LOCUS       NZ_KB905425            26764 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Sciscionella marina DSM 45152 A37UDRAFT_scaffold_5.6, whole genome
            shotgun sequence.
ACCESSION   NZ_KB905425
VERSION     NZ_KB905425.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Sciscionella marina DSM 45152
  ORGANISM  Sciscionella marina DSM 45152
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Sciscionella.
REFERENCE   1  (bases 1 to 453413)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Sciscionella marina DSM 45152
            collection_date                   :: SEP 2006
            lat_lon                           :: Missing
            depth                             :: 516 m
            alt_elev                          :: Missing
            country                           :: China
            num_replicons                     :: Missing
            ref_biomaterial                   :: DSM 45152
            biotic_relationship               :: Free living
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: 19196758
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Sand; Sediment; Marine; Aquatic
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi11892
            Current Finishing Status          :: Level 2: High-Quality Draft
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2012
            Isolation Site :: Marine sand sediment at a depth of about 500 m,
            the northern South China Sea
            Cell Shape                        :: Rod-shaped
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28 C
            pH                                :: 7
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000379465.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 01:37:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,209
            CDSs (total)                      :: 8,146
            Genes (coding)                    :: 7,961
            CDSs (with protein)               :: 7,961
            Genes (RNA)                       :: 63
            rRNAs                             :: 4, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 185
            CDSs (without protein)            :: 185
            Pseudo Genes (ambiguous residues) :: 1 of 185
            Pseudo Genes (frameshifted)       :: 52 of 185
            Pseudo Genes (incomplete)         :: 155 of 185
            Pseudo Genes (internal stop)      :: 15 of 185
            Pseudo Genes (multiple problems)  :: 34 of 185
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:59:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 426649
            Orig. end                         :: 453413
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB905425.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405877
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Nikos  Kyrpides (nckyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-PGF and JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26764
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..26764
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26764
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:>26764](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>26764
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     misc_feature    complement(131..146)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.83"
                     /tool="antismash"
     misc_feature    complement(428..442)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    773..788
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
     misc_feature    complement(1014..1032)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.99"
                     /tool="antismash"
     misc_feature    complement(1130..1144)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.23"
                     /tool="antismash"
     misc_feature    complement(1137..1150)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.05"
                     /tool="antismash"
     gene            1177..2469
                     /locus_tag="A37U_RS0135295"
     CDS             1177..2469
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417345.1"
                     /locus_tag="A37U_RS0135295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_040589628.1"
                     /transl_table=11
                     /translation="MRENAEGESGARQTWLGRQGIVRPLAWGFLAVLLFMVGDGVELGF
                     LAPYLESIGFAATDVATLVSVYGIVVAVAAWLAGALAEAWGPRRVMLAGFLIWFVFELL
                     FLGIGVATKNYPVMLISYGIRGLGYPFFSYGFLVWVTMRTPKEVIGRAVGWYWFASTAG
                     LGVVSSYFAGIVIPWLGQLATMWLSLVFIAAGGVLLIVAVRARSERSDAGLSANLRKVA
                     GGLTVVKDHPRVGVGGVVRIINTLCFYAFPVFISTHMINEIGFTLSQWQTIWGTMLFAN
                     IIGNVAAGYLGDRIGQITVVAWFGGLLCVISVLAWYYVPEWLGANFAAAMAVSILLGLA
                     MAAYVPLSAIVPLLAPNNKAAAVAILNLGAGLSNAVGPVLARIFLGPLGVGGLMWLLAG
                     LYAVGIPLTYVLRDKGAEQSSGAGRAEVIPG"
     misc_feature    complement(2532..2545)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.5"
                     /tool="antismash"
     gene            2550..3497
                     /locus_tag="A37U_RS0135300"
     CDS             2550..3497
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016114.4"
                     /locus_tag="A37U_RS0135300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar-binding domain-containing protein"
                     /protein_id="WP_020501383.1"
                     /transl_table=11
                     /translation="METREPLGRVARLHYQHGMTHQEIGELLGFSRVKVTRMLAEARRA
                     GIVEIHIHGEATPFGELEAELTGAFGLAGAWIAPSFSDPERSLASVGMAGAECLTALAP
                     TVRTVAVGLSSSVAAIVAHLRPQEQLPELGFVPLAGSWGGASRGMSPHELVIGFGAAFG
                     ARTYHLPAPILAKTADAATAFAADPGVRQTLRLAAGAELLIAGVGAVEAGSGMLADTLT
                     ERERGQLTKRGAVGDISARFFDSVGSAVESTVDERVVGMSLRALARIPRRVAVGFGDQK
                     ITALRAALRTGLMNHLVTDVDTARTLLRTTRKGN"
     gene            3500..4132
                     /locus_tag="A37U_RS0135305"
     CDS             3500..4132
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012804.4"
                     /locus_tag="A37U_RS0135305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II aldolase/adducin family protein"
                     /protein_id="WP_020501384.1"
                     /transl_table=11
                     /translation="MRDAATTDELIERLAEAGELAVRRGLVLASGGNLSARLPGAEEFV
                     VTGAGTWLDRLTPEDFTVLNLDGEVVGGNPSPSSEWKLHQRTYRVREDVNAVVHIHPQH
                     AVLVDALGHPVRLFTLDHAAYVGSVGRTDYYPNGSDELADTAAAEAKQHNCVILGNHGC
                     SALGDSVGMAFRRAMNLEEAATATYRALCLGDTTTAFPEAALRTLHA"
     gene            4147..5103
                     /locus_tag="A37U_RS46905"
     CDS             4147..5103
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012515.4"
                     /locus_tag="A37U_RS46905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar kinase"
                     /protein_id="WP_020501385.1"
                     /transl_table=11
                     /translation="MRTDVVTLGLHILDILGRPVTRIPPGQEVELIEQITMTVAGTAAA
                     TAVDLARLGVRTASVGAIGRDALGAFLRERMTMEGVDCTGLSEVDTAQTSATILPIRPD
                     GGRPPLHVIGASAALTEDRIPWSLLAEARVLHFGGSGLLPALDGEPSVRILQRAKEIGL
                     TVLMDFIPTKDPQFPGQLAACLPYVDYLLPNLEDACFVAGTDDRASAIDWCHRRGVGAT
                     VLTMGADGVSIAERGGAERLLPAYAVDVVDTTGCGDAFSAGFITALLDGADLEQAAELG
                     LAAGSLVATGLGSDAGITDRFGLDQFATTTTRKQTGA"
     gene            5106..5870
                     /locus_tag="A37U_RS0135315"
     CDS             5106..5870
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (10-170). E-value: 2.5e-08.
                     Score: 26.0. Matches aSDomain:
                     nrpspksdomains_A37U_RS0135315_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495390.1"
                     /locus_tag="A37U_RS0135315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_040589472.1"
                     /sec_met_domain="adh_short (E-value: 6.4e-33, bitscore:
                     109.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSFSLQGKTAFVTGAARGIGAAIANGWARAGAAVACFDLDADS
                     AAEQAATLRGLGAEAIGIGGDVTDADSVAAAVRRTVDELGGLDIALNNAGIAHQAPAEE
                     LEPADWRRMIDVNLTGVFLCAQAQARVMLERGGGSIVNLASMSGSIVNRGLTQAHYNSA
                     KAGVMHLTKSLAVEWAGRGIRVNSISPGYTLTPMTQRPEVAGARAEWEDQTPMGRMVDM
                     AELVGPAIFLASRASSACTGLDLVADCGFVCW"
     aSDomain        5136..5615
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A37U_RS0135315_PKS_KR.1"
                     /evalue="2.50E-08"
                     /label="A37U_RS0135315_PKS_KR.1"
                     /locus_tag="A37U_RS0135315"
                     /protein_end="170"
                     /protein_start="10"
                     /score="26.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAFVTGAARGIGAAIANGWARAGAAVACFDLDADSAAEQAATLRG
                     LGAEAIGIGGDVTDADSVAAAVRRTVDELGGLDIALNNAGIAHQAPAEELEPADWRRMI
                     DVNLTGVFLCAQAQARVMLERGGGSIVNLASMSGSIVNRGLTQAHYNSAKAGVMHL"
     CDS_motif       5145..5210
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS0135315_0001"
                     /evalue="1.80E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="A37U_RS0135315"
                     /protein_end="35"
                     /protein_start="13"
                     /score="7.7"
                     /tool="antismash"
                     /translation="VTGAARGIGAAIANGWARAGAA"
     gene            complement(6256..7350)
                     /locus_tag="A37U_RS0135320"
     CDS             complement(6256..7350)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018684860.1"
                     /locus_tag="A37U_RS0135320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="WP_205623094.1"
                     /sec_met_domain="PALP (E-value: 9.3e-47, bitscore: 154.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRWNRAERDWVIGAIGTVTADANRSADTHLLTVPLPHQWGIQLY
                     LKDESTHPTGSLKHRLARSLFLYALCNGWITEGSAIVEASSGSTAVSEAYFARLLGLPF
                     IAVMPATTSAAKIAMIEREGGTCHLVTDPVTIYQESARLADELGGHFMDQFTYAERATD
                     WRGNNNIAESIFDQLAYEPFPIPEWIVTGAGTGGTSATIGRFLRYHRRHTRLCVVDPEN
                     SAFFPGWKHRDSAIRTGHASRIEGIGRPRFEPSFIPTVVDRMIQVPDAASVAAVRFLRS
                     ITGLTAGASTGTSLFAAYRLICEMRAENTRGSIVALLCDPGDRYTDTYYSDSWAAHQGF
                     DLESYLDILHTAHTTGKWLGPPSR"
     gene            complement(7384..7887)
