LOCUS       NZ_KB907498            10846 bp    DNA     linear   CON 21-MAY-2024
DEFINITION  [Pseudomonas] hibiscicola ATCC 19867 G370DRAFT_scaffold00001.1,
            whole genome shotgun sequence.
ACCESSION   NZ_KB907498
VERSION     NZ_KB907498.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      [Pseudomonas] hibiscicola ATCC 19867
  ORGANISM  [Pseudomonas] hibiscicola ATCC 19867
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 985584)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name :: Stenotrophomonas maltophilia ATCC 19867
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: ATCC 19867
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. R37654
            finishing_strategy                :: Missing
            environment                       :: Host
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi15375
            Type Strain                       :: No
            Funding Program                   :: DOE-CSP 2012
            Isolation Site                    :: Plant
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. R37654
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000382065.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 01:07:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,084
            CDSs (total)                      :: 4,007
            Genes (coding)                    :: 3,964
            CDSs (with protein)               :: 3,964
            Genes (RNA)                       :: 77
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 15 of 43
            Pseudo Genes (incomplete)         :: 31 of 43
            Pseudo Genes (internal stop)      :: 7 of 43
            Pseudo Genes (multiple problems)  :: 7 of 43
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:56:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 686981
            Orig. end                         :: 697827
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB907498.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 408460
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Nikos  Kyrpides (nckyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-PGF and JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10846
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10846
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10846
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5846](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5846
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(563..574)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            complement(1255..1995)
                     /db_xref="GeneID:90524445"
                     /locus_tag="G370_RS0103375"
     CDS             complement(1255..1995)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90524445"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659345.1"
                     /locus_tag="G370_RS0103375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_019659345.1"
                     /transl_table=11
                     /translation="MNHVPHILVVDDDSEIRQMLADYLQRNGLRVSQADGGRAMRALMD
                     THAVDLVVLDVMMPGEDGLSLCRNLRAGKHRAVPVVLLTARDDETDRIIGLEMGADDYV
                     TKPFSSRELLARINAVIRRTQMLPPNLQVSEAGRQLAFGEWRLDTTARHLLDAQGTAYP
                     LSGAEFRLLRVFLDHANRVLSRDQLLSLTQGRDAELFDRSIDLLVSRVRQRLGDDAREP
