MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AAD21216.2 BacR BGC0000310.5 NRPS:Type I 44.0 98.7 197.0 2.53e-63
AEE65494.1 response_regulator BGC0000223.5 PKS:Type II 40.0 97.8 177.0 2.73e-55
ALJ99879.1 FlsR3 BGC0001904.2 PKS:Type II aromatic 38.0 97.4 168.0 7.97e-52
ABI75119.1 transcriptional_regulator_OmpR_family BGC0000188.5 other:other 42.0 100.0 168.0 1.93e-51
AAX57187.2 atypical_response_regulator BGC0000201.5 PKS+saccharide:hybrid/tailoring 41.0 95.7 162.0 3.11e-49
AAS79471.1 putative_two-component_system_response_regulator BGC0000035.5 PKS 43.0 99.1 160.0 1.12e-48
CAH60130.1 putative_two-component_response_regulator BGC0000700.5 saccharide 40.0 102.6 155.0 1.19e-46
AEG64695.1 response_regulator BGC0000379.5 NRPS:Type I 44.0 97.4 154.0 1.84e-46
ABO65653.1 Subtilin_biosynthesis_regulatory_protein_SpaR BGC0000515.4 ribosomal:RiPP:Lanthipeptide 35.0 96.6 154.0 3.17e-46
MUL41494.1 response_regulator_transcription_factor BGC0002045.3 PKS:Type II 42.0 97.0 152.0 1.16e-45
QCT05734.1 Tri1 BGC0001983.3 other:other 41.0 97.4 151.0 2.92e-45
CAJ34389.1 putative_response_regulator BGC0000445.5 NRPS:Type I 39.0 97.4 151.0 3.27e-45
EDY47143.1 two-component_system_response_regulator BGC0000845.5 other:non-nrp beta-lactam 41.0 95.7 151.0 1e-44
ADM69285.1 transcriptional_response_regulator BGC0001727.3 ribosomal:RiPP 36.0 98.3 150.0 1.22e-44
BAQ25486.1 two-component_system_response_regulator BGC0001288.5 PKS 41.0 97.4 150.0 1.32e-44
KON97034.1 DNA-binding_protein BGC0002122.2 NRPS:Type I 36.0 96.1 148.0 4.34e-44
CAB60254.1 MrsR2_protein BGC0000527.5 ribosomal:RiPP:Lanthipeptide 33.0 98.3 147.0 1.4e-43
KON97026.1 PhoP_family_transcriptional_regulator BGC0002122.2 NRPS:Type I 36.0 98.7 147.0 1.44e-43
ACN38369.1 putative_two-component_system_response_regulator BGC0000714.5 saccharide 41.0 97.8 147.0 1.54e-43
CAF31457.2 putative_two-component_system_response_regulator BGC0000696.5 saccharide 42.0 96.1 145.0 4.34e-43
ARV75734.1 putative_two-component_system_response_regulator BGC0001603.3 saccharide 42.0 96.1 145.0 4.34e-43
AEE65471.1 two_component_regulater BGC0000223.5 PKS:Type II 39.0 95.7 142.0 1.26e-41
BBA97247.1 putative_two-component_system_response_regulator BGC0002383.3 PKS 38.0 96.1 141.0 1.35e-41
CAK15802.1 putative_DNA-binding_response_regulator,_OmpR_family BGC0000344.5 NRPS:Type I 41.0 91.8 141.0 1.38e-41
AGU42430.1 Cmm22 BGC0000842.5 other:non-nrp beta-lactam 37.0 97.8 139.0 1.36e-40
BAJ07866.1 putative_repressor-response_regulator BGC0000232.5 PKS 38.0 95.3 139.0 1.93e-40
WP_002554192.1 heavy_metal_response_regulator_transcription_factor BGC0002571.2 NRPS:Type I 38.0 94.8 137.0 8.04e-40
ASY03210.1 NsoR1 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 34.0 98.7 137.0 8.89e-40
OKI59850.1 transcriptional_regulator BGC0002477.3 PKS 38.0 95.7 137.0 9.91e-40
AVO00817.1 May18 BGC0001661.5 PKS 37.0 97.8 136.0 1.4e-39
AHW57766.1 PgaR1 BGC0000262.5 PKS:Type II+saccharide:hybrid/tailoring 39.0 95.7 137.0 1.95e-39
QKW60381.1 response_regulator_transcription_factor BGC0002288.2 NRPS:Type I 37.0 99.1 136.0 2.65e-39
AAB91594.1 SpaR BGC0000559.4 ribosomal:RiPP:Lanthipeptide 35.0 97.0 135.0 3.52e-39
AEK64499.1 EtnR BGC0000506.4 ribosomal:RiPP:Lanthipeptide 35.0 97.0 134.0 7.01e-39
ABB69091.1 hypothetical_protein BGC0000260.3 PKS 35.0 98.7 134.0 2.29e-38
CCH32754.1 Transcriptional_regulator BGC0002070.3 PKS 38.0 94.8 134.0 2.5e-38
WP_237282926.1 response_regulator_transcription_factor BGC0001596.3 PKS:Type II aromatic 38.0 95.3 133.0 3.52e-38
BAC79018.1 repressor-response_regulator BGC0000245.5 PKS 37.0 100.0 132.0 6.48e-38
WP_078621122.1 response_regulator_transcription_factor BGC0002000.4 PKS 36.0 101.7 133.0 6.94e-38
AZF85922.1 DNA-binding_response_regulator BGC0001963.2 PKS:Type I 36.0 98.7 131.0 1.4e-37
OWA25481.1 DNA-binding_response_regulator BGC0001438.5 PKS+saccharide:hybrid/tailoring 34.0 100.0 129.0 1.2e-36
CAD91201.1 putative_response_regulator BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 40.0 96.6 127.0 3.15e-36
ALJ99857.1 FlsR1 BGC0001904.2 PKS:Type II aromatic 37.0 90.1 126.0 6.94e-36
QDG00829.1 two-component_system_response_regulator BGC0002028.4 PKS 35.0 96.1 128.0 8.07e-36
AFI57015.1 QmnRg3 BGC0000133.5 PKS 39.0 96.1 126.0 1.01e-35
AQZ69221.1 DNA-binding_response_regulator BGC0001635.4 NRPS:Type I+PKS 40.0 96.6 126.0 1.24e-35
AAL15573.1 putative_response_regulator BGC0000511.5 ribosomal:RiPP:Lanthipeptide 33.0 97.0 126.0 1.34e-35
QDG00834.1 two-component_system_response_regulator BGC0002028.4 PKS 35.0 97.4 127.0 4.24e-35
QYC40300.1 Response_regulator BGC0002344.2 NRPS:Type I 39.0 96.6 124.0 6.91e-35
ADI71440.1 putative_transcriptional_regulator BGC0000203.3 PKS 36.0 97.0 124.0 8.5e-35
BAG71485.1 response_regulator BGC0000536.3 ribosomal:RiPP:Lanthipeptide 29.0 98.7 124.0 1.29e-34
POM23776.1 Transcriptional_regulatory_protein_SrrA BGC0002369.2 PKS 34.0 95.3 124.0 1.39e-34
CAB93669.1 RumR_protein BGC0000545.5 ribosomal:RiPP:Lanthipeptide 34.0 96.1 124.0 1.47e-34
ARO44672.1 positive_regulation_regulator BGC0001769.5 PKS 34.0 96.1 124.0 1.75e-34
MBW8699708.1 Transcriptional_regulatory_protein_YycF BGC0002140.2 PKS 34.0 96.1 124.0 1.75e-34
AAK06808.1 putative_regulator_SimReg1 BGC0001072.5 PKS:Type I+saccharide+other:aminocoumarin 35.0 99.6 123.0 4.53e-34
QHZ32185.1 sensory_transduction_protein_regX3 BGC0002047.2 PKS 34.0 97.4 122.0 5.24e-34
AAL15604.1 Sim1 BGC0000270.5 PKS 35.0 98.7 120.0 3.5e-33
ASY03216.1 NsoR2 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 31.0 96.1 119.0 9.23e-33
BAV17023.1 putative_transcriptional_regulator BGC0001384.5 PKS 33.0 96.1 119.0 1.2e-32
ADB02841.1 AzicR3 BGC0000202.5 PKS 34.0 100.4 118.0 2.23e-32
TRO56970.1 response_regulator_transcription_factor BGC0002361.3 PKS+saccharide 35.0 97.0 118.0 6.96e-32
ALK27911.1 putative_two_component_transcription_regulator BGC0001233.5 NRPS:Type I 39.0 97.4 116.0 9.13e-32
ADJ56358.1 NisR BGC0000535.4 ribosomal:RiPP:Lanthipeptide 29.0 98.7 116.0 1.2e-31
AGS77305.1 Two_component_response_regulator BGC0001178.5 NRPS:Type I 35.0 96.6 116.0 1.26e-31
AGO50631.1 positive_regulation_regulator BGC0000229.5 PKS:Type II+saccharide:hybrid/tailoring 32.0 96.1 115.0 4.04e-31
CAH10125.1 putative_repressor-response_regulator BGC0000268.5 PKS 34.0 97.0 116.0 4.2e-31
CAE53348.1 response_regulator BGC0000440.5 NRPS:Type I 35.0 96.6 114.0 4.47e-31
CAG15007.1 two_component_response_regulator BGC0000441.4 NRPS:Type I 35.0 96.6 114.0 4.47e-31
OKI81334.1 transcriptional_regulator BGC0002478.3 PKS 32.0 98.7 114.0 8.18e-31
ABA00873.1 NsuR BGC0000537.3 ribosomal:RiPP:Lanthipeptide 27.0 97.4 114.0 1.02e-30
AZM50118.1 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 37.0 96.1 113.0 1.4e-30
AAM80541.1 VanRst BGC0000290.5 NRPS:Type I 36.0 96.6 113.0 1.4e-30
AOT85874.1 response_regulator BGC0001789.3 ribosomal:RiPP 29.0 98.7 113.0 1.43e-30
AEX55159.1 putative_response_regulator_SlvR BGC0000549.3 ribosomal:RiPP:Lanthipeptide 27.0 98.7 111.0 7.14e-30
CCC21118.1 two_component_transcriptional_regulator BGC0000171.5 PKS:Type I 37.0 97.4 111.0 1.16e-29
AWR88437.1 putative_response_regulator BGC0001522.5 PKS 35.0 98.3 108.0 1.17e-28
CAG25752.1 putative_two-component_system_response_regulator BGC0000311.6 saccharide+NRPS:Type I 34.0 97.4 106.0 5.5e-28
AKA59107.1 two-component_system_regulator BGC0001619.5 PKS 32.0 97.8 105.0 1.21e-27
QUS58949.1 response_regulator_transcription_factor BGC0002123.3 NRPS:Type I+PKS:Trans-AT type I 32.0 96.1 103.0 1.06e-26
CAD91233.1 hypothetical_protein BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 45.0 47.4 95.0 1.71e-24
CQR60474.1 Transcriptional_regulator,_atypical_response_regulator BGC0001287.5 PKS 33.0 92.7 97.0 2.83e-24
AGG35708.1 two-component_system_response_regulator BGC0000883.5 other:other 43.0 52.6 92.0 8.94e-23
QXJ26481.1 response_regulator BGC0002370.2 NRPS:Type I 44.0 46.6 89.0 2.39e-22
DMB38_33825 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 46.0 50.9 90.0 2.47e-22
CYV09491.1 NisR BGC0002575.2 ribosomal:RiPP 26.0 96.6 92.0 2.92e-22
AHI58828.1 WelR3 BGC0000668.5 terpene:Monoterpene+other:other 40.0 47.4 88.0 3.98e-20
ABK32284.1 Jer4 BGC0000080.5 PKS 35.0 69.8 81.0 1.83e-17
ABK32252.1 Amb4 BGC0000014.5 PKS 34.0 69.8 79.0 8.47e-17
AAZ23070.1 possible_response_regulator BGC0000291.5 NRPS:Type I 31.0 97.8 71.0 1.91e-14
AFL68048.1 response_regulator_with_CheY-like_receiver_domain_and_winged-helix_DNA-binding_domain BGC0001524.3 NRPS:Type I+PKS 38.0 45.3 68.0 2.25e-13
AKA59096.1 LuxR-family_response_regulator BGC0001619.5 PKS 31.0 90.1 67.0 3.36e-13
CAL80818.1 two-component_hybrid_sensor/regulator BGC0000997.4 NRPS:Type I+PKS 34.0 53.9 69.0 4.92e-13
ABB05090.1 LipReg1 BGC0001003.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 31.0 90.5 64.0 3.53e-12
QBK47604.1 CebA BGC0002316.2 ribosomal:RiPP 36.0 50.4 65.0 3.98e-12
AEG64693.1 two_component_system_response_regulator BGC0000379.5 NRPS:Type I 38.0 48.3 64.0 5.05e-12
AUA09456.1 Transcriptional_regulatory_protein_LiaR BGC0002291.3 PKS 28.0 90.1 62.0 2.15e-11
CAF05631.1 hypothetical_protein BGC0001053.5 NRPS:Type I+PKS 31.0 47.8 62.0 5.26e-11
QWT72285.1 response_regulator_transcription_factor BGC0002430.3 NRPS:Type I+saccharide 30.0 78.4 61.0 5.79e-11
BBD82049.1 LuxR_family_transcriptional_regulator BGC0001920.4 ribosomal:RiPP 35.0 50.0 61.0 6.15e-11
QUQ72331.1 response_regulator_transcription_factor BGC0002349.3 PKS:Type I 32.0 50.4 61.0 6.51e-11
QDF63356.1 KyaR BGC0002346.3 ribosomal:RiPP 32.0 86.6 60.0 1.05e-10
ctg1_orf18 BGC0000053.5 PKS 27.0 91.8 60.0 1.1e-10
WP_122215947.1 response_regulator_transcription_factor BGC0002015.4 ribosomal:RiPP 28.0 100.0 60.0 1.17e-10
SFF02396.1 two_component_transcriptional_regulator,_LuxR_family BGC0001674.5 ribosomal:RiPP 35.0 50.0 60.0 1.58e-10
AHX24716.1 LuxR_family_transcriptional_regulator BGC0000200.5 PKS:Type II+saccharide:hybrid/tailoring 30.0 72.4 60.0 1.64e-10
CAB38597.1 two_component_system_response_regulator BGC0000315.5 NRPS:Type I 32.0 65.1 59.0 2.12e-10
BCD33686.1 bacterial_regulatory_proteins,_luxR_family BGC0002448.2 NRPS:Type I 33.0 50.4 59.0 2.74e-10
ALV82366.1 regulator BGC0001370.4 NRPS:Type I 27.0 97.8 59.0 3.98e-10
AQP25576.1 LuxR_family_response_regulator BGC0001590.5 PKS:Type II aromatic 32.0 50.0 58.0 5.32e-10
AXO35193.1 DNA-binding_response_regulator_LuxR_family BGC0001848.4 other:other 33.0 51.7 58.0 5.32e-10
ACI88885.1 AlnR6_two_component_response_regulator BGC0000195.5 PKS:Type II 35.0 50.0 58.0 7.12e-10
QHZ32201.1 response_regulator_transcription_factor BGC0002307.3 ribosomal:RiPP 33.0 50.0 58.0 7.6e-10
ADC45530.1 two-component_system_response_regulator BGC0000093.5 PKS:Type I 37.0 48.3 58.0 8.09e-10
EWM63043.1 two-component_system_response_regulator BGC0000679.5 terpene 33.0 51.7 57.0 9.96e-10
ABL09961.1 regulator BGC0000197.5 PKS:Type II+saccharide:hybrid/tailoring 29.0 70.3 57.0 1.1e-09
ADB02831.1 AzicR2 BGC0000202.5 PKS 29.0 71.6 57.0 1.27e-09
QBC75031.1 DNA-binding_response_regulator BGC0001968.3 NRPS:Type I 29.0 73.3 56.0 4.36e-09
AAZ23059.1 probable_putative_response_regulator BGC0000291.5 NRPS:Type I 28.0 96.1 54.0 1.29e-08
BAW35603.1 putative_DNA-binding_response_regulator BGC0002357.3 PKS+other:other 32.0 47.0 53.0 3.77e-08
AAU34214.1 two_component_response_regulator_MppU BGC0000388.5 NRPS:Type I 30.0 51.7 53.0 4.23e-08
WP_030193597.1 response_regulator_transcription_factor BGC0002669.2 ribosomal:RiPP 31.0 65.1 52.0 5.29e-08
ATD51275.1 two-component_system_response_regulator BGC0001650.4 NRPS:Type I 28.0 90.9 52.0 5.4e-08
ARF06225.1 LuxR_family_transcriptional_regulator BGC0001593.5 NRPS:Type I 33.0 51.7 52.0 8.9e-08
CAN02021.1 putative_two-component_system,_response_regulator BGC0000528.5 ribosomal:RiPP:Lanthipeptide 32.0 50.9 52.0 1.08e-07
QDQ37907.1 two-component_system_response_regulator BGC0001979.4 PKS 27.0 93.5 51.0 1.21e-07
EHK80177.1 two-component_system_response_regulator BGC0001447.3 PKS 32.0 50.4 51.0 1.8e-07
ACX83628.1 putative_two-component_response_regulator BGC0000221.5 PKS 30.0 50.9 50.0 1.97e-07
ACI88882.1 AlnR5_two_component_response_regulator BGC0000195.5 PKS:Type II 28.0 70.3 50.0 3e-07
QWF78530.1 Transcriptional_regulatory_protein_LiaR BGC0002142.2 PKS 29.0 52.6 50.0 3.63e-07
AKT74265.1 TxnRg4 BGC0002141.3 PKS 25.0 94.0 49.0 7.7e-07
BAW27696.1 regulator BGC0001764.4 NRPS:Type I 33.0 47.4 49.0 8.86e-07
EAW09112.1 sensor_histidine_kinase/response_regulator,_putative BGC0000983.5 NRPS:Type I+PKS:Iterative type I 25.0 56.9 48.0 3.85e-06
MCG7203797.1 response_regulator_transcription_factor BGC0000248.5 PKS 26.0 70.7 46.0 6.49e-06
BBA21064.1 putative_two-component_response_regulator BGC0001740.5 NRPS:Type I+PKS 34.0 37.9 45.0 6.7e-06
AAP03103.1 putative_2-component_system_response_regulator BGC0000874.5 other:other 26.0 94.0 46.0 7.56e-06