEGIILQTPAYDAFFKVIQENKRQVVANELLYQAKRYSIDFIDLEKKLAQP
                     ENRCLLLCSPHNPTGRVWEQWELERMVSLCQQYDVFLLSDEIHMDIVNKGHVHRPITQF
                     NYKKSAIITSGTKTFNFPGLIFAYALIPDNELRDAFQLKLKNADGLSSTSILGMLATMT
                     AYQKCGTWVDELNDYLAENQRYVKDFLQTYLPKIKVTELEATYLMWLDVSAAVPDVARL
                     QEALVSVGKVAIMDGSIYGGNGQRFLRLNIGCSQAKLHEGLERMRQGFEAVLQKDGTAS
                     ALGNN"
     aSDomain        3980..5026
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_WMM_RS03730_Aminotran_1_2.1"
                     /evalue="1.20E-43"
                     /label="WMM_RS03730_Aminotran_1_2.1"
                     /locus_tag="WMM_RS03730"
                     /protein_end="383"
                     /protein_start="34"
                     /score="141.5"
                     /tool="antismash"
                     /translation="FTISDTDFAVPEAVLATLQERLKHPVFGYTRWNHPQLKEAIQTWY
                     QTRFQTKIEEHWIMYTPTVIYGISALIQLLTNEGEGIILQTPAYDAFFKVIQENKRQVV
                     ANELLYQAKRYSIDFIDLEKKLAQPENRCLLLCSPHNPTGRVWEQWELERMVSLCQQYD
                     VFLLSDEIHMDIVNKGHVHRPITQFNYKKSAIITSGTKTFNFPGLIFAYALIPDNELRD
                     AFQLKLKNADGLSSTSILGMLATMTAYQKCGTWVDELNDYLAENQRYVKDFLQTYLPKI
                     KVTELEATYLMWLDVSAAVPDVARLQEALVSVGKVAIMDGSIYGGNGQRFLRLNIGCSQ
                     AKLHEGLER"
     gene            5192..5572
                     /locus_tag="WMM_RS03735"
                     /old_locus_tag="WMM_00074"
     CDS             5192..5572
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356039.1"
                     /locus_tag="WMM_RS03735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00074"
                     /product="RidA family protein"
                     /protein_id="WP_002356039.1"
                     /transl_table=11
                     /translation="MKTIKTKQAPQAIGPYSQAKIVNGLLITSGQIPLDPETGKVVGTT
                     IKEQTNQVLKNIQGILTEAGSDFAHVVKTTCYLQNMADFTAFNEVYAEYFSAEYPARTT
                     IEISKLPMDVLVEIEIIAEVVA"
     misc_feature    5627..5640
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.11"
                     /tool="antismash"
     gene            5764..8355
                     /gene="mprF"
                     /locus_tag="WMM_RS03740"
                     /old_locus_tag="WMM_00075"
     CDS             5764..8355
                     /NRPS_PKS="Domain: LPG_synthase_C (532-828). E-value:
                     1.2e-49. Score: 160.9. Matches aSDomain:
                     nrpspksdomains_WMM_RS03740_LPG_synthase_C.1"
                     /codon_start=1
                     /gene="mprF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LPG_synthase_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396739.1"
                     /locus_tag="WMM_RS03740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00075"
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="WP_002378676.1"
                     /sec_met_domain="LPG_synthase_C (E-value: 4.9e-49,
                     bitscore: 160.9, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKNISQLTQWLKEHSLLLKLIFLGSVLVFVANQVTHIAQGMTWA
                     DIFSTMEQQSTGRLIGMVLAGLLGVIPMLLYDYVVVKLLEKEGKPPMKRMDWLTSAWVT
                     NTINNLAGFGGVVGATLRINFYGKDVPRGKVVATVSKVALFLISGLSILSFVAFVDLFF
                     IRTQNVFREYWVWLLLGSLIAPALWFFTYLKRRTLFKTFFPKAVLLLFGASLGQWLGGM
                     FAFLMIGRLMQVPVSMVSVYPMFVIATLIGMLTMVPGGMGTFDVLMILGLSQLGIDRSQ
                     AVVWLLYYRLFYYVTPFMTGVILFLQQAGMKVNQFFDNLPRLFSQKVAHFILVAALYFA
                     GIMMVLLSTVTNLSNVSRLFQVLLPFSFNFLDQTLNLFVGFLLLGLARGISMKVKKAYW
                     PTIILLGFCIVNTVARTTSWQLIAVYAVILLAVILARKEFYREKFVYSWGALTVDSILF
                     GCLFIGYAVAGYYAARPAGGNQVINHFLLFPSDDVWFNGLIGLSISLIGLFFLYQYLAE
                     TTVTLGEGFEEARLTRFLEKFGGNEGSQFLYLKDYGHFYYQEEGEDQVLFGFQMKFNKC
                     FVLADPIGQREKWTAATLAFMDQADLLGYQLVFYRISEEYVMNLHDCGFEFMKVGEEGL
                     IQFDEPSTVNQTAWTETVTEKIAAEAADFQFEFYPETISDALYQELERVSADWSRNQKE
                     RYFIGGRLDPEYLKCSSVGLVRQKQTVIGFITGKEMEKGKSISYDLLRIRSEAPAFTRE
                     YLFTHFIETYQQQGYQLIDIGMAPLANVGESKYSFLKERFVNIFYKYSYQIYAFQDTRK
                     RKEQYVTSWQPRYFAYPKRTSVLFAFVQLSLLITKGRHQSVSLVEEAMTEI"
     aSDomain        7360..8247
                     /aSDomain="LPG_synthase_C"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_WMM_RS03740_LPG_synthase_C.1"
                     /evalue="1.20E-49"
                     /label="WMM_RS03740_LPG_synthase_C.1"
                     /locus_tag="WMM_RS03740"
                     /protein_end="828"
                     /protein_start="532"
                     /score="160.9"
                     /tool="antismash"
                     /translation="RFLEKFGGNEGSQFLYLKDYGHFYYQEEGEDQVLFGFQMKFNKCF
                     VLADPIGQREKWTAATLAFMDQADLLGYQLVFYRISEEYVMNLHDCGFEFMKVGEEGLI
                     QFDEPSTVNQTAWTETVTEKIAAEAADFQFEFYPETISDALYQELERVSADWSRNQKER
                     YFIGGRLDPEYLKCSSVGLVRQKQTVIGFITGKEMEKGKSISYDLLRIRSEAPAFTREY
                     LFTHFIETYQQQGYQLIDIGMAPLANVGESKYSFLKERFVNIFYKYSYQIYAFQDTRKR
                     KEQYVTSWQPRYFAY"
     gene            complement(8420..9125)
                     /locus_tag="WMM_RS17650"
                     /pseudo=""
     CDS             complement(8420..9125)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611387.1"
                     /locus_tag="WMM_RS17650"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGNRVSYPIHIKEMAIQMKKENIPVKIIMAELGIKNKTQIETWWR
                     WYRNGENHRLVQPVGKQYAYGKGPEILSNEQQLRNENNYLKMHIEVLKKYKELERTWSQ
                     K"
     misc_feature    complement(9460..9474)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 16.29"
                     /tool="antismash"
     gene            9509..9652
                     /locus_tag="WMM_RS18280"
                     /old_locus_tag="WMM_00078"
     CDS             9509..9652
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="WMM_RS18280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="WMM_00078"
                     /product="hypothetical protein"
                     /protein_id="WP_010818097.1"
                     /transl_table=11
                     /translation="MKIRREYDTHAIEITRWNKGNLVYTIDCDCGRQADRVIGMYETFI
                     KK"
     gene            10001..11224
                     /locus_tag="WMM_RS03760"
                     /old_locus_tag="WMM_00079"
     CDS             10001..11224
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="WMM_RS03760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00079"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_010818098.1"
