LOCUS       NZ_CP011802            21610 bp    DNA     circular CON 10-DEC-2024
DEFINITION  Bacillus atrophaeus UCMB-5137 chromosome.
ACCESSION   NZ_CP011802
VERSION     NZ_CP011802.1
KEYWORDS    RefSeq.
SOURCE      Bacillus atrophaeus UCMB-5137
  ORGANISM  Bacillus atrophaeus UCMB-5137
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus.
REFERENCE   1  (bases 1 to 4064321)
  AUTHORS   Chan,W.Y., Dietel,K., Lapa,S.V., Avdeeva,L.V., Borriss,R. and
            Reva,O.N.
  TITLE     Draft Genome Sequence of Bacillus atrophaeus UCMB-5137, a Plant
            Growth-Promoting Rhizobacterium
  JOURNAL   Genome Announc 1 (3), e00233-13 (2013)
   PUBMED   23788535
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4064321)
  AUTHORS   Reva,O.N., Chan,W.Y., Mwita,L., Dietel,K., Lapa,S.V., Avdeeva,L.V.
            and Borriss,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUN-2015) Biochemistry, University of Pretoria,
            Lynnwood Rd., Hillcrest, Pretoria, Gauteng 0002, South Africa
REFERENCE   3  (bases 1 to 4064321)
  AUTHORS   Chan,W.Y., Dietel,K., Lapa,S.V., Avdeeva,L.V., Borriss,R. and
            Reva,O.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAR-2013) Department of Biochemistry, Bioinformatics
            and Computational Biology Unit, University of Pretoria, Lynnwood
            road, Pretoria, Gauteng 0002, South Africa
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Velvet v. 1.2.10; CLC Genomics Workbench v. 7;
            UGENE v. 1.14.2
            Reference-guided Assembly         :: NC_014639.1
            Genome Coverage                   :: 300-350
            Sequencing Technology :: Illumina HiSeq; Illumina MiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000385965.2-RS_2024_12_10
            Annotation Date                   :: 12/10/2024 01:39:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,109
            CDSs (total)                      :: 4,023
            Genes (coding)                    :: 3,861
            CDSs (with protein)               :: 3,861
            Genes (RNA)                       :: 86
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 1 of 162
            Pseudo Genes (frameshifted)       :: 94 of 162
            Pseudo Genes (incomplete)         :: 114 of 162
            Pseudo Genes (internal stop)      :: 22 of 162
            Pseudo Genes (multiple problems)  :: 63 of 162
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:50:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3604956
            Orig. end                         :: 3626566
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011802.1.
            Source DNA available from Oleg Reva (oleg.reva@up.ac.za).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21610
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="12"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21610
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21610
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11610](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11610
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(148..162)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(240..3926)
                     /locus_tag="D068_RS17470"
                     /old_locus_tag="D068_cds39480"
     CDS             complement(240..3926)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042126 - nitrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="D068_RS17470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39480"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_010790231.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHSQTTYEDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLITMWREALQTHKNPLEAWKSIVEHPEKAKAYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNHETERFIEYAKQYTD
                     FPFFVTLSKEDGAYTAGRFLHAKDIGRQTEHDQWKPAVWNERTNTFAIPQGTMGSRWDG
                     QKKWNLHMADEDTGEQIEPRLSVLGIEDEIGTVRIPYFSNEGNRVLERDLPIKKLNLNN
                     EDVYVTTVFDLILANYGVNRGIGQKSAASFDDAEPFTPAWQEQVTGIKREMVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIANAKDWEGAPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFDKNGIDLYKEAEKAGAKTTKDVADYVARQLQEKKLKFAIEDP
                     DDEANFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWHDQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAISDLAEEVEMEPVKEAVATPLLHDTMQEMAQPFGKINDWSKGECEAV
                     PGKTMPNIHVVERDYKQIFYKMTALGPNAALKPSGTKGMSWSIADEYESLKKRLGEITT
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLEDITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIRDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3992..4007)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    4020..4035
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.28"
                     /tool="antismash"
     gene            complement(4067..4543)
                     /locus_tag="D068_RS17475"
                     /old_locus_tag="D068_cds39500"
     CDS             complement(4067..4543)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014115540.1"
                     /locus_tag="D068_RS17475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39500"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_010790232.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKHLPMFNQVSLPIVETLLNNGKFIRCSSDQSPSFL
                     HSQSVYIVLKGSIHFIDSRLPEGSRAIAFWKKGDVFPIDQNGELLLSPFISVKTSEDTL
                     VLEIPFYKFKKIMTYHPQLQTNFLVMLQENLFFSYQLFLRYLHTSQDENVTPDS"
     misc_feature    complement(4601..4616)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4686..5405
                     /locus_tag="D068_RS17480"
                     /old_locus_tag="D068_cds39510"
     CDS             4686..5405
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="D068_RS17480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39510"
                     /product="YwiC-like family protein"
                     /protein_id="WP_010790233.1"
                     /transl_table=11
                     /translation="MKVLIPKQHGAWAMLLIPFCLGMVKGGPVLWHIPLFTGWLFLYLT
                     VYPITLAVKKKKTKDYQKWIFYYGIAACCSIIAVVIHKPSFIWLGFSLFPLFLVHVYYA
                     RRKNERALLNDIAGVLFFSTGGLASCWLGAGSLDGWAWFIFAQSSLFFIGSSFYVKSMI
