LOCUS       NZ_KB905813            18535 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Streptomyces sulphureus DSM 40104 F603DRAFT_scaffold00001.1, whole
            genome shotgun sequence.
ACCESSION   NZ_KB905813
VERSION     NZ_KB905813.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sulphureus DSM 40104
  ORGANISM  Streptomyces sulphureus DSM 40104
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 939081)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name :: Streptomyces sulphureus DSM 40104
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: DSM 40104, ATCC 27468
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. R37654
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi11971
            Current Finishing Status          :: Level 1: Standard Draft
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2012
            Sporulation                       :: Sporulating
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. R37654
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000381025.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 01:54:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,193
            CDSs (total)                      :: 6,120
            Genes (coding)                    :: 6,022
            CDSs (with protein)               :: 6,022
            Genes (RNA)                       :: 73
            rRNAs                             :: 6, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 1, 3, 1 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 98
            CDSs (without protein)            :: 98
            Pseudo Genes (ambiguous residues) :: 0 of 98
            Pseudo Genes (frameshifted)       :: 37 of 98
            Pseudo Genes (incomplete)         :: 75 of 98
            Pseudo Genes (internal stop)      :: 11 of 98
            Pseudo Genes (multiple problems)  :: 20 of 98
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:55:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 18535
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB905813.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405920
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Nikos  Kyrpides (nckyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-PGF and JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18535
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..18535
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18535
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2717:4535](-)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2718..4535)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     rRNA            145..261
                     /db_xref="RFAM:RF00001"
                     /gene="rrf"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="F603_RS0100005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /product="5S ribosomal RNA"
     gene            145..261
                     /gene="rrf"
                     /locus_tag="F603_RS0100005"
     gene            502..1347
                     /locus_tag="F603_RS0100010"
     CDS             502..1347
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905151.1"
                     /locus_tag="F603_RS0100010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_019543976.1"
                     /transl_table=11
                     /translation="MTVAVRSRGGEETAVAGVTGRAVDATTVGTDRVGVVVRGTTSGAV
                     APVVTTGGARSGRSDVTAVHTVSGTGARAAVATGAVTATGVARGVRIAGTTATVTVGRG
                     PTSGMSVRDGVPMDSVTSAGTAVVVGTTGGGLVGTTAVVGAMESRAVADGSMRSGVAVG
                     VPGTTAGAVGDGSGMTGGAAETTGDVAGVGSAMTVDVMVAGPGTTVDVMVAGSAMTVDV
                     MVAGSAMTVDVVEGGSGTIGAGAPGSVVVVVGSGRIGGIVGRGLGMSGSLCGGCRFPRT
                     "
     gene            1326..>2003
                     /locus_tag="F603_RS31290"
                     /pseudo=""
     CDS             1326..>2003
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003977032.1"
                     /locus_tag="F603_RS31290"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPIPEDVSVEELDRDVRQELMSLPKTLAEDVGRNLVMVARLLDEE
                     PELAYKHAKIALRLASRVPSVREAAGFAAYAVQKYAEALAEFRAARRMTGLQHLWPVMA
                     DCERGLGRPEKALAMAGEPEVKQLDKAGQVEMRLVAAGARRDLGQPEAAVVTLQSQELA
                     SNSTQPWAARLRYAYADALLEVGREDEAREWFAKTVESDQNGVTDASDRLAELDGVEFV
                     DALD"
     gene            complement(2718..4535)
                     /locus_tag="F603_RS0100020"
     CDS             complement(2718..4535)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905153.1"
                     /locus_tag="F603_RS0100020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_019543978.1"
                     /sec_met_domain="IucA_IucC (E-value: 6e-77, bitscore:
                     254.2, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPRTDDPQQAAAHLTPERWARANRLLIRKALAEFSHERLLAPE
                     QRSAPGDVPHQYAVRSDDGATEYRFTARLAALDHWQIDADSVTRHRDGAELPLDALEFI
                     TEVRGALGLGTEILPVYLEEISSTLAGTAFKLTKPETTAAELAAADFQSVESGMTEGHP
                     CFVANNGRLGFDLAEYHAYAPEAGEPVRLLWLAAHRDRADFHTSADLSYDKLVRTELSG
