LOCUS       NZ_KB907502            22898 bp    DNA     linear   CON 21-MAY-2024
DEFINITION  [Pseudomonas] hibiscicola ATCC 19867 G370DRAFT_scaffold00005.5,
            whole genome shotgun sequence.
ACCESSION   NZ_KB907502
VERSION     NZ_KB907502.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      [Pseudomonas] hibiscicola ATCC 19867
  ORGANISM  [Pseudomonas] hibiscicola ATCC 19867
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 401697)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name :: Stenotrophomonas maltophilia ATCC 19867
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: ATCC 19867
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. R37654
            finishing_strategy                :: Missing
            environment                       :: Host
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi15375
            Type Strain                       :: No
            Funding Program                   :: DOE-CSP 2012
            Isolation Site                    :: Plant
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. R37654
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000382065.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 01:07:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,084
            CDSs (total)                      :: 4,007
            Genes (coding)                    :: 3,964
            CDSs (with protein)               :: 3,964
            Genes (RNA)                       :: 77
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 15 of 43
            Pseudo Genes (incomplete)         :: 31 of 43
            Pseudo Genes (internal stop)      :: 7 of 43
            Pseudo Genes (multiple problems)  :: 7 of 43
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:56:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6665
            Orig. end                         :: 29563
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB907502.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 408460
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Nikos  Kyrpides (nckyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-PGF and JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22898
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22898
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22898
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12898](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    430..443
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.79"
                     /tool="antismash"
     gene            686..1201
                     /db_xref="GeneID:90526513"
                     /locus_tag="G370_RS0114120"
     CDS             686..1201
                     /codon_start=1
                     /db_xref="GeneID:90526513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646745.1"
                     /locus_tag="G370_RS0114120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_019661179.1"
                     /transl_table=11
                     /translation="MRQSVSTVRVLSYALLAVAVAAGTTGCFKRGVKGDYALAPEMRPL
                     EVPPDLNLPATTGDNKVPTLSSATKPAAPVAAAPAVGNTGFTIAGGKDEAFAKVGTALE
                     GVEGVTIASRAQLLGSYDVAYEGSNFLVRVVAVDAGAYISAVDPRGLPATAEAPVKLIA
                     ALKAKLAQ"
     gene            complement(1371..1694)
                     /db_xref="GeneID:90526514"
                     /gene="fdxA"
                     /locus_tag="G370_RS0114125"
     CDS             complement(1371..1694)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526514"
                     /function="Ferredoxin"
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005994928.1"
                     /locus_tag="G370_RS0114125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferredoxin FdxA"
                     /protein_id="WP_004153066.1"
                     /transl_table=11
                     /translation="MPFVVTENCIKCKHTDCVEVCPVDCFHEGPNFLVIDPDECIDCTL
                     CEPECPVNAIFPEDDVPAGQESFVALNAELAKEWPVLTVRKDPPADAGEWDGKPDKLKL
                     LER"
     gene            1888..3312
                     /db_xref="GeneID:90526515"
                     /locus_tag="G370_RS0114130"
     CDS             1888..3312
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526515"
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661180.1"
                     /locus_tag="G370_RS0114130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar porter family MFS transporter"
                     /protein_id="WP_019661180.1"
                     /transl_table=11
                     /translation="MSQRQPGIASHGGENTAFIVLISCVATLGGFLFGFDSGVINGTVD
                     GLRQAFNSSEAALGFEVASMLLGCAVGAFLAGWLGDRLGRRGVLIVSALMFLVSALGAG
                     AAHASWLFIAARVLGGFAVGAASVMSPAYIAEVASARYRGRLATVQQMAIICGLFAAFL
                     SNYLLARAAGASTEPLWLGHEAWRWMFWMQALPSGLFLLLLLVIPESPRFLVVKGRPEQ
                     ARAVLARLYGEAAATAKQAEIEASLAQDQHKPRFADLRDKVTGRLRPILWVGIGLAMFQ
                     QLVGINVVFYYGAVLWQAVGFSESDALLINVLSGALSIGACLLTVLLIDRIGRKPLLWI
                     GSVGMSVALVLMVVAFASGSLADGRLQLSDGMGRLALVAANVYVVFFNMSWGPVMWVML
                     GEMFPNQIRGPALAVAGAAQWTSNFAITVTFPMLLAGIGLAGAYGIYTVAAILSIFFVV
                     RYVRETKGKELEQMEG"
     tRNA            complement(3700..3774)
                     /anticodon=(pos:complement(10404..10406),aa:Glu,seq:ctc)
                     /db_xref="GeneID:90526516"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="G370_RS0114135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Glu"
     gene            complement(3700..3774)
                     /db_xref="GeneID:90526516"
                     /locus_tag="G370_RS0114135"
     misc_feature    3718..3733
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.79"
                     /tool="antismash"
     gene            3821..5206
                     /db_xref="GeneID:90526517"
                     /gene="pcnB"
                     /locus_tag="G370_RS0114140"
     CDS             3821..5206
                     /EC_number="2.7.7.19"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:1990817 - poly(A) RNA polymerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006378 - mRNA polyadenylation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526517"
                     /gene="pcnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005409056.1"
                     /locus_tag="G370_RS0114140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="WP_019661181.1"
                     /transl_table=11
                     /translation="MPLGNPETSTGSANIISPATSPFSLRVIPRDQHTISRKDISPNAL
                     RVLYRLRDAGFGAYLVGGAVRDLLVNGQPKDFDVATDATPEQVKQLFRNCRLIGRRFRL
                     AHVVFGREIIEVATFRANSDDGSGDREMENGMLVRDNVYGTIEDDAIRRDFTCNALYYA
                     IEDFSVRDYTGGFEDVQARLMKLIGDPVQRYQEDPVRMLRAVRLAAKLGFQIEEGTAAP
                     IPHLAGLLNEAAPARLFEEVLKLFLSGHGVASFEGLERYGLLDVLFPESAKALKANRTG
