LOCUS       NZ_KB907498            10876 bp    DNA     linear   CON 21-MAY-2024
DEFINITION  [Pseudomonas] hibiscicola ATCC 19867 G370DRAFT_scaffold00001.1,
            whole genome shotgun sequence.
ACCESSION   NZ_KB907498
VERSION     NZ_KB907498.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      [Pseudomonas] hibiscicola ATCC 19867
  ORGANISM  [Pseudomonas] hibiscicola ATCC 19867
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 985584)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name :: Stenotrophomonas maltophilia ATCC 19867
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: ATCC 19867
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. R37654
            finishing_strategy                :: Missing
            environment                       :: Host
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi15375
            Type Strain                       :: No
            Funding Program                   :: DOE-CSP 2012
            Isolation Site                    :: Plant
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. R37654
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000382065.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 01:07:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,084
            CDSs (total)                      :: 4,007
            Genes (coding)                    :: 3,964
            CDSs (with protein)               :: 3,964
            Genes (RNA)                       :: 77
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 15 of 43
            Pseudo Genes (incomplete)         :: 31 of 43
            Pseudo Genes (internal stop)      :: 7 of 43
            Pseudo Genes (multiple problems)  :: 7 of 43
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:56:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 357534
            Orig. end                         :: 368410
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB907498.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 408460
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Nikos  Kyrpides (nckyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-PGF and JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10876
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10876
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10876
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5876](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5876
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(212..226)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
     misc_feature    463..476
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            944..1912
                     /db_xref="GeneID:90524170"
                     /gene="pstC"
                     /locus_tag="G370_RS0101885"
     CDS             944..1912
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90524170"
                     /gene="pstC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008572163.1"
                     /locus_tag="G370_RS0101885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="WP_019659079.1"
                     /transl_table=11