                     REKNNKTFAYCSWGYHLLLPFLSISLGASWGALAFIPSSLRAWFLHGKERSIKTIGILE
                     IVNACFFFAVICIFLTR"
     gene            complement(5445..6161)
                     /locus_tag="D068_RS17485"
                     /old_locus_tag="D068_cds39520"
     CDS             complement(5445..6161)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="D068_RS17485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39520"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_003326506.1"
                     /transl_table=11
                     /translation="MNFLSVRKSDKDLLSQDLHQLLESISTKRKIEKNTFLFQEGMDAK
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKNDIVGELTLFTEEPRYMLSAKVLADGEVFV
                     INKNKLEKELVQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VKRSDGILINIALTNHDLAKFCAAARESVNRMLGDLRKQGIISIEESGKIVLHQRDYLR
                     CEIECENCPLDICNID"
     gene            complement(6273..7460)
                     /locus_tag="D068_RS17490"
                     /old_locus_tag="D068_cds39530"
     CDS             complement(6273..7460)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="D068_RS17490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39530"
                     /product="NarK/NasA family nitrate transporter"
                     /protein_id="WP_003326505.1"
                     /transl_table=11
                     /translation="MINRQNIQLSLQSCSLVAGFMVWVLISSLISQMSSDINLSAGDIS
                     LVTAIPVILGSLLRIPLGYYTNRFGARMTFMISFLLLLFPVFWISIADSVFDLAVGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGFINGIYGAGNIGTAITTFAAPVVAQSVGWKSTVQ
                     MYMVLLALFALLHFFLGDRNEKKVKVSVKVQIKAVYRNHLLWFLSLFYFITFGAFVAFT
                     IYLPNFLVQHFGLSPVDAGFRTAGFIAVSTLLRPVGGFLADKVSPLRMLMYVFAGLTLS
                     GIILSFSPSLGIYAFGALTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEAALASFVIVIWMYWQERMKTHTERNGHSVN"
     misc_feature    complement(7525..7540)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    7537..7552
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.89"
                     /tool="antismash"
     misc_feature    7543..7556
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.25"
                     /tool="antismash"
     misc_feature    7544..7557
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.87"
                     /tool="antismash"
     misc_feature    7545..7558
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.38"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="D068_RS17495"
                     /old_locus_tag="D068_cds39540"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="D068_RS17495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39540"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_010790234.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKDEIKAAVLKAGLAEESQIPNVILETPKDKTHGD
                     YSTNMAMQLARIAKKAPRQIAEDIVASFDKGKASIEKLDIAGPGFINFYMDNQYLTKLI
                     PSVLEAGEAYGETNIGNGERIQVEFVSANPTGDLHLGHARGAAVGDSLCNVLAKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKEMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VKEEESERQKFFREYGLKYELEKLRVDLENFRVPFNVWYSETSLYENGKIDKALEALRK
                     QGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYQKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNDNPVYYAQYAHARICSMLRQGEEQGLTP
                     AADLDFSAVNSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLAASLHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /locus_tag="D068_RS17500"
                     /old_locus_tag="D068_cds39550"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="D068_RS17500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39550"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_010790235.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIADDGKEEVIEFRTSGSYHVKQNKVYLSYYE
                     EHDLGKVKTIVKVSESEVFVMRSGAVKMNQRFVPGVSTIAKYKMSFGELELTTSTKSIQ
                     SDIGKERGRISIAYDMHVGDEQQHLHNMTITYEGGLDA"
     misc_feature    9868..9882
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.54"
                     /tool="antismash"
     misc_feature    9894..9909
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="D068_RS17505"
                     /old_locus_tag="D068_cds39560"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="D068_RS17505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39560"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 8.7e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="D068_RS17505_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="D068_RS17505_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10264..11610
                     /gene="albA"
                     /locus_tag="D068_RS17510"
                     /old_locus_tag="D068_cds39570"
     CDS             10264..11610
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="D068_RS17510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39570"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_010790236.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1047.5, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.4e-27,
                     bitscore: 91.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.8e-07, bitscore: 28.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 2.8e-07,
                     bitscore: 28.4, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.2e-07, bitscore: 27.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 6.3e-42, bitscore:
                     141.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.2e-19, bitscore: 69.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.2e-10, bitscore:
                     38.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.1e-08, bitscore: 32.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIEQMFPFISESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLN
                     KTAYELCMLMDGQKTAEQILECQCATYNESPEDHKDWYYEMLDMLLNKQVIRLTDQPEY
                     RRIATSGSSDFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSLEQFKKTADMLYEK
                     GVLTCEITGGEIFVHPNANELLEYVLKKFKKVAVLTNGTLMRKESLEILRAYKQKIIVG
                     ISLDSVHSEVHDSFRGRKGSFVQTCKTIKLLSGHGIFVRVALSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFDSALVHKLWKAQAPRF
                     SEHCKKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10279..10557
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_D068_RS17510_Subtilosin_rSAM_RRE.1"
                     /evalue="3.70E-29"
                     /identifier="RREFam018.1"
                     /label="D068_RS17510"
                     /locus_tag="D068_RS17510"
                     /protein_end="98"
                     /protein_start="5"
                     /score="91.9"
                     /tool="antismash"
                     /translation="MFPFISESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLNKTAYE
                     LCMLMDGQKTAEQILECQCATYNESPEDHKDWYYEMLDMLLNKQVIRL"
     gene            11623..11784
                     /locus_tag="D068_RS17515"
                     /old_locus_tag="D068_cds39580"
     CDS             11623..11784
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="D068_RS17515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39580"
                     /product="bacteriocin biosynthesis protein AlbB"
                     /protein_id="WP_003326500.1"
                     /transl_table=11
                     /translation="MSPTQRKWLLYILSFVFVIGAVVYFVKSDYLFTLISIVIAIIFGM
                     RARKAESR"
     gene            11781..12500
                     /locus_tag="D068_RS17520"
                     /old_locus_tag="D068_cds39590"
     CDS             11781..12500
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="D068_RS17520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39590"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_010790237.1"
                     /transl_table=11
                     /translation="MSMLDIHALSVWYEQDNVILENVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGSFKLCGIEVNAKTPLKTSDQLKTNRYFAADYPLLFTEITAKEYVS
                     FVHSLYQKEFHEQQYVSLAEEFHFSQYTNRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYEKMQEYCKAGGTILFSSHLLDVVKRFCHYAAILHDKQIRKLIPI
                     KDDTDLRREFFEVIGHE"
     gene            12493..13821
                     /locus_tag="D068_RS17525"
                     /old_locus_tag="D068_cds39600"
     CDS             12493..13821
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326498.1"
                     /locus_tag="D068_RS17525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39600"
                     /product="hypothetical protein"
                     /protein_id="WP_010790238.1"
                     /transl_table=11
                     /translation="MNNVFQILSLLFKQLYGRQGKKDAIRITAGLAVLALFEIGLIRQA
                     GIDESVLGKTYVTLALLFMNVYMVFISVSSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGTGTLSGTETLFWIGKFSFFTVYSILLGVLLSNLFVKKKG
                     FVFLLHAAAFACICASVVFMPAVTIPLCGVHMAWGVFFDFPSFLQVPHQQNKMHSFMRT
                     SEFSFYKREWNRFISSKAMLLNYIVMAAFSGFFSFQMMKTGIADQHIIYIVITALLLIC
                     SPIALLYSLEKNDRMLLITLPIKRRTMFWAKYRFYSGLLAGGFILIAMIVGLISSQPIS
                     VMTFLQCIELLLMGAFIRLTSDEKRPSFGWQTEQQLWSGFSKYRSYVFCIPLFLATIAG
                     TVISLAIIPIAGLIIVYLLQKQEGGFFDTRRKSERFGNEPVND"
     gene            13769..14959
                     /locus_tag="D068_RS17530"
                     /old_locus_tag="D068_cds39610"
     CDS             13769..14959
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326497.1"
                     /locus_tag="D068_RS17530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39610"
                     /product="insulinase family protein"
                     /protein_id="WP_035175322.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 2e-06, bitscore:
                     25.8, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQGEKVNDLEMNLLTTDQFSTISIAASFLKPIENAAEPEEETIY
                     FYGAAAYLKQNITDIFGYAAGSRFIYSANLFFDRQLKTYGTRLIHPLYHKNLNIDDVLE
                     AFVDRSSLPASLPADIAETAKADLLLKIEKKFADPFSYSAARLAEETFGSPMYGTAMFG
                     RKEKVQAIQPKRFLDASDFKTDLLSQQKQLYVIGNVQELHAGGYSRHAPSMNGRRKPVN
                     KNIYETETRSTAGPSVMTLGFDCGEMNGFRDYIKIQLIDGLLGKYGHSALFRHFREKQM
                     AVYHVITRYDIMSNLLLVSVCTNRVQEKEIPPRVIETVMNFHVDEQELEKAKQFLKNEI
                     LLQLDSPEGLLAYMGILRHYSYKKEDILDGISTITCRDLLQYVTNIEYIGAHVVRG"
     gene            14965..16242
                     /locus_tag="D068_RS17535"
                     /old_locus_tag="D068_cds39620"
     CDS             14965..16242
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015483836.1"
                     /locus_tag="D068_RS17535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39620"
                     /product="pitrilysin family protein"
                     /protein_id="WP_035175327.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.3e-12, bitscore:
                     45.0, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKETFFHQLDARTEITYADNGLKICRVKFPNAHMRLCNVKVDFG
                     SRDIRLHSGDSEKVLPYGTAHFLEHVLFWHNGRNLYSDFFDHGALLNAFTTYTDTNFMF
                     TSLPDRLEHTIPKLLDALWNPSFDENIVAQEKSLIKSEIEAAHLNQQLHYHYQMLNLLS
                     PASPAAIFPAGRTEDIEALTINDLKEAYATGYQPQRMTMFLIGGSEDTETILPSHLRLR
                     GRSGHTAKRKFMPACPPLLQNQSLGDAECSGETWTGLHIGVLPDKNDLFTLQMYWDIVS
                     RVLFHIDSPLFQEIRQTRLLNIQSLSAESHVSEDGGFLILHSKGAHSSAYIDVATYYVM
                     QQKCQAEAWLEYGKESLLNAIIYDSDYVRKCFEWAAECERYDCSFFELYRLIQNMTVQD
                     FLYLIDTVASAKKATIHVSHPEVVGQ"
     gene            16239..16940
                     /locus_tag="D068_RS17540"
                     /old_locus_tag="D068_cds39630"
     CDS             16239..16940
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015250988.1"
                     /locus_tag="D068_RS17540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39630"
                     /product="hypothetical protein"
                     /protein_id="WP_010790241.1"
                     /transl_table=11
                     /translation="MKKSTVFTVLLLLMVMAAHSFGWFQASAEAAGQYVQLIKNDYVRL
                     GLLSCAASVLMLPAFLYLHYVTRSVKSMTAAFQKITQSHQSCCDFQHRKLCSRYAGDVK
                     SLRESYKGIRQTYVMGAVLCQVIVFGYMFEVVKSIPFSFNAPPAVTKGLAIVLTIYLLF
                     YMRSYLLQLLQNGQTAKKAVVLLLAGAGIWWMLSFTMSELLFLIILAVIQQVGSFIYKR