                     /locus_tag="A37U_RS0135325"
     CDS             complement(7384..7887)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005466697.1"
                     /locus_tag="A37U_RS0135325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RidA family protein"
                     /protein_id="WP_020501388.1"
                     /transl_table=11
                     /translation="MTGNHSRAMASAPARPSEQLTSLGLALPPIAAPSGFYAAAVRHAD
                     LIYTSGQLPVRAGLLAATGLVGAAITVDEASKLAELCTLNALAAAADLAGGIDRLDRIV
                     KVAGFVASAEGFIEHALVINGASDLLLRVFGDRGRHARSALGVKSLPLGAPVEVELIIA
                     SEED"
     gene            complement(7884..8288)
                     /locus_tag="A37U_RS0135330"
     CDS             complement(7884..8288)
                     /EC_number="1.11.1.-"
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014608.4"
                     /locus_tag="A37U_RS0135330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="OsmC family protein"
                     /protein_id="WP_020501389.1"
                     /transl_table=11
                     /translation="MSDYPVTVRHTRDLSFTIDNGRTEARVEWDAVDSTWQATELFLTG
                     LGACMLATMMDYAQSNNIDATGAHVELSGDTATRPMRLSTLHITYVLPDTLSQNQIEAL
                     VRAGNRCKVHNTIENHPEFTVTTRKATVSR"
     gene            complement(8319..9410)
                     /locus_tag="A37U_RS0135335"
     CDS             complement(8319..9410)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660235.1"
                     /locus_tag="A37U_RS0135335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF917 domain-containing protein"
                     /protein_id="WP_020501390.1"
                     /transl_table=11
                     /translation="MNHIDANAIADIARGAAVLGAGGGGDPHLGALMAERAITDSGPVR
                     TVGLPDLPEDAVVLPVAIMGAPTVIVEKPPAGGEFAQAVRAVQTAYGSTITHIACFEAG
                     GLNSMMPLVCAAETNLPLIDGDGMGRAFPELQMVLATLDGISTTPMAMVDDKGNTVLLD
                     TVDNAWAEQLARSATVEMGCGACIALYPMTGREARKALVPDTVSLAGRLGRLLRATRGD
                     HRDPVEALITETDGVILFHGRVTDVRRRTKAGFARGQAEIQGTGPDTGASMTLHFQNEH
                     LLATRDGAVVASVPDLICVLEADTGEPITTEAMRYGFRVTVIGLPCHPRWRSPAGLALV
                     GPSYFGYEHEYVPLDRLNTASIA"
     gene            complement(9407..10966)
                     /locus_tag="A37U_RS0135340"
     CDS             complement(9407..10966)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660236.1"
                     /locus_tag="A37U_RS0135340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="WP_020501391.1"
                     /transl_table=11
                     /translation="MHIGIDVGGTNTDAVLIHHGVVAASVKRPTTLDVTTGIVEAITGL
                     SENVTFDLTGISAVAIGTTHFTNAVVQARGLAPTATIRLGLPASASVPPLTAWPARLRA
                     AVGEHVFLCHGGHEFDGRQISELDRGELCRVAETIGERGITSAAISSIFSPVNRDDELA
                     AAEVLVSQVPGLRISLSHEIGRIGLLERENATIINASLLPVADRTTEAFAVALTRAGID
                     APLYLSQNDGTLMDIDYVRRYPVATFAAGPTNSMRGAAMLSGLNDCIVVDVGGTTADIG
                     AVVNGFPRPATTAVDIAGVRTNFRMPDVVSIGIGGGSIVDDSDPSRITVGPESVGYELH
                     AKSRVFGGDTLTATDIAVAGGLYTVGDPALIADLPGNQVRDTLDHIAARVAEHADTMRT
                     STEAVPIVLVGGGSILLPDNLPGFDKVVRPEEFTVANAIGAAIAQVGGEVDRVYSDTGR
                     GRDAILEDAKREAAEKAILAGAAPDSVRTVEVDELPMAYLPGDAVRVRVKAVGELILED
                     TP"
     gene            complement(10969..12345)
                     /locus_tag="A37U_RS0135345"
     CDS             complement(10969..12345)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660237.1"
                     /locus_tag="A37U_RS0135345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytosine permease"
                     /protein_id="WP_040589475.1"
                     /transl_table=11
                     /translation="MSRSRSDDTVVVGHDDYALERVPADARYPWWSIAIQRFGQLSALA
                     QFLLGATLGFGMPFWNAILAITVGSVLLEIVTVFVGIAGMREGLSTSVLARWTGFGTKG
                     SALVGLLIGVSLIGWFGVQNAVFGTGLHSVLGAMPVWVWSLLGGVAVTAVVVYGFGGMT
                     WTAYVTVPAFLVLAIWAVARELSRHPIADLLASAPAGPRLSLAAGATLVAGGFIVGAVM
                     TPDMTRYNRSVADVVKQTVIGVTLGEYVVGVIGVLLAHAARTSDVVMMITTTSGLIGTV
                     VLVASILKINDWNLYSSSLGLVNVLHVLLGRKVNRAVVTIVVGVLGAALSALGILAYFT
                     DFLSFVGILMPPVAGICIAEYFIVKTWRPVLEASRGRGELPATAPGWVPAGLVAWLTGG
                     LVGYFVDIGIPAINSLAVATVAYIVLGKLGLIARRGATASQSESVSATSTAIAHNTDQG
                     "
     misc_feature    complement(12443..12461)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.3"
                     /tool="antismash"
     gene            12494..13570
                     /locus_tag="A37U_RS46910"
     CDS             12494..13570
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044937.1"
                     /locus_tag="A37U_RS46910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF917 domain-containing protein"
                     /protein_id="WP_020501393.1"
                     /transl_table=11
                     /translation="MRLEDDQVSALATGCALLGSGGGGATDVAEVLLRGALAGAPVELG
                     AADRLAEDAVVATVGAVGSSTAMLERIPSAEEFVRAARATEARLGRPLAAVQSLEIGGV
                     NGLLGACVAAWLGLPLLDADAMGRAYPRLNLTTLAGHVPLTPLALSAPRGEVIVIDTAD
                     ERSVESLVRAMLPSLGSWAAMCLHPATAAQYRRASVQFSLSRALDLGHHWQQRQRGLLT
                     TAELFDRTGARHLYEGTVAEVIRTQPEIGGVATIHDGGSGSAIMRLDFANEYILAFEDG
                     YPVSSVPEIIVVLDQRTWKPISVEQLAVQQRVRVLALPAPPELFNGRHDAENRFGLRAY
                     GREPVHPQGAPDATADLR"
     gene            13548..15122
                     /locus_tag="A37U_RS0135355"
     CDS             13548..15122
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037653.4"
                     /locus_tag="A37U_RS0135355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_157183204.1"
                     /transl_table=11
                     /translation="MQLLTFDDLRALEVLEHSTVVGDSSPHHGIAAVEVLESHEVLDKP
                     LAPRSAVLVCLDESLDRHRQHLLDLLLRRAHQARAGAIIVLGSTGEIPAATRSLATKLA
                     IPVLLAPAGSSPLTTAVELRSAVLEPELAMSNCLLSVTRQLSSGPRNPQELCHLVGKPI
                     RANVGICTAQGVFIAGGPLETPVTQLIGGHIPESFHHGDRSIAVTPIIGSGQLPVLWSI
                     AERAGGGPFWRELALHALALARGEITAWLAREQLSTERDARVRTTLLTEIVEHGNAIPE
                     SIEQQAVSVGWQLLGWHTGVHLTFSASTPMSTLAIETLNTDLAKPPLSLGPLVERANGW
                     SAWTTTQDQPGPEHARTLARELESRLRQLTAHYPGLTCAAGVGAAQRDISGIATTLSQA
                     RQAASVASADRSPITVRAVQDLGASRLLLGWYASGAFHDYARQLLAPLLEAAEPELRTT
                     LETYLDRACSAMHTSRVLGIHRNTVSLRISRIETLLGASLTDADTRLTLQLALRALRAG
                     SAADTER"
     gene            complement(15788..16579)
                     /locus_tag="A37U_RS0135360"
     CDS             complement(15788..16579)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441093.1"
                     /locus_tag="A37U_RS0135360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_020501395.1"
                     /transl_table=11
                     /translation="MKIACWQAVATDGAESTALDRLAAVARKAAASGAQLLVTPELSGT
                     GYLTDATRLRSLAEPADGPICARFSAIAAETGIAIAHGWPEADGERVYNAARLVGADGA
                     TLLRYRKSHLYGSVERAAFDPGDDGVRQAELAGLTLGILICYDVEFPEAVRAHALAGTQ
                     LLVVPTALMQPCQFVATGLVPARAFENQLFIAYANWSGTGQGLTYCGLSRIAGPDGAVL
                     NEKNGPGGEGELRLAELDLTAIAKARELSPYLADRRPELFG"
     gene            16673..17377
                     /locus_tag="A37U_RS0135365"
     CDS             16673..17377
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020643877.1"
                     /locus_tag="A37U_RS0135365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_020501396.1"
                     /transl_table=11
                     /translation="MGIPQRIKVIVVDDQQIVREGLVALMGLLEDIEVVGSAPNGALAI
                     ELVDRLDDLDVVLMDLNMPVMSGTEATKRIMRDHPDVAVVVLTTYSDDQTIADALAAGA
                     RGYLTKEAGRKQIGSALRSVVAGQMTFGADVSRQVVNVLFESGGQGSPVPTGAKPAEHK
                     TGPPDGLTAREAEVLGLIAAGLSNATIAAELFIGEATVKTHINNAFAKIGVRNRAEAVR
                     YAVRNGLEKEPG"
     gene            complement(17378..18283)
                     /locus_tag="A37U_RS0135370"
     CDS             complement(17378..18283)
                     /NRPS_PKS="Domain: PKS_AT (52-247). E-value: 1.8e-11.
                     Score: 35.9. Matches aSDomain:
                     nrpspksdomains_A37U_RS0135370_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF044982.1"
                     /locus_tag="A37U_RS0135370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ACP S-malonyltransferase"
                     /protein_id="WP_020501397.1"
                     /transl_table=11
                     /translation="MSPTALVFPGMAPNRFAELTKFLLLNRAARQRVTEADDAIGYSVL
                     DAYADSTDDYGTAAQLAFLVSCVAIADELELRPDVLTGVSFGQKAAAVFSGALDFSDAV
                     RLTAIQAACEQEYFAVQHQDVVTHTVMRVPEDGWRTVLGELSWYEISGVLDEGFHMISL
                     HSGELDGFITRISEVGGYSLYTMRPPVHAPSFTALRNTAERSAFGDCPLRDPEIPVLAD
                     QDGSLVRTAEGIRGMLLDTFDRPIDWPQVTAALHRLEITDLHFCGTDNLFSRVPRTKEF
                     RVRSNNPKLALRPRKETVVA"
     aSDomain        complement(17543..18127)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A37U_RS0135370_PKS_AT.1"
                     /evalue="1.80E-11"
                     /label="A37U_RS0135370_PKS_AT.1"
                     /locus_tag="A37U_RS0135370"
                     /protein_end="247"
                     /protein_start="52"
                     /score="35.9"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: CHC-CoA"
                     /tool="antismash"
                     /translation="DDYGTAAQLAFLVSCVAIADELELRPDVLTGVSFGQKAAAVFSGA
                     LDFSDAVRLTAIQAACEQEYFAVQHQDVVTHTVMRVPEDGWRTVLGELSWYEISGVLDE
                     GFHMISLHSGELDGFITRISEVGGYSLYTMRPPVHAPSFTALRNTAERSAFGDCPLRDP
                     EIPVLADQDGSLVRTAEGIRGMLLDTFDRPID"
     CDS_motif       complement(17957..18055)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS0135370_0001"
                     /evalue="3.00E-06"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="A37U_RS0135370"
                     /protein_end="109"
                     /protein_start="76"
                     /score="20.0"
                     /tool="antismash"
                     /translation="RPDVLTGVSFGQKAAAVFSGALDFSDAVRLTAI"
     gene            complement(18280..19677)
                     /locus_tag="A37U_RS0135375"
     CDS             complement(18280..19677)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (5-365). E-value: 6.8e-57.