                     /translation="MNAIAQPVAAPSTRDARDARNDTLFRWVLVGTVIFVLIALACAAL
                     SMLWGGRHALQMQGLSFFFSADWNPVENKFGALAPIYGTLVTAVIAMVIAVPVSFGIAF
                     FLTEVAPRWLRGPVGTAIELLAGIPSIIYGMWGLFVLVPVMTEYVTPFLNETLGEWPVI
                     GPMFQGPPLGIGMLTAGFVLAIMVIPFISSVMREVFLTVPTRLKESAYALGSTKWEVSW
                     DIVLPYTRSAVIGGIFLGLGRALGETMAVAFVIGNSVRLSPSLLEPGTTIAALIANDFG
                     EATETYRSALLLLGFVLFIVTFVVLAIARLMLMRLSRKEGN"
     gene            1912..2775
                     /db_xref="GeneID:90524171"
                     /gene="pstA"
                     /locus_tag="G370_RS0101890"
     CDS             1912..2775
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90524171"
                     /gene="pstA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412770.1"
                     /locus_tag="G370_RS0101890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="WP_005415894.1"
                     /transl_table=11
                     /translation="MSTTADSLYLRRRIGNVVAITASCATALFGLFFLGWILFTLAAKG
                     LAGINWDLFTKMTPPPMQDGGLANAFFGSAVMCALAIGIGTPLGVLAGTWLAEYGNARK
                     AGTVVRFVNDILLSAPSIVLGLFVYTLYVMQTGGNFSAFAGALSLAFIVLPVVVRTTDE
                     MLRLVPSQMREAALSLGIPQWKVIVQVLYRSASAGIITGILLALARISGETAPLLFTAF
                     GNQYWNNNIFQPMASVPVVMNQFAGSPYESWQVLAWAGALVLTVFVLLVSLAARGILLR
                     NRISHD"
     gene            2795..3625
                     /db_xref="GeneID:90524172"
                     /gene="pstB"
                     /locus_tag="G370_RS0101895"
     CDS             2795..3625
                     /EC_number="7.3.2.1"
                     /GO_component="GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90524172"
                     /gene="pstB"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019237787.1"
                     /locus_tag="G370_RS0101895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="WP_005408788.1"
                     /transl_table=11
                     /translation="MNDLSNAVPMQRIAVPSSHESLHTPSPVKLAARGLDFYYDKFHAL
                     KGINLEIPEKRVTALIGPSGCGKSTLLRIFNRIYALYPKLEARGEVLLDGENILSPKYP
                     MNRLRSKVGMVFQKPVPFPMTIFENVAYGIRHHEKLSKADMADRVEQALRQGALWDEVK
                     DKLGQSALGLSGGQQQRLCIARAVALRPSVLLLDEPTSALDPISTSRIEQLVEELKHEY
                     TIVIVTHNMQQAARVSDYTAFMYLGDLIEHDRTEVIFSQPSQRQTEDYITGRFG"
     gene            3691..4398
                     /db_xref="GeneID:90524173"
                     /gene="phoU"
                     /locus_tag="G370_RS0101900"
     CDS             3691..4398
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0051049 - regulation of transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90524173"
                     /gene="phoU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265615.1"
                     /locus_tag="G370_RS0101900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="WP_005408787.1"
                     /transl_table=11
                     /translation="MNLPNDHIVKSYDEEQQRLVAEIVRMGEMAVAQLEASMDVIEKRD
                     ENAAHRIIANDEAIDALEQQISHDVMRLALRGPMARDLREILAGLRIPADIERIGDYAA
