LOCUS       NZ_KB913032            22880 bp    DNA     linear   CON 28-APR-2024
DEFINITION  Amycolatopsis alba DSM 44262 scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_KB913032
VERSION     NZ_KB913032.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Amycolatopsis alba DSM 44262
  ORGANISM  Amycolatopsis alba DSM 44262
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 9811274)
  AUTHORS   Klenk,H.-P., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Amycolatopsis alba DSM 44262
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: India
            num_replicons                     :: Missing
            ref_biomaterial                   :: DSM 44262
            biotic_relationship               :: Free living
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.05; ALLPATHS v. r41043; Phrap v. 4.24
            finishing_strategy                :: Missing
            environment                       :: Soil
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi10729
            Current Finishing Status          :: Level 2: High-Quality Draft
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2011
            Isolation Site                    :: Soil
            Cell Shape                        :: Filament-shaped
            Motility                          :: Nonmotile
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Gram Staining                     :: Gram+
            Diseases                          :: None
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.05; ALLPATHS v. r41043; Phrap v.
            4.24
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina GAii
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000384215.1-RS_2024_04_28
            Annotation Date                   :: 04/28/2024 01:36:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,988
            CDSs (total)                      :: 8,922
            Genes (coding)                    :: 8,855
            CDSs (with protein)               :: 8,855
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 24 of 67
            Pseudo Genes (incomplete)         :: 49 of 67
            Pseudo Genes (internal stop)      :: 4 of 67
            Pseudo Genes (multiple problems)  :: 10 of 67
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:42:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7120331
            Orig. end                         :: 7143211
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB913032.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 404842
            Source DNA and Organism available from Hans-Peter  Klenk
            (hpk@dsmz.de)
            Source DNA available from Hans-Peter  Klenk (hpk@dsmz.de)
            Organism available from Hans-Peter  Klenk (hpk@dsmz.de)
            Contacts: Hans-Peter  Klenk (hpk@dsmz.de)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22880
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="31"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22880
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22880
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12880](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12880
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(713..1552)
                     /locus_tag="AMYAL_RS0133525"
     CDS             complement(713..1552)
                     /EC_number="3.6.1.27"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005164773.1"
                     /locus_tag="AMYAL_RS0133525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="WP_020635670.1"
                     /transl_table=11
                     /translation="MGWFEALVLGLVQGLTEFLPISSSAHLRITAALAGWDDPGAAFTA
                     VTQIGTELAVILYFSTKIGKILRAWFFSIYKKDWRQDPDARLGWLIIVGSMPIVVLGLL
                     LQDAIDESFRDLRITATTLIVFGLILLVADRIGKQERTLDHLTVPHGLGFGFAQALALI
                     PGVSRSGGTTSAGLLLGYTRAEAAEYSFLLALPAVFGSGLYKLTDIGKDGAPAQWGPTI
                     LATLVAFGVGYAVIAWLMSYIKTKSFVPFVIYRLVLGVLLFVLIFTGVLDPQAGPHV"
     gene            complement(1552..2598)
                     /locus_tag="AMYAL_RS0133530"
     CDS             complement(1552..2598)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029605.1"
                     /locus_tag="AMYAL_RS0133530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_020635671.1"
                     /transl_table=11
                     /translation="MRLGLNLGYWGAGNDAANLALAKKADELDYAVVWAAEAYGSDAPT
                     VLSWVAAQTSRIDVGSAVLQIPARTPAMTAMTAATLDTLSGGRFRLGLGVSGPQVSEGW
                     HGVKFASPLGRTREYVEIVRKALSRSRVKYDGEHFQLPLPGGPGKALTLTVHPVREEIP
                     VYLAAIGPKNLELTGEIANGWLPVFFSPEHAGEQLKLIQAGADKAGRSLDGFDVVPTVP
                     LVVGDDWKACADAVRGYAALYIGGMGSREKNFYNQLACRMGFASEAADVQQKYLGRDYE
                     GAMAAVPLEFIDATSLLGPKERIAERMQAFAAAGVTTLTMAPSMPDPESSAHALEVAAE
                     AIELAGVA"
     gene            2735..3700
                     /locus_tag="AMYAL_RS0133535"
     CDS             2735..3700
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029604.1"
                     /locus_tag="AMYAL_RS0133535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /protein_id="WP_026467658.1"
                     /transl_table=11
                     /translation="MEKRQLGRSGLRVSRMALGTMTWGGDTDSEEAASQLVAFVDAGGT
                     LVDTADIYGEGESERVLGGLLGDLVPRDDIVLATKAVARRTDGPFGGGASRGALLSALE
                     GSLRRLGTDHIDLWQLHAWDTTVPVDETLAALDYAVTSGKARYVGVSNYCGWQLATAAA
                     RTSAVAPLVSTQVEYSLLERGVDREVVPAAEHHGIGILPWAPLGRGVLTGKYRSGTPAD
                     SRGASSVFAGYVEHHRTDRAARIVQAVATAADGLGTSPLAVALAWVRDRPGVVAPVVGA
                     RDTGQLTGSLTAEEITLPPAIRSALDDVSAIEVGYPERGL"
     misc_feature    complement(3723..3738)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    complement(3734..3749)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    complement(3734..3749)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.33"
                     /tool="antismash"
     gene            3814..4827
                     /locus_tag="AMYAL_RS0133540"
     CDS             3814..4827
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029603.1"
                     /locus_tag="AMYAL_RS0133540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_020635673.1"
                     /transl_table=11
                     /translation="MGRLSAVSRIAIPLAGALVLSSCGTDDTPNDSLQIVQNPVAVTAA
                     VSPAVTVKPAGSVFAVPGVKALATSETTKALVVAVSEPPSLRIYDLAALDAPKKTVALP
                     GPAERLTVSGSQVLASVPGKSLLAKVSLPDGALETVPVAGQPSAGLADGDATLVSVRDR
                     KVVEVLSKNAAPKTVTGQIYSADDVLNTGDGVVVLDKLRTALFAVDLAEGKIGEGLRAG
                     DGAANAVTDDLGRVFVTDARAGALLAFSTTPLLLRQRYPVPGGAYGIAYDRTRGLAWVT
                     LTERNEVVGFDVRGGEPIEKHRFPTVRQPDSVTVDEQSGRVVVGSAIGEGIQVITP"
     gene            4824..5045
                     /locus_tag="AMYAL_RS0133545"
     CDS             4824..5045
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029602.1"
                     /locus_tag="AMYAL_RS0133545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5703 family protein"
                     /protein_id="WP_016334446.1"
                     /transl_table=11
                     /translation="MTVVDEAVVEGDWEYRRLQLPPGVSRRAAATQLSIHAEFAGWELS
                     TVRLYSDGTRRVWLRRKRTATPLPGLIT"
     gene            complement(5038..5781)
                     /locus_tag="AMYAL_RS0133550"
     CDS             complement(5038..5781)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-113). E-value:
                     8.7e-11. Score: 34.4. Matches aSDomain:
                     nrpspksdomains_AMYAL_RS0133550_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635675.1"
                     /locus_tag="AMYAL_RS0133550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_020635675.1"
                     /transl_table=11
                     /translation="MGHEFEISDRVEVDATPEQVWDAIATGPGITSWFMGRNEVEGGVG
                     GTVKTAFGGYEPASAITAWDPLERLVYGTEPEPDGRFVAYEFLIEGRSGGSTVLRTVTS
                     GFLPGDDWEDEFEAMSAGGELFLRTLVEYLNGFAGRQAAPVTVFGPMIEDWDSAWLKLG
                     RELGLAGRPEMGDRVRLSTSGVSTVDGEVYFANAQTVGIRTPDALLRFVRGFVGPMVAM
                     HHLFGDVDSAEQDGIWADWLGRVFR"
     aSDomain        complement(5443..5769)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMYAL_RS0133550_Polyketide_cyc2.