                     TYIKTVRSEGYVFSLPVQLLGPDE"
     gene            complement(2053..2598)
                     /db_xref="GeneID:90524446"
                     /locus_tag="G370_RS0103380"
     CDS             complement(2053..2598)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90524446"
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005415663.1"
                     /locus_tag="G370_RS0103380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="redoxin family protein"
                     /protein_id="WP_019659346.1"
                     /transl_table=11
                     /translation="MAALRVCALPLLLSLLGGAALLMAWRSPEADAQPAQAVPAAGFDG
                     GGPWHNSPPLTLKQLRGQVVLVEFWTYTCSNCLNVAPYVHRWHARYAPQGLRVIGVHTP
                     EFAHEGLPGNVRKAIARLDITWPVVQDNQYRIWNAWRNRFWPALYLLDRQGRVVYRHYG
                     EGDYARTESEIQRLLASP"
     gene            complement(2602..3390)
                     /db_xref="GeneID:90524447"
                     /locus_tag="G370_RS0103385"
     CDS             complement(2602..3390)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90524447"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408502.1"
                     /locus_tag="G370_RS0103385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_019659347.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.4e-15, bitscore:
                     53.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTCLLAAALALAAAPAFAAQADTVAPPTVILVHGAFADGSSWS
                     KVISTLHDWKLPAVAVQNPLTSLADDVAATRRAIAAAPGKVVLVGHSWGGTVITEAGND
                     PKVQALVYVAAFAPDAGQSSAQQGEGFPVGPGLARLQERDGYLTLPADAVAQDFAPDVM
                     KKSAALLYSTQVPLKASALGEVVNVAAWRSKPSWYVLSRDDRMLSPQLQAATAKRIGAQ
                     LQSIGSSHVSLLSHPAQVADSILEAAGVKPAELPLAEQGG"
     misc_feature    3611..3629
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.64"
                     /tool="antismash"
     gene            3733..4377
                     /db_xref="GeneID:90524448"
                     /locus_tag="G370_RS0103390"
     CDS             3733..4377
                     /codon_start=1
                     /db_xref="GeneID:90524448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479418.1"
                     /locus_tag="G370_RS0103390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DoxX family protein"
                     /protein_id="WP_019659348.1"
                     /transl_table=11
                     /translation="MISTASSVYTPRLDAVGRWLSPLALRTLLAWEFFESGREKLGGQN
                     WFADLEGRFPFPFSTLPASLNWQLATWLELVGAVMLLLGLATRSVAYVFWVLTIVAIAA
                     VHWPDQWNGLGELWQGYAITDQGYGNFKLPLLFLAMLLPLILNGGGALSVDRLLAGPGR
                     ATAGNDGLGWGVSLIALLLPVAALLPGIGFGGALLGGVLLLGHLLRCRRAA"
     gene            4473..4946
                     /db_xref="GeneID:90524449"
                     /locus_tag="G370_RS0103395"
     CDS             4473..4946
                     /codon_start=1
                     /db_xref="GeneID:90524449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412584.1"
                     /locus_tag="G370_RS0103395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_019659349.1"
                     /transl_table=11
                     /translation="MSISTKNTSSSRLPRIGAIGIALAGGLLLAGQAAAIQPLAISAVA