                     ATLRRFSATMQELGLDLDDYYLIPVHPWQWWNKLTVTFAAEVARRHLVCLGHGDDDHLA
                     QQSIRTFFNASNPQKHYIKTALSVLNMGFLRGLSASYMEATPAINDWLADLIAEDDVLR
                     DTGLAVLRECATVGYHPAAYEAAAPKGSPYLKMLAALWRESPVPLLAPGERLATMASLL
                     HTDHAGDSYAGALIARSGLPAATWFRRYLDAYLTPLLHAFYAYDLVFMPHGENVILVLD
                     EQGAPQRAIFKDLAEEIAVMSEDAVLPPEVERVRAADVPEDVKVLSLQTDIFDCFFRFL
                     NGILASEGVLDEDTFWSTVAECIRDYQKSNPHLAERFRRYDLFTDEFALSCLNRLQLRN
                     NREMVDLQDPSGALQLVGNLHNPLARFRP"
     gene            complement(4532..5107)
                     /locus_tag="F603_RS0100025"
     CDS             complement(4532..5107)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019543979.1"
                     /locus_tag="F603_RS0100025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_019543979.1"
                     /transl_table=11
                     /translation="MTDDIRFRYEDPQLGEFALRPVAPEADAPLLHSWLTHPKSAFWLM
                     QEARLDDVAAEFGKVAASPHIEALLGLHRGEPAFLTERYDPSRIELAGLYPHRSGDAGM
                     HFLCAPTGTPLHGFTLAVITTVMASLFSDARVQRVVVEPDVRNTAVHALNRAVGFEEIG
                     EITKPEKQALLSICTRARFEAATGVTSA"
     gene            complement(5104..6477)
                     /locus_tag="F603_RS0100030"
     CDS             complement(5104..6477)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080: lysine/ornithine N-monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905155.1"
                     /locus_tag="F603_RS0100030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lysine N(6)-hydroxylase/L-ornithine
                     N(5)-oxygenase family protein"
                     /protein_id="WP_019543980.1"
                     /transl_table=11
                     /translation="MPTPHPRTAQDDAAIHDFVAVGLGPFNLGLACLTEPIEELDGLFL
                     DERDDFCWHPGMLLDDSTLQTPFLSDLVTLADPTSPYSFLNYLKEHGRLYPFYIRESFY
                     PLRSEFSDYCNWAANRLSSVRFGHRVTEVVWSEEESAYTLHVELSSGGSRTYRARRLVL
                     GTGTPPYVPEHCRDLGGDAVHNSRYLERREELRAKKSVTIVGSGQSAAEIYHDLLQECA
                     DDTYELTWITRSPRFFPLEYTKLTLEMTSPEYADYFHALPEATRDALVAGQKNLYKGIN
                     GDLIDDIFDLLYRKNRRGRTPTRLLTNTALTDASWDEATGRYTLALRQEEQQEEFTHTT
                     DGLVLATGYRYREPEFLAPVQHRIDRDPQGRFAVRRDYRIDTPQQPHGALYVQNAELHT
                     HGFVSPDLGMAAYRNSCIIRDMLGREHYPVERRIATQEFGAPGTPGTYTADPEGAASR"
     gene            complement(6505..8028)
                     /locus_tag="F603_RS0100035"
     CDS             complement(6505..8028)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019543981.1"
                     /locus_tag="F603_RS0100035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_019543981.1"
                     /transl_table=11
                     /translation="MSSRSHLLNDRTAETYRRRVTDGVERIAGRLAGTQRPFTGITPDA
                     LAPTVSAPDLENPLGDTTAALDELEDVYLRDAVYFHHPRYLAHLNCPVVIPAVLGEAVL
                     SAVNSSLDTWDQSAGGTLIEQRLIDWTAQRLGLGDAADGVFTSGGSQSNLQALLLAREE
                     AVLLARKRAEAAGAEGGIVPSTADLLPRLRILTSTCSHFSVEKSAKLLGLPHGAVVPVP
                     CDDDRRMRPAALAAELERCAAEDATVMAVVATAGTTDFGSIDPLPRIADLCAQYGTWLH
                     VDAAYGCGLLVSRRRGMLDGISRADSVTVDYHKSFFQPVSSSAVLVRDRATLRHATYHA
                     DYLNPEHSAHRRIPNQVDKSLQTTRRFDALKLWLTLRVMGPDGVGELFDEVVDRAAEAG
                     RLLAADPRFELVTAPQLSTLVFRWVPDSDPLMDAKDVDHANLHAREALFASGDAIVAGT
                     VVDGRHWLKFTLLNPETTLDDISAVLDLIAGHAQRHVDDHAHALSATAC"
     misc_feature    8074..8092
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 29.03"
                     /tool="antismash"
     misc_feature    complement(8079..8097)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.85"
                     /tool="antismash"
     misc_feature    complement(8256..8271)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.88"
                     /tool="antismash"
     gene            complement(8286..9587)
                     /locus_tag="F603_RS0100040"
     CDS             complement(8286..9587)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905157.1"
                     /locus_tag="F603_RS0100040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1015 family protein"
                     /protein_id="WP_019543982.1"
                     /transl_table=11
                     /translation="MAAEGLRLTPFRGLRYAPDRVGSLAAVTSPPYDVVVRPDGLHHLE
                     TANPYNIVRLILPHGPNGSPAAHHTQAARTLNEWRESGVLRRDARPALYVYEQRTRSVL
                     QRGLVGALQLPRSEGVVLPHEEVIDEVVADRAALMEAIAANPEPLLLSYRGAAETTGAA
                     AVIERAVHGTPLLATTTEDGTEHRLWAVTDPAELAEAAGDLAHRTALIADGHHRWATYL
                     RLRDAHAPAGAGERSPWESGLVLLVDTDRYPLQVQAIHRVLPRLPLQRALDLAAPHFRV
                     RALHVPLPQAAHALRETPGNAYLLTEDGETFHLLDAPEPGLLARTVRTDRPEAWRSLDA
                     TVLHSTLLDSVWHVQDVSGTIEYLHNTSAAIAKAASWGGTAVLMRPVAESTVRELAEQG
                     VTMPRKSTSFGPKPATGLVLRTLDGTGAGEPSSS"
     gene            9693..10763
                     /locus_tag="F603_RS0100045"
     CDS             9693..10763
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905158.1"