                     1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="8.70E-11"
                     /label="AMYAL_RS0133550_Polyketide_cyc2.1"
                     /locus_tag="AMYAL_RS0133550"
                     /protein_end="113"
                     /protein_start="4"
                     /score="34.4"
                     /tool="antismash"
                     /translation="FEISDRVEVDATPEQVWDAIATGPGITSWFMGRNEVEGGVGGTVK
                     TAFGGYEPASAITAWDPLERLVYGTEPEPDGRFVAYEFLIEGRSGGSTVLRTVTSGFLP
                     GDDWE"
     gene            complement(5782..6378)
                     /locus_tag="AMYAL_RS0133555"
     CDS             complement(5782..6378)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005164788.1"
                     /locus_tag="AMYAL_RS0133555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_020635676.1"
                     /transl_table=11
                     /translation="MFSVAVIEDAEAAEVSLDPVRARLLAELAEPASATMLAARVDLPR
                     QKVNYHLRALEKHGLVELVEERRKGNVTERMMRATASSYVISPTALSAVQPDPAQSPDR
                     LSARWLLAVAGRLVRDVGVLITGSTKARKRVATFAIDGEVRFSSAADRAAFAEELTVAI
                     TNLVSKYHDEDAEQGRDHRIVVAVHPSVKTEPEEH"
     gene            complement(6419..7297)
                     /locus_tag="AMYAL_RS0133560"
     CDS             complement(6419..7297)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (24-273). E-value:
                     6.8e-26. Score: 83.3. Matches aSDomain:
                     nrpspksdomains_AMYAL_RS0133560_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334450.1"
                     /locus_tag="AMYAL_RS0133560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_020635677.1"
                     /sec_met_domain="PF00561 (E-value: 1.3e-17, bitscore: 63.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.9e-20, bitscore:
                     73.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGLLAADGTPLHFERWGDSSAPVTVVLLHGYALDRRSWRAIGPV
                     LAEAAEEPLAVLAYDQRGHGESGEVRAASATMGQLADDLAEVLEKVIPDGKIVLVGHDM
                     GGLAILSLAQRHPDAFAARVAGIGLLAMSAGGVTPDAIWPNALGKLGRDLEMVFGTKLI
                     GLVREHTSKAVTAGLRWWLFGDDPVPGDVELAVRMIRGNWPQTVSAFRPALDAYTRESA
                     LSQVGAVPVTAIVGERDKLVPAADVEELAGAVENGTSVVLPGVGHVVPLEAAPQVVPRL
                     LALANRARRQD"
     aSDomain        complement(6479..7225)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMYAL_RS0133560_Abhydrolase_1.1"
                     /evalue="6.80E-26"
                     /label="AMYAL_RS0133560_Abhydrolase_1.1"
                     /locus_tag="AMYAL_RS0133560"
                     /protein_end="273"
                     /protein_start="24"
                     /score="83.3"
                     /tool="antismash"
                     /translation="TVVLLHGYALDRRSWRAIGPVLAEAAEEPLAVLAYDQRGHGESGE
                     VRAASATMGQLADDLAEVLEKVIPDGKIVLVGHDMGGLAILSLAQRHPDAFAARVAGIG
                     LLAMSAGGVTPDAIWPNALGKLGRDLEMVFGTKLIGLVREHTSKAVTAGLRWWLFGDDP
                     VPGDVELAVRMIRGNWPQTVSAFRPALDAYTRESALSQVGAVPVTAIVGERDKLVPAAD
                     VEELAGAVENGTSVVLPGVGHVVPLEA"
     gene            complement(7297..8619)
                     /locus_tag="AMYAL_RS0133565"
     CDS             complement(7297..8619)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005164792.1"
                     /locus_tag="AMYAL_RS0133565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_020635678.1"
                     /transl_table=11
                     /translation="MTEPNLIEAAAEEAVTLTSELIRIDTTNTGDPDTLVGERAAAEYV
                     AEKLTDAGYEITYVESGGKNRHNVIVRLPGADPSRGALLIHGHLDAVPADASEWSVHPF
                     SGAIQDDYVWGRGAVDMKDMLGMTLALARHYKINNIVPPRDLVFAFLADEEAGGKYGAQ
                     WLVENRPELFEGVTEAISEVGGFSITLKDNVRAYLIETAEKGIRWMKLRVRGTAGHGSM
                     IHRDNAVTKLSEAVARLGNHRFPLVMTDSVREFLDGVTEITGWDFPEDDIEGSVAKLGN
                     ISRMIGATLRDTANPTMLTAGYKSNVIPSVAEASVDCRILPGRLEAFNAELEEILGPDI
                     EKEWMELPPVETTFDGALVDAMTNAVLAEDPGARTLPYMLSGGTDAKSFQSLGIRNFGF
                     APLQLPADLDFSALFHGVDERVPVDALKFGVRVLDRFLRSA"
     gene            complement(8733..9680)
                     /locus_tag="AMYAL_RS0133570"
     CDS             complement(8733..9680)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005157344.1"
                     /locus_tag="AMYAL_RS0133570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="5,10-methylenetetrahydrofolate reductase"
                     /protein_id="WP_020635679.1"
                     /transl_table=11
                     /translation="MVDHSDSAAFRKLVTGAESGILLFGITPPRLSADPERIREITAAT
                     LGRLAALDMDGLALYDIDDESDRNPAERPFPYLPTMDPATYHADYLDGWNRSAIIYRCV
                     GKYAEAELRTWLQTADSDRVHGVFVGASSKDKPALTTLSEAQALRRDVRPDLLLGGVAI
                     TERPEEHLRLIAKQEAGCAYFISQVVYNADAAKSMVSDYFYACRERRLTPKPVLFTLSV
                     CGSTKTLAFLEWLGVDVPRWLENSLRHADDTLAESYEQCMATARDLIAFCRKLGMPFGF
                     LVESVSIRKAEIEASTALADELSRLLERGRPCAR"
     gene            10001..12880
                     /locus_tag="AMYAL_RS0133575"
     CDS             10001..12880
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029581.1"
                     /locus_tag="AMYAL_RS0133575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_020635680.1"
                     /sec_met_domain="DUF4135 (E-value: 1.1e-98, bitscore:
                     329.9, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.4e-12, bitscore:
                     46.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGVTPQTSATSLPLSWWVHGQTPRERNADKPVWADFAEHAVTTL
                     LPERPPVRDWRVEFAGVFRSFVAAACQAAVPDDLADADVEALRRGFAAQLDQHLLKLSV
                     RTLVLELHRARKAGTLQGETPEERFSDFVRRQSTPAGLARLFGEYPVLARLLAQSCLHA
                     AEANAEMLTRFAADAAALPGSVVDGELGTLVEVAGGIGDSHARGRSVKLLRFSSGAKVI
                     YKPRPLILHERFTDVVDQLNKRLPGLELRTADALPRDGYGWLRFVEYRPCADIADVDRF
                     YRRQGILLALLHALDATDVHYENIIACGDQPVLIDIETLFQPSPPDPPEGDPAAAMLAR
                     SVQRTLLLPQLFAGEHGAVDISGLAGRGGKLPTDRVDWADPGTDHMRLVRVPGELAGGN
                     NLPRLDGRDVTPAEHSAALLAGFRLGYDAISTARDELAEHLRRCAEDPIRVLIRPTNFY
                     FRLLDETTHPDLLRDAEDRDRAFDLLEEDSAGEEKLLRLVPHERADLWTGDVPMFTSNP
                     GSTSLLDSRGDSVEGVVDRPSLDTVLAKVADMDPLDQRDQEWLIAATLAISTAIDGHHG
                     SGETAETAVPNQAPDAERLLVTACGIADHIVANAFSDEHRSNWLGIELVDDRYWTVLPM
                     GAGLGEGYCGVALFLAQLAELTGIARYRDLAAYAISPLPSLFATLRADPELAATAGCGG
                     LLGLGGVAYTIARLSTLVGLPAGDLIEQAVDLMPDATHGTPSGFTTGLAGGVASMRSVY
                     VQTGLESALAKADRYAGLLLDRERPLGTGFARGSAGIDWVLRAHARTGEESPGKADDRA
                     ESTGGWCDGLAGAALGQAAQLPDPAHSLQLDRTVKRLSDGAPMKDLSLCHGESGVLEVL
                     CVLAENGHTGAAAAARRRTGHLLAAIDQRGARCGTPGAIPAPGLLTGLAGIGYGLLRLG
                     FGDRVPSALLLRPDRPHPAATVIPPVNRV"
     gene            12895..13089
                     /locus_tag="AMYAL_RS0133580"
     CDS             12895..13089
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029580.1"
                     /locus_tag="AMYAL_RS0133580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_020635681.1"
                     /transl_table=11
                     /translation="MYERDLSATEDALGAVNLPRALEVGSRNHALAGSKPRLSANPLAT
                     LSSDPGSPSVVSVFTGGWI"
     gene            13179..16067
                     /locus_tag="AMYAL_RS0133585"
     CDS             13179..16067
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029579.1"
                     /locus_tag="AMYAL_RS0133585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_020635682.1"
                     /transl_table=11
                     /translation="MGIRSSRVIGRDAELTELSGALDRAIAGRGGAIFLVGEGGIGKSR
                     LAIEAASRAVTADIPVLQGRAGSIGPLVPFRPLTQALWSHFRGGGPPEAAELDPFVPVL
                     AQLVPDWSQGDRPRESGSLLVLAEAVFRLLAVTSRGRGALLVLDDLQDADAETLFILEY
                     LVDNLAAAQTLFVGTLRNEPSDALRLATTGAQRMSCTVLELDRLGLADTRALAAACLET
                     EPGRLPAPAAELLWRNSAGLPFIVEELLHGMVNDGLLVEGRDGWRVIGELRARVPAALI
                     TSIGVRMEQLGEQAGELLSVAAIIGRRFPLPVVQRVTGTNDRTLHNHLSAAVSANLVTT
                     DETTPGWYAFRHPLTAEALLARQSPARKAALARQAADAVEKLYPGLPGDLCALAASLRL
                     TALDERAAGHLFAETGRRALDAGAADSAVTMLTKAVDLLAGADAGDRAEVLETLLYALG
                     QTGQFDRAVELSDGFGEIGTLERAAKLHTQLAWAAYIAGRHDECLGQIERARAPLGSAI
                     SPAQQAALDAVEANLWLDVPGRTGTAERLARQAWKVAEETRQPFVVCQALQVLGMLALP
                     RDLTESEHYMQLARRTAEDNHLHHLRTQALVRLGGHRVLMNGDEQTLLLARDDAQRTGS
                     ITLHCAVDSVRTMHAILRCEFDTAHALLEENLAVLGRLRLTALLQYAHMTRAMSAGHRA
                     DRPAMEQALADFRESGGENAQEMVLSIGLAQVFCSLLEEDFERARRELDQVTELEDRRP
                     SRFHLAGQHGLRTLVDTLGGADCPEAGSAMSEMRWNRQFVEFAHAVEHGRRGEAVEAGQ
                     AVTAALETSAPYPLARYLGLRLIAEPAAADGWGDPAGWLKEAEEYFHGRGIQAVAAACR
                     SLLRKLGAPVRQRRAGVDRVPGDLRAAGVTVREYEVLVLLAERMGNKDIGARLHISPRT
                     VEKHVASLLAKTGLADRSALAERAAGPRPGML"
     gene            16071..16310
                     /locus_tag="AMYAL_RS0133590"
     CDS             16071..16310
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334468.1"
                     /locus_tag="AMYAL_RS0133590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutaredoxin domain-containing protein"
                     /protein_id="WP_020635683.1"
                     /transl_table=11
                     /translation="MNDLTVYGAVWCPDVKRSRALLDAKGVEYDYVDVEADTGAEEIVR
                     ALQNGERRIPTIVWPDGTHLVEPSDDELTAHLNR"
     CDS_motif       16071..16097
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNDLTVYGA"
                     /locus_tag="AMYAL_RS0133590_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       16098..16310
                     /prepeptide="core"
                     /locus_tag="AMYAL_RS0133590_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-0.60"
                     /molecular_weight="7793.5"
                     /monoisotopic_mass="7789.0"
                     /core_sequence="VWCPDVKRSRALLDAKGVEYDYVDVEADTGAEEIVRALQNGER
                     RIPTIVWPDGTHLVEPSDDELTAHLNR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNDLTVYGA"
                     /leader_location="[16070:16097](+)"
                     /alternative_weights="7811.6"
                     /alternative_weights="7829.6"
                     /alternative_weights="7847.6"
                     /alternative_weights="7865.6"
                     /alternative_weights="7883.6"
     gene            16307..16537
                     /locus_tag="AMYAL_RS0133595"
     CDS             16307..16537
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005168317.1"
                     /locus_tag="AMYAL_RS0133595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferrous iron transport protein A"
                     /protein_id="WP_020635684.1"
                     /transl_table=11
                     /translation="MTLPDVPVGTRVVVRYRIEGGFTDALGYLRSRDDAECTVETKRGL
                     ATIRLADIVLAKTVPPPPAPRGSRKDTFGSP"
     gene            complement(16613..17932)
                     /locus_tag="AMYAL_RS0133600"
     CDS             complement(16613..17932)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334473.1"
                     /locus_tag="AMYAL_RS0133600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_020635685.1"
                     /sec_met_domain="Aldedh (E-value: 1.7e-80, bitscore: 269.8,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISSDASAIVGDLRELFRSGVTKPVTWRRKQLAGLRALLTEQADV
                     FIKALYADLRKNAVEAKRAEIALVRNEIDHTLENLDSWLTPEPADIPQPLRPGAGRVVR
                     EPLGVALIIGPWNYPLQLVLAPLVGALAAGNCAVVKPSELSPNTSAAIAEHLPAYVEGV
                     RVVEGAIPETTALLEQKFDTIFYTGNGTVGRIVMAAAAKHLTPVTLELGGKSPAIVEPG
                     ADLAVTAQRLAYGKFANAGQTCVAPDYVLAIGDTGPKLAEHLAETVEAMFGADPATSDS
                     YGRIISTRHHDRLAALLDDGTAVVGGKADRDEKYIAPTVLTDVSPDAPVMRDEIFGPIL
                     PIIEVPDVDAALAFVNERDKPLALYAFTESDETKRRIETETSSGGLVFGAAIIHLAAPE
                     LPFGGVGESGMGRYHGRYSIDNFSHVKAVLDKPLASGKAT"
     misc_feature    complement(17933..17951)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.57"
                     /tool="antismash"
     gene            complement(18059..20392)
                     /locus_tag="AMYAL_RS0133605"
     CDS             complement(18059..20392)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635686.1"
                     /locus_tag="AMYAL_RS0133605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="chitobiase/beta-hexosaminidase C-terminal
                     domain-containing protein"
                     /protein_id="WP_020635686.1"
                     /transl_table=11
                     /translation="MDRIFVQPKRRKGVRGALALGLSALLIAAGLGGATAAAADYSQSA
                     ASLNATQAQFSFTPATTARYVDIHYTGVPGVGQQNVRMTDSGGTWRHTVGSLAAGTVLD