                     MSAAEGKCGEGKCGANKATTGKPAGKAKVAEGQCGEGKCGDASFARTDRDHDGKVSRAE
                     FNAVAAKRAAEFDRIDTDHDGYISEQEAHDYLRSVYTANGKPMPKGLFSRVAD"
     misc_feature    complement(4488..4502)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.48"
                     /tool="antismash"
     misc_feature    complement(4962..4971)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            5001..5846
                     /db_xref="GeneID:90524450"
                     /locus_tag="G370_RS0103400"
     CDS             5001..5846
                     /codon_start=1
                     /db_xref="GeneID:90524450"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646321.1"
                     /locus_tag="G370_RS0103400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_019659350.1"
                     /sec_met_domain="DUF692 (E-value: 4.8e-120, bitscore:
                     395.6, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLPLPTHAAGLGLRRGLIDELLAMPAGAIDFLEVSPDNWIGVGG
                     AHGDALRQLSERHPLTCHGLSLSLGGPDPLDRTLLAQTRAFLDLHQVQLYSEHLSYCAA
                     GGHVYDLLPLPFTAEAVHHVAGRIAQVQDMLGRRIAVENISYYAVAGADMSEIDFINAV
                     LAEADCDLLLDVNNVFVNACNNGYDAFEFLARVPSHRVASLHVAGHFDEDDGFKIDTHG
                     APVKGVVWALLREAYARLGVRPTLLERDFNFPPLAELLAEVAHIRQAQVEARWQEVAHG
                     "
     gene            5839..6609
                     /db_xref="GeneID:90524451"
                     /locus_tag="G370_RS0103405"
     CDS             5839..6609
                     /codon_start=1
                     /db_xref="GeneID:90524451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646320.1"
                     /locus_tag="G370_RS0103405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_019659351.1"
                     /transl_table=11
                     /translation="MAESLAIVQRRWADHVRDPSMPAPDGVEARRMAVYRRLCIDSLDT
                     LLAGSLPRLLEQLGEARWRGLVERYYAHHVCHTPLFPQIASEFAAWLAVQYAFALPGWA
                     AELAHYESTQQTLHIVARDAGHSLQSMPAGSDVLALSPLVRVLGYRWPVHEDAALDDAA
                     ASDPTLLLLRRLADYQLQVEELAPLAYALLSAFADDGTHVDDALNALADAHGVAADELR
                     VVATPLLGELCAAGVLVTLAGFCDCRPAAGTTPV"
     gene            6624..7262
                     /db_xref="GeneID:90524452"
                     /locus_tag="G370_RS0103410"
     CDS             6624..7262
                     /codon_start=1
                     /db_xref="GeneID:90524452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408497.1"
                     /locus_tag="G370_RS0103410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="WP_026346951.1"
                     /transl_table=11
                     /translation="MAASNTSFLHGWRLFVTMAVVLIAVALAAFTLQPDVVEGSRAAIR
                     VTARTSFLLFLAAFTASSFASLLPGPFTQHMLRERRIIGLSFAFSHLLHAVAITAFGIL
                     NPAFWPARSALANLPGTIGYVAILALAITSYRGIARRMGPTVWRRLHVTGMWIIAAVFT
                     YSYFKRVPGNFWYAVPSALLFTAVVVRAIAKRAQSLRRNAHARPPLRSS"
     gene            complement(7398..8534)
                     /db_xref="GeneID:90524453"
                     /locus_tag="G370_RS0103415"
     CDS             complement(7398..8534)
                     /codon_start=1
                     /db_xref="GeneID:90524453"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004147841.1"