                     Score: 184.8. Matches aSDomain:
                     nrpspksdomains_A37U_RS0135375_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016333305.1"
                     /locus_tag="A37U_RS0135375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_338055146.1"
                     /sec_met_domain="AMP-binding (E-value: 7.2e-54, bitscore:
                     177.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSVQTLDEFELRTLGVADALSARGLSPGDRVMLKAGNSVGYVSA
                     LFALMHLGASIVLVDPQETANQTGEIIERAGVRMSIVDDDAPLTQDQSPVYVYELLADA
                     ASAPPGRRLCFDRWCALPDSIIMWSSGSTGAPKGIVKNGARFLKNMQRNADQVGHRADD
                     VLLPLLPFSHQYGISMVMIAWLTRCSLIIAPYRRLDHALRMAGQCGATVVDAAPSTYQS
                     MLNIVGKRPEARAALMKTRMLCSGAAPLDSPLVAEYESEFGMTLLDSYGSTELGNLAFA
                     TLENPVGTGQVMDGIGCRIVDENDRDLAATEIGEVLIDCPDMLTGLLGEDAMVTPAEQG
                     WHRTGDLGYLDENRNLFILGRKSAVHRMGYTIHPEVIERKVAAQGCTARIISLPEKRQG
                     VQLVFFVADPQRRESGYWRSVLTEALPPHEQPNRVVVVDRFPVNRNGKPDKNRMEELAR
                     AESGVAA"
     aSDomain        complement(18583..19662)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A37U_RS0135375_AMP-binding.1"
                     /evalue="6.80E-57"
                     /label="A37U_RS0135375_AMP-binding.1"
                     /locus_tag="A37U_RS0135375"
                     /protein_end="365"
                     /protein_start="5"
                     /score="184.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="TLDEFELRTLGVADALSARGLSPGDRVMLKAGNSVGYVSALFALM
                     HLGASIVLVDPQETANQTGEIIERAGVRMSIVDDDAPLTQDQSPVYVYELLADAASAPP
                     GRRLCFDRWCALPDSIIMWSSGSTGAPKGIVKNGARFLKNMQRNADQVGHRADDVLLPL
                     LPFSHQYGISMVMIAWLTRCSLIIAPYRRLDHALRMAGQCGATVVDAAPSTYQSMLNIV
                     GKRPEARAALMKTRMLCSGAAPLDSPLVAEYESEFGMTLLDSYGSTELGNLAFATLENP
                     VGTGQVMDGIGCRIVDENDRDLAATEIGEVLIDCPDMLTGLLGEDAMVTPAEQGWHRTG
                     DLGYLDENRNLFILGRKSAV"
     CDS_motif       complement(19258..19302)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS0135375_0001"
                     /evalue="3.90E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="A37U_RS0135375"
                     /protein_end="140"
                     /protein_start="125"
                     /score="13.4"
                     /tool="antismash"
                     /translation="IMWSSGSTGAPKGIV"
     misc_feature    complement(19970..19984)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.65"
                     /tool="antismash"
     misc_feature    19971..19982
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.05"
                     /tool="antismash"
     misc_feature    complement(19993..20008)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.56"
                     /tool="antismash"
     misc_feature    complement(19994..20003)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.36"
                     /tool="antismash"
     gene            20001..>26764
                     /locus_tag="A37U_RS53245"
     CDS             20001..>26764
                     /NRPS_PKS="Domain: PKS_PP (11-93). E-value: 2.3e-22. Score:
                     71.1. Matches aSDomain:
                     nrpspksdomains_A37U_RS53245_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (113-538). E-value:
                     1.6e-180. Score: 592.5. Matches aSDomain:
                     nrpspksdomains_A37U_RS53245_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_DH (895-1053). E-value: 8e-50.
                     Score: 161.4. Matches aSDomain:
                     nrpspksdomains_A37U_RS53245_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1348-1523). E-value: 1.8e-60.
                     Score: 196.0. Matches aSDomain:
                     nrpspksdomains_A37U_RS53245_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (1621-1692). E-value: 3.6e-33.
                     Score: 105.7. Matches aSDomain:
                     nrpspksdomains_A37U_RS53245_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1712-2137). E-value:
                     1.9e-174. Score: 572.5. Matches aSDomain:
                     nrpspksdomains_A37U_RS53245_PKS_KS.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029778.1"
                     /locus_tag="A37U_RS53245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_020501399.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 5.2e-95, bitscore:
                     312.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.6e-22, bitscore: 75.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 9.1e-59, bitscore:
                     193.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.1e-15, bitscore:
                     51.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 1.4e-218, bitscore:
                     720.8, seeds: 217, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNPIQDIGGLSDYDRSRVLGEFVRAHLAAVLEDWPAAGVDEHRS
                     FLELGLDSVAAVALHARLTEATGLELPVTLAFDHPNTASLAVYLRGRLLGESTEEPSVT
                     PVAAAEGEPIAIVGMSTRFPGGVASPEQFWELLAEGRDATSEFPTDRGWDLAALYDADP
                     DRPGTTYTRRGGFLHDAAEFDAAFFGINPREALAMDPQQRLLLESGWHALEDAGIDPAE
                     LRGSRTGVYVGAEAQDYGPRLEEAEGAEGYLDIGTAGSVASGRIAYTLGLEGPAVTVDT
                     ACSSSLVALHLAVQALRRGECALALAAGVAVMSSPGGFLSFSRQRALSADGRCRAFAAD
                     ADGTGWGEGAGTVVLAPLSEARRRGLRVLALVSGIAVNSDGASNGLTAPSGPAQQRVIE
                     QALADAGIPAAEVDAVEAHGTATLLGDPIEANALQAVYGSGRPAEQPLLLGSVKSNIGH
                     TQAAAGLAGVIKMVLAMRAGTLPATLHVETPTPHVNWADRGVALLTEACPWPATDHPRR
                     GGVSSFGMSGTNAHVILESAPVEAASEEPVTFPAPWPLPVTAHTAAALRAQAAALVEYV
                     DRYPLADLGAALGTTRAALRHRAVVLAEDPESARAQLRALAAGEDAPGVIRGRGTEGGL
                     AVLLRGELPRGACGALYRAYPVFATALSEACAELNLQLATPLLGALLAEAPELEQPEYA
                     DAAAFACDVALYRLFESWGGHADLVAGTGIGELAAAHVAGVLSLADACALAGTIARGAG
                     AAELRRLTRALSFDRPATSVLDIGTGEPVDAGTLADAGHWAGLGARNTVPCPAWSERHQ
                     VRAVLELGGSPVATVAPTEAATVPEALAALFAQGLELDWRAVYSGRDVRDVCLPGYAFQ
                     RERFWLPGIGTAGSPREVGQSSAEHPLLGAVLAHAAKDELTLTGRLALAAHPWLGEHRV
                     RGAAILPGTALLELAVQAGGHVGARTVAELTLHAPLVLPESAGMTVQATVGEPDAEGNR
                     GFAVHARQEDIGPWTKHASGTLAVAPLPPGPEVPRPETVGVAADAVYAALAETGLDYGR
                     TFRGLHTAWRSGDEVIAELVLPDGAPDGFALHPVLSDAALHALELFDGAFGSDGRAWLP
                     FSFGGVTVHATGARRARVRMTKTGTDTVALTVAGHDGTPIATVESLSLRPVSAVADALY
                     RTGWVPLSRSRPDEPGASWAVLGAPVPELDAPAHPDLPALLLSELPEFVLAPVAPREAH
                     AAAGDVLDLLNAWLRVPRTADSRLVVLTTGALATDAADTVPGLDHAPVTGLVRAAQDEE
                     TGRILLVDTDDSAASRTVLAEAVSAAVAEGETELALREGRAFIPRLSTTDAHPSTVDVP
                     GLDPEGTVLITGGTGVLGGSLARHLVCEHGIRHLVLLGRSAREGELDAELAALGAEVSV
                     VACDVADKDALAAVLADIPENRPLTAVVHAAGTLDDGVLGSLTRTRLSTVLTPKVDAAL
                     HLHELTKDLPLAAFVLFSSSAALLGAAGQANYAAANTFLDALAQHRRAHGLPALSLQWG
                     LWEQASGLTARLGEADHARLRRSGLAPLPTERALAMFDAALRTGNSVVAPIILDHPAVR
                     AKVETDGGAPLLRGLAGAKPRIAAVAEDAPVAEQHGSPDQLIDLVREHVAAVLGHAAPH
                     AVEVDQAFTELGFDSLTAVELRNRLGTALDRRLPATLIFDYPNPAALARHLAEESGGGA
                     AVRTPATVVQDAGEPVAIVGMGARFPGGVAGPDDLWRLVAEGVDAIGEFPDDRGWDLDA
                     LYDPDPDVPGKMYVRNGGFLPDALDFDAEFFGISPREAVAMDPQQRQLMEVAWEALEHA
                     GIDPNSLKGSRTGVFAGIMYHDHAARLREIPEELEGFLGNGSAASVLTGRIAYTLGLEG
                     PAMSVDTACSSSLVSLHLAAQALRRGEATLALAGGVTVLSTPEVFVDFSRQRGLSPDGR
                     CRAFAEEADGTGWAEGVGMLVLERLSDAVSNGHEVLAVVRGSAVNSDGASNGLSAPNGP
                     SQQRVIEAALVDARLGAGDVDVVEAHGTGTALGDPIEVQALQAVYGKDREPGRPLWLGS
                     LKSNLGHAQAAAGVGGVIKLVQALRAGLLPRTLHASRPSAKIEWDGGGVELLQESRAWT
                     SDGPRRGAVSSFGISGTNAHVILEQAPESATEAETATGAGPVPVVVSGKTREALRGQAS
                     RLAECVRVHPEFSVADIGYSLATGRAEFAHRGVVVAGDRGELLAGLEGLAAGAESALTG
                     SGSVAASRVLMVFPGQGSQWVGMGLEL"
     aSDomain        20034..20279
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A37U_RS53245_PKS_PP.1"
                     /evalue="2.30E-22"
                     /label="A37U_RS53245_PKS_PP.1"
                     /locus_tag="A37U_RS53245"
                     /protein_end="93"
                     /protein_start="11"
                     /score="71.1"
                     /tool="antismash"
                     /translation="SDYDRSRVLGEFVRAHLAAVLEDWPAAGVDEHRSFLELGLDSVAA
                     VALHARLTEATGLELPVTLAFDHPNTASLAVYLRGRL"
     aSDomain        20340..21614
