LOCUS       NZ_KB913032            23493 bp    DNA     linear   CON 28-APR-2024
DEFINITION  Amycolatopsis alba DSM 44262 scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_KB913032
VERSION     NZ_KB913032.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Amycolatopsis alba DSM 44262
  ORGANISM  Amycolatopsis alba DSM 44262
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 9811274)
  AUTHORS   Klenk,H.-P., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Amycolatopsis alba DSM 44262
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: India
            num_replicons                     :: Missing
            ref_biomaterial                   :: DSM 44262
            biotic_relationship               :: Free living
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.05; ALLPATHS v. r41043; Phrap v. 4.24
            finishing_strategy                :: Missing
            environment                       :: Soil
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi10729
            Current Finishing Status          :: Level 2: High-Quality Draft
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2011
            Isolation Site                    :: Soil
            Cell Shape                        :: Filament-shaped
            Motility                          :: Nonmotile
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Gram Staining                     :: Gram+
            Diseases                          :: None
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.05; ALLPATHS v. r41043; Phrap v.
            4.24
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina GAii
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000384215.1-RS_2024_04_28
            Annotation Date                   :: 04/28/2024 01:36:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,988
            CDSs (total)                      :: 8,922
            Genes (coding)                    :: 8,855
            CDSs (with protein)               :: 8,855
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 24 of 67
            Pseudo Genes (incomplete)         :: 49 of 67
            Pseudo Genes (internal stop)      :: 4 of 67
            Pseudo Genes (multiple problems)  :: 10 of 67
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:42:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9496731
            Orig. end                         :: 9520224
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB913032.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 404842
            Source DNA and Organism available from Hans-Peter  Klenk
            (hpk@dsmz.de)
            Source DNA available from Hans-Peter  Klenk (hpk@dsmz.de)
            Organism available from Hans-Peter  Klenk (hpk@dsmz.de)
            Contacts: Hans-Peter  Klenk (hpk@dsmz.de)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23493
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="47"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23493
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23493
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13493](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13493
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(330..998)
                     /locus_tag="AMYAL_RS0143800"
     CDS             complement(330..998)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156546.1"
                     /locus_tag="AMYAL_RS0143800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_026467954.1"
                     /transl_table=11
                     /translation="MTARLVNLVFDSALPRDLAGFWEGLFSWDAPFEPAFRSEPGAKQG
                     KNRLHLDLASRSPEHQAELVDRALSLGARHTDVGQGPPEEKRVPWVVLADPEGNEFCVL
                     EPREQYAGTGAIASVVIDALDPERLARFWSAALGWEIGLREATIVGLRPPDGRGPWVEF
                     LATSEEKRRRNRLRFEIAPRRGGSRAAEVRRLRALGATGQNAEAMADPEGNEFGVLTPR
                     "
     misc_feature    1094..1107
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.94"
                     /tool="antismash"
     gene            complement(1235..1999)
                     /locus_tag="AMYAL_RS0143805"
     CDS             complement(1235..1999)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637653.1"
                     /locus_tag="AMYAL_RS0143805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_020637653.1"
                     /transl_table=11
                     /translation="MAGQAMIDQSRFLEVIGAETELMAQVAHTASADAPVPTCPGWTLG
                     EVLRHVGSVYRVTRRWITDGRRPEHWQRKPGPQQTLEEYFREGRDELVAELSAHDPDEL
                     APTWWPADRSYGFWRRRMAHEATIHRIDAENAAGREVSEIPEDVALDGIDEALVLWFGQ
                     RLPLLGLSGTKTGSVGVRTAGHTWIARAGPTETVAWRCSAEEAQRADDLITGQPDKIYR
                     WLWGRAGPTAVTVSGDQDMAGQLWALLRLATR"
     gene            complement(2024..2506)
                     /locus_tag="AMYAL_RS0143810"
     CDS             complement(2024..2506)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156540.1"
                     /locus_tag="AMYAL_RS0143810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_020637654.1"
                     /transl_table=11
                     /translation="MSVSVVSPDEAERPGGTAQPALPMSLRPPAPPAAVSLYAQARRGL
                     AEAEREDDPAERFIGAYLAALRGAAAVLEARGRPHRGRARPASGWVLLDSVAPELKEWA
                     AFFAANSATRAAAQAGITGKVTVEMADELVRAATVFLELVRRVVHGLPMGDSAYVA"
     misc_feature    2607..2622
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: strong, score: 28.4"
                     /tool="antismash"
     misc_feature    complement(2608..2621)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 22.19"
                     /tool="antismash"
     misc_feature    2608..2621
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.17"
                     /tool="antismash"
     misc_feature    2619..2632
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.17"
                     /tool="antismash"
     gene            2728..3258
                     /locus_tag="AMYAL_RS0143815"
     CDS             2728..3258
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156538.1"
                     /locus_tag="AMYAL_RS0143815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_020637655.1"
                     /transl_table=11
                     /translation="MSTIDQSGHPSVAKVATALAEAGQQAAADGIRILPAEVRTAVQAA
                     EALGVEVGAIANSLVFRSRTGDTDTALLVLTSGAHRADTGLLASLTGADKIGKADADFV
                     RAHTGQPIGGVAPVGHPKALTTLVDTALRAHDVVWAAAGHPKSVYPTTFDGLVALTGGT
                     PADVAGDGQDGRP"
     misc_feature    3121..3123
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3255..3818
                     /locus_tag="AMYAL_RS0143820"
     CDS             3255..3818
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332697.1"