                     /locus_tag="F603_RS0100045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD hydrolase-like protein"
                     /protein_id="WP_019543983.1"
                     /transl_table=11
                     /translation="MVSSQAAKGAEPPADRTEPSARALGSIHDTALLDLDGVVYTGGEA
                     VPHAVRSLEAARAEGMALAYVTNNAARPRETVAEHLTELGIPAEPSDVITSAQAVARLV
                     AEQVPEGARVLCIGGEGLGLALRERGLVPVESADDEPAAVVQGYGGSTMEWGRLIEASL
                     AVGRGVPWFASNTDLTLPGSRGISPGNGAAVEVVRIATRWMRTPPEPQVAGKPLPPMHR
                     ETILRTGAQRPLVVGDRLDTDIEGAYAGGVPSLLVLTGVTDGAQLLAAPPAHRPTYVAA
                     DLRGLLEPHPRVDVGEDGAGTCGGWRARLAGDELALEGEGEPIDGLRALCAAAWSAAGA
                     GSCRADAGKALGRLGI"
     gene            complement(10804..11697)
                     /locus_tag="F603_RS0100050"
     CDS             complement(10804..11697)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0055072 - obsolete iron ion homeostasis
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905159.1"
                     /locus_tag="F603_RS0100050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="siderophore-interacting protein"
                     /protein_id="WP_019543984.1"
                     /transl_table=11
                     /translation="MTVSATEAPAPAVPFEFFELQVVRKQRIGASMVRLTFGGAQLGRL
                     VSGGKDQRFKLFLPHPGQQAPVVPTASDNWFSEWRAMDPGVRALMRTYTVRALRRTPQY
                     PADELDVDFALHEGPVPGGGPASQWALNASLGDPVTLLAPVVEDNGGVDFRPPPATDWV
                     LLSGDETALPAIASILESLPAGTPARVFLEVPHPEDRQPLLTSADAEITWLVREGEERH
                     RTEAAVAAVRETSLPSGTPYAWIAGEAGTVKALRRHLVRERGVDRRAVKFTGYWRLGIS
                     EEQLLAEATANAPAAA"
     misc_feature    11813..11831
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.56"
                     /tool="antismash"
     misc_feature    complement(11818..11836)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 28.73"
                     /tool="antismash"
     misc_feature    11833..11846
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    11838..11847
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.82"
                     /tool="antismash"
     gene            12078..12386
                     /locus_tag="F603_RS0100055"
     CDS             12078..12386
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905160.1"
                     /locus_tag="F603_RS0100055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_019543985.1"
                     /transl_table=11
                     /translation="MSELTPGASPAAQGAETEAPGGPEAEQADRSAGAEPGEAADDGPR
                     PLGVTVTPTGHGPVDARLARLADADHLAVSGHLEVYEDVHSGLRETLAALDRPTPRS"
     gene            12390..13196
                     /locus_tag="F603_RS0100060"
     CDS             12390..13196
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018558900.1"
                     /locus_tag="F603_RS0100060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_019543986.1"
                     /transl_table=11
                     /translation="MARRRLDAELVRRRLARSREHASQLIAAGRVTVGGNPAAKPATQV
                     ETSAPLVVTEDSDDPQYVSRGGHKLAGALEAFAPHGLRVDGRRALDAGASTGGFTDVLL
                     RAGAESVVAVDVGYGQLAWSLRSDTRVTVKDRTNVRELTPEVLEGRPADVVVGDLSFIP
                     LGLVLPALVRCAAPGADLVLMVKPQFEVGRERLGSGGVVRSSQLRAEAVRTVAGQAAEQ
                     GLGVLGIAASPLPGPSGNVEYFLWLRAGAPALDPADVERAVAEGPK"
     gene            13193..14113
                     /locus_tag="F603_RS0100065"
     CDS             13193..14113
                     /EC_number="2.7.1.23"
                     /GO_function="GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019674 - NAD metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019543987.1"
                     /locus_tag="F603_RS0100065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD kinase"
                     /protein_id="WP_019543987.1"
                     /transl_table=11
                     /translation="MTASTETGDRTVFLLAHTGRPAAVRSAELVVQGLLRSGLGVRLLG
                     EEAVDLPLPREVEAVEAKPDAAEGCELLVVLGGDGTLLRGAEFARASGVPMLGVNLGRV
                     GFLAEAERDDLDQVVERVAHRSYEVEERMTIDVLVRSEGRAVHTDWALNEASVEKAARE
                     RVLELVTEVDDRPVSAFGGDGVVCATPTGSTAYAFSAGGPVVWPEVEALLMVPISAHAL
                     FAKPLVTSPESVLAVEVQPQTPHGVLWCDGRRSVELPPGARVEVRRGAVPVRLARLHHA
                     SFTDRLVAKFALPVAGWRGAPRGDG"
     gene            14227..15969
                     /gene="recN"
                     /locus_tag="F603_RS0100070"
     CDS             14227..15969
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905163.1"
                     /locus_tag="F603_RS0100070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA repair protein RecN"
                     /protein_id="WP_019543988.1"
                     /transl_table=11
                     /translation="MVVSVLEEMRIRALGVIDDAALTLSPGFTAVTGETGAGKTMVVTS
                     LGLLLGGRADAALVRVGAKAAVVEGRVALPADAPAARRAEEAGAELDDGELLLSRTVSA
                     EGRSRAHVGGRSVPVGLLAELKDDLVAVHGQTDQQGLLRPARQREALDRYAGEAVSGLL
                     SEYGDLYRRLRSVNDELTEITTRARERAQEADMLRFGVDEISAAEPQAGEDRELAAEAE