                     VSYRSSASLDL"
     gene            complement(16947..18323)
                     /locus_tag="D068_RS17545"
                     /old_locus_tag="D068_cds39640"
     CDS             complement(16947..18323)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012118684.1"
                     /locus_tag="D068_RS17545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39640"
                     /product="YncE family protein"
                     /protein_id="WP_010790242.1"
                     /transl_table=11
                     /translation="MKKNDLSAFQENCFCFCDEEISREALFQVPIDIPEGFTIDSAEAA
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVQYAVRLQGTVTLLVSVSPVRNQYGQGDGA
                     VSVIHNAEIDQVVYYSDNPDDCPDFSDITIENLVVVPPFYGSPLSVTGTIVLVPAPDQR
                     SYVFTANTGDSTVSVIDTDVNTLVSTISLSDIPTDLGVTLDKAYTYVLHRNANLVSIIN
                     NETLTVTQTIPLAGAPRKIQFETGGGFAYILAGGSSIYEINISSQTITNTFTVSPAADD
                     FALDPNGQFFYTTNSVFWVVNKYDINTGQLIDSLSNFETPNLIETPLIGDFAYLENGEL
                     RPNVVSVIDLTTFSESSQINRLFDGLITIVFSADGTRAFFLEPYYDSFPENLTVVDTTL
                     HTFITTASLPGAIDLTVTPDNQYIYVAQPAANTVTVYRTSDYTAVAVIPVGAGPSAISI
                     "
     gene            complement(18363..19724)
                     /locus_tag="D068_RS17550"
                     /old_locus_tag="D068_cds39650"
     CDS             complement(18363..19724)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326493.1"
                     /locus_tag="D068_RS17550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39650"
                     /product="YncE family protein"
                     /protein_id="WP_010790243.1"
                     /transl_table=11
                     /translation="MNKIERSFKEKAVRQQEDCLCFCEEEASREAMFQAPIEVPEGFVV
                     DPAEAVANVTWNADSLSCVSERCFIQTGPGPDEIEIHFAVRLQGTVTLLVSVSPVRNQY
                     GQGEGAVSVIHNVEIDQVVYYSDEPDDCPDLSDITIENLVVVPPFYGSPLSVTGTIVLA
                     PEPEPEPVYAFTANPDDQSVSVIDTNTHTVITTISLPYEPTGIEITPDKASTFVLHLNN
                     SVISVIDNGTLTVTASIPLDQPPETIKFMPEHDFAYVLAGNAIYVIRIETSAVERSIPV
                     EGYDIAIDPNGMFAYVLDFGLVQKVDLSTGEVTGTIERELIVNSIETKPPERYAYVLEE
                     DHFFNYLTIIDLDTFTISSTQELEYEGEYLMFKSGSGVYLFDGFTHNLYSVSPSGAGII
                     GNLPQSARDFAFTPNGEFLYATHFIEQSITVYNTDDYSVETVISLGVSPSDIAI"
     misc_feature    19821..19830
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            20007..20561
                     /locus_tag="D068_RS17555"
                     /old_locus_tag="D068_cds39660"
     CDS             20007..20561
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326492.1"
                     /locus_tag="D068_RS17555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D068_cds39660"
                     /product="YdhK family protein"
                     /protein_id="WP_010790244.1"
                     /transl_table=11
                     /translation="MKRNTTLTGIVSLLLLLMLSACGSDNQDKKSDQTMNMDDTHTHSE
                     SSEIPEGLTAAQHPTYKVGSQAIIKADHMKGMKGAEATITGAYDTTAYAVSYTPTTGGT
                     RVENHKWVIQEEIKNASDETLKPGTDVIIEADHMKGMKGATGKIDSAEKTTVYTVDYTP
                     TTGGEKVKNHKWVTESELSSK"
     misc_feature    20725..20741
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     misc_feature    21136..21149
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.52"
                     /tool="antismash"
     misc_feature    complement(21197..21210)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.06"
                     /tool="antismash"
     misc_feature    21236..21249
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.37"
                     /tool="antismash"
     misc_feature    21563..21572
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
ORIGIN
        1 gacggttggt tttcggtcct gatttcagct caagctttcc tttttttaat gtccagccgc
       61 ctttatattt gtcttggtcc tcccactgct tcggatagcc gatgccaggt tttgtttcaa
      121 cattattgaa atacatatat tcggcaccgg aacggtttgt ccatgtgttt ttgcaggtca
      181 cgctgcacgt gtggcagccg atgcatttat ctaagttcat gaccattccg atttgcgctt
      241 taatcttcaa gccaatcgac ctccttcagc ttgcggatga ccacattcag atcgcgctga
      301 ttccccgtag ggccatagta gttaaagccg tagctgagct gggcatagcc gccgatcatt
      361 tgtgtcggct tgacgtgaat ccttgtcgga ctgttatggg tgccgccgcg gttattcgtc
      421 agttttgtgc cgggtacatt gatgtggcgg tcttgtgcat ggtgcataaa cgccatccct
      481 ttaggaatac ggtgagaaag aacggctctc gctacgacaa cgccatttcg gttgaagcat
      541 tcaatccaat cgttgtccct gatatctgtg tcctctgcat catctttatt catccacact
      601 gtcggccctc cgcggaatag cgtcagcatc ggtaatgaat caaagtacat gctgtggacg
      661 gaccatttgt tatgcggcgt taaataattg agaacgattt ctttgccctc ttgatcaggc
      721 cgtttactca gaaacggacg atgctggagg atcggtttaa atgtcgccat cgtttccccg
      781 aactccatca tcagctcatg atcgacatag taagactgtc tacccgtcag cgtccgccaa
      841 gggattaatt tttccacatt tgtcgtaaac ggcgagtacc tgcgtccccc tttttctgag
      901 cctgtaaatg ccggagacgt gatgaccgtt tttggctgag cggtgatttg ttcgaacgta
      961 aagcattctt cttcccgctc ttcagccagg tcttttaact tcaggtttgt gatgtcttca
     1021 agtgattccc atgctttcac cgcaactttt ccattcgaag tggaagaaag ggttaaaatg
     1081 gcttctgccg cctgcttcgc ctcacttata ttcggacatc ccttggcgac gctgtccgtt
     1141 gtgatttctc ccagtctctt tttgagtgat tcatattcat cggctatcga ccagctcatc
     1201 ccttttgttc cgcttggttt tagggcggcg ttagggccga gtgcggtcat tttataaaag
     1261 atttgtttat agtcccgttc aacaacatga atgttcggca tcgttttccc cggaacggct
     1321 tcgcattccc ctttgctcca gtcattgatt tttccgaaag gctgcgccat ttcctgcata
     1381 gtgtcatgga ggagcggcgt cgcgacagct tctttaaccg gctccatctc tacttcttca
     1441 gccaagtcgg atatggcttt tgataatgct ttaaaaatat cccagtctga cttggattcc
     1501 caaggcgctg agatggccgg agcaaaagga tgaataaacg gatgcatatc cgtactgctg
     1561 agatcatgtt tttcatacca agtcgccgcc ggaagcacga tatcggaata caatgccgtt
     1621 ccagccattc gaaaatcgag attaattaat aagtcgagct ttccttccgg tgcttgatca
     1681 tgccatttga tttcttccgg acggatgctg tcgctgtcgt cattcatcaa tccgtttgtc
     1741 gtccccaaga gatgcttaag aaaatattca tgcccttttc ccgaacttga gatcagattc
     1801 gctctccata caaaaagatt tctcgggaaa ttggcttcat cgtcaggatc ttcaatggca
     1861 aatttcagtt ttttctcttg aagctggcgg gccacatagt cagcaacgtc ttttgttgtc