                     /locus_tag="G370_RS0103415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metallophosphoesterase"
                     /protein_id="WP_019659353.1"
                     /sec_met_domain="Metallophos_2 (E-value: 3.9e-09, bitscore:
                     32.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAVLSTIGLLMGLYVAWRLFWPLRMPPWQKVVLSLLLVGVAVQL
                     RIVATFWGTMASPEIPKLAIATLATGSTAVLLLALLMLAMDAGLLASRLLLWPRAVAAL
                     RTRRLRPAAGVLALLVSGYGVSQGMAVPHARQIEVSIAGLPAAFDGYRVLQLTDIHASR
                     LLTGDWVRRVVAESNALKPDLIVITGDLIDGSVEARRDDARPLADLHAPDGVIAITGNH
                     EYYAQYQAWMQAFRALHMQVLENSHLQVRRGDAALTIAGVTDPVAARYGLPLPDLQAAL
                     EGADPSAPVILLDHRPRNAREAAARGVKLQLSGHTHGGQIIGMDQLVKRANGGFVSGRY
                     DVDGMTLYVSNGAGLWAGFPARIGVSSEITLITLRRAP"
     gene            complement(8657..10198)
                     /db_xref="GeneID:90524454"
                     /locus_tag="G370_RS0103420"
     CDS             complement(8657..10198)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90524454"
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659354.1"
                     /locus_tag="G370_RS0103420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TerC family protein"
                     /protein_id="WP_019659354.1"
                     /transl_table=11
                     /translation="MEWLADPSIWMGLATLVVLEIVLGIDNLVFIAILADKLPPHQRDR
                     ARVIGLALALLMRLVLLAALAWIMKLTAPLLTLFDHSFSGRDLILLGGGLFLLFKGTME
                     LHERLEGREHHEDGKKVYASFAMVVAQIVVLDAVFSLDSVITAVGMVDNLGVMYAAVTI
                     AMALMLLASKPLTRFVNKHPTVVVLCLGFLLMIGFSLVAEGLGYKIPKGYLYAAIAFSI
                     LVEAFNQWVRFNRERNERRLPFRQRTADAVLRMLGARPANGHDDEGGDGQVDTAERLQP
                     AEHEMIRSVLGLADRPVSSVMTVRADVQWIDLARGQEDVVARLVASPHTRLLVGEGDLD
                     SLRGVVQSRDLLADLLQGRPLQLEGNLREPQYVLSSASALQALELIRQHPVPLAVAVDE
                     YGSVEGLVTANDLLAAIAGDLVDTQDERYGVVAQGEDQWEADGALTLDDLQRLAGVSLP
                     RSADYMTISGLVLEQLGRLPDIGDVVEVAGVRITVLAMEKRRIARLRVQRLDGMA"
     gene            complement(10242..10466)
                     /db_xref="GeneID:90524455"
                     /locus_tag="G370_RS0103425"
     CDS             complement(10242..10466)
                     /codon_start=1
                     /db_xref="GeneID:90524455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479411.1"
                     /locus_tag="G370_RS0103425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_019659355.1"
                     /transl_table=11
                     /translation="MAIVITLDRMLQERGMTLSELAGRIDITLANLSILKTGKARAIRF
                     STLDAICRELQCTPGDLLGHDPAQAHDAD"
ORIGIN
        1 tcagcgaacc acccagcgac tgcgccagct gcaccgcgat ggccagtccc agaccggtcc
       61 ctccggtatc gcggttgcgc gagctctcca gccggtggaa cggtgccagc actgcctgca
      121 gctggtcctc gggaatgccg gggccacggt cggaaatgct gatccacacc cttccggccg
      181 tatcgcggcc cgcctcgatc tcggcggcgc cggcgtagcg caatgcgttg tcgaccagat
      241 tgccgaccac gcggcgcagc ggctgcggcc aggtctgcac gaccagtcca gcgggcgcac
      301 cgccagtgac cggcttgccc atgtcctcgt agtcgccgac cacactggcg aggaacgcgc
      361 ccaggtccat cgacaccggc gcgccagcgg caacgtggct gctgcgcgca taggccacgc