                     RLGHAEALAEAAATAHGALAGDPAEPEGLDANTLVAGAQRALDGARAHDPALAALADRL
                     GEVSVLLGDVAGELAGYADDLDADPLRLAAVEERRATLAGLTRKYGEDIAAVLAWAEES
                     SARLAELEGDDDRVGELTAERDRLRAELGVLAHRLTQARQEAAERFADAVTAELAELAM
                     PHAQVTFGLRQTDDPEGLEVEGRTLAYGPHGTDEVELLLAPHPGAHPRPIAKGASGGEL
                     SRVMLAVEVVFAGADPVPTYLFDEVDAGVGGRAAVEVGRRLAKLAESAQVVVVTHLPQV
                     AAFADRHLVVVKTDDGSVTRSGVQVMEGEERVRELSRMLAGQDDSELARAHAEELLDAA
                     RAGG"
     gene            16300..16890
                     /locus_tag="F603_RS0100075"
     CDS             16300..16890
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010638463.1"
                     /locus_tag="F603_RS0100075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_019543989.1"
                     /transl_table=11
                     /translation="MPRRALENPIALAVLGLLLESSSHPHQILAELRKRSDNQAAVLSR
                     GTLYHTVAALAGAGWVASQGQQRSGNRPEKTVYALTLAGREELVRRLDAQIRTPQREFS
                     RFLGAVTYLGALGKDGALEALDERARRLRERTAADETRLAEAHAAGVPRLHVIEAEYAL
                     HLARAETEWIDTVTDDIRSGALAWPPHRKGPQR"
     gene            16857..17870
                     /locus_tag="F603_RS0100080"
     CDS             16857..17870
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019524661.1"
                     /locus_tag="F603_RS0100080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_019543990.1"
                     /transl_table=11
                     /translation="MATAQEGAAAMTRRTGLLFGIYPGGVAGDDSGSLAAGPPDEPAPA
                     AAALDRLQGRPGRPFLVRAYTGFDDTTRLGGPHATEAPADAARYAVRGRRLDLVAQYRS
                     GSADVEGYCAFLRELVEQYGAFTETLQVAEEPNVTDNPVLDGYYPAVREAIVCGVPVAK
                     ARARELGHHHLRVGCNSTPLFGPAAGFFTDLAAAGGADFPAQLDYVGLDFFPDVFRPVA
                     PSELAATVSGLLRHHRETVLAPAGLGHLPLHVTEHGWPTGPERSAARQAEVVETVVDVL
                     AAHAAPLGVSGYTHFALRDADSTRSGLFHRFGLTTDDYTPKPAFETLRALVERYSV"
     misc_feature    18370..18384
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 aataggccga gggcttgtcc atagaggctt cgcgtccact gtgcagttct gaaacaacga
       61 acggctgctt cggttctatc tgaagagtgt gttgttcgct cggcccggta gcgcgtgcgt
      121 gtgtcacggc gtgtgggtga gtgtttcggt ggttatagcg tgagggaaac gcccggtcac
      181 atttcgaacc cggtagctaa gcctttctgc gccgatggta ctgcatacgg gagtgtgtgg
      241 gagagtagga caccgccgaa ctattagtga ggcccctggc ccccagcgtt cagacgctgg
      301 aggccagggg ccttttttgt tttgttggtc tgcgccgtcc gctgcggttc atgtacggaa
      361 ggcgccgtac cgcgtgctgc gtgagaatga atgtgcagca gccgcagaca ggagtcatct
      421 cgatgtccac caactcgccg gaggatcggc cgccgcgtcg ttcggatcag tccgggtacc
      481 agcgcggcga ggaccgcgcg cgtgacggtc gccgtgagga gcagaggcgg ggaagagacg
      541 gcggtcgcgg gggttaccgg ccgggcggtg gacgcaacga ccgtcgggac ggaccgcgtt
      601 ggcgtggtgg ttcgggggac gacgagcggg gccgtggctc ccgtcgtgac gaccggcggg
      661 gcgaggagcg gccggagcga cgtgaccgca gtacatacgg tgagcgggac aggagccagg
      721 gccgcggtgg ctacgggggc cgtgacggcg accggggtcg cgaggggcgt ccgtatcgcc
      781 gggacgaccg cgaccgtgac cgtggggaga ggccctacaa gcgggatgag cgtgagggac
      841 ggcgtcccta tggacagcgt gacgagcgcg gggacggccg tggtcgtcgg gacgacgggc
      901 ggggggctcg tcgggacgac cgcggtggtg ggcgcgatgg agagcagggc cgtagccgac
      961 ggttcgatga ggagcggggt cgcggtgggc gtcccgggga cgaccgcggg cgcggtgggg
     1021 gacggttccg ggatgacagg gggcgcggcg gagacgaccg gggacgtggc gggggtcggt
     1081 tccgcgatga ccgtggacgt gatggtggcc ggtcccggga cgaccgtgga cgtgatggtg
     1141 gccggttccg cgatgaccgt ggacgtgatg gtggccggtt ccgcgatgac cgtggacgtg
     1201 gtggagggcg gttccgggac gatcggggcg ggcgctccgg ggagcgtcgt ggtggtggtc
     1261 ggttcgggga ggatcggcgg gatcgtgggc agggggctcg gcatgagcgg gagcctgtgc
     1321 ggaggatgcc gattcccgag gacgtgagcg tcgaggagtt ggatcgggat gtcaggcagg
     1381 agttgatgag cctgccgaag actctcgccg aggatgtcgg gcggaatctg gtgatggttg
     1441 cgcgtctgct cgacgaggag cccgaactcg cctacaagca cgccaagatc gcgttgcggc
     1501 tcgcttccag agtgccgtcc gtgcgggagg cggccgggtt cgcggcgtat gcggtgcaga
     1561 agtatgccga ggcgttggcc gagttccggg ctgctcgacg tatgacgggc ctccagcacc
     1621 tctggcccgt gatggccgac tgcgagcgcg gactggggcg tccggaaaag gcattggcga
     1681 tggccggtga gcccgaggtc aagcagttgg acaaggcggg gcaggtcgag atgcgcctcg
     1741 tcgctgcggg ggcccggcgt gacctggggc agcccgaggc cgcggtggtg acgttgcaga
     1801 gtcaggagct ggcgtcgaac tccactcagc cgtgggctgc caggctgcgt tacgcgtatg
     1861 cggacgcgct gctggaggtc ggcagggagg acgaggcccg cgagtggttc gccaagacgg
     1921 tcgagtccga ccagaacggg gtgaccgacg cctcggaccg cctcgctgag ctcgacgggg
     1981 tggagttcgt ggacgcgctc gaccccgaag ccgaggaggc agcggacacc gagccggtcg
     2041 atgaggcccg cacgtcgagc cgggagcagc gggccgaggc cctgcgccag gtgcacggag
     2101 actcgcccag aaccgatgcc aactccacca ccgcacaggc aggttcgggc tcctccgacg
     2161 cggggtcgga gcgggacgtc gaggcgaaga gtgagtccag gggcgccggc gctgacgccc
     2221 gggagggtgg cgaggcagcg gcctcgggga cggagagcaa cgacgggccg aaggccgagg
     2281 acggtccggg tccggtagat gacagcgcag atttcgagag cgaccagtct gctgagagtg
     2341 acgtgcggtc cggtggcggc ctaggtaccg gcagggacgg cgccggttcc gagagtggca