     1921 ttcgcccccg ctttttcagc ttctttgtac aggtcaattc cgtttttgtc aaatgtcgga
     1981 taagacggaa gccacccgag tcttgccgcc agcacattgt agtcggcgtg atgtttatat
     2041 cgggaggatg ctgcgatcgg agaagccaag tcactgatcg gctgatcctc gtagcgccac
     2101 tggtctgtcg caaagtagaa gaatgatgtg ccgttttgca gctttggcgc cccctcccag
     2161 tcctttgcat tagcaatcgt ctgccagcct tcagccgggc gaagcttttc ctgccccaca
     2221 tagtgagccc atccgccccc gtttacacct tgggcgccga ctaataaaac aagatttaaa
     2281 accgcccggt aaatcgtgtc agagttgaac caatggttaa ttcccgcccc tacgataatc
     2341 attgaccgtc cgtctgtatc gatcgcattt tgggcaaatt ctctggcaat tttaacaacc
     2401 atctcccttt tgatccctgt cacctgttct tgccaggcgg gtgtaaacgg ctcagcatca
     2461 tcaaacgagg cggctgattt ctgcccgatt ccccgattga cgccatagtt tgccagaatt
     2521 aaatcaaaaa cagttgtgac atatacgtct tcattattca ggtttagttt cttaatggga
     2581 agatcgcgct caagcactct gtttccctca tttgagaaat aagggattcg aactgtgccg
     2641 atttcgtctt ctattccgag cactgacagc ctcggttcaa tttgttcccc tgtatcttca
     2701 tctgccatgt gcagattcca tttcttttgg ccgtcccatc gtgatcccat tgttccttgc
     2761 ggtatcgcaa atgtgtttgt acgttcattc cacacagcag gcttccactg atcatgctct
     2821 gtttgccgtc cgatgtcctt cgcatggaga aaacgtccgg ctgtataagc gccatcttct
     2881 tttgacaagg tgacaaagaa cgggaaatcc gtgtattgct ttgcgtactc tatgaaacgc
     2941 tctgtttcat gattcacgta aaattcttgc aggatgacat gccccattgc catcgcaagc
     3001 gcgccgtctg ttccctgacg gatgctaagc cagtcatccg caaattttga cgattccgca
     3061 aaatccggac taattgagat gacttttgcc cctttatagc gggcttctgc caaaaagtgc
     3121 gcatccggcg ttcttgttaa cggtacattg gatccccatg tgatgatata gcccgaattg
     3181 taccagtcac tgctttccgg cacgtctgtc tggtctcccc agatttgcgg agacgctggg
     3241 ggaagatccg cataccaatc ataaaagctc agcatagggc cgcctattaa tgacataaac
     3301 cgcgagcctg acgcgtggct gatcattgac atggcgggaa tcggagaaaa tccgacgttg
     3361 cggtcagggc cgtatttcat gactgtatat aatagagaag cagaaatcag tttcagcacc
     3421 tccggccact cagcgcgcac aaaaccgcct tttcctctcg cctgtttata ggccttcgct
     3481 ttttccggat gctcaacgat agatttccat gcttccaatg gatttttgtg tgtttgcaat
     3541 gcttcccgcc acatagtaat cagcacaccg cgaacgtatg gatatttgac acgcagcggg
     3601 ctgtagatat accaggaaaa acttgccccg cggggacagc cccttggctc gaagtcaggc
     3661 atatcagggc cggttgaagg ataattcaaa ttttgccctt cccacgtgac gatgccgttt
     3721 ttcacataaa tattccagct gcaagatccc gtgcagttga ctccgtgggt ggagcggaca
     3781 actttatcgt actgccatct gtttctatat acattctccc aatcgcgatc ttcgtatgtt
     3841 gtttgactat gtttattaga atgatgctca ataggagaga aatagtttag tctcctgaac
     3901 agcggactca ttttcttctt tttcatcgat gcttcactcc tttgagtcag gtgattctca
     3961 tttcactata tacagaggca gcatcgttcc ttgtgaactt tgtcacatac gccccttatt
     4021 tcacaaatgt ttcacattca ggattcaaaa aaaacccggt tcctggttag gaatcgggag
     4081 tgacgttttc atcctgagat gtgtgcagat aacgtaaaaa taactggtag gaaaaaaaga
     4141 gattttcctg aagcatgacc agaaaattcg tctgtagctg cggatgatag gtcattattt
     4201 ttttaaattt gtaaaaagga atttccaaca cgagtgtgtc ttcagatgtt ttgactgaaa
     4261 tgaaaggaga taaaagcagc tcgccatttt gatcaatggg gaacacatca ccttttttcc
     4321 aaaatgcaat ggcgcgcgat ccttcaggca gtctgctgtc aataaaatga atgctgcctt
     4381 ttaatacaat ataaactgat tgtgaatgca aaaaagatgg agactgatca gatgagcaac
     4441 ggatgaactt cccgttattc agcaatgttt cgacaatggg aagagatact tgattaaaca
     4501 ttggaagatg tttcagaaat aataaatagt cacactgatt cataggaaag cctcctgtgg
     4561 taaggatagc tttagtgtat cttggttgaa tcaatacagc agtgatgtaa ttcacagaaa
     4621 ttatgataaa tgtcacttat cggaagaatg attgctttta taatgaaaca gaaaggagtg
     4681 tttcaatgaa ggtgctcatt ccgaagcagc acggtgcatg ggctatgctg ttgattccgt
     4741 tttgcctcgg tatggtgaag ggaggtcccg ttctatggca tatcccgcta tttacgggct
     4801 ggctatttct ctatttaacc gtttacccca ttaccttggc ggtgaaaaag aaaaaaacaa
     4861 aagactatca aaaatggatt ttttattacg gcattgcagc ttgctgctct atcattgccg
     4921 ttgtcatcca taagccttcg ttcatctggc tcggcttttc tttgtttccg ctgttcctcg
     4981 ttcatgtcta ttatgcccgc cgcaaaaacg aaagagcgct tctgaatgat attgcgggag
     5041 tcttgttctt tagtacaggc ggacttgcca gctgctggct gggggcggga agccttgacg
     5101 gctgggcatg gtttattttc gcgcaatcca gcttattttt tatcggaagt tccttttatg
     5161 tgaagtctat gatccgggag aaaaacaaca aaacatttgc atactgttca tggggatatc
     5221 acctgcttct tccctttctt tctatatctc tcggagcaag ctggggggct ctcgctttta
     5281 ttccaagcag tttgagagca tggttcttac acggaaagga gcgatctatt aagacgatcg
     5341 gcattcttga aatcgtgaac gcgtgcttct ttttcgcagt catatgtatt tttttaacaa
     5401 gataaaacaa ggactgaagt ttgcagtcct tgtttatttc ttgattaatc gatattgcaa
     5461 atatccagcg ggcaattttc gcactcaatt tcacatctta aatagtcccg ctgatgcaaa
     5521 acaatctttc cggattcctc aattgaaatg attccttgtt tacgaagatc acccagcatg
     5581 cgattgacac tctctcttgc agccgcacaa aacttcgcca aatcatggtt cgtcagtgca
     5641 atgtttataa gaattccgtc gcttcgtttc accccatagc tatttgacaa acgaatgagt
     5701 gtggaataaa gcgccccttt tttaccatga agaagaaggt cacggatttt ggactgaatt
     5761 tttcgcaggt gggtgctcat ccatttcata aattcaaatg tcaaagcacc gttttgaacc
     5821 aattcctttt ccagtttgtt tttattgatg acgaacactt caccgtctgc taacactttt
     5881 gcactcagca tatatctcgg ttcttctgta aaaagtgtta attccccgac aatatcattt
     5941 ttttggcaga tcctaagcgt cagatccttg ccgtcagacg tcagtttgcc gatttcaatg
     6001 agtcctgatt gaatcagata aagctctttt gcatccattc cttcttgaaa cagaaacgtg
     6061 tttttttcaa tttttctttt tgtactgatt gattccagca attgatgcag atcttgtgag
     6121 agaagatcct tatcagattt tcgaacagag agaaaattca tgagctcacc tcgaagatag
     6181 tcacgttgtg tatttctatt gtaacgtgaa tcgatttgca tcattttaaa aaaacttaca
     6241 atctcgtgaa ttccccaaac gtcggcttcc cattagttta cgctgtgccc atttctctca
     6301 gtgtgcgttt tcatcctttc ctgccaatac atccagatga caatgacaaa gctggctaaa
     6361 gcagcttccg agagcgccat aaatccgatt gcatattgtc ctgtcgcttg aaatacgctt
     6421 gccaggatca gtggcggaaa gaatcctccc aatcccccca tggcagaaac aataccgttt
     6481 gcaattcccg cttgttttga gaaataaaaa ggcaccaatt taaaaactgt tccgtttcca
     6541 attcctgagc agacagcaac tgttaacgcc ccaaaagcgt aaatgccgag actcggtgag
     6601 aacgacaaga taatgcccga taatgtcaga cccgcgaaga cgtacattaa cattctaagc
     6661 ggactcactt tatctgccaa aaatccgcca acaggtctga gaagcgtgga cacagcaata
     6721 aaacctgccg ttctaaaccc ggcatccaca ggactaagac caaagtgctg aacaagaaag
     6781 ttaggaagat aaatggtaaa ggcaacgaac gcgccaaatg ttataaaata aaaaaggctt