      421 cctcacgcac cagctgccca aggtgatcga ggtcggccag caggcgctgc tgggtgctgt
      481 cttcaggcag ggtctccacc cgaagcttca tgcgcgtgat gggggtctgc aggtcatgcg
      541 agatcgcggc caggatctgc aggcgttcac tgacatggcc acgaatgcgt gcctgcaggg
      601 cattgagtgc ggctgctgcg ccgcctactt ccgcagggcc atcttcaggc agtgcaggcc
      661 cgtccttgcc cggctgcaga tgctccaccg catgcgacaa ctgctgcagc gggcgcatgg
      721 ccagacgcac tgccagccac gcgcacacca gcagcagcgc cagctgcagc agcagcacgg
      781 cgggcagcca acgtgccagc ggcaggcccg acggggtgac ttcaatggtc aagggtgtgc
      841 cgtcgtgcag gcgcagttcc acctcgaacc gctccggcag gcgagccacc tggcgcgcct
      901 gcaacggata gcggtgctgc aggctgtcgt cgatgatcgc cgtgacctgg cgtgcacgat
      961 cggtctgcag ccctggtccg gccgcggccg ggcgcagcag atagcggtag gtgcgccgct
     1021 ccagccgcgg cacccaggcc tcacgctgct ccgcaggcaa atgttccagc agcgcgacgc
     1081 tcactgccac atcctcgtcg aggttgcgca gcatcatgct gcgggtggac tggtagcgtt
     1141 cgaagaacag caggccgaag gacagtgcgt gggccaggga cagtccgccc agcagcacca
     1201 gcagcagacg cgccgacagc gtgcgtggcc agcgtggacg acgtgcggcg gtgttcattc
     1261 gtccggcccc agcaattgca ccggcaggct gaacacatac ccttcgctgc gcacggtctt
     1321 gatgtaggtc ggctcgcgcg cgtcatcacc caggcgctgg cgcacgcggc tgaccagcag
     1381 gtcgatcgag cgatcaaaca gttcggcatc acggccctgg gtgaggctga gcagctggtc
     1441 gcggctgagc acccgattgg cgtgatcgag gaacacgcgc aacaggcgga actcggcgcc
     1501 gctgagcgga tacgcggtgc cctgtgcatc cagcaggtgg cgggcggtgg tatccaggcg
     1561 ccactcgccg aaggccaact ggcggccggc ttcgctcacc tgcaggttcg gcggcagcat
     1621 ctgcgtgcga cggatcaccg cattgatgcg tgccagtagc tcgcgcgaag aaaagggctt
     1681 ggtcacgtag tcgtcggcgc ccatttcaag gccgatgatg cggtcggtct cgtcgtcgcg
     1741 cgcggtcagc agcaccaccg gtaccgcccg atgcttgccg gcgcgcaggt tgcggcacag
     1801 gctcagcccg tcctcgcccg gcatcatcac gtccagcacc accagatcca cggcatgggt
     1861 atccatcagc gcccgcatgg cccggccacc gtcggcctgg ctcacgcgca ggccgttgcg
     1921 ctggaggtag tcggccagca tctggcggat ctcgctgtca tcgtcgacga ccaggatgtg
     1981 cggtacatgg ttcattgcgt tctcgatgaa gacggaggtc agggccgcgc tgcgcggcca
     2041 tggtagcgcg gctcaggggc tggccagcag gcgctggatc tcgctttcgg tacgtgcgta
     2101 gtcgccctcg ccgtaatggc ggtagaccac ccgcccctgc cggtcgagca ggtacagtgc
     2161 gggccagaag cggttgcgcc aggcgttcca gatccggtat tggttgtcct gcaccaccgg
     2221 ccaggtgatg tccaaccgtg cgatggcctt gcgcacgttg ccgggcagcc cttcatgggc
     2281 aaactccggc gtatgcacgc cgatcaccct cagaccctgc ggcgcgtagc gtgcatgcca
     2341 ccggtgaaca tacggcgcca cgttgaggca gttgctgcag gtgtaggtcc agaactcgac
     2401 cagcaccacc tgcccgcgca actgcttcag tgtgagcggt gggctgttgt gccagggccc
     2461 gccaccgtcg aacccggcgg cgggaacggc ctgtgccggc tgcgcgtcgg cctccgggct
     2521 gcgccaggcc atcagtagcg cagccccacc cagcaggctc agcagcaacg gcagcgcaca
     2581 cacacgcagg gcggccatcg ttcagccccc ctgctcggcc agcggcaatt cggccggctt
     2641 cactcccgcc gcttccagga tgctgtcggc cacctgcgcc ggatgcgaaa gcagcgacac
     2701 atggctgctg ccgatcgatt gcagctgtgc accgatgcgc ttggcggtgg cggcctgcag
     2761 ctgcggcgac agcatgcggt catcgcggct gagcacgtac cagctcggct tgctgcgcca
     2821 cgccgcaacg ttcactactt cgcccagcgc gctggccttc aacgggacct gcgtgctgta
     2881 cagcagtgcg gccgacttct tcatcacgtc cggcgcgaag tcctgggcga cggcatcagc
     2941 cggcaacgtc aggtagccat ccctttcctg cagtcgggcc aggcccgggc caaccgggaa
     3001 accctcgccc tgttgcgccg aagactgtcc tgcatccggt gcgaacgcgg ccacgtacac