                     NVAKRSIALGKVPPLPQIQGLRALGRLAAQQVRRAIAAYRDNDADAALELREDDARLDA
                     QYTALFRELLTYMMEDPRNITPCTHLLFMAKNLERVGDHATNIAENVWFLVHGEQPLPP
                     REKRDETSSTGQP"
     misc_feature    complement(3704..3719)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.64"
                     /tool="antismash"
     misc_feature    4529..4544
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     gene            4658..5014
                     /db_xref="GeneID:90524174"
                     /locus_tag="G370_RS0101905"
     CDS             4658..5014
                     /codon_start=1
                     /db_xref="GeneID:90524174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659080.1"
                     /locus_tag="G370_RS0101905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_019659080.1"
                     /transl_table=11
                     /translation="MSSSNKTLSLLTATALAAGLGITANASALSMSDLAQGYLVAGQAA
                     KASTDAKGADAKTSAEAAKHAEGKCGADGKSAEGKCGADKGKAAGAAAGAKAQAGDKKA
                     AEGKCGEGKCGGKH"
     gene            5001..5876
                     /db_xref="GeneID:90524175"
                     /locus_tag="G370_RS0101910"
     CDS             5001..5876
                     /codon_start=1
                     /db_xref="GeneID:90524175"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014036545.1"
                     /locus_tag="G370_RS0101910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_019659081.1"
                     /sec_met_domain="DUF692 (E-value: 6.5e-116, bitscore:
                     382.1, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASTEVRASIANLRSPLRAAAVGLGLRRALLQELRDAPAGDFDFL
                     ECAPENWIHVGGPAGDALAELAQRHPLSCHGLSLSLGGTAPLDTQLLEQVGQFLEKHRV
                     PLYSEHLSYCSDDGHLYDLLPIPFTDEAVRHTAARIARVQNVLGRRIAVENVSYYLAPE
                     PAMDELAFTNAVLAEADCDLLLDVNNVYVNACNHGYDADAFIAGLPADRIVCLHVAGHL
                     DEAPDLKIDTHGSAVIDPVWELLARTYARIGARPTLLERDFNFPPYAELRGELQTIRRL
                     QAVHAEAAYG"
     gene            5869..6624
                     /db_xref="GeneID:90524176"
                     /locus_tag="G370_RS0101915"
     CDS             5869..6624
                     /codon_start=1
                     /db_xref="GeneID:90524176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017356811.1"
                     /locus_tag="G370_RS0101915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_019659082.1"
                     /transl_table=11
                     /translation="MADTPATLRAQQHAFTAYLRDPQGVPPPGGLEPRRVAVYQRLLFN
                     NLLGLLSNGFPVCVRLLGVSAWSGLVRHYFATHRCQTPLFTELAAEFVQWLQAQPQLPH
                     PALAELAHYEWVETALYQLDAEPLPVVADIDPLRVPLQRSPLAWPLLYQWPVHRLGAED
                     APTQLPAEPTGLLVRREADGEVRFAVLSPLAVYLLSSIGEQPGLDGHAYLKQLADAHGL
                     AEQALAEPGAALLQQFLRAGVIGPLTAPA"
     gene            6656..7177
                     /db_xref="GeneID:90524177"
                     /locus_tag="G370_RS0101920"
     CDS             6656..7177
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90524177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014036543.1"