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A37U_RS53245_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.60E-180"
                     /label="A37U_RS53245_PKS_KS.1"
                     /locus_tag="A37U_RS53245"
                     /protein_end="538"
                     /protein_start="113"
                     /score="592.5"
                     /tool="antismash"
                     /translation="IAIVGMSTRFPGGVASPEQFWELLAEGRDATSEFPTDRGWDLAAL
                     YDADPDRPGTTYTRRGGFLHDAAEFDAAFFGINPREALAMDPQQRLLLESGWHALEDAG
                     IDPAELRGSRTGVYVGAEAQDYGPRLEEAEGAEGYLDIGTAGSVASGRIAYTLGLEGPA
                     VTVDTACSSSLVALHLAVQALRRGECALALAAGVAVMSSPGGFLSFSRQRALSADGRCR
                     AFAADADGTGWGEGAGTVVLAPLSEARRRGLRVLALVSGIAVNSDGASNGLTAPSGPAQ
                     QRVIEQALADAGIPAAEVDAVEAHGTATLLGDPIEANALQAVYGSGRPAEQPLLLGSVK
                     SNIGHTQAAAGLAGVIKMVLAMRAGTLPATLHVETPTPHVNWADRGVALLTEACPWPAT
                     DHPRRGGVSSFGMSGTNAHVILESAP"
     aSModule        20340..25076
                     /domains="nrpspksdomains_A37U_RS53245_PKS_KS.1"
                     /domains="nrpspksdomains_A37U_RS53245_PKS_DH.1"
                     /domains="nrpspksdomains_A37U_RS53245_PKS_KR.1"
                     /domains="nrpspksdomains_A37U_RS53245_ACP.1"
                     /incomplete
                     /locus_tags="A37U_RS53245"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       20595..20621
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0001"
                     /evalue="3.80E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="A37U_RS53245"
                     /protein_end="207"
                     /protein_start="198"
                     /score="7.2"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       20820..20867
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0002"
                     /evalue="1.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="A37U_RS53245"
                     /protein_end="289"
                     /protein_start="273"
                     /score="20.4"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       21243..21287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0003"
                     /evalue="9.50E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="A37U_RS53245"
                     /protein_end="429"
                     /protein_start="414"
                     /score="8.9"
                     /tool="antismash"
                     /translation="VEAHGTATLLGDPIE"
     CDS_motif       21348..21392
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0004"
                     /evalue="9.10E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="A37U_RS53245"
                     /protein_end="464"
                     /protein_start="449"
                     /score="11.7"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQAAAG"
     CDS_motif       22170..22235
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0005"
                     /evalue="6.00E-07"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="A37U_RS53245"
                     /protein_end="745"
                     /protein_start="723"
                     /score="21.4"
                     /tool="antismash"
                     /translation="IGELAAAHVAGVLSLADACALA"
     aSDomain        22686..23159
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A37U_RS53245_PKS_DH.1"
                     /evalue="8.00E-50"
                     /label="A37U_RS53245_PKS_DH.1"
                     /locus_tag="A37U_RS53245"
                     /protein_end="1053"
                     /protein_start="895"
                     /score="161.4"
                     /tool="antismash"
                     /translation="HPLLGAVLAHAAKDELTLTGRLALAAHPWLGEHRVRGAAILPGTA
                     LLELAVQAGGHVGARTVAELTLHAPLVLPESAGMTVQATVGEPDAEGNRGFAVHARQED
                     IGPWTKHASGTLAVAPLPPGPEVPRPETVGVAADAVYAALAETGLDYGRTFRGL"
     CDS_motif       22770..22847
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0006"
                     /evalue="2.60E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="A37U_RS53245"
                     /protein_end="949"
                     /protein_start="923"
                     /score="29.6"
                     /tool="antismash"
                     /translation="WLGEHRVRGAAILPGTALLELAVQAG"
     aSDomain        24045..24569
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A37U_RS53245_PKS_KR.1"
                     /evalue="1.80E-60"
                     /label="A37U_RS53245_PKS_KR.1"
                     /locus_tag="A37U_RS53245"
                     /protein_end="1523"
                     /protein_start="1348"
                     /score="196.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLITGGTGVLGGSLARHLVCEHGIRHLVLLGRSAREGELDAEL
                     AALGAEVSVVACDVADKDALAAVLADIPENRPLTAVVHAAGTLDDGVLGSLTRTRLSTV
                     LTPKVDAALHLHELTKDLPLAAFVLFSSSAALLGAAGQANYAAANTFLDALAQHRRAHG
                     LPALSLQWGLWE"
     CDS_motif       24048..24149
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0007"
                     /evalue="5.70E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="A37U_RS53245"
                     /protein_end="1383"
                     /protein_start="1349"
                     /score="31.8"
                     /tool="antismash"
                     /translation="TVLITGGTGVLGGSLARHLVCEHGIRHLVLLGRS"
     CDS_motif       24417..24524
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0008"
                     /evalue="1.50E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="A37U_RS53245"
                     /protein_end="1508"
                     /protein_start="1472"
                     /score="62.6"
                     /tool="antismash"
                     /translation="AAFVLFSSSAALLGAAGQANYAAANTFLDALAQHRR"
     aSDomain        24864..25076
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A37U_RS53245_ACP.1"
                     /evalue="3.60E-33"
                     /label="A37U_RS53245_ACP.1"
                     /locus_tag="A37U_RS53245"
                     /protein_end="1692"
                     /protein_start="1621"
                     /score="105.7"
                     /tool="antismash"
                     /translation="DLVREHVAAVLGHAAPHAVEVDQAFTELGFDSLTAVELRNRLGTA
                     LDRRLPATLIFDYPNPAALARHLAEE"
     aSDomain        25137..26411
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A37U_RS53245_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.90E-174"
                     /label="A37U_RS53245_PKS_KS.2"
                     /locus_tag="A37U_RS53245"
                     /protein_end="2137"
                     /protein_start="1712"
                     /score="572.5"
                     /tool="antismash"
                     /translation="VAIVGMGARFPGGVAGPDDLWRLVAEGVDAIGEFPDDRGWDLDAL
                     YDPDPDVPGKMYVRNGGFLPDALDFDAEFFGISPREAVAMDPQQRQLMEVAWEALEHAG
                     IDPNSLKGSRTGVFAGIMYHDHAARLREIPEELEGFLGNGSAASVLTGRIAYTLGLEGP
                     AMSVDTACSSSLVSLHLAAQALRRGEATLALAGGVTVLSTPEVFVDFSRQRGLSPDGRC
                     RAFAEEADGTGWAEGVGMLVLERLSDAVSNGHEVLAVVRGSAVNSDGASNGLSAPNGPS
                     QQRVIEAALVDARLGAGDVDVVEAHGTGTALGDPIEVQALQAVYGKDREPGRPLWLGSL
                     KSNLGHAQAAAGVGGVIKLVQALRAGLLPRTLHASRPSAKIEWDGGGVELLQESRAWTS
                     DGPRRGAVSSFGISGTNAHVILEQAP"
     CDS_motif       25392..25418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0009"
                     /evalue="3.40E-01"
                     /label="PKSI-KS_m2"
                     /locus_tag="A37U_RS53245"
                     /protein_end="1806"
                     /protein_start="1797"
                     /score="4.6"
                     /tool="antismash"
                     /translation="DPQQRQLME"
     CDS_motif       25620..25667
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0010"
                     /evalue="5.10E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="A37U_RS53245"
                     /protein_end="1889"
                     /protein_start="1873"
                     /score="18.5"
                     /tool="antismash"
                     /translation="GPAMSVDTACSSSLVS"
     CDS_motif       25668..25724
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0011"
                     /evalue="3.50E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="A37U_RS53245"
                     /protein_end="1908"
                     /protein_start="1889"
                     /score="-2.8"
                     /tool="antismash"