                     /sec_met_domain="LANC_like (E-value: 1.2e-17, bitscore:
                     57.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYEKIINQCELVIKNQTTRNINSYHGLRDYTFFLSSLIKVTPNL
                     YELIEEKIIRNTNSIDEYVEGIITSPGLWHGLSSYGYLCAELNDNKNLQYSYEKKNQKL
                     SNMVELLSKNIGEIKIKSLQQIRNHKWFDIFYGVTGIIVYLFRVERFESAKKLIYMLTD
                     SILLTEFLDVYNSPFSEKIEAYFPGKFDRNSGNIINLDVSHGILSVFFVIKEAHIIFPN
                     DQRIFDAYTCIRNFYVSIFNVKNSSYHKQITDYSDIRISKFKSNWARGDLPLIIQLLSV
                     KDPLFDISDNRDYLKKNINDRLLKEQDDMNFNFCNGIAGVNFQLKIINQYFYLNYFEKC
                     VDEKIINGLDQKIDKEIDEKEDQRLVFKTINDMNIIDGSFSIIVPKILSNHYSDLTQTF
                     IAKMFCIK"
     gene            11237..13009
                     /locus_tag="WMM_RS17565"
                     /old_locus_tag="WMM_00080"
     CDS             11237..13009
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="WMM_RS17565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00080"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_010818099.1"
                     /transl_table=11
                     /translation="MKKTYFIVKRIIELSITLDKKHLISFFLVNIIKLIFPLLIMINTQ
                     TIVNNIQTGIPFHSPEFFSLIILFPILNVFSELFNNLNTYLSSRYSDILNFKFSELQLK
                     SVFKHSLEDFENPEFYDLIQRAEQAGGVYPFQIIMTMVSVSSILLTSISYIIILLRWKW
                     WTIILLFLFPFISSIKTLRLSKDEFTIMYSRTNLERKSWYYANLLNKDEFFKETTLYSL
                     GNNFLEEFTNLRKKFINENKKMYRRRNKFTFLVSFITIFTTSIILCIVFYEASVGIILI
                     GSLMTYVNSISTLKNNFSSIINSFFSLHQQSLYAKNILDLLDYKSIPEEKPNHQKKITI
                     KQINSIELKNVSFKYVQSSRYALKDISLNFEKGKKYIIVGKNGSGKSTLLKIILGFYNN
                     FEGEMLINEIPFSDIDINSYRKCISAVFQDFAKYQFKINETISLSKNRDIDMRDIKKAA
                     SEANASQFIKQLPFKYEQQLGSWFPNGIQLSGGEWQKVSIARAFYKDNASLVVLDEPSS
                     ALDPISEEKVFKSYKSLVNNKIGIFVTHRIKNIDFEGDIIVLNLGKISEYGKQSDLIKK
                     QGLFYELSTAKKQF"
     gene            13024..15975
                     /locus_tag="WMM_RS03770"
                     /old_locus_tag="WMM_00081"
     CDS             13024..15975
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="WMM_RS03770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00081"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_010818100.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.5e-54, bitscore:
                     177.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.2e-12,
                     bitscore: 41.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.8e-25, bitscore:
                     82.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYIVCDDFIYRRAEFSIDSFFDFLNNVSNEEILKKANNEYREVL
                     YSLSSNLLKSLANVNMDKEKLCIALYKYISRCSSRATPYALSATVGLGEFSEQQNFNIS
                     KRFKHDNILVDVDGRWAFDVMRIMEEKLFDDLKIKVNNTLRFHEKDIVNIWVTNEDNSN
                     IYKNNLVINRTKALDIIISAAKDETTIHKLLEKLSNEYPNVNNTVFINFLHELINSEIL
                     ISDIRISLLEPNIINNLAKVLKKYHVFEESKKIIEINEICQNFNCNTERNFIEKADMLI
                     GKMKDICISKKYLNIINKSHDCLHIPHKSKKEISDFITFITKISELLPKPLNNYKNQFV
                     DRYGFNLAVPILDVFYDKKLLFDDDERLVRENQLYKSLMRKISNGNINSIIDISYLVSK
                     YDYKPKRYHSGIEMSFYLLNNNDCFEYIISPLVGSDAIGRSFGRFDFYFDNKMSKRRNQ
                     ILSTSPQYETVDLTFFPKEKTLLNVMNGPKSSEMQFKFGSNDFEENLNIQFDDIYIYLD
                     SDGDFHFFDINSEKEIIFNVNNMVNLNYAPEIVRYIMALRSKSEPQVFDIFHVLNAIGT
                     DLGFLPKITYKNFTITPKKKYIFKDLDNFYKVGLEKGLEKRIIQELLNCFPSGRFFLEN
                     GDNRIIVDIKTDIGQKIAIKELVNNQCLLASDIPFKAECLPINDGNNSYVGEFVFQIYS
                     SNEQKVRQNNFEIMNTRPSEYSYLPFDKYLYYKIYCSRQNQNRLLQIEISPWVSKLKEE
                     GLIKGFFYVKYKDEKDHLRLRFILNESTNIEKLTSINLNFLKQYEKKELIDDVTMNIYE
                     REVYRYGGKDQLDELENIFSIESEVFLKSINCLSYTEKNFLFFNIVLYYLGISGVSSEE
                     IVDMLKVYKMKKEHRKEFLIFFDENNNEKISHNIEQILKEFKYYEEEIAIALNRVRMHN
                     SSEKRNEIYLSIFHMLHNRLIGIDRENENKIMSFTNREYRIAYEKKKGGQNNG"
     aSDomain        13507..13707
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_WMM_RS03770_Lanthipeptide_LanB_RRE.1"
                     /evalue="3.60E-13"
                     /identifier="RREFam001.1"
                     /label="WMM_RS03770"
                     /locus_tag="WMM_RS03770"
                     /protein_end="228"
                     /protein_start="161"
                     /score="41.0"
                     /tool="antismash"
                     /translation="SNIYKNNLVINRTKALDIIISAAKDETTIHKLLEKLSNEYPNVNN
                     TVFINFLHELINSEILISDIRI"
     gene            15968..17269
                     /locus_tag="WMM_RS03775"
                     /old_locus_tag="WMM_00082"
     CDS             15968..17269
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016027.4"
                     /locus_tag="WMM_RS03775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00082"
                     /product="glycosyltransferase"
                     /protein_id="WP_010818101.1"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 1.7e-08,
                     bitscore: 28.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKIAVIFGGGFISHINPLKPLIKHLNEENYKVYLFNIEKYKEIV
                     EGLGCFFIKYPNKIDETKYQEIEIKYLKELEQEQLKGNVIEYYKLITKIGAIRSHTFNH
                     RIFYKLFSDVKKLNPTIIFCDAINMYGDLIAKELGIECIGYITNNIYNYSFLNTDNGYL
                     WKTFSRHWGTSYFFDKDFFSKYWEYLCKTYKEVSVENNLEYLEPMRHFEPRSKKIIIFS
                     SKYIQPKRALCNEKSYFFIPSIVNNFEITDTELKKFCKGMNKIVYIAHGSYLDVNLNHY
                     LPLIKILTERGIKIVISTGKYHASFIEKLPKKVKLSNLIFCAPIINQKDALFMCDLFIT
                     HGGMNSIMEAISFETPMLLNPITPEQRMNALIVNNKKIGISNYKLPRELTTGQAILKLL
                     EREKYVNNLHKLKLKILKEVENLDKEKLNEFLRK"
     gene            17276..17986
                     /locus_tag="WMM_RS03780"
                     /old_locus_tag="WMM_00083"
     CDS             17276..17986
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015325.4"
                     /locus_tag="WMM_RS03780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00083"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_010818102.1"
                     /transl_table=11
                     /translation="MNKIFSYCGSAQDISVTNNVSKELLYQLSSKLNSQVLIKHFRCKD
                     VNINFVDNLNQFINPNIAMSTNDDMEMLSKELLASKIVIFSTPVYFKSVSAGMKIFLDR
                     LVGWTHTFELTGRYGVIIVCGSQNGSEETVKFLEDFMIRLGLGTIQVIEYNSNEDSEES
                     LRKRIEMISDNLSIRIKENLAPEPTEIQKKIYSDYRRVFLSENINPIEHEIWLEKTKEN
                     HNLAELFKLNYHKL"