                     /locus_tag="G370_RS0101920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DoxX family protein"
                     /protein_id="WP_019659083.1"
                     /transl_table=11
                     /translation="MKLPPLATARGQLDRLAPWLAPLGLRLLLAWEYFESGREKLQGQN
                     WFADLQDAFPFPFNQLPAALNWQLATWFELLGAACLLFGFGTRFAAASLLVLTVVATYA
                     VHWPMQWNSLGDLAMGYAISDQGYGNFKLPVLFMAMLLPLVFTGAGRLSVDALLWRWHP
                     SGTTARPAVR"
     gene            7297..7947
                     /db_xref="GeneID:90524178"
                     /gene="rnt"
                     /locus_tag="G370_RS0101925"
     CDS             7297..7947
                     /GO_function="GO:0016896 - RNA exonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA]"
                     /GO_process="GO:0006364 - rRNA processing [Evidence IEA]"
                     /GO_process="GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90524178"
                     /gene="rnt"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479630.1"
                     /locus_tag="G370_RS0101925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonuclease T"
                     /protein_id="WP_019659084.1"
                     /transl_table=11
                     /translation="MTDPIPAPAAAPDSAVSQAQRAMSQRFRGFLPVVVDVETGGFDSQ
                     RNALLEIAAVPIEMDENGLLYPGQTASAHVVPAEGLEIDPKSLEVTGIILDHPFRLAKE
                     EKAALDHIFTPVRAAMKKYGCQRAILVGHNAHFDLGFVNAAVARTGHKRNPFHPFSVFD
                     TVTLAGIAYGQTVLARAATAAGLGWDANEAHSAVYDTEQTARLFCTIANAWPR"
     misc_feature    complement(8361..8381)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.71"
                     /tool="antismash"
     misc_feature    complement(9361..9375)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.64"
                     /tool="antismash"
     misc_feature    9831..9846
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     misc_feature    10484..10498
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.37"
                     /tool="antismash"
ORIGIN
        1 aagatcaact accagtcgat cggctccggc ggcggcatcg cccagatcaa ggccggcacc
       61 gtcgactttg gttcgtccga caagccgctg agcagcgagg agctggccca ggccggcctg
      121 gcgcagttcc cgtcggccat cggcggcgtg gtgccggtgg tcaacatcga aggcctggaa
      181 gccggcaagc tgcgcctgag cggcgccctg ctggccgaca tcttcctggg caaggtcaag
      241 acctggaacg acccggccat cgtcgccgcc aacccgggcg tgaagctgcc agacggcaag
      301 atcaccctgg tccaccgttc ggacggttcg ggcaccacct tcaacttctc caactacctg
      361 tccaaggtca gcccggagtg gaagagcaag gtcggcgaag gcacctcggt gcagtggccg
      421 gacggcgtcg gtggcaaggg caatgaaggc gtcgcgtcct acgtgaagca gatcaagggc
      481 tcgatcggtt acgtcgaact ggcctacgcg ctgcagaacg gcatgccgta caccgccatg
      541 cagaacgcgg ccggcaactg ggtcgagccg agcgcggaga ccttcgccgc cgcggccgcc
      601 agcgccgact gggccagcgc caaggacttc aacctggtca tcaccaatgc cccgggcgag
      661 caggcgtggc cgatcaccgc caccaacttc atgctgatgc agaagaagcc gaaggatgcc
      721 aagcgcaacc aggacaccct ggccttcttc aagtgggcct tcgaaaacgg ccaggcgcag
      781 gccaacgagc tgcactacgt gccgctgccg gccgaactgg tcaagcagat cgaggcctac
      841 tgggcgaccg acctgaagtg atggacacga cggtgcccgc cccgcgcggg caccgcttgt