                     /translation="LHLAAQALRRGEATLALAG"
     CDS_motif       26043..26087
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0012"
                     /evalue="5.10E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="A37U_RS53245"
                     /protein_end="2029"
                     /protein_start="2014"
                     /score="12.3"
                     /tool="antismash"
                     /translation="VEAHGTGTALGDPIE"
     CDS_motif       26148..26192
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0013"
                     /evalue="1.20E-02"
                     /label="PKSI-KS_m6"
                     /locus_tag="A37U_RS53245"
                     /protein_end="2064"
                     /protein_start="2049"
                     /score="8.7"
                     /tool="antismash"
                     /translation="GSLKSNLGHAQAAAG"
     CDS_motif       26715..>26764
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS53245_0014"
                     /evalue="1.00E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="A37U_RS53245"
                     /protein_end="2255"
                     /protein_start="2238"
                     /score="23.9"
                     /tool="antismash"
                     /translation="MVFPGQGSQWVGMGLEL"
ORIGIN
        1 atagggcagg tagagcactc cgtccgcgcc cggtggtacc cgggcggctt cggcctccac
       61 agcggtccag ctccggtgcg tatcgccggt gacccctcgc gcccattcca ggttcggcgt
      121 tccggacatc gggcagaggc attcgagaat ccggccgtgg tggccggtgg cgagcaggat
      181 gctcgccggt gcggtgacct cctcggcgct gctgcgcacc gtgccgagga acgcggtggt
      241 gcccatgatc gcgtagctct cgcccggttc gaccgcgccg aggccgatgc ccgcggcggc
      301 cgtgtccacc atgccggtgg ccaccggtgt cccggggcgc agcccgaggg catgggccgc
      361 gtcgtggcgc agcggccggg tcgtggtcga cgggacgacc ggtggcagta gtccggcgaa
      421 tcgccgatgg ccgagccggt cgagtagctg ctgggagtac tgcccggtgc gtacgtcgag
      481 gtaggtgcgc gaggcttcgg aggcgtccgt ttcgagtacg ccggtcagcc ggagccggat
      541 ccagtctttg cagttcgcct ggtgccgtgc ctcgggccgc aggtgttcga gcaggaccgg
      601 cagggccccg gcgaacaatg tggagccggt gacggcgtgg accgcggcgg cgcggccatc
      661 tcgttcccat tcgtcgacaa cggtggtcgc gcgcccgtcc agccacagtt tcgccggtcc
      721 gatcgggcgg tgttcggcgt ccagcagcca ggcgccgtcg ccctgcccgg tgacgccgat
      781 cgcgctcacc tcgacctcgc ccgccgcgtg cagtgcggcc gtgacggtgt gctgcacgga
      841 ctgccagatt gtcgccatgg actgctcggc acagtccggc cgtggtcgcc cgacctcgag
      901 gggaactcgc gctgtcgcga ggttccggcc atccggcgtg atgatcaccg tcttgaccgc
      961 ggtcgtacct gcgtcgatcc cgacgatggc ggaaatggcc atcacatctc tccactgaac
     1021 atatgtgcac tacatcgtgc agttgttcgg aatctagaac gccggacctc gttcggtcaa
     1081 ctcttgacat tcgcgccggt cgagctgatg ctctatcgat ccaaagtgca atcgtctgaa
     1141 caattgttcg tagcgcgggc tcgaagagga gtgctgatgc gcgaaaacgc cgagggggaa
     1201 agcggcgccc ggcagacgtg gctgggccgt caggggatcg tccgtccgct cgcctggggt
     1261 ttcctcgcgg tgctgctgtt catggtcgga gacggtgtgg agctcggatt cttggctcca
     1321 tacctggaat ccatcggttt cgcggccacc gatgtcgcga ccctggtcag cgtttacggc
     1381 atcgtggtcg cggtggccgc gtggctggcc ggtgcgctcg ccgaggcgtg gggaccgcgg
     1441 cgggtcatgc tggccgggtt cctgatctgg ttcgtgttcg agctgctgtt cctcgggatc
     1501 ggtgtggcga ccaagaacta tccggtgatg ctgatctcgt atgggatccg cggcctcggg
     1561 tacccgttct tctcctacgg tttccttgtc tgggtgacca tgcgtacccc gaaggaggtg
     1621 atcggcaggg cggtcggctg gtactggttc gcttccacgg ccgggctcgg cgtggtcagc
     1681 tcctacttcg cggggatcgt catcccatgg ctcggccagc tggcgacgat gtggctctcg
     1741 ctggtgttca tcgccgcggg tggggttctg ctgatcgtcg cggtgcgggc gcgctccgag
     1801 cgcagcgatg ccggactctc ggcgaacctg cggaaggtgg caggcgggct gaccgtggtg
     1861 aaagaccatc cacgcgtcgg agtcggcggg gtggtacgca tcatcaacac actgtgcttc
     1921 tacgcgtttc cggtcttcat ctccacgcac atgatcaacg agatcgggtt cacgctctcg
     1981 cagtggcaga ccatctgggg cacgatgttg ttcgccaaca tcatcggcaa tgtggcggcc
     2041 gggtatcttg gcgaccggat cggccagatc accgtggtcg cctggttcgg cgggctgctc
     2101 tgcgtgatct cggtgctggc ctggtactac gtgccggaat ggctcggcgc gaacttcgcg
     2161 gccgcgatgg cggtgtccat cctgctcggg ctggcgatgg ccgcttatgt gccgttgagc
     2221 gcgatcgtgc cgctgctcgc gccgaacaac aaggcggctg cggtggcgat cctcaacctc
     2281 ggagccgggc tgagcaacgc ggtcggaccg gtactggccc ggatcttcct cggcccgctc
     2341 ggagtcggtg ggctgatgtg gctgctggcc ggtctctacg ccgtgggcat tccgctgacc
     2401 tatgtgctgc gggacaaggg ggccgagcag tcctccggag ccgggcgagc ggaggtgatc
     2461 cccggatgag ccccgggttg cccacgcaga tgggcgagcg cgatgattcg gcgaacagat
     2521 gctcgccaat gagaacggat gttcggccga tggagacccg cgaaccgctg ggccgggtgg
     2581 cccggctgca ctatcagcac ggcatgaccc accaagagat cggtgagctg ctcgggttct
     2641 ccagggtgaa ggtcaccagg atgctcgccg aggcacgacg ggcaggaatc gtcgagatcc
     2701 acatccacgg tgaggccacc ccgttcggcg agctcgaagc ggaactgacc ggcgcattcg
     2761 gattggcggg ggcctggatc gcgccgagct tctccgaccc ggagcgcagt ctcgcctcgg
     2821 tcgggatggc cggagcggaa tgcctgaccg cgctggcccc gacggtgcgc accgtcgcgg
     2881 tgggcctttc ctcgagcgtg gccgcgatcg tggcgcacct gcgaccacag gagcaactgc
     2941 ccgaactggg gttcgtgccg ctggcgggca gctggggcgg cgcctcacgg ggtatgagcc
     3001 cacacgagct ggtgatcggg ttcggtgcgg cgttcggtgc gcggacctat cacctgcccg
     3061 cacccattct cgccaagacg gcggacgcgg cgaccgcttt cgccgccgat ccaggggtcc
     3121 ggcagacact gcgcctcgcc gcgggggccg aactgctgat cgccggggtc ggtgcggtgg
     3181 aggccggtag cggcatgctg gcggacacgc ttaccgagcg cgagcgagga cagctgacca
     3241 aacgcggcgc cgtcggagac atttccgccc ggttcttcga cagtgtgggc agcgcggtcg
     3301 aaagcaccgt ggacgagcgc gtggtcggga tgagcctgcg tgcactggcc agaattccgc
     3361 ggcgcgtcgc cgtcggcttc ggcgaccaga agatcaccgc actgcgcgcc gcgttgcgca
     3421 ccgggctgat gaaccatctc gtcaccgatg tggacaccgc gagaacgctg ttgcggacaa
     3481 ccaggaaagg gaactgacca tgcgcgacgc cgcgaccacg gacgaactga tcgagcgact
     3541 cgcggaggcc ggtgagctgg ccgtgcggag gggactcgtg ctggccagcg gtggcaatct
     3601 ctccgcacgc ctgcccggcg ccgaggagtt cgtggtcacc ggggcgggaa cctggctgga
     3661 ccggctcacc ccggaggact tcacagtgct gaacctcgac ggcgaggtcg tcggcgggaa
     3721 tccgtcgccg tccagcgaat ggaagctgca ccagcggacc tatcgggtgc gcgaggatgt
     3781 gaacgcggtg gtgcacatcc atccgcagca cgcggtgctc gtggacgcgc tcggtcatcc
     3841 ggtccggctg ttcaccctcg accacgccgc gtacgtcggc tcggtgggca gaaccgacta
     3901 ctacccgaac ggctccgacg aactggccga caccgccgcg gccgaggcga aacagcacaa
     3961 ctgcgtgatc ctgggcaacc acggctgctc tgcactcggg gacagcgtcg gcatggcgtt
     4021 ccggcgcgcg atgaacctgg aggaggcggc cacggcgacc tatcgggcac tgtgcctcgg
     4081 agacaccacg accgctttcc cggaggcggc cctgcggacg ctgcacgcct gagaggggag
     4141 aacggcatgc gcactgacgt ggtcacgctc ggtctgcaca tcctcgacat cctgggccgc
     4201 ccggtcaccc ggatcccgcc gggccaggag gtcgagctca tcgagcagat caccatgacc
     4261 gtggcgggca ccgctgccgc gaccgcggtc gacctggccc gcctcggcgt gcgcaccgct
     4321 tcggtcggtg cgatcggccg ggacgcgctc ggtgccttct tgcgtgagcg gatgaccatg
     4381 gaaggcgtcg actgcaccgg tctgtccgaa gtggacacag cgcagacctc ggcgacgatt
     4441 ctgccgatcc gcccggacgg cggacggcca ccgctgcacg tgatcggggc gagtgccgcc
     4501 ttgaccgagg accggatccc gtggtcactg ctggccgagg cgcgggtgct gcacttcggc
     4561 ggcagcggac tgctgcccgc gctcgacggc gagccgagtg tccggatcct tcagcgtgcc
     4621 aaggagatcg ggctcactgt gctgatggat ttcatcccca ccaaggatcc gcagttcccc
     4681 ggtcagctcg ccgcctgtct gccgtacgtg gactacctgc tgcccaacct ggaagacgcc
     4741 tgcttcgtcg cgggaaccga tgaccgggcg agcgcgatcg actggtgtca caggcgcggc
     4801 gtcggcgcca ccgtgctgac catgggagca gacggggtca gcattgccga acgcggcggc
     4861 gcggaacggt tgctgcccgc ctacgccgtc gacgtggtgg acaccaccgg gtgcggcgat
     4921 gcgttcagcg ccggattcat caccgcgctg ctcgacgggg cggacctcga acaggccgcc
     4981 gagctcggcc tcgcggcggg cagcctcgtc gccaccggtc tcggctccga tgcggggatc
     5041 accgatcgtt tcgggctcga ccagttcgcc accacgacca cacgcaagca gacaggagcg
     5101 tgaccatgct cgattccttt tcactgcaag gcaagaccgc cttcgtcacc ggcgcagctc
     5161 gggggatcgg cgcggcgatc gcgaacggat gggcacgggc cggggccgcc gttgcctgtt
     5221 tcgacctcga cgccgacagc gccgcggaac aggcagcgac gctgcgcggg ctcggcgccg
     5281 aggccatcgg gatcggcggt gatgtcaccg atgccgactc ggttgccgca gcggtaaggc
     5341 gcaccgtgga cgagctgggc gggctggaca tcgcgctcaa caacgcgggg atcgcccacc
     5401 aggcgcccgc cgaggaactg gagcccgccg attggcggcg gatgatcgac gtgaacctca
     5461 ccggcgtgtt cctctgcgct caagcgcagg cgcgcgtcat gctggaacgc ggcggcggct
     5521 cgatcgtgaa cctcgcctcc atgtccggtt ccatcgtgaa ccggggactg acccaggcgc
     5581 attacaactc ggcgaaagcg ggggtgatgc acctgaccaa atcgctcgcg gtggaatggg
     5641 ccgggcgcgg catccgggtc aactccatca gccccggcta caccctgacc cccatgacac
     5701 agcgcccgga agtcgccggt gccagggccg aatgggagga ccagaccccg atggggcgca