     3061 cagcgcctgc accttcgggt cattgcccgc ttcggtgatg accgtgccac cccagctgtg
     3121 gccgaccagc accaccttgc caggcgcagc ggcaatcgca cgacgggtgg cggcgacgtc
     3181 gtcggccaac gaggtgagcg gattctgcac agccaccgcc ggcagcttcc agtcatgcag
     3241 ggtgctgatg accttgctcc agctggagcc atcagcgaac gcgccgtgca ccaggatgac
     3301 ggtgggcggt gcaacggtat cggcctgggc agcgaaggca ggggcggcgg cgagggcgag
     3361 agcggcggcc agcaagcagg tacggatcat ggggggcact ccggagttgg gagtggccat
     3421 ttccgcctgc cggtgtatcg gcgctgtttc tccgcagcgc ggagttgtac cggactgtag
     3481 ggcgcaggcg ggtttctaca gtgggataca ttcgcgcgcc ggtcctggcc gggcgctttc
     3541 gggtggatat cgctgcccgc acgcgggcgc gcaacgcccc gatgcgcatc agcgcatcgt
     3601 ctttgtatct gactgtacga aaccccggcc gcggccacag tcgctgacaa aaccccgggc
     3661 aacggcacac gttgccgata cctgcgccgc ctggaatggc ttccatcgac cactggcccg
     3721 caggacacca ccatgatcag caccgcttct tccgtgtata cgccccgcct ggacgccgtc
     3781 ggccgctggc tctcgccgtt ggcgctgcgc accctgctgg cctgggagtt ctttgaatcc
     3841 ggccgcgaga agctgggcgg ccagaactgg ttcgccgact tggaaggccg cttcccgttc
     3901 ccgttctcca cactgcccgc gtcgctgaac tggcagctgg ccacgtggct ggaactggtg
     3961 ggtgcagtga tgctgctgct cggcctggcc acgcgctcgg ttgcctacgt gttctgggta
     4021 ctcaccatcg ttgccatcgc cgccgtgcac tggcccgacc aatggaacgg cctgggtgaa
     4081 ctctggcagg gctatgcgat caccgaccag ggctacggca acttcaagct gccgttgctg
     4141 ttcctggcca tgctgctgcc actgatcctc aacggcggtg gcgcactcag cgtggaccgg
     4201 ctgctggccg gccccggccg tgccacggca ggcaatgacg gcctgggttg gggcgtcagc
     4261 ctgatcgccc tgctgctgcc ggttgccgcg ctgttgcccg gcatcggctt cggcggtgcc
     4321 ctgctcggcg gtgtgctgct gctgggccat ctgctgcgct gtcgccgcgc cgcctgagcc
     4381 gactcccctg ttcccgcgcg tttcgctttc cgtcgcctct tcggcggcgt ccatcccgca
     4441 cgccccgcgt gctttcccaa ggagtcacca ccatgtccat ctcgaccaag aacacctctt
     4501 cctctcgcct gccgcgcatc ggtgccatcg gcatcgccct ggccggtggc ctgctgctgg
     4561 ccggccaggc cgcggcgatc cagccgctgg cgatcagcgc ggtggccatg agcgccgccg
     4621 aaggcaagtg cggtgaaggc aagtgcgggg ccaacaaggc caccaccggc aagcccgccg
     4681 gcaaggccaa ggtggccgag ggccagtgtg gcgaaggcaa gtgcggcgac gcctcgtttg
     4741 cccgcactga tcgcgaccac gacggcaagg tctcgcgtgc cgaattcaac gctgtggccg
     4801 ccaagcgtgc cgccgagttc gaccgcatcg acaccgacca cgacggttac atcagcgagc
     4861 aggaagcgca cgactacctg cgcagcgtct acaccgccaa cggcaagccg atgccgaagg
     4921 gcctgttctc ccgcgttgcc gattgatcga cgttcacccg gcgccgcctt caaggcggcg
     4981 ctctctgtgg agcatccgcc atgtccctgc ccctgcccac ccatgccgcc ggtcttggcc
     5041 tgcgccgtgg cctgatcgac gaactgctgg ccatgccggc cggtgccatc gactttctcg
     5101 aagtctcccc cgacaactgg atcggcgtcg gcggtgcaca cggcgacgcg ctgcgccaac
     5161 tcagcgagcg ccaccccttg acctgccacg gcctgtcgct gtcgctgggc ggtcctgatc
     5221 cgctggaccg caccctgctg gcacagaccc gtgccttcct cgacctgcac caggtgcagc
     5281 tgtacagcga acacctgagc tactgcgccg ccggtggcca tgtctacgac ctgctgccac
     5341 tgccgttcac cgccgaggcc gttcaccatg tcgccggccg tatcgcccag gtgcaggaca
     5401 tgctgggccg acgcatcgcc gtggagaaca tttcctacta cgccgttgcc ggcgcggaca
     5461 tgagcgagat cgacttcatc aacgccgtgc tcgccgaagc cgactgcgac ctcctgctgg
     5521 acgtcaacaa cgtcttcgtc aatgcctgca acaacggtta cgacgccttc gaattcctgg
     5581 ctcgcgtgcc gtcccaccgt gtcgcctcgc tgcacgtagc gggccacttc gatgaagacg