      901 tccgcgccgt gccgccccgc cccttcctgg cccagccgtc cccatgaatg ccatcgccca
      961 gcctgtagcc gccccgtcca cgcgtgatgc gcgtgatgcc cgcaacgaca cactgttccg
     1021 atgggtgctg gtcggcaccg tcatcttcgt cctgatcgcc ctggcctgcg ccgcgctgtc
     1081 gatgctgtgg ggcggtcgcc atgccctgca gatgcagggc ctgagcttct tcttctccgc
     1141 tgactggaat ccggtcgaaa acaagttcgg cgctctggct ccgatctacg gcaccctggt
     1201 caccgccgtc atcgcgatgg tcatcgccgt gccggtcagc ttcggcatcg ccttcttcct
     1261 caccgaagtc gcgccgcgct ggctgcgtgg cccggtcggt accgccatcg aactgctggc
     1321 cggcatccct tcgatcatct acggcatgtg gggcctgttc gtgctggtgc cggtgatgac
     1381 cgagtacgtc accccgttcc tcaacgagac cctgggcgaa tggccggtga tcggcccgat
     1441 gttccagggc ccgccgctgg gcatcggcat gctcaccgcc ggtttcgtgc tggccatcat
     1501 ggtcattccg ttcatctcct cggtgatgcg cgaagtgttc ctgaccgtgc cgacccgcct
     1561 gaaggaatcg gcctatgcgc tgggctccac caagtgggaa gtgagctggg acatcgtcct
     1621 gccctacacc cgttcggcgg tcatcggcgg catcttcctc ggcctcggcc gcgcgctggg
     1681 cgaaacgatg gcggtggcct tcgtgatcgg caacagcgtg cgcctgtcgc cgtcgctgct
     1741 ggaaccgggc accaccatcg ccgcgctgat cgccaatgat ttcggcgaag ccactgaaac
     1801 ctaccgttcg gccctgctgc tgctcggctt cgtcctcttc atcgtcacct tcgtggtgct
     1861 tgccatcgcc cgcctgatgc tgatgcgcct gtcccgcaag gagggcaact gatgtccacc
     1921 accgctgatt cgctgtacct gcgccgccgc atcggcaacg tcgttgcgat cactgcgtcc
     1981 tgcgccaccg ccctgttcgg cctgtttttc ctgggctgga tcctgttcac cctggctgcc
     2041 aagggcctgg ccggcatcaa ctgggatctg ttcaccaaga tgacgccacc gccgatgcag
     2101 gacggcggcc tcgccaacgc cttcttcggc agtgccgtga tgtgtgcact ggccatcggc
     2161 atcggcaccc cgctgggcgt gctggccggc acctggctgg ccgagtatgg caacgcccgc
     2221 aaggccggca ccgtggtccg cttcgtcaac gacatcctgc tgtcggcgcc gtccatcgtg
     2281 ctgggcctgt tcgtctacac gctgtatgta atgcagaccg gcggcaattt ctcggcgttc
     2341 gccggcgccc tgtcgctggc cttcatcgtg ctgccggtgg tggtgcgcac caccgacgag
     2401 atgctgcgcc tggtgccctc gcagatgcgc gaagcggccc tgtcgctggg catcccgcag
     2461 tggaaggtga tcgtgcaggt gctgtaccgc agtgcctcgg ccggcatcat caccggcatc
     2521 ctgctggcgc tggcccgcat ctccggcgag accgctccgc tgctgttcac cgccttcggc
     2581 aaccagtact ggaacaacaa catcttccag ccgatggctt cggtgccggt ggtgatgaac
     2641 cagttcgccg gcagcccgta cgaatcctgg caggtactgg cctgggccgg tgccctggtg
     2701 ctgactgtct tcgtgctgct ggtcagcctt gccgcccgcg gcatcctgct gcgcaaccgt
     2761 atctcccatg actgaccttt ccgtggacaa cgccatgaac gacctttcca acgccgtgcc
     2821 gatgcagcgc atcgccgtgc cgtcctcgca cgagagcctg cacacgccgt cgccggtgaa
     2881 gctggctgcg cgtggactgg acttctacta cgacaagttc cacgccctga agggcatcaa
     2941 cctggaaatt ccggaaaagc gcgtgaccgc gctgatcggt ccttccggtt gcggcaaatc
     3001 gaccctgctg cgcatcttca accgcatcta cgcgctgtac ccgaagctgg aagcgcgcgg
     3061 tgaagtgctg ctggacggcg agaacatcct gtcgccgaag tacccgatga accgcctgcg
     3121 cagcaaggtc ggcatggtgt tccagaagcc ggtgccgttc ccgatgacca tcttcgagaa
     3181 cgtggcctac ggcatccgcc accacgagaa gctgagcaag gccgatatgg ccgaccgcgt
     3241 cgagcaggca ctgcgccagg gtgcactgtg ggacgaagtg aaggacaagc tggggcagag
     3301 cgcgctgggc ctttccggtg gccagcagca gcgcctgtgc atcgcccgtg ccgtggcgct