     5761 tggtggacat ggcggagctc gtcggcccgg cgatcttcct cgcctcccgg gcttcctcgg
     5821 cctgtaccgg actcgacctg gtcgcggact gcggtttcgt ctgctggtga ccggcgcgcg
     5881 gtcgggccat tcggcgagta gacatcgtcc ggcctcgccg agcgcctcga gttggcgcgc
     5941 gatcgcccga gctgtcaccg tggatcacgc cggtcccggc cgcctggatg aggtcggcgg
     6001 cgcgctgctc ggtgccctgg agccgtccgg tcaccgcgag gcggtggact cgcgcttcca
     6061 gggcacgctt gccggattgc gccgtgggcg agagccgcac tcggtccgga tcgctcgaca
     6121 agcggaaaac ggccgggttc gcgacaccga attcgatctg tgtccgccac tcggcacgaa
     6181 gctcatcgac cgggtccacg ccctgtgccg acgcggtctc gacggtcgcg gccttggtgg
     6241 gtgcatgacc ggccgtcatc tgctcggcgg gcccagccat tttcctgttg tgtgggcggt
     6301 gtgcaggatg tccaggtatg actcgaggtc gaatccctgg tgcgcggccc agctgtcgct
     6361 gtagtaggta tcggtgtaac gatcgccggg gtcgcacagc aacgccacga tgctgccccg
     6421 ggtgttttcg gcgcgcattt cgcagatgag gcgataggcg gcgaacaggc tggttccggt
     6481 ggacgctccc gcggtgagtc cggtgatcga gcgcaggaaa cggaccgccg cgaccgatgc
     6541 ggcatccggt acctggatca tgcggtccac gacggtggga atgaaactgg gttcgaatcg
     6601 tggtcgtcct attccttcga tccgagaggc gtgcccggtg cgaatcgcgc tgtcccggtg
     6661 tttccagccg gggaagaacg cggagttctc cgggtcgacg acgcagaggc gggtgtgccg
     6721 gcggtgatag cggaggaatc ggccgatggt ggccgaggtg ccacccgttc cggcgccggt
     6781 cacgatccat tcggggatcg ggaacggttc gtaggccagc tggtcgaaga tcgattcggc
     6841 tatgttgttg ttgccgcgcc agtcggtggc gcgctcggcg taggtgaact ggtccatgaa
     6901 gtggccgccg agctcgtcgg cgagccgggc cgattcctgg tagatcgtca cgggatcggt
     6961 gaccagatga caggttccgc cttctcgctc gatcatcgcg atcttggccg cgctggtcgt
     7021 ggccggcatc acggcgatga acggcaaccc gagcagtcgc gcgaagtagg cctccgagac
     7081 cgctgtcgat ccactcgacg cctcgacgat ggcggaccct tcggtgatcc atccgttgca
     7141 gagtgcgtag aggaacaagg aacgggcgag ccggtgtttg aggcttccgg tcggatgagt
     7201 ggattcatcc ttgaggtaca gctgaatgcc ccattggtgg gggagcggga cggtcagtag
     7261 gtgggtgtcc gcggagcggt tggcatcggc agtgacggtg ccgatagcac cgatgaccca
     7321 gtcgcgttcg gcgcggttcc atcgattcag gtcgatgatt tctttggctg gtgccgacac
     7381 ggctcagtcc tcttctgatg cgatgatcag ctcgacctcc acgggagcgc cgagcggcaa
     7441 cgatttgact ccgagcgcgc ttcgggcgtg ccgtccgcgg tccccgaaga cgcgaagcag
     7501 cagatcgctc gctccgttga tgaccagtgc gtgttcgatg aatccttcgg cactggcgac
     7561 gaatccggcc actttgacga tccggtcgag tctgtcgatg ccgcccgcga gatctgcggc
     7621 ggccgcgagt gcgttgagcg tgcacagctc ggcgagcttg ctcgcttcgt cgacggtgat
     7681 cgctgcgccg accagtccgg tcgcggcgag caaaccggcg cggaccggta gctgccccga
     7741 ggtgtagatc aggtcggcat gccgcaccgc ggcggcgtag aaacccgaag gagccgcgat
     7801 gggaggcagt gccagaccga ggctggtgag ttgctcgctg ggccgtgcgg gggccgatgc
     7861 catcgcgcgg ctgtggttcc cggtcatcgg ctgaccgttg ccttgcgcgt ggtgacggtg
     7921 aattccgggt gattctcgat ggtgttgtgc accttgcacc ggtttccggc gcggacgagc
     7981 gcctcgatct ggttctggga cagcgtgtcc gggaggacgt aggtgatgtg cagggtgctc
     8041 aaccgcatcg gccgggtcgc ggtgtcgccg gagagctcca cgtgggcgcc ggtggcgtcg
     8101 atgttgttgc tctgggcgta gtccatcatg gtggcgagca tgcatgcgcc gaggccggtg
     8161 aggaacagtt cggtggcctg ccacgtggaa tcgacggcgt cccattcgac tctcgcctcg
     8221 gtgcggccat tgtcgatcgt gaaggacaga tcccgggtgt ggcgtaccgt cactgggtag
     8281 tcggacatgc gtttcccttc tttcggtgct gttgcccctc aggcgatgga tgcggtgttg
     8341 agtcggtcga gcggtacgta ctcgtgctcg tagccgaaat aggacgggcc caccagtgca
     8401 agaccggccg gtgaccgcca acggggatgg catggcaagc cgatgaccgt gacgcggaag
     8461 ccgtaccgca tggcctcggt ggtgatcggt tccccggtgt cggcctcgag tacgcagatg
     8521 agatcgggaa cggacgcgac caccgcgccg tcgcgggtgg cgaggagatg ttcgttctgg
     8581 aaatgcagcg tcatgctcgc accggtgtcc ggaccggttc cctggatctc ggcctggccg
     8641 cgggcgaagc cggccttggt gcgccgccgg acgtcggtga ccctgccgtg gaagaggatc
     8701 acgccatcgg tttcggtgat cagcgcttcg accgggtcgc ggtggtcccc gcgtgtggcc
     8761 ctcaggagcc ggccgagccg cccggcgagg ctgacggtgt cgggaaccag tgccttccgc
     8821 gcttcacgac cggtcatcgg atagagcgcg atgcaggctc cgcagcccat ttcgacggtg
     8881 gcggaccggg ccagttgctc tgcccatgcg ttgtcgaccg tgtccagtag gacagtgttc
     8941 cctttgtcgt cgaccatggc catgggcgtg gtggagatgc cgtcgagggt ggcgaggacc
     9001 atctgcagtt ccgggaaagc ccggcccata ccgtccccgt cgatcagtgg caggttcgtc
     9061 tccgccgcgc agacaagggg catcatcgag ttcagcccgc cggcctcgaa gcaggcgatg
     9121 tgcgtgatcg tgctgccgta cgctgtctgc acggcgcgga cggcttgggc gaattcgccg
     9181 cctgccggtg gtttctccac gatgacggtc ggcgctccca tgattgccac cggcagcacg
     9241 acggcgtctt caggcaagtc gggcagcccg accgtccgta ccggcccgct gtcggtgatg
     9301 gcgcgttcgg ccatcaaagc tccgaggtgg ggatcaccgc caccaccggc gccgagaacg
     9361 gcagcgccgc gggcgatgtc ggcgatggcg ttcgcatcga tgtggttcac ggggtgtcct
     9421 ccaggatcag ctcgccgacg gctttgaccc gaacccggac ggcatcgccg ggcaggtagg
     9481 ccatgggcag ttcgtcgacc tcgacggtgc ggacgctgtc cggtgccgca ccggcgagga
     9541 tcgctttctc ggccgcctcc cgcttggcgt cctcgaggat cgcgtcccgg ccgcggccgg
     9601 tgtcggagta cacccggtcg acctcaccgc cgacctgggc gatcgccgca ccgatcgcgt
     9661 tggccacggt gaattcctcg gggcgcacga ccttgtcgaa cccgggcagg ttgtcgggca
     9721 gcagaatgct gccgccgccg acgagcacga tggggaccgc ctcggtcgag gtgcgcatcg
     9781 tgtcggcgtg ctcggcgacg cgcgcggcga tgtgatcaag ggtgtcgcgc acctggtttc
     9841 cgggcagatc cgcgatgagc gctggatccc cgaccgtgta caggcctccg gcgacggcga
     9901 tatcggtagc ggtgagggtg tccccgccga agacccggga cttcgcgtgc agctcgtatc
     9961 ccacgctttc cgggccgacg gtgatgcgtg agggatcgga atcgtcgacg atgcttccgc
    10021 ccccgatacc gatcgacacc acatccggca tccggaagtt cgtgcgcact ccggcaatgt
    10081 cgacggcggt ggtcgccggg cgggggaatc cattgacgac ggcaccgatg tcggcggtgg
    10141 tgccaccgac atcgacgacg atgcagtcgt tgagcccgga gagcatcgcc gcgccgcgca
    10201 tcgagttcgt cggcccggca gcgaaggtcg cgaccggata gcgccgcacg tagtcgatgt
    10261 ccatgagggt gccgtcgttc tgagacagat acagcggcgc gtcgatcccg gcccgggtca
    10321 gtgccacggc gaaggcctcg gtcgtccggt cggccacggg cagcagtgag gcgttgatga
    10381 tcgtggcgtt ttctctttcg agcagcccga tccggccgat ctcatgggag agtgagatgc
    10441 gcagcccggg tacctgcgag acgaggactt ccgcggccgc gagttcgtcg tcgcggttga
    10501 cgggggagaa gatggagctg atcgccgcgg aggtgatacc gcgttccccg atggtctcgg
    10561 cgacccggca cagttcgccc cggtcgagct cggagatctg ccggccgtcg aactcgtgac
    10621 cgccgtgaca caggaacacg tgctccccga cggcggcgcg cagccgggcc ggccacgcgg
    10681 tcaacggcgg gacgctggcc gatgcgggca gaccgagccg gatcgtcgcg gtcggcgcca
    10741 gtccacgtgc ctggacgacg gcgttggtga aatgggtggt tccgatcgcg acggcggaga
    10801 tgccggtcag atcgaaggtg acgttctcac tgagcccggt gatggcctcc acgatcccgg
    10861 tggtcacatc gagtgtggtc ggacgtttca ccgaggcggc gaccactccg tggtggatga
    10921 ggaccgcgtc ggtgttcgtc ccgccgacgt cgataccgat atgcatggct acccctggtc
    10981 cgtgttgtgc gcgatggcgg tgctggtggc ggagacgctc tccgattgcg aggcggtggc
    11041 acctcgtcga gcgatcaggc cgagctttcc caagacgatg taggcgaccg tggcgacagc
    11101 caaggaattg atcgccggta tcccgatgtc cacgaaatac cccacgaggc cgccggtgag
    11161 ccaggcgacg agaccggcgg ggacccagcc gggcgcggtc gccggtagtt cgccgcgccc
    11221 gcgtgaagcc tcgaggaccg gccgccaggt cttgacgatg aaatactcgg cgatgcagat
    11281 cccggccacc gggggcatca ggatcccgac gaagctcagg aaatcggtga agtaggcaag
    11341 gatgcccagc gcggagagcg ccgcgccgag gacccccacg acgatggtga ccacggcgcg
    11401 gttgaccttg cggccgagga gcacatgcag gacgttgacc agtccgagcg aggacgagta
    11461 gaggttccag tcgttgatct tcaggatcga ggcgacgagg accacggttc cgatcagccc
    11521 gctcgtcgtg gtgatcatca tgaccacatc ggaggtacgg gccgcgtgcg cgagaaggac
    11581 gccgatcacg ccgacgacgt actcgccgag tgtcacgccg atgaccgtct gtttcacgac
    11641 atcggccacg ctgcggttat agcgggtcat gtcgggggtc atcacggcgc cgacgatgaa
    11701 acccccggcg acgagtgtgg cccccgcggc gagcgagagc cggggcccgg ctggtgcgga
    11761 ggcgagcagg tctgcgatcg gatgccggga cagctcccgt gctactgccc agatggcgag
    11821 caccaggaac gccggaaccg tgacgtaggc ggtccaggtc atcccgccga agccgtacac
    11881 gacgaccgcg gtcacggcga caccgccgag cagcgaccag acccagaccg gcatggcgcc
    11941 gagcaccgag tgcagcccgg taccgaacac agcgttctgg acgccgaacc atccgatcag
    12001 gctgaccccg atcaacaggc cgaccaatgc cgaccccttc gtaccgaacc cggtccagcg
    12061 tgccagtacc gaggtggaga gcccttcgcg cataccggcg atacctacga agacggtgac
    12121 gatctcgagc agtaccgatc cgacggtgat cgccaggatg gcgttccaga atggcatgcc
    12181 gaaccccagc gtcgccccca ggaggaactg ggcgagagcc gagagctggc cgaaccgctg
    12241 aatcgcgatc gaccaccacg ggtaccgggc gtcggccggt acccgttcca gagcgtagtc
    12301 atcgtgcccg acgaccacgg tgtcatcaga gcgggatcga gacatggctg gaccttccgc
    12361 aacgggatca tcaggtgtga atccgggaat ggccccaagg taatgaagcg cttcgcagcg
    12421 cctcaatggt catactgtcg tagcagggtg tcgatacagt gcacgatgca cagccgcgtt
    12481 ctgaggtgat cgcatgaggc tcgaagatga tcaggtatcc gcactcgcga caggctgcgc
    12541 gttgctcggc tcgggcggcg gtggtgccac cgacgtggcc gaggtgctgt tgcgcggtgc