                     ALRRMLVEGLANTDARVANDEPVSPAFLFALLLWPGFCRAQATLLKQGVAPEEAQRRAA
                     DRVTVQQLSTIALPRRFSLPMQEIWLLQSRFSSRQRKRVFRTLTHPRFRAAFDFLSLRQ
                     VASSEHAADVEFWREAQAQSGRELESSLDAMHSEEGDDESGAPRKRRRRRRRPGAPAGA
                     AGE"
     gene            5210..5695
                     /db_xref="GeneID:90526518"
                     /gene="folK"
                     /locus_tag="G370_RS0114145"
     CDS             5210..5695
                     /EC_number="2.7.6.3"
                     /GO_function="GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526518"
                     /gene="folK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338321.1"
                     /locus_tag="G370_RS0114145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="WP_019661182.1"
                     /transl_table=11
                     /translation="MTPAWIGLGANLGDAAATVGAAIAALDGLPGTRLRQASRLYATPA
                     WGNEDQLPFVNAVASVETILPADELLQAMLALEQRFGRVRDPAVHWGPRALDLDLLLYG
                     VQELDQPGLKVPHPYMHERAFVLVPLAEIAPDLAIPGHGRVRDAVVRVDACGITPIG"
     gene            5730..6545
                     /db_xref="GeneID:90526519"
                     /gene="panB"
                     /locus_tag="G370_RS0114150"
     CDS             5730..6545
                     /EC_number="2.1.2.11"
                     /GO_function="GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526519"
                     /gene="panB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416119.1"
                     /locus_tag="G370_RS0114150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-methyl-2-oxobutanoate hydroxymethyltransferase"
                     /protein_id="WP_019661183.1"
                     /transl_table=11
                     /translation="MSTHADSKPWTVPALAEAKRNGQKLVMLTAYDSSFARTFDANGVD
                     LILIGDSLGMVVQGHDSTLPVTVADMVYHTRAVARVLQRALLVADLPFGADATPERALD
                     ASLQLLQAGAEMVKIEGAGFKVDIIRYLVEREIPVCAHLGLTPQSVLRLGGFKIQGRGD
                     AARQLVKDARAVAAAGASIMVLECVPTPVAAEVTAAVEVPTIGIGAGPHCDGQVLVLHD
                     FLGLDSGHRRPKFVKDFLAEGGSVAGATRAFADAVRDGSFPDEQHAYAQ"
     gene            6542..7381
                     /db_xref="GeneID:90526520"
                     /gene="panC"
                     /locus_tag="G370_RS0114155"
     CDS             6542..7381
                     /EC_number="6.3.2.1"
                     /GO_function="GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526520"
                     /gene="panC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011259031.1"
                     /locus_tag="G370_RS0114155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="WP_019661184.1"
                     /transl_table=11
                     /translation="MIQTFNELGALREQIAHWKREGLRVALVPTMGNLHGGHHSLVTLA
                     RQYADKVVASIFVNPTQFGPDEDFSRYPRTPEADVAGLEQVGCDAVWLPSVEAMYPLGV
                     DKTTRMHAPGVSEVLEGTSRPGHFDGVCTVVARLFLQVQPDVAVFGRKDYQQLAVIRQM
                     VAELSFPIQIVGAEIVRDEDGLAKSSRNQYLSAEQRPVATAIHRTLLGMREGYVAGHPR
                     ERIEADATAALQAAGFQVDYAVLRTPELAEPTFDGGGRVALIAARLGTTRLIDNLEF"
     gene            7542..7922
                     /db_xref="GeneID:90526521"
                     /gene="panD"
                     /locus_tag="G370_RS0114160"
     CDS             7542..7922
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526521"
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011036943.1"
                     /locus_tag="G370_RS0114160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_019661185.1"
                     /transl_table=11
                     /translation="MHLSLLKTKIHRATVTHSELNYEGSIAIDDNLLDATGIREFEQVH
                     IWDVTNGARFSTYAIRAEAGSGVVSLNGGAARHVQVGDIIIIAAFASMTEQEADSFKPK
                     LVYVDGKNQITHTNDTIPTQAA"
     gene            7919..9433
                     /db_xref="GeneID:90526522"
                     /gene="pgi"
                     /locus_tag="G370_RS0114165"
     CDS             7919..9433
                     /EC_number="5.3.1.9"
                     /GO_function="GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526522"
                     /gene="pgi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661186.1"
                     /locus_tag="G370_RS0114165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="WP_019661186.1"
                     /transl_table=11
                     /translation="MTTNNGFDSLHSHAQRLKGASIPSLLAAEPGRVQDLALRVGPLYV
                     NFARQKYDAAALQALLALAAERDVGGAITRLFRGEQVNLTEGRAALHTALRGDVVDAPV
                     AAEAYATAREIRQRMGVLVRALEDSGVTDVVSVGIGGSDLGPRLVADALRPVSGARLRV
                     HFVSNVDGAAMQRTLATLDPAKTAGILISKTFGTQETLLNGQILHDWLGGSERLYAVSA
                     NPERAAKAFAIAADHVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLEGAAQMDAH
                     ALDAPLERNLPVLHGLTDIWNRNLLGHATHAVMTYDQRLALLPAYLQQLVMESLGKRVQ
                     RDGQPVTTDTVPVWWGGAGTDVQHSFFQALHQGTSIVPADFIGCVHSDDPYTINHQALL
                     ANLLAQTEALANGQSSDDPHRDYPGGRPSTLILLDALTPQALGALIAMYEHAVYVQSVI
                     WNINAFDQFGVELGKQLASGLLPALQGEDVAIADPMTREILAQLKR"
     CDS             9510..9623
                     /gene="allorf_016175_016288"
                     /locus_tag="allorf_016175_016288"
                     /protein_id="allorf_016175_016288"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPMQRIRVPAAAQLDYAWRANAVCMGGCTCHPVSLAA"
     CDS_motif       9510..9560
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPMQRIRVPAAAQLDYA"
                     /locus_tag="allorf_016175_016288_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9561..9623
                     /prepeptide="core"
                     /locus_tag="allorf_016175_016288_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="2011.4"
                     /monoisotopic_mass="2009.9"
                     /core_sequence="WRANAVCMGGCTCHPVSLAA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPMQRIRVPAAAQLDYA"
                     /leader_location="[9509:9560](+)"
     misc_feature    9707..9725
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 27.95"
                     /tool="antismash"
     gene            9714..9920
                     /db_xref="GeneID:90526523"
                     /locus_tag="G370_RS0114170"
     CDS             9714..9920
                     /codon_start=1
                     /db_xref="GeneID:90526523"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268305.1"
                     /locus_tag="G370_RS0114170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6229 family protein"
                     /protein_id="WP_010484314.1"
                     /transl_table=11
                     /translation="MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGAAATEAALTGASD
                     TMITGGTNECTTTVSVINHCLCC"
     CDS_motif       9714..9866
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGAAATEAALTGASDTMITGG"
                     /locus_tag="G370_RS0114170_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9867..9920
                     /prepeptide="core"
                     /locus_tag="G370_RS0114170_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.40"
                     /molecular_weight="1751.0"
                     /monoisotopic_mass="1749.8"
                     /core_sequence="TNECTTTVSVINHCLCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGAAATEAALT
                     GASDTMITGG"
                     /leader_location="[9713:9866](+)"
                     /alternative_weights="1769.0"
     gene            10001..12898
                     /db_xref="GeneID:90526524"
                     /locus_tag="G370_RS0114175"
     CDS             10001..12898
                     /codon_start=1
                     /db_xref="GeneID:90526524"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268048.1"
                     /locus_tag="G370_RS0114175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_019661187.1"
                     /sec_met_domain="DUF4135 (E-value: 3.8e-79, bitscore:
                     261.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5.5e-34, bitscore:
                     111.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASPAAAAFARITEHFLAQARAALAAGLHDPAIALQPGERALLH
                     SQGEAALREHAQLKLNRVLLLELHAAARSGDIGPLDSAGALDEFVALATSEGFRAHLQQ
                     RYPVLLPRLTRMLEGQCAAVVELAARIGSDRVALAELLGAPAGTLHAVALGRGDLHGGG
                     RTVARLQFEGGTVMYKPRSLRIDATLDGLLSAVFGDAPDRVRVPKVIDRGSHGWAAFAA
                     HRYCSGEAELRCYYRGLGHWLAILRLIGGTDIHLENLIAVGPVPVVVDAESVFCRVIEI
                     EPSGLGDAYDTAVKLMRNSVLRTGIVPFRTAGLGMEGVDLSAAGALPGEQPRVQVPVIV
                     DDGTEPARLGMVEAEVSIAQNHPSAQPDVSLYWDHISEGFIDASGRLRALDANGELMPL
                     LTAFEGCQVRDVRRPTMAYAELGRMLWHPASLHNEARAVERAIDLLVRNAAVSPAAPSD
                     LETVRGEVDDLRHGDIPIFASQLDAARIHSVVANWRAMRIDLEDVTIRSTLVATDLNQH
                     ALARAEARSGYSYAARHPRADDLDARRRTLATRAVESLLRLAVHGEDGSMTWITPEVTR
                     TGWTVQPVQPDLYFGLGGIAFALAAYRHEVEQGRADPVAGLDPAIEGALAVFQTLCERH
                     PAEIDGGFVGTGSQMWALLALHDLLQRPALLALAERCAEAAEHRGFQQAAKFELIDGVS
                     GMILPLLALAEATGNARWLELAAAAGRRMQDAAIVDADGARWPTPQFSEPIGGFGHGAM
                     GMGWALARLARSEAGSVPERAAWWRLAEGAFAFQAALFEPHTGHWRDIHLQDGQKNFPT
                     WCHGSVGIGLAAADLYARTGDAAQLRDMRRAVADARGKWGFSHTLCHGDVSTRELLVLA
                     AALDPAGCPYPQDEAAIEIISSIEEHQGMVGGLTRAAFTPGLMIGLAGSIYGFLRMHPA
                     CVLPSPLLQETMATRADACAVRSSAAQDRPALVEA"
     gene            complement(12920..13483)
                     /db_xref="GeneID:90526525"
                     /locus_tag="G370_RS0114180"
     CDS             complement(12920..13483)
                     /codon_start=1
                     /db_xref="GeneID:90526525"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005409063.1"
                     /locus_tag="G370_RS0114180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_005409063.1"
                     /transl_table=11
                     /translation="MSASTLGLLVDDDELYLRTLQRSLARKGLETQTAQDAASALALAR
                     QHPPAFALIDLKLGSDSGLALIQPLRALRADMRILLVTGYASIATAVEAIKLGADDYLP
                     KPATVPMILRALGEEDDGPADDGEMEVPDAMTPISRLQWEHIQQAMHETGGNVSAAARL
                     LGMHRRSLQRKLAKRPSPERDPSR"
     gene            complement(13480..14706)
                     /db_xref="GeneID:90526526"
                     /locus_tag="G370_RS0114185"
     CDS             complement(13480..14706)
                     /codon_start=1
                     /db_xref="GeneID:90526526"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661188.1"
                     /locus_tag="G370_RS0114185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_019661188.1"
                     /transl_table=11
                     /translation="MTGPDAPFLRTLCSLRWLAVGGQAATILVASWVLGLPLPQLPLWA
                     GVAVLTLFNIYTQLRPEAADTAPLTAFGHILVDVIILTWMVGWSGGMANPFSSLFLILI
                     ALAAFALPLRWALAVALACLLGYAASGIFGQPLPDGYFRAQDLNRWGVVANFLISAAVV
                     LTFSTRLALALRQRELELSALRERFARNEGIVALATHAASVAHELNTPLATMTLLADDV
                     AERSEEPEVREDMETLRELLVQCRERVLALAAPASADAPGRSHSSAQQVLEQWRLVRPT
                     IDLHRNDDAPLRLPLDPGVGHLLMVLLNNAADAGEQAGRPRVDLDLRIEGDDLIGEVRD
                     YGHGFDARAAVLPGKLFGSSKSEGMGVGLALSHATIERLDGEMWMRPAQGAGSRVGFRL
                     PLVPREETP"
     misc_feature    complement(13825..13827)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14821..16086
                     /db_xref="GeneID:90526527"
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="G370_RS0114190"
     CDS             14821..16086
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526527"
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300453.1"
                     /locus_tag="G370_RS0114190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_019661189.1"
                     /transl_table=11
                     /translation="MHDAVTRPTPPSDATSWPRRQTHAVQIGGVTVGGGKPVVVQSMTN
                     TDTSDVASSVKQVAELWRAGSEMVRLTVNTVEAAAAIPRIVDKLAMMGIDVPLIGDFHY
                     NGHQLLTAEPACAEALAKYRINPGNVGFGKKKDLQFAQLIEFAIRYNKPVRIGANWGSL
                     DQALAAKLMDENSLREQPWDAGRVLREALIRSALDSAEQAVELGLPRDRIVLSAKVSGV
                     QELIAVYRDLAQRSDFALHLGLTEAGIGSKGIVASAAALGVLLQEGIGDTIRISLTPEP
                     GQSRTQEVIVAQELLQTTGQRAFTPLVTACPGCGRTTSEFFQELAKVVQNHVREKMPLW
                     KIHHPGAENMTLAVMGCIVNGPGESRHANIGISLPGTGETPAAPVFVDGEKKVTLRGDN
                     IAQEFVALIDDYVEHTYVRSAG"
     gene            16067..16816
                     /db_xref="GeneID:90526528"
                     /locus_tag="G370_RS0114195"
     CDS             16067..16816
                     /codon_start=1
                     /db_xref="GeneID:90526528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646755.1"
                     /locus_tag="G370_RS0114195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_019661190.1"
                     /transl_table=11
                     /translation="MSEAPDKPAILAAPESASGFRHWMARNAWRLVLLFGGVLLPLAGF
                     VALADEVHEFESFHFDAPLLWQMHGLHSPLLDRFFVLISKLGYEWFLIPADVLIIGVLL
                     GYRRWREATFVAVSFVGSALLNMGSKHFFQRQRPSLWESIAPESTFSFPSGHAMGSMTL
                     AVTLVLLAWNTRWRWPVLLLAPAFSLLVSVSRVYLGVHYPSDILAGWCAALVWVVGCYL
                     VMFSHRHPWRHHGTRPAKASEASSQGD"
     gene            17017..17664
                     /db_xref="GeneID:90526529"
                     /locus_tag="G370_RS0114200"
     CDS             17017..17664
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526529"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011408972.1"
                     /locus_tag="G370_RS0114200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator"
                     /protein_id="WP_019661191.1"
                     /transl_table=11