     3361 gcgcccgtcg gtgctactgc tggacgagcc gacctcggcg ctggatccga tctcgaccag
     3421 ccgcatcgag cagctggtgg aagagctcaa gcacgagtac accatcgtca tcgtcaccca
     3481 caacatgcag caggccgcgc gcgtttccga ctacaccgcc ttcatgtacc tgggcgacct
     3541 gatcgagcac gaccgcaccg aagtgatctt ctcgcagccg tcgcagcggc agaccgagga
     3601 ctacatcacc ggtcgcttcg gctgatcgac gctgatcctt cgccacatgt cccagccagg
     3661 cacggcttgg ctccacccgg attgcagacc atgaaccttc ccaacgacca catcgtcaag
     3721 agctacgacg aagagcagca gcgcctggtg gccgaaatcg tgcgcatggg cgagatggcc
     3781 gtcgcccagc tcgaagcgtc gatggacgtg atcgagaagc gcgacgagaa cgccgcccat
     3841 cgcatcatcg ccaacgacga agccattgat gcgctggagc agcagatcag ccatgacgtg
     3901 atgcgcctgg ccctgcgtgg cccgatggcg cgcgacctgc gcgaaatcct cgctggcctg
     3961 cgcatcccgg ccgacatcga acgcatcggc gactatgcag cgaacgtggc caagcgttcg
     4021 atcgcgctgg gcaaggtgcc gccgctgccg cagatccagg gcctgcgtgc gctgggccgc
     4081 ctggcggcgc agcaggtccg tcgtgccatt gccgcctacc gcgacaacga cgccgacgcc
     4141 gcactggaac tgcgcgagga cgacgcccgc ctggacgcgc agtacaccgc gctgttccgc
     4201 gagctgctga cctacatgat ggaagacccg cgcaacatca ccccgtgcac gcacctgctg
     4261 ttcatggcca agaacctgga gcgcgtgggc gaccacgcca ccaacatcgc cgagaacgta
     4321 tggttcctgg tgcacgggga gcagccgctg ccgccgcgcg agaagcgcga cgagacctcc
     4381 agcaccggcc agccctgacg ctgcactgca acaccggagt cgactccaag gtggccgctg
     4441 tcctggtgac agcggccttc ttgtttctgg gcgttccggc gattcatcca cgcatggcgt
     4501 ggatccaccg ggaaccgtgt tccccttctg taacaaacct cacgaaaatt tgaggtcttg
     4561 gcgaggattc gttgagtagg atcgctgcac catcgtttcc accggcatcc ctgccggcca
     4621 cccgggcacc cgcccacacc acccaggagc acgaccgatg agcagttcca acaagaccct
     4681 gtccctgctg actgctaccg ccctggccgc cggccttggc atcaccgcca atgcctcggc
     4741 gctgagcatg agcgacctgg cccagggcta tctggtggct ggccaggctg ccaaggccag
     4801 caccgatgcc aagggcgccg acgccaagac ctccgcagag gccgccaagc atgccgaagg
     4861 caagtgtggc gcagatggca agtccgccga aggcaagtgc ggcgccgaca agggcaaggc
     4921 tgccggtgcg gcagcaggcg ccaaggctca ggccggcgac aagaaggccg ccgaaggcaa
     4981 gtgtggcgaa ggcaagtgcg gtggcaagca ctgaggtccg cgccagcatc gccaacctgc
     5041 ggtcgccgct tcgtgcggcg gccgtcgggt tggggctgcg ccgggcgctg ttgcaggagc
     5101 tgcgcgatgc accggctggc gatttcgatt tcctcgaatg cgcgccggag aactggatcc
     5161 atgtcggcgg ccccgccggt gacgcactgg ccgagctggc acagcgccat ccgctgagct
     5221 gccacggcct gtccctgtcg ctgggcggca ctgcgccact ggatacgcag ctgttggagc
     5281 aggttggcca gttcctggaa aaacaccgcg tgccgctgta cagcgaacac ctgagctact
     5341 gcagcgacga cggccacctg tacgacctgc tgccgatccc cttcaccgat gaagcggtgc
     5401 gccataccgc cgcacgcatc gcccgcgtgc agaacgtgct gggtcgccgc atcgcggtgg
     5461 aaaacgtgtc ctactacctg gcaccggaac cggcgatgga cgaactggcc ttcaccaacg
     5521 ccgtgcttgc cgaagccgac tgcgacctgc tgctggacgt caacaacgtc tacgtcaacg
     5581 cctgcaacca tggttacgac gccgacgcgt tcatcgctgg cctgcccgca gaccgcatcg
     5641 tctgcctgca cgtggccggg catctggacg aggcaccgga cctgaagatc gatacccatg
     5701 gcagcgcggt gatcgacccg gtctgggagc tgctggcacg cacctatgcg cgcatcggcg
     5761 ctcgccccac cctgctcgaa cgcgatttca atttcccgcc ctatgccgaa ctgcgcggcg
     5821 aactgcagac catccgccgt ctgcaggccg tgcacgcgga ggcggcatat ggctgatacc
     5881 cccgccacgc tgcgtgcgca gcagcacgca ttcaccgcct atctgcgaga tccccagggc
     5941 gtgccgccac cgggcgggct ggagccacgg cgcgtcgcgg tctaccagcg gctgctgttc
     6001 aacaacctgc tcggcctgtt gagcaacggc tttccggtct gcgtgcgcct gctcggcgta
     6061 tcagcctgga gcggactggt gcgccactac ttcgcaaccc atcgctgcca gacgccgctg
     6121 ttcaccgaac tggccgccga attcgtgcag tggctgcagg cacagccgca gctgccacac
     6181 cctgcgctgg ccgaactggc ccactacgag tgggtggaaa ccgcgctgta ccaactggac
     6241 gccgaaccgc tgccggtcgt agcggacatc gacccgctgc gggtgccgct gcagcgctca
     6301 ccgctggcgt ggccgctgct gtaccaatgg ccggtgcacc gcctcggcgc cgaggacgca
     6361 cctacccagt tgccggccga gccgaccggc ctgctggtgc gtcgcgaggc cgatggcgag
     6421 gtgcgcttcg ccgtactcag cccgctggcg gtgtacctgc tgtccagcat cggggagcag
     6481 cccggcctcg atggacatgc ctatctgaag caactggccg acgcgcatgg cctggccgaa
     6541 caagcgctgg ccgaacccgg tgccgcgctg ctgcagcagt tcctgcgggc cggcgtgatc
     6601 ggccctttga ccgcacctgc ctgacacctc ccttccccga cccggagatg caccgatgaa
     6661 gcttccgccc ctggccaccg cgcgtggcca gctggaccgt ctcgccccct ggttggcccc
     6721 gctcggcctg cggctgctgc tggcctggga atacttcgaa tccggccgcg agaaactgca
     6781 aggccagaac tggttcgccg atctgcagga cgccttcccg tttccgttca accagctgcc
     6841 cgctgccctg aactggcaac tggccacctg gtttgaactg ctcggcgcag cctgcctgct
     6901 gttcggtttt ggtacccgtt ttgccgctgc cagcctgctg gtgctgaccg tggtggccac
     6961 ctacgccgtg cactggccga tgcaatggaa ctcgctgggc gacctcgcga tggggtatgc
     7021 gatcagcgac cagggctacg gcaacttcaa gctgccggtg ctgttcatgg cgatgctgct
     7081 gccgctggtc ttcaccggcg caggcaggct gagcgtggat gcgttgctgt ggcggtggca
     7141 tccgtcgggt acgacggcac gtcccgcagt ccggtagatc cgaccttggt cggcgcatcg
     7201 cgtgccaacc aaggctggca cctaccgggt tctgccacgg tggcgggcat gggctgcgtg
     7261 gccgggcgct cagggtcgct ctgctagaat tcacgcatga ccgaccccat tcccgcacct
     7321 gccgccgctc ccgattccgc agtatcccag gcgcagcgcg cgatgtcaca acgcttccgc
     7381 ggtttcctgc cggtggtggt ggatgtggaa accggcggct tcgacagcca gcgcaacgcg
     7441 ctgctggaaa tagccgcagt gccgatcgag atggacgaga acggcctgct gtacccgggc
     7501 cagaccgcca gcgcccatgt agtgccggcc gaaggcctgg agatcgaccc gaagtcgctg
     7561 gaagtgaccg gcatcatcct cgaccatccg ttccggctgg ccaaggaaga aaaggccgca
     7621 ctggaccaca tcttcacccc ggtgcgcgca gcaatgaaga aatacggctg ccagcgcgcg
     7681 atcctggtcg gccacaacgc ccatttcgac cttggcttcg tcaacgccgc cgtggcccgc
     7741 accggtcaca agcgcaaccc gttccatccg ttcagcgtgt tcgacacggt caccctggcc
     7801 ggcatcgcct acgggcagac cgtgctggcg cgcgccgcca cggccgccgg gctgggctgg
     7861 gatgccaacg aggcacacag cgcggtgtat gacaccgaac agaccgcgcg gctgttctgc
     7921 accatcgcca acgcctggcc gcggtaaggc agccaacggc gcaaccgcat ccacgcagtg
     7981 cggaccaacg gtccgcaccc accactcacc gcacggtaga tccacgccac gcctggatga
     8041 gatcaaccaa tactcgtacg atcgcggcca tcgctcttgg cgcggtacag tgcgcggtct
     8101 gcgcgctggt acagcagcgc cggggtgcgg tcgtcggcat ccagctccac caggcccgcg
     8161 ctgaaggtca cgcgcaggcc ttccacaccg gcccagtccg ggtggtcatg gaacagaccg
     8221 cgcaggcgtg cgcacagctg tgcggcctct tccaggcggg tgtcgttgag cagcagcgcg
     8281 aactcttcac cgccggtgcg cgccggcagg tccgaatcgc ggcaggccgc agcgatcaag
     8341 cgcgccacct gcaccagcac ggcatcgccg atgctgtggc tgtggcggtc gttgacgtcc