                     /locus_tag="AMYAL_RS0143820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_020637656.1"
                     /transl_table=11
                     /translation="MTAMSSECTRYVQLSADEFRARLPEALTIYVDAMRYPEGTAEQRA
                     PMWLTHALREGWRCMAALDADGVLLGLAYGYKGRGGQWWHEQVRHGLTRRDGQAAAEHW
                     MSDYFELTEIHVSPGSQGKRIGEDLLRRLLDGVPSAHVLLSTPEGTSRAWNLYRRVGFV
                     DVLRDYHFAGDPRAFAILGRTLPL"
     gene            complement(3815..4696)
                     /locus_tag="AMYAL_RS0143825"
     CDS             complement(3815..4696)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637657.1"
                     /locus_tag="AMYAL_RS0143825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EamA family transporter"
                     /protein_id="WP_020637657.1"
                     /transl_table=11
                     /translation="MSVAVPTRARSSAALVLAGVLWGTGGLAGSLLASRAGLHPLSVAA
                     YRLLIGGVIATGYLWLTGGLRGLPRTSEVRRRLLTVGGLFALFQTSYFAAVSLSSVSVA
                     TMTTIGSAPVLLAVATAAKTRRLPGARTAVSLAGSLVGLALLQGTPGEKVNVAGVFFAL
                     LAAAGFAALTLVTANRVEGLDPLPTTAFGCLIGGAALIPAAWWFGMAVPLQADVLALVL
                     YFGVVPTALAYAAYFRGLEGAHPVLAALSALLEPLTAALLSTVVLGERLGAVGWCGAAV
                     LIAALAVAYSKP"
     gene            complement(4941..6626)
                     /locus_tag="AMYAL_RS0143835"
     CDS             complement(4941..6626)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075033.1"
                     /locus_tag="AMYAL_RS0143835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_039794998.1"
                     /transl_table=11
                     /translation="MASTAQSVHQICDRYVDEIAAADPVEATILGVAGYDDQLTDFSPA
                     GHAARAAIAARALADIEAAEPADDAERAAKAVFAERIGLVLEIHEAGLDLSSLNVIESP
                     AQNLRMVFDLMPAETESDWATIAVRMAKLPEALGQLRAGLLAGADAGHVSALRQVRKVA
                     EQAETWAGLKEDTGYFTTLVSGAKDVSDSLRTELGHAATIAQEAYAEFAGFLRAELAPL
                     APVKDAVGAEVYKLWSRMFTGATLDLDEAYAWGWAEFTRIETEMREVAGRIKPGATLAE
                     AAAVLDADPKYVVRGRAEFQAWMQNLSDNALKLLRGKHFDISDRVMELECKIAPPGGTV
                     GAYYTGPNEDFSRPGRMWWSLPQGRDEFTTWREVSTVYHEGAPGHHLQIATAVDQSGSL
                     NKYQRMLAFTSGHAEGWALYSERLMEDLGFLSDDGELLGMLSEQLFRAARVIVDIGMHL
                     ELEIPAGTGFHEGERWTPELGLEFMLTRTVTDPAHVHDEIDRYLGWPGQAPSYKLGERL
                     WLTARDEVRARQGDAFDIKQFHTRALALGGMGLDTLREMLASLD"
     gene            complement(6669..7553)
                     /gene="metF"
                     /locus_tag="AMYAL_RS0143840"
     CDS             complement(6669..7553)
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332694.1"
                     /locus_tag="AMYAL_RS0143840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_026467955.1"
                     /transl_table=11
                     /translation="MTSVVERLQGDGPVFSIEFFPPRDTADEAVLWKSIRELEPLDPAY
                     MSITYGAGGSSRDGTIRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNI
                     LALRGDPPGDVYGDWVPHPNGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADT
                     EYLVRKLRAGADFAIAQLFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTLRTLHTSIK
                     LSGAPAPRRLLDRLEPLADDPKAFRAAGIDAVTELCERLIAEGVPDLHFYTFNRSKATR
                     EVVSRLGLVPARA"
     gene            7691..8368
                     /gene="merB"
                     /locus_tag="AMYAL_RS0143845"
     CDS             7691..8368
                     /EC_number="4.99.1.2"
                     /GO_function="GO:0018836 - alkylmercury lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0046413 - organomercury catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="merB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156527.1"
                     /locus_tag="AMYAL_RS0143845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="organomercurial lyase"
                     /protein_id="WP_020637661.1"
                     /transl_table=11
                     /translation="MSAENDTSWDEDVRVAVYRAFAEHGRPPTAPELADAAHGSLAVAK
                     QALHRLAEQRHLVLDDCEHVVMAHPFAAIPLGFSVMGERTLWWGGCAWDAFAIPHLVKA
                     EPEVLVSTRCRGCGEPQALMVNDQAPPKSGLVAHFLVPAARMWDDVVHTCGNQRLFCGE
                     SCVDEWLTETGQDKGYVMDLATLWRLAAGWYDGRLEHGYTRRDPAAAAAYFTQAGLSGP
                     FWS"
     gene            complement(8365..8670)
                     /locus_tag="AMYAL_RS0143850"
     CDS             complement(8365..8670)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637662.1"
                     /locus_tag="AMYAL_RS0143850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AzlD domain-containing protein"
                     /protein_id="WP_020637662.1"
                     /transl_table=11
                     /translation="MTLWLAIVLVALVSIGFKAVGPVLLGDREMPPRVAGVIALLAPAL
                     LAGLVLTEVTGPAWSGVDWTLCAGLAAIAVTYVLRVPVLAAILCGVVVTALLRFLV"
     gene            complement(8667..9335)
                     /locus_tag="AMYAL_RS0143855"
     CDS             complement(8667..9335)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029308.1"
                     /locus_tag="AMYAL_RS0143855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AzlC family ABC transporter permease"
                     /protein_id="WP_020637663.1"
                     /transl_table=11
                     /translation="MTTLRRHYLAGARVGLGLGVATFVLGVTFGAYSQTLGWGIAAPIV
                     ASIVVFSGSAQFAMATALAGGGNLAVAVGAAALINARFLPMGAAVAADLRGGRLRRAWE
                     GQAVVDGSWVAAHLGEGRFDREKLIGCTLVQLPAWVLGTVLGVLAAPPPDVVARFGLDV
                     VFPGFFLVLLIDELRRSRQAVRTAALAACLAGVLVLFVPVGLALIGASAAALLGLGVRR
                     "
     misc_feature    9355..9368
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.13"
                     /tool="antismash"
     gene            9384..9932
                     /locus_tag="AMYAL_RS0143860"
     CDS             9384..9932
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332690.1"
                     /locus_tag="AMYAL_RS0143860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_020637664.1"
                     /transl_table=11
                     /translation="MDGHWDGYDSIGGSVPLDLVNTVSWRRDPVRRDDRLSSPERLSEW
                     VVLVGAGTERIEISEAVLEAVKSFRETLYRVLVSAPPDVTPLRKPLLSAYRHAELAPSF
                     PLRWTVPLSDGAALPHFLALAAEDLLRSGDLERIRECEGPGCGWIFTDHTRNRSRRWCS
                     SSDCGNRARAKRHYDKGRG"
     gene            10001..11092
                     /locus_tag="AMYAL_RS0143865"
     CDS             10001..11092
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332689.1"