     misc_feature    18012..18026
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 18.71"
                     /tool="antismash"
     gene            18085..18270
                     /locus_tag="WMM_RS03785"
                     /old_locus_tag="WMM_00084"
     CDS             18085..18270
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="WMM_RS03785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="WMM_00084"
                     /product="hypothetical protein"
                     /protein_id="WP_010818103.1"
                     /sec_met_domain="TIGR03731 (E-value: 9.7e-08, bitscore:
                     25.9, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDLKDFDLNITQETQENSSVDIQPRSTSVVSTVIWSIIGTSAAT
                     TQFGGDPTWTENSKCR"
     gene            complement(18447..19202)
                     /locus_tag="WMM_RS03790"
                     /old_locus_tag="WMM_00085"
     CDS             complement(18447..19202)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608585.1"
                     /locus_tag="WMM_RS03790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00085"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_010818104.1"
                     /transl_table=11
                     /translation="MLIQNILKTYRINNHYTQEQIAEKVHVTTQAISKWENGLSIPSID
                     NLLILSDLYNVSIDELVQGSPYFKKPRIIGKKFNLKKGILFLLVWTLISLLFTGFGYQP
                     IWIFILMMLVGIILVFPTVFPNYWIIEQNYIEIHQYSKNVLNKLVELVKGIKHPKKIAY
                     SELSSVEIIYTKKTRLSPFDINPDYFYLMVNYNEKSIKLDFDSSVKDFLPQFVSFLSRK
                     NIPVIDNSNVTDLIISGTSLYEHFNETAN"
     gene            complement(<19489..20061)
                     /locus_tag="WMM_RS18555"
                     /pseudo=""
     CDS             complement(<19489..20061)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611387.1"
                     /locus_tag="WMM_RS18555"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="DDE-type integrase/transposase/recombinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGNRVPYPIHIKEMAIQMKKENIPVK"
     gene            complement(20171..22786)
                     /locus_tag="WMM_RS03800"
                     /old_locus_tag="WMM_00087"
     CDS             complement(20171..22786)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419443.1"
                     /locus_tag="WMM_RS03800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00087"
                     /product="YfhO family protein"
                     /protein_id="WP_010818105.1"
                     /transl_table=11
                     /translation="MKNKSRQFLKNNWPYMLASFFIPFLIMAIIYLSIGIYPGSSRSVL
                     ASDAFSQFSNFHASFNNVLHGKQSLFYTWNASLGLNYLSLISYYLGGLFTPLVFFFNNQ
                     NMPDALYFLTLLKIGSAGLSFWFLAKQTFKIPKWSHVTLSVSYALMSFIVAHSELIMWL
                     DAFIYLPLVILGIHRLMDQRKPTLLFVSYFLLFITNYYFGFMIGLFSFLYYFARTFTDW
                     QRYKSRIVAYFTTSLLAGGASMIMVLPAVLDLRTNGETLSEITTFKTEATAFLDIIMKN
                     MIGVYDTTKYGSIPFIYIGLLPLIFCLFYFVTKEIPLKNKLLFGSLFVLLIASFYITPL
                     NLFWHGMHAPNMFLFRYSFLFSFLVILLAGYGWEKFEKDDLGVLSGLILILLAIFALAM
                     GTKGATSYTYVTLTSFVLTATFLLLYFFGIAFYQLKKAPMQYLVILLLLLVSGEAIINT
                     RAMVTGILDDWNYASRSLYSEPYPDLKNLVYQTKKENDTFYRLENLNGVSANDGINYGY
                     SGISMFSSVRNRHSSTYLNALGFRSRGTNLNIRYQNNTLLMDALMGIKYNIAENNPMKF
                     GFERQAAAGKYQLYRNENALPLGFLADKEIYNVRQPLNDNLGSQTNLLNALANTNERYF
                     TFYQPTMTLQNNVTITQNTAGVTFTEKQHNVAKEISYTVNVPANTQAYLSLFPTDFAQL
                     ESSTATVTVNGSSQQSQIGITGQYYNLGYYPKDTTVNFKVSFYGTKAVSFVQPQVVGLN
                     TNAFEKAISAVQEKGVDLTTGKRSASGTFTADKDQVLVTTIPYDKGWRVKIDGKKVTPK
                     AFKDAFLSVPVSAGTHTIQFSYLPEGLIPGIVLFVLCTGGFVAYVTLIPARRNRKKEDK
                     "
     misc_feature    23147..23158
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.34"
                     /tool="antismash"
     misc_feature    complement(23303..23316)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.7"
                     /tool="antismash"
     misc_feature    complement(23304..23317)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     gene            complement(23330..23839)
                     /locus_tag="WMM_RS03810"
                     /old_locus_tag="WMM_00088"
     CDS             complement(23330..23839)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010824896.1"
                     /locus_tag="WMM_RS03810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00088"
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="WP_010818106.1"
                     /transl_table=11
                     /translation="MRTYESKKALIEAIQIASQKYLAEFAEIPETLKDHRIETVAKTPS
                     ENLAYQLGWLNLLLSWEEQEQRGLTVQTPAEGYKWNQLGALYQSFYQTYGQMSLESQLI
                     ALQDILEKLLHWIDSLSEDELFLPQQRAWATTKAQWPLWKWIHINSVAPFTSFRTQIRK
                     WKKVCL"
     gene            complement(23847..24314)
                     /locus_tag="WMM_RS03815"
                     /old_locus_tag="WMM_00089"
     CDS             complement(23847..24314)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395258.1"
                     /locus_tag="WMM_RS03815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00089"
                     /product="VOC family protein"
                     /protein_id="WP_010818107.1"
                     /transl_table=11
                     /translation="MKNTQFALFMVLNGRATEALTFYQEAFAGDILFKITNQEFKERLN
                     PSLTIPAGEEHWLSHSILQMDTFQLQLADNPLFAGMNTTPTEQLTLSLTVNSRHSAKTI
                     FEKLTRPPESCIIQEPIENEFATFYAIVKDPFGLVTQITQEKQADPTKKGS"
     gene            24379..25326
                     /locus_tag="WMM_RS03820"
                     /old_locus_tag="WMM_00090"
     CDS             24379..25326
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633033.1"
                     /locus_tag="WMM_RS03820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="WMM_00090"
                     /product="YafY family protein"
                     /protein_id="WP_002385468.1"
                     /transl_table=11
                     /translation="MEGKMKKSERLNQELFFLRTHPQFNLNQLMKTFGISKSTALRDIE
                     ALENLGVPLYVENGRYGGYRVLNKPLLPPIYFNENEVLAIFFSLQLLKLVAESPFGHSY
                     QQIQQKLLHSLDEPTQFKISQMSKVVYYEGIEQVEAPGNLEQLFHCILAQQVIQFNYTR
                     YEATTKKILPTRLTILEGYWYCSGYDVTKKAWRTYRCDFMEAIQQLNQTLDFTTEELKE
                     SYRHQQTTARTIPFKAIITEKGKEFFYKHRFDNIQLEETPTQCFLVGQIHPTETQFLAN
                     YFMGFGEEVTILEPVQVKQAYVESIMRIQKKYQE"
     misc_feature    25681..25695