     5641 acggcttcaa gatcgatacc catggggcgc cggtgaaagg cgtggtctgg gcgctcctgc
     5701 gcgaggccta tgcgcggttg ggcgtgcgcc ccacgctgct cgaacgcgac ttcaactttc
     5761 cgccgctggc ggagttgctg gccgaggttg cgcacatccg ccaggcgcag gttgaggcac
     5821 gttggcagga ggtggcccat ggctgagtct ctggccatcg tgcaacggcg ctgggccgat
     5881 catgtacggg acccgtcgat gcctgcgccc gatggcgtcg aggcacggcg gatggcggtc
     5941 taccgccgcc tgtgcatcga cagcctggac acccttttgg caggcagcct gccgcgactg
     6001 ctggaacagc tgggcgaagc gcgctggcgc ggtctggtcg agcgctacta cgcacatcac
     6061 gtctgccata ccccgttgtt cccgcaaatc gccagcgagt tcgctgcgtg gctggctgtg
     6121 cagtatgcgt tcgcgctgcc cggctgggcg gcggaactgg cgcactacga aagcacgcag
     6181 cagacgctgc acatcgtggc acgtgatgcc gggcattcat tgcagtccat gccggcgggc
     6241 agcgatgtgc tggcgctgtc gccgctggtg cgggtattgg gctaccggtg gccggtgcat
     6301 gaggacgccg cgctggacga tgccgccgcc agcgacccga cgcttctgct gctgcgccgc
     6361 ctggcggact accagctgca ggtcgaggaa ctggcaccac tggcgtatgc gctgctgtcg
     6421 gccttcgctg atgacggtac ccacgtggat gacgcgctga acgcactggc cgatgcgcat
     6481 ggcgtggccg ccgacgaact gcgcgtggtg gccacgccct tgctgggcga actatgcgcg
     6541 gccggcgtgc tggtcacgct ggccgggttc tgcgactgcc ggccagcggc cggcactacc
     6601 cctgtctgat tcgaggtttg atcatggctg cttccaacac ttccttcctg cacggctggc
     6661 gccttttcgt gaccatggct gtggtcctga tcgccgtcgc actggcggcg ttcaccctgc
     6721 agcccgacgt ggtcgagggc agccgcgcgg cgatccgggt cactgcacgc acgtcgttcc
     6781 tgctgttcct ggccgcgttc accgcatcgt cgttcgccag cctgctgccc ggcccgttca
     6841 cccagcacat gttgcgcgag cggcgcatca tcggcctgtc attcgcgttc tcgcacctgc
     6901 tgcatgcggt ggcgatcacc gccttcggca tcctcaaccc cgcgttctgg ccggcacgct
     6961 cggccctggc caacctgccg ggcacgatcg gctatgtagc catcctcgcc ctggccatca
     7021 cctcgtatcg tggcatcgcc cgccgcatgg gccccaccgt gtggcgtcgc ctgcacgtga
     7081 ccggcatgtg gatcatcgcc gcagtgttca cctattcgta cttcaagcgc gtgcccggca
     7141 acttctggta cgcggtgccc tccgcgttgc tcttcaccgc tgtcgtggtg cgtgcgatcg
     7201 ccaagcgggc gcagtcgctg cggcgcaatg cgcatgcgcg gccaccgctg cggagttctt
     7261 gaggaggcgg ttacctgtag agccgagccc atgctcggct gcccctggct cagccgagca
     7321 tgggctcggc tctacagagg gatcccagca cgataggcag cgaattccct gcggaaaggg
     7381 atatgcccca cttcaggtca cggggcgcgg cgcagcgtga tcagggtgat ttccgaggac
     7441 accccgatgc gcgcggggaa tccggcccac aggccagcgc cattgctcac gtacagggtc
     7501 atcccatcca cgtcgtagcg gccggagacg aagccaccat tggcccgctt caccaattgg
     7561 tccatgccga tgatctgccc cccgtgggta tgcccggaca actgcagctt cacaccgcgc
     7621 gcagcggcct cacgcgcatt gcgtgggcga tgatcgagca ggatcaccgg cgcggacgga
     7681 tcggcaccct ccagtgcagc ctggagatcc ggcagcggca ggccataacg cgccgccacc
     7741 gggtcggtga caccagcgat ggtcagcgcc gcatcaccgc gtcgcacctg caggtggctg
     7801 ttctccagca cctgcatgtg cagtgcgcgg aacgcctgca tccatgcctg gtactgcgcg
     7861 tagtactcgt ggttgccggt gatggcgatg acaccgtccg gcgcatgcag atcggccaac
     7921 ggacgcgcgt cgtcgcgacg ggcctcgacg ctgccatcga tcagatcgcc ggtgatcacg
     7981 atcaggtccg gcttcagcgc gttgctctcg gccaccactc tacgcaccca gtcgccggtc
     8041 agcagacggc tggcatggat gtcggtcagc tgcagcacgc gatagccgtc gaacgccgct
     8101 ggcagcccgg caatgctcac ctcgatctgc cgggcatgag gcaccgccat gccctggctg
     8161 acaccataac cactgaccag cagcgccagc acgccggccg ccggccgcaa gcgccgcgtg