     2401 tgcggtccga gggtggcccg ggtgccgatg accgtggcgc aggtcctgag agcgggcagg
     2461 gtgctgaggg cggcccggat gccactggtg acggtgcggg ttccgagggc ggacggagcg
     2521 aggacggcct tggttatggg gccggttcgg gtgtgggaag cgaggcggag agttccgagg
     2581 acggtgggga gcgccgggac tgaggacggt ttggtcgcct ggttcaggcg gtgaggatgg
     2641 gcacggcccc gggctcggtt gagctcgggg ccgttttctg agggaggctg cgcaggtgtt
     2701 gagcgcggaa gggcgagtca ggggcggaag cgggcgaggg ggttgtggag gttgccgacc
     2761 agttggagtg cgcccgaggg gtcctggagg tcgaccatct cgcggttgtt gcggagctgg
     2821 aggcggttga ggcaggagag cgcgaactcg tcggtgaaca ggtcgtagcg gcggaagcgt
     2881 tcggcgaggt gcgggttgga cttctggtag tcgcggatgc actcggcgac cgtcgaccag
     2941 aaggtgtcct cgtcgagtac gccttcggag gcgaggattc cgttgaggaa ccggaagaag
     3001 cagtcgaaga tgtcggtctg gagcgagagg accttcacgt cctcggggac gtcggccgcg
     3061 cggacgcgct cgacctcggg cgggagtacg gcgtcctcgc tcatcaccgc gatctcctcg
     3121 gccaggtcct tgaagatggc ccgctgcggt gcgccctgtt cgtcgaggac gagaatcacg
     3181 ttctcgccgt gcggcatgaa gacgaggtcg tacgcgtaga aggcgtggag gagcggagtg
     3241 aggtaggcgt cgaggtagcg ccggaaccag gtggcggcgg ggaggccgct gcgggcgatg
     3301 agggcgccgg cgtaggagtc gcccgcgtgg tcggtgtgga ggagcgacgc catggtcgcg
     3361 aggcgctcgc ccggtgcgag gagcggcacg gggctctcgc gccacagggc tgcgagcatc
     3421 ttgaggtacg gggagccctt gggggccgct gcctcgtacg ctgccgggtg gtagccgacg
     3481 gtggcgcact cgcggaggac ggcgaggccg gtgtcgcgga ggacgtcgtc ctcggcgatg
     3541 aggtcggcga gccagtcgtt gatggccggg gtcgcctcca tgtacgaagc cgaaaggccg
     3601 cgcaggaagc ccatgttgag gacggagagc gccgtcttga tgtagtgctt ctgcgggttg
     3661 ctggcgttga agaaggtgcg tatcgactgc tgtgccaggt ggtcgtcgtc gccgtggccg
     3721 aggcagacga ggtggcgccg ggccacctcg gcggcgaacg tcacggtgag cttgttccac
     3781 cactgccagg ggtggacggg gatgaggtag tagtcgtcga ggtcgaggcc gagttcctgc
     3841 atcgtggcgg agaagcggcg gagggtggcg cccgagagct cggtgcggac gagcttgtcg
     3901 tagctgaggt cggcggaggt gtggaagtct gcgcggtcgc ggtgcgcggc gagccagagg
     3961 aggcggacgg gctcgccggc ctcgggtgcg taggcgtggt actcggcgag gtcgaagccg
     4021 agccggccgt tgttggcgac gaagcagggg tggccctcgg tcatgccgga ctcgacggac
     4081 tggaagtcgg cggcggcgag ttcggcggcg gtggtctcgg gcttggtgag cttgaacgct
     4141 gtgccggcga gggtgctgct gatctcctcg aggtagacgg ggagtatctc cgtgccgagg
     4201 ccgagggcgc cgcgtacctc ggtgatgaac tccaaggcgt ccagagggag ttcggcgccg
     4261 tcgcggtggc gggtgacgga gtcggcgtcg atctgccagt ggtcgagggc ggcgaggcgg
     4321 gcggtgaagc ggtactcggt ggcgccgtcg tcgctgcgga cggcgtactg gtgcggtacg
     4381 tcgccggggg ccgaccgctg ctcgggggcg aggaggcgct cgtgcgagaa ctcggcgagc
     4441 gccttgcgta tcaggaggcg gttggcgcgg gcccagcgct cgggggtgag gtgggccgct
     4501 gcctgctgcg ggtcgtcggt gcggggggtg gtcatgctga agtcactcct gtggcggcct
     4561 cgaatcgggc gcgggtgcag atgctgagca gggcctgctt ctccggcttg gtgatctccc
     4621 cgatctcctc gaacccgacg gccctgttga gcgcgtgcac ggcggtgttg cggacgtcgg
     4681 gttcgacgac gacgcgctgc acgcgcgcgt cggagaagag ggacgccatc accgtggtga
     4741 tgaccgcgag ggtgaagccg tggagcgggg tgccggtcgg tgcgcagagg aagtgcatgc
     4801 cggcgtcgcc gctgcggtgc gggtagaggc cggccagttc gatccgcgag gggtcgtacc
     4861 gttcggtgag gaaggcgggc tcgccgcggt ggaggccgag aagggcctcg atgtgcggcg
     4921 aggcggcgac tttgccgaac tccgcggcga cgtcgtcgag tcgggcctcc tgcatgagcc
     4981 agaaggccga cttggggtgc gtgagccagg agtgcagcag gggcgcgtcg gcttccgggg
     5041 cgaccgggcg cagcgcgaac tcgcccaact gcgggtcctc gtagcggaat cggatgtcgt
     5101 cggtcatcgg ctggctgctc cctcggggtc tgctgtatag gtgcccggtg tgccgggggc
     5161 gccgaactcc tgtgtggcga tgcgacgttc gacggggtag tgctcgcggc cgagcatgtc
     5221 ccggatgatg caggagttgc ggtacgcggc catgccgagg tcgggggaga cgaagccgtg
     5281 ggtgtgcagc tccgcgttct gcacgtagag ggcgccgtgg ggctgctgcg gggtgtcgat
     5341 gcggtaatcg cggcgtacgg cgaaccggcc ctgggggtcg cggtcgatgc ggtgctggac
     5401 gggggcgagg aactccggtt cgcggtaccg gtatccggtg gcgaggacga ggccgtcggt
     5461 ggtgtgggtg aactcctcct gctgctcctc ctggcgcagc gcgagggtgt acctgccggt
     5521 ggcctcgtcc caactcgcgt cggtgagcgc agtgttggtg aggagcctcg tcggggtgcg
     5581 gccgcgtctg ttcttgcggt agagcaggtc gaagatgtcg tcgatcaggt cgccgttgat
     5641 gcccttgtag aggttcttct ggccggcgac gagggcgtcc ctggtggcct cggggagcgc
     5701 gtggaagtag tcggcgtact cgggggaggt catctccagc gtgagcttgg tgtactccag
     5761 cgggaagaac ctcggggagc gggtgatcca ggtgagctcg taggtgtcgt cggcgcactc
     5821 ctggagcagg tcgtggtaga tctcggcggc gctctgcccg ctgccgacga tcgtgacgct
     5881 cttcttggcg cgcagctctt ccctgcgctc caggtaccgg gagttgtgca cggcgtcgcc
     5941 gccgaggtcg cggcagtgct cggggacgta cggcggggtg ccggtgccga ggacgaggcg
     6001 gcgggcgcgg taggtgcggc tgccgccgga ggagagctcg acgtggaggg tgtacgccga
     6061 ctcctcctcg ctccagacga cttcggtgac ccggtggccg aagcgaaccg aactcaacct
     6121 gttcgccgcc cagttgcagt agtcgctgaa ctcggagcgc agcgggtaga agctttcgcg
     6181 gatgtagaac gggtacagtc ggccgtgttc cttcaggtag ttgaggaagg agtacggcga
     6241 ggtggggtcc gcgagggtga cgaggtcgga gaggaagggc gtctgaaggg tgctgtcgtc
     6301 gagcagcatc cccgggtgcc agcagaagtc gtcgcgctcg tcgaggaaga gtccgtccag
     6361 ctcctcgatg ggttcggtga ggcaggccag cccgaggttg aaggggccga ggccgacggc
     6421 gacgaagtcg tggatcgcgg cgtcgtcctg cgccgtgcgg gggtgcgggg tgggcacgtg
     6481 aactccgggg gatcgggggg cggttcagca ggctgtggcg ctgagcgcgt gcgcgtggtc
     6541 gtcgacgtgg cgctgggcgt gcccggcgat caggtcgagg acggcggaga tgtcgtcgag
     6601 cgtcgtctcg gggttgagga gcgtgaactt cagccagtgc cggccgtcga cgacggtccc
     6661 cgcgacgatc gcgtcgcccg aggcgaagag ggcttcccgc gcgtggaggt tggcgtggtc
     6721 gacgtccttc gcgtccatca gcgggtcgga gtccgggacc cagcggaaga cgagggtgga
     6781 gagctgcggc gccgtcacga gctcgaaccg cgggtcggcg gcgagcagcc ggccggcctc
     6841 ggcggcgcgg tcgacgacct cgtcgaagag ttcgccgacg ccgtccgggc ccatgacgcg
     6901 cagtgtcagc cacagcttga gcgcgtcgaa cctgcgggtc gtctggagcg atttgtcgac
     6961 ctgattgggg atgcggcggt gtgcgctgtg ctcggggttg aggtagtcgg cgtggtaggt
     7021 cgcgtgccgc agggtggcgc ggtcgcggac gaggacggcc gacgaactca ccggctggaa
     7081 gaaggacttg tggtagtcga cggtgaccga gtcggcgcgt gagatgccgt cgagcatgcc
     7141 gcgcctgcgg gagacgagca gcccgcagcc gtaggcggcg tcgacgtgga gccaggtgcc
     7201 gtactgcgcg cagaggtcgg cgatgcgggg gagcggatcg atgctgccga agtccgtcgt
     7261 gcccgccgtg gcgacgaccg ccatcaccgt cgcgtcctcg gcggcgcagc gctccagctc
     7321 ggccgcgagg gcggcggggc gcatccgccg gtcgtcgtcg caggggacgg ggacgacagc
     7381 cccgtgcggg aggccgagga gtttcgcgga cttctccacg ctgaagtggc tgcacgtgga
     7441 ggtgaggatg cggagccggg gcagaaggtc ggcggtgctc ggcacgatcc cgccctctgc
     7501 gcctgcggct tcggcgcgtt tccgggcgag gaggacggcc tcttcgcggg cgagcagcag
     7561 cgcctggagg ttcgactgcg agccgccgct ggtgaagacg ccgtcggcgg cgtcgccgag
     7621 accgaggcgc tgcgcggtcc agtcgatgag ccgctgctcg atcagcgtgc cgccggcgct
     7681 ctggtcccag gtgtcgaggg aggagttgac ggcgctgagc acggcctcgc cgagcaccgc
     7741 cgggatgacg acggggcagt taaggtgggc gaggtaccgg gggtggtgga agtagacggc
     7801 gtccctgagg tagacgtctt ccagttcgtc gagcgcggcg gtcgtgtcgc ccagcgggtt
     7861 ctccaggtcg ggtgccgaga cggtcggggc gagcgcgtcc ggcgtgatgc ccgtgaacgg
     7921 gcgctgggtg ccggcgagtc tgccggcgat ccgctcgacg ccgtccgtga cacggcgccg
     7981 gtaggtctct gccgtccggt cgttgagcag gtgtgacctg ctgctcatga actgtcctcc
     8041 tgacgcggga cgtgaaaccg ctcggctggg cggtgaggta aggctagcct aatcactcat
     8101 ttcggctgtc tcgcaaggcc gccctgcggc agcggcgcac gtcacaggcg gtgtcggttt
     8161 agcggccaac accccaacgt gctacggccg ttgggcggta atgcggtcgg tgtccacggt
     8221 gccggaccgc tgtgctgctg tgcagccggt gctgttgtga gcgatctccc acggaggtac
     8281 gggagttacg aagaggaagg ctctccggcg cccgtcccgt cgagggtgcg caggaccagc
     8341 cccgtggccg gcttggggcc gaacgacgtc gacttcctcg gcatcgtgac gccctgctcg
     8401 gcgagttcgc ggacggtcga ctcggcgacg ggacgcatga ggacggccgt cccgccccag
     8461 gatgcggcct tggcgatcgc cgccgaggtg ttgtgcaggt actcgatcgt gccggagacg
     8521 tcctggacgt gccagacgga gtcgaggagc gtcgagtgga gcaccgtcgc gtcgagggag
     8581 cgccatgcct cgggacggtc ggtgcgcacg gttcgcgcga gaagtccggg ttccggggcg
     8641 tcgaggaggt ggaaggtctc gccgtcctcc gtgagcaggt aggcgttgcc cggtgtctcg
     8701 cggagcgcgt gggccgcctg cggcagcggg acgtgcagcg cgcgtacccg gaagtgcggt
     8761 gcggcgaggt cgagggcccg ttgcaggggg agccggggca ggacgcggtg gatcgcctgg
     8821 acttggagcg ggtagcggtc ggtgtcgacg aggaggacga ggcccgactc ccagggggag
     8881 cgctccccgg cgccggccgg cgcgtgtgcg tcgcggaggc gcaggtacgt cgcccagcgg
     8941 tggtggccgt cggcgatgag cgccgtccgg tgggcgagat cccctgcggc ttcggcgagt
     9001 tcggccgggt ccgtcaccgc ccacaggcgg tgctcggtgc cgtcctcggt ggtggtggcg
     9061 aggaggggcg tgccgtgcac ggcgcgttcg atcaccgctg ccgcgcccgt cgtttcggcg
     9121 gctccccggt aggagaggag gagcggttcg gggttggcgg cgatagcttc catcagcgcc
     9181 gcgcggtcgg cgacgacctc gtcgatgacc tcctcgtggg ggagtacgac gccttcgctg
     9241 cgcggcagtt gcagggcgcc gacgaggccg cgctggagca ccgagcgcgt gcgctgctcg
     9301 tagacgtaga gcgcggggcg cgcgtcccgg cgcagcacgc cgctctcgcg ccactcgttc
     9361 agcgtgcgcg cggcctgggt gtggtgggcg gcgggagagc cgttggggcc gtgcgggagg
     9421 atgaggcgga cgatgttgta cggattggcc gtctccaggt ggtgcaggcc gtcgggccgt
     9481 acgacgacgt cgtacggcgg agaggtgacc gcggcgaggc tgccgacccg gtccggggcg
     9541 taacgcaacc cgcggaacgg ggtgagtctc agtccttctg cggccatcgg tgcatgctat
     9601 gcctcttccg gcaggcaggg gaaaaccggg caccgcaggc ccgcgcagcc gcgcgggcag
     9661 accacacgag cacgtgcaag gagcagacga cgatggtgag ttcgcaggca gcgaagggcg
     9721 ccgagccgcc cgcggaccgt acggagccga gcgcccgggc gctcgggagc atccacgaca
     9781 ctgcgctcct cgacctcgac ggcgtcgtct acaccggcgg ggaggccgtg ccgcacgccg
     9841 tccgctcgct ggaggcggca cgcgccgagg ggatggcgct ggcgtacgtg accaacaatg
     9901 cggcgcgccc ccgggagacg gtcgccgagc acctcaccga actcggtatc cccgccgagc
     9961 cgtcggacgt catcacctcg gcacaggcgg tcgcgcggtt ggtcgcggag caggttcccg
    10021 aaggcgcacg ggtgttgtgc atcggcggcg agggcctcgg cctggccttg cgcgaacgcg
    10081 ggctcgtccc cgtggagtcg gccgacgacg agccggccgc agtcgtccag gggtacggcg
    10141 ggtcgacgat ggagtggggc aggctcatcg aggcgtcgct cgcagtgggc cgcggtgtgc
    10201 cgtggttcgc ctccaacacc gacctcaccc tcccgggcag ccggggcatc tcgccgggca
    10261 acggtgcggc cgtcgaggtc gtgcggatcg cgacccggtg gatgcgcacg ccgcccgaac
    10321 cgcaggtggc ggggaagccg ctgccgccga tgcaccggga gacgatcctg cggacaggtg
    10381 cccaacggcc gctggtcgtc ggcgatcggc tcgacaccga catcgagggg gcgtacgccg
    10441 gcggggtccc ctcgctgctc gtcctcacgg gggtgacgga cggcgcgcag ctcctcgccg
    10501 cgccccccgc acaccgcccg acgtacgtcg cggccgacct gcgcgggctg ctggagccgc
    10561 acccccgagt cgacgtcgga gaggacggcg ccgggacgtg cgggggttgg cgcgcccgcc
    10621 tcgccggtga cgagctggcg ctcgagggcg agggcgagcc gatcgacggg ctccgtgcgc
    10681 tgtgcgccgc cgcgtggagc gctgcgggag cgggcagttg ccgcgccgat gcggggaagg
    10741 cgctcgggcg gctgggcatc tagcggcgcc cccacggcac gggggcgccg gtgatggtga
    10801 acgtcaggcg gcggcgggcg cgttggcggt cgcctcggcg aggagctgct cctcgctgat
    10861 gccgagccgc cagtagccgg tgaacttcac ggcgcgcctg tcgaccccgc gctcacgtac
    10921 gaggtgcctg cggagcgcct tgacggtgcc ggcctcgccc gcgatccacg cgtagggcgt
    10981 gccggagggg aggctcgtct cccgaacggc ggcgacggcg gcctcggtgc ggtggcgctc
    11041 ctcgccctcg cgcacgagcc aggtgatctc ggcgtcggcc gaggtgagca ggggctgccg
    11101 gtcctcgggg tgcgggacct cgaggaagac ccgggccggg gtgcccgccg ggagggactc
    11161 cagaatcgac gcgatcgccg gcagcgccgt ctcgtcgccg ctgagcagga cccagtcggt
    11221 ggcgggcggg ggacggaagt cgacgccgcc gttgtcctcg acgacgggcg ccagcagcgt
    11281 gaccgggtcg ccgagggagg cgttgagcgc ccactgcgag gcggggccgc cgccggggac
    11341 ggggccctcg tggagggcga agtcgacgtc gagttcgtcg gccgggtact gcggcgtgcg
    11401 ccggagtgcg cggacggtgt acgtgcgcat gagtgcgcgg acgcccgggt ccatggcgcg
    11461 ccactcgctg aaccagttgt cggacgcggt gggcacgacg ggggcctgct ggccggggtg
    11521 gggcaggaag agcttgaagc gctggtcctt tccgcccgag acgagccggc ccaactgtgc
    11581 gccgccgaag gtgaggcgca ccatgctggc gccgatccgc tgtttccgca cgacctggag
    11641 ctcgaagaac tcgaacggca ccgccggagc cggggcttcg gtcgccgaga ctgtcatgcg
    11701 tttcctcctt gcggcgtgca gcgcggcggg ccgtcggcgc cgagaggccg cgcctctgcg
    11761 tgcggcccgc tgtcgcgccg gactgcgggt gcgggaggtg cgatcaccaa cccgcggtta
    11821 ggttaaccta accaaaccgt tttttgtcca ggggctcagg tcccggttgc cgccgtgcac
    11881 gtgtggcgct gctcaccccg gcgggcggcc actcccaacg gaccgcgaca gagggcgagt
    11941 cggcgccgtc ccgccgggcg ccacggggta agtcgccact tccgtaaggc tcttcgcgcg
    12001 cgggcccggt tccggcgcgc caccggacgc accgccgcac cgctgcggtg cggcggcgac
    12061 cgggtagcgt cggggtcatg agcgagctga cacccggcgc gtcccccgcg gcgcagggag
    12121 cggaaacgga agcgccgggc ggaccggagg cggagcaggc ggaccggagc gcgggcgccg
    12181 agcccggaga ggccgcggac gacgggccgc ggcccctcgg cgtcaccgtc acgccgaccg
    12241 ggcacgggcc cgtcgacgcg cggctggcgc ggctggcgga cgcggaccac ctcgccgtct
    12301 ccggccatct cgaggtgtac gaggatgtcc acagcggcct gcgcgagacg ctcgccgccc
    12361 tcgaccgacc cacccctcgg agctgacccg tggcacgacg ccgactcgac gcggagctgg
    12421 tgcgccgccg gctcgcgcgc tcgcgcgagc acgcaagcca actcatcgcc gcgggacgcg
    12481 tcaccgtcgg cggcaacccc gctgcgaagc cggccaccca ggttgagacg agcgcgcccc
    12541 tcgtcgtcac cgaggactcc gacgacccgc agtacgtctc tcgcggcggc cacaaactcg
    12601 cgggcgcgct cgaggcgttc gccccgcacg gcctgcgtgt cgacgggcgc cgggcgctcg
    12661 acgccggcgc ctccacgggc ggtttcaccg acgtgctact gcgtgccggc gccgagagcg
    12721 tcgtcgccgt cgacgtgggc tacgggcagc tcgcctggtc gctgcggagc gacacccgag
    12781 tcaccgtcaa ggaccgcacg aacgtaaggg agttgacgcc cgaggtgctc gaaggccgcc
    12841 cggccgacgt cgtggtgggg gacctctcct tcatcccgct ggggctcgtc ctgcccgcgc
    12901 tggtacggtg cgcggcaccc ggcgccgatc tcgtcctcat ggtgaagccg cagttcgagg
    12961 tggggaggga acggctcggc agcggcggtg tcgtgcgcag ctcgcagttg cgcgccgagg
    13021 cggtccggac cgtggcgggg caggcggccg agcaggggct cggggtgctc gggatcgccg
    13081 ccagcccact gccggggcct tcgggcaacg tcgaatactt cctgtggctg cgcgccgggg
    13141 cacccgctct cgacccggcg gacgtcgagc gagcggtggc ggaggggccc aagtgacagc
    13201 gagtaccgaa acaggcgacc ggacggtctt cctgctcgcg cacaccgggc ggcccgccgc
    13261 cgtgcgcagc gccgaactgg tcgtccaagg gttgctgcgc agcggcctcg gggtgcggct
    13321 cctcggcgag gaggcggtgg acctgccgct tccgcgcgag gtcgaggcgg tcgaggcgaa
    13381 gccggacgcg gccgaggggt gcgaactcct cgtcgtgctc ggtggcgacg ggacgctgct
    13441 gcgcggcgcg gagttcgcca gggcctcggg cgtgccgatg ctcggcgtca acctcggccg
    13501 cgtcggcttc ctcgccgagg cggagcgcga cgacctcgac caggtcgtcg agcgcgtggc
    13561 gcaccgctcc tacgaggtgg aggagcggat gacgatcgac gtcctcgtcc gcagcgaggg
    13621 ccgcgccgtg cacaccgact gggcgctcaa cgaggcgtcc gtcgagaagg cggcgcgtga
    13681 gcgggtgctg gagctcgtca ccgaggtcga cgaccgcccc gtctccgcct tcggcgggga
    13741 cggcgtcgtc tgcgccaccc cgacgggttc caccgcgtac gccttctccg ccggcggtcc
    13801 cgtggtgtgg cccgaggtgg aggcgctcct gatggtgccg atcagcgcgc acgcgctctt
    13861 cgccaagccg ctggtcacct cgcccgagtc ggtgctcgcc gtggaggtgc agccgcagac
    13921 gccgcacggg gtgctctggt gcgacggccg gcgcagcgtc gaactgccgc ccggcgcacg
    13981 ggtcgaggtg cgccgcgggg ccgtgccggt gcggctggcg cggctccacc acgcctcctt
    14041 caccgaccgg ctcgtcgcca agttcgcgct gccggtcgcc gggtggcggg gggctccgcg
    14101 gggggacggc tgagtggtgc ggggtcgccg ttgagggtga tccggccgtc cctttcgtag
    14161 tgattcctcc gtttctgtgc cggtgctcgg acagggctgg ggtaggggcg acccccggaa
    14221 cctcgtatgg tcgtatccgt gttggaggag atgcggatca gagccctggg cgtgatcgac
    14281 gacgccgcac tcaccctgtc ccccggcttc accgcggtga cgggggagac gggcgcgggc
    14341 aagacgatgg tcgtcaccag cctcgggttg ttgctcggcg ggcgtgccga tgccgcgctg
    14401 gtgcgggtcg gggcgaaggc cgcggtggtc gaggggcgtg tcgcgctccc ggccgacgca
    14461 cctgcggcgc ggcgggccga ggaggccggc gccgaactcg acgacgggga gctgctgctg
    14521 agccgtacgg tctcggccga ggggcgctcg cgggcgcacg tcggcgggcg ctcggtcccg
    14581 gtcggtctcc tcgccgagct caaggacgac ctcgtcgccg tccacgggca gaccgaccag
    14641 cagggcctgc tgcgccccgc ccggcagcgc gaggcgctcg accggtacgc gggcgaggcc
    14701 gtctccgggc tcctctccga gtacggcgac ctctaccgcc gactccgcag cgtcaatgac
    14761 gagttgacgg agatcaccac tcgcgcgagg gagcgtgccc aggaggcgga catgctccgc
    14821 ttcggcgtgg acgagatctc cgcagccgag ccgcaggccg gcgaggacag ggaactcgcc
    14881 gccgaggccg agcgcctggg gcacgccgag gcgctcgcgg aggccgcggc gacggcgcac
    14941 ggcgcactcg cgggcgaccc ggcggagccg gagggcctgg acgccaacac gctcgtcgcc
    15001 ggcgcccagc gtgcgctcga cggcgcgcgg gcgcacgacc ccgcgctcgc cgcgctcgcc
    15061 gaccggctcg gcgaggtctc cgtcctcctc ggcgacgtcg cgggcgaact cgccggctac
    15121 gccgacgatc tcgacgccga cccgctccgc ctcgccgccg tggaggagcg ccgcgccacc
    15181 ctcgccggcc tcacccgcaa gtacggcgag gacatcgccg ccgtactcgc ctgggccgag
    15241 gagagttcgg cgcgcctcgc cgaactcgaa ggggacgacg accgggtcgg cgaactcacc
    15301 gccgaacgcg accggctgcg cgccgaactc ggcgtgctcg cacaccggtt gacccaggca
    15361 cggcaggagg ccgcggagcg gttcgccgac gccgtcacgg cggagctcgc cgaactcgcc
    15421 atgccgcacg cgcaggtgac cttcggactc cggcagacgg acgaccccga gggcctggag
    15481 gtcgagggcc gcaccctcgc ctacggcccg cacggcaccg acgaggtgga gctcctcctc
    15541 gcgccccacc cgggcgcgca cccgcgcccc atcgcgaagg gcgcctcggg cggcgagctg
    15601 tcgcgggtga tgctcgccgt cgaggtcgtc ttcgccggcg ccgaccccgt accgacctac
    15661 ctcttcgacg aggtcgacgc gggcgtcggc ggcagggccg cggtggaagt cggcaggcga
    15721 ctggcgaagt tggccgagtc ggcacaggtc gtggtcgtga cccacctgcc gcaggtggcg
    15781 gcgttcgccg accggcacct cgtcgtcgtc aagaccgacg acggctccgt gacgcgcagc
    15841 ggcgtgcagg tgatggaggg cgaggagcgg gtgcgcgaac tctcccggat gctcgcggga
    15901 caggacgact ccgaactcgc ccgcgcccac gcggaggagc tcctcgacgc cgcgcgtgcg
    15961 gggggctgag cgcgcggggg cggccctggc cgggaggggg ccgtgggtcc ggtgttgctg
    16021 tctccggaac gcctctgcgc tcgcacgctt tcgacctgcc gtgaaccgcg acgatccatc
    16081 cacccgccct gcttcctttc gggccatgca tgccgtcgcc gcgcgaccgg cgcggggctg
    16141 tcgccgcggc cgggcgcagg gcgggcttgg gagtggcgcc aagggaccgt ggtgtcaccg
    16201 cgaacgcggt ggagggcgtg gccgcgcaat cgcccttctt ccgaaccgag ttgacagaac
    16261 ccttgccaca tagtctattt ggactgatag ttttcgacta tgccgcgccg tgcgcttgag
    16321 aacccgatcg ccctggccgt cctcggcctt ctgctggaga gcagttccca cccgcaccag
    16381 atcctcgccg aactgcggaa acgcagcgac aaccaggccg ccgtcctcag cagggggacg
    16441 ctttaccaca ccgtcgctgc cctcgccggt gccggatggg tggcctcgca ggggcagcag
    16501 cgttcgggca accgcccgga gaagacggtc tacgcgctca ccctcgccgg ccgcgaggag
    16561 ttggtccggc gtctcgacgc gcagatacgc accccgcagc gggagttctc gcggttcctc
    16621 ggtgccgtca cctacctcgg agccctcggc aaggacggcg cgctcgaggc cctcgacgag
    16681 cgcgcccgcc gcctgcggga gcgcaccgcc gccgacgaga cgcgcctggc cgaagcccac
    16741 gcggctggtg taccgcgcct ccacgtcatc gaggccgagt acgcactcca cctggcacgc
    16801 gccgagacgg agtggatcga caccgtcacc gacgacatcc gcagcggagc cctggcatgg
    16861 ccaccgcaca ggaaggggcc gcagcgatga cccgcaggac cggcctgctc ttcggcatct
    16921 acccgggagg cgtggccggc gacgactccg gctccctcgc cgcgggaccg cccgacgagc
    16981 ccgccccggc ggccgccgct ctcgaccgtc tccaggggcg ccccggccgt cccttcctcg
    17041 tccgcgccta cacgggcttc gacgacacga cccggctcgg cgggccgcac gccaccgagg
    17101 caccggccga cgcggcccgg tacgccgtcc gcgggcgccg cctggacctg gtggcgcagt
    17161 accgctccgg ttctgcggac gtcgaaggct actgcgcctt cctccgcgaa ctcgtcgagc
    17221 agtacggcgc gttcaccgaa acactccagg tcgccgagga gccgaacgtc actgacaacc
    17281 ccgtgctcga cgggtactac ccggcagtcc gcgaggcgat cgtctgcggt gtccccgtgg
    17341 cgaaggcacg cgcacgcgaa ctcggccacc accacctgcg ggtggggtgc aacagcacgc
    17401 cgctcttcgg cccggccgcc ggcttcttca ccgacctcgc cgccgccggc ggtgcggact
    17461 tccccgccca actcgattac gtgggactgg acttcttccc cgacgtcttc cgcccggtcg
    17521 ccccctccga actcgccgcc acagtaagcg ggttgctgcg ccaccaccgc gagacggtgc
    17581 tcgccccggc aggtctggga cacctcccac tccacgtcac cgaacacggc tggcccacgg
    17641 gcccggaacg atccgccgcc cgtcaggccg aggtcgtcga gaccgtcgtc gatgtcctgg
    17701 cggcgcacgc ggcccccctc ggcgtgagtg gctacaccca cttcgcgctg cgcgacgccg
    17761 acagcacgcg gtccgggctc ttccaccgct tcgggctcac caccgacgac tacacgccca
    17821 agccggcgtt cgagacactg cgcgcactcg tcgagcggta cagcgtctga cggcggcgcc
    17881 catgcgggct gttgggcgct caacgactcc tcatccagag ccagttggcg gagcccccgc
    17941 aaccgacgtc accgccacat gcctcgaccg gtacacaacc cgagcggcaa gccggcacgc
    18001 cgcctcgggg ccggacgccg agcgggctca tccgcccgtg cctgtgcccg tgcccgagcg
    18061 agcccccaga tcagctcgac ccccgcacga tcagccgcgc ctccgtcacc accggcgccg
    18121 gaggggcatc gccgggccgc aagtcgagcc tgcgcagcag cagttcggcc atcatgctgc
    18181 ccattccctc gacgtcctgt cgtacggtcg tcagcgtcgg ctccgaccag gcggcgggct
    18241 ccaggtcgtc gtagccgacc accgcgacgt cctcgggtac gcgcaggccg cgccggtgga
    18301 gggtgcgcag ggcgcccgac gccatcaggt cggagccggc gaagaccgcg tcgatctccg
    18361 ggtccgtttc gaggagttcg gccatggcgg tctccccgcc ctccgccgtg aaggcgccgt
    18421 gtgcgaccag gggactcggc tgccggggtg cgccgtcggg ctcggcgagc gcgtcgtggt
    18481 agccgtcgag ccggtcctgc gcggaggtct ggtcgagcgg tccggtgatc acggc
//