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 17.37"
                     /tool="antismash"
ORIGIN
        1 aaatgggacg tatacgtttg cttcaaaaga gccgaagcga gtgttacgag ctattcgtga
       61 atatgttgat ccagatcaca tggtccaatc tttgagtttc tttgatgtca taaaaagagg
      121 gatcctctcg attgggaaaa agaaaaaata atttataact gttacttttt tataaactag
      181 atgaaaaagt agcggttttt ttgtgggaaa acgagggact tatttataca aaaaaggcac
      241 aattttgcac caaaaaagag acaatcaagt gatacgttgt ttttaatgga gttatcattg
      301 aaatggtttt cagaaagcac gatgaaaata tttgacacct tgtaaaatag tagtaacata
      361 ataagtgtaa taaattattt tatagaggag tgagtgtcat ggaacaacga caacatcatg
      421 gaatggactg gggttcatta gtattaggaa ttctatttgt tctgactgca ttaatttctt
      481 tccaaaatcc tgccggtaat ttaattgcca ttgtgatggt ttttgcgatt tttgctatta
      541 ttaaagggat tttcgaaatt tttgtacgta atcgtatgaa agaattgcta ggctacaaag
      601 cttatgcacc aatcatctta gggattattg atatcctaat tggtgtttac ttattgttta
      661 acttaaatat tggtgtcgct gtgttaccat ttgtttttgc aatttggttt ttattcgact
      721 caattttcgg cttatttact ttagattttg ctaaacgagt aagcacaggt tacttctggt
      781 tcacattaat tgttgacgtt ttagggatta tcttaggtgt aatgttatta tttaatccat
      841 tgtcttcagc attaactcta agcttcttag ttggcttcta ctttatgatg tttggtatta
      901 gcaatattgt atatgctttt agataaaaga agtaaaaaaa acaggttttc cgaaaaggaa
      961 aacctgtttt ttttttaata acgacggcgg cagttgccat tatttcccga aattgttcga
     1021 acaagccaca cgataatcgc tacgggaact aaaattttta ctgctagcca caataagctt
     1081 cccacgatac cgacaacggc actaaagagt gaaccgacaa ctaaaaataa aaggaccact
     1141 aaaagaatat ttataaacat tggtcgttga ttattcatac gtactacctc caaatttttc
     1201 ctgttttcta tatacagagt atagcaagaa cacgaaacaa gtacctccat cggaaggctg
     1261 atttttttct ctggcgaatg atggagccgc tgttggttat tttggacttt cttattgaaa
     1321 taatcagaat attctggtgt ataattataa aaaaggattt aaagtgaggg attggatgtc
     1381 gactgaggga ttaatcgctt tgttagaaaa gaaacgaaat catttaagta aaattgaaaa
     1441 tcaagtactg gattatattt tgacgcatat gacggaaatt agttcacaaa ccatttatga
     1501 ggtggcgcag gcgttgtttg tctcaacagc cactatttct cgaacagcaa aacacttagg
     1561 ttatcgaggc ttccaagaat taaaatacgc aatcgtccaa tcggtgcaga gcgagagcac
     1621 agaaagcgat agtcgtagtt ttcaagctat tacgcaacag ttgattgcca atgtgcaaga
     1681 tagttttcaa caaatggatg aagccaaagt cgcggaaatg cttaaaatga ttgagcgtgc
     1741 gaatacgatt gaagtgttcg gtgttggtgg cagttttcct atttgtactg attttgcacg
     1801 aaagctaaca tttttaggaa aaaaagccta tgcacgatct gattgggatg aacaagcggc
     1861 agcagttaag aatctggatg gacaggattt agccattttt gtcagttata caggagaaac
     1921 taaggggatt ttagcgtatg cacgtgtagc gcaggaacag caagtgccga tgattagttt
     1981 gatttcgact aaaggaagca ccttggaaaa attgtcgacg acgacgttat ttgccaaagg
     2041 gacgacacgt tatcatcagc gcgtagattt aagttcaaga attgctgtca tttgtttgtt
     2101 cgatacggtt ttattaatgt atgcagaggc aaagcagccg cggtaatttt atgcaacacc
     2161 atactaaatg atgtaagggg atacagaaaa agggtagcct cttttttctt tgttttgggc
     2221 tagttataat gagggcaatg aatgtaaacg caatcatttt tagttttgta aagaatgaat
     2281 ggaggagtta agaaatggca gtaaagaaaa agaaagcgac tttctgggag tttttccaag
     2341 gattaggtaa aacgtttatg ttgccagtgg ctttattagc ttttatgggg attttgttgg
     2401 gattaggaag ttctttttcc agtgaatcca tgattgaaac gatcccgttt ttaggaaagc
     2461 ccgcagtaaa aattattttc caatttatgt cgacaattgg tggttttgcg tttgcctatt
     2521 tacctgtcat gtttgcaatg gccattccgt tggggttagt tcggaaagaa aaaggaattg
     2581 ctgcgttttc aggtttcgta ggctatacgg tgatgaattt agcgattaat ttctatttag
     2641 tgcagacgaa tcgcctcgtg gatcctgagc agttgcggga agccggccaa ggaatggttt
     2701 ttgggattca aacgattgaa atgggtgttc ttggtggaat tatcgctggg cttattgtct
     2761 ataagttgca taatcgattt tatacggtgc aactaccaga tagttttgcc ttcttttctg
     2821 gcgcacggtt tgtaccaatt attacttcat tagtgatggc cttcgtgggc ttagtaattc
     2881 cgttagtttg gccacttttc gcgctaatga ttatggcgat tggccaactt atccaacgtt
     2941 ctggtatttt tgggcctttt ctgtttggtt caggggaacg tctactgtta ccgtttgggt
     3001 tgcatcatat tttggtttcc atgattcgtt ttactgaagc agggggttca gcggtggtgg
     3061 ctggcaaaga agtgtttggt gcgttaaata ttttctatgc agaattgcaa aataatttac
     3121 cgatttcacc aagcgcaaca gctttcttgt cacaagggaa aatgccgacc tttatttttg
     3181 gcttaccagc ggcggcactt gcgatgtatc atactgcagc tccggcgaat cgacataaga
     3241 ttaaaggctt actcctttcg ggtgtaattg ctacggctat cactggcatt acagaaccaa
     3301 ttgaattttt attcttattt attagtccat tattatggct gtttcatgtc attatgactg
     3361 gtctaggttt catggtaatg gctttattag gtgttgtgat tgggaacact gatggcgggc
     3421 tactggactt tgttattttt ggcttgttac aaggaactta tacaaaatgg tggtgggttc
     3481 tcattgtcgg cgctatctgg tttgttattt attatttcgt ctttaaaaca gtcattgtaa
     3541 cctttgattt aaaaacacct ggacgagaca aggtcttaga tgagactgaa tataccgatc
     3601 aagaagttca atataagaaa acgggtggct atgatgcgcc tgggatttta gcggctttgg
     3661 gtgggcaaga gaatattcaa gctattgata attgcattac gcgtttacgt ttagtgttag
     3721 cagatgctaa taaagtagat gatgacaaat taaagcaatt aggggcttta ggcgttgtac
     3781 atttagatgc gcagaatgta caagtgatta tcggaaccaa agtgacaacg gtccgtaatc
     3841 aattagagat gattttaggt tagaaaaaag acagaaggtg aagagtgtgt cgtttgataa
     3901 agcaattgat cgacgaggaa cgtattgtac acagtgggat tttgtagaag accgatttgg
     3961 ggaagcggac ttgcttccct tcactatttc cgatacggat tttgctgtgc cagaggcagt
     4021 tctggcaaca ttacaggagc gtttgaaaca tccagtattt ggctacacga ggtggaacca
     4081 tccgcaatta aaagaagcaa ttcaaacgtg gtaccagaca agattccaga cgaagattga
     4141 agaacactgg attatgtata ccccgaccgt tatctatggg atttctgctt tgattcaatt
     4201 attgactaac gaaggggagg gaattatttt acaaacacct gcctatgatg cattttttaa
     4261 agtcattcag gaaaataagc ggcaagtagt ggcgaatgaa ctgctttatc aagcgaagcg
     4321 ctacagcatt gattttattg atttagaaaa aaaactagcg caaccagaaa atcgctgttt
     4381 gcttttatgt tccccgcata atccaacagg acgtgtttgg gagcaatggg aattagagcg
     4441 aatggtttca ttgtgccaac agtatgatgt gtttttactt tctgatgaaa ttcatatgga
     4501 tatcgttaat aaaggccatg ttcatcgacc aattacgcaa tttaattata aaaaatctgc
     4561 tattattacc agtggcacga aaacctttaa ttttccagga ctgatttttg cttacgcctt
     4621 aattccagat aacgaattgc gtgacgcttt tcagctcaaa ttaaaaaacg ccgatggtct
     4681 atcatcaaca agtattttgg gaatgctagc aaccatgacg gcctatcaaa aatgtggtac
     4741 ttgggttgac gagttgaatg attatttagc ggagaaccaa cgttacgtga aagatttttt
     4801 acagacatat ttgccaaaaa ttaaagtgac ggagctggag gcaacttact taatgtggtt
     4861 ggatgtatca gcggcagttc cagatgtggc ccgcttacaa gaggctttag tttctgtggg
     4921 gaaagtcgcc attatggacg gctcgatata tggtggtaat gggcaacgat ttttacggtt
     4981 aaatattggc tgttcgcaag caaaactaca cgaaggactt gaaaggatgc gccaaggttt
     5041 tgaagctgtt ttacaaaagg atggcacagc atcagcgctt gggaataatt gagaaaagat
     5101 agcattccga aaatggttgc agtacaatgg aaaaatagaa acaaataaaa taacaaaaag