    12601 cctggccggc gctccggtgg agctcggtgc cgccgatcgg ctggccgagg acgccgtggt
    12661 cgccacggtc ggcgcggtgg ggtcgtcgac ggccatgctc gaacggattc ccagcgccga
    12721 ggagttcgtc cgggccgccc gcgccaccga agcgcgcctc ggccgaccac tcgccgccgt
    12781 ccagtctctc gagatcggag gtgtcaacgg cttgctcggc gcgtgtgtcg cggcatggct
    12841 cgggctgccg ttgctcgatg cggacgcgat ggggcgggct tacccgcgcc tgaacctgac
    12901 cacacttgcc ggccatgttc cgctcacccc cttggcgctc tcggctccgc gaggggaggt
    12961 gatcgtcatc gacacggccg acgagcgatc cgtggagtcg ctggtccggg cgatgctccc
    13021 cagcctgggg agctgggcgg cgatgtgcct gcacccggcg acggccgcgc agtaccgccg
    13081 ggcatcggtc cagttctcgc tgtccagggc gctcgacctc ggtcaccact ggcagcagcg
    13141 gcagcgtgga ctgctgacca cagcggagct gttcgaccgg acaggtgccc gccacctcta
    13201 cgaggggacg gtcgccgagg tgatcaggac acaaccagaa atcggtggcg tcgcgacaat
    13261 tcacgacgga ggcagcggat cggccatcat gcgcctggac ttcgccaacg aatacattct
    13321 cgcgttcgag gacggatacc ccgtcagctc cgtccccgag atcatcgtcg tcctcgatca
    13381 gcgaacctgg aaaccgatca gcgtcgagca actggccgtc cagcagcgag tgcgggtgct
    13441 cgcgctcccg gcgccgccgg aactgttcaa cggtcgccac gatgccgaga atcggttcgg
    13501 gctgcgagcc tatggccgcg agccggttca tccccaagga gccccggatg caactgctga
    13561 ccttcgatga tctgcgtgcc ctggaagtgc tcgaacactc caccgtggtc ggcgattctt
    13621 ccccgcacca cggcatagcc gccgtcgagg tgctcgaatc gcatgaagtg ctcgacaagc
    13681 cgctcgcgcc ccgctccgcc gtcctggtct gcctcgacga gtcgctggac cggcatcgcc
    13741 agcacctgct cgatctgctg ctacgacgcg cgcaccaggc gcgggccggc gcgatcatcg
    13801 ttctcggttc gaccggggaa atcccggcgg ccacccgatc actggccacg aaactcgcga
    13861 tcccggtcct gctcgctccc gcggggagct cgccactcac gaccgcggtc gagctccgtt
    13921 ccgcggtact cgaacccgaa ctcgcgatga gcaactgcct gctctcggtg acccgccagc
    13981 tcagcagtgg accccggaac ccgcaggaac tctgccatct tgtcgggaaa cccatccgtg
    14041 cgaacgtcgg tatctgcacc gcccaagggg ttttcatcgc cgggggcccg ctggaaacac
    14101 cggtcacaca gctgatcggg gggcacatac cggagagttt ccaccacggc gaccgcagta
    14161 tcgcggtaac gccgatcatc ggttccgggc agctcccggt cctctggagc atcgccgaac
    14221 gcgccggagg cggtccgttc tggcgtgagc tcgccctgca cgcacttgcc ctggcccgcg
    14281 gcgagatcac tgcctggctg gcccgcgagc aactgtccac cgagcgcgac gcgcgggtac
    14341 gcactaccct gctgaccgag atcgtggaac acgggaacgc aatccccgaa tcgatcgaac
    14401 aacaagccgt ttccgtcgga tggcagctgc tcggatggca caccggggtg catctgactt
    14461 tctcggcgag caccccgatg tccaccctgg ccatcgagac cctgaacacc gacctcgcga
    14521 agcccccact gtcgctcggt cctcttgtcg aacgcgccaa cggctggtcg gcatggacaa
    14581 cgacacagga tcagccgggc ccagagcacg cccggaccct ggcccgcgaa ctcgagagca
    14641 ggctccgcca gctcacggca cactatcccg gtctcacctg cgcggccggg gtcggcgcgg
    14701 cacaacgtga catcagcgga atcgccacca cactgtccca agcacgacag gccgcctcgg
    14761 tcgcctcggc ggaccggagc ccgataacgg tccgcgccgt ccaggacctc ggtgcctccc
    14821 ggctcttgct cggctggtac gcctccggtg ccttccacga ctacgcccgc caactgctcg
    14881 cgccgctgct cgaagcagcc gaaccagagc tccgcaccac gctcgagacc tacctggacc
    14941 gggcctgctc agcgatgcat acaagccgcg tgctcggtat ccaccgcaat accgtcagcc
    15001 tccggatttc ccgtatcgaa acacttctcg gtgcttcgct gaccgacgcc gatacgcgcc
    15061 tgaccctgca gctggcgctg cgggcactgc gggcgggctc cgcggcggac acggaacgat
    15121 gacacggccc gagtatcgcg gcacagccga gcggttctca ggtgacgtga ccgcaacggg
    15181 tctcggcgca ggtggcccca tggcggtgcc cggccctttt ggctcgcgaa tcgcatcggc
    15241 tcgatccgct gggcgagcgg gacgatttga tcgtgctgcg cgctgaacgg cttgacgtcg
    15301 ctccgtcgat gatccgggac catccttccg tgccggtgtc ggctcgactg gccacacgca
    15361 atcgaacaca gcgggtccgg cgcggttggt gcctcagtac gagagaaacg agctcttgtc
    15421 gtcgtcgggc ccatttcgca aagatcaggg ccgcgtgccg tcgcacggaa agataccgat
    15481 gcaagcggaa tctcggtgac gtatcgccac gattgcacgg cgtgtttcag gtctcggctg
    15541 tgaacgtcgt acggcagaaa tcagcaaatg cctgtgctcg gcgggtgagc cgggcagtac
    15601 acgcatggcg aacatgacct cgacggttcg tacgtcctcg aggatctcac ggtgcacgag
    15661 tggtgtgaat cgcccgcgcc gctcgcaaca agagagcggg ccgattcgag gctgtcaccg
    15721 tgaaaccggc atacgcgagg atccggcggg acggatgtcg gcgtggcggt gaccgtgtgg
    15781 acggtaccta gccgaacagc tccgggcggc gatcggcaag ataggggctc aactcgcggg
    15841 ccttcgcgat cgccgtgagg tcgagctcgg cgagccggag ctctccttcg ccgccgggcc
    15901 cgttcttctc gttcagtacc gccccgtccg ggccggcgat ccggctcagc ccgcagtagg
    15961 tgaggccctg accggtaccg ctccagttgg cgtaggcgat gaacagctgg ttttcgaagg
    16021 cgcgcgccgg gacgaggccg gtcgcgacga actggcaggg ctgcatcagc gcggtcggca
    16081 ccaccagcag ttgggttccg gcgagggcat gggcgcgcac ggcttccggg aactcgacgt
    16141 cgtagcagat gagtatgccg agggtgagcc cggcgagctc ggcctgccgc acgccgtcgt
    16201 cgccgggatc gaacgcggcg cgctccaccg agccgtacag atggcttttg cggtagcgca
    16261 gcaaggttgc tccgtccgca ccgaccagcc gggccgcgtt gtagacccgc tcgccgtcgg
    16321 cctcgggcca gccgtgcgcg atggcgatcc cggtctcggc ggcgattgcg gagaaccgcg
    16381 cgcagatcgg cccgtccgct ggttcggcga gcgaacgcag ccgcgtggcg tcggtcaggt
    16441 acccggtgcc ggagagctcc ggggtgacca gcagctgggc acctgaggcg gccgctttcc
    16501 gggctacggc ggccagccgg tccagggcgg tgctttccgc gccgtccgtg gcgacggcct
    16561 gccagcaggc gatcttcacg cccggaaact aagcgagccg cggcgatccg gcaaccccta
    16621 ctctgcgctt caaggggcgc caaccgcgcc gtgatggggc agactgcgtg ctatgggcat
    16681 accgcagcgg atcaaggtga tcgtggtgga cgatcagcag atcgtgcgtg agggcctggt
    16741 cgcgctgatg ggcctgctcg aggacatcga ggtggtcgga tcggcgccga acggtgcgct
    16801 cgcgatcgaa ctcgtcgacc gcctcgatga cctcgacgtg gtgctgatgg atttgaacat
    16861 gccggtgatg agcgggaccg aggcgacaaa gcggatcatg cgggaccacc cggatgtcgc
    16921 cgtggtcgtg ctgaccacgt attccgacga ccagacgatc gcggatgcgc tcgccgcggg
    16981 cgctcgcggt tatctgacca aggaagcggg ccgcaagcag atcggttccg cgctgcgttc
    17041 ggtggtcgcc gggcagatga ccttcggggc cgatgtgtcc cgtcaggtgg tcaatgtgtt
    17101 gttcgaatcg ggtgggcagg gctcgccggt gccgactggg gcgaaacccg ccgagcacaa
    17161 gacgggtccg ccagatgggc tgaccgcgcg cgaggccgag gtgcttggcc tgatcgcggc
    17221 cgggctgagc aatgccacga tcgcggccga gctgttcatc ggtgaggcga cggtgaaaac
    17281 gcacatcaat aatgcgttcg ccaagatcgg cgtgcgtaat cgcgccgagg cggtgcgcta
    17341 tgccgtgcgc aatgggctgg aaaaagaacc ggggtgatca ggcgaccacg gtttccttgc
    17401 gcggtcgcag ggcgagcttc gggttgttcg agcgcacccg gaattccttt gtccgaggca
    17461 cacggctgaa cagattgtcc gtaccgcaga agtgcagatc ggtgatctcg agccggtgta
    17521 gcgccgccgt cacctggggc cagtcgatgg ggcggtcgaa ggtgtccagc agcatccccc
    17581 gaatcccctc ggccgtccgc accagcgaac cgtcctgatc ggcgagcacc ggaatctccg
    17641 gatcgcgcag cgggcagtcg ccgaaggcgg accgctcggc tgtgtttcgc aacgcggtga
    17701 acgagggagc atgcaccggg ggacgcatgg tgtacagaga atagccgccg acctcgctga
    17761 ttcgcgtgat gaatccgtcg agttccccgg aatgcagcga gatcatatgg aatccctcgt
    17821 ccagcacccc ggagatctcg taccacgaga gctcgccgag taccgtgcgc cagccgtcct
    17881 cggggacccg catcacggtg tgcgtgacga catcctggtg ctgtacggcg aagtattcct
    17941 gttcgcacgc ggcctggatc gcggtcagcc gcaccgcgtc ggaaaagtcg agggccccgg
    18001 agaacaccgc ggccgccttc tgtccgaagc tcaccccggt cagcacgtcc gggcggagct
    18061 cgagctcgtc ggcgatggcg acgcagctga ccagaaacgc cagctgggcg gcggttccgt
    18121 agtcgtccgt gctgtcggcg taggcatcca ggaccgagta gccgatcgcg tcatcggcct
    18181 cggtgacacg ctgccgggcg gcccggttca gcagcaggaa tttggtgagc tcggcgaacc
    18241 ggttcggcgc catgcccggg aaaacgagcg cggtagggct catgccgcta ctccggattc
    18301 cgcgcgggcc agctcttcca tccgattctt gtccggtttt ccgttgcgat tgaccgggaa
    18361 tcggtccacc accacgaccc ggttcggctg ctcgtgcggg ggcaatgcct cggtgagcac
    18421 gctgcgccag tacccgcttt cccggcgctg cgggtcggcg acgaagaata cgagctggac
    18481 accctggcgt ttctcgggca gcgagatgat gcgcgcggtg cagccctgcg cggcgacttt
    18541 gcgctcgatc acctccggat ggatggtgta gcccatgcga tgcacggcgg acttgcggcc
    18601 gaggatgaac aggttccggt tctcgtccag gtaaccgagg tccccggtgc ggtgccagcc
    18661 ctgttcggcc ggggtgacca tggcgtcctc gcccagcagc ccggtcagca tgtcggggca
    18721 gtcgatgagc acctcgccga tctcggtcgc ggcgaggtcg cggtcgttct cgtccacgat
    18781 cctgcacccg atcccgtcca tcacctgacc ggtgccgacc ggattctcca gggtggcgaa
    18841 ggccaggttg cccagttcgg tgctgccata gctgtccagc agggtcatgc cgaactcgga
    18901 ctcgtactcg gcgacaagcg ggctgtccag cggggccgcg ccgctgcaca gcatccgggt
    18961 cttcatcagc gctgcccggg cttccgggcg tttgcccacg atgttcagca tgctctggta
    19021 tgtgctcgga gcggcgtcta ccacggtggc cccgcactgg ccggccatcc gcagtgcgtg
    19081 atccagcctg cggtaagggg cgatgatcag cgagcagcgg gtcaaccagg cgatcatcac
    19141 catggagatc ccgtactggt gggaaaacgg cagcagcggc aacagtacgt cgtctgcccg
    19201 gtgaccgacc tgatcagcat tgcgctgcat attcttcagg aaccgcgcgc cattcttgac
    19261 gatacccttg ggggcgccgg tggagcccga ggaccacatg atgatgctgt ccggcagggc
    19321 gcaccaccgg tcgaagcaca gccgacggcc cggtggcgcg gacgccgcat cggcgagcag