                     /translation="MTIRVYLVDDHALVRTGMKMILSGETDIEVVGEAETGEDALREVR
                     QLLPDVVLCDLHLPGVSGMEVTERIVRSHRNTRVVIVSVLEDGPLPKRLLEAGAAGYIG
                     KGCDAQELLRAVRDVAGGRRYLGTSIAQNLALSTVEGNGSPFDSLSPRELEVALLLTQG
                     LRQEDIARWLSLSAKTVNTHKARLFEKMGIHDNIALARMASQYGLVDPARPL"
     gene            complement(17984..18643)
                     /db_xref="GeneID:90526530"
                     /gene="eda"
                     /locus_tag="G370_RS0114210"
     CDS             complement(17984..18643)
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /GO_function="GO:0008675 -
                     2-dehydro-3-deoxy-phosphogluconate aldolase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008700 - 4-hydroxy-2-oxoglutarate
                     aldolase activity [Evidence IEA]"
                     /GO_process="GO:0009084 - glutamine family amino acid
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526530"
                     /gene="eda"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265926.1"
                     /locus_tag="G370_RS0114210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="WP_019661193.1"
                     /transl_table=11
                     /translation="MGIEQHQVKAAELLHAAGILPVVTVHTLDQARAVSAALLDGGLPA
                     IELTLRTPVAMEALAMLKRELPDVVVGAGTVLTVEQMQQSIDAGADFLVTPGTPPALAD
                     ALAAAPLPVVPGAATPTELLSLYARGFRVCKLFPATAVGGLAMIKGLAGPVADLKLCPT
                     GGITENTAAEYLEQKNVVCIGGSWMVPGNWIANGEWDKVRASAADAAKIIKRVRDH"
     misc_feature    complement(18611..18620)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    complement(18841..18856)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.9"
                     /tool="antismash"
     gene            complement(18849..20765)
                     /db_xref="GeneID:90526531"
                     /gene="edd"
                     /locus_tag="G370_RS0114215"
     CDS             complement(18849..20765)
                     /EC_number="4.2.1.12"
                     /GO_function="GO:0004456 - phosphogluconate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526531"
                     /gene="edd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015472018.1"
                     /locus_tag="G370_RS0114215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphogluconate dehydratase"
                     /protein_id="WP_019661194.1"
                     /transl_table=11
                     /translation="MSLHPQLQAITERVIRRSAASRAAYLAAIDASLREGPFRSRLSCG
                     NLAHGFAACGGTDKSRLRGGVTPNLGIITAYNDMLSAHQPFETYPEQIRQIARELGATA
                     QVAGGVPAMCDGVTQGRGGMELSLFSRDVIAQATAIGLSHDMFDTTVYLGVCDKIVPGL
                     LIGALAFGHLPAVFVPAGPMTPGIPNKQKAEVRERYAAGEATREELLEAESASYHGAGT
                     CTFYGTANSNQVLLEAMGVQLPGASFVNPGTPLRDALTREATERALDITALGDDFRPLG
                     RIIDERAIINAVIALMATGGSTNHTIHWIAVARAAGIVLTWDDFDELSQLIPLLARVYP
                     NGEADVNRFAAAGGPAFVFGELIKAGLMHGDLVSVARGGMADYAREPQLRDGQLVYLPG
                     LERSADDEVVRGVDNPFEHQGGLRLLRGNLGKSLIKLSAVKPKYRTIEAPAVVVDAPQV
                     LNKLHAGGLLPEHFVAVVRYQGPRANGMPELHSLAPLLGLLQNQGRRVALVTDGRLSGA
                     SGKIPAAIHVTPEAARGGPLAKVREGDMIRLDGEAGTLEVLVDPAEWAARPLAPNTAPA
                     AHDLGRNLFAVNRRVVGPADQGAMSISCGPAAADGGPWEYDAEYELGHDAAAAAAPHEA
                     KDA"
     gene            complement(20824..21546)
                     /db_xref="GeneID:90526532"
                     /gene="pgl"
                     /locus_tag="G370_RS0114220"
     CDS             complement(20824..21546)
                     /EC_number="3.1.1.31"
                     /GO_function="GO:0017057 - 6-phosphogluconolactonase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526532"
                     /gene="pgl"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479767.1"
                     /locus_tag="G370_RS0114220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="6-phosphogluconolactonase"
                     /protein_id="WP_019661195.1"
                     /transl_table=11
                     /translation="MSPTLHDDRIEFIQHGDADGWIEAVAAEMAQTLNHDINEVGRARI
                     LLSGGTTPAPVYQALAELDVHWDRVEVSLADERWLSPQDRDSNAWLVREHLLKRAEGAH
                     FDPLVRIGKPLTECVYTANLQAQHSQPPSLVALGMGNDGHTASLFPGSKDLARALESTL
                     PYAALDATGCPGANQWPLRITLTPHGLRQCRQRLLLLRGKQKLQVLRQALDSNDPQQYP
                     ILNAINLEGARLRVHWAD"
     gene            complement(21543..22550)
                     /db_xref="GeneID:90526533"
                     /gene="glk"
                     /locus_tag="G370_RS0114225"
     CDS             complement(21543..22550)
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90526533"
                     /gene="glk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416128.1"
                     /locus_tag="G370_RS0114225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucokinase"
                     /protein_id="WP_019661196.1"
                     /transl_table=11
                     /translation="MSAISQPVLVADIGGTNARFALADTSQDAPLLKESIREYAVAEFP
                     SLGDAARHHLEQIGAAASRGVFAVAGRVDGDEARITNHPWVISRSRTAAMLGFDELHLI
                     NDFAAQAMAISLLQPEDVVQVGGAAWVPGKPGQPRNYAVIGPGTGLGVGGLIMRHGRCY
                     PLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRAVCEMAGIDPG
                     QLQPVDVTARALHGDPQAMRTVDVFCAVFGAIAGDLVLTQGAWDGVFLTGGLTPKMLDS
                     LQHSGFRQRFEHKGRFSSIMARVPSLAVMHPHAGLLGAAAYAADAERDAPGVAA"
     misc_feature    complement(22752..22767)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.18"
                     /tool="antismash"
     misc_feature    22753..22766
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.0"
                     /tool="antismash"
ORIGIN
        1 ccggtactgc caaaaccatc gaacagaccc gtcgtgcggc cgcgcttggc gccagccatg
       61 cactggtggt caccccgcct tacgtaaggc cgacccaggc cggcctgatt gcccattatc
      121 gtgcggtcgc cgaccagggc gggttgccgg tcgtgctgta caacgtgccc ggccgtaccg
      181 gttgcgacat gcagccggag accgtggccg aactggccag ccaccccaac atcgtcggca
      241 tcaaggaggc ggtgggcgac accggccggg tgcaggcgct gctggcgctg cgcagcccga
      301 agttcgcggt cctcagtggc gatgacggca ccgccgcgcg ctcgatccgg gccggcatcg
      361 atggcctgat ctccgtgggc tccaacgtgc ttccgggtgc ctaccgccgg atgtgcgaac
      421 tggccgccgc gcacgaccat gcagccaccg aatcctggga cgcgcgcctg cagccgttcc
      481 acgatttctg cggcgttgaa ccgaacccga ttccggtcaa ggcgctgctg cgccgcatcg
      541 gtgtcggcca tgacctgcgc ctgccgctgc tgccgctgtc ggcgccgcac catgcggccg
      601 ccgaccacct tgccggcgac atcgccgccc tcgaagccct ttccagccac tgaccttccg
      661 tcttggtctg acccaggaga ttcacatgcg tcaatccgtt tccaccgtcc gcgtgctgtc
      721 ctatgccctg cttgctgtgg cggtcgctgc cggcaccacc ggctgcttca agcgcggcgt
      781 caagggcgac tacgccctgg ccccggaaat gcgtccgctg gaagtgccgc cggacctgaa
      841 cctgccggcc accaccggcg acaacaaggt gccgaccctt tcctcggcga ccaagccggc
      901 ggccccggtg gctgcggccc cggccgtggg caacacgggt ttcaccatcg ccggtggcaa