                     YWFTYEKNGPQYDTPHFGYTHGGSGTTVASPTFDPPGGSYPSARSVTLSSATAGATIRY
                     TVDGSTPTASSTVYTGPITVSASSTISAIALKSGSANSAVASASYTIGSTQATCPAQAE
                     VPDFGPNVRIFDPGMSASSIQAKLDADFNAQKDTLTAQFTERRYAHLFKPGVYNGIHDD
                     VGYYTSVAGLGQNPGDVVINGDVTVDAFNESDKGVALQNFWRSTENLAVVPSSGATRWA
                     VAQAAPFRRMDIRGGLNLFPASYGFASGGYTADSKVSGKTASISQQQWYTRDSSYGSWE
                     GGVWNMVFSGTNGAPANTFPNPPETTLGTTPVSRDVPYLYLDGSGKYRVFLPSLRTNAS
                     GPSWANGGTPGSSLPMSQFYVVKAGDTASSINNALSQGCNLFFTPGVYHLNQTLNVTKA
                     NTVVLGVGYPTLVPDNGVDAMKVADVDGVRLKGLLFDAGTTNSQSLLTVGPAGSAANHS
                     ANPTTLQDVFFRIGGQIAGKATNSLIVNSRDTIIDHIWAWRADHGNAGTYGWTANTGDT
                     GVVVNGDNVLATGLFVEHYQKYQVIWNGQNGRTIFFQNEIPYDVPDQAGWKSPNGLNGY
                     AAYKVGDNVTTHEAWGLGSYCFFNDNPAVNLYHAFEVPNRSGVRFHNLVTVSLNYKGTI
                     THVINDAGAVTPPGTTPSNLVSYP"
     misc_feature    20455..20468
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    complement(20499..20514)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.49"
                     /tool="antismash"
     gene            complement(20582..21037)
                     /locus_tag="AMYAL_RS0133610"
     CDS             complement(20582..21037)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007031587.1"
                     /locus_tag="AMYAL_RS0133610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_020635687.1"
                     /transl_table=11
                     /translation="MVLRTSPPSRAHLRLLAEADAAPPARRRDLYAEIADRRLAAILAA
                     EDVAEEHGLSAHVRTTCYVHRCWVHQCVSDPMHVLIVTGHRWCRRCDRTVDVEVDETFP
                     GSVELSCDGCGVPPDTAANREVLLACRTSLSAMHGGEASTLYVVPDC"
     gene            21206..22036
                     /locus_tag="AMYAL_RS0133615"
     CDS             21206..22036
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059163.1"
                     /locus_tag="AMYAL_RS0133615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_020635688.1"
                     /transl_table=11
                     /translation="MLTKVAVVATATALSFGVAAPASAEVAAAALPAASMEAVLKAAQI
                     DPRRADSALTPGAKDSVLLVEQALSAKGLLDQQYVDGHFGTSTITAYSSYQKSLGYTGI
                     DASGLPGKTSLEKLGEGRYTVTATVAAGSRLTYHGETMNTRTKAMLVKAEGLLGRQLTI
                     TQGSYNPGGVGASAGTHDGGGALDIGVEGMSSATRTDVARKLRQVGFAAWVRTPAQGFA
                     YHIHAIALSDPDLSSGAQHQAGDYYLGYNGLAGRGSDDGPAVSPKLTWEEYQRG"
     gene            22148..22771
                     /locus_tag="AMYAL_RS0133620"
     CDS             22148..22771
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029566.1"
                     /locus_tag="AMYAL_RS0133620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="WP_020635689.1"
                     /transl_table=11
                     /translation="MEDRPVGQWLDELASKASTPGGGAGAAMNAAVGAALVSMVCNLTI
                     GKPKYAEHEATMTEALAKAEDLRGRALGLAAEDAAAFEAVVAAYKLPKATDEEKQARTA
                     AIQAALVGAAEVPLRTAALAAEVIDVAASILEGANTNVISDIAVAASSAKSALESGVVN
                     VEVNLASMSDEQLRKETEARLAEYTPAAGRADVLIAQVRERLAR"
     misc_feature    complement(22156..22171)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.16"
                     /tool="antismash"
ORIGIN
        1 ttgaccttgt ccagaccgcg cgcctcggcc agcttcgcga ccgtctggcg gcagcggagc
       61 atcggcgaga ccaccagctc ggcgagcgga accggcgcca ggcgttcgac gagcgcggcc
      121 gcctgcgccc ggccggtgtc gtccaggccg accttgggcg tgcgcccggc gaggacgccc
      181 gaaccgttcg ccgttgactt gccgtggcgc agaaggatca cagtactcac gtggcccacc
      241 ctacgtgtcc tgctttgccc tctctcgcgt ttcgtcctcc gggagggcgc gggcggggtg
      301 gtctcgtgag tggcaaagct ggttctgacg gacttgtatt tgcttacccg ctggtgtgac
      361 tggcggtcga gcgtggaggt tttgggacgt tcaacgtcct ggatcctcca cgctcggcct
      421 gcttcgtctc ggtgccgggt cgggcttgtg ctggatgcgg gtgtggtcca cgggggaaga
      481 ttgtctgccc cgcaacggtg cggaaacgcc accgtccgca ggtcaggcct aggtacgcaa
      541 atacgggtcc gccctaacgc tccttaccac tcacgaggcc cacgcctcct ggggtctggt
      601 gcggtctggc ggggaggtcg tgttgcgaaa gccacgttcg caacgttgaa ggttgcgaac
      661 gtggctttcg caacgcgtcc agcggggcca cgcacgaggc ccaacggcag ggctacacgt
      721 gcgggccggc ctgcgggtcc aggacgccgg tgaagatcag cacgaacagc aggacaccga
      781 gcacgagccg gtagatcacg aacggcacga agctcttggt cttgatgtac gacatcagcc
      841 aggcgatcac cgcgtagccg acaccgaacg cgaccagcgt cgccaggatc gtcggccccc
      901 actgggccgg ggcgccgtcc ttgccgatgt cggtcagctt gtacaggccc gagccgaaca
      961 ccgccggcag cgccagcagg aacgagtact ccgctgcctc agcgcgggtg tagccgagca
     1021 gcagcccggc gctggtggtg ccaccggagc gggagacgcc ggggatcagc gcgagcgcct
     1081 gcgcgaaccc gaacccgagg ccgtgcggca cggtcaggtg gtcgagggtg cgctcctgct
     1141 ttccgatgcg gtcggccacc aggaggatca agccgaacac gatcagcgtg gtcgcggtga
     1201 tccgcaggtc acggaaggac tcgtcgatgg cgtcctgcag cagcaggccc agcaccacga
     1261 tcggcatcga gccgacgatg atcagccagc cgagccgggc gtcggggtcc tgccgccagt
     1321 ccttcttgta gatcgagaag aaccaggcac ggaggatctt cccgatcttg gtcgagaagt
     1381 acaggatgac cgcgagttcg gtgccgatct gggtgaccgc ggtgaaggcg gcgcccggat
     1441 cgtcccaacc ggcgagcgcc gcggtgatcc gcaggtgcgc gctggaggag atcggcagga
     1501 actcggtcag gccttggacg aggccgagga ccagtgcttc gaaccagccc atcaggcgac
     1561 acccgccagt tcgatcgcct cggcggcgac ctcgagagcg tgtgcggagc tctcggggtc
     1621 cggcatggag ggagccatgg tcagcgtcgt gacgcccgcc gcggcgaagg cctgcatccg
     1681 ttcggcgatc cgttccttcg gccctagcag cgacgtcgcg tcgatgaact ccagcgggac
     1741 ggccgccatg gcgccctcgt agtccctgcc caggtacttc tgctggacgt cggccgcttc
     1801 gcttgcgaag cccatccggc aggcgagctg gttgtagaag ttcttctccc ggctgcccat
     1861 cccgccgatg tacagcgccg cgtagccgcg gaccgcgtcg gcgcaggcct tccagtcgtc
     1921 gccgaccacg agcgggacgg tggggacgac gtcgaagccg tcgagggagc gcccggcctt
     1981 gtccgccccc gcctggatca gcttcagctg ttcaccggcg tgctcgggcg agaagaacac
     2041 cggcagccag ccgttcgcga tctcgccggt cagttcgagg ttcttcgggc cgatcgcggc
     2101 caggtacacg gggatctctt cgcgcacggg gtgcacggtg agggtcagcg ccttgccggg
     2161 cccgccgggc aggggcagct ggaagtgctc accgtcgtac ttgacccggc tgcggctcag
     2221 cgccttgcgg acgatctcga cgtattcgcg ggtgcggccg agcggcgagg cgaacttcac
     2281 gccgtgccag ccttcggaga cctgcgggcc ggagacaccg aggccgaggc ggaaccggcc
     2341 gcccgacagc gtgtccaggg tcgcggcggt catcgcggtc atcgccgggg tccgcgcggg
     2401 gatctgcagc accgcgctgc ccacatcgat ccgtgaggtc tgcgccgcca cccaggacag
     2461 caccgtcggc gcgtccgagc cgtacgcctc cgcggcccag acgaccgcgt agtccagttc
     2521 gtccgccttc ttcgccaatg ccaggttggc cgcgtcgttt cccgcgcccc aatagcccaa
     2581 gttcagtccg agtcgcacgg cgagaatgta tccatcggag tgtcatcact ccgttcaggg
     2641 tgttgacagc cgatgacccg cccggtggta ctcgatcacg acacgctcac ctgctccgcg
     2701 tcccgcactt gccttccggc taggctcgcc cgtcgtggaa aagcgacagc tcggccggtc
     2761 gggactgcgg gtctcgcgga tggccctcgg gaccatgacg tggggtggcg acaccgactc
     2821 ggaggaggcg gccagccagc tggtcgcgtt cgtcgacgcc gggggcaccc tggtcgacac
     2881 cgccgacatc tacggcgaag gcgagagcga acgcgtcctc ggagggttgc tcggcgacct
     2941 cgtaccccgt gacgacatcg tgctcgccac caaggcggtc gcccgccgca ccgacggccc
     3001 gttcggcggc ggggcctcgc gcggtgccct gctgagcgcg ctcgaaggtt cgctgcgccg
     3061 gctcggcacc gaccacatcg acctgtggca gctgcacgcc tgggacacca ccgtgccggt
     3121 cgacgagacc ctcgccgccc tcgactacgc cgtgaccagc ggcaaggccc gctacgtcgg
     3181 cgtctccaac tactgcggct ggcagctggc gacggccgcg gcccgcactt ccgccgtcgc
     3241 tcccctggtc tcgacgcagg tcgagtactc gctgctggag cgcggggtcg atcgcgaggt
     3301 cgtcccggcc gcggagcacc acggcatcgg catcctgccg tgggcgccgc tgggccgggg
     3361 agtgctcacc ggcaagtacc gcagcgggac gcccgccgat tcgcgcggcg cttcgagtgt
     3421 tttcgcgggc tatgtcgaac atcaccggac cgatcgcgcg gcccggatcg tgcaggcggt
     3481 cgcgacggcc gccgacggcc tcggcacctc cccgctggcc gtcgcgctgg cctgggtccg
     3541 cgaccggccg ggagtggtcg cgcccgtggt cggggcccgt gacacgggtc agctgaccgg
     3601 ttcgctcacc gccgaggaga tcacgctccc gcccgccatc cgctcggcgc tcgacgacgt
     3661 cagcgcgatc gaggtcgggt acccggaacg cggcctctga gccgtctcga atactggatt
     3721 aggtgactgt tgggtgacac agacgtgacg cggtggggtt tccgggggat gctggacaag
     3781 tccgttcgac gagtagcagg tggaggcacc aaggtgggtc ggctgtccgc cgtttcccgg
     3841 atcgcgatcc cgctcgccgg tgccctggtg ctctcgtcct gcggtacgga cgacaccccg
     3901 aacgactcgc tccagatcgt gcagaaccct gtcgcggtga cggcggccgt ctcccccgcg
     3961 gtgacggtca agcccgccgg ttcggtgttc gccgtgccag gggtgaaggc gctggccacc
     4021 agcgagacga ccaaggccct cgtggtcgcc gtctcggagc cgccttcact gcgcatctac
     4081 gacctcgccg ccctcgacgc gccgaagaag accgtggccc tgcccggccc ggcggagcgg
     4141 ctcacggtct cgggttcgca ggtgctcgcc agcgttcccg gcaagagcct gctggcgaag
     4201 gtctccctgc ccgatggcgc gctggagacg gtcccggtcg cggggcagcc atcggccggt
     4261 ctcgccgacg gcgacgcgac gctggtgtcg gtccgggacc gcaaggtcgt cgaggtgctg
     4321 tcgaagaacg cggccccgaa gaccgtcacc ggccagatct acagcgccga cgacgtgctg
     4381 aacaccggtg acggcgtggt cgtgctcgac aagctgcgca ccgccctgtt cgccgtcgac
     4441 ctcgccgaag gcaagatcgg cgagggcctg cgcgcaggcg acggcgccgc caacgctgtc
     4501 accgacgacc tcggacgcgt cttcgtcacc gacgcgcgag cgggcgcgct gctggcgttc
     4561 tccacgacgc cgctgctgct gcgccagcgt taccccgtcc ccggcggggc gtacggcatc
     4621 gcctacgacc gcacccgtgg cctggcctgg gtcaccctca ccgaacgcaa cgaggtcgtc
     4681 ggcttcgacg tccgcggcgg ggagccgatc gagaagcacc ggttccccac cgtgcggcag
     4741 ccagattcgg tcaccgtcga cgagcagagc ggccgtgtgg tcgtcggctc ggccatcgga
     4801 gaagggatcc aggtgatcac gccatgacag ttgtggacga ggcggtggtc gaaggggatt
     4861 gggagtaccg gcggctgcag ttgcctcccg gtgtctcccg gcgggcggcg gcgacgcagc
     4921 tgtcgatcca cgccgagttc gccggctggg agctctcgac cgtccggctc tactccgacg
     4981 ggaccaggag ggtgtggttg cgccgcaagc gcaccgccac ccccctgccc ggtctcatca
     5041 cctgaacacg cggccgagcc agtcggccca aatcccgtcc tgttcggcgg aatcgacgtc
     5101 gccgaacaga tgatgcatcg cgaccatcgg cccgacgaag ccgcggacga acctcaggag
     5161 cgcgtccggg gtccggatcc cgaccgtctg cgcgttcgcg aagtagacct cgccgtccac
     5221 agtggacacc ccgctggtgg acaggcggac ccggtccccc atctccggcc gcccggccag
     5281 gcccagttcc cggcccagct tcagccacgc gctgtcccag tcctcgatca tcggcccgaa
     5341 caccgtcacc ggcgccgcct gccggccggc gaaaccgttg aggtactcga ccagcgtgcg
     5401 aaggaacagc tctccgccgg cgctcatcgc ctcgaactcg tcttcccagt cgtcgccggg
     5461 caggaaaccg ctcgtcacgg tcctcagcac ggtgctgcca ccggagcggc cctcgatgag
     5521 gaattcgtag gcgacgaatc gtccgtccgg ttcgggctcc gtgccgtaga cgagccgttc
     5581 cagcgggtcc caggcggtga tcgcggacgc gggttcgtag ccgccgaacg cggtcttcac
     5641 ggtgccgccg acgccgcctt cgacttcgtt gcgccccatg aaccaggacg tgatgcccgg
     5701 cccggtcgcg atggcgtccc agacctgttc cggcgtcgcg tcgacttcga cccggtcgga
     5761 gatctcgaat tcgtggccca ttcagtgctc ctcgggctcg gttttgacgc tcgggtggac
     5821 ggcgacgaca atccggtggt cacggccctg ctcggcgtcc tcgtcgtggt acttgctcac
     5881 caggttcgtg atcgcgacgg tgagctcttc ggcgaacgcg gccctgtccg cggcggagga
     5941 gaaccgcacc tcgccgtcga tcgcgaaggt cgcgacccgt ttgcgcgcct tggtcgagcc
     6001 ggtgatcagc acgccgacgt cgcgtaccag cctgcccgcc accgcgagca gccagcgcgc
     6061 ggagagcctg tccggcgact gggccggatc gggctgcacg gccgaaagcg ccgtcggcga
     6121 gatgacgtac gaggacgccg tcgcgcgcat catgcgctcg gtgacgttgc ccttgcgccg
     6181 ctcttcgacg agctcgacca ggccatgctt ctccagcgcc cgcaagtggt agttgacctt
     6241 ctgtctcggc agatcgacgc gcgcggccag catcgtggcc gacgccggtt cggccagttc
     6301 ggccagcagc cgggcccgga ccgggtcgag tgagacttcg gccgcttccg cgtcctcgat
     6361 caccgcaacg gagaacatgc caagaaggtg tcaccgaaaa cagaacttgt caagaaagtc
     6421 agtcttgtcg gcgtgcccgg ttcgccagtg ccagcagacg cggcaccacc tgcggggccg
     6481 cttccaacgg cacgacgtgc ccgacaccgg gcagcacgac ggaggtcccg ttctccaccg
     6541 cgccggccag ctcctcgacg tccgccgcgg gcacgagctt gtcccgctcc cccacgatcg
     6601 cggtcaccgg caccgcgccg acctgcgaca acgctgactc ccgtgtgtaa gcgtccagtg
     6661 caggacggaa cgcggacacc gtctgcggcc agttgccgcg gatcatccgc accgccagct
     6721 cgacgtcacc gggcaccggg tcgtccccga agagccacca ccgcagcccg gcggtcaccg
     6781 ccttgctcgt atgctcccgc accaggccga tcagcttcgt cccgaacacc atttccaggt
     6841 cccggccgag cttcccgagc gcgttcggcc agatcgcgtc cggggtgacc ccgcctgcgg
     6901 acatggcgag cagcccgatt cccgccaccc ttgccgcgaa ggcgtccggg tgacgctgcg
     6961 cgagcgacag gatcgcgagc ccgcccatgt cgtggccgac caggacgatc ttgccgtccg
     7021 ggatcacctt ctccagcacc tcggccagat cgtcggcgag ctgccccatg gtcgccgacg
     7081 cggcccggac ctcgccggat tcaccgtgcc cgcgctggtc gtaggccagc accgcgagcg
     7141 gctcctccgc ggcctcggcc agtaccggcc cgatggcgcg ccagctccgc ctgtcgaggg
     7201 cgtagccgtg gaggagcacc acggtcaccg gcgccgacga atcaccccag cgttcgaaat
     7261 gcaggggtgt cccgtcggca gccagcagac cgggcatcag gccgagcgca ggaagcggtc
     7321 gagcacccgc acgccgaact tcagcgcgtc gaccgggaca cgctcgtcga ccccgtggaa
     7381 cagcgccgag aagtcgaggt ccgcgggcag ctgcaacggg gcgaacccga agttgcggat
     7441 cccgagcgac tggaacgact tcgcgtcggt gccgccggag agcatgtacg ggagcgtgcg
     7501 ggcgccagga tcttcggcga ggaccgcgtt ggtcatcgcg tcgacgaggg caccgtcgaa
     7561 ggtcgtctcg accggcggca gctccatcca ctccttctcg atgtccgggc cgaggatctc
     7621 ctccagctcg gcgttgaacg cctcgagacg gccgggaagg atccggcagt cgaccgaagc
     7681 ctccgcgacc gaggggatga cgttcgactt gtagcccgcg gtgagcatcg tcgggttcgc
     7741 cgtgtcgcgc agggtcgcgc cgatcatccg cgagatgttg ccgagcttgg cgacggaacc
     7801 ctcgatgtcg tcctcgggga agtcccagcc ggtgatctcg gtgacgccgt ccaggaactc
     7861 gcggacggag tcggtcatga ccagcgggaa gcggtggttg ccgagcctcg cgaccgcctc
     7921 ggacagcttg gtgacggcgt tgtcgcggtg gatcatcgag ccgtggcccg cggtaccgcg
     7981 cacgcgcagc ttcatccagc ggatgccctt ttcggccgtc tcgatgagat acgcgcggac
     8041 gttgtccttc agcgtgatcg agaagccccc gacctcgctg atcgcctcgg tgactccttc
     8101 gaacagctcg ggccggttct ccaccagcca ctgcgcgccg tacttgccgc ctgcctcttc
     8161 gtcggcgagg aacgcgaaca cgaggtcacg cggcgggacg atgttgttga tcttgtagtg
     8221 gcgggccagc gcgagcgtca tgccgagcat gtctttcatg tcgacagcac cgcggcccca
     8281 gacgtagtcg tcctggatcg cgccggagaa cgggtgcacc gaccactccg aggcgtcggc
     8341 ggggacggcg tcgaggtgac cgtggatcag gagcgcgcca cgcgaagggt cggcgcccgg
     8401 cagccggacg atcacgttgt ggcggttctt gccgccggac tcgacatagg tgatctcgta
     8461 gcccgcgtcg gtgagtttct cggcgacgta ctccgccgcg gcgcgttcac ccaccagcgt
     8521 gtcggggtca ccggtgttgg tggtgtcgat gcggatcagt tcactggtga gggtgactgc
     8581 ctcttcggcg gcggcttcga tcaaattcgg ttcggtcacc aggcattcct accattggtg
     8641 gagcccgccg acccggtgcc accgcgtggt ggacaccgtg ggaaaaccca ccctccgccc
     8701 tgcgcagctc ctccgctttc gctcctcgct catcatcgag cacacggtcg gcctcgttcg
     8761 agcagccggc tcagctcgtc ggcgagggcg gtcgatgctt cgatctcggc cttgcggatg
     8821 gacacgctct cgacgaggaa gccgaacggc atgccgagct tgcggcagaa agcgatcagg
     8881 tctcgtgcgg tcgccataca ctgctcatag gattcggcca gcgtgtcgtc cgcgtggcgc
     8941 agggagttct cgagccagcg cgggacatcg acgccgagcc attcgaggaa tgccagggtc
     9001 ttcgtcgacc cgcacaccga gagtgtgaag aggacgggct ttggcgtgag ccgccgctcg
     9061 cggcaggcgt agaaataatc cgaaaccatg ctcttcgccg cgtcagcgtt gtagacgacc
     9121 tgcgagatga agtacgcaca tcccgcctcc tgcttggcga tcagacgcag atgctcctca
     9181 gggcgttcgg tgatggcgac gccgcccagc agcagatccg gacggacgtc ccggcgcagg
     9241 gcctgcgcct cggacaaagt tgtcagcgcc ggcttgtcct tggaggacgc accgacgaag
     9301 acaccgtgca cacggtccga atccgctgtc tgcagccagg tccgcagttc ggcctcggcg
     9361 tatttgccga cgcaccggta gatgatcgcg gaacggttcc acccgtcgag gtagtccgca
     9421 tggtaggtcg cgggatccat ggtcggcagg tacggaaacg gccgttccgc cggattgcgg
     9481 tcgctttcgt cgtcgatgtc gtagagcgcc aaaccgtcca tgtcgagggc ggccagccgt
     9541 cccagggtgg ccgcggtgat ctctcggatc cgttcgggat cggcactcag ccggggcggg
     9601 gtgatgccga acaggaggat gccgctctcg gcgccggtca ccagcttccg gaaagccgcg
     9661 ctgtcgctgt ggtccaccat gacgcggaag ctagcagttc gccgccgggc ggtggacgtt
     9721 ccctccggcg gcgcgggccg gacccccaga aaccggcccg cgcccggcgc cgcggtgatc
     9781 ccccagcgac cgccgcgcca cctgaccatg gtcgcgccgg gaccggtccc gcgcatgggt
     9841 gccgggaccc catattccgg tcggggcgcc gatgagactc gtacttgcct gattgcacgc
     9901 cccctgccgc ctacccggcc gtcactctcc gggcatcttc gtgcgtgcgc tgaatgtggg
     9961 gggtgccgcc cccatgtgcg tgcccggccg agctgaaacc atgaccggtg tgacgcccca
    10021 gacatcggcg acgtccctgc cgctgagttg gtgggtgcac ggccagaccc cgcgcgaacg
    10081 gaatgcggac aagcccgtat gggccgactt cgccgaacac gctgtcacga cgcttctgcc
    10141 ggagcgccct ccagtccgtg actggcgtgt cgagttcgcc ggggtcttca ggtcgttcgt
    10201 cgctgccgcc tgccaggcgg cggtccccga tgacctcgcc gatgccgacg tcgaggcgct
    10261 ccgccggggt ttcgcggctc agctcgacca gcatctgctc aaactctcgg tccgcaccct
    10321 ggtcctcgaa ctccaccgcg cccgcaaggc cggcactctc cagggtgaaa cgcccgaaga
    10381 gcgcttctcg gacttcgtgc gccggcaatc cactccggcc ggactcgccc ggttgttcgg
    10441 cgagtacccg gttctggccc ggctcctcgc ccagtcctgt ctgcacgccg ccgaagccaa
    10501 cgccgaaatg ctgacccgct tcgccgccga cgccgccgcg cttcccggct cggtcgtgga
    10561 cggcgagctc ggcacgctcg tcgaggtggc gggcgggatc ggcgactcgc acgcgcgagg
    10621 acggtcggtc aaactgctcc gcttctccag cggcgccaag gtgatctaca aaccccgtcc
    10681 gctgatcctg cacgagcgct tcaccgacgt cgtcgaccag ctgaacaagc ggctccccgg
    10741 cctcgaactg cggaccgccg acgcactgcc gcgcgacggg tacggctggc tccggttcgt
    10801 cgagtaccga ccctgcgccg atatcgccga cgtcgaccgc ttttaccgcc gccagggcat
    10861 cctcctggcg ctcctgcacg cgctcgacgc caccgacgtc cactacgaga acatcatcgc
    10921 ctgcggcgac cagccggtgc tgatcgacat cgagacgctg ttccagccgt cgccgcccga
    10981 cccgccggag ggtgatcccg cggcggcgat gctggcgaga tcggtccagc gcaccctgct
    11041 gctcccccag ctcttcgccg gggagcacgg cgccgtcgac atctccgggc tagccggacg
    11101 cggtggcaag ctgccaaccg accgggtcga ttgggccgat cccggcaccg accacatgcg
    11161 actggtccgg gtgcccggcg aactcgcggg cgggaacaac ctcccccgtc tcgacggccg
    11221 cgacgtcacc cccgccgagc acagcgcggc gctgctggcc ggattccggc tcggctacga
    11281 cgcgatctcc accgctcggg acgaactcgc cgagcacctc cggcgctgcg ccgaagatcc
    11341 catccgggtg ctcatccggc cgacgaactt ctacttccgc ctgctggacg agaccaccca
    11401 tcccgacctc ctgcgcgacg cggaggaccg cgaccgcgcc ttcgacctgc tcgaagagga
    11461 ctcggcaggc gaggaaaaac tgctcaggct cgtgccgcac gaacgggccg acctgtggac
    11521 gggcgacgtg ccgatgttca cctcgaaccc cggctcgacg tcgctgctgg attcacgcgg
    11581 cgacagtgtc gaaggcgtgg tcgaccggcc gtcgctggac accgtgctgg cgaaggtcgc
    11641 cgacatggat ccgctcgacc agcgcgacca ggaatggctg atcgcggcca ccctcgccat
    11701 cagcacggcg atcgacgggc atcacggaag cggcgagacc gcggaaacgg ccgtgccgaa
    11761 ccaggcaccc gacgcggaac gactgctggt caccgcctgc gggatcgccg atcacatcgt
    11821 cgccaacgcc ttctccgacg agcaccgctc caactggctc ggcatcgaac tcgtcgacga
    11881 ccgctactgg accgtgctgc cgatgggcgc ggggctcggt gaaggctact gcggtgtcgc
    11941 gctgttcctc gcccagctcg ccgagctgac cgggatcgcg cgctaccgcg atctggccgc
    12001 ctacgcgatc agcccgctcc cgagcctttt cgccaccctc cgggccgacc ccgaactggc
    12061 cgccaccgcc ggttgcggcg ggcttctcgg gctcggtggc gtcgcgtaca cgatcgcccg
    12121 gctcagcact ctggtcggtc tccccgcggg tgatctgatc gaacaggccg tcgacctgat
    12181 gcccgacgcc acgcacggga caccgtccgg gttcaccacg gggctggcgg gcggggtcgc
    12241 ctcgatgcgc tcggtgtacg tccaaaccgg actggagtcg gcgctggcga aggcggaccg
    12301 atacgccggc ctgctgctcg accgcgagcg tccactgggg acgggtttcg cgcgcggttc
    12361 cgccgggatc gactgggtcc tgcgggcaca cgcccggacc ggcgaagaat cgcccggaaa
    12421 ggcggacgat cgggcggaaa gcaccggcgg ctggtgcgac ggtctcgcgg gcgccgccct
    12481 cggccaggca gcccagctgc ccgatcccgc ccactccctc cagctggacc ggacggtcaa
    12541 acgactgtcc gacggggcac ccatgaagga tctcagcctg tgtcacggcg agtccggagt
    12601 gctggaagtg ttgtgcgtgc tggcggagaa cgggcacact ggcgccgccg ccgcggcgcg
    12661 tcgccggacc ggtcatctgc tcgccgccat cgaccagcgc ggcgcgcgct gcggtactcc
    12721 cggcgcgatc cccgcgccgg ggttgctgac cggtctggcg ggtatcggct acggcctgct
    12781 gcggctggga ttcggcgacc gggtcccgtc cgcactcctg ctccgccccg atcggccgca
    12841 tcccgcggcc accgtcattc cgccggtaaa ccgagtatga ggagaagaac ccgaatgtac
    12901 gaaagagacc tgtccgcgac cgaagacgcc ctcggcgccg tgaacctgcc gcgcgccctc
    12961 gaggtcggct cgcgcaacca cgcgctggcg ggcagcaagc cgcggctgag cgccaacccg
    13021 ctcgccaccc tgtccagcga ccccggatcg ccgtccgtcg tcagtgtctt caccggcggc
    13081 tggatctgag acgggccacg aaggcgggca cgcgccgccc gccttcgtga tcagcttctc
    13141 gccgcgaaag gccgaaaccg ctcgctatag tcacggcggt gggaatccgt tcgtcgcggg
    13201 tgatcggccg tgacgccgaa ctgaccgagc tttccggagc tctcgatcgc gccatcgccg
    13261 gccgcggcgg cgcgatcttt ctcgtgggtg aaggcggcat cggcaagtcc cggctcgcca
    13321 tcgaagccgc ttcgcgagcg gtcaccgcgg acatcccggt cctgcagggc agggccggtt
    13381 cgatcggccc gctcgtcccg ttccggccac tgacccaggc attgtggtca cacttccgtg
    13441 gcggtggccc gcccgaggcg gccgaactcg acccgttcgt ccccgtcctc gcccagctcg
    13501 tccccgactg gagccaaggc gaccggcctc gggaatccgg ttccctgctc gtgctcgccg
    13561 aagcggtgtt ccggctgctg gccgtcacga gccgcggacg cggcgcgctg ctggtcctcg
    13621 acgacctcca agacgccgac gccgagacgc tgttcatcct cgaatacctc gtcgacaacc
    13681 tggcggcggc gcagaccctg ttcgtcggca cccttcgcaa cgagccctcg gacgccctcc
    13741 gcctggcgac caccggtgcc cagcggatga gctgcaccgt cctcgaactc gacaggctcg
    13801 gtctcgccga cacccgcgcc ctcgccgcgg cctgtctgga gaccgagccg ggacgcctgc
    13861 ccgcaccggc ggcggaactg ttgtggcgca acagcgccgg gctgccgttc atcgtcgagg
    13921 agctcctcca cggcatggtg aacgacggtc tgctggtgga gggcagggac ggctggcgcg
    13981 tcatcggaga gcttcgcgcc cgtgtacccg ccgcgctgat caccagtatc ggcgtccgga
    14041 tggagcaact cggcgagcag gcgggcgaac tgctgtcggt cgccgcgatc atcggacggc
    14101 gcttcccgct gccggtggtg cagagggtca ccgggacgaa cgaccggacc ttgcacaacc
    14161 acctcagcgc cgcggtctcg gcgaacctgg tgaccaccga cgagacgaca cccggctggt
    14221 acgccttccg ccatccgctg accgccgaag cgctgctcgc gcgtcagtca ccggcgcgga
    14281 aggcggcgct cgcccggcag gccgccgacg ccgtcgagaa gctgtaccca gggctgcccg
    14341 gtgatctgtg cgccctcgcc gcttcgctcc gcctgaccgc gctggacgag cgggcggcgg
    14401 gccacctttt cgccgaaacc ggtcgccgcg cgctcgacgc cggtgccgcg gactccgcgg
    14461 tcacgatgct caccaaggcc gtcgacctgc tcgccggggc cgacgcgggt gaccgggccg
    14521 aagtgctgga gacgctgctg tacgcgctcg ggcagaccgg ccagttcgac cgcgccgtcg
    14581 agctttccga cggattcggc gagatcggga cgctggaacg ggccgcgaaa ctgcacaccc
    14641 agctggcctg ggccgcctac atcgccggac ggcacgacga atgcctcggc cagatcgaac
    14701 gggcccgcgc tcccctcggc tcggcgatct cacctgccca gcaagcggcg ctcgacgccg
    14761 tcgaggcgaa tctctggctt gacgtccccg gccggaccgg caccgcggaa cggctcgcgc
    14821 ggcaggcgtg gaaggtggcc gaggagaccc ggcagccgtt cgtcgtctgc caggcgctcc
    14881 aggtgctcgg catgctcgcg ctgccgaggg atctcaccga gtccgagcac tacatgcagc
    14941 tcgcgcggcg gaccgccgag gacaaccacc tgcaccacct ccgcacccag gcgctggtcc
    15001 ggctcggcgg gcatcgcgtg ctgatgaacg gcgacgagca gaccctgctg ctcgcccgcg
    15061 acgacgccca gcggaccggg tcgatcacgc tgcactgcgc ggtcgattcc gtgcgcacca
    15121 tgcacgcgat cctgcgctgc gagttcgaca ccgcgcacgc gctgctggag gagaacctcg
    15181 ccgtgctcgg caggctccgg ttgaccgcgt tgctgcagta cgcgcatatg accagggcga
    15241 tgtcggccgg gcaccgggcg gaccgtccgg cgatggaaca ggcactcgcg gacttccggg
    15301 aaagcggcgg tgagaacgcg caggagatgg tgctgagcat cgggctggcg caggtctttt
    15361 gttcactgct cgaagaggac ttcgagcggg cgcgccgcga gctcgaccag gtgaccgagc
    15421 tcgaggaccg gcgaccgagc cgattccacc tcgccggcca gcacggactg aggacgctcg
    15481 tcgacacgct cggcggtgcc gactgccccg aggccggttc cgccatgagc gagatgcgat
    15541 ggaaccggca gttcgtcgag ttcgcgcacg ccgtcgagca cggcaggcga ggcgaggcgg
    15601 tggaagccgg gcaagccgtg acagccgcgc tggagacgtc ggcgccttat ccgctggccc
    15661 gctatctcgg gctccggctg atcgccgaac cggccgccgc cgacggctgg ggcgatccgg
    15721 cgggttggct caaggaagcc gaagagtact tccacggcag gggcatccag gctgtcgcgg
    15781 ccgcttgccg gagcctgctc cgcaagctcg gcgcgcccgt ccgccagcgc cgcgccgggg
    15841 tcgaccgcgt ccccggcgac ctgcgcgcgg caggcgtcac cgtgcgcgag tacgaggtgc
    15901 tggtgctgct cgccgagcga atgggcaaca aagacatcgg ggcccggctg cacatctccc
    15961 ccaggacggt cgagaagcac gtcgcgagct tgctcgccaa gaccggcctc gccgaccgct
    16021 cggccctcgc cgaacgagcg gccggaccgc gacctggcat gctgtgatcc atgaacgacc
    16081 tcaccgtgta cggcgccgtc tggtgccccg acgtcaaacg cagccgtgcc ttgctggacg
    16141 cgaagggcgt cgagtacgac tacgtcgatg tcgaagcgga caccggcgct gaagagatcg
    16201 tgcgagcgct gcagaacggt gagcggcgga tcccgaccat cgtctggccg gacggcaccc
    16261 acctggtcga accgagcgac gacgagctca ccgcgcatct gaaccgatga ccctcccgga
    16321 cgtcccggtc ggcacgaggg tcgtcgtgcg gtaccggatc gagggcgggt tcaccgacgc
    16381 gctcggctac ctgcgctccc gtgacgacgc ggaatgcacg gtggagacca aacgcggtct
    16441 cgccacgatc cggctggcag acatcgtcct ggcgaagacc gtcccaccac caccggcccc
    16501 acgcgggtcc cgtaaggaca cgttcggaag tccgtgaagg cctccttgag ggactctgag
    16561 tccctcaagg aggccttcac ggacttgcca cccggcacga cacgttgccg ctctaagtgg
    16621 ccttaccgct ggcaaggggt ttgtccagca ctgccttcac gtggctgaag ttgtcgatcg
    16681 agtagcggcc gtgatagcgg cccatgccgc tctcccccac cccgccgaac ggcagctcgg
    16741 gcgccgcgag gtggatgatc gccgccccga acaccagccc gccggacgac gtctccgtct
    16801 cgatcctgcg tttcgtttcg tccgattcgg tgaaggcgta caacgccagc ggcttgtcgc
    16861 gttcgttgac gaaggccagc gcggcgtcga cgtccgggac ctcgatgatc ggcaggatcg
    16921 ggccgaagat ctcgtcccgc atcaccggcg cgtccgggga gacgtcggtg agcacggtgg
    16981 gcgcgatgta cttctcgtcg cggtcggcct tgccgccgac gaccgcggtc ccgtcgtcca
    17041 gcagcgcggc gagccggtca tggtgccggg tcgagatgat ccggccgtag gagtcgctgg
    17101 tggccgggtc cgcgccgaac atcgcttcga cggtctcggc caggtgctcg gccagcttcg
    17161 ggccggtgtc gccgatcgcg aggacgtagt cgggcgcgac gcaggtctga cccgcgttgg
    17221 cgaacttgcc gtaggcgagc cgctgcgcgg tcacggcgag atccgcgccg ggctcgacga
    17281 tcgccgggct cttcccgccc agttcgagcg tgaccggtgt gagatgcttc gccgccgcgg
    17341 ccatgacgat ccggccgacg gtcccgttcc cggtgtagaa gatcgtgtcg aacttctgct
    17401 ccagcagcgc cgtcgtctcc gggatcgccc cctcgacgac gcggacgcct tcgacgtagg
    17461 ccggcagatg ctcggcgatc gcggccgagg tgttcgggga cagttcgctc ggcttcacga
    17521 ccgcgcagtt gcccgccgcc agcgccccga ccagcggcgc gagcaccagc tgcagcgggt
    17581 agttccacgg cccgatgatc agcgcgaccc cgagcggctc ccgcacgaca cgcccggcgc
    17641 caggccgcag gggctgtggg atatcggcgg gctccggggt cagccaagag tcgaggttct
    17701 ccagcgtgtg gtcgatctcg ttgcgcacga gcgcgatctc cgcgcgtttg gcctcgactg
    17761 cgttcttgcg caggtcggcg tagagcgcct tgatgaagac gtccgcctgc tcggtaagga
    17821 gcgcacgcag gcccgcgagc tgcttccgcc gccaggtcac cggcttcgtg acgccggagc
    17881 ggaacagttc gcgcaggtca ccgacgatcg cggaggcatc actgctgatc atggagccga
    17941 gcctaaccgc gcgacgcgcc gggcgcccga cgcgtcgcag tataggtcgt tatacagata
    18001 gctgaagggc gctttccccg catgtcatgc ggggaaagcg cccttcagcc cctcggtgct
    18061 acgggtagct caccaggttg ctcggcgtcg ttcccggtgg cgtcaccgct cccgcgtcgt
    18121 tgatcacgtg ggtgatggtc cccttgtagt tcagcgagac cgtcaccagg ttgtggaacc
    18181 ggacgccgga gcggttcggt acctcgaacg cgtgatacag gttcaccgcc gggttgtcgt
    18241 tgaagaagca gtagctgcca aggccccacg cctcgtgcgt ggtcacgttg tcccccacct
    18301 tgtaggctgc gtacccgttg agcccgttgg gactcttcca gcccgcctgg tccgggacgt
    18361 cgtaggggat ctcgttctgg aagaagatcg tcctgccgtt ctggccgttc cagatcacct
    18421 ggtacttctg gtagtgctcg acgaacaggc cggtcgccag cacgttgtcc ccgttgacga
    18481 cgacgccggt gtcgccggtg ttggccgtcc acccgtaggt gcccgcgttg ccgtggtcgg
    18541 cccgccaggc ccagatgtga tcgatgatcg tgtcccggct gttgacgatc aggctgttgg
    18601 tcgccttccc cgcgatctgg ccgccgatcc ggaagaacac gtcctgcagc gtcgtcgggt
    18661 tggccgagtg gttcgccgcc gagccggccg ggccgaccgt gagcagcgac tgcgagttgg
    18721 tcgttccggc gtcgaacagc aggcccttga gccggacccc gtccacgtcg gcgaccttca
    18781 tcgcgtcgac accgttgtcc ggcaccagcg tcgggtaccc gacgccgagg acgaccgtgt
    18841 tggccttggt cacgttcagc gtctggttga ggtggtagac gcctggagtg aagaacaggt
    18901 tgcagccctg ggaaagggcg ttgttgatcg acgacgccgt gtcccccgcc ttgacgacgt
    18961 agaactggct catcggcagc gaactgcccg gcgtgccacc gttggcccag ctcggcccgg
    19021 aagcgttggt gcgcaaggaa ggcaggaaca cgcggtactt accggagccg tccaggtaga
    19081 ggtacgggac gtcacgggac accggagtgg tgccgagtgt cgtctcgggc gggttcggga
    19141 acgtgttcgc cggggcgccg ttcgtcccgg agaacaccat gttccagacg ccgccctccc
    19201 agctgccgta gctgctgtcg cgggtgtacc actgctgctg cgagatcgac gcggtcttgc
    19261 ccgagacctt gctgtcggcg gtgtacccgc cgctggcgaa gccgtagctg gccgggaaga
    19321 ggttcaatcc cccgcggatg tccatccggc ggaacggcgc ggcctgcgcg acggcccagc
    19381 gggtcgcgcc gctgctcggc acgacggcca ggttctccgt cgagcgccag aagttctgca
    19441 gcgccacgcc cttgtccgac tcgttgaacg cgtcgacggt cacgtcgccg ttgatcacga
    19501 cgtcccctgg gttctgcccg agacccgcga cagaggtgta gtagccgacg tcgtcgtgga
    19561 tgccgttgta cacaccgggc ttgaacaggt gcgcgtaccg gcgttcggtg aactgcgcgg
    19621 tcagggtgtc cttctgcgcg ttgaagtccg cgtcgagctt ggcctggatc gacgacgccg
    19681 acataccggg gtcgaagatc cgcacgttgg gaccgaagtc cggcacctcg gcctgggcgg
    19741 ggcaggtcgc ctgcgtcgat ccgatcgtgt agctcgccga cgccacggcg gagttcgccg
    19801 agcccgattt gagcgcgatc gcggaaatcg tcgaagacgc ggagaccgtg atcggcccgg
    19861 tgtacacggt ggacgacgcg gtcggcgtgg atccgtccac tgtgtaccgg atggtcgcgc
    19921 ccgcggtcgc ggacgaaagt gtcaccgaac gggcactggg ataactgccg cccggcgggt
    19981 cgaacgtcgg tgaggcgacc gtggttccgc tgccgccgtg ggtgtagccg aagtgcgggg
    20041 tgtcgtactg cggcccgttc ttctcgtagg tgaaccagta gtcgagcacc gtgccggcgg
    20101 cgagcgaacc gacggtgtgc cgccacgttc ccccgctgtc ggtcatgcgg acgttctgct
    20161 ggcccacccc agggacgccg gtgtagtgga tgtcgacgta ccgcgcggtc gtcgccgggg
    20221 tgaaggagaa ctgcgcctgg gtcgcgttca aggacgcggc gctctggctg tagtccgcgg
    20281 cagcggcggt cgcgccgccg agaccggcgg cgatcaggag cgcggaaagg ccgagggcga
    20341 gcgcgccccg gacccctttc cgccgtttgg gctgcacaaa gatccggtcc acgtcgtgac
    20401 acctccggcg ttggaaatcc acgggcgaag caattcgttg cgcgccacaa caaagtaacg
    20461 gtccgtgaga tatgtccaga tcacgcttcg gtaacagtga tggtccaaac cacttgatgc
    20521 cccggacagc ccacgatgac acggccgttc ggcgtcatcg aatggtgcga tcgggcgctg
    20581 gtcagcagtc ggggacgacg tacagcgtcg aagcttcccc accgtgcatg gcgctcaggc
    20641 tggtccggca ggccaggagc acctcgcgat tcgcggccgt gtccggcggg acgccacagc
    20701 cgtcgcacga gagctcgacc gaaccaggaa aggtctcgtc gacctcgacg tcgaccgtgc
    20761 gatcgcagcg acggcaccac cggtgcccgg tgacgatcag gacgtgcatc ggatcggaga
    20821 cacactgatg cacccagcaa cggtggacgt aacaggtcgt ccggacgtgc gcgctcagcc
    20881 cgtgttcctc ggcgacgtct tccgcggcga ggatcgcggc cagccgccgg tcggcgattt
    20941 cggcgtagag gtcccggcgc cgggccgggg gtgccgcgtc cgcttccgcg agcagtctga
    21001 gatgagccct tgagggtggc gaagtacgaa gcaccatgtg ggtctcaacc tttcggcgtc
    21061 caccggaagt cttatcaggt cacttccgat ttcgccggag cgacacccga ccgggcgaca
    21121 acgaccgtcc cgtttgtacg gcccttgtac tcgcgctgct catgctggcc ggacatcggg
    21181 tcgaagttcg ttcaggaggc aggaattgtt gaccaaggta gccgtcgtcg cgacagcgac
    21241 cgcgctctcc ttcggcgtgg ccgcaccggc cagtgccgaa gtggccgcgg ccgcgttgcc
    21301 cgcggccagt atggaagcgg tgctcaaagc cgcgcagatc gacccgcgcc gggccgacag
    21361 cgccttgact ccgggcgcca aggacagtgt cctgctggtg gagcaggccc tgtccgccaa
    21421 gggattgctc gaccagcagt acgtcgacgg ccatttcggc acgtcgacga tcaccgcgta
    21481 ttcgagctac cagaagtcgc tgggctacac cgggatcgac gcttccggac tgccgggcaa
    21541 gacgtcgctc gagaagctgg gcgagggccg gtacaccgtg accgcgacgg tcgcggcggg
    21601 tagccgtctc acctaccacg gcgagacgat gaacacccgc accaaggcga tgctggtgaa
    21661 ggcggaaggc ctgctcggca ggcagctcac catcacgcag ggctcgtaca accccggcgg
    21721 cgtcggcgct tcggccggga cgcacgacgg cggcggcgcg ctcgacatcg gcgtcgaagg
    21781 catgtcctcg gccacgcgga ccgacgtcgc gcggaagctg cgtcaggtgg gcttcgcggc
    21841 ttgggtccgg accccggccc agggcttcgc ctaccacatc cacgccatcg cactgtccga
    21901 tccggacctg tcgtccggcg cgcagcacca ggccggtgac tactacctcg ggtacaacgg
    21961 cctcgccggc cgcggctccg acgacggtcc cgccgtctcg ccgaagctca cgtgggagga
    22021 gtaccagcga ggctgacccc tccgctcaaa ggccaccttc gcgacgcgaa ggtggccttc
    22081 gggctgtccg ggaaccccac gggtaggctt cggcgcgacg gcaaaacgag cgggaaggga
    22141 acatcgcgtg gaggatcgac cggtcggtca gtggctcgat gagctggctt cgaaggcctc
    22201 gacgcccggt ggtggcgcgg gtgccgcgat gaacgccgcc gtgggtgccg ccctcgtctc
    22261 catggtgtgc aacctgacca tcggcaagcc gaagtacgcc gagcacgagg ccaccatgac
    22321 cgaggcgctg gccaaggccg aggacctccg cggccgcgcg ctcggcctcg ccgccgaaga
    22381 cgccgccgcg ttcgaagcgg tggtcgccgc gtacaagctc ccgaaggcca ccgacgagga
    22441 gaagcaggcc cgcacggccg cgatccaggc cgccctggtc ggcgccgccg aggtcccgct
    22501 gcgcacggcc gccctcgccg ccgaggtcat cgacgtcgcg gcttcgatcc tcgaaggcgc
    22561 caacaccaac gtcatctccg acatcgcggt cgccgcctcc tccgccaagt ccgcgctcga
    22621 gtcgggcgtg gtcaacgtcg aggtcaacct cgcgtcgatg tcggacgagc agctccgcaa
    22681 ggagaccgag gcccggctcg ccgagtacac gcccgccgcc gggcgcgccg acgtcctcat
    22741 cgcccaggtt cgcgaaaggc tcgcccgatg accctgatcg acgggcgcgc gatcgccgcc
    22801 gccatcaccg ccgaggtcac cgagaccgcc gccaagctgc gcgaatccgg caccgcgccg
    22861 acgctggccg tgctcgtgcc
//