     5161 taacaacttg tcatttactg ggggaaaaga aatgaaaaca attaaaacaa agcaagcacc
     5221 acaagcaatt gggccatatt cacaagcaaa aattgtgaat ggtttattga ttacttctgg
     5281 tcagattcca ctggatcctg aaacaggcaa ggtggttggt acaacgatta aagaacaaac
     5341 caatcaagta ctgaaaaata ttcaagggat tttaacagaa gctggtagtg attttgctca
     5401 tgtagtcaaa acgacatgct atttacaaaa tatggcggat ttcacggcat tcaatgaagt
     5461 ctatgctgaa tattttagtg cggaatatcc tgcacgcaca acgattgaaa tctctaaatt
     5521 accgatggat gtgttggtgg agattgagat tatcgcagaa gtagtggcgt aaaaaataca
     5581 gataaaagag tgagaaaaaa atcgtcttag atttttttct cactcttttt ttcaataaaa
     5641 caatacgatt cagccaaaat gtctagccgt gctggaaaat tttcagcaaa taggctacca
     5701 tggaagaaaa tcgataaaac gaaagttaaa tgaatagaaa agagatatga aagaggctat
     5761 aagatgaaaa aaaatattag ccaactaacg cagtggttga aagaacacag tttattattg
     5821 aaactaattt ttcttggttc tgtattagtt ttcgtggcta accaagtgac acatatcgct
     5881 caaggcatga cctgggcgga tattttttcc acgatggaac aacaaagtac ggggcgttta
     5941 attggtatgg tcttggcagg actattaggg gttattccga tgctccttta tgactatgta
     6001 gtcgttaaat tattggaaaa agaaggtaag ccaccaatga aacgaatgga ttggttaact
     6061 tcggcttggg tcactaatac cattaataac ttagcgggtt ttggcggcgt ggttggggca
     6121 acgctacgga ttaattttta cggaaaagat gtaccgcggg gcaaggttgt agcaacggtc
     6181 tcaaaagttg ctctgttctt gatttcaggg ttatctattt tatcttttgt ggcgtttgtt
     6241 gatttatttt ttattcgaac ccaaaatgtt tttcgtgaat attgggtttg gttattattg
     6301 ggcagcctga ttgcgccagc gctctggttt ttcacgtact taaaacggcg aacattgttt
     6361 aaaacatttt ttccaaaagc ggtgctccta ttattcggcg cttcattagg tcaatggcta
     6421 ggtgggatgt ttgctttctt aatgataggt cgtttgatgc aggtgccagt ttcgatggtt
     6481 tctgtttatc caatgtttgt tatcgctacg ttaatcggga tgttaaccat ggttcctggt
     6541 ggtatgggaa cgtttgatgt cttaatgatt ttgggcttgt cacaattagg gattgatcga
     6601 tcacaagcgg tcgtctggtt gttgtattat cgtttgtttt attatgtgac gccttttatg
     6661 acaggagtta ttttgttctt gcaacaagca ggcatgaaag ttaatcaatt ttttgataat
     6721 ttacctcggt tattttcaca aaaagtggcg cattttattt tggtggcggc gttatatttt
     6781 gcagggatta tgatggttct attgtcgact gtgacgaatt tgtcgaatgt cagtcgttta
     6841 ttccaagtgt tacttccctt ttcttttaat tttttagatc aaacattgaa tttatttgta
     6901 ggattcttgt tattaggttt agctcgaggc atttctatga aagtgaaaaa agcttattgg
     6961 cctacaatta ttttactagg attttgtatt gtaaatacgg tggcacgaac gacttcgtgg
     7021 cagttaattg ctgtttatgc tgttatttta ttggcggtta ttttggctcg taaagaattt
     7081 tatcgtgaaa agtttgttta ttcatggggc gctttaacgg tagatagtat cttgtttggc
     7141 tgcttgttta tcggttatgc ggttgctggt tattacgccg cacgaccagc tggtggcaat
     7201 caagttatca atcacttttt gttgtttccg tcagatgatg tttggtttaa cggattgatt
     7261 ggattaagta tttccttgat tggtttattc tttttgtatc aatatttagc cgaaacaact
     7321 gttactttag gtgagggatt tgaggaagcg cggttgacac gctttttgga aaaatttggt
     7381 ggcaacgaag gcagtcaatt tttatattta aaggattatg gtcattttta ttaccaagaa
     7441 gaaggcgaag atcaagtact ttttgggttt caaatgaagt ttaataaatg ctttgtcttg
     7501 gcggatccga ttgggcaacg agagaaatgg acagcggcga cactggcgtt tatggatcaa
     7561 gctgatttgt taggttatca attagttttt tatcgtattt cggaagaata tgttatgaat
     7621 cttcacgatt gcggctttga atttatgaaa gttggggaag aaggcttgat tcaatttgat
     7681 gagccgtcaa cagtgaatca aacagcctgg acggaaacag taactgaaaa aatagcagca
     7741 gaagcagcgg attttcagtt tgaattttat cccgaaacga ttagtgatgc cttatatcaa
     7801 gagttagaac gagtttctgc ggactggtca cggaatcaaa aagagcgcta ctttattggt
     7861 ggacggttgg atcccgagta cttgaaatgc agtagcgtgg gcttggtgag acagaaacaa
     7921 acggtcatcg gtttcattac tggaaaagaa atggaaaaag gcaaaagtat ttcgtatgat
     7981 ttgttacgta ttcgttcaga agcacctgct tttactagag aatatttgtt cactcatttt
     8041 attgaaacct atcaacagca gggctatcaa ttaattgata ttgggatggc gccgttggct
     8101 aacgtagggg agagcaagta ctctttctta aaagaacgct ttgttaatat tttttacaag
     8161 tatagttatc aaatttatgc gtttcaagat acacgcaagc gcaaagaaca atatgtcact
     8221 agttggcaac cacgttattt tgcttatcct aagcggacca gtgtactctt tgcttttgtg
     8281 caactttctt tgttgattac gaaagggaga catcaaagtg tttcgcttgt ggaagaagca
     8341 atgactgaaa tttaaaaaaa tcacgcgatg acttaggaac tgacctaaga ttgtgagaca
     8401 ggaataaaaa agcattttcc tagactgctg atttccgata gtctatcggc gattggtagt
     8461 ctagtttttg ttgaattcga ctttcattat aataattaat gtattttttt acaatttcta
     8521 ttacaataga tgtaggttca tttgtgagcc catctaagta gaacgtttca gactttagtg
     8581 aggcatgaaa cgattcgatg caggcattat ctgaaggtgt ccctttgcgg gacatactca
     8641 tggtaatgcc ttttgttttt atttgattct ggtagtcaaa agaagtataa acagagccct
     8701 gatcactatg caatagacaa tccgttgttt ggggcaattg atcaagtgta tccagaacaa
     8761 aagccgtatc ttgcttatca ccgatggtat aggcgataat ttcaccatta tttctggctc
     8821 cacgtccttt ccaattcttt gtacttttta agcacctcaa tatgcatttt taaatagtta
     8881 ttttcatttc taagctgttg ttcatttgat agaatttctg gaccttttcc ataagcatat
     8941 tgttttccaa cgggttgaac cagacgatga ttctcgccat tacggtacca acgccaccat
     9001 gtttcaattt gtgttttgtt tttaattcct aattctgcca taattatttt tacaggaata
     9061 ttctcttttt tcatctgtat agccatttct ttgatgtgaa tcggataaga aactcgattt
     9121 cccattgaaa aagcacctcc tagttaaatt cattttaacg tgaattcaac aagaggtgct
     9181 tttttatttt gcctcagttt attgggtcag ttccgttcaa tgctcttcct ctttttgcat
     9241 agataagtta attaacaaac cataagagat taagtaaaaa gataaagtag aaaaaggttg
     9301 ttccgctacg gtgcagtagc ccttgctaca aagccaacct ttttggctgc tatattcaag
     9361 actgttcaat aaaacgttca tttcatattc ctacagaata tggaacgttt acctctaagt
     9421 ggcagcattt tacggacagc ataaaaaaag aaaagatttt gcccgactgg aacctttaaa
     9481 aagtttagca aagaggagga gaagttcatt gaaaatcaga agagagtatg acacgcatgc
     9541 aattgaaatc acacgttgga acaaaggcaa tttagtctat acgattgatt gtgattgtgg
     9601 tcgtcaagca gacagagtta ttggaatgta tgagacgttt attaaaaaat agaggtagct
     9661 acataaaggt tacctgcagc attaaaatgt agtttttata ccaattattt ataaaataaa
     9721 taaaacgaat aatttgtaga attaaactca tgctaatttg cttttctatt acactatttt
     9781 gtttctatat tctatttacc ccactaactc agaattcttg tttgaatagc ccattaattc
     9841 gagttctgat attttctatt taaactatac aatagaatct atttttgtat tatgtaggaa
     9901 atcaataatt aaacaaaaat gaaagggttt actattgaag gttagtgata tttaggtata
     9961 taattaatta ataaatatat gataaaagga gagtgctata ttggattatg aaaagataat
    10021 aaatcaatgc gaattagtta ttaaaaatca gacaacaaga aatattaatt cttatcatgg
    10081 attaagagac tacacttttt ttttaagttc tttgattaaa gttactccta acctttatga
    10141 attaatagaa gaaaaaatta taagaaatac aaactccatt gatgagtacg tagaaggaat
    10201 aattacaagt cctggattgt ggcatggttt atctagttac gggtatttat gtgcagaact
    10261 gaacgataat aaaaatctac agtattcata tgaaaaaaag aatcaaaaat taagcaatat
    10321 ggttgaactt ttatctaaaa atatagggga aattaaaata aaaagcttac agcaaatacg