     6841 aagaaccaca acagatgatt tcggtaaacg gcttttattt gaacctttac ggaaactttg
     6901 actttcttct cgtttcgatc gcccaggaaa aagtgcagca aagcaaataa agccagcagg
     6961 accatataca tttgcaccgt actcttccat cccacagatt gagcaacaac aggagctgca
     7021 aacgttgtga tggcggttcc gatatttcca gcgccgtaaa tgccgtttat aaaaccgtgt
     7081 ttttccttag gataatactt cggaagagat gtcaccccaa tggagaaaac cgctcctcca
     7141 atccccaaga aaaaaccgcc cacggccaaa tcaaacacag aatctgcgat actgatccaa
     7201 aacacaggaa acagaagcaa tagaaagctg atcataaaag tcatccgcgc gccaaacctg
     7261 ttcgtgtaat atcccaaagg aatgcggaga agcgatccca gaatgacagg tatggccgta
     7321 accagcgaaa tgtcgccggc gctcaaatta atatcagatg acatttgaga aattaatgaa
     7381 gaaatcaaaa cccaaaccat aaatcctgcc accaagctgc atgactgtaa cgataattga
     7441 atgttttgac ggttaatcat tcggtttgcc cctttcaatg attcaataat cagtcttatc
     7501 atacaaaaac tcggtgaata ggattgtgaa gttcatcaca cgttttttta acaaaaaagg
     7561 acaaagccta gggctttgtc ctttcatctt cattacattt tttcaggagc cgaaacgcca
     7621 atcaactgaa gcgcattatt cagcgtgatt tgggttgctt tcattaaagc taagcgtgcg
     7681 cggcttttct cttcattttc aggatcgatt accttttccg cattatagaa gctgtgcaga
     7741 gaagctgcca agtcataaat atagttcgtc acgcggtgcg gaatgcgttt ttccgccgct
     7801 tccgccactg cttcagggaa gccgccgatt gttttcagca aatcgtattc tttttcagaa
     7861 ttgacggcgc taaagtcaag atcagccgca ggcgttaatc cctgctcttc tccttggcga
     7921 agcatgctgc agattctcgc gtgagcgtat tgcgcgtaat acaccggatt gtcatttgaa
     7981 gtggacaccg caagatccaa gtcaaaatcc atatgtgtat cggcactgcg catcgcgaag
     8041 aaataacgga cggcgtctaa gccgacttct tcaatcaagt cgcgcatcgt taccgctttt
     8101 cctgtacgct tgctcatttt cattttctcg ccgtttttat atagatggac gagctgaatg
     8161 atttctactt ctaacgttcc tttttgatag ccaagcgcct caatggccgc tttcatccgc
     8221 ggaatatagc cgtggtgatc tgcgccccag acgttgatca gcttatcgaa tccgcggtct
     8281 agcttgtcct tatggtaagc gatatcaggc agcaaataag tgtaagtgcc gtctttttta
     8341 atcaaaacac ggtctttatc atcgccgaat gttgttgagc ggaaccaagt tgcgccgtct
     8401 tcttcataca cgtggccttg tttgcgcagc gcttcgagcg ccttgtcgat ttttccgttt
     8461 tcgtataatg acgtttcaga ataccagaca ttaaacggca cgcggaagtt ttctaagtct
     8521 acacgaagct tttccaactc atacttcaag ccgtattcgc ggaagaactt ctgtctttcg
     8581 ctctcttctt ctttgacaaa gcggtcgccg tattcttcag cgagacgctt cccgattgcg
     8641 ataatatcct cgccgcggta tccgtcctca ggcatttctt tttcaaggcc gagcgcttca
     8701 aagtaacgga cttcgacaga aagcgccaag ttgttgatct gatttcccgc gtcattgata
     8761 taatattcgc ggctcacatc atatccggct ttagccagca cattgcacag agaatcgccg
     8821 acggctgctc cgcgcgcatg gcctaaatga agatcgcccg tcggattcgc agatacgaat
     8881 tccacttgga tgcgctcgcc gtttccgata tttgtttccc cgtatgcttc tcccgcttcc
     8941 aatacagatg ggatcagctt cgttaaatat tgattatcca tatagaaatt gataaatcca
     9001 gggcctgcga tatcaagctt ttcaattgaa gcctttcctt tatcaaaaga agctacaata
     9061 tcctcagcga tttggcgcgg ggcttttttt gcgattcttg ccagctgcat cgccatgttg
     9121 gttgaataat caccatgtgt tttatctttc ggtgtctcta aaatgacatt tggaatctgg
     9181 ctttcttcag ccaatcccgc tttcagaacg gctgctttaa tttcatcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtcaa gtcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctg ctgttcgtct cccacatgca tatcataagc tatgctgata cggcctcttt
     9361 ctttgccgat gtcagactga atcgattttg tgcttgtagt cagctcaagc tcgccaaatg
     9421 acattttata tttggcaatg gtagagactc ccggcacaaa ccgctgattc attttcactg
     9481 cgcctgacct catgacaaac acttcgctct cgcttacttt cacaatcgtt ttcactttgc
     9541 ccaaatcgtg ttcttcataa taagaaagat acactttatt ttgtttcaca tgataagatc
     9601 cggaggtgcg gaactcaatg acctcttctt tcccgtcatc cgcaatcaca gattttacat
     9661 ggagcgttat cggtgtctct tgtttcatgc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc gctatttaaa gttcaactgc ttctatctta ccatcattac
     9781 tcatcagttt tgaagataaa cctcataaaa agcggttaat gaaacgaaga gcatttaaat
     9841 agaaattaat gccgttttga atgttacatt tttctgaaat ctatctaata tttttcacat
     9901 tttcttcaaa atatacatat tgaaaaggta ttttgatagt tttaagatta aattacatca
     9961 gagatatgct agaaaaatta aacaagggag gatttctatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgttcaat cggagctgct tgtttagtgg acggacctat
    10081 tccagacttt gaaatcgcag gtgcaacagg gctattcggt ttatggggat aaagcatttc
    10141 ctaaaagagg catagtaaat tactgtgcct ctttttgaaa agtattttta ctttctatct
    10201 actccttagt tatacataca tgttttctca ttatttgtat catatgtata ggagatggta
    10261 tttttgctta tagagcagat gtttccattt atcagtgaaa gtgtaagagt tcaccagctt
    10321 cctgagggcg gagtattaga aattgattat atgcgtgata atgtctcgat ctctgatttt
    10381 gaatacttgg atctcaataa aacggcttac gagctttgta tgctgatgga cgggcaaaaa
    10441 acggcagaac aaatattaga atgccaatgc gcgacgtaca atgaatctcc cgaagaccac
    10501 aaggattggt attatgaaat gctcgacatg ctgctgaaca agcaggtcat tcgtcttaca
    10561 gaccagccag aatatcggcg cattgccaca agcgggagca gcgactttcc gatgccgctg
    10621 catgcgacct ttgagctgac tcaccgctgt aatttaaaat gcgcccactg ttatttagaa
    10681 agctcgcctg aagcgctagg aacggtatct cttgaacaat tcaagaaaac agcggatatg
    10741 ctgtacgaaa aaggcgtttt aacatgtgaa ataacgggcg gagagatttt tgtccacccg
    10801 aatgccaatg aactccttga gtatgtatta aagaaattta aaaaggttgc cgtcttaaca
    10861 aacgggacgc tgatgcgaaa agaaagcctg gagattttaa gagcatataa gcaaaagatc
    10921 atcgtcggta tttcactgga cagtgtccat tctgaagtcc acgattcctt tagagggaga
    10981 aaaggctctt ttgtccaaac ctgtaaaacg ataaaattat tgagtggtca cggtattttt
    11041 gtcagagtcg ccttgtcggt tttcgagaaa aacatgtggg aaattcatga catggcccaa
    11101 aaggtgcgcg atcttggtgc caaagcgttc tcttacaact gggttgatga tttcggaagg
    11161 ggcagagata ttgtccatcc gacgaaagat gccgaacagc accgcaaatt tatggagtac
    11221 gagcaaaatg tcattgatga atttaaggat ctgattccga ttatcccgta tgagagaaaa
    11281 cgtgcggcga attgcggcgc aggctggaaa tcaatcgtga tcagcccgtt cggagaagta
    11341 cgcccgtgcg cgctcttccc gaaggaattt tcattgggaa atatctttca tgattcatat
    11401 gaaagcatct ttgattccgc tctcgtccat aaactatgga aagcgcaggc gccgcggttc
    11461 agtgagcatt gcaagaaaga caaatgccca ttcagcggct attgcggagg ctgttactta
    11521 aaaggcttaa actctaacaa atatcaccgt aaaaatatct gttcctgggc gaaaaatgaa
    11581 caattagaag atgtggtcca gcttatttag gagggaaatg ttttgtcacc aacacaaaga
    11641 aaatggctat tgtatatcct ttcattcgtg tttgtcatcg gcgcggttgt ctatttcgtc
    11701 aaaagcgatt atttgtttac tctgatctcc attgtgattg ccattatatt cggaatgaga