    19381 ttcgtagacg tagaccgggc tctggtcctg ggtgagtggg gcatcatcgt ccacgatgga
    19441 cattcgaacc ccggcacgtt cgatgatttc cccggtctgg ttcgctgtct cctgcgggtc
    19501 gacgagcacg atggacgcgc cgaggtgcat cagggcgaac agcgcgctca catacccgac
    19561 ggagttccct gccttgagca tgacccggtc gccgggcgaa agaccgcgcg cgctcagtgc
    19621 atcggccacc ccgagggtcc gcagctcgaa ctcgtcgaga gtctgcactg agtccacagc
    19681 aaagagtttg gcccgcatcg gtggcgtcct ttcgaatgga attggggatg cgctggatct
    19741 tcgagtgctc ccagtccgag gttgaatata ggaatgggtg accggagcac gccaccccta
    19801 atcgcccgtc gtggcctgcg tgggagatga gcggggtgtc taggggcggc taggggtggg
    19861 gagggtcggc agggctcggt agcctgccag caaggtgcgg gaattctcgg tcctatccag
    19921 gtgagttcgc cccagtccgt gtgcgagccg agttcagccg atccattcgc gaaaatgatt
    19981 gcgagaggac gaggaaaaaa atggtgaacc ccatccagga catcgggggt ctttccgatt
    20041 acgaccgttc tcgtgtcctc ggtgaattcg tccgggcaca ccttgccgcg gtcctcgagg
    20101 actggccggc ggccggtgtc gacgagcacc gctcctttct ggaactggga ctggactcgg
    20161 tcgccgcggt cgccctgcac gcgcggctga ccgaggccac cggactggaa ctcccggtga
    20221 cgctggcctt cgaccacccg aacacggcca gcctcgcggt atacctgcgc ggccgattgc
    20281 tcggcgagag caccgaagaa ccgagcgtga caccggtcgc ggccgcggag ggggagccga
    20341 tcgcgatcgt ggggatgagc acccgtttcc ctggtggagt cgccagcccg gaacagttct
    20401 gggagctgct cgccgaaggc cgcgacgcca cctccgagtt ccccaccgac cgcggctggg
    20461 atctggcggc gctctacgac gccgacccgg accggccggg caccacctac acccggcgcg
    20521 gcggtttcct gcacgatgcc gccgagttcg acgcggcgtt tttcggcatc aatccgcgcg
    20581 aggccctggc gatggacccg cagcagcggc tgctgctgga aagcggctgg cacgcgctcg
    20641 aggacgcggg catcgatccg gcggagctgc ggggcagccg aaccggggtc tacgtgggcg
    20701 ccgaagcaca ggactacgga ccgcggctgg aagaagccga gggcgccgag ggatacctgg
    20761 acatcggcac cgcgggcagc gtcgcgtccg ggcggatcgc gtacaccctc ggtttggagg
    20821 gacccgcggt caccgtggac actgcctgct cgtcctccct ggtcgcgctg catctcgcgg
    20881 tgcaggccct gcgccggggc gagtgcgcgc tcgcgctggc cgccggggta gcggtgatgt
    20941 ccagccctgg cgggttcctc tcgttcagcc gccagcgcgc gttgtccgcg gacggccgct
    21001 gccgggcctt cgccgccgac gcggacggca ccggctgggg cgagggggcc ggaaccgtgg
    21061 tgctggcccc gctttccgag gcacgcaggc gggggttgcg ggtgctcgcg ctggtcagcg
    21121 ggatcgcggt gaactccgat ggggcaagca atgggctcac cgcgccgagc ggaccggccc
    21181 agcaacgggt gatcgagcaa gcgctcgccg acgccggaat cccggcagcc gaggtggacg
    21241 ccgtcgaggc gcacggcacc gcgaccctgc tcggggatcc catcgaagcg aacgcactgc
    21301 aagccgttta cggcagcggc cgtcccgcgg agcaacccct gctgctcggc tcggtcaagt
    21361 ccaatatcgg gcacacccag gcggccgcgg gcctggccgg ggtgatcaag atggtgctgg
    21421 ccatgcgggc cgggacactg cctgccacct tgcacgtcga gacgccgacc ccgcacgtga
    21481 actgggccga tcgcggggtg gcgctgctga ccgaggcgtg cccgtggccg gccaccgacc
    21541 atccgcgccg tggcggggtg tcttcgttcg ggatgagtgg caccaatgcg cacgtgattc
    21601 tcgaatcagc cccggtggaa gcagcgtcgg aagaaccggt cacgtttccc gctccgtggc
    21661 cgctgccggt caccgcgcac accgcagcgg cgctgcgcgc gcaggccgcc gcgctggtgg
    21721 agtacgtgga ccggtacccg ctcgcggacc tcggcgccgc gctgggcacc acccgtgccg
    21781 cgctgcggca ccgcgcggtg gtgctggctg aggaccccga atcggcgcgg gcccagctgc
    21841 gcgcgctcgc cgcgggggag gacgcgccgg gggtgatccg gggacgcggc accgaaggcg
    21901 ggcttgccgt gctgctgcgt ggcgagctac cgcgcggtgc ctgcggtgcg ctctaccggg
    21961 cgtacccggt gttcgccacg gcgctcagcg aggcgtgcgc ggaactgaac ctgcaattgg
    22021 cgaccccgct gctcggcgcg ctgcttgccg aggcccccga gctcgagcag ccggagtacg
    22081 cggacgcggc ggcattcgcc tgcgatgtcg cgctgtaccg gctgttcgaa tcctggggcg
    22141 ggcacgcgga tctggtcgcc gggaccggga tcggtgaact cgccgcggcg catgtggccg
    22201 gggtgctctc gctcgcggat gcctgcgcgc tggccgggac gatcgcccgg ggtgcgggcg
    22261 cggccgagct gcgcaggctg accagggcgc tgtcgttcga ccgcccggcc acctccgtgc
    22321 tcgacatcgg caccggggaa ccggtggacg ccgggacgct ggccgacgcc gggcactggg
    22381 ccgggctcgg cgcacggaat acggtgcctt gccccgcatg gtccgagcgt caccaggtgc
    22441 gggccgtact ggagctgggc ggttccccgg tcgccaccgt ggccccgacc gaggccgcaa
    22501 ccgtgcccga agcgctggcc gcgctcttcg cgcaagggct cgagctcgac tggcgcgcgg
    22561 tctactccgg ccgcgacgtg cgggatgtgt gcttgcccgg ttatgccttc caacgggagc
    22621 gcttctggct gcctggcatc ggaacagccg ggagcccgcg cgaggtgggg caatccagtg
    22681 cggaacaccc gctgctcggc gcggtgctcg cgcatgcggc gaaggacgag ctcaccctga
    22741 ccgggcggct ggctcttgct gcccatccct ggcttggcga gcatcgggtg cgcggggccg
    22801 cgatcctgcc gggcaccgcg ttgctggagc ttgccgtgca ggccggtggc cacgtgggtg
    22861 cgcgcaccgt ggccgagctg accctgcacg ccccgctggt cttgccggaa tcggccggga
    22921 tgaccgtgca ggccaccgtg ggcgaaccgg acgccgaggg caaccgtggg tttgcagtgc
    22981 acgcgcgcca ggaggacatc ggcccgtgga ccaagcacgc ttccgggacg ctggccgtcg
    23041 cgccgctccc gccggggccc gaggtgccgc gcccggagac ggtgggcgtg gccgccgatg
    23101 cggtttatgc ggcgctcgcc gagaccggac tggactatgg gcgcacgttc cgtgggctgc
    23161 acaccgcgtg gcgcagcggg gacgaggtga tcgccgagct cgtgctgccg gacggcgccc
    23221 cggatgggtt cgccctgcat ccggtgctct ccgatgccgc tttgcacgca ctggaactgt
    23281 tcgacggcgc cttcggcagc gatggccgcg cctggctgcc gttctccttc ggcggggtca
    23341 ccgtgcacgc cacgggtgcg cgccgcgcgc gggtgcggat gaccaagacc ggaacggaca
    23401 cggtggcgct gactgtggcc gggcacgacg ggaccccgat cgccaccgtg gaatcgctga
    23461 gcctgcgtcc ggtatccgcg gtggccgatg cgttgtaccg caccggctgg gtgccgctga
    23521 gccggtcgcg gccggacgaa cccggcgcaa gctgggcggt gctgggcgcg ccggtcccgg
    23581 aactggatgc gcccgcgcac ccggacctgc ccgccctgct gctttccgag ctgccggagt
    23641 tcgtgctggc cccggtcgcc ccgagggagg cgcatgcggc cgccggcgac gtgctcgact
    23701 tgctcaatgc ctggctgcgg gtgccgagga ccgcggactc ccggctggtg gtgctgacca
    23761 ccggggcgct cgcgaccgat gcggcggaca ccgttcccgg tctcgatcat gccccggtga
    23821 ccggattggt gcgcgccgcg caggatgagg aaaccggccg gatccttttg gtggacaccg
    23881 atgacagcgc ggcaagccgg accgtgctcg ccgaagcggt ttccgcggcg gtggccgaag
    23941 gggagaccga actcgcactg cgcgaaggca gggctttcat tcctcggctg tccacaacgg
    24001 acgctcatcc gtccacagtg gacgttccgg gcctcgatcc cgaaggcacc gtgctcatca
    24061 ccggcggcac cggggtgctc ggtggttcgc tcgcccggca tctggtgtgc gagcacggga
    24121 tccggcacct tgtgctgctc gggcgcagcg cccgcgaggg agaactggac gcggaactcg
    24181 ccgcgctcgg tgccgaggtc agcgtggtcg cctgcgatgt ggccgataag gatgcgctcg
    24241 ccgcggtgct cgccgacata ccggagaacc ggccgctgac cgcggtggtg catgccgcgg
    24301 ggaccctcga cgatggggtg ctcggttcgc tcacccggac gcggctgtcc acggtgctga
    24361 caccgaaggt cgatgcggcg ctgcacctgc acgagctgac caaggatctg ccgctcgccg
    24421 ccttcgtgct gttctcctcc tccgccgcgc tgctcggggc cgccggtcag gcgaactacg
    24481 ccgccgcgaa caccttcctg gacgcgctcg cccagcaccg ccgtgctcac ggtctgcccg
    24541 cgctttccct gcagtggggc ctgtgggagc aggcgagtgg gcttaccgcg cggctcggtg
    24601 aggctgatca tgcgcggctg cggcgttccg ggctcgcccc gctgccgacc gagcgagcgc
    24661 tcgcgatgtt cgatgcggcg ctgcgtaccg gaaattccgt tgtggcaccg atcatcctgg
    24721 atcatccggc ggtgcgggcg aaggtcgaga ccgatggtgg cgccccgctg ttgcgcggcc
    24781 tggcgggggc gaaaccccgg atcgcggcgg tggccgagga cgctcccgtg gccgagcagc
    24841 acggctcacc ggaccagctg atcgatctgg tgcgcgagca tgtggccgcg gtgctcgggc
    24901 atgccgcgcc gcacgccgtc gaggtcgatc aggcgttcac cgaactgggt ttcgattccc
    24961 tgaccgcggt ggaactgcgc aaccggctgg gcaccgcgct ggaccggcgg ttgcccgcga
    25021 cgctgatctt cgactacccg aatccggccg cgctggcccg ccacctcgcc gaggagtccg
    25081 ggggcggcgc ggcagtccgc acaccggcca ccgtggtgca ggacgctggg gaaccggtgg
    25141 cgatcgtcgg catgggtgcc cgattcccgg gcggggtagc cggtccggac gacctgtggc
    25201 ggctggtcgc cgagggcgtg gatgccatcg gggagttccc ggacgaccgg ggctgggacc
    25261 tggacgcgct ctatgatccg gatccggatg tgccgggcaa gatgtatgtg cgcaacggag
    25321 gttttctgcc cgatgcgctg gacttcgatg cggagttctt cgggatttct ccgcgtgagg
    25381 ctgtggcgat ggatccgcag cagcgccagc tgatggaggt cgcctgggaa gccctcgagc
    25441 atgccgggat cgacccgaac agcctcaagg gcagccgcac cggagtgttc gccgggatca
    25501 tgtaccacga tcacgcggcg cggctgcgcg agattcctga ggagctggaa gggtttctcg
    25561 gcaacggcag cgcggcgagc gtgctcaccg gccggatcgc ctacaccctc gggctcgagg
    25621 gacccgcgat gtcggtggac accgcatgct cgtcttcgct ggtatcgctg cacctcgcgg
    25681 cgcaggcgct gcggcgcggg gaagccacgt tggcactggc cggtggggtc acggtgctgt
    25741 ccacccccga ggtcttcgtg gacttcagcc gccagcgcgg actctccccg gatggccgct
    25801 gccgggcgtt tgccgaggaa gccgacggca ccggctgggc cgagggtgtc gggatgttgg
    25861 tgttggagcg gctttccgat gcggtgagca acggtcatga ggtgttggcg gtggtgcgtg
    25921 gttccgcggt gaattccgat ggcgcctcca atggtctttc cgcgcccaac ggaccgagcc
    25981 agcagcgggt gattgaggct gcgcttgtgg atgcgcggtt gggtgctggg gatgtggatg
    26041 tggtggaggc gcatgggact ggtactgcgt tgggggatcc gattgaggtt caggcgttgc
    26101 aggcggtgta tggcaaggat cgcgagccgg ggcgtccact gtggttgggt tcgttgaagt
    26161 cgaatctggg gcatgctcag gctgctgcgg gtgtgggtgg ggtgatcaