LOCUS       NZ_KB913032            21026 bp    DNA     linear   CON 28-APR-2024
DEFINITION  Amycolatopsis alba DSM 44262 scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_KB913032
VERSION     NZ_KB913032.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Amycolatopsis alba DSM 44262
  ORGANISM  Amycolatopsis alba DSM 44262
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 9811274)
  AUTHORS   Klenk,H.-P., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Amycolatopsis alba DSM 44262
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: India
            num_replicons                     :: Missing
            ref_biomaterial                   :: DSM 44262
            biotic_relationship               :: Free living
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.05; ALLPATHS v. r41043; Phrap v. 4.24
            finishing_strategy                :: Missing
            environment                       :: Soil
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi10729
            Current Finishing Status          :: Level 2: High-Quality Draft
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2011
            Isolation Site                    :: Soil
            Cell Shape                        :: Filament-shaped
            Motility                          :: Nonmotile
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Gram Staining                     :: Gram+
            Diseases                          :: None
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.05; ALLPATHS v. r41043; Phrap v.
            4.24
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina GAii
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000384215.1-RS_2024_04_28
            Annotation Date                   :: 04/28/2024 01:36:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,988
            CDSs (total)                      :: 8,922
            Genes (coding)                    :: 8,855
            CDSs (with protein)               :: 8,855
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 24 of 67
            Pseudo Genes (incomplete)         :: 49 of 67
            Pseudo Genes (internal stop)      :: 4 of 67
            Pseudo Genes (multiple problems)  :: 10 of 67
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:42:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5551337
            Orig. end                         :: 5572363
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB913032.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 404842
            Source DNA and Organism available from Hans-Peter  Klenk
            (hpk@dsmz.de)
            Source DNA available from Hans-Peter  Klenk (hpk@dsmz.de)
            Organism available from Hans-Peter  Klenk (hpk@dsmz.de)
            Contacts: Hans-Peter  Klenk (hpk@dsmz.de)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21026
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="20"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21026
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21026
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11026](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11026)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            357..680
                     /locus_tag="AMYAL_RS0126330"
     CDS             357..680
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153148.1"
                     /locus_tag="AMYAL_RS0126330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator"
                     /protein_id="WP_020634259.1"
                     /transl_table=11
                     /translation="MSEDGLPQLDPVIHAQARLRVTVALSSLGPGDRITFPRLQQLLDM
                     TPGNLSTHLRKLEDAGYVEITKAFEHRTPVTLVELTTRGRAAFEEYTKALHRLLEVPGD
                     GRA"
     gene            667..1983
                     /locus_tag="AMYAL_RS0126335"
     CDS             667..1983
                     /EC_number="2.7.7.7"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332005.1"
                     /locus_tag="AMYAL_RS0126335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA polymerase IV"
                     /protein_id="WP_020634260.1"
                     /transl_table=11
                     /translation="MGGHDRWVIHLDMDAFYASCEQLTRPTLARRPVLVGGAGPRGVVA
                     GASYQAREHGIKSAMPMSQARRLLPPNGVILPPRFKLYELLSTQVFDLVAQYAPVLERI
                     SLDEAFAEPPSLAGASSDQVREFGARLREHIRSDIGLVASIGAASGKQVAKVASDLAKP
                     DGLLVVDQGTERDFLAPLPTRVLWGIGPVAEGKLRAIGVRTLGQLTALSDADAVSTLGS
                     VVGRDLRRLATGVDDRPVSDRAELKQVSAETTFDRDLIDLPSLRREVRDLAVHAHKRLV
                     NAGRVARTVVVKLRHTDFSTVTRSETMASPTDEFDQLASMAERLLIDPTEFGGVRLAGV
                     AFSGLSVPHQDPLFTLAVPAPDVPVVERAPAPVVAVSSTWRPGDDVVHDAHGTGWVQGA
                     GHGRVTVRFETRSSGPGVARTFPQEDPALRRGEPGDCLV"
     gene            2086..2934
                     /locus_tag="AMYAL_RS47835"
     CDS             2086..2934
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMYAL_RS47835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143267604.1"
                     /transl_table=11
                     /translation="MATHSSVPMLLDRRRMFYLATVGGLVVALAAGVMLCLGLSGDGAA
                     WVRSAELVVLSAGLLAAGIACGIALQYGRKVRGATVDTWLPVETAVARKPGLEVQSQRF
                     HTMSLLAIPLSIFLVVMFGLMVWLSVVVVRSPALAILPGVPLAVGGFGSLTAWAGWNRR
                     ARSVRKTGWYAAKVVDVEVFEGRAAPLPLISIGFEDGSTIRLRSIMSTYDARYQAGRRN
                     AEAWVGGEDTAMVVLFENGAFRKGLYPVPVKALGPRTFPPSSTPPRDRAGSPSWVKRVG
                     R"
     gene            complement(2931..4010)
                     /locus_tag="AMYAL_RS0126345"
     CDS             complement(2931..4010)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223411.1"
                     /locus_tag="AMYAL_RS0126345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="WP_020634262.1"
                     /transl_table=11
                     /translation="MIGWTSAGQGRGRVALLAAAVLGASLSTVPPAVAAEQCTVAKAMI
                     AAGDHWVANGTDLAANSWQNGTFHVGNLALVRTTGVSNHKTLPWAQDNKYLLQSDPARP
                     FFPAFQAAGEAYLDLYSFHPDAPVIADVRQRIADEVVSVERGNTGYWDHVEALNMAMPS
                     LARIGVMDGSEPALAAMGKLFRSAERKLYDGGIGLWRRDAGSDAYWSRGNGWALAGLAK
                     VLQVLPSGDPRRPEYLRVFEKMANTLWFLQRRDGFWNTDLLRPWNHGGPESSGTALITF
                     GLAWGVNAGLLDAGKYRRTVDKAWEALSTKALRADGFLGYVQPVASGPGPSSAGDTGAY
                     GVGAFLIAGQQVARLTPGC"
     gene            complement(4269..4916)
                     /locus_tag="AMYAL_RS0126350"
     CDS             complement(4269..4916)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153142.1"
                     /locus_tag="AMYAL_RS0126350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FCD domain-containing protein"
                     /protein_id="WP_020634263.1"
                     /transl_table=11
                     /translation="MTRHARIVDELGRLIVSGAFGTEQPIVPEDLGRRFSASRTVVREA
                     LRVLESKGMVAARPRVGTWTRPPEHWDAIDPDVIAWRVAGPERSRHLAELHELRLAIEP
                     QAARMAAWHRCPDELAVLVATYGLMADAVDLRAFQEADRAFHAALLRASGNALIAQLHI
                     PVVAALEEVPGDEVLSAHSLVVAAVLGKDGDGAESASRRLLETVVPYRSPAS"
     misc_feature    complement(4308..4310)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4913..5950)
                     /locus_tag="AMYAL_RS0126355"
     CDS             complement(4913..5950)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153140.1"
                     /locus_tag="AMYAL_RS0126355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_020634264.1"
                     /transl_table=11
                     /translation="MSTPTRTESEERAPAAEAERVSPVRRVLTAIGVQNSSLLLTLIAL
                     VILMSSLNENFLRTNNLLLIGSAITIMGLLSLVQTLVIILGALDISVGSMAGLASVVSA
                     MVFTSTGSSAVGTLAAIGVGVVCGLVNGMIIIFGRVNPVVATLAMLATYKGIAQVVSDG
                     KAQGYTGADDLFIFLAKGSIAGLPTLVWVFLLVAAILHFLLRYTDIGRNIYAIGGNDTA
                     ARLAGININRYIIGVYALVGVVAAIAGLLITARTGSGQPTSGSEGLELLAVTGAALGGT
                     MLKGGKGSIISTVLAVIILGVLNNGMSGLGVNPFWQNMATGTLLVVAVVLQQVRGGERR
                     VGLPV"
     gene            complement(5947..7479)
                     /locus_tag="AMYAL_RS0126360"
     CDS             complement(5947..7479)
                     /EC_number="7.5.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153137.1"
                     /locus_tag="AMYAL_RS0126360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="WP_020634265.1"
                     /transl_table=11
                     /translation="MATSEPAAALTAEGISKRFSGVTALDGVTLDFRPGEVLALMGENG
                     AGKSTLLRVLSGDHGPDDGRLLLDGGPMTFDSPRAAMAAGIRVIYQEPEIIPHVSVAEN
                     VFVGELPTRGRLVNRRTLHRMTQEALREYGFEGVLRPETLGSRLSAAQRQLVEILRVLT
                     ATTTAKVIAFDEPTSSLSEHEVDALFALIRRLRDSGVAVVYVSHRMKEIFQLADRVAVL
                     RDGRLIGVEDAASTDENRLVRMMIGRDLSTLERRVTQETGRVVLRLDQVTTDDVADISL
                     EVRAGEVVCLAGLVGAGRSELAHAIVGDLPVRSGTVELDGKPLRARTPGDAVKAGIGFA
                     PEERKTDALLMQRSVRDNVSIAVLDRLRRFRVVRRAKERELVEEYVRELRVRTPSMEQE
                     VRKLSGGNQQKTVLARWLARRPKLLILDEPTRGVDVGAKAEIYRIIDGLAAEGIALLVI
                     SSDLPEVLSLADRIVVLRAGRVAGELGRDDASEEAVLTLAIPATEEDLEIVS"
     misc_feature    complement(6508..6510)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7500..8471)
                     /locus_tag="AMYAL_RS0126365"
     CDS             complement(7500..8471)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153135.1"
                     /locus_tag="AMYAL_RS0126365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_245193052.1"
                     /transl_table=11
                     /translation="MTGCSSGKETATPQQQAPASGKVTLFYLQKQGDQQYFVEQAQGAQ
                     EKAKELGVELKVVNLGQDANKAITELDAALAQGANGIAIVVPDQAIGPQVLDKAKSAGI
                     PIIASDDVIKDGGGTKSPFVGFNGSQMGDSVGKEAAKLFKAAGWTAADTKIISAYKQDL
                     TVCSDRVSAAKAAFDKTLSDQKSGAQVPVIEVGTDNTPVDAQNRTGAVIGSNPGVKHWV
                     VWGCNDENETGAVTALANSGVPAADIIGVGLGAYLTCKDWAAGKDTGNKSALFISGAEV
                     GRTAIGLLVDKVKNSKELPPETIAKTQIVTKDNYKQAGVNCI"
     misc_feature    complement(8731..8749)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.13"
                     /tool="antismash"
     gene            8798..9928
                     /locus_tag="AMYAL_RS0126370"
     CDS             8798..9928
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034061.1"
                     /locus_tag="AMYAL_RS0126370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CapA family protein"
                     /protein_id="WP_020634267.1"
                     /transl_table=11
                     /translation="MFSSRARQGTALLATALLLAACSTTSEEPKPPAASEAPTQASQAP
                     DGSFTVVATGDVLIHPALTDQAKEDGKGEIDYRPLLAGIKPLISGADLGICHLETPLAP
                     KGGPYSGYPSFSAPPEIVDALKDTGYDNCSTASNHTIDQGADGATRTLDKLDEAGIKHT
                     GSARSAEEAKKPLIVDVKGVKVAQISFAYGFNGIKVPAGKPWLVNQIDAEDVIAQAKAA
                     RKAGAQVVVASLHWGTEYQHEATAEQRSLAKKLLGDDSIDLIIGHHAHVVQPFEQINGK
                     WVAYGLGNSVARHSEPKGSTEQGAAARFRFVRDGERWKVDKAEYVPTLVQLGPPIRLLD
                     LTAGQAGNAGAEALKATDEVVLSRGAGERGLTRLGR"
     gene            complement(10001..11026)
                     /locus_tag="AMYAL_RS0126375"
     CDS             complement(10001..11026)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034060.1"
                     /locus_tag="AMYAL_RS0126375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_020634268.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.5e-64, bitscore:
                     215.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTIDTRIGSRPANEVLAWSRNLLDPALREAVDGLPESMRLIAGY
                     HFGWWDEHGRPSTSDGGKALRPALALLSAQAVGGDAEVAVPVGVAVEMVHNFSLLHDDV
                     MDRDTTRRHRPTAWTIFGTGAAILAGDALLCRAFEMLAPFGQTALRVLSTAVIELLEGQ
                     SADLKFEERGDVDTAECVRMAEGKTGALLGASCTLGAIAGEGRQDQVDRLTEYGRALGL
                     AFQHIDDLLGIWGDPAVTGKPVHSDLSNRKKSLPVVAALHSGTEAGRELDALYRKENLE
                     AAELPHAAELVERAGGRSWSQEQADALLTGALHHLAVSNPVPRPGAELAALAKLVVRRR
                     Y"
     misc_feature    11308..11324
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.41"
                     /tool="antismash"
     misc_feature    11338..11352
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.58"
                     /tool="antismash"
     gene            11476..12240
                     /locus_tag="AMYAL_RS0126380"
     CDS             11476..12240
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153131.1"
                     /locus_tag="AMYAL_RS0126380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4239 domain-containing protein"
                     /protein_id="WP_020634269.1"
                     /transl_table=11
                     /translation="MGIYLTGIAWVVGAAAFAGFVGYLVRKFGWDEGRPDNNDAAGQVF
                     TIVGGLHAVLVAFILISLFDSASAARDGSYHEADSLVAAVWAADSLGDEVKVEVRKLSA
                     EYISTVEKKEWPQMAGGEETVSGAGWTQLDQLRKAVDKAPSDDDWFRERKTEASTQLWQ
                     VYEARQARLNAVEGGKVGGVVWFALILGSLISVLLPNLFGGTRLAAHLVIVSTLAGTVT
                     LLLFAIYQLQNPFGGGVRIPPDAFTAALARLT"
     gene            12245..13510
                     /locus_tag="AMYAL_RS0126385"
     CDS             12245..13510
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034058.1"
                     /locus_tag="AMYAL_RS0126385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_026467462.1"
                     /transl_table=11
                     /translation="MSTVDGVTRAAATAAVAGLVGASALLAPMTARAAESCLVVQAETG
                     SYGTSKLRWLDVGSGTTSRVTEPGYRLNALGYSATRDLVFGVAEGLSRGAHAVSIDRDG
                     RTEDLGPITRAGNRLPLWSPVAGVTAGAIGGNSWYLLRNGTLYTVDLTPGERYLRVIRT
                     VFLRPITLAHDVNDFAYHNGLLYGVSTTWRGRGAVITIDPASGKVREVEDARFPPADIY
                     GSVVLARDGALYATANRIGGRSVLYRLDRGGQVTEVLSGPPLAGSDAAGCLTAPEPPEP
                     EPPKPTPTPTPSPTPTPTPSPTPTPSPSPSPTPSPNPSPSPSPTPSPSPTPSPSPAPSP
                     TPTSSPRPSPTPSPTPTSMAKVIPPPAPVPKPSRAAAPKQEKAAAKADPHARTKEKRRW
                     GLTALVLILGGGAAAGAVRRAR"
     gene            complement(13512..14528)
                     /locus_tag="AMYAL_RS0126390"
     CDS             complement(13512..14528)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003072072.1"
                     /locus_tag="AMYAL_RS0126390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_020634270.1"
                     /transl_table=11
                     /translation="MRGPTKTLVVAAVLAWGMVFGLTGCGGDAPAEVTAKPIRIAFVPK
                     VAGIPYFEAMNTGGHDAAKQLGVEWTSTGPATVDPAAQVSIMRGLVDQRVDVIAIAPND
                     PRAIAPAITDARAKGVHVITSDTDAPGTDRELFVNQATPEGIGKALTDALMKKMGGAGK
                     YAIVSCGETAENLNAWIAVQRAYTATEYPHAQLVETVYAGEDKEYATALAKDLMRKYPD
                     LTGLVGECTTSAPGVAEAVRSQQKIGRVFTVGVGTPTAIKPYLLDGSASLSVLWNVESL
                     GYLTAWAGKQIAEGKPLGPSNKVNLELPAIKYEADRKTVLLGDPLLITRENVDQFKY"
     misc_feature    14739..14754
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            14766..15224
                     /locus_tag="AMYAL_RS0126395"
     CDS             14766..15224
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466680.1"
                     /locus_tag="AMYAL_RS0126395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4396 domain-containing protein"
                     /protein_id="WP_026467464.1"
                     /transl_table=11
                     /translation="MNETRHGASWSMAASATLHCLTGCAIGEVLGMVIGTALGLHNAGT
                     IVLSIALAFVFGYALTMRGVLKSGLAFGAALKVALAADTVSIAVMEIVDNGVMVVVPGA
                     MDAGLGSLLFWGALAFSLAVAFVLTVPVNKWMIGRGLGHAKVHAHHAH"
     gene            complement(15255..15527)
                     /locus_tag="AMYAL_RS50410"
     CDS             complement(15255..15527)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMYAL_RS50410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_020634272.1"
                     /transl_table=11
                     /translation="MACGLLDLAKAANRPQYREAAIRILTALCDTCLTTKSARAEAIVA
                     RGTRNRPAEDGVEVSLPYGDYYLLEGILRVLMPKEIDKAIGLSAV"
     gene            complement(15579..16451)
                     /locus_tag="AMYAL_RS46210"
     CDS             complement(15579..16451)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019113.4"
                     /locus_tag="AMYAL_RS46210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="WP_245193054.1"
                     /transl_table=11
                     /translation="MTTAAGAAVAATAITPAATAATEEADGLRTFRRTADYAVAKLRAV
                     APGVTTFPEITRFEKWTYSAKGGWIGGFWPGTLWLASIYSGDPQFRALAAASAEKLAPR
                     QYETSDHDLGFLFYPSWVTGWRLTGDGKWRTGALNAAASLIQRYNEKGKFIRAWGALGT
                     PGNAGRVIVDTMMNLDLLTFASEQTGDRKYLDIAVSHAKTTERVFVRPDGSTPHVFDFD
                     PDTGAEIGPNSVQGYGPASCWSRGQAWAIYGFTTMYRRSGDPLFLRTAQRLADFALRAL
                     TPDNVPVWD"
     misc_feature    complement(16571..16584)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.95"
                     /tool="antismash"
     gene            complement(16713..17945)
                     /locus_tag="AMYAL_RS0126405"
     CDS             complement(16713..17945)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223425.1"
                     /locus_tag="AMYAL_RS0126405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_020634274.1"
                     /transl_table=11
                     /translation="MVRTVKARRVMAAVLAVLASGAVTALAPSPANAAPEGSWRADLST
                     VDGDDVNVRSDGGVLSLENAAWHRKPDSIGSQGYLLLAEQQLGKPVNRVTAQVTADAPK
                     GTEVEVDVRGKLNSNDWTEWTPTEGGAAQLSTSVSTVQVRIGLRTLTDGVTAKVSDVTL
                     QGELGPQVNAIGAAAAPLTYKVFGTREGLVGGTTANGHVIKSRDHFVALPSGRGLAPKN
                     TGNYTVRICRTDNSRCEYAPVWDVGPWNTKDDYWNPSATRQMWKNLPQGKPEAQAAYQD
                     GYNGGKDEFGRKPANPAGIDLADGTFWDGLKMTDNGWVNVSYLWIGSGPTGVVSTAGDP
                     MNVRASASTSAAIKGLAANYAKVNIECYVEGDTVTGKFGTSNIWDRIGPGHYISDTYLQ
                     TGSDLPVAPKC"
     misc_feature    20332..20346
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(20667..20681)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
ORIGIN
        1 cgcgcgggcc gtggcgtgcg cggaccgtcc cgactcgtcg gggcgatgta cgggtggagc
       61 tgggtgatcg cgttcggcgg gctgacggtg gtgaacaccg cgctgatccg cctcggcctc
      121 gacaccgacc tgatcccgtt gctgtggtcc gggacgtcgc tcatgctgac cggcctgatg
      181 tacctcgcgg gcggaatgct gtggcagagc aaactgcagt acggcctcgg cgtgtggatc
      241 atcgcgtgcg gcgcggcgag tgtgctggcg ggcgggccgc acaacttcct cgtgctgagc
      301 ctcgcgggcg gcggtggctt cctggtggcg tcgctggtct tcctggtgcg gtcgcgatga
      361 gcgaagacgg gctgccgcag ctcgatccgg tgatccacgc gcaggcgcgg ttgcgggtca
      421 cggtggcgct gtcgagcctc gggccggggg atcgcatcac tttcccgcgg ctacagcagc
      481 tgctggacat gacaccgggc aatctgtcga cgcatctgcg caaactcgag gacgccggct
      541 acgtcgagat caccaaggcc ttcgaacatc gcacaccggt cacgctggtc gagctgacca
      601 cccgtggccg ggccgcgttc gaggagtaca cgaaggccct gcaccgtctt ctcgaggtac
      661 cgggcgatgg gcgggcatga ccggtgggtc atccatctcg acatggacgc gttctacgcc
      721 tcctgtgaac agctgacccg gccgaccctg gcgcggcgtc ccgtcctggt cggcggcgcg
      781 ggcccgcgcg gcgtggtcgc cggggcgagt taccaggcgc gtgaacacgg gatcaagtcg
      841 gcgatgccga tgtcgcaggc ccgacggctg ctgccgccca acggcgtgat cctcccgccg
      901 cggttcaagt tgtacgaact gctgagcacg caggtgttcg atcttgtcgc ccagtacgcg
      961 cccgtgctgg aacggatctc cctcgacgag gccttcgcgg aaccgccgtc gctggccggg
     1021 gcgtcgtcgg atcaggtccg ggagttcggt gcccgcctgc gggaacacat ccggtccgac
     1081 atcggcctgg tggcgtcgat cggggcggcg tcggggaagc aggtggcgaa ggtcgcgtcg
     1141 gatctggcca aaccggacgg gctgctcgtc gtcgaccagg gcaccgaacg cgacttcctc
     1201 gccccgttgc cgaccagggt gctgtggggg atcggcccgg tggcggaggg gaaactgcgg
     1261 gcgatcggcg tccggacgct cgggcagctc accgcgctct ccgacgccga cgcggtgtcc
     1321 actttgggca gtgtggtcgg ccgggacctg cggcgcctgg cgaccggcgt cgacgaccgg
     1381 ccggtgtccg accgcgcgga actcaagcag gtcagcgcgg agacgacctt cgaccgggac
     1441 ctgatcgacc tgccgagcct gcggcgcgag gtccgcgacc tcgccgtcca cgcgcacaaa
     1501 cggctcgtca acgccggcag ggtcgcgcgg acggtggtgg tgaaactgcg gcacaccgac
     1561 ttcagcacgg tgacacgttc ggagacgatg gcctcaccca ccgacgaatt cgaccagctc
     1621 gcctcgatgg cggaacggct gctgatcgac ccgaccgaat tcggcggggt gcggctggcc
     1681 ggggtcgcgt tctcggggct ttcggtgccg catcaggatc cgctgttcac gctcgccgtc
     1741 cctgctccgg acgtgcccgt ggtcgagcgg gcgcccgcac cggtggtcgc ggtctcgtcg
     1801 acttggcgcc ccggagacga cgtcgtgcac gatgcgcacg gaacgggctg ggtgcagggc
     1861 gccgggcacg ggcgggtgac cgtgcggttc gagacgcggt ccagcggccc tggtgtggcg
     1921 cggaccttcc ctcaggagga tccggctctg cgccgaggcg aacccggcga ctgcctggtc
     1981 tgatcccgaa acgcgttccg atcgtgaggc ggttcgggta tcgtccaggt aggagcgccg
     2041 ggaagtctgg tcggcatggt gttcgtcgac ccaagggagt tccccgtggc cacccattct
     2101 tcagtgccga tgcttctgga ccggcgacgg atgttctacc tggcgaccgt gggcgggctc
     2161 gtggtcgccc ttgccgccgg cgtcatgctt tgcctcggtc tgtcagggga cggcgccgcc
     2221 tgggtgagaa gcgccgaact cgtggtcctg tcggccgggc tcctcgccgc cgggatcgcg
     2281 tgcggcatcg ctctccagta cggccgcaag gtacgcgggg ccacggtcga cacctggctt
     2341 cccgtggaaa cagccgtcgc acggaagcca ggactcgagg tgcaatccca gcgtttccac
     2401 accatgagcc tcctggccat cccgctctcc atattccttg tcgtgatgtt cggtctcatg
     2461 gtgtggctct cggtggtggt ggtgcgttca ccggccctcg cgattctccc cggcgttcca
     2521 ctggccgtcg gaggcttcgg cagcttgaca gcctgggcgg gctggaacag aagagccagg
     2581 tccgtgcgga agaccggttg gtacgccgcg aaagtcgtcg acgtcgaagt cttcgaagga
     2641 cgtgcggcgc ccctgccgtt gatctcgatc ggcttcgaag acggcagcac gatccggctc
     2701 cgttcgatca tgtcgaccta cgacgccagg tatcaggcgg gacgccgcaa tgccgaggcg
     2761 tgggtcggcg gcgaagacac cgccatggtc gtcttgttcg aaaacggcgc cttccggaaa
     2821 ggcctgtatc cggtaccggt gaaggccctc ggcccacgta ctttcccgcc gagttcgacg
     2881 ccccctcgtg accgggcagg cagtccgagc tgggtcaagc gggtcgggcg ctagcagccg
     2941 ggcgtcaggc gggccacctg ctgtcccgcg atcaggaacg cgccgacgcc gtaggcaccc
     3001 gtgtcaccgg cactcgaagg cccagggccg gaagcgaccg gctgcacgta gccgaggaaa
     3061 ccgtccgccc gcaaagcctt ggtggacaac gcttcccagg ccttgtcgac ggtgcgccgg
     3121 tacttgcccg cgtcgaggag cccggcgttg acgccccagg cgagcccgaa cgtgatcagc
     3181 gcggtcccgc tgctttccgg tccgccgtgg ttccacggcc gcagcagatc cgtgttccag
     3241 aagccgtccc gtcgctgcag gaaccagagc gtgttcgcca tcttctcgaa gacccgcagg
     3301 tactccggcc gacgcgggtc gccggaaggc aggacctgca gcaccttcgc caaaccggcg
     3361 agcgcccagc cgttgccgcg cgaccagtaa gcgtcgctgc ccgcgtcgcg gcgccagagt
     3421 ccgatcccgc cgtcgtacag cttcctttcc gccgagcgga acagtttccc catcgccgcc
     3481 agtgccggct cgctgccgtc catgacgccg atccgcgcca gcgacggcat cgccatgttc
     3541 agcgcctcga cgtggtccca gtaaccggta ttgccccgct ccacactcac gacctcgtcg
     3601 gcgatccgtt ggcggacatc ggcgatcacc ggggcgtcgg ggtggaagga gtacaggtcc
     3661 agatacgcct caccggccgc ctggaaggcc gggaagaacg gccgcgccgg gtcgctctgc
     3721 aacaggtact tgttgtcctg ggcccacgga agcgtcttgt ggttcgagac gcccgtcgtc
     3781 cgcaccagcg cgaggttccc gacgtggaag gtgccgttct gccatgagtt cgccgcgaga
     3841 tccgttccgt tggcgaccca gtggtcgcct gccgcgatca tcgccttcgc cacggtgcac
     3901 tgctccgcgg cgacggccgg gggcacggtc gacaggctcg cgcccaacac cgccgcggcg
     3961 agcagggcga cccggcctcg cccttgtccg gctgacgtcc acccgatcac gcgtctcgtc
     4021 catccaatca cgagagttcg ccgtctgatc acgcgagttc gccgatgccg caagccgggc
     4081 cggcgtgact ggatggacga cacgcgtgat cagacggacg acacgcgtga ttgagcggcg
     4141 atctcgcggg ggccgcatgg ccgattccga ggaaacgcat ggagcgtcct ccttaagcac
     4201 ttcgcggcgg cggtgagctt ccgtgcccgg aaacccggaa tcgagaatgg tgtgcaccgc
     4261 tgagggtgtc aagatgccgg tgagcggtac ggcacaacgg tttccagtaa ccggcgcgac
     4321 gccgattccg ctccgtcacc gtcttttccg agcaccgccg cgaccacgag cgaatgggcg
     4381 gacagcactt cgtcgccggg cacctcttcg agcgccgcga cgaccggaat gtgcaactgc
     4441 gcgatcaaag cgttgccgga cgcgcgaagc agggccgcgt ggaaggcgcg gtcggcctcc
     4501 tgaaaagccc ggaggtcgac cgcgtcggcc atcagcccgt acgtcgcgac gaggaccgcg
     4561 agctcgtccg gacaccgatg ccacgcggcc atccgcgccg cctgcggttc gatcgccagc
     4621 cgcagttcgt gcagttccgc cagatgccgc gagcgttcgg gaccggcgac ccgccacgcg
     4681 atgacgtcgg gatcgatcgc gtcccagtgc tccggcggcc gcgtccaggt gccgacccgc
     4741 ggtcgcgccg cgaccatgcc cttggattcc agcacccgca acgcttcccg caccaccgtg
     4801 cgcgacgcgg agaaccggcg gccgagatcc tccggcacga tcggctgctc ggtcccgaag
     4861 gccccggaaa cgatcagcct gcccagttcg tcgacgatcc gggcatgtcg ggtcatacgg
     4921 gcaggccgac ccggcgttcc ccgccgcgga cctgctggag cacgacggcg acgacgagca
     4981 gggtcccggt ggccatgttc tgccagaagg ggttgacgcc gagcccggac atcccgttgt
     5041 tgagcacgcc caggatgatc accgccagca cggtgctgat gatggatccc ttgccgccct
     5101 tgagcatcgt gccgccgagc gcggcgccgg tgacggcgag cagttcgagc ccttcggaac
     5161 cggatgtcgg ctgccctgat ccggtgcgcg cggtgatcag cagccccgcg atcgccgcga
     5221 ccactccgac gagggcgtac acgccgatga tgtagcggtt gatgttgatc ccggccagcc
     5281 gcgcggcggt gtcgttgccg ccgatcgcgt agatgttgcg gccgatgtcg gtgtagcgca
     5341 acaggaagtg caggatcgcc gcgacgagca ggaacaccca caccagcgtc ggcagtccgg
     5401 cgatggagcc cttggccagg aagatgaaca ggtcgtcggc gccggtgtag ccctgcgcct
     5461 tcccgtccga gaccacctgc gcgatgccct tgtacgtcgc cagcatcgcc agcgtcgcga
     5521 ccaccgggtt gacccggccg aagatgatga tcatgccgtt gaccaggccg cacaccacgc
     5581 cgacgccgat cgcggcgagc gtcccgaccg cggaggagcc ggtcgaggtg aacaccatcg
     5641 ccgaaaccac cgacgcgagc ccggccatcg agccgaccga gatgtccagc gcgcccagga
     5701 tgatcaccag ggtctgcacc agcgacaaca ggcccatgat ggtgatcgcg ctgccgatca
     5761 ggagcaggtt gttggtgcgg aggaagttct cgttcagcga gctcatcagg atcaccagcg
     5821 cgatcagggt gagcagcagg ctcgagttct gcacgccgat cgcggtcagc acccggcgga
     5881 cgggggagac acgctcggct tccgcggcgg gagcccgttc ttcggattcg gtgcgcgtgg
     5941 gggtgctcac gagacgatct ccaggtcttc ttcggtggcg ggaatggcca gggtcagcac
     6001 ggcttcttca ctcgcgtcgt cgcggccgag ctcgcccgcg acccggcccg cgcgcagcac
     6061 gacgatccgg tcggcgagac tcagcacctc gggcagatcg gacgagatca ccagcagcgc
     6121 gatgccttcg gcggcgaggc cgtcgatgat ccggtagatc tcggccttcg cgccgacgtc
     6181 gaccccgcgc gtcggctcgt cgaggatcag cagcttcggg cgccgcgcga gccaccgcgc
     6241 gagcacggtc ttctgctggt tgccgccgga gagcttgcgg acctcctgct ccatcgacgg
     6301 cgtccgcacc cgcagttcgc gcacgtactc ctcgacgagt tcgcgttcct tggcccgccg
     6361 caccacccgg aaccggcgca gccggtccag tacggcgatg gagacgttgt cgcgcacgga
     6421 tcgctgcatc agcaacgcgt cggtcttgcg ttcctcgggc gcgaacccga tccccgcctt
     6481 gaccgcgtcg ccgggagtac gggcacgtaa cggtttcccg tccagttcca cggttcccga
     6541 gcgcaccggc aggtcgccga cgatcgcgtg cgcgagttcc gaccgcccgg cgccgaccag
     6601 cccggcgaga cagacgacct cgcccgcgcg gacctccagg gagatgtccg cgacgtcgtc
     6661 ggtggtgacc tggtcgagtc gcagcacgac ccggccggtc tcctgcgtga cccggcgctc
     6721 caaagtggac agatcgcggc cgatcatcat gcgcaccagc cggttctcgt cggtggaggc
     6781 ggcgtcctcg accccgatca gcctgccgtc gcgcagcacc gccacgcgat cggcgagctg
     6841 gaagatctcc ttcatccggt gcgagacgta gacgaccgcc accccgctgt cccgtagccg
     6901 ccggatcagc gcgaacaacg cgtcgacctc gtgttcggac agcgacgacg tcggctcgtc
     6961 gaacgcgatc accttcgccg tcgtcgtcgc ggtgagcacc cgcaggatct cgaccagctg
     7021 ccgttgcgcg gcggacagcc tgctcccgag cgtctccggt cgcagcacgc cctcgaaccc
     7081 gtactcccgc aacgcttcct gcgtcatccg gtgcagggtc cgccggttga ccagccgtcc
     7141 ccgcgtcggc agttcgccga cgaagacgtt ctccgccacc gagacatgcg ggatgatctc
     7201 cggttcctgg tagatcaccc ggatcccggc ggccatcgcg gcgcgcgggc tgtcgaacgt
     7261 catgggaccg ccgtcgagca gcagccgccc gtcgtcggga ccgtggtcgc ccgacagcac
     7321 ccgcagcagg gtggacttcc cggcgccgtt ctcgcccatc agcgcgagca cctcgccggg
     7381 ccggaagtcc agggtgacgc cgtcgagcgc cgtcaccccg gagaaccgtt tgctgatccc
     7441 ttcggcggtc agcgccgccg cgggttcgga tgtggccatg gaaacgcctc cacgcgggat
     7501 cagatgcagt tgacgccggc ctgcttgtag ttgtccttgg tgacgatctg ggtcttcgcg
     7561 atcgtctccg ggggcagttc cttggagttc ttcaccttgt ccaccagcag tccgatcgcg
     7621 gtgcggccga cctcggcgcc ggagatgaac aacgccgact tgttgccggt gtccttgccc
     7681 gcggcccagt ccttgcaggt caggtacgcg ccgaggccga cgccgatgat gtcggcggcg
     7741 gggacgcccg agttcgccag cgcggtcacc gcgccggtct cgttctcgtc gttgcagccc
     7801 cagaccaccc agtgcttgac gccggggttc gagccgatca ccgcgccggt gcggttctgc
     7861 gcgtccaccg gggtgttgtc ggtgccgacc tcgatcaccg ggacctgggc accgctcttt
     7921 tgatcagaca gagtcttgtc gaaagcggcc ttcgccgccg agacgcggtc cgagcacacg
     7981 gtcaggtcct gcttgtaggc gctgatgatc ttggtgtcgg ccgcggtcca gcccgccgcc
     8041 ttgaacagct tcgcggcttc cttgccgacc gaatcgccca tctgcgagcc gttgaagccc
     8101 acgaacggcg acttcgtgcc gccgccgtcc ttgatcacgt cgtcggaggc gatgatcggg
     8161 atgcccgcgc tcttggcctt gtcgagcacc tgcgggccga tggcctggtc cgggacgacg
     8221 atcgcgatgc cgttggcgcc ctgggcgagc gcggcgtcga gttcggtgat cgccttgttg
     8281 gcgtcctgcc cgaggttgac gaccttgagt tcgacgccca gctccttcgc cttctcctgc
     8341 gcgccctgcg cctgctcgac gaagtactgc tgatcgccct gtttctgcag gtagaacagc
     8401 gtgaccttgc cgctcgcggg agcctgctgc tgcggtgtgg cggtctcctt cccggaagag
     8461 cagccggtca ccacgagacc agcaatcaaa caagaaccaa caatgcgcca aggcagggac
     8521 ctgtgcgaag ctgtggacat cgattgctcc caggatgaag cggaagagtg tgactcgtat
     8581 tactaatcac tcttccaggt gacgtcaagg cgcgatctgg tcacgaggaa cggctgtggt
     8641 cgtattaatc gccggtcagc agccgggttc ggcggcgagt ggtcctgtgg aacttgtccg
     8701 aagtttgtcc gatcggtgtt gttgactttg gttgagtgtc gcgcgcgatt cccgtaaggc
     8761 aggatgaaca agacaagtca cccgatcgag ggaaccgatg ttcagctccc gcgcccgtca
     8821 aggcaccgcc ctcctcgcca ccgccctgct gctggccgcg tgcagtacca cctccgagga
     8881 accgaagccg cccgccgcgt ccgaggcgcc aacgcaggcg agccaggctc cggacgggtc
     8941 gttcaccgtg gtcgcgaccg gtgacgtgct gatccacccc gcgctgaccg accaggccaa
     9001 ggaggacggc aagggtgaga tcgactaccg gccgctgctg gccgggatca agccgctgat
     9061 ctccggcgcc gacctcggca tctgccatct cgagacgccg ctcgcgccga agggcgggcc
     9121 gtacagcggc tacccgtcgt tcagcgcgcc gcccgagatc gtcgacgcgc tcaaggacac
     9181 cggctacgac aactgctcga cggcgtccaa ccacacgatc gaccagggcg cggacggcgc
     9241 gacgcggacg ctcgacaaac tcgacgaggc ggggatcaag cacaccgggt cggcacgttc
     9301 ggccgaagag gcgaagaagc cgctgatcgt cgacgtcaag ggcgttaagg tcgcccagat
     9361 ctccttcgcc tacgggttca acgggatcaa ggttcccgcg gggaaaccct ggctggtcaa
     9421 ccagatcgac gccgaagacg tgatcgccca ggccaaggct gcccggaagg cgggcgccca
     9481 ggtcgtcgtc gcgagcctgc actggggcac cgagtatcag cacgaagcga ccgccgaaca
     9541 gcgctcactg gcgaagaaac tcctcggtga cgactcgatc gacctgatca tcggccacca
     9601 cgcccacgtc gtgcagccct tcgagcagat caacggcaag tgggtcgcct acggcctcgg
     9661 caacagtgtc gcccggcatt cggaaccgaa gggctcgacc gaacagggcg cggccgcgcg
     9721 gttccggttc gtgcgggacg gcgaacgctg gaaggtcgac aaagccgagt acgtcccgac
     9781 cctggtccag ctcggcccgc cgatccggtt gctcgacctg accgccgggc aggccgggaa
     9841 cgccggcgcg gaagcgctca aggccaccga cgaggtcgtc ctcagccggg gagccggtga
     9901 gcgggggctg acccgcctcg gacgctgaaa ccttccgctc tgacagcgag tgggccgggc
     9961 cgcttcgacc ggcccacccg ctgcttttcc gcgcccgtct tcaataccgt cgccgcacca
    10021 ccagtttcgc gagggccgcg agctcggcgc ctgggcgggg caccgggttc gagacggcga
    10081 ggtggtgcag cgcgccggtc aggagcgcgt cggcctgctc ctggctccag gaccggccgc
    10141 ccgcccgttc caccagttcc gccgcgtggg gcaactccgc ggcttcgagg ttttccttgc
    10201 ggtacaaggc atccagttct cgcccggctt cggtcccgga gtggagcgcg gccaccaccg
    10261 gcagggactt cttccggttg gaaagatccg aatggaccgg tttcccggtc accgccggat
    10321 cgccccagat cccgaggaga tcgtcgatgt gctggaacgc cagcccgagt gccctcccgt
    10381 actcggtcag ccggtcgacc tgatcctgcc tcccttcccc ggcgatcgcg ccgagcgtgc
    10441 aggacgcccc gagcaacgcg ccggtcttcc cctcggccat gcgtacgcat tcggcggtgt
    10501 cgacgtcacc gcgttcctcg aacttcagat ccgcgctctg gccctccagt agttcgatca
    10561 cggccgtgct cagcacccgc agcgcggtct gcccgaacgg ggccagcatc tcgaaggccc
    10621 ggcacagcaa ggcgtccccg gcgaggatcg cggcgcccgt gccgaagatc gtccacgccg
    10681 tcgggcggtg ccgccgggtg gtgtcacggt ccatcacgtc gtcgtgcagc aacgagaagt
    10741 tgtgcaccat ctccaccgcg acccccaccg ggacggcgac ttcggcgtcg ccgccgaccg
    10801 cctgcgccga cagcagggcg agcgcgggac gcaacgcctt cccgccgtcc gaagtggatg
    10861 gacggccgtg ctcgtcccac cagccgaagt gataaccggc gatgagccgc atcgattccg
    10921 gcagcccgtc gacggcttcg cgcaacgccg gatcgagcag gttccggctc cacgccagta
    10981 cttcgttcgc gggccgggag ccgatgcggg tgtcgatcgt cgtcaacgga ttccccttca
    11041 gacttcgtga actgctgtta gcacaattcg cggatgccca attcgagcgg gcggacgcaa
    11101 cgtcaacata gcaagcggta atgctcggac aaacagctcg atcgggtctc gggagaggtt
    11161 cacctgtttg ccggattggc ccggacgcgg caaccgatga cggccgttcg ggctacgaaa
    11221 ctgctcgaaa tgtcggtatc cgacccggtg atgacgtcac gtggtggatc ctcactcggt
    11281 cgtgaaggcg ggctcgccga ccggtgacgc gccttttcgg tgcgtgtcgg aattcgtttc
    11341 gcgatatgag aagttgggcc gagccggtga tgatccactt tcacttatcc gccgcaggta
    11401 tgaattgatt caaccggtct tttcgcttgt cgaagcgtga actaggttca gcagtcatcg
    11461 cagggaagga gtcgaatggg tatttacctg accggcatcg cctgggtggt cggcgcggcg
    11521 gccttcgccg gattcgtcgg ctacctcgtc cgcaagttcg gctgggacga ggggcggccg
    11581 gacaacaacg acgccgcggg ccaggtgttc accatcgtcg gcgggttgca cgccgtcctg
    11641 gtcgcgttca tcctgatctc cctcttcgac tccgcgagcg cggcgcggga cggctcgtac
    11701 cacgaggcgg acagcctggt cgccgcggtc tgggccgcgg attccctggg tgacgaggtc
    11761 aaggtcgagg tccggaagct gagcgcggag tacatctcca cggtcgagaa gaaggagtgg
    11821 ccgcagatgg cgggcggcga ggagaccgtc tccggcgccg gctggacgca gctcgaccag
    11881 ctgcggaagg cggtcgacaa ggccccttcg gacgacgact ggttccgtga gcggaagacc
    11941 gaggcgtcca cccagctctg gcaggtctac gaggcgaggc aggcccggct caacgccgtc
    12001 gagggcggca aggtcggtgg tgtcgtctgg ttcgcgctca ttctcggcag cctcatctcg
    12061 gtgctgctgc ccaacctgtt cggtggcacc cggctggccg cgcatctggt gatcgtgtcc
    12121 acccttgccg gtacggtcac cctgctgttg ttcgcgatct accagctgca gaacccgttc
    12181 ggcggcgggg tacggatccc acccgacgcg ttcaccgccg cgctggcaag gctcacctga
    12241 accggtgagc actgtggacg gggtgacacg ggcggcggcg acggcggccg tcgccggact
    12301 ggtcggcgcg tcggcgctgc tggccccgat gacggcgcgt gccgccgagt cttgcctggt
    12361 ggtgcaggcg gagaccggct cgtacgggac gtcgaagctg cggtggctcg atgtcggctc
    12421 gggaaccact tcgcgggtga ccgaaccggg ctaccggctc aacgcgctcg gttactccgc
    12481 gacacgggat ctggtcttcg gtgtcgccga agggctcagc cgcggcgcgc acgcggtgtc
    12541 gatcgaccgt gacgggcgga ccgaggacct cggcccgatc acccgcgccg ggaaccggct
    12601 gccgctgtgg agtcccgtcg ccggggtgac cgccggcgcg atcggcggga actcctggta
    12661 cctgctgagg aacggcacac tgtacacagt ggacttgacg ccgggggagc ggtacctgcg
    12721 ggtgatcagg acggtgttcc tgcggccgat cacgctcgcc cacgacgtca acgatttcgc
    12781 gtaccacaac ggacttctct acggcgtctc caccacttgg cgcggaagag gcgcggtgat
    12841 cacgatcgac ccggcgtccg gcaaggtccg tgaagtcgaa gacgcccggt tcccgcctgc
    12901 cgacatctac ggttccgtcg tgctcgcccg cgacggtgcc ctgtacgcca cggcgaaccg
    12961 gatcggcggg cgcagcgtgc tgtaccgcct ggaccgcggc gggcaggtga ccgaggtgct
    13021 ttcgggtccg ccgctggcgg gttcggacgc ggcgggctgc ctcaccgcgc ccgagccgcc
    13081 ggaaccggag ccgcccaagc cgacacccac tcctactccg tccccgacgc ccacacctac
    13141 cccgtcaccc actccgactc cgagtccgtc acccagtccg acgccttcgc cgaacccgag
    13201 tcctagcccg agcccgacac cgagcccgag cccgacaccg agcccgagcc cggcaccgag
    13261 tcccacgccg acgtcctcac cgaggccgtc accaacgccg tcaccaacgc cgacttcgat
    13321 ggccaaagtg attccgccgc ccgctcccgt gccgaagccg tcccgtgcgg ccgcgcccaa
    13381 gcaggagaaa gcggcggcga aggccgatcc gcacgcgcgc acgaaggaga agcggcgatg
    13441 ggggctgacc gcgctggtcc tgatcctcgg cgggggagcg gcggccggtg ccgtccggcg
    13501 ggcccggtga gtcagtactt gaactggtcc acgttctcgc gggtgatcag cagcgggtca
    13561 ccgagcagca cggtcttccg gtctgcctcg tacttgatcg ccgggagttc gaggttgacc
    13621 ttgttcgacg ggccgagcgg tttgccctcg gcgatctgct tgcctgccca agcggtgagg
    13681 tagccgagtg actcgacgtt ccacagcacc gaaagcgacg cggaaccgtc cagaaggtac
    13741 ggcttgatcg ccgtcggcgt cccgacgccg acggtgaaga cgcggccgat cttctgctgc
    13801 gagcggaccg cctcggcgac ccctggcgcg gacgtcgtgc actcgccgac caggccggtg
    13861 agatccgggt acttgcgcat caggtccttg gccagcgcgg tggcgtactc cttgtcttca
    13921 ccggcgtaga ccgtctcgac gagctgcgca tggggatact ccgtagcggt atacgcacgc
    13981 tgaacggcga tccacgcgtt gaggttctct gccgtctcgc cgcaggagac gatcgcgtac
    14041 ttgcccgcgc cgcccatctt cttcatcagg gcgtcggtga gcgccttgcc gatgccctcc
    14101 ggggtcgcct ggttgacgaa gagttcgcga tcggtgccgg gcgcgtcggt gtccgaagtg
    14161 atcacatgga cgcccttggc ccgcgcgtcg gtgatcgccg gtgcgatcgc cctcgggtcg
    14221 ttcggggcga tcgcgatgac gtccacccgc tggtcgacga ggccccgcat gatcgagacc
    14281 tgcgccgcgg ggtccaccgt ggccggtccg gtcgaggtcc attcgacacc gagctgcttg
    14341 gcagcgtcgt gcccgccggt gttcatcgcc tcgaagtacg ggatgcccgc gaccttcggc
    14401 acgaacgcga tccggatcgg cttggccgtc acctcggcag gcgcgtcacc gccgcaaccg
    14461 gtcagcccga acaccatgcc ccaagcgagc acggcggcga cgacgagcgt cttggtcggc
    14521 cctcgcatct ccaccccata gtcacggaac cacttgaatc agccgatcgg tctgcgcgcg
    14581 gtggagacct ccgggcgaaa ctaaggtctt cggttacgcc ggtcaaccgg atgagcgcaa
    14641 agggttacgg aagtgagttc atcgacctgg gccgattacc gggtcggcct acgcaggtga
    14701 cggtgagcga ccgggagacg gggatcaccg cgccgcatat acgggtgggg ggtatatttc
    14761 cccgcatgaa cgagacacgg catggagcaa gctggtcgat ggccgcgtcg gcgaccctgc
    14821 actgcctcac cggctgtgcg atcggtgagg tcctcggcat ggtgatcggc acggcgctcg
    14881 gcctgcacaa cgcggggacg atcgtgctct cgatcgcgct cgccttcgtc ttcggttacg
    14941 cgctgaccat gcgcggcgtg ctgaagtcgg gcctcgcgtt cggcgccgcg ctcaaggtgg
    15001 cgctggccgc cgacacggtg tcgatcgcgg tgatggagat cgtcgacaac ggggtcatgg
    15061 tggtggtgcc gggcgccatg gacgccgggc tcgggagctt gctgttctgg ggcgcgctgg
    15121 cgttctcgct ggccgtcgcg tttgtgctga ctgtgccggt gaacaaatgg atgatcggac
    15181 gcggactggg ccacgcgaaa gtccacgcgc accacgctca ctaaacgcca gtccttcacg
    15241 gacttgggct ggagctaaac agccgagagg ccgatcgcct tgtcgatctc cttcggcatc
    15301 agcacccgca ggatgccttc gagcaggtag tagtcgccgt agggcaacga aacctcgaca
    15361 ccgtcctcgg cgggacggtt tcgcgtgccc cgcgccacga tcgcctcggc acgggcggac
    15421 ttcgtggtca ggcaggtgtc gcacaacgcg gtgaggatcc ggatcgccgc ctcgcggtac
    15481 tgcggccggt tcgcggcctt cgcgaggtcg agcaggccgc acgccatcac ggcgccggcg
    15541 gaggagtcct tgatgtcgtg cggcgcttgc ggcgctagct agtcccacac cgggacgttg
    15601 tccggggtca gggcgcggag cgcgaagtcc gccaggcgct gcgcggtccg caggaacagc
    15661 gggtcgccgg agcgccggta catcgtggtg aaaccgtaga tcgcccaggc ctgaccgcgt
    15721 gaccagcagg acgccggacc gtagccctgc acggagttcg ggccgatctc ggcgccggtg
    15781 tccgggtcga agtcgaacac gtgcggggtc gaaccgtccg ggcgcacgaa gacccgttcc
    15841 gtggtcttcg cgtgcgagac ggcgatgtcg aggtacttcc ggtcgccggt ctgttcgctc
    15901 gcgaaggtca gcaggtccag gttcatcatc gtgtcgacga tgacccggcc ggcgttgccg
    15961 ggggtgccga gcgcgcccca ggcccggatg aacttccctt tttcgttgta gcgctggatg
    16021 agtgacgcgg cggcgttgag cgcgccggtg cgccatttcc cgtcgccggt gagccgccag
    16081 ccggtcaccc aggacgggta gaacaggaat ccgaggtcgt gatcgctcgt ctcgtactgg
    16141 cgcggggcga gcttttccgc ggacgccgcg gcgagggccc ggaattgcgg atcgccgctg
    16201 tagatcgacg cgagccacaa agtgccgggc cagaaaccgc cgatccagcc gcccttcgcg
    16261 gaataggtcc atttctcgaa ccgggtgatc tccggaaagg tcgtcacgcc cggcgcgacg
    16321 gctcgcagct tggccaccgc gtaatcggcc gtccggcgga aagtccttag cccgtcggct
    16381 tcttctgtcg ccgcggtggc ggccggggtg atcgccgtcg ccgcgacggc ggcaccggca
    16441 gcggtggtca acagggttcg ccgggaaacg ctcacaacgc ccgccattcg tcagtgggaa
    16501 acgcgtgacg ggagtttcgc acgacgattc caggcttgtg aagaccattc atggttgtga
    16561 atagaagggc tcactcagcg ggacggatat tcgcgttgtg ccggaacacg ttgtccgggt
    16621 ctgcaccgcc cggcgcaagg ttttcccatg ccgtgaaaag ggcgaaggcc cggcggtatg
    16681 gggtccgccg ggccttcgcg ttcagggggt gactagcact tgggcgccac cggcagatcc
    16741 gaaccggtct gcaggtaggt gtcggaaatg tagtgtccgg ggccgatccg gtcccagatg
    16801 ttgctggtgc cgaatttgcc ggtgacggtg tcaccctcga cgtagcattc gatgttgacc
    16861 ttggcgtagt tcgctgcgag gcccttgatc gccgcgctcg tgctcgccga cgcccggacg
    16921 ttcatcgggt cgcccgccgt gctgacgacg ccggtcgggc cggagccgat ccacaggtag
    16981 gagacgttga cccagccgtt gtcggtcatc ttcaggccgt cccagaaggt gccgtccgcg
    17041 aggtcgatac ccgccgggtt cgcgggcttg cggccgaact cgtccttgcc gccgttgtag
    17101 ccgtcctggt acgcggcctg cgcctcgggc ttgccctgcg gcaggttctt ccacatctgg
    17161 cgggtggccg acgggttcca gtagtcgtcc ttggtgttcc acgggccgac gtcccacacc
    17221 ggcgcgtact cgcagcggct gttgtcggtg cggcagatcc gcacggtgta gttgccggtg
    17281 ttcttcggcg cgaggccgcg gcccgatggc agggcgacga agtggtcgcg ggacttgatc
    17341 acgtgcccgt tggcggtggt gccgccgacg agaccttcgc gggtgccgaa gaccttgtac
    17401 gtcagcgggg cggcggccgc gccgatcgcg ttgacctgcg ggccgagttc accctggagg
    17461 gtgacgtcgc tgaccttcgc ggtcacgccg tcggtcaggg tgcgcagtcc gatgcggacc
    17521 tggaccgtgg agaccgaagt ggacagctgg gcggcgccgc cttcggtggg cgtccactcc
    17581 gtccagtcgt tggagttcag cttgccccgg acgtcgacct cgacctcggt gcccttcggc
    17641 gcgtcggcgg tcacctgggc ggtgacgcgg ttgaccggct ttccgagctg ctgctcggcc
    17701 agcagcaggt aaccctggct gccgatggag tcgggttttc tgtgccaggc ggcgttttcc
    17761 aggctgagca cgccgccgtc gctgcggacg ttgacgtcgt cgccatccac agtggacagg
    17821 tcggcgcgcc agcttccttc gggcgccgcg ttcgcggggc tgggggccag tgcggtgacc
    17881 gcccccgagg ccagcacggc cagcacggcc gccatcacac ggcgggcctt cacggtccgg
    17941 accattccgg tctcccttcg agcactctcg gttgctacga atggagcttc gccgggacct
    18001 gtacacgatc gatacaaagc aagtcggcac ccggtcgcgt cacgtacacg cgatcaggtg
    18061 ccgacttggc gaagggtcag gcgctggcgg agtcgccgta agaggcttcg gcggactcct
    18121 gcagccgtga ggcgagcgcg gattcctgtg gccgcgcgga aagttcccgc cacaacgcca
    18181 gcgcgcgttc cgaatacgtc cgtgatcgtt cgggctggct cagtgcctcg tgcagttccc
    18241 cgagcaactg cgacacctcc gcctcggacc ggcggtcccc gttgcgccgg tgcacgctca
    18301 gcgaattgac cagcagcagc tgcgcgtggg ccagatcgcc gctgtgcaga tacagctcgc
    18361 cgaggttctg gttcgcgtag ccgacgcaat ggtcgtcgcc gagctcgttg aagatcgcga
    18421 tcgcgcggtc gacccgttcc cgcgcgcccg cgaggttgcc ctgatgctgc cgcagcatcg
    18481 cgagccgctt caacgcgtgc gcctcccgat gccggtcccc gatgtccgcc gcctgttcga
    18541 gcgcttcggt gaaccagtgt tccgcgtcgg cgaaccggcg ccgcgccagc cagaccgcgc
    18601 cgatcgcgat ccgcgcgacg gcctcgccgt gcggatcacc ggccgccgag aactggtcga
    18661 gcgcggcgtg acagtgctcc agcgcgacgg tgtcctcgcc cttgatccgc agcacggtgc
    18721 cgagcccggc cagcgcgatc gccgcgcccc gcgcgtcgcc gatcttgtcg aacagcagtt
    18781 gcgactgctc gaacgcgacc agggcctcgg cgtagctgtc ctggtacagc tggacctggc
    18841 cgaggttgcg ctggatgatc gcctccccgc ggatctctcc ggaccggcgg gcggcggcca
    18901 gcgcgacggc gtgcgtgtgc agccagtcgt cctgatgccc gcgctggtcg aagtacggcg
    18961 ccagcgcggc ggcgagccgc caggccagcc cgtcgaagcc gagttcggcg gccagcgaga
    19021 ccgcggcgac gcaggtgtgc cgctcgacgg cgaaccacgc ggccggatcc tcgaccagct
    19081 gcccggttcc gggcgggaga acgggctgga cggccgtgtc gtcccggtag agcccgaaga
    19141 agtggatcgg catccggtcc gccgcttcga gcgcgagcgc gagatatccc tcgagtaccc
    19201 gtttcgtggc gtcgtgcgcc ttcgccggga tgtcgtgcgc gcgcagttcg gcggcgtaac
    19261 accgcagcag gtcgtgcagc cggtagcggg gttcgccggt gccgtccgag ccgaggagat
    19321 cgaccaggtg ggcgtccacc agcacgtcga ggacgtcgtc cgcgtgcgcg cggccgagca
    19381 gggccgcgac cacccaggcg gggaactgga ccgaaccgag cccgccgaga ccgcggaacg
    19441 cgctcgccgc cgacatcggc aggaggtcgt agctgagcgt gacactggcc cggacggcca
    19501 gatcgccgac acggagttcg tcgagtcttc gtctctcgtc gcgcaatctg tccgccagta
    19561 cgcgcagcgt ccagcccggc cggtgggtca gcttcgctcc ggcgacccgg atcgccagcg
    19621 gaaggtagcc gcagtggcgc aggatcgccg tcgcggactc aggctccgca gtgaccctgt
    19681 cggcgccgac gatgccttcg agcagcttcg cggcttcggc ctcgggcagg aggtcgacgt
    19741 cgaccggggt ggccccggcc agatccggca tccgcacccg gctggtgatc agcaccgcgc
    19801 aggcgcccgc gccgggcagc agtggtcgga cctgcgccgc gctgccggcg tcgtcgagga
    19861 cgacgcacat ccgcagcgtc gccagccggg atcgcagcag cgccgcgcgt tcgggcagat
    19921 cacgcggcag ccccgcgtcg gggacgccca acgcgcggag caactcggcg agcacggtca
    19981 tcggcggccg gggcgaggac gacgtcccgg cgagatccac gtgcagctga ccgtccggga
    20041 aatcgtcccg gaccgcgtgc gccacccgga tcgcgaccga ggacttgccg atccccggcg
    20101 ctcccgaaag caccgcgatc gcgggcttcc cttgttcgcg acggtcgcgg aagaggccga
    20161 cgagttcgcc gaccacctcg tcgcggccgg tgaagtccgg caggtccagc ggcagctggc
    20221 agaccggtgc cgccggcctg gcgagggcga cggccacggc gtcctgcgcc ggggaaggcg
    20281 tcaagaccag cgaagcccgc agttcccgca gccgtggccc cggttcggtg ccgagttcct
    20341 cggccagtac cttttcggcc gtttcgtagg cttcgatcgc gtcggcggtg cggccgtcgg
    20401 cccgtaacgc gacgatcagc tgctgccaga gttcctcgcg caggggatgc tcggtgacca
    20461 ggccgcgcag ttccgcgacg gcctcggcgg tgcggccgag ttcgatcctc gcgcgcagcc
    20521 gttgttcctg gaccgcgagc cgcgattccg tcagccgggc cacggtcgcg ccccagccat
    20581 ggtcgtgggg gagcccttcg agtacctccc cgcgccacag cgcttcggcc tgatccagca
    20641 ggccgagggc ggattcggcg tccccgtggc cgagcgcgtc ctgtgcgcgg gcggccagct
    20701 cgccgaactt gatgtggtcg atctcccctg ggctggcttt gaggatgtat ccggatgccc
    20761 ggctgccgat gcgctccccg agtccggggt cgtggtcggc gagccgcttg cggagtgaat
    20821 ggacgtaggt gcggatgttc gccgccgccg aacggggtgc cgacgagggc cacaggacct
    20881 cgatcagcag ttcggtggag acgacgacgt tgggctggag caggagagca gcgagcagca
    20941 gacgtggttt ggggccgccg agcggcacca cctgtccgtc caccgccact tcgagcgggc
    21001 cgagaacgcg aaatccgaga atagtc
//