    10381 taatcacaaa tggtttgata ttttctatgg agttacagga ataattgtat atttatttcg
    10441 tgttgagagg tttgaatctg caaaaaagtt aatatatatg ttaacagaca gtatactgtt
    10501 gacagaattt cttgatgtgt ataatagtcc attttcagaa aaaatagagg cgtattttcc
    10561 aggaaaattt gatcgtaatt ctggtaatat aataaacttg gatgtatctc acggcatatt
    10621 atctgtattt tttgttataa aagaagccca cataattttt ccaaatgatc aaaggatttt
    10681 tgatgcatat acttgtataa ggaattttta tgtttccata ttcaacgtaa aaaattcatc
    10741 ctatcataag caaattactg attattcgga tatcagaata tcaaagttca agtctaattg
    10801 ggctaggggg gatctaccat taattatcca actactatca gtcaaagatc cgttatttga
    10861 tatatcggat aacagagatt atttaaaaaa aaatattaat gatagattac taaaagaaca
    10921 agatgatatg aatttcaatt tttgtaatgg tattgcaggt gtaaatttcc aactgaagat
    10981 aataaatcaa tatttttatt tgaattattt tgaaaagtgt gtagatgaga agataataaa
    11041 tggattggat cagaaaattg acaaagagat tgatgaaaaa gaagatcaaa gattagtatt
    11101 taaaactatt aatgatatga acattataga tggttcattt tcaattatag tgcctaaaat
    11161 actgtcaaat cattatagtg atttgacaca aaccttcatt gcgaaaatgt tttgtattaa
    11221 atgaaaggag aaaatagtga aaaaaacata ttttattgtt aagagaataa ttgagttatc
    11281 tataactctg gacaaaaaac atctaatttc atttttttta gttaacatta taaagcttat
    11341 cttcccttta cttatcatga ttaatacaca gactatagtg aataatattc aaacgggaat
    11401 accatttcac tcgccagaat ttttttcgct aatcattcta ttcccgatat tgaatgtctt
    11461 ttcagaattg tttaataact taaatactta cttatcttca cgctactctg atattttaaa
    11521 tttcaaattt tcagaattac agttaaaaag tgtttttaaa cattctttag aagatttcga
    11581 gaatccagaa ttttatgatt taattcaacg tgcagaacaa gcaggaggtg tttatccatt
    11641 tcaaattatc atgactatgg tttcagtttc atctatttta ctaacgtcta ttagttatat
    11701 cattattcta ttaagatgga aatggtggac tattatttta ctgtttttgt ttccttttat
    11761 aagttctatt aaaacattaa ggcttagcaa agatgagttt actatcatgt acagtagaac
    11821 aaatctagaa cgaaaaagtt ggtattatgc taatctttta aacaaggatg aattctttaa
    11881 agagacaaca ctttattctt taggaaataa ttttttagaa gaattcacaa atttaagaaa
    11941 aaaatttatt aatgaaaaca aaaaaatgta tcgcaggcga aataagttta cttttttagt
    12001 ttcgttcata acaattttta ctacaagtat aatactatgt atagtatttt atgaagcatc
    12061 agtagggata atattaatag gctcgcttat gacatatgtc aattctatat caaccttaaa
    12121 aaataatttt tcaagtataa ttaacagctt tttttcccta caccaacaat ccctttatgc
    12181 aaaaaatatt ttagatttgc tcgattataa gtctattcca gaagaaaaac caaatcatca
    12241 aaaaaaaata acaataaaac aaatcaatag catcgaactt aaaaatgtaa gctttaaata
    12301 tgtccaaagc tctagatatg ctttgaaaga tatttcactt aattttgaaa aaggtaaaaa
    12361 atatattata gttggaaaaa atggatctgg gaaaagtaca cttttaaaaa ttattttagg
    12421 tttttataat aattttgaag gtgaaatgtt aataaatgag attccatttt ctgacattga
    12481 tataaatagt tatagaaagt gtatttcagc agtttttcaa gattttgcaa aatatcaatt
    12541 taaaataaat gaaacaattt cactttctaa gaatagagat attgatatga gggatatcaa
    12601 aaaagctgca tctgaagcaa atgcaagtca gtttattaaa caacttcctt ttaaatatga
    12661 acagcaactt ggaagctggt ttccaaatgg gattcagttg tctggcggag agtggcaaaa
    12721 agtgtcaata gcaagagctt tctataaaga taacgcttca ttagttgtat tagatgaacc
    12781 tagtagtgct ttagatccca tatctgaaga aaaagtcttt aaaagttata aatcattagt
    12841 caataacaaa attggaatct ttgtgactca tagaataaaa aatatagatt ttgagggaga
    12901 tattattgta ttgaatttag gaaagattag tgaatacgga aagcagtctg atttaataaa
    12961 aaaacaaggg ttattttacg aactttctac ggctaaaaaa cagttttaag ggggattttt
    13021 gtgatgaagt atatagtgtg tgatgatttt atttacagaa gagcagaatt ttcaatagat
    13081 tctttttttg attttttaaa taacgtctca aatgaagaaa tattaaaaaa agctaataac
    13141 gagtatagag aggttctata ctcgctatca tctaatttgt tgaaatcgct tgcaaatgta
    13201 aatatggata aggagaaact gtgcatagct ctatataaat atatatctcg atgtagctca
    13261 agagcaacac catatgcttt gtcagctaca gtaggtttag gtgaatttag tgaacagcaa
    13321 aattttaata tttctaaacg atttaaacat gataatattt tagtagacgt agatggtaga
    13381 tgggcatttg atgttatgag aataatggag gagaaattgt ttgatgactt gaaaattaaa
    13441 gtaaacaata cattgagatt tcatgaaaaa gatatagtaa atatttgggt aaccaatgaa
    13501 gataatagca atatctataa aaataatttg gtgattaatc gaactaaagc attagatata
    13561 ataatttctg ctgctaaaga tgaaacaact attcataaac tactcgaaaa actatctaat
    13621 gaatatccaa atgtaaataa tactgtattt ataaattttt tgcatgagtt aattaattca
    13681 gaaatattaa tatctgatat caggatatcc cttttagagc caaatataat aaataattta
    13741 gccaaagttt tgaagaaata tcatgttttt gaagaatcaa aaaagataat agagattaac
    13801 gaaatttgcc aaaactttaa ttgtaataca gaaagaaatt ttatcgaaaa agcagacatg
    13861 cttataggaa aaatgaagga tatatgtatt agtaaaaaat atctaaatat tatcaataaa
    13921 agtcatgatt gcttacacat tccacataaa tcaaagaaag agatctcaga ttttataaca
    13981 ttcataacca aaatatcaga gttactacct aaaccattga ataattataa aaatcagttt
    14041 gtggatagat atggttttaa tcttgctgtt ccaattttgg atgtttttta tgataaaaaa
    14101 ttgttgtttg atgacgatga aagacttgtt cgtgaaaatc agttatataa atcattgatg
    14161 agaaaaatat ctaatgggaa tattaactca ataatagata tatcgtacct tgtaagtaaa
    14221 tatgattata aaccaaaacg atatcatagt ggtatagaga tgagtttcta tctattgaat
    14281 aataatgatt gctttgaata tataatttct cctttagtgg gaagtgatgc tataggaaga
    14341 tcatttggta ggttcgattt ttattttgat aataaaatga gcaaaagaag gaatcaaata
    14401 ttgtctactt caccgcagta cgaaacagtt gatttaacgt ttttccctaa agaaaaaacg
    14461 ttactaaatg taatgaatgg cccaaaatct tcagaaatgc aatttaaatt tggttcaaat
    14521 gattttgaag aaaatttaaa tatccaattt gatgatatat atatttatct tgattcagat
    14581 ggcgattttc atttttttga tataaatagt gaaaaagaaa taattttcaa tgtaaataat
    14641 atggttaact taaattatgc gcctgagata gtaagatata ttatggcttt gagaagtaag
    14701 agcgaacccc aagtttttga tatatttcac gttttaaatg ccattggaac agatttaggt
    14761 tttttaccga agataacata taagaacttt acaattacac caaaaaagaa atatattttt
    14821 aaagatttag acaactttta caaagttggt ctagaaaaag gtttggaaaa aagaataatt
    14881 caagaattac tcaattgttt tccaagtgga agattttttt tagaaaatgg tgataatagg
    14941 ataattgtgg atatcaaaac agatattgga caaaagatag ctattaagga attagttaat
    15001 aatcaatgct tactagcatc tgatattcca tttaaagctg aatgtttacc tattaatgat
    15061 ggtaacaact catatgttgg tgaatttgtt tttcaaattt atagttctaa tgaacaaaaa
    15121 gtaagacaaa acaattttga aattatgaat actcgtcctt cagaatatag ttaccttcca
    15181 ttcgacaaat atttatatta taaaatatat tgttcaagac aaaatcaaaa tagactatta
    15241 cagatagaga taagcccatg ggtgagtaag ttaaaggaag aaggattaat aaagggattt
    15301 ttttatgtta agtataaaga tgaaaaagat cacttaaggt taagatttat attaaatgaa
    15361 tcaactaata tagaaaaact aacaagcata aatttgaatt ttttgaaaca atatgaaaaa
    15421 aaagaattga ttgatgatgt aactatgaat atatatgaaa gggaggttta taggtatgga
    15481 ggtaaggacc aactggatga gctagaaaat attttttcaa ttgaatcaga agtttttttg
    15541 aaatctatta attgtctatc ctatactgaa aaaaacttct tattctttaa tatagtatta
    15601 tattatttgg gaatatcggg agtaagtagt gaagaaatag ttgatatgtt aaaagtatac
    15661 aaaatgaaaa aagaacatcg caaagaattt ttaatttttt ttgatgagaa caacaatgag
    15721 aagattagcc ataacattga acaaatttta aaggagttta agtattatga agaggaaata
    15781 gcgatagcat tgaatcgagt aagaatgcat aattctagtg aaaaacgaaa tgaaatctat
    15841 ttatccatat ttcacatgtt acacaatcga ctaattggaa ttgacaggga aaatgaaaat
    15901 aaaattatgt cctttacaaa tagagaatat agaatagctt atgaaaaaaa gaagggggga
    15961 caaaataatg ggtaagattg cagttatttt tggaggtgga tttattagtc atataaatcc
    16021 acttaaaccc cttattaagc atttgaatga agaaaactat aaagtatatt tatttaacat
    16081 tgagaaatac aaagagatag tcgaaggttt aggttgcttt tttataaagt atccaaataa
    16141 aatagatgaa actaaatatc aagaaataga aattaaatat ctaaaagaat tggaacaaga
    16201 acaattaaaa ggaaatgtta tagaatatta taaattaata actaaaatag gagccataag
    16261 gtcacatact tttaatcatc gtatatttta taaactattt tctgatgtaa aaaaattaaa
    16321 tcctactata atattttgtg atgcaatcaa tatgtatggt gatttaattg caaaagaact
    16381 aggcatcgag tgcataggat atattacaaa taatatttat aattatagtt ttttaaacac
    16441 tgataatgga tacttgtgga aaactttttc tagacattgg ggaacgtctt atttttttga
    16501 taaggatttt ttttctaaat actgggaata tctatgtaag acatataaag aagtttcggt
    16561 agaaaataat ctcgaatatt tagaacctat gagacacttt gagccaagat caaaaaagat
    16621 tatcatattc tctagtaaat atatccagcc taaaagggct ctttgtaatg aaaaaagtta
    16681 cttttttata cctagtatag ttaataattt tgaaatcact gatactgagt taaaaaaatt
    16741 ttgtaaaggt atgaataaga ttgtatatat tgctcacggg tcttatttgg atgtaaattt
    16801 aaatcattat cttcctctaa ttaagatttt aacagaaaga ggaataaaga ttgttatatc
    16861 cacaggtaaa tatcatgcct cgtttattga aaaattacca aaaaaagtaa aattatcaaa
    16921 tttaatattt tgtgcgccaa ttattaatca gaaggatgca ctgttcatgt gtgatttgtt
    16981 tattacacat ggtgggatga acagtattat ggaagccata agttttgaaa cacctatgct
    17041 tttaaaccca ataaccccag aacaaaggat gaatgctttg attgtaaata ataaaaagat
    17101 cggcatttca aattataagt tacctagaga actgacgaca ggacaagcaa ttttaaaatt
    17161 acttgaacgt gaaaagtatg tgaacaacct tcataaattg aaattaaaaa ttttaaaaga
    17221 agtagaaaat ttagataaag aaaagctgaa tgaattttta aggaagtgat atagaatgaa
    17281 caaaatattt tcctattgtg gtagtgcaca agatatttct gtcactaata atgtcagtaa
    17341 agaactattg taccaactat caagcaaatt gaattcacaa gttttaatta aacactttag
    17401 atgcaaagat gtgaatataa attttgtgga taatcttaat caatttataa atcctaatat
    17461 tgctatgtct acaaatgatg atatggagat gctatcaaaa gagttgctgg cttctaaaat
    17521 agtgattttt tctactcctg tctattttaa aagtgtaagt gcgggtatga aaattttttt
    17581 agatagatta gtggggtgga ctcatacttt tgagcttaca ggtcgttacg gagtaataat
    17641 cgtttgtggt agtcaaaatg gatcagaaga gactgtgaaa tttttagagg acttcatgat
    17701 acgattaggg ctaggtacaa ttcaggtgat tgaatataat tctaatgaag attcagaaga
    17761 gtcgcttaga aaaaggatag aaatgatatc cgataatctt tctattagaa taaaagaaaa
    17821 tttagcaccc gagccaacgg aaatacagaa aaaaatttat agtgattata ggagggtgtt
    17881 tctttctgaa aatataaatc ctatagagca tgagatatgg cttgagaaaa ctaaagagaa
    17941 ccataattta gctgagctat ttaaattgaa ttatcataaa ttgtgatttt tttacgattt
    18001 ttattattgt ttgacagcgc tttcttgtag aggtaagatt atattataat atcggtcata
    18061 attaaaatga aaagaggatg aacaatggaa gatttaaaag attttgattt aaatattaca
    18121 caagaaacgc aagaaaattc gtcggtagat attcagccga gatcaacgag tgtcgtaagt
    18181 acagttattt ggtcaattat aggtacaagt gcggcgacta cacaatttgg tggagatcca
    18241 acttggactg aaaatagtaa gtgtcgttaa gttaattatt gtaatatagg tgttttagac
    18301 cggtatttat tgattcaaaa agaaagtggg acataagtca cttcgactta tgtcccactt
    18361 tctttttgaa tcaataacga aaagattaaa tttgctttat gaatatactc aatacaacaa
    18421 agtgtgtcgg atattgggta taatattcaa tttgctgttt cattaaaatg ttcatacagc
    18481 gaagtacctg aaataattaa atcagtaaca ttagaattat caatgacagg gatatttttt
    18541 cttgataaaa aagatacaaa ctgcggaagg aaatctttca cagaagagtc aaaatcaagt
    18601 ttaatagatt tttcattata atttaccatc aaataaaaat agtctggatt tatatcaaaa
    18661 ggggataacc ttgttttttt cgtatagatt atttctacag aacttaattc agaataagca
    18721 atttttttgg gatgtttaat tcccttaact aattcaacta gtttatttaa aacatttttt
    18781 gagtattggt gtatttctat atagttttgc tcgataatcc aatagtttgg aaacactgtt
    18841 ggaaaaacta aaattatccc taccaacatc atcaaaataa aaatccagat tggttgatag
    18901 ccgaatccag tgaacaataa agaaatcaaa gtccaaacta ataaaaataa gattcctttt
    18961 tttaaattaa actttttacc aattattcgt ggctttttaa aatatggact accttgaact
    19021 aactcatcaa ttgatacatt atacaagtcg gaaagaataa gtaaattatc aattgatgga
    19081 attgataacc cattctccca ttttgaaata gcttgcgttg ttacatgtac tttttcagca
    19141 atttgttctt gagtatagtg attattaatt ctgtaagttt ttaaaatatt ttgtattaac
    19201 ataatttgtc ccctccttga ttttagagta ttatattctt ctattatttg caatcaacta
    19261 gcggttgatg tgacaaaatg ctagttacat gcagttctgt tagaattacg caaattaaaa
    19321 tcatcatact ttttaaatga aaaacaatat gcactgttat gattttttgt aaaatttgga
    19381 tatactcaaa atttatattt actaatcctt aactagaagt attttatagt ataaaattta
    19441 catgtaaaat aattggccaa aaatagatgt aggttcattt gtgagcccat ctaagtagaa
    19501 cgtttcagac tttagtgagg catgaaacga ttcgatgcag gcattatctg aaggtgtccc
    19561 tttgcgggac atactaatgg taatgccttt tgtttttatt tggttctggt agtcaaagga
    19621 agtataaaca gagccctgat cactatgcaa tagacaatcc gttgtttggg gcaattgatc
    19681 aagtgtatcc agaacaaaag ccgtatcttg cttatcaccg atggtatagg cgataatttc
    19741 accattattt ctggctccac gtcctttcca attctttgta ctttttaagc acctcaatgt
    19801 gtatttttaa atagttattt tcatttctaa gctgttgttc atttgataga ttttctggac
    19861 ctgttccata agcatattgt tttccaacgg gttgaaccag acgatgattc tcgccattac
    19921 ggtaccaacg cccccatgct tcaatttgtg ttttgttttt aattcctaat tcttccataa
    19981 ttattttaca ggaatattct cttttttcat ctgtatagcc atttctttga tgtgaatcgg
    20041 ataaggcact cgatttccca ttgaaaaagc acctcctagt taaattcatt ttaacgtgaa
    20101 ttcaacaaga ggtgcttttt tattttgtct cagtttattg ggtcagttcc cttagccatc
    20161 gcgtgatttt ttatttgtct tcttttttac ggtttcgtct agctggaatc aaggttacgt
    20221 aggcaacgaa accaccagta catagaacga ataacacgat gccaggaatc aatccttctg
    20281 gtaaataaga gaactgaata gtatgggttc cagcgctgac aggaacgctt agaaaggcat
    20341 ctttaaaggc ttttggggta acttttttgc catcaatttt gacacgccaa cctttgtcat
    20401 aaggaattgt agtgacgagt acttgatctt tgtcggcggt aaaggtacct gaagcagagc
    20461 gtttgccagt ggttaaatca acgccttttt cttgcacggc ggaaatggct ttttcaaatg
    20521 cattggtatt taagccaact acttgcggct gaacaaaact tactgctttg gttccataaa
    20581 aacttacttt gaagttaacg gttgtatctt ttggatagta gcctaaatta taatattggc
    20641 cagtaatgcc aatttgtgat tgctgactcg agccgttcac ggtgaccgtc gcagtggaac
    20701 tttccaattg agcaaaatcc gttgggaata aactcaaata agcttgcgta ttggcgggca
    20761 cattgactgt ataagaaatc tctttggcta cgttatgttg tttctccgta aaagttacgc
    20821 cagctgtatt ttgcgtaatt gtcacgttat tttgaagcgt catcgttggt tgataaaagg
    20881 taaaataccg ttcattggta ttggctaaag catttagtaa atttgtttga ctacctaaat
    20941 tatcattgag aggttgccgg acattgtaaa tctctttgtc tgctaaaaat cctaacggca
    21001 aagcattttc gttgcgataa agctgatatt taccagcagc tgcttgtcgt tcaaagccga
    21061 atttcattgg attattttca gcaatattgt atttaatgcc catcaaagca tccattaaca
    21121 aggtattatt ttggtaacga atatttaaat tcgtgcctcg cgagcggaaa cctaaggcgt
    21181 ttaggtatgt tgaagaatgt cggttccgta cggaagaaaa catgctaatg ccactgtagc
    21241 catagttaat gccgtcattg gccgaaacac catttaaatt ttccaagcga taaaaagtat
    21301 cattttcttt ttttgtttga tagactagat tttttaagtc aggataaggt tcagaataca
    21361 aactacgtga tgcgtagttc caatcatcta aaataccagt gaccatcgcc cgtgtgttaa
    21421 tgattgcttc accagaaacg agcagcaata acaaaatcac taagtattgc ataggcgctt
    21481 ttttcaattg ataaaaagca atcccgaaaa agtataatag caaaaaagtt gccgttaata
    21541 cgaaagaggt taaagtcaca tacgtataac tagtagcacc ttttgtgccc attgcaagag
    21601 caaaaattgc taaaagaatc aaaatcaagc cgcttaagac gccgagatca tccttttcaa
    21661 atttttccca accataacca gcaagcaaaa taactaggaa tgaaaagagg aaactatagc
    21721 ggaaaagaaa catgttcggc gcatgcatac cgtgccagaa taaatttaag ggcgtgatgt
    21781 aaaagctagc aatcaatagg acaaacaaac tgccaaaaag tagtttgttt ttcaatggaa
    21841 tttctttcgt aacgaaatag aagagacaaa aaatcaaagg caacaaccca atgtaaataa
    21901 aaggaatgga cccatatttg gttgtatcgt aaacgccaat catatttttc ataataatat
    21961 ctaaaaaggc agtcgcttct gttttaaagg ttgtaatttc agaaagagtt tcaccattgg
    22021 ttcgtaaatc taagacagca ggtaagacca taatcatgga tgctccacca gctaaaagag
    22081 aagtagtaaa atatgcaacg attcgagatt tatatcgttg ccagtctgta aacgttcgtg
    22141 caaaatagta caggaaggaa aacaacccaa tcataaagcc aaaataataa tttgtaatga
    22201 aaagcaagaa ataactgaca aacaataatg tcggttttcg ttggtccatt aaacgatgaa
    22261 ttcctaaaat tacgagtggc agataaataa aggcatccag ccacataatt aattctgaat
    22321 gggccacaat gaaggacatt agcgcataag acacacttaa agtcacatgg gaccatttag
    22381 gaatcttaaa ggtttgtttt gccaagaacc aaaaactcaa gccagcactc ccaattttca
    22441 ataacgttag gaaatagagc gcatcaggca tgttttgatt gttaaagaaa aagacgagcg
    22501 gcgtaaataa gccaccaaga taataggaaa ttaaggacaa gtagtttagt cccaaagaag
    22561 cattccacgt atagaaaaga ctttgttttc catgaagaac attgttaaag cttgcgtgaa
    22621 aatttgaaaa ttgagaaaag gcatcgctgg ctaaaacact gcgactactt cctggataaa
    22681 tcccaatact caaatagata attgccataa ttaaaaatgg aatgaagaaa ctggctaaca
    22741 tataaggcca gttgtttttt aaaaactgcc tacttttatt tttcataaat aacctcacct
    22801 gatttttcga aagtacctat agtttatcat actctttatt tgatgtacca atagaagaaa
    22861 aactttaaaa ttttattagg atcctaagga tggagtgaag aagaattagg agtaagggat
    22921 tgacattcaa atgctaaatc accacatcaa acaacgaata ttctccgaaa aattgctgaa
    22981 aacaccctgt ggataacttt gtgcataact ctgttgaaaa ccacaaaaaa gctttttatc
    23041 tcggtttatc cacaaggata agttttcgag ttgctaaaaa aaatagacgc aagttcagaa
    23101 gtcctgcttg ctaaaagtaa aggagcccct aaagttgaaa gaagatgaaa acgttattaa
    23161 aacaacgttt tcatcttctt ttttctagaa tttacaaaga tttaatgtcg aacaaataag
    23221 cactgtggaa aagttttttg gaaaaaacaa gaaatttcat ccacaaagtt ttctgtggag
    23281 aatttaaaaa tgcttgtcaa gctttttttg aaaaaatgtg gataactttt taaagacaca
    23341 cttttttcca tttgcgaatt tgcgttcgga aactagtaaa aggggcaacg ctattaatgt
    23401 gaatccattt ccaaagaggc cattgtgctt tggtggtcgc ccaagcccgt tgttgaggta
    23461 aaaataattc gtcttcggaa agcgagtcaa tccaatgaag taatttttct aagatgtctt
    23521 gcaacgcaat cagctgactt tctaaactca tttgtccata ggtttgataa aatgattgat
    23581 agagagcgcc cagttgattc catttatagc cttcagctgg cgtttgaacg gtcagaccac
    23641 gttgttcttg ttcttcccaa gaaagcagca agttgagcca gcctaattga taggctaagt
    23701 tctctgaagg tgttttagct actgtttcaa ttcggtgatc tttaagtgtt tcaggaattt
    23761 ctgcaaattc agctaaatat ttttgtgaag ctatttgaat ggcctcaatc aaggcttttt
    23821 ttgattcata ggttcgcatt cttcggctaa cttcctttct tggtaggatc tgcttgtttt
    23881 tcttgagtaa tttgagtgac taaaccaaaa ggatctttca caatcgcata aaatgttgca
    23941 aattcatttt caattggttc ttggataata caggattcgg gagggcgcgt gagtttttca
    24001 aaaattgttt tggcagagtg acggctattg acggttaagc tgagggtcaa ttgttctgtg
    24061 ggcgtggtat tcattcctgc aaacaaagga ttatcagcta gttgtaattg aaaagtgtcc
    24121 atttgtaaaa tcgagtgaga aagccagtgt tcttcgccag cgggaatggt caaagaagga
    24181 tttaagcgct ctttaaattc ttgattagta attttaaaaa gaatatcacc agcaaaggct
    24241 tcttggtaaa acgtcaaggc ttccgttgct cgtccgttta agaccataaa aagggcaaat
    24301 tgtgtgtttt tcattgtttg aacctcctaa gattgataag ataagcataa caataaaagg
    24361 tgtcaaaaag tgacaccgat ggaggggaaa atgaaaaaat cagaacgttt aaatcaggaa
    24421 ctttttttct tgagaaccca tcctcagttt aatttaaatc agttaatgaa aacttttggg
    24481 atttctaaaa gcacagcttt gcgggatatt gaagctttgg aaaatttagg cgtgccgcta
    24541 tatgtggaga atggtcgtta tggtggctat cgagttttaa acaaaccgtt gttgccgccg
    24601 atttatttta acgaaaatga agtgttagca atcttttttt cgttacaatt actgaaatta
    24661 gtcgcagagt caccgtttgg tcattcctat cagcaaattc agcaaaaatt attgcattct
    24721 ttagatgaac caacccaatt taaaatcagt caaatgagta aggtcgtcta ttacgaagga
    24781 attgaacaag tagaagcacc aggcaattta gagcagctgt ttcattgtat tttggcgcaa
    24841 caagtaattc agtttaacta taccagatat gaagcaacaa cgaaaaaaat cttaccaacc
    24901 cggttaacta ttttagaagg gtattggtat tgttcaggct atgatgtgac taaaaaggct
    24961 tggcgtactt accgctgtga ttttatggag gctattcagc aattaaacca aacactggat
    25021 tttacgactg aagaattgaa agaatcgtat cgccatcaac aaacgacggc acgtacgatt
    25081 ccatttaaag caatcattac agaaaaaggc aaagaatttt tttataaaca tcgctttgac
    25141 aatattcagt tggaagaaac gcccacgcag tgttttttag ttggacagat tcatccaaca
    25201 gaaacacaat ttttagccaa ctattttatg ggctttggtg aagaagtgac aattttagag
    25261 ccagtccaag tgaaacaagc atatgtagaa agtataatga ggattcaaaa aaaatatcaa
    25321 gaatagattg tggaactgtg aacaatctca tgtgtaaaaa tgcacattgg agaggagaaa
    25381 gaaaaaccct tgatttttaa atcaagggtt tttctttcta agaacgtgct tgcccatttc
    25441 cataaataac atattttgtc gaagtaagct ctgctagacc cataggtcca cgggcatgta
    25501 atttttgcgt actaatgccg atttcggcgc caaatccaaa ttcaaaaccg tccgtgaaac
    25561 gagttgaagc attcgcataa acagcggctg catccacttg ttgtaaaaat tgttgtgtgg
    25621 caaagtaatt atcactaata atactttcag aatgttttgt attgtagcga ttaatatgct
    25681 ggatggcttc gtccaaagaa tcaacgactt tcactgctaa gataaagtcg agaaattccg
    25741 tttcccaatc ttgttcagtc gctggaatgg cttcttcaaa aattgctaac gcacgttcat
    25801 ctgcccgaag ttccacgtga aactccttca aggctttttc aattgttggt aaaaaggctt
    25861 cagccacctc ttgatgaatt aataacgttt cggcggcgtt acagacagaa ggacgttgac
    25921 atttagcatt gacaataatt tcagttgcca ttgttaactg ggcgtctttg tccac
//