    11761 gcgcggaagg ctgaatctcg atgagcatgt tggatataca cgctttatct gtttggtacg
    11821 aacaagataa cgtcatctta gaaaacgttg atttacattt agaaaaaggc gccgtttacg
    11881 gactgcttgg agtaaatggc gccggcaaaa caacgctgat caatacgctg acaggcgtta
    11941 atcggaattt tagcggaagc ttcaagctgt gcggcattga agttaacgcc aaaacgccgc
    12001 tgaagacatc agatcagctg aaaaccaacc gctacttcgc ggcggattat ccattgcttt
    12061 ttacagagat cacggcgaag gaatacgttt ctttcgtcca ttctctttat caaaaagaat
    12121 ttcacgaaca acaatatgtc agtttagcag aggagtttca cttttctcag tacacgaatc
    12181 ggagaatctc agagctgtct ctcggcaaca ggcaaaaggt tgttctgatg acagggttat
    12241 tgctgcgggc tcccctgttt attttagatg agccgcttgt cggcttggac gtggaatcga
    12301 ttgaagtctt ttatgagaaa atgcaggagt attgcaaggc aggtggaacc attttgtttt
    12361 cttcccatct gcttgatgtg gtgaaaagat tttgccatta tgcagctatt cttcatgata
    12421 aacagattcg caaattgatt cctattaagg atgacacaga tctgcgccgg gaatttttcg
    12481 aggtgatcgg ccatgaataa tgtgtttcaa attctttccc tgctgttcaa acagctttac
    12541 ggccggcaag ggaaaaagga tgccattcgc atcaccgccg gacttgctgt tctggctttg
    12601 tttgaaatcg gactgatccg gcaggccggc attgatgagt cggttttagg aaaaacatat
    12661 gtcacactcg cgcttctttt tatgaatgtg tatatggtat ttatttccgt ttcttcacaa
    12721 tggaaggaat cctacatgaa gctgagctgt cttttgccaa tctcttcacg tagcttctgg
    12781 cttgctcaaa gcgtggtttt gtttgtggat acttgtttga gaagaacgtt attcttcttt
    12841 attttaccat tgtttttatt tggaaccggc acgctttcag ggacggaaac gttattttgg
    12901 atcggcaaat tttcgttttt cacagtctac tccattttat taggcgttct attaagcaac
    12961 ctttttgtca aaaagaaggg atttgtgttc ctgctgcatg cggcggcatt tgcctgtatc
    13021 tgcgccagcg tggtttttat gcccgctgtg acgatcccat tatgcggggt tcacatggca
    13081 tggggcgttt tctttgattt cccctccttt ctgcaggtgc ctcatcagca gaacaagatg
    13141 cattcattca tgcggacatc ggaattttcc ttttataaga gagaatggaa tcggtttatt
    13201 tcgtcaaagg caatgttatt aaactacatt gtcatggcgg ctttcagcgg ttttttttcg
    13261 tttcagatga tgaaaaccgg catcgctgat cagcatatca tttatattgt gattaccgcc
    13321 ttgctgttaa tttgttctcc tatcgcttta ttgtattctc ttgaaaaaaa cgaccggatg
    13381 ctgttaatca cgcttccgat taaacggaga acgatgtttt gggcaaaata tcgcttttat
    13441 tccggtttgt tggcaggcgg gtttattttg atcgctatga tcgtcggttt gatcagcagc
    13501 cagccgattt cagtcatgac ttttttgcag tgtatcgaat tgctgctgat gggagccttt
    13561 attcggttaa catctgatga aaaaagaccc tctttcgggt ggcagacgga acagcagctc
    13621 tggagcggct tctcaaaata ccgctcctac gtattttgta ttcccctatt cttagcaact
    13681 atcgctggca ctgttatctc cttggcgatc atcccgattg ccgggctgat cattgtctat
    13741 ttgctgcaaa aacaggaagg tggtttcttt gatacaagga gaaaaagtga acgatttgga
    13801 aatgaacctg ttaacgactg atcaattttc aacaatctcc atcgccgcga gctttctgaa
    13861 accgatcgaa aacgcggcag agcctgaaga agaaacaatc tatttttacg gtgcggcggc
    13921 ctatctaaaa caaaacatca ctgacatctt tggatatgct gccggcagcc gctttatcta
    13981 ctcagcgaat ctattttttg accggcagct caagacatac ggaacccgct tgattcatcc
    14041 gctatatcac aaaaatctca acattgatga tgtgctggaa gcatttgttg atagatcctc
    14101 tcttccggca tctcttccgg ccgatatcgc agaaacagct aaggctgacc ttttactgaa
    14161 gatcgaaaag aagttcgccg atcctttctc ttactcggca gcccgtctgg cagaggaaac
    14221 gttcggcagt ccgatgtacg gcacagctat gtttggccgg aaagaaaagg ttcaagcgat
    14281 acagcctaaa cgctttctgg atgcatcaga ttttaaaact gatttgttgt cccagcaaaa
    14341 acagctttat gtaataggaa acgttcaaga gttacatgcc ggaggatatt ccagacacgc
    14401 accttccatg aacggtagaa gaaaacccgt caataaaaac atttatgaaa cagagacacg
    14461 cagcaccgca ggtccttccg tgatgaccct tgggtttgat tgcggagaaa tgaacggttt
    14521 ccgtgattat ataaaaatcc agctgataga cggattgctc ggaaagtacg gccattccgc
    14581 attatttcgg cattttcgcg agaaacaaat ggcggtttac catgtcatta cccgctatga
    14641 catcatgagc aatctgctgc ttgtatccgt atgtaccaat cgtgttcaag agaaagagat
    14701 tccgccaaga gtgatcgaaa cggtcatgaa ttttcatgta gatgaacagg aattagaaaa
    14761 agcgaagcaa ttcctgaaaa atgaaatcct tctgcaatta gattctccgg aaggactctt
    14821 agcctatatg ggaattctgc gtcattactc atacaaaaaa gaagacattc tagacggtat
    14881 ttcaacgatt acctgccgcg atttattaca atacgtgacc aatattgaat atattggagc
    14941 acatgtagta aggggatgag gagattggag aaagaaacct tttttcatca gcttgatgca
    15001 cgtaccgaga tcacgtacgc agacaatgga ctaaaaatat gcagagtaaa attccccaac
    15061 gcccatatga ggctgtgtaa tgtcaaagtc gatttcggca gccgggacat ccgtttgcat
    15121 tccggagaca gcgaaaaagt gctgccgtac ggcactgcgc actttttgga gcatgttctc
    15181 ttctggcata acgggcgaaa tctatacagc gatttttttg atcatggagc gcttttgaat
    15241 gcgttcacca catatacaga tacaaatttc atgtttacct ctcttcctga tcggctggag
    15301 cacacgatcc cgaaactgct tgatgcttta tggaatccct cctttgacga gaatattgtc
    15361 gctcaagaaa aaagcttgat taaaagcgaa attgaagcag ctcatctcaa tcagcagctt
    15421 cattatcatt atcagatgct gaatttgctt tctcccgcat cacccgctgc gatttttccc
    15481 gcgggcagaa cggaggatat cgaggcttta acgatcaatg atctaaaaga agcctatgca
    15541 acaggctacc agcctcagcg tatgacgatg tttctgatcg gcggctctga agatacagaa
    15601 actattttgc cttctcatct ccggctgcgc ggccgctccg gccataccgc caagagaaaa
    15661 ttcatgcctg catgccctcc tctcttacaa aatcagagcc tgggtgatgc ggagtgttcg
    15721 ggggaaacat ggaccggatt acatataggc gtactccccg ataaaaacga tctttttaca
    15781 ttgcaaatgt attgggacat cgtctcccgc gttctttttc atatagattc gccgttgttt
    15841 caagaaatcc ggcaaacgcg cctccttaat atccaaagct tatcagcgga aagtcacgtg
    15901 tcagaagatg gcggcttttt gatccttcac agtaaagggg cacattcttc agcctatatc
    15961 gatgtagcga catactatgt gatgcagcag aagtgtcagg cggaagcttg gctggagtac
    16021 ggcaaggaat ctttgctgaa cgcgatcatc tacgacagtg attatgtgcg taaatgcttt
    16081 gaatgggcgg ctgaatgtga gcggtatgat tgctcttttt tcgagcttta ccggctgatt
    16141 caaaacatga ctgtacagga ttttttatat cttattgata cagtggcttc tgctaaaaaa
    16201 gcaaccattc atgtctctca tccagaggtg gttggacaat gaaaaaaagc actgtcttca
    16261 ctgtgttatt gctgcttatg gtcatggcgg cccattcatt tggctggttt caagccagcg
    16321 ctgaagccgc ggggcaatat gtacagctga tcaaaaatga ttatgtgcgg ctcggcttgc
    16381 tttcttgtgc cgcttctgtg ctgatgctgc cggcattttt gtatcttcac tatgtcaccc
    16441 gatccgtcaa aagcatgaca gcagcttttc agaagataac gcaatctcat caaagctgct
    16501 gtgattttca gcatcgcaag ctgtgcagcc gttatgccgg cgatgtgaaa tcattgcgcg
    16561 aaagctacaa gggcatccgc caaacgtacg tgatgggggc tgtattatgc caagtgatcg
    16621 tgttcggtta catgtttgaa gtggtcaagt ccattccatt cagcttcaac gcgccccccg
    16681 ctgtcacgaa ggggcttgcg attgttctca ccatctattt attgttttat atgaggtcat
    16741 acctgctcca gcttctccag aatggacaaa cggctaaaaa ggctgtcgtt ctgttattag
    16801 caggagccgg gatatggtgg atgctcagct ttaccatgag cgaactgctg tttctgatta
    16861 tcttggctgt catccagcag gtaggttcat ttatttataa acgagtctct tatcgcagct
    16921 ccgcttctct cgacctgtga aagcatctat atcgaaatcg cagacgggcc agcgccaacc
    16981 ggaatgaccg ctacggctgt ataatcactc gtgcgatata ccgtcactgt attggctgca
    17041 ggctgcgcaa catagatata ttgattgtcc ggtgttactg tgaggtcaat ggcaccgggg
    17101 agagaggcag ttgttataaa ggtatgcagc gttgtatcaa cgacagtcaa attctccgga
    17161 aatgaatcat aatatggctc aaggaaaaat gcacgagtcc cgtcagcaga aaaaacaatt
    17221 gttattaaac cgtcaaacag tctgttaatt tgtgaagatt cgctaaatgt tgtcaaatct
    17281 atcacagaaa cgacattcgg ccttagctca ccattttcca gataagcaaa atcccctatt
    17341 aacggggttt caataagatt tggtgtttca aagttactta aactatcaat cagctgccct
    17401 gtatttatgt catatttatt aacgacccaa aatacagagt tggtcgtata gaaaaactgt
    17461 ccgttagggt ctagggcaaa atcgtccgca gcgggtgaca ccgtgaatgt attggtaatg
    17521 gtttgcgagg aaatattaat ttcataaatg gagctgcccc ctgcgagaat ataagcaaat
    17581 cctcccccag tttcaaactg gatttttctt ggggctcctg caagagggat ggtttgtgta
    17641 accgttaatg tttcgttgtt aatgatcgat acaagattcg cattcctatg gagaacatac
    17701 gtatacgctt tatccaaggt aacacccaga tcagtcggga tatcagataa agaaatggta
    17761 cttacaagag tattcacgtc agtatcaatg accgaaaccg tgctgtctcc agtgtttgca
    17821 gtaaacacgt aagatcgctg atccggcgcc ggtacaagta caatcgtccc cgtcaccgat
    17881 aaaggactgc cgtagaacgg cggaacgaca acaaggttct cgatcgtgat gtcactgaaa
    17941 tccgggcaat catccgggtt atcagaataa tagacgactt gatcgatctc tgcattgtga
    18001 atgacagaaa cagccccgtc cccttgtcca tattgatttc ttacaggtga gacactgaca
    18061 agaagcgtaa cggtcccttg cagacgcaca gcatattgaa caccgatatc ttctggttcc
    18121 ggcccagtct ggattaagca aggctcactg atacaggaca aattgtctgt actccacgta
    18181 accgctgcag ctgcttcggc agaatcaata gtgaacccct caggaatgtc aatcggcact
    18241 tgaaacagcg cttctcggct gatctcctca tcacaaaagc agaaacaatt ttcctgaaaa
    18301 gcagaaagat catttttttt cataatgtca cgtcctttta aaaatgcaca acatgcattt
    18361 ggttaaatcg caatgtcact cggtgaaacg ccaagcgata tgacagtttc cacagaataa
    18421 tcatccgtgt tgtaaacagt gatgctttgc tctataaaat gagttgcata tagaaattcg
    18481 ccattcgggg taaacgcaaa gtctcttgcc gattgcggaa gatttcctat tatgcctgca
    18541 ccacttggac tgacggaata tagattgtga gtgaaaccat caaacaaata cacccctgat
    18601 ccgctcttaa acattagata ttcaccctca tactccagct cttgggtgct actgatcgta
    18661 aacgtatcta aatcaataat cgtcaaataa ttgaagaagt gatcttcttc taatacatag
    18721 gcataccgct ccggcggctt tgtttctatg gaatttacaa taagctcccg ttcaatcgtt
    18781 cctgtaactt caccggtaga taagtccact ttttgcacta aaccaaaatc aagaacatag
    18841 gcgaacattc cattgggatc aattgcaata tcataccctt caacaggaat agacctttct
    18901 acggcagacg tttcaattct gatcacataa atggcattac cggcgagaac atatgcgaaa
    18961 tcatgttcag gcataaattt aattgtttca ggcggctgat ctagcggaat ggatgcagta
    19021 acagtcaatg tgccattatc gatgacagaa atgacactat tgttcaaatg caaaacaaac
    19081 gtagaggctt tatctggcgt aatttctata cctgttggct cgtatgggag agaaatggtt
    19141 gttataacgg tatgagtatt cgtatcaatt acggaaaccg actgatcatc tggattcgct
    19201 gtaaatgcat aaacaggctc cggctctggt tccggggcga gcacaatcgt tcctgtcacc
    19261 gataaaggac tgccgtaaaa cggcgggacg acaacaagat tttcgatcgt gatgtcactt
    19321 aaatccgggc aatcatccgg ttcatcagag taatagacga cttgatcaat ctctacattg
    19381 tgaatgacag aaacagctcc ctccccttgt ccatattggt ttcgcacagg tgagacactg
    19441 acaagaagcg tgaccgttcc ctgcaggcgg actgcaaaat ggatttcgat ctcatcaggc
    19501 ccgggtccag tctgaatgaa gcagcgttca ctgacacagg ataggctgtc tgcgttccat
    19561 gtgacattcg ctaccgcttc agcaggatca acaacaaacc cctcaggcac ttctatcggc
    19621 gcttgaaaca tggcttcacg gctggcttct tcctcacaaa aacacaaaca atcctcttgc
    19681 tgtctgacgg ctttttcttt aaaagaacgc tcaatcttat tcacatgctc acttccttct
    19741 cagaaatagc tgctaagcgc agcagtaata gagtatgggg acaaaaaggt tttgcttgta
    19801 caaaagttct aagccaaaag tgttttttta aactgaaaac gggtaaaaag aaaaagagtt
    19861 atttacaaat tatgttttat agcaggaatg tcaggttata taaaataaaa aagacttcat
    19921 aaggaggatt tatttataca agcagcctta ttacactact tatataagtt cccaagcttc
    19981 tctgggtaaa taaaaggagg atcataatga aaaggaatac aaccttgacc ggaatcgttt
    20041 ctttgctatt actattaatg ctgtctgcat gcggcagcga taatcaagac aaaaaatcag
    20101 atcaaacgat gaatatggac gacacacata ctcattctga atccagtgag attccggaag
    20161 gcctgacagc agcacagcac ccaacttata aagttggaag ccaagccatc atcaaggcgg
    20221 atcacatgaa aggcatgaag ggtgccgaag caaccattac aggagcctat gatacgacgg
    20281 cctatgctgt ttcctataca ccgacaaccg gcggaacaag agtggaaaat cataaatggg
    20341 tgattcaaga agaaataaaa aatgccagtg atgaaacatt aaaacccgga acggacgtga
    20401 ttatagaagc agatcatatg aagggaatga agggtgcaac agggaaaatc gattcagctg
    20461 agaaaacgac tgtctatacg gttgattaca ccccgacaac gggcggagaa aaagtgaaaa
    20521 atcacaagtg ggtaacagaa agtgaactat cttcaaaata aaggcagaat gtgatgatga
    20581 actgttaaac aaattggccc tatccaatat gtttaacagt ttatttttat tgtgctttga
    20641 tatggccggg agagagagag cgtttccact attcggtcac gcaaaaaaat ttgcggtttt
    20701 tttgcgcttc caaacaaaac aaaaatgata aaatatgaca tatatagaat gatgaaggga
    20761 ggggttttca aacgtgacag gcgtcatatc ttcttccatt ggagaaaaga ttaatgaatg
    20821 gtacatgtac atacgccgat tcagcatacc ggatgcggaa tatttacgaa gagaaatcaa
    20881 acacgagctg gatcaaatag aagaagacca ggatatttat ttgtattatt cactgatgga
    20941 attccggcac aatctgatgc ttgagtatct agaaccgtta gaaaaaatgc ggatagagga
    21001 acagccgcga ctgtccgatt tgctgcttga aatcgataaa aaacaggctc gtttaaccgg
    21061 agtccttgat tattacttta atctcttcag gggcatgtac gaactggacc agagggagta
    21121 cttgtctgct attaaatttt tcaaaaaagc cgaaagcaag ctgatttttg taaaggatcg
    21181 aatagaaaaa gctgagtttt tctttaaaat gtctgaatct tattactata tgaaacaaac
    21241 gtatttttcc atggactatg cacggcaggc atatgaaata tacaaagagc acacggcata
    21301 taatattaga ttgcttcaat gccattcttt gtttgctacc aatttcttag atttcaagca
    21361 atatgaggac gccatatcac atttcaaaaa agcttataca atggcagaat ccgaaaaaca
    21421 gcctcaatta atgggaagaa cgctgtataa cattgggctt tgcaaaaaca gccaagacca
    21481 gtatgagtca gcaatcacat atttcaaaag agccatatct gtttttgaag aagctaatat
    21541 tcttccttct ctgcctcaag cttatttttt gattacacaa attcattata aattaggaaa
    21601 aatggataaa
//