     8221 cgcaatgcgg ctaccgcacg tggccagagc agcaggcggg acgcgagcag gcccgcatcc
     8281 atcgccagca tcagcaacgc caacagcaac accgccgtgg agccggtagc cagcgtggcg
     8341 atggccagtt tcggaatctc gggcgaggcc atcgtgcccc agaacgtggc gacgatacgc
     8401 agctgcacgg ctacgcccac cagcagcagc gacagcacga ccttctgcca ggggggcatg
     8461 cgcagtggcc agaacaggcg ccaggccaca tacaggccca tcaacaaacc gatcgtactc
     8521 agcactgcaa ccatccggga gggaaagtgg gggccgccat ggtgacggct gcgggcggcg
     8581 ttgtgtagcg ccgagcccat gctcggcttc tcaacatgca gccgagcatg ggctcggctc
     8641 tacatcaaca ggtgggtcag gccattccgt cgaggcgctg cacccgcagg cgggcgatgc
     8701 ggcgcttctc catcgccagc acggtgatgc gcacacccgc cacctccacc acatcgccga
     8761 tgtccggcag ccgacccaac tgctccagca ccagcccgga gatggtcatg tagtcggcac
     8821 tgcgcggcag cgatacgccg gccagccgct gcaggtcgtc cagagtcagc gcaccgtcgg
     8881 cctcccattg gtcctcgccc tgcgcgacca cgccatagcg ctcgtcctgg gtatcgacca
     8941 ggtcaccggc aatggccgcc agcaggtcgt tggcggtcac caggccttcc acgctgccgt
     9001 actcgtccac cgccaccgcc agcggcaccg ggtgctggcg gatcagttcc agcgcctgca
     9061 gcgcgctggc actggacagc acgtactgcg gctcgcgcag gttgccctcc aactgcagcg
     9121 gcctgccctg cagcaggtcg gccagcaggt cgcggctctg caccacgcca cgcaggctgt
     9181 ccaggtcacc ctcacccacc agcaggcggg tgtgcggcga cgccaccaag cgtgccacca
     9241 catcctcctg cccacgcgcc aagtcgatcc actgcacgtc ggcacgcacc gtcatcacgc
     9301 tcgacaccgg gcgatcggcc aggcccagca cgctgcggat catctcgtgt tcggccggct
     9361 gcaagcgctc tgcagtgtcc acctgcccgt cccccccttc atcgtcgtga ccattggccg
     9421 ggcgcgcgcc cagcatgcgc agcacggcat cggcggtgcg ctggcggaac ggcaggcggc
     9481 gctcgttgcg ctcgcggttg aaacgcaccc actggttgaa cgcctcgacc aggatcgaga
     9541 aggcgatcgc cgcgtacagg tagcccttgg ggatcttgta gcccagtcct tcggccacca
     9601 ggctgaagcc gatcatcagc aggaagccca ggcacagcac caccacggtg ggatgtttgt
     9661 tgacgaagcg ggtcagcggc ttgctggcca gcagcatcag cgccatggcg atcgtcacgg
     9721 ccgcatacat cacgcccagg ttgtcgacca tgccgaccgc ggtgatcacc gagtccagcg
     9781 agaacaccgc gtcgagcacc acgatctgcg ccaccaccat tgcgaagctg gcgtagacct
     9841 tcttgccgtc ctcgtggtgt tcgcggcctt ccagccgttc gtgcagttcc atggtgccct
     9901 tgaacagcag gaacagacca ccgccaagca ggatcaggtc tcgcccggaa aagctgtggt
     9961 cgaacagcgt cagcagcggc gcggtcagtt tcatgatcca ggccagtgcg gccaacagca
    10021 ccagccgcat cagcaaggcc agcgccaggc cgatcacccg cgcgcggtca cgctggtgcg
    10081 gcggcagctt gtcggcaagg atcgcgatga acaccaggtt gtcgatgccg agaacgatct
    10141 ccagcacgac cagggttgca aggcccatcc agatcgaggg gtcagccaac cattccattt
    10201 caggtccgtt tcgtcagtag ataagggaaa agagcgaccg ctcagtcagc gtcatgtgcc
    10261 tgcgccgggt cgtgcccgag caggtcaccg ggcgtgcact gcagctcgcg gcagatcgca
    10321 tcaagggtgg aaaagcggat ggcgcgcgcc ttgccggtct tcaggatcga caggttggcc
    10381 agggtgatgt cgatgcgccc ggccagctcg gacagggtca tgcccctttc ctgcagcatg
    10441 cggtccaggg taatgacgat tgccatcaga tgacaccgtc gaggtcatcg cgcatcgctg
    10501 cgcccacggc gaagacgcgc gccagcacga acagcatcag cacggccacc aagccagtga
    10561 tcgacatgcc accgccgacc tccatccagg tgaaatccgg gcccatccag gccgcgtagg
    10621 cgccgatcag gatcgacagc agctccatcg ccagcatcag ccaggccatg cgctgcaggc
    10681 gctgtgcgtt ggcgtgggtg aacggccgct cgcgcgccgc cgacttcagc agccgcagca
    10741 ggtggcgcag gaacatcagg cacagcacca gcagcgcgac gatcgcgccc aggcccaggc
    10801 agaaatgcag gaacaggtca ttgccatgcg cggcgacagc cgcagc
//