                     /locus_tag="AMYAL_RS0143865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_020637665.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.1e-46, bitscore:
                     156.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTSAYDADLPAHVERALAGFLERAGAEIRRTEPTVGVGIDALAG
                     FVLGGGKRLRPTFAWWGWRGAGGDPSGPDVEGVLQAVASLELIQACALIHDDLIDSSDS
                     RRGSPTVHIAGAKLHADSGWLGSPSTFGLATAVLVGDLALAWADDMFGEAPLPPAALAA
                     ARPAWRAMRTEVLAGQYLDVRTQATGDASPEAALHICKLKTAAYTVMRPLHLGAALGGA
                     DDALIATLREFGDEVGVAFQLRDDLLGVFGDPSVTGKPAGDDLREGKRTLLVALGLQRA
                     AEQGKNAASKVISDAIGDAHLSEDAVETVREALQDVGAVDAVERRIDELTESAMAALDR
                     AHLAEPAPAALTGLVVKATQRTY"
     gene            11092..12567
                     /gene="crtI"
                     /locus_tag="AMYAL_RS0143870"
     CDS             11092..12567
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637666.1"
                     /locus_tag="AMYAL_RS0143870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_020637666.1"
                     /sec_met_domain="DAO (E-value: 7.2e-17, bitscore: 61.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVTGPSDHVVVIGGGLAGLSATLHLLGAGRRVTLLEQDKTPGG
                     RAGQADFGGNTVDTGASVLTMPELLDEAFSAVGESLADNLTLTRLDPAYRARFADGSTI
                     AVHTEAAAMEAEIRAAAGPAEAEGYRRLRRWLTELYAVQKDQFIGANFDSPFDLVRPEL
                     AKLAALGGFGRLGPKIGGFLHDDRVRRLFSFQALYAGLDPARAIGAYGVISYMDTVGGV
                     YYPSGGMGEIARSMANAAERAGAEVRFGTEAAWLERVSSRVRAVRTRSGERIPCDTVVL
                     ATELGTAYRLLGARPRRPLPLRYSPSAVVLHGHAPKSWPELGHHTIFFGQAWEKTFSEI
                     IHEGRLMSDPSLLVTRPTATEPGLAPGGDQVISVLAPAPNLRRGKIDWGRVGPAYRTEL
                     LRTLENRGLAGFAGGFTVDETITPAGWAERGLTAGTPFSLAHTFAQTGPFRPGNLVRAA
                     DNVVLAGCGTTPGVGIPPVVISGRLAAGRVTGR"
     gene            12564..13493
                     /locus_tag="AMYAL_RS0143875"
     CDS             12564..13493
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156497.1"
                     /locus_tag="AMYAL_RS0143875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_020637667.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.4e-112,
                     bitscore: 372.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.3e-59,
                     bitscore: 200.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSELDAAGITAPALRAAYTECRRINAHHGRTFFLATRLLPARTRP
                     FAHALYGFARMADEVVDNPAPGTDPAVALDDVAVMVGQVFDGGTPADPVLAALADTVRR
                     HDLDRELFDAFLWSMAMDLKVTEYATYADLKEYIHGSAEVIGLQMLPVFGTVVPVEEAM
                     PGAAALGEAFQLTNFLRDVGEDLDRGRLYLPTGELAAFGVDRELLEWSRARGLPDRRVR
                     RALAVAVARNRAVYRRAEAGIPLLRPESRDCVRTALTLYEGILDEIAALGYDVLNTRAV
                     VPRRRRAAVALPRLLASTWSNSRLKVRS"
     gene            13490..14275
                     /locus_tag="AMYAL_RS0143880"
     CDS             13490..14275
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637668.1"
                     /locus_tag="AMYAL_RS0143880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_020637668.1"
                     /transl_table=11
                     /translation="MTSASNRKIRIGVQLQPQHAEYKAIRRAASEAEDLGVDIVFNWDH
                     FYPLYGEPEGLHYECWTMLGAWAESTSRVEIGALVTCNSYRNPELLADMARTVDNISDG
                     RLILGIGSGWFEKDYDEYGYEFGTAGGRLDNLAEALPRIESRLGKLNPQPVRDIPVLIG
                     GGGEKKTLRLVAKHADIWHGFGDPEVVERKVKILDQHCADVGRDPKEIERSVAVEGEPE
                     ELGPKLLEHGVSLFTVATGGPDYNLDKLRSWIAWRDKQG"
     gene            complement(14411..14962)
                     /locus_tag="AMYAL_RS0143885"
     CDS             complement(14411..14962)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156491.1"
                     /locus_tag="AMYAL_RS0143885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_020637669.1"
                     /transl_table=11
                     /translation="MTSAQQDFLPGRSARAGAQRAVDLLAVLLVPEPSVSAVRSVLEAH
                     GETSVELGPSDVASLREAASELREVFAARDAAEAAGVLNRLLARYAHAPRLTDHDAGFG
                     WHLHVDAADDGPWGAWLVTSSALVLAVLLADRQAPPGGLCAASGCGKPFAHLGGGSPRR
                     YCSTRCATRERVAAHRRKRS"
     gene            14985..16163
                     /locus_tag="AMYAL_RS0143890"
     CDS             14985..16163
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156488.1"
                     /locus_tag="AMYAL_RS0143890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_026467956.1"
                     /transl_table=11
                     /translation="MRSRYRLAVYLTGATVARTGDELSGPALLLLGLSVDGSAATGSAL
                     LAGLTISAAAGGPLLGALLDRSPRPGRLLAWALLAYAGGLGAVLALVEVPAAIAVAVAA
                     GLLNPALAGGWTAQLPNVRGGTPLARASALDAMTFTAASLAGPGLAGLVAAYAGAPAAV
                     AVAITLVAVAFPAAWSLPAVEAKPAKPILRRLADGFAVLFRNRSLLRATATSTVSFVGI
                     GVALVCYPLLGAQRLGNPGFGALLLTVLAAASLIANAVLARKPPPPDSTVLVTTVLLGA
                     SFLLAATGDDAVTLLAAAVLAGFAEGPQLSALFAIRHREAPADVRAQVFTTAASVKITG
                     LATGAAAAGPLSALSVTAALSAAAGCQLLAAATYVLVKPSGRTRTPSPERAA"
     gene            complement(16132..16500)
                     /locus_tag="AMYAL_RS0143895"
     CDS             complement(16132..16500)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657740.1"
                     /locus_tag="AMYAL_RS0143895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_020637671.1"
                     /transl_table=11
                     /translation="MSGIPVADDVLDADVAVLPITEVATALNVSANKVRQMLRDGHLIA
                     VRRKGDLYVPAAFLVKDGVVKGLAGTITVLADSGFSRTEMLRWLFAEDDTLPGATPVNA
                     LRTSHGTEVKRRAQAMAF"
     misc_feature    16616..16627
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.47"
                     /tool="antismash"
     gene            16685..18736
                     /locus_tag="AMYAL_RS0143900"
     CDS             16685..18736
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029317.1"
                     /locus_tag="AMYAL_RS0143900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PASTA domain-containing protein"
                     /protein_id="WP_020637672.1"
                     /sec_met_domain="Pkinase (E-value: 1.1e-45, bitscore:
                     155.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTDPTLVGTLLEGRYRVDKLLARGGMSSVYRGVDTRLDRQVAI
                     KIMDPRFADDRSFVERFEREARSAARLHHPHVVAVHDQGFDTPGGEESGRAFLVMELVD
                     GGTLRELLTERGPLDVALALSIAEPVLSALAAAHAAGLVHRDVKPENVLIGRGGTALSG
                     GVVKVGDFGLVRAVASAGTTSSSVILGTVAYVSPEQVSTGATTSSGDVYSAGILLYEML
                     TGRAPYTGDTAISVAYRHVNDDVPRPSELRPDIPPMLDELILRATRRDPGQRPADASAF
                     LAELNHLRTALGVPPVPVPVPLPADADRETDAERTTPGIPAVPAASPTAATTVLTPVAE