      961 ggatgaggcc ttcgccaagg tcggcaccgc gctggaaggc gtggaaggcg tgaccatcgc
     1021 cagccgcgcg cagctgctgg gctcgtatga cgtggcctac gaaggcagca acttcctggt
     1081 ccgcgtggtg gccgtcgatg ccggcgccta catctccgcg gtggacccgc gcggcctgcc
     1141 ggccacggcc gaagcgccgg taaagctgat cgccgcgctc aaggcgaagc tggcgcagta
     1201 agggctggtc gggtggatgc gggccttggt ccgcacctgc cttgggtagc gccgggccat
     1261 gcccggcgag cttgaagcgc ggcccaggat ccgccgggca tggcccggcg ctaccggaaa
     1321 tggaaaaggg cgcccaaggc gccctttttc gttgtcgcag caggcgcttc tcagcgttcc
     1381 agcagcttca gcttgtccgg cttgccatcc cattcgccgg cgtcggcagg cgggtccttg
     1441 cgcacggtca gcaccggcca ctccttcgcc agctcggcgt tgagggcgac gaagctctcc
     1501 tggccggcag gaacatcgtc ctccgggaag atcgcgttga ccgggcattc cggttcgcac
     1561 agggtgcagt cgatgcactc atccggatcg atcaccagga agttcgggcc ttcgtggaag
     1621 caatccacgg ggcacacttc cacgcaatcg gtgtgtttgc acttgatgca gttttcggtg
     1681 acgacaaagg gcatgggctg ggggcggatc gattcctgaa cccgccaatt ctagaacagg
     1741 ttggccccca gtgtcggcgc ggggcggaaa tcgggcgcct ggcaggcgcg gccgtggcgg
     1801 acattggcgg cagggcaagg cctgtgcgac gctgcgggtc agccggctgc gtcggatggc
     1861 cggcctccct tcccaacagg ttcatccatg tcccagcgcc aacccggcat cgcctcccac
     1921 ggcggcgaaa acacggcatt catcgtcctc atcagctgcg tggccaccct cggtggattc
     1981 ctgttcggct tcgatagtgg tgtcatcaat ggcacggtcg acggccttcg ccaggccttc
     2041 aactccagcg aggcggcgct tggtttcgaa gtcgcttcga tgctgctggg gtgtgcggtc
     2101 ggtgccttcc tggcaggctg gctgggggat cgcctgggcc gccgaggcgt gctgatcgtg
     2161 tcggcgctga tgttcctggt ttcggcgctg ggcgccggtg ccgctcacgc ttcctggctg
     2221 ttcatcgccg cgcgcgtgct gggcggtttc gcggtgggcg cggccagcgt gatgtcgccg
     2281 gcctacatcg ccgaggtggc ctcggcgcgc tatcgcgggc gcttggccac ggtgcagcag
     2341 atggcgatca tctgcggcct gttcgccgcc ttcctcagca attacctgct ggcccgtgcc
     2401 gctggggcgt cgaccgagcc gctatggctg ggccatgagg cctggcgctg gatgttctgg
     2461 atgcaggcgc tgccatcggg gctgttcctg ctgctgttgc tggtgattcc cgaaagcccg
     2521 cgcttcctgg tcgtgaaggg gcgcccggag caggcgaggg cggtgttggc gcggctgtac
     2581 ggcgaggccg cagccacggc caagcaggcc gagatcgagg cgagcctggc ccaggaccag
     2641 cacaagccac gcttcgccga cctgcgcgac aaggtcaccg gcaggctgcg cccgatcctc
     2701 tgggtcggca tcggcctggc gatgttccag cagctggtcg gcatcaacgt ggtgttctac
     2761 tacggcgcgg tgctgtggca ggcggtgggg ttctcggaaa gcgacgcgct gctgatcaat
     2821 gtattgtccg gtgcgctgag catcggtgcc tgcctgctga cagtgctgct gatcgaccgc
     2881 atcggacgca agccgctgct gtggatcggc tcggtcggca tgtcggtagc gctggtactg
     2941 atggtggtcg cgttcgccag tggcagtctc gccgacggtc gcctgcaact gtccgacggc
     3001 atgggccggc tggcgctggt ggcggccaac gtctatgtgg tgttcttcaa catgtcctgg
     3061 ggcccggtga tgtgggtgat gctgggtgaa atgttcccca accagatccg cggcccggca
     3121 ttggccgtcg ccggtgcggc gcagtggacg tcgaatttcg cgatcaccgt gacgttcccg
     3181 atgctgctgg cgggcatcgg cctggccggg gcctacggga tctatacggt ggcggccatc
     3241 ctctcgatct tcttcgtggt ccgctacgtg cgcgagacca agggcaagga gctggagcag
     3301 atggaaggct gacgctgccc ggcttcggtt gcattccgtt ggcgcctcgg tgtcatcgag
     3361 ggcgaaggcg gggcagccca atccgggaca cgccgtgaac ccatccatgg gggctcgatg
     3421 gcgccatcca tggcgccaac ggtcccggct tgagctgccc cgccttcgcg tcaggcattg
     3481 cggttctggc ggacgcaggt ctgcgcgtcg ggattgaatt ggctgcggag gagcgaggct
     3541 gttcgtgccg ccgtcgcggg aaactgtcag ggtggcccac cccctcccac gcaggaacag
     3601 gaaggcgcta ctgcgaccag gccgaccgat gccgatgcaa accccggaaa acagaaaagc
     3661 ccgcacaagg cgggcttttt cggttcctgc tgcggcgact ggcgctccct aggggactcg
     3721 aacccctgtt ttagccttga gagggccacg tcctaaccac tagacgaagg gagcgtaact
     3781 gtgtcgctgc cgaggcagga gcgctagtat atgcacctcg atgccattgg gcaatcccga
     3841 aacttcaacc ggaagcgcca acatcatttc ccctgctaca tcaccgttca gcctgcgcgt
     3901 catcccgcgc gaccagcaca cgatctcccg caaggacatc agcccgaacg ccctgcgcgt
     3961 gctttatcgc ctgcgcgatg ccggcttcgg cgcctacctt gtcggcggcg cggtgcgcga
     4021 tctgctggtc aatggccaac ccaaggattt cgacgtggcc accgacgcca cgcccgaaca
     4081 ggtcaagcag ctgttccgca actgccgact gatcggccgc cggttccgcc tcgcccacgt
     4141 tgtgttcggc cgcgaaatca tcgaagtcgc caccttccgc gccaacagcg atgacggcag
     4201 cggcgaccgc gagatggaaa acggcatgct cgtgcgcgac aacgtgtacg ggaccatcga
     4261 agacgacgcc atccgccgcg acttcacctg caacgccctg tactacgcca tcgaggactt
     4321 ctcggtgcgc gactacaccg gtggcttcga ggacgtgcag gcgcgcctga tgaagctgat
     4381 cggcgacccg gtgcagcgct accaggaaga cccggtacgc atgctgcgag cggtgcgcct
     4441 ggcggccaag ctcggcttcc agatcgagga gggtactgcc gcgccgatcc cgcacctggc
     4501 cggcctgctc aacgaagccg cgccagcgcg cctgttcgag gaagtgctca agctgttcct
     4561 gtccggacac ggcgtggcca gcttcgaagg ccttgagcgt tacggcctgc tcgacgtgct
     4621 gttcccggaa agcgccaagg cgctgaaagc caaccgcacc ggcgcgctgc gccgcatgct
     4681 ggtcgagggc ctggccaata ccgatgcgcg ggtggccaac gacgaaccgg tctcgccggc
     4741 gttcctgttc gcgctgctgc tgtggccggg gttctgccgt gcacaggcga ccctgctcaa
     4801 gcagggcgtg gcaccggaag aggcgcagcg ccgcgccgcc gaccgcgtca ccgtgcagca
     4861 gttgagcacc atcgcgctgc cgcgccgctt ctcgctgccg atgcaggaaa tctggctgct
     4921 gcagtcgcgc ttcagctcgc gccagcgcaa gcgcgtgttc cgcaccctga cccatccgcg
     4981 cttccgtgcc gcgttcgatt tcctcagcct gcgccaggtg gcgtcgtccg agcacgccgc
     5041 cgatgtcgag ttctggcgcg aagcgcaggc gcagtccggg cgtgagctgg agtcgtcgct
     5101 ggatgcgatg cacagcgaag aaggcgatga cgagagcgga gcgccgcgca agcgccgccg
     5161 tcgccgccgt cgtccgggtg ccccggccgg tgcagcgggc gagtaggcga tgacccctgc
     5221 ctggatcggc ctcggcgcca acctcggcga cgcggccgcc accgtcggcg cggcgattgc
     5281 cgcgctggac ggcctgcccg ggacccggct gcgccaggcc tcgcggcttt acgcaacgcc
     5341 ggcctggggc aatgaagacc agctgccgtt cgtcaatgcg gtggcctcgg tcgaaaccat
     5401 cttgccggcc gatgagctgc tgcaggccat gctggcgctg gagcagcgct tcggtcgcgt
     5461 gcgcgatccg gcagtgcact ggggcccgcg cgcgctggac ctggacctgt tgttgtacgg
     5521 cgtgcaggag ctcgaccagc ccgggctgaa ggtgccacac ccgtacatgc acgaacgggc
     5581 cttcgtgttg gtgccgctgg ccgaaatcgc gccggatctg gccattcccg gccacggccg
     5641 cgtgcgggac gcagtggtgc gggtggacgc ctgcgggatt accccgatag ggtgataatg
     5701 cccgggttat ctcccccggt tatcagcaca tgagcaccca cgcagacagc aagccctgga
     5761 ccgttcccgc cctggccgag gccaagcgca atggccagaa gctggtcatg ttgaccgcct
     5821 acgactccag cttcgcccgc actttcgacg ccaatggcgt tgacctgatc ctgatcggcg
     5881 attcgctggg catggtggtg cagggccatg attcgaccct gccggtgacc gtggccgaca
     5941 tggtctacca cacccgcgcc gtggcccgcg tgctgcagcg tgcgctgctg gtggcggacc
     6001 tgcccttcgg cgccgatgcc accccggagc gcgcgctgga tgcctcgctg cagctgctgc
     6061 aggccggtgc cgagatggtc aagatcgaag gtgccggctt caaggtcgac atcatccgct
     6121 acctggtcga gcgcgagatt ccggtctgcg cgcacctggg cctgaccccg caatcggtgc
     6181 tgcgcctggg cggcttcaag atccagggcc gcggcgatgc cgcgcgccag ctggtgaaag
     6241 atgccagggc cgtggccgct gccggcgcca gcatcatggt gcttgagtgc gtgccgaccc
     6301 cggttgccgc cgaggtgacc gctgcggtgg aggtgccgac catcggcatc ggtgccggcc
     6361 cgcactgcga tggccaggtg ctggtgctgc acgatttcct cggcctggac agcggtcatc