     8401 ttgaagtggt cgatatccag caccaccagg cacagtggat gaccactgcg ctgcgaacgg
     8461 gcgaagtcgc gggcaagggt ttcgtcgaag gcgcggcgat tgggcaggcc ggtcagtgca
     8521 tcctcgcggg cctgccgttc aaatgcctca gcctggcgtg ccaggcgctc ggccagttcg
     8581 gtcttttcct ggttcaacgc ctgcaggtgc acggtcttgg cctgcaggtc gaaagttgct
     8641 tcgtccaccc gacgtgccag gcgcaggttg ctggccttca actgctgcag cagcaagcgg
     8701 tacagcgcca ccagcccggt cagcagcacc agtgccccca gcacctgcac gctgcgtcgc
     8761 tgccaccaga acggctccac ggtgaagctc cacaccgcct cctgctggcc ccagctgcca
     8821 ccgggatgtg ccgccgccac gtgcagggtg tattcgcccg gcggcaggcc gacgaactcc
     8881 acgctgcgct gcgggccgcg ctcgacccag ccggcatcaa gcccatccaa ccgcgtgcgg
     8941 taacggatcc ggtcagacat caggtagctc aggccgacat agctgaccgc caggcggcgg
     9001 ccaccgggaa tggcgttgcg atccggtcct tcccaatgca ccggcgcgcc atccacctgc
     9061 acgctctcga tcgcggcggg cggcgatggc cgctcgcgga agcgctgcag gcgctgcgga
     9121 tcaaccgtgc tcaggccacc ggcagtcacc acccagaacg tgccgtcctg gcgcaggatc
     9181 gccgaaggcc ccgagctgcc gttggcctgc gcattggcca tgccgtcgat ctcgttgtag
     9241 cgctccacca tcacccgggg tgctcggcca tcggccaccg cgttcagggt agccatgtcg
     9301 gtgcgcagca cgcctcggtt gctgctgacc cacacgttgc caagacgatc aggcaccagc
     9361 tggaacaccg cgtccaccgg cataccctgc tcgagcccca cccgcgccag catcccgttc
     9421 cgccagcggt acaggccacg gtcgctgctg atccacatcg cgtcgcccag ctggtggaag
     9481 ccgaacacgc tgcggccacc gcccatcggc gcgaggtcga tcgactgcac gtggtcgccg
     9541 cgcagcacgc ggattccctc gatggtgccg atccacaggt tgccctgatg atcgtgctca
     9601 agcgcggtga tcaggccgcc gggcatgccc gccatgcttg atacctgcac acggtcgccg
     9661 tcgatgcgga ccacgccctt ctgcgtgccg gcccagacca cgccctgcgg gtctacgctg
     9721 atcgcgcgga tgttgccgcc cggcatgcca tcggcagcgg cgtagttgtg ccgcagccgg
     9781 ccgtcgcgac caagacggta gacgccatcg ccgaacgtgc cgacccacag gtcaccgtcc
     9841 ggtccctgcg ccaggctgag caccgaaggt gccttgccac cgcggttgtg cagaggcatc
     9901 gcacggaagc ggccgtcggc cgtctgcaga tcgaggccgc tggcgctgcc cacccagagc
     9961 tggcggtcgc ggtcctcgaa cacggtgcgc acatagtcgc cactgagccc atcgcgctcg
    10021 gtgtaactgc tgaacagcgt ttcgcgcagg cggtacagcc cgccgttggc gcccacccag
    10081 atgctgccct cggcgtcctc gcgcaggctg accacgcgtc cgcccggcag gttcaggcct
    10141 gccggcagcc gctccaggcc atgtgcggag atgcgcagca ggccctggtt ctcggtgccc
    10201 agccacaggt caccatggcg atcctgcagc atcgaggtca tgtgcagctg tcccggcaga
    10261 cggtgcatca gcaccagctg gtcatcttcc acccggtaca ggcgctcgcc ggcgacgatc
    10321 cacagcgcac catccggcgc acggtagggc catgaaagac cactgccggc ccccagtccc
    10381 caggctgcgg gcgcgcgttt gagcacgccg tcgttgtcgc gcagcaccag cccgtccagc
    10441 gtaccgaccc agacccggtc ctgcgcatcg accaccagct tggtgaaact catcgccatc
    10501 ggaaggtccg ccgccggcgc ctggtagacg atgccattgt ccggtgtcag atagccgatg
    10561 cccttgccct cgtacagcag ccacagccgg ccctggctgt ccatctgcat ggactgtatc
    10621 agcacctgcg gcgtatcggc ctggtgctcc cagacgcgcc actggccatc gctgccacgg
    10681 tggctgacgt tgccgcgcga atcactgatc cacaagccac cctggcggtc gacgaacagc
    10741 gcaccgatgc cgttgtcgcg caggcccggg cgggtgctgc ggtcgaacac ggtgaaatcc
    10801 aggccgttgt agcgcaccag gccttcccag gtcgcgaacc acaggtggcc ttcgggggtc
    10861 tgcgcgatgt cacgca
//