                     ATMPVTGPRGTQAMQREPHFAAQPPRTSPPRPKPPADDEKPGSRKRLYLMIAAAVVILG
                     GLIGAFAFILNDTGPTSSSVPKLAGMNQAAAGDALRSAKLTPAYTEEYSDTAAQHTVIR
                     SDPAAGTSLAPGATVNVVLSKGRPIVPDIQAGTSQQDAETAIKAAQLTPAQGEQEYSDV
                     AKGKVIRVDPSPGSQLNIGGQVTLILSKGPEPLPPVPDVTGQAKDAAFQILQQAGFQPF
                     QAGEEFSDQFVAGQVIRTDPKGGGKASNRRIGVFVSNAVEVPNVTFKRWEEAVQILRQA
                     GLDADREGHGNGNGHGGGNGGFDFVVQQDPQPGAKVPKGTKVRLRVFG"
     gene            18867..19658
                     /locus_tag="AMYAL_RS0143905"
     CDS             18867..19658
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029318.1"
                     /locus_tag="AMYAL_RS0143905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_020637673.1"
                     /transl_table=11
                     /translation="MSFFTDSPRGRPLFPVPEQELFGYNGRPWVESPHEYIVPAILPWS
                     MPLGRAERTIVALRGIEVWPESVTFQLSVYARDLLLDEPGEGLIDHRRVPDYNALLVGV
                     LFPDGRRASSETISVPSAAKPDQPVLRAQGLGGTSFHVDHEIFLWPLPPDGPLEFIVQW
                     LDRDIEETRTPLDGTAIRDAAKEASEIWPGLPAREAHGLPFRRVGAQAMITPAWPRESQ
                     APPPLPQPKRTSPPSPPPAQATADQPRRGAPLPTRLPRRAR"
     gene            complement(19770..20603)
                     /locus_tag="AMYAL_RS0143910"
     CDS             complement(19770..20603)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637674.1"
                     /locus_tag="AMYAL_RS0143910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_020637674.1"
                     /transl_table=11
                     /translation="MTILVTGATGSVGRLLVNELVKAGAPVRALTVNPVKAALPEQVEV
                     AKGYLGKPETLPEALEGIETVYLAPLADTVDDFVKLAKEAGVRRVVALSGSNADDPVEN
                     SSGVAYAIIEKAVREAEFDWTFLRPGAFMNNTLGWAETIKAERVVRDAYAEATMTPIDL
                     ADIAAVAAHVLLTEGHVGKKHTLSGPTAISQREQVAAISAALGEKVTFQELTREEAEKQ
                     WAGAGIPAEIAEWLLDGFAYFTENPDKPTGVVQELTGRPGVTYAEWAVANVEAFR"
     gene            20699..21448
                     /locus_tag="AMYAL_RS0143915"
     CDS             20699..21448
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332679.1"
                     /locus_tag="AMYAL_RS0143915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_026467957.1"
                     /transl_table=11
                     /translation="MDFERSLELLWRDSGETRQPTRGRKPKLTLDQVIATAVALADGAG
                     EATVSMSQIAKELGAGTMTLYTYVPGKTELLDLMVDSVLAERDLPGPGAPRPDGWREQV
                     RLYAERTLAVFRAHPWLRSTSMVRPVLGPGLMAGQEYLIAAVSDIGLPPRKAAAAANSI
                     EIYVQANATLFAETAQVEQQTGQTTDAWWGQRSVFWEKYFDVKRHPAMTRLWESGGYEA
                     ETCEAADEAFTFGLERMLDGIEALVAR"
     gene            complement(21456..22292)
                     /locus_tag="AMYAL_RS0143920"
     CDS             complement(21456..22292)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332678.1"
                     /locus_tag="AMYAL_RS0143920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="WP_026467958.1"
                     /transl_table=11
                     /translation="MTQTGERRRPAEPGRRPRGERVKRTPRAERTQRLKERRGRRSVHD
                     RHRTARPARHKEMRRRWVAVLSLLTIAALVYLLWFSSMLGVRQVDVAGANSVPAEQIRA
                     TAAVPDQKPMLRVDTDEIRDRVAQMPGIATVDVSRSWPGTLEITVTERAAIAFFDSGPG
                     GDGVHLVDGAAVVFKTVKERPAGLPELKLPSVSADDPVTRAVTGVLGVIPQQLLKQVTT
                     ATAKTPGSVEFTLADGKTVRWGTSADTERKAKVLAALLTREGKVFDVSAPDLPTVS"
     misc_feature    22332..22346
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     misc_feature    22551..22565
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    23285..23300
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.97"
                     /tool="antismash"
     misc_feature    complement(23480..23493)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
ORIGIN
        1 agctgcttcg gcaggccggt ggcgggccgc aggacgatct cgtcgagcac gccgccgggg
       61 accgggagca ccgacagccc gaggatgttg cattcgaggt cggccagccg gatcgcgatc
      121 ctggccaggg tgccgggcct gtcgtcgacg cggatgcgga cccgccaggc cgacgcggcc
      181 gctgtctcgt caccgaggtg gaccggggcg ggaaggactc gataggtctc catgacctcc
      241 acggtcccgg ccggttgttg cctgccaacg gcgcgggtgt ttcgcgcagg tcagcgttcg
      301 atgccgcggc gcaacccgga cgaaacaact cagcggggcg tgagcacgcc gaactcgttg
      361 ccctccggat cagccatcgc ctcggcgttc tgccctgtcg cgcccagcgc ccgcagacgc
      421 cggacctcgg ccgcccggct gccgcctcga cgcggcgcga tctcgaaccg cagccggttc
      481 cggcgccgtt tctcctcgct cgtggcgagg aactcgaccc acggaccgcg gccgtccggc
      541 ggccgcaggc ccacgatcgt cgcttcccgg aggccgatct cccagcccag cgcggccgac
      601 cagaaccgcg cgagccgctc cgggtcgaga gcgtcgatga cgaccgacgc gatcgcaccg
      661 gtgcccgcgt actgctcgcg gggctcgagg acgcagaact cgttgccctc gggatccgcc
      721 agcaccaccc acggcacccg tttctcctcc ggcgggccct ggccgacgtc ggtgtgccgt
      781 gcgccgaggg acagcgcacg gtccaccagc tcggcctggt gttccggcga tcggctcgcc
      841 agatccaggt gcagccggtt cttgccctgt ttggcccccg gctcggagcg gaaggccggt
      901 tcgaacgggg cgtcccagct gaacagccct tcccagaaac ccgccagatc tctgggaagg
      961 gccgagtcga agaccaggtt caccagacgt gctgtcaccc cggtgaacct agacggcacc
     1021 accgacactt ttgttcgttt aggtgaaccc gcgtccgcga tcgacgtcgg cagggcgctc
     1081 gccggtcaag cacgtcacgc tgagcgagca gggcgccctg ccaccgcgat agcggggcct
     1141 tcggccgggg cgggttcacg tgttcggtca cttctctggc acatcttcag ctccgccgac
     1201 tggcgctgac cggtttggct tccccaccga ccggtcatcg ggtcgcgagc cgcaaaaggg
     1261 cccagagttg tcccgccatg tcctggtctc cgctgaccgt caccgccgtc ggacccgccc
     1321 ggccccagag ccagcggtag atcttgtccg gctgcccggt gatcagatcg tccgcgcgct
     1381 gggcctcctc ggccgagcat cgccaggcga ccgtttccgt gggccccgct ctggcgatcc
     1441 aggtgtggcc cgcggtccgc acgccgaccg atccggtctt ggtgccggac agtcccagca
     1501 acggcagccg ctggccgaac cagagcacca gcgcctcgtc gatgccgtcg agcgccacgt
     1561 cttcggggat ctccgacacc tcccgtccgg ccgcgttctc cgcgtcgatc cggtggatcg
     1621 tcgcctcgtg cgccatccgc cgccgccaga acccgtagct gcggtccgcc ggccaccagg
     1681 tcggcgccag ttcgtccgga tcgtgcgcgg acagttcggc gaccagttcg tcccggccct
     1741 cgcggaagta ctcctccagg gtctgctgcg gccccggttt gcgctgccag tgctcgggac
     1801 ggcgtccgtc ggtgatccag cggcgggtga cccggtacac gctgccgacg tgcctgagca
     1861 cttcgccgag cgtccagcct gggcaggtcg ggaccggcgc gtcggcggac gcggtatgcg
     1921 ccacctgagc catcagctcg gtttcggcgc cgatcacctc caggaatctg ctctggtcga
     1981 tcatggcctg cccggccatc gggcaccccc tctctgcggt ggctcaggcg acatacgccg
     2041 aatcacccat cggcagcccg tgcaccaccc gtcgcaccag ttccaggaac acggtggcgg
     2101 cccgcaccag ctcgtccgcc atctcgacgg tgaccttccc ggtgatgccc gcctgcgcgg
     2161 cggcccgtgt cgccgagttg gccgcgaaga acgccgccca ctccttcagt tcgggggcga
     2221 cggagtcgag cagcacccag ccgctcgccg gccgggcacg gccccggtgc ggccggccgc
     2281 gggcctccag gaccgccgcg gcgccccgca gcgcggcgag ataggccccg atgaaccgct
     2341 ccgcgggatc gtcctcccgc tctgcctcgg cgagcccccg cctcgcctgc gcgtacaagg
     2401 agaccgccgc gggtggtgcc ggcgggcgca acgacatcgg cagggcgggc tgcgcggtgc
     2461 cccccggcct ctcggcttcg tcgggggaca cgaccgaaac ggacatgacg accctcctcc
     2521 tgtacgtgag cgccggccgg tgcccggcgc cgaggcgctt cccccgcccc cgcgccgggc
     2581 acctaccggt gcgcgctcac cgaatgtcga acgtctgttc gaacgagtcc aatgtaaccc
     2641 cgaacagccc atttcttcaa ccccgtagcc gggtgatcgc cgcatgtggt gcgggacacg
     2701 ggatcggcca cgtgatctca taggctcatg agcaccatcg accagtccgg tcatccctcg
     2761 gtggcgaagg tcgcgaccgc actcgccgag gcgggccagc aggccgccgc cgacgggatc
     2821 cggatcctcc ccgccgaagt ccgcacggcc gtgcaggccg ccgaagcgct cggtgtcgag
     2881 gtcggcgcga tcgcgaacag cctcgtgttc cgcagccgca ccggcgacac ggacacggcc
     2941 ctgctcgtgt tgacttccgg cgcgcaccgg gccgacaccg ggctactggc ttcactgacc
     3001 ggcgccgaca agataggcaa ggcggacgcg gatttcgtgc gcgcgcacac cgggcagccc
     3061 atcggcggcg tcgccccggt cggtcacccg aaggcgttga ccactctcgt cgacaccgcg
     3121 ttacgcgctc acgacgtcgt ctgggccgcc gccgggcatc cgaagtcggt gtaccccacg
     3181 acgttcgacg gcctcgtcgc gctgaccggg ggcactcccg cggacgtcgc gggcgacggg
     3241 caggatgggc gcccgtgacc gcgatgtcct cggaatgcac tcgttacgtc cagctgtccg
     3301 cggacgagtt ccgcgcccgg ctccccgagg cgctgaccat ctacgtcgac gccatgcgct
     3361 accccgaggg cacggcggaa caacgcgccc cgatgtggct cacgcacgcg ctgcgcgaag
     3421 gctggcgttg catggccgcg ctcgacgcgg acggtgtcct gctcgggctc gcctacggct
     3481 acaagggccg cggcggccag tggtggcacg agcaggtccg ccacggcctg acccggcgtg
     3541 acggccaggc cgccgccgag cactggatgt ccgactactt cgagctcacc gagatccacg
     3601 tcagccccgg aagccagggg aaacggatcg gcgaggacct cctgcgacgg ctgctcgacg
     3661 gcgtgcccag cgcccacgtc ctcctttcca cgccggaagg caccagccgg gcctggaacc
     3721 tgtaccggcg cgtcggattc gtcgatgtgc tgcgggacta ccacttcgcc ggggatcccc
     3781 gcgcgttcgc gatcctcggc cggacactgc ccctctaggg tttggagtag gcgacggcga
     3841 gcgcggcgat gagcaccgcc gcgccgcacc accccacggc gccgagccgt tcccccagca
     3901 cgaccgtgga cagcagcgcg gccgtcaacg gttcgagcag ggcggacagc gccgcgagca
     3961 cgggatgcgc gccttcgaga ccgcgaaagt acgccgcgta cgccagcgcc gtgggcacga
     4021 caccgaagta gaggacgagc gcgagcacgt cggcctgcag cggcacggcc atcccgaacc
     4081 accacgcggc gggaatgagc gcggcaccgc cgatcaggca gccgaaagcc gtggtgggca
     4141 agggatccag gccctcgaca cggttcgcgg tcaccagggt cagcgcggcg aatccggccg
     4201 cggcgaggag cgcgaagaac actccggcga cgttgacctt ctcccccggt gtcccttgca
     4261 gcaacgcgag tccgacaagg gacccggcca gggacaccgc cgtccgcgct ccgggcaggc
     4321 ggcgggtttt ggcggccgtc gcgacggcga gcaggacggg cgcgctgccg atggtggtca
     4381 tggtcgcgac gctcacggaa ctcagcgaga ccgcggcgaa atagctggtc tggaagagcg
     4441 cgaacaggcc gccgaccgtc agcagacggc ggcggacctc cgaagtacgg ggaaggccgc
     4501 ggaggccgcc ggtgagccag aggtagccgg tggcgatcac gccgccgatg agcagccggt
     4561 acgcggcgac gctcagcgga tggagtcccg cgcgggaggc gagcagggat ccggcgaggc
     4621 cgccggtccc ccagaggaca ccggcgagga cgagcgcggc cgacgatcgg gcgcgcgtgg
     4681 gtacggcaac ggacatgggg aaacgctcct gcgtctgtgt cggtcggaag ggacgtcgac
     4741 gacgcggggt gcttcagtgc agcacggatc ggccgggcgg ctggaacgcc gcgcggccgg
     4801 agacaccccg ctcaggaggc ggggggtggg gtgacgagaa agatccggtg cacgagggga
     4861 acataccgcc cgaagtccgt gaaggcctcc ttgagggact ctgagtccct caaggaggcc
     4921 ttcacggaca tacgaggact tcagtccagg gacgcgagca tttcgcggag ggtgtccaag
     4981 cccatcccgc cgagcgccag ggcccgcgtg tggaactgct tgatgtcgaa ggcgtcgccc
     5041 tgccgggcac ggacctcgtc gcgtgcggtg agccagaggc gttcgccgag cttgtacgac
     5101 ggcgcctgcc ctggccagcc caggtagcgg tcgatctcgt cgtgcacgtg ggccgggtcg
     5161 gtgacggtcc tggtgagcat gaactccagg cccagttcgg gcgtccaccg ctcgccctcg
     5221 tggaaaccgg tgcccgccgg gatctccagc tccaggtgca tgccgatgtc gacgatcacg
     5281 cgcgcggcac ggaacagctg ctcggacagc atgcccagca gttcaccgtc gtcggacagg
     5341 aacccgaggt cctccatcag ccgctcggag tacagcgccc agccctcggc gtgcccggag
     5401 gtgaacgcca gcatccgctg gtacttgttg agcgagcccg actggtcgac cgcggtcgcg
     5461 atctgcaggt gatggcccgg cgcgccctcg tggtagacgg tgctgacctc gcgccaggtg
     5521 gtgaactcgt cccggccctg cggcagcgac caccacatgc ggccgggccg cgagaagtcc
     5581 tcgttcgggc cggtgtagta cgcgccgacg gtgccgccgg gcggggcgat cttgcactcc
     5641 agctccatca cccggtcgga gatgtcgaag tgcttgccgc gcagcagctt cagcgcgttg
     5701 tcggacaggt tctgcatcca ggcctggaat tccgcccggc cgcggacgac gtacttgggg
     5761 tcggcgtcga ggacggcggc cgcctcggcg agggtggcgc cgggtttgat ccggccggcg
     5821 acctcgcgca tctccgtttc gatgcgggtg aattcggccc agccccaggc gtaggcctcg
     5881 tccaggtcga gggtggcccc ggtgaacatc cgtgaccaca gcttgtacac ctcggcgccg
     5941 acggcgtcct tgaccggcgc cagcggggcg agttcggccc ggaggaaacc ggcgaactcg
     6001 gcgtacgcct cctgcgcgat ggtggcggcg tggccgagtt cggtgcgaag gctgtcgctg
     6061 acgtccttcg cccccgagac cagcgtggtg aagtacccgg tgtcctcctt gagcccggcc
     6121 caggtctccg cctgctccgc gaccttgcgg acctggcgca acgcggagac gtgacccgcg
     6181 tcggcaccgg cgagcagccc cgccctcagc tgacccagcg cctcgggaag cttcgccatc
     6241 cggacggcga tcgtcgccca gtccgactcg gtctcggcgg gcatgaggtc gaagaccatc
     6301 cgcaggttct gcgccgggct ctcgatcacg ttcagcgacg aaaggtcgag gcccgcctcg
     6361 tggatctcca gcaccagccc gatccgctcg gcgaacaccg ccttggccgc gcgctccgcg
     6421 tcgtcggcgg gttcggccgc ctcgatgtcg gcgagcgcgc gggcggcgat cgcggcccgc
     6481 gccgcgtgcc cggcgggcga gaagtcggtc agctgatcgt cgtacccggc gaccccgagg
     6541 atcgtcgcct cgacggggtc cgccgccgcg atctcgtcga cgtaccggtc acagatctgg
     6601 tgcacacttt gcgcggttga agccatgcgg cgaacgctac ccggaccgcg ggcgccttcg
     6661 gtacggagtt acgcgcgagc cgggaccagg ccgagcctgc tgaccacctc acgcgtggcc
     6721 ttggaccggt tgaacgtgta gaagtgcagg tcggggacgc cttcggcgat gagccgttcg
     6781 cacagttcgg tgaccgcgtc gattcccgcc gcgcggaagg ccttcgggtc atcggccagc
     6841 ggttcgagcc ggtccagcag ccgccgcggg gcgggcgcgc cggacagctt gatcgacgtg
     6901 tgcagcgtcc gcagcgtggt cagcggcatg atgccgggga tgaccagcgc ctcgcagccg
     6961 gtggccgcca cccggtcccg caggcggagg aagtcttccg gttcgaagaa cagctgcgcg
     7021 atcgcgaaat ccgcgcccgc gcggagcttg cgcaccaggt actcggtgtc ggcttcgagg
     7081 ttcgccgacc tcgggtggcc gtacgggaag gccgagacgc cgacgcagaa gtcgccgagg
     7141 gaacgcacca gttcgacgag ttcctcggcg tagttgagcc cgttcggatg cgggacccag
     7201 tcgccgtaga cgtcgccagg cgggtcgccc cgcagcgcga ggatgttccg cacgccgacg
     7261 gcggcgtacc agccgatgac gttgcgcagt tccgcgaccg agtggttcac cgcggtgagg
     7321 tgcgccatcg gcaccagcgt ggtttcggtg gcgacgcggg cgatgctgcg gatcgtgccg
     7381 tcccggctgg agccgccggc gccgtaggtg atcgacatgt acgccgggtc cagtggctcg
     7441 agttcccgga tcgacttcca cagcacggcc tcgtccgccg tgtcgcgagg cgggaagaac
     7501 tcgatggaga acacgggacc atcaccctgc aaccgctcga ccacggacgt cataccgctc
     7561 atgttaaggg ggaaagtccg cttgctggga gccccctctc aggctatggg cgtgccgctt
     7621 cagccgctca cgagcggttg ccgagtggcg cccgcctggg gagactcggg ggcgagcaca
     7681 aggagccgtc atgagcgccg aaaacgacac cagctgggac gaggacgtcc gcgtcgcggt
     7741 ctaccgcgcg ttcgcggagc acgggaggcc gccgacggcg ccggaactgg ccgacgccgc
     7801 ccacggatcg ctcgcggtgg cgaaacaggc gctgcaccgg ctcgcggagc agcggcacct
     7861 ggtgctcgac gactgcgagc acgtcgtgat ggctcacccg ttcgcggcga tcccgctggg
     7921 gttctccgtg atgggtgagc ggacgctgtg gtggggcggc tgcgcgtggg acgcgttcgc
     7981 gatcccgcat ctggtcaagg ccgaacccga ggtgctggtg tccacgcgct gccggggttg
     8041 cggcgaaccg caggccctga tggtgaacga ccaggccccg ccgaagagcg ggctggtcgc
     8101 gcatttcctg gtcccggcgg cgcggatgtg ggacgacgtc gtgcacacct gcggcaacca
     8161 gcggctgttc tgcggtgagt cctgtgtgga cgaatggctc acggaaacgg ggcaggacaa
     8221 gggttacgtc atggatctgg cgaccttgtg gcggctggcg gccggctggt acgacggcag
     8281 gctcgagcac ggttacaccc gccgggaccc ggccgccgcg gccgcgtact tcacccaggc
     8341 cgggctgagc ggcccgttct ggagctagac caggaaccgc agcaaggccg tgacgacgac
     8401 gccgcagagg atcgcggcga gcaccgggac gcgtagcacg taggtcaccg cgatcgcggc
     8461 cagtcccgcg cagagcgtcc agtcgacccc ggaccaggcc gggccggtca cctcggtgag
     8521 cacgagaccg gccagcagcg cgggcgcgag cagcgcgatc acgcctgcca cgcgcggcgg
     8581 catttcccgg tcgccgagca ggaccgggcc caccgccttg aacccgatac tgaccagcgc
     8641 caccaggacg atggcgagcc agagcgtcat cgccgcaccc ccaggcccag cagcgcggcg
     8701 gccgaggcac cgatcagcgc gagcccgacc gggacgaaca gcaccaggac cccggcgagg
     8761 caggcggcga gggccgcggt ccggaccgcc tggcgcgaac ggcgcagttc gtcgatgagc
     8821 aggaccagga agaagccggg gaacacgacg tcgagcccga accgcgcgac gacgtccggc
     8881 ggtggcgcgg ccagcacccc gagcaccgtg cccagcaccc atgcgggcag ctggacgagc
     8941 gtgcagccga tgagtttctc gcggtcgaag cgcccttcac cgagatgagc ggccacccac
     9001 gaaccgtcga cgacggcctg gccctcccac gcccggcgca gccgcccgcc gcgcaggtcc
     9061 gcggcgacgg cggcgcccat cggcaggaac cgggcgttga tcagggccgc ggcgccgacc
     9121 gcgacggcga ggttgccgcc gcccgcgagc gcggtggcca tcgcgaactg ggccgagccg
     9181 gagaacacga cgatcgaagc gacgatcggg gccgcgatcc cccagcccag agtctgactg
     9241 taggcgccga aggtgacgcc gaggacgaag gtcgcgacac ccagcccgag cccgacgcgg
     9301 gcgccggcca gatagtgccg ccggagcgtt gtcatgcccc cgaccctaac aagctaaact
     9361 gattttgacc attaggagga tccatggacg gccactggga cgggtacgac agcatcggcg
     9421 ggagtgtgcc gttggacctg gtcaacaccg tttcctggcg gcgtgatccg gtcaggcggg
     9481 acgaccggct ttcgagtccg gaaaggctgt ccgagtgggt cgtcctggtc ggcgcgggca
     9541 ccgaacggat cgagatctcc gaggccgtcc tggaggcggt gaagtccttc cgcgagacgc
     9601 tctaccgcgt gctcgtgtcg gctccgccgg acgtcacacc gctgcgaaag ccactgctct
     9661 cggcgtaccg gcacgccgaa ctcgcaccgt ccttcccgct gcggtggacc gtgcccttgt
     9721 ccgacggcgc cgcgctgccg cactttctcg cgctggcggc cgaggacctg cttcgctccg
     9781 gagacctcga acggatccgg gaatgcgagg ggccggggtg cggctggatc ttcaccgacc
     9841 acacgcgtaa caggtcgcgg cgctggtgca gttcgtcgga ctgcggaaac cgggcgcggg
     9901 cgaagcggca ctacgacaag ggccgtggct gacgtctgtt tcgccacatt cgaaggcacc
     9961 cgactgggtc acggcggtgt ccttcccgga ggatgtgctc atggacacgt ccgcctacga
    10021 cgccgatctg cccgcccacg tcgagcgggc gctggccggg ttcctcgagc gcgccggtgc
    10081 cgaaatccgc cgcaccgaac cgaccgtggg cgtcgggatc gacgcgctgg ccgggttcgt
    10141 gctgggcggc ggcaaacggc tgcgcccgac gttcgcctgg tggggctggc gcggcgcggg
    10201 cggcgatccg tcggggccgg acgtcgaagg cgtgctgcag gcggtggcga gcctggagct
    10261 gatccaggcg tgcgcgctga tccacgacga cctcatcgac tcttccgatt cgcgccgcgg
    10321 ttccccgacg gtgcacatcg cgggcgccaa actgcacgcc gacagcggct ggctgggttc
    10381 gccgagcacg ttcgggctcg cgaccgccgt cctggtcggc gacctcgcgc tggcctgggc
    10441 cgacgacatg ttcggcgagg ccccgctccc gcccgcggcc ctcgcggcgg cgcggcccgc
    10501 gtggcgcgcg atgcgcaccg aggtgctcgc cgggcagtac ctcgacgtcc gcacccaggc
    10561 caccggcgac gcctcccccg aggccgcgct gcacatctgc aagctcaaga cggccgcgta
    10621 caccgtgatg cgcccgctgc acctcggtgc cgcgctcggt ggcgccgacg acgccctgat
    10681 cgcgacgctg cgcgagttcg gcgacgaggt cggcgtggcg ttccagctgc gggacgacct
    10741 gctcggcgtg ttcggcgacc cgtcggtcac cggcaagccc gcgggcgacg acctgcgcga
    10801 aggcaagcgg acgctgctgg tcgcgctggg tctccagcgc gcggccgaac agggcaagaa
    10861 cgccgcgtcc aaggtcattt ccgacgccat cggcgacgcg cacctgtccg aagacgccgt
    10921 cgagaccgtt cgcgaggcac tgcaggacgt cggcgccgtc gacgcggtgg aacgccgcat
    10981 cgacgagctc accgagtccg cgatggcggc gctggaccgc gcccacctgg ccgagcccgc
    11041 tcccgccgcg ctgaccgggc tggtcgtcaa ggcgacccag cggacgtact gatgcgcacc
    11101 gtcaccggtc cgagtgacca cgtggtggtg atcggtggcg ggctcgccgg gctgtcggcg
    11161 acgctgcatc tgctcggcgc cggacgccgc gtgaccctgc tggagcagga caagactccc
    11221 ggcggccggg ccggtcaggc ggatttcggc ggcaacaccg tcgacaccgg cgccagcgtg
    11281 ctgaccatgc cggaactgct cgacgaggcg ttctcggcgg tcggcgaatc cctggcggac
    11341 aacctgacgc tgacacggct cgacccggcg taccgcgcga ggttcgccga cggcagcacg
    11401 atcgccgtgc acaccgaggc ggcggcgatg gaggccgaga tccgcgcggc cgccggtccg
    11461 gccgaagccg agggctaccg gcggctgcgg cgctggctga ccgagctgta cgcggtgcag
    11521 aaggatcagt tcatcggcgc gaacttcgac tcgccgttcg atctcgtgcg cccggaactg
    11581 gcgaaactgg ccgcgctggg cggattcggg cggctcggcc cgaagatcgg cggtttcctg
    11641 cacgacgacc gggtgcggcg cctgttctcc ttccaggcgc tctacgcggg gctcgacccg
    11701 gcacgcgcga tcggcgcgta cggcgtcatc tcctatatgg acaccgtcgg cggggtctac
    11761 tacccgtcgg gcgggatggg cgagatcgcg cggtcgatgg cgaacgccgc cgagcgcgcg
    11821 ggcgcggagg tgcgcttcgg caccgaagcc gcttggctgg aaagggtttc ctcgcgggtg
    11881 cgcgcggtac ggacccgctc gggcgagcgg atcccttgcg acaccgtggt tctcgcgacc
    11941 gaactcggaa ccgcgtaccg gctgctcgga gcacgcccgc gtcgtccgct gccgctgcgg
    12001 tactcgccgt cggccgtcgt gctgcacggg cacgcgccga aatcgtggcc ggaactgggc
    12061 caccacacca tcttcttcgg tcaggcctgg gagaagacgt tctcggagat catccacgag
    12121 ggcaggctga tgagcgatcc gtcgctgctg gtgacccggc cgaccgcgac cgaaccaggc
    12181 ctcgcccccg gcggcgacca ggtgatctcg gtgctggccc cggcaccgaa cctgcgccgc
    12241 ggcaagatcg actggggccg ggtcgggccc gcgtatcgca cggaactcct gcgcacactg
    12301 gaaaaccgcg gtctcgccgg cttcgcgggc ggcttcaccg tcgacgagac gatcaccccg
    12361 gcaggctggg cggaacgcgg gctcaccgcg ggcaccccgt tctcgctcgc gcacaccttc
    12421 gcccagaccg gcccgttccg gccggggaac ctggtgcggg cggcggacaa cgtcgtactg
    12481 gcgggctgcg ggacgacacc gggcgtcggc atcccgccgg tggtgatctc cggcaggctc
    12541 gccgcgggaa gggtcaccgg ccgatgagcg aactcgacgc cgcgggtatc accgcaccgg
    12601 cgttgcgggc cgcgtacacc gaatgccgcc gcatcaacgc gcaccacggc cgcacgttct
    12661 tcctcgcgac ccgtctgctg cctgccagga cgcggccgtt cgcgcacgcg ctgtacggct
    12721 tcgcgcggat ggcggacgaa gtggtcgaca accccgcgcc cggcaccgat cccgccgtcg
    12781 cgctggacga cgtcgccgtc atggtcgggc aggtcttcga cggcggcaca cccgccgatc
    12841 cggtgctggc cgcgctcgcc gacacggtgc ggcgccacga cctggaccgc gaactgttcg
    12901 acgcgttcct gtggtccatg gcgatggacc tcaaggtcac cgagtacgcg acctacgccg
    12961 acctcaagga gtacatccac ggttcggccg aggtgatcgg cctgcagatg ctgccggtct
    13021 tcggcaccgt ggtaccggtc gaggaggcga tgcccggtgc ggccgcgctc ggtgaggcgt
    13081 tccagctgac caacttcctc cgcgacgtcg gcgaggacct cgaccgggga aggctgtatc
    13141 tgcccaccgg tgaactggcc gcgttcggcg tcgaccgcga actgctcgaa tggtcccgtg
    13201 cgcgcgggct gccggaccgg cgagtgcggc gcgcgctcgc cgtcgcggtg gcgcgcaacc
    13261 gggcggtgta ccgccgcgcc gaagcgggga tcccgttgct gcgcccggaa tcccgtgact
    13321 gcgtgcggac cgcgctcacg ctgtacgaag gcatcctcga cgagatcgcg gccctcggtt
    13381 acgacgtgct gaacacccgc gccgtcgtcc ctcgccgtcg tcgcgcggct gtcgccctgc
    13441 cgaggctgct ggcgagcacg tggagcaact ccaggcttaa ggttcggtca tgacctctgc
    13501 ttcgaacagg aagatccgga tcggcgtcca gctgcagcct cagcacgccg agtacaaggc
    13561 gatccgccgg gcggcttcgg aggccgaaga cctcggcgtg gacatcgtct tcaactggga
    13621 ccacttctac ccgctctacg gcgagcccga gggcctgcac tacgagtgct ggaccatgct
    13681 gggcgcctgg gcggagtcca cgtcacgggt cgagatcggc gcgctggtga cgtgcaacag
    13741 ctaccgcaac ccggaactgc tcgccgacat ggcccgcacc gtcgacaaca tctccgacgg
    13801 acggctgatc ctcggcatcg gctccggctg gttcgagaag gactacgacg agtacggcta
    13861 cgagttcggc accgccggcg ggcggctcga caacctcgcc gaggcgctcc cgcgcatcga
    13921 gagcaggctc ggcaagctga acccgcagcc ggtccgcgac atcccggtgc tgatcggtgg
    13981 cggcggcgag aagaagacgc tgcgcctggt cgcgaagcac gccgacatct ggcacggctt
    14041 cggcgacccg gaggttgtgg agcgcaaggt gaagatcctc gaccagcact gcgccgacgt
    14101 cggccgggac ccgaaggaga tcgagcgttc ggtcgccgtc gaaggcgagc cggaggagct
    14161 gggtccgaag ctgctggagc acggtgtctc actgttcacc gtggcgaccg gcgggccgga
    14221 ctacaacctc gacaagctgc ggtcctggat cgcttggcgg gacaagcagg gctgagctct
    14281 ggggcgaggc gaaagtccgt gaaggcctcc ttccctactc tcaaggtagg gaaggaggcc
    14341 ttcacggaca gtgcggctga atggacgaca ggcgtgactg gctggacgac acgcttggct
    14401 ctgctcgccc tcacgagcgt ttccggcggt gcgccgcgac ccgctcccga gtggcgcacc
    14461 gagtcgagca gtaccggcgc gggctccctc cgcccaagtg cgcgaagggt ttcccacagc
    14521 ccgaagctgc acacagccca cccggcggcg cctgacggtc cgccagcagg accgccagca
    14581 ccagcgcgga cgacgtcacc agccacgcgc cccacggtcc gtcgtcggcg gcgtccacgt
    14641 gcagatgcca gccgaacccg gcgtcgtggt cggtcagccg cggcgcgtgc gcgtagcggg
    14701 ccagcagccg gttcagcacc ccggccgcct ccgcggcgtc ccgcgccgcg aagacctcac
    14761 gcagctccga agccgcttca cgcaacgaag cgacatccga aggccccagc tcgacagagg
    14821 tctcgccgtg cgcctccagc acggaccgga ccgcagaaac cgagggctcc ggaacgagca
    14881 ggaccgccag caggtcgacc gcccgctgcg cccccgcgcg cgccgaacgg ccgggtagga
    14941 aatcctgctg cgccgaagtc ataccccact gtaacgtctt gattatgaga agccgttaca
    15001 ggctagccgt ctacttgacc ggcgcgacgg tcgccaggac cggcgacgag ctgtccggac
    15061 ccgcgttgct cttgctgggg ctcagcgtcg acggctcggc agccaccggg tccgcactgc
    15121 tcgcgggcct gacgatctcg gccgcggcgg gcgggccgct gctcggcgcg ctgctcgacc
    15181 gcagtccccg gccgggtcgg ctgctggcgt gggcgttgct ggcctacgcg ggcgggctcg
    15241 gggcggtgct cgccctcgtc gaagtcccgg ccgcgatcgc ggtggccgtc gcggccgggc
    15301 tgctcaaccc cgccttggcg ggcggatgga cggcgcagct gccgaatgtc cgcggcggga
    15361 caccgctggc gagggcgagc gcgctggacg cgatgacgtt caccgccgcg agcctcgccg
    15421 ggccgggact cgccgggctc gtggccgcgt acgccggcgc tccggccgcg gtcgccgtcg
    15481 cgatcacgct ggtcgcggtg gcgttcccgg cggcctggtc gctgcccgcc gtcgaagcga
    15541 agcccgcgaa accgatcctt cgccggctcg ccgacgggtt cgcggtcctc ttccgcaacc
    15601 gctcgctgct gagggccacc gcgacgtcca cggtgtcctt cgtcgggatc ggggtcgcct
    15661 tggtctgcta tccgctgctc ggcgcccagc ggctggggaa tccgggtttc ggcgcgctcc
    15721 tgctcaccgt gctggccgcc gcgtcactga tcgcgaacgc cgtactggcc cgcaaaccac
    15781 caccgccgga cagcaccgtg ctcgtcacca ccgtcctgct gggcgcgagt tttctgctcg
    15841 cggcgaccgg cgacgacgcg gtgaccctgc tggccgcggc cgtactcgcc ggtttcgccg
    15901 agggaccaca actttcggcg cttttcgcca tccggcatcg cgaagcgccc gcggacgtcc
    15961 gggctcaggt tttcacgacg gctgcgagcg tgaagatcac cggactcgcg acgggagcgg
    16021 cggcagcagg accgctgagc gcactctccg taaccgccgc cttgagtgcc gcggcgggtt
    16081 gtcagctgct cgcggctgcg acgtatgtac tggtcaaacc gtccgggcgg actagaacgc
    16141 catcgcctga gcgcgccgct tgacctcggt gccgtggctg gtgcgcagcg cgttgaccgg
    16201 ggtggccccc ggcagcgtgt cgtcctcggc gaagagccag cgcaacatct ccgtccggct
    16261 gaagccggaa tccgcgagca cggtgatcgt gcccgccagg cccttgacca cgccgtcctt
    16321 caccaggaac gcggccggga cgtacaggtc gcccttgcgc cggacggcga tcaggtgacc
    16381 gtcgcgcaac atctggcgga ccttgttggc cgaaacgttc agcgcggtcg cgacctccgt
    16441 gatcgggaga acggccacat ctgcatcgag aacgtcgtcg gcgacgggaa taccactcac
    16501 aggtgacact gtgccacatt ccgtcttccg ctccgttagt acgcttgggt gacgacccgg
    16561 ccatgacgga acgtgtccga ctggtcacgc ataccaccgt ttcgacgaat tgccggaaat
    16621 cgtgatcctc ggcgagccag gtcccgtaca ccagaacatg ggtacttccg tacgatccat
    16681 agccgtgaca cgcacggatc ccacgttggt gggcactctg ctcgagggcc gctaccgggt
    16741 ggacaagctg ctcgcacgcg gtgggatgtc gtcggtgtac cgcggcgtcg acacccgcct
    16801 ggaccgccag gtcgccatca agatcatgga cccgcggttc gccgacgacc gctcgttcgt
    16861 cgagcgcttc gaacgggagg cccgctcggc ggcccggctg caccacccgc acgtggtggc
    16921 ggtgcacgac cagggcttcg acacccccgg cggcgaggag tccggccgcg cgttcctggt
    16981 gatggaactc gtcgacggcg ggaccctgcg cgaactgctc accgaacgcg gcccgctgga
    17041 cgtcgcgctc gcgctgagca tcgccgaacc ggtgctgtcc gcgctcgccg cggcgcacgc
    17101 cgccggactg gtgcaccgcg acgtcaaacc ggagaacgtg ctcatcggcc gcggcggcac
    17161 ggcgctttcg ggcggcgtgg tcaaggtggg cgacttcggc ctggtccgcg cggtcgcgag
    17221 cgcgggcacc acgagttcga gcgtcatcct cggcaccgtc gcctacgtct cgcccgaaca
    17281 ggtctccacc ggcgcgacca cgtccagcgg cgacgtctac tcggccggga tcctgctgta
    17341 cgaaatgctc accggacgcg cgccctacac cggcgacacc gcgatctcgg tggcgtaccg
    17401 gcacgtcaac gacgacgtcc cgcgcccgag cgaactgcgc ccggacatcc cgccgatgct
    17461 ggacgagctg atcctgcgcg ccaccaggcg cgatcccggc cagcgcccgg ccgacgcctc
    17521 ggcgttcctc gccgaactga accacctgcg caccgccctc ggtgtcccgc cggtcccggt
    17581 acccgtgccg ctgcccgcgg acgccgaccg ggagaccgac gccgagcgca ccacccccgg
    17641 catcccggcc gtcccggcgg cgagcccgac cgcggcgacg acggtgctga cgccggtcgc
    17701 cgaagcgacc atgccggtca ccggaccgcg cggaacgcag gcgatgcagc gggagcccca
    17761 cttcgccgcc cagccgcccc ggacctctcc accgcgtccc aaaccacccg cggacgacga
    17821 gaagccgggg tcgcgcaagc gcctctacct gatgatcgcg gccgccgtgg tgatcctcgg
    17881 cggcctgatc ggcgcgttcg ccttcatcct caacgacacc ggcccgacgt cgtcgtcggt
    17941 gccgaagctg gccgggatga accaggccgc cgccggtgac gcgctccggt cggcgaagct
    18001 gacccccgcc tacaccgagg agtacagcga caccgccgcg cagcacacgg tgatccggtc
    18061 cgaccccgcg gcgggcacgt cgctcgcgcc gggcgccacg gtcaacgtcg tgctgtcgaa
    18121 gggccgcccg atcgtgccgg acatccaggc cggcacgagc cagcaggacg cggagacggc
    18181 gatcaaggcc gcgcagctga ccccggccca gggcgagcag gagtacagcg acgtcgccaa
    18241 gggcaaggtg atccgcgtcg acccgagccc cggttcgcag ctgaacatcg gcgggcaggt
    18301 cacgctcatc ctgtcgaagg gccccgagcc gctgccgccg gtcccggacg tcacgggcca
    18361 ggccaaggac gccgccttcc agatcctgca gcaggccggg ttccagccgt tccaggcagg
    18421 cgaggagttc tcggaccagt tcgtcgccgg gcaggtgatc cgcaccgacc cgaagggcgg
    18481 cggcaaggcg agcaaccgcc ggatcggcgt attcgtttcg aacgccgtcg aagtaccgaa
    18541 tgtgaccttc aagcggtggg aagaggcggt ccagatcctg cgccaggcgg ggctggacgc
    18601 cgaccgtgag ggtcacggaa acggcaatgg ccacggcggc ggaaacggtg gtttcgactt
    18661 cgtcgtgcag caggatccgc agccgggcgc caaggtgccg aagggcacga aagtgcggct
    18721 cagggtcttc gggtgacgcg aaaggtgcgg tgaaaccgtt cagtaccggc gcggtcatcg
    18781 gataccgtga accgcatggt ggtcgttgac gacgtgagcg gcaggtcgga caggttcacc
    18841 tcgcgtccgg tcgcacccgg tccacgatga gcttcttcac ggacagcccc cgcggccgcc
    18901 ctctcttccc ggtgccggag caggagctgt tcggctacaa cggccgcccg tgggtggaat
    18961 cgccgcacga gtacatcgtc ccggcgatcc tgccctggtc gatgccgctg ggccgcgccg
    19021 aacggaccat cgtggcgctg cgcggcatcg aggtgtggcc ggagtcggtg accttccagc
    19081 tgtcggtgta cgcgcgggat ctcttgctgg acgagcccgg cgaaggcctg atcgaccatc
    19141 gacgggtccc ggactacaac gcgctgctgg tcggggtgct gttccccgac ggccgccggg
    19201 ccagttcgga gaccatctcc gtgccgtccg ccgccaaacc ggatcagccg gtactgcgcg
    19261 cgcaggggct gggcggcacg tcgttccacg tcgaccacga gatcttcctg tggccgctgc
    19321 cgcccgacgg gccgctggag ttcatcgtcc agtggctcga ccgcgacatc gaggagacgc
    19381 gcaccccgct cgacggcacc gcgatccgcg acgccgccaa ggaggcgagc gagatctggc
    19441 ccggcctgcc cgcgcgggag gcgcacgggc tgccgttccg ccgggtcggg gcgcaggcga
    19501 tgatcacccc cgcctggccc cgcgagtcac aggcgccgcc tccacttccc cagccgaaac
    19561 gcacgtcacc gccgtcgcca ccgcccgctc aagcgacggc ggaccagccg cgacgcggtg
    19621 cgccgctgcc gacccgcctc ccccgccggg ctcgctgacg tatctcgcgt gtccctggcc
    19681 gtgactcgcg tgcttgaagc cggaacacag gagttccgcc tccaagcacg tgagttacgt
    19741 cctcaagcac gtgagttccg ggtgatggct cagcggaacg cttcgacgtt cgccacggcc
    19801 cattccgcat aggtgacacc gggccgtcca gtgagctcct ggacgacacc cgtcggcttg
    19861 tcggggttct cggtgaagta cgcgaagccg tcgaggagcc actccgcgat ctccgccggg
    19921 atcccggcgc cggcccactg cttctccgcc tcttcacggg tgagctcctg aaaggtcacc
    19981 ttctcgccga gcgcggccga gatggcggcg acctgttcac gctgactgat cgccgtcggg
    20041 ccgctcaacg tgtgcttctt gccgacgtgc ccctcggtca ggaggacgtg cgccgcgacg
    20101 gcggcgatgt ccgcgaggtc gatcggcgtc atcgtcgctt cggcgtaggc gtcgcggacc
    20161 acccgctcgg ccttgatcgt ctccgcccag ccgagggtgt tgttcatgaa cgcgcccggc
    20221 cgcaggaacg tccagtcgaa ctccgcctcc cggaccgcct tctcgatgat cgcgtacgcc
    20281 acaccgctcg agttctccac cgggtcgtcg gcgttgctgc ccgacagcgc caccacccgg
    20341 cgcacccctg cctccttcgc cagcttcacg aagtcgtcga ccgtgtccgc cagaggcgcc
    20401 aggtacacgg tctcgatgcc ttcgagggct tccggcaggg tctccggctt gcccagatag
    20461 cccttggcga cctccacctg ctccgggagc gccgccttca ccgggttgac ggtcagcgcc
    20521 cgcaccggcg ccccggcctt caccagttcg ttgaccagca gcctgccgac gcttccggtc
    20581 gcaccggtca ccaggatcgt cacgattccc cactcctttt cgtacgtcct acggtaatgc
    20641 tttaaccgta cctcatacga gaatgtagaa tccagtttca cggccgagtg gagtgtggat
    20701 ggacttcgag cgcagcctcg aactgttgtg gcgtgacagc ggcgagaccc ggcagccgac
    20761 cagggggcgg aagccgaaac tgaccctcga ccaggtgatc gccaccgccg tcgcgctcgc
    20821 cgacggcgcg ggcgaggcga ccgtgtcgat gagccagatc gccaaggagc tcggcgccgg
    20881 cacgatgacg ctctacacct acgtccccgg caagacggaa ctgctcgacc tcatggtgga
    20941 ctcggtgctc gccgaacgcg acctccccgg ccccggcgcc ccgcggcccg acggctggcg
    21001 cgagcaggtg cggctctacg ccgaacgcac gctggccgtg ttccgggcgc atccgtggct
    21061 gcgctcgacg tcgatggtgc gaccggtgct cgggccgggg ctgatggcgg gccaggagta
    21121 cctgatcgcg gccgtgtcgg acatcgggct gcccccgcgc aaggcggcgg ccgccgcgaa
    21181 cagcatcgag atctacgtcc aggcgaacgc gaccctgttc gccgagacgg cgcaggtcga
    21241 gcagcagacc gggcagacga ccgacgcctg gtgggggcag cggtcggtgt tctgggagaa
    21301 gtacttcgac gtcaagcggc atccggcgat gacgcgactg tgggaaagcg gcggctacga
    21361 ggcggagacc tgcgaagccg ccgacgaggc cttcacgttc gggctcgagc gcatgctgga
    21421 cggcatcgaa gcgctcgtcg cccgctgagc gcggttcagg agacggtggg cagatccggc
    21481 gccgagacgt cgaagacctt gccctcgcgc gtgagcagcg cggccaggac cttcgccttg
    21541 cgttcggtgt ccgccgaggt cccccaccgc acggttttcc cgtcggccag cgtgaactcg
    21601 acgctgccgg gcgtcttcgc cgtcgcggtg gtgacctgtt tgagcagctg ctgcgggatg
    21661 acgccgagga cgcctgtcac cgcacgggtc accgggtcgt cggccgacac cgacggcagc
    21721 ttgagctcgg gcagtcccgc gggccgttcc ttgaccgtct tgaacacgac cgccgcgccg
    21781 tcgacgaggt gcacaccgtc gccgccgggg ccgctgtcga agaaggcgat cgcggcgcgt
    21841 tcggtcacgg tgatctcgag ggtgcccggc caggaccggg agacgtcgac ggtggcgata
    21901 ccgggcatct gcgccacccg gtcccggatc tcgtcggtgt ccacgcgcag catcggtttc
    21961 tggtccggca ccgccgccgt ggcacggatc tgttccgcgg gcacggaatt cgccccggcg
    22021 acgtccacct gccgcacgcc cagcatcgag ctgaaccaca gcaggtagac gagagcggcg
    22081 atggtcagca gcgaaagcac tgcgacccag cgccgccgca tctccttgtg ccgggcagga
    22141 cgggctgtgc ggtggcggtc gtgcacggac cgcctgccgc gccgctcctt cagccgttgt
    22201 gtccgctcgg cccgtggagt ccgcttgacc cgttcgccgc gcggacgccg accgggttcg
    22261 gccgggcggc ggcgttcccc ggtctgtgtc atggctgccc gccggccgat gtcatggcta
    22321 gcccgcccgc cggtccagtt cggccaggat ctccgggccg agctgcgtga cgtcgcccgc
    22381 gcccatggtc accagcaggt cgccgggctt gaccaggtcc gccgcgagtt tcgccgcgac
    22441 gtcgaacgcg ggctggtagt gcacggggac cccggagatc cggtcggcga tgagcgcgcc
    22501 gctcacgccg ggttccggct tctcgcgggc cccgaagaca tccagcacga cgacctcgtc
    22561 ggccagcgac agcgcggccg cgaactcgtt cgagaacgtc ttcgtgcgcg agtacagatg
    22621 cggctggaag accacgacga cccggcccgt gccggcggcc gtccgcaccg cgcgcagctg
    22681 cgcgtcgacc tcggtcgggt ggtgcgcgta gtcgtcgtac acccggacgt cgcccgagcg
    22741 gcccttgaac tcgaaccgcc gccggacacc gccgaacgcg gcgagcccgt cggcgagccc
    22801 gtcgaccggc gcgccgagtt cgatcccggc cagcagggcg gcgatcgcgt tcagcgccat
    22861 gtgttcgccc ggcaccgcga cccggaggac gatttcctcg ccctgcaagg agatccggac
    22921 aacgccaccg tccggtgcgg gcacgaagtc caggaccttg gcgtcgtcgg caccggtgac
    22981 cgaacgcccg tagcggcgga cgcggatgcc ctgcgccgaa gcctgcgtgc ccagcgcgtc
    23041 ggcgccttcg tcgtcaccgc agacgacgag cagcccgccc ggttcgatcc ggccgaggaa
    23101 gtcggtgaac accgagacgt acgcctcggc cgtgccgtgg tggtccaggt ggtccggctc
    23161 gacgttcgtc accacggcga ccgacggcga gtaggccagg aacgacccgt cgctctcgtc
    23221 ggcctcggcg acgaagacac cgccctcgcc gtggtgcgcg ttcgcgcccg actcgttgag
    23281 gtcgccgccg atggcgaacg acgggtcgag gtggcaatgc tgcagcgcga cggtcagcat
    23341 cgacgtcgtc gacgtcttgc cgtgcgtccc ggcaatgcag gcgacgcggt ggccttccat
    23401 cagcccggcc agcgcctgcg cgcggtgcag cacggtgatc ccgcggtccc gcgcggccac
    23461 cagttccggg ttgtcgtcct tgatggcggt cga
//