     6421 gccgccccaa gttcgtcaag gatttccttg ccgaaggcgg ctcggtggcc ggtgccaccc
     6481 gtgcctttgc cgacgccgtg cgcgacggca gtttccccga cgaacagcac gcctacgccc
     6541 aatgatccag accttcaacg agcttggcgc attgcgcgag cagatcgccc actggaagcg
     6601 cgagggcctg cgcgtggcgc tggtgcccac catgggcaac cttcacggtg gccatcattc
     6661 cctggtgacc ttggcccgcc agtacgccga caaggtggtg gcaagcatct tcgtcaaccc
     6721 gacccagttc gggccggacg aggatttcag tcgctatccg cgtacgcccg aggccgatgt
     6781 ggccgggctg gaacaggtcg gctgcgatgc ggtgtggctg cccagcgtgg aggcgatgta
     6841 tccgctgggc gtggacaaga ccacgcgcat gcacgcgccg ggtgtcagtg aagtgcttga
     6901 aggtaccagt cgcccgggtc acttcgacgg cgtgtgcacg gtggtagcgc gcctgttcct
     6961 gcaggtgcag ccggacgtgg ctgtgttcgg ccgcaaggac taccagcagc tggctgtcat
     7021 caggcagatg gtggccgaac tgtcgttccc gatccagatc gtcggtgccg agatcgtgcg
     7081 tgacgaggat ggcctggcca agagttcgcg caaccagtac ctgagcgcgg aacagcgccc
     7141 ggtcgcgacc gccattcacc gcaccctgct gggcatgcgc gagggctacg tggccggtca
     7201 cccgcgcgaa cgcatcgagg ccgatgccac cgccgcactg caggcggccg gtttccaggt
     7261 cgactatgcg gtgctgcgca ccccggagct ggccgagccg accttcgacg gcggtggccg
     7321 cgtggcgctg atcgccgcgc gactgggtac gacccggctg atcgacaacc tggaattctg
     7381 agctccggcg gcgccgcgcg atgcatgggg tcagatgcct tttccagggg aaagggttct
     7441 gaccccggtt tcaccgccta cctgaacagg ttgccggccg tgatgccccg cgctgtgcgg
     7501 gtgctagaat ccgctctttc ctttgccgtt gcagcgcccc catgcacctg tccctgctca
     7561 agaccaagat ccatcgcgcc accgtcaccc attccgagct gaactacgaa ggctcgatcg
     7621 ccatcgatga caacctgctg gatgccaccg gcatccgcga gttcgagcag gtgcacatct
     7681 gggacgtgac caacggtgcg cgcttctcga cctatgccat ccgcgccgaa gccggcagcg
     7741 gcgttgtctc gctcaacggt ggcgccgcgc gccacgtgca ggtcggtgac atcatcatca
     7801 tcgccgcgtt cgccagcatg accgagcagg aagccgacag cttcaagccg aagctggtgt
     7861 acgttgatgg caagaaccag atcacccaca ccaacgacac gatcccgacc caggccgcat
     7921 gacaacgaac aacggattcg actcgctgca ttcccacgcc cagcgcctga agggcgcaag
     7981 catccccagc ctgctcgccg ccgaacccgg ccgcgtgcag gatctggcgc tgcgggtcgg
     8041 tccgttgtac gtcaacttcg cgcggcagaa atacgatgcc gccgcgctgc aggcgttgct
     8101 ggcgctggct gccgaacgtg atgtcggcgg cgccatcacg cgcctgttcc gtggcgagca
     8161 ggtcaatctg accgagggtc gcgccgcact gcacaccgca ttgcgcggcg acgtggtcga
     8221 tgcaccggtt gccgctgagg cctatgccac cgcgcgcgag atccgccagc gcatgggcgt
     8281 gctggtgcgc gcgctggaag acagcggcgt aaccgacgtg gtcagtgtcg gcatcggtgg
     8341 ttccgacctc ggtccgcgcc tggtcgccga tgcgctgcgt ccggtcagcg gtgcgcgcct
     8401 gcgcgtgcat ttcgtgtcga acgtggacgg cgccgccatg cagcgcacgc tggccacgct
     8461 ggatccggcg aagaccgcgg gcatcctgat ttccaagacc ttcggcacgc aggaaaccct
     8521 gctcaacggc cagatcctgc acgactggct ggggggcagc gagcgcctgt atgccgtcag
     8581 cgccaatccg gaacgcgcgg ccaaggcttt cgcgatcgcc gccgatcacg tgctgccgat
     8641 gtgggactgg gtcggtggcc gttattcgct gtggtcggcc gtgggtttcc cgatcgcgct
     8701 ggccatcggt ttcgagcgct tcgagcagct gctggaaggc gccgcgcaga tggatgcgca
     8761 tgcgctggat gcaccgctgg agcgcaacct gccggtgctg cacggcctga ccgacatctg
     8821 gaaccgcaac ctgctgggcc atgccacgca cgcggtgatg acctacgacc agcgcctggc
     8881 gctgctgccg gcctacctgc agcagctggt gatggaaagc ctgggcaagc gcgtgcagcg
     8941 tgacggacag ccggtcacca ccgacaccgt gccggtgtgg tggggcgggg cgggcaccga
     9001 cgtgcagcac agcttcttcc aggcgctgca ccagggcacc agcatcgttc cggccgactt
     9061 catcggctgc gtgcacagcg acgatcccta cacgatcaat catcaggccc tgttggccaa
     9121 cctgctggcg cagaccgaag cactggccaa tggccagagc agcgacgacc cgcaccgcga
     9181 ttaccccggg ggccgcccga gcacgctgat cctgctcgac gcactgaccc cgcaggcgct
     9241 gggcgcactg atcgccatgt acgaacacgc tgtgtacgtg cagtcggtga tctggaacat
     9301 caatgccttc gaccagttcg gtgtcgagct tggcaagcag ctggccagtg gcctgttgcc
     9361 ggcgctgcag ggtgaggatg tggcgattgc cgatccgatg acccgcgaga tactggcgca
     9421 gctgaagcgc tgagcccggt cgtggatgcg ccggcgacag gccggccatc ccatgccttc
     9481 cgttcctgcc attccggggc cctgcggcgt tgcccatgca gcgtattcgc gtgcctgcgg
     9541 cagcgcagct tgactacgca tggcgtgcca atgcagtgtg catgggcggc tgtacctgtc
     9601 atccagtatc gctcgcagca tgatgttgat gccagggact ggccgtatcc ggagggacgt
     9661 ggaatcgatc cgtgtcctca acgcctcatg ttgtgaatga caggagattg cgaatggatc
     9721 tgaatgacga cgttgtgtcc ggctggctca atggctcgga cgatgtggat gggtgcgcca
     9781 accctgcggg ttcgctgttc atctacggtg cggcagccac cgaagcggcc ctcaccgggg
     9841 cttcggacac catgatcacc ggtggcacca acgagtgcac caccacggta tcggtgatca
     9901 accactgcct gtgttgctga tgtagcccgt gccggcacgc agaggcatgc agctgcgtgc
     9961 cggcgactgg aacagactct tgaatctcgc agggggcgta atgaccgctt ctccggctgc
    10021 ggccgcgttt gcgcgcatca ccgaacattt ccttgcccag gcgcgcgctg cgctggctgc
    10081 cggcctgcat gatcccgcca tcgccctgca gcccggcgaa cgtgcgctgc tgcattcgca
    10141 gggcgaggcg gcgctgcgtg agcatgccca gctcaagctc aaccgcgtgc tcctgctgga
    10201 gctgcacgcc gctgcacgca gcggtgacat cggcccgctt gacagtgctg gtgcgctgga
    10261 cgaattcgtt gccctggcca cgagcgaggg cttccgcgcg catctgcagc aacgctatcc
    10321 ggtactgctg ccgcgcctga cgcgcatgct cgaaggacaa tgcgcggccg tggtggagct
    10381 cgctgcacgc atcggcagtg atcgtgttgc gttggccgag ttgctgggtg cgccggcggg
    10441 cacgctgcat gccgttgcat tgggccgcgg tgacctgcac ggtggcggcc gcaccgtggc
    10501 acggctgcag ttcgaaggcg gcacggtgat gtacaagcca cgctcattgc gcatcgatgc
    10561 cacgctcgat ggcctgttgt ccgcggtctt cggtgatgcc cctgaccgcg tgcgcgtgcc
    10621 gaaggtgatc gatcgtggca gccacggctg ggctgcattc gccgcgcatc gctattgttc
    10681 cggcgaggct gaactgcggt gctattaccg cggcctcggc cactggctgg ccatcctgcg
    10741 cctgatcggt ggcaccgaca tccatctgga gaatctgatc gcggtcgggc cggtgccggt
    10801 ggtggtcgac gccgaaagcg tgttctgccg ggtaatcgaa atcgagccat cagggcttgg
    10861 cgatgcgtac gacaccgccg tcaagctgat gcgcaattca gtgctgcgta ccggaatcgt
    10921 gccgttccgt actgccggcc tgggcatgga gggcgtggac ctgtctgcag ccggcgcgct
    10981 gcccggcgag cagccacggg tgcaggtgcc ggtgatcgtc gacgacggga ccgaaccggc
    11041 ccggttgggc atggtcgagg ccgaggtctc cattgcgcag aaccatccca gcgcacagcc
    11101 cgatgtgtcg ttgtactggg accacatcag cgagggcttc atcgacgcca gtgggcgtct
    11161 gcgcgcgctg gacgcgaacg gcgaactgat gccgctgctg acggccttcg aaggctgcca
    11221 ggtgcgggat gtacggcggc cgacaatggc ctacgccgag ctcgggcgga tgctctggca
    11281 tccagcatcg cttcacaacg aagctcgggc ggttgagcgc gcgatcgacc tgctggtgcg
    11341 gaatgcggcg gtgtcgcccg ctgcgccatc ggacctggaa accgtacgcg gagaggtcga
    11401 tgacctgcgc cacggtgaca ttccgatctt cgcatcgcag ctggacgcgg cgcgtatcca
    11461 ctccgtcgtc gccaactggc gcgcgatgcg gatcgacctg gaagacgtga cgatccgcag
    11521 cacgctggtc gccaccgacc tgaaccagca tgcactggcc cgagccgagg cccggtccgg
    11581 ctacagctat gcagcacggc atccgcgcgc cgacgacctg gacgcacgcc gtcgcacgct
    11641 ggccacgcgc gcggtggaaa gcctgctgcg gctggcggtg cacggcgaag acggctcgat
    11701 gacctggatc acacctgaag tgacgcgtac cggatggacc gtccagccgg tgcagccaga
    11761 cctgtacttc gggctgggcg gcatcgcttt cgcactggca gcctatcgcc acgaagtgga
    11821 gcaggggcgt gccgatccgg tggccgggct ggatccggcc atcgagggcg cccttgcggt
    11881 gttccagacc ctgtgcgagc ggcaccccgc cgaaattgac ggtggattcg ttggaaccgg
    11941 ttcgcaaatg tgggcattgc tggcattgca cgacctgttg cagcgaccgg cgctgctggc
    12001 gctggcagag cgctgcgcgg aagccgcgga gcatcgcggt ttccagcagg cggcaaagtt
    12061 cgaactgatt gatggtgtgt ccggcatgat cctgccgttg ctggcgctgg ctgaagccac
    12121 cggcaacgca cgctggctgg aactggcggc cgcagcggga cgccgcatgc aggacgctgc
    12181 gattgtcgac gcagacggtg cgcgctggcc gacgccacag ttcagcgagc cgatcggtgg
    12241 ttttggccac ggtgcgatgg gcatgggctg ggcgctggca cgactggccc gctccgaggc
    12301 tggcagcgtg cccgagcggg ccgcatggtg gcggctggcc gaaggagcat ttgcattcca
    12361 ggcagccctg ttcgagccac ataccgggca ctggcgggac atccacctgc aggatgggca
    12421 gaagaacttc ccgacctggt gccacggcag cgtgggcatc ggcctggcgg cggcggacct
    12481 gtatgcccgc accggtgatg ccgcgcaatt gcgcgacatg cgtcgcgccg tggccgatgc
    12541 gcgcggcaaa tgggggttca gccacaccct gtgccatggc gatgtgtcca cccgggaact
    12601 gctggtgctg gccgctgcgc tggatccggc agggtgtccc tatccgcagg acgaggccgc
    12661 catcgagatc atttcttcga tcgaggagca ccaggggatg gttggcggcc tcacccgcgc
    12721 ggcctttacc ccgggcctga tgatcggcct ggcgggttcg atctacggct tcctgcgcat
    12781 gcatccggcc tgcgtactgc catcgccgct gctgcaggag acgatggcca cgcgggccga
    12841 tgcgtgtgcg gtgcgctcca gcgccgcgca ggaccggccg gcgctggtcg aggcctgagc
    12901 cggaccggtc cgtcagcgat caacggctcg gatcgcgttc cgggctcggc cgctttgcca
    12961 gcttgcgctg cagcgaacgc cggtgcatgc cgagcaggcg tgccgctgcg gacacgttgc
    13021 cgccggtctc gtgcatcgcc tgctggatgt gttcccactg caggcggctg atcggcgtca
    13081 tcgcgtccgg cacttccatt tcgccatcgt cggccgggcc gtcgtcttcc tcgccaagcg
    13141 cgcgcaggat catcggtacc gtggccggct tcggcaggta atcgtcggcc cccagcttga
    13201 tcgcctcaac ggcagtggcg atgctggcgt agccggtcac cagcaggata cgcatgtccg
    13261 cgcgcagcgc gcgcagcggc tggatcagcg ccaggccgga atcactgccc agcttcaggt
    13321 cgatcagcgc gaacgccggc ggatgctggc gggccaatgc cagcgcgctg gcggcatcct
    13381 gcgcggtctg cgtttccagt cccttgcggg ccaggctgcg ctgcagggtg cgcaggtaca
    13441 gttcgtcgtc gtcgaccagc aggccgaggg ttgaggcgct catggggttt cctcgcgtgg
    13501 gaccagcggc aggcggaagc cgacgcggct gccggcgcct tgggccgggc gcatccacat
    13561 ctcgccgtcg aggcgttcga tggtggcatg ggacagggcc aggccaacgc ccatgccctc
    13621 gctcttgctg ctgccgaaca gcttgcctgg cagcaccgcg gcacgggcat cgaagccgtg
    13681 gccgtagtcg cggacttcgc cgatcaggtc gtcgccttcg atgcgcaggt ccaggtctac
    13741 ccgtggccgc ccggcctgtt cgccggcatc tgcggcattg ttgagcagga ccatcagcag
    13801 atggcccacg cccggatcca gtggtaaccg cagcggcgca tcgtcattgc gatgcaggtc
    13861 gatggtcggc cgcaccaggc gccactgttc cagtacctgc tgggcgctgg agtggctgcg
    13921 gcccggtgcg tcggccgagg ccggtgcggc cagcgccagc acgcgttccc ggcactgcac
    13981 cagcagttcg cgcagggtct ccatgtcttc gcgcacttcg ggctcttcgc tgcgctcggc
    14041 gacgtcatcg gcaagcaggg tcatggtcgc cagcggcgtg ttcagttcat gcgccacgga
    14101 ggcggcatgg gtggccaggg cgacgatgcc ttcgttgcgg gcgaagcgtt ccctgagtgc
    14161 cgacagttcc agttcgcgct gtcgcagcgc cagcgccagg cgggtggaga aggtcagcac
    14221 gaccgctgcg gaaatgagga agttggcgac cacgccccaa cggttgaggt cctgcgcgcg
    14281 gaaatagccg tccggcagcg gctggccgaa gatgccgctg gcggcgtagc cgagcaggca
    14341 ggccagggcc actgccagtg cccagcgcag gggcagggcg aaggcggcca gcgcgatcag
    14401 gatcaggaac agtgaactga acgggttggc catgccgccg ctccagccca ccatccaggt
    14461 caggatgatc acgtccacca ggatatggcc gaatgcggtc agcggggcgg tgtcggccgc
    14521 ttccgggcgc agctgggtgt agatgttgaa caaggtgagc acggccacgc cggcccatag
    14581 tggcagctgg ggcaacggca ggcccagtac ccagctggcg accaggatgg tggcggcctg
    14641 gccgcctacg gcaagccagc gcaggctgca cagggtacgg aggaacgggg cgtcgggacc
    14701 ggtcattcat gctcatcgta tgcgttcacg ggcgcgcgtg cctgcgacaa tcggccgcag
    14761 ccgtgccgcc ggctgaatgc gagtcacccc gaatgcggga gcgggcggta gaatgcgccc
    14821 atgcacgacg ccgtgacccg ccctacgcct ccctccgatg ccacctcctg gccccgccgc
    14881 cagacccatg ccgtgcagat cggcggggtc accgtaggcg gaggcaagcc ggtagtggtg
    14941 cagtcgatga ccaacaccga cacctccgac gtggcttcca gcgtcaagca ggtggccgag
    15001 ttgtggcgcg cgggttcgga aatggtgcgg ttgaccgtca acaccgtgga agcggctgcg
    15061 gcgatcccgc gcatcgtcga caagctggcg atgatgggta tcgacgtgcc gctgatcggt
    15121 gacttccatt acaacggcca ccagctgctg accgccgaac cggcgtgtgc cgaagcgctg
    15181 gcaaagtacc gcatcaaccc cggcaacgtc ggcttcggca agaagaagga cctgcagttc
    15241 gcgcagttga tcgagtttgc gatccgctac aacaagccgg tgcgcatcgg cgccaactgg
    15301 ggctcgctgg accaggccct ggcggcgaag ctgatggacg agaacagcct gcgcgaacag
    15361 ccctgggatg ccggccgcgt gctgcgcgaa gcgctgatcc gctcggccct ggattcggcc
    15421 gagcaggcgg tggaactcgg cctgccgcgc gaccgcatcg tgctgtcggc caaggtcagc
    15481 ggcgtgcagg agctgatcgc ggtataccgc gacctggccc agcgctcgga tttcgccctg
    15541 cacctgggcc tgaccgaagc cggtatcggc agcaagggca tcgtcgcgtc ggcggcggcg
    15601 ctgggggtgc tgctgcagga aggcatcggt gacaccatcc gcatctcgct gaccccggaa
    15661 ccgggccagt cgcgcacgca ggaagtgatc gtcgcccagg aactgctgca gaccaccggc
    15721 caacgcgcct tcacgccgct ggtcacggcc tgcccgggct gcggccgcac cacctcggag
    15781 ttcttccagg agctggccaa ggtcgtgcag aaccacgtgc gcgagaagat gccgctgtgg
    15841 aagatccacc acccgggggc ggagaacatg accctggcgg tgatgggctg catcgtgaac
    15901 gggccgggcg agtcgcgcca tgccaacatc ggcatctcgc tgccgggcac gggcgaaaca
    15961 cccgcagcgc cggtgtttgt cgatggcgag aagaaggtga ccctgcgcgg cgacaacatc
    16021 gcccaggagt tcgtcgccct gatcgacgac tacgtcgaac acacgtatgt ccgaagcgcc
    16081 ggataagcct gcgatcctcg ctgcaccgga atccgcctcc ggtttccgcc actggatggc
    16141 gcgcaatgcc tggcgtctgg tcctgctgtt cggcggcgtg ctgctgccgc tggctggctt
    16201 cgtcgccctg gcggacgagg tgcacgagtt tgaatcgttc catttcgacg cgccgctgct
    16261 gtggcagatg catggcctgc actcgccact gctggaccgc ttcttcgtgc tcatttccaa
    16321 actgggctat gagtggttcc tgatcccggc cgacgtgctg atcatcggcg tgctgctggg
    16381 ctaccggcgc tggcgcgagg ccaccttcgt ggcggtcagc ttcgtcggct cggcgctgct
    16441 gaacatgggc agcaagcact tcttccagcg ccagcgcccc agcctgtggg aatcgatcgc
    16501 gccggaatcg acgttcagct ttcccagcgg ccacgcgatg ggctcgatga ccctggcggt
    16561 gaccctggta ctgctggcct ggaacacccg ctggcgctgg ccggtgctgc tgctggcacc
    16621 ggcattcagc ctgctggtca gcgtctcccg ggtctatctg ggggtgcatt acccctccga
    16681 tatcctggcc ggatggtgtg ccgcgctggt ttgggtggta gggtgctatc tggtcatgtt
    16741 cagtcaccgg cacccttggc ggcatcatgg cacgcggcca gcgaaggcca gcgaagcatc
    16801 atcacagggg gattgacgtg gatgccccgc gcgggacgtc tacgtgatag atcagttgtt
    16861 tcgttgcagc aggttctgca agacaggggg caagcacaac gcgcggtact gtgatgcgca
    16921 aggcagattg ccggggccgc attccgaacg cgcttgcagg gtatcggcac cctgcctagc
    16981 ttgacctgca atggccgcat tcgaagaggt acgtgaatga cgattcgagt ctacctggtg
    17041 gatgaccacg cgctggtccg caccgggatg aagatgattc tgtcggggga aaccgacatc
    17101 gaggtggtgg gcgaagccga gaccggcgaa gacgcgctgc gtgaagtccg ccagctgctg
    17161 ccggatgtgg tgctgtgtga cctgcacctg ccgggtgtga gcggcatgga agtgaccgag
    17221 cgcatcgtgc gcagccaccg caacacccgc gtagtgatcg tgtcggtgct ggaagatggc
    17281 ccgctgccga agcggctgct cgaagccggc gcggccggat atatcggcaa gggttgtgat
    17341 gcgcaggaac tgctgcgcgc ggtgcgtgac gtggcaggtg ggcgccgcta cctgggcacc
    17401 agcatcgcgc agaatctggc actgtcgacg gtggaaggca acggttcgcc gttcgacagc
    17461 ctgtcgccgc gcgagctgga agtggcgttg ctgctgaccc agggcctgcg ccaggaagat
    17521 atcgcgcggt ggctgagcct gagtgcgaag acggtgaaca cgcacaaggc gcggctgttc
    17581 gagaagatgg ggatccacga caacatcgcg ctggcgcgga tggccagcca gtacgggttg
    17641 gtggatccgg cgcggccgct gtaacgggtt tcggccaacg gctgagcccc ttgcggtgtg
    17701 cggcaggatt cgtggggttg gccctgcgga gggattgcgc aggggacgcc gtgaatccat
    17761 ccctggaggc tcggtcgcgc catccatggc gctcacgccc ctgcgcaatc cctccgcagg
    17821 gccaaggacg gttttcgtgc gccgccaccg cggaatgaag aaggaagagc gggagcgggt
    17881 cgcgctctgg atgctggtcc tgtagagctg agccatgctc ggctgctttc cattccgctg
    17941 gcgtggagcc gagcgtgggc tcggctctac agctgcgttg cgctcagtgg tcgcgaacgc
    18001 gcttgatgat cttcgcggcg tcggcggcgc tggcgcgcac cttgtcccat tcgccgttgg
    18061 caatccagtt gcccggcacc atccacgaac cgccgatgca gaccacgttt ttctgctcga
    18121 ggtattcggc ggcggtgttt tcggtgatgc cgccggtcgg gcacagcttc aggtccgcca
    18181 ccgggccggc cagtcccttg atcatcgcca gcccgcccac ggccgtggcc gggaacagct
    18241 tgcacacgcg gaagccgcgg gcgtagagcg acagcagctc ggtcggcgtg gccgcacccg
    18301 gcaccaccgg cagcggcgca gcagccagtg catcggccag cgctggcggc gtgcccgggg
    18361 tcaccaggaa gtccgcgccc gcatcgatcg actgctgcat ctgctccacg gtcagcaccg
    18421 tgcctgcacc caccaccaca tcgggcagct cgcgcttgag catcgccaac gcttccatcg
    18481 ccaccggcgt acgcagcgtc agctcgatcg ccggcaaacc accgtccagc agcgccgcac
    18541 tgaccgcccg cgcctggtcc agcgtatgaa ccgtcaccac cggcaggatg cccgccgcat
    18601 gcaacagctc cgccgccttc acctgatgtt gttcgatacc catgcttttg cccttgcctt
    18661 tgctcttctt gattcagtgg ccgcagcgca aatgacgcgc cgggaattgt ccaagggcag
    18721 tggagtgccc tggccgggac cgtgagcggc atggatgccg cgatcgagcc cccatggatg
    18781 ggtttacggc gtgtcccggc cagggcgctc tactgcccaa gccgggaagc ctgccgcggc
    18841 ttttcgcttc aggcgtcttt cgcctcatgc ggcgctgccg ccgccgcggc atcatgcccc
    18901 agctcgtact ccgcgtcgta ctcccacggc ccgccatcgg ccgccgccgg accgcacgaa
    18961 atcgacatcg ctccctggtc ggccgggccc accacgcgac ggttgaccgc gaacagattg
    19021 cggcccaggt catgcgcggc cggcgcagtg ttcggagcca gcggacgcgc cgcccattcg
    19081 gccgggtcca ccagcacctc cagcgtgccg gcctcgccgt ccagccggat catgtcgcct
    19141 tcgcggacct tcgccagcgg gccgccgcgc gccgcttccg gcgtcacgtg gatcgccgcc
    19201 ggaatcttgc ccgaggcgcc ggacaggcga ccgtcggtga ccagcgccac gcgtcggccc
    19261 tggttctgca acaggcccag cagcggcgcc agcgaatgca gttccggcat gccgttcgca
    19321 cgcgggccct ggtaacgcac caccgccacg aaatgctcgg gcagcaggcc accggcgtgc
    19381 agcttgttca gcacctgcgg tgcatcgacc accacggccg gtgcttcgat cgtgcggtac
    19441 ttcggcttca ccgccgacag cttgatcagc gacttgccca ggttgccgcg cagcaggcgc
    19501 aggccaccct ggtgttcgaa cggattgtcg acgccacgca ccacctcgtc atcggcgctg
    19561 cgttccaggc ccggcagata aaccagttgg ccgtcgcgca gctggggttc gcgggcgtag
    19621 tcggccatgc cgccacgggc cacgctgacc aggtcgccat gcatcaggcc ggccttgatc
    19681 agctcgccga acacgaacgc cgggccaccg gcggcggcga agcggttcac gtcggcctcg
    19741 ccgttcgggt agacgcgggc cagcagcgga atcagctgcg acagctcgtc gaagtcgtcc
    19801 caggtcagca cgatgccggc cgcacgcgcc accgcgatcc agtggatggt gtggttggtc
    19861 gaaccgccgg tggccatcag cgcgatgacc gcgttgatga tcgcgcgctc gtcgatgatc
    19921 cggcccagcg gacggaagtc atcgcccagc gcagtgatgt ccagtgcacg ttcggtcgct
    19981 tcgcgggtaa gagcgtcgcg cagcggggtg cccggattga cgaacgacgc gcccggcagc
    20041 tgcacgccca tcgcttccag cagcacctgg ttggagttgg ccgtgccgta gaaggtgcag
    20101 gtgccggcgc cgtggtagga ggccgactcg gcttccagca gttcttcacg ggtggcttcg
    20161 ccggcggcat agcgctcgcg aacttccgcc ttctgcttgt tgggtatgcc cggggtcatc
    20221 gggccggccg gcacgaacac cgccggcagg tggccgaagg ccagtgcgcc gatcagcagc
    20281 cccggcacga tcttgtcgca gacaccaagg tagacggtgg tatcgaacat gtcgtggctg
    20341 agcccgatcg ccgtcgcctg cgcgatcaca tcgcgcgaga acagcgacag ctccatgcca
    20401 ccacggccct gggtgacgcc gtcgcacatc gccggcacac cgccggccac ctgcgcggtg
    20461 gcgcccagct cgcgggcgat ctggcggatc tgctcgggat aggtctcgaa cggctggtgc
    20521 gccgacagca tgtcgttgta ggcggtgatg atgccaaggt tcggtgtcac cccaccgcgc
    20581 aggcggctct tgtcggtgcc gccacaggcg gcgaatccgt gggcgaggtt gccgcagctc
    20641 aggcggctgc ggaacgggcc ttcgcgcagg gaggcgtcga tcgcggccag ataggcggcg
    20701 cgcgaggccg cgctgcggcg gatgacgcgc tcagtgatgg cttgcagttg cggatggagg
    20761 ctcattggct accggcgttc gtggtggcga gaggcaagcg gcggcgtggc gccgccgccg
    20821 acatcaatca gcccagtgga cgcgcaggcg cgcgccttcc aggttgattg cattgaggat
    20881 cgggtactgc tgggggtcat tgctgtccag tgcctggcgc agtacctgca gcttctgctt
    20941 gccgcgcagc agcagcagac gctggcggca ctggcgcagg ccgtgcgggg tcagggtgat
    21001 gcgcagcggc cactggttcg cgcccgggca gccggtggca tccagtgccg catagggcag
    21061 ggtgctttcc agtgcacggg ccaggtcctt cgaacccggg aacagcgagg cggtgtggcc
    21121 atcgttgccc atgcccagtg ccaccaggct gggtggctgg ctgtgctggg cctgcaggtt
    21181 ggcggtgtag acgcactccg tcagcggctt gccgatccgc accagcggat cgaagtgcgc
    21241 accctcggca cgcttgagca ggtgctcgcg caccagccag gcgttgctgt cgcgatcctg
    21301 cggcgacagc caccgctcat cggccaggct cacttccacc cggtcccaat gcacgtccag
    21361 ttcggccagt gcctggtata ccggcgccgg cgtggtgcca ccggagagca ggatgcgggc
    21421 ccggcccacc tcattgatgt cgtggttgag ggtctgcgcc atttcggcgg ccaccgcctc
    21481 gatccagcca tcggcgtcgc cgtgctgaat gaactcgatg cggtcgtcgt gcaaggtggg
    21541 gctcatgcgg caactcctgg tgcgtcacgt tcggcgtcgg cagcataggc ggcagcgccc
    21601 agcagtccgg cgtggggatg catcacggca agcgatggca ccctcgccat gatcgaagag
    21661 aaccgcccct tgtgttcgaa gcgctggcgg aagccggagt gctgcagtga atcgagcatc
    21721 ttcggggtca ggccgcccgt caggaacacg ccgtcccagg cgccctgggt cagtaccaga
    21781 tcgccggcga tggcgccgaa caccgcgcag aacacgtcca cggtgcgcat tgcctgcgga
    21841 tcaccgtgca gggcacgcgc ggtcacgtct accggctgca gctggccggg gtcgatgccg
    21901 gccatctcgc acacggcgcg atggatgttg accagcccgg gtccgcagat caggcgttcg
    21961 ttggagacgc ggccgaactg ctcggagagg atttccagga tgcggatttc ctccggtgtg
    22021 cccggtggga aactgacatg accgccttcg gtttccagcg gatagcagcg gccgtggcgc
    22081 atgatcaggc caccgacgcc gagcccggta ccgggcccga tcaccgcgta gttgcgcggc
    22141 tgtcccggct tgcccggtac ccaggcggcg ccgccgacct ggacgacgtc ctcgggctgc
    22201 agcagcgaaa tcgccatcgc ctgtgcggcg aagtcgttga tcaggtgcag ctcgtcgaac
    22261 cccagcatcg cggcggtgcg gctgcgcgag atcacccacg gatgattggt gatgcgcgcc
    22321 tcgtcaccgt cgacgcggcc ggccactgcg aacacgccgc ggctggccgc agcgccgatc
    22381 tgctccaggt ggtggcgcgc ggcatcaccc agcgacggga attccgccac cgcgtactcg
    22441 cggatgctct ccttgagcag cggcgcgtcc tgcgaggtgt cggccagggc gaagcgggca
    22501 ttggtgccgc cgatgtcggc aaccagcacc ggctgcgaga tggcactcat gccgaggccc
    22561 cgctgtccgg cgcgtccacg ccctgcggca ggaactcgcc tgcattgctc gggccccact
    22621 ggccagcagg atacggttcc agcggcagct tggcctcctt ccaggcgtcg gcaacgctgt
    22681 cgatccaggc ccacgctgcg cgcacttcgt cgtcgcgcac gaacagcgtg tggttgccgt
    22741 tgaaggcatc caggaacagg cgttcgtagg cgatgcggcg gtgcaggccg gtcggcaccg
    22801 acagttccag ttccagcgga tgcagttcca gggcacccca ttccgggccg gccaggctgc
    22861 tcatcaggcc cagttcgatg ttttcctgcg gctgcagc
//
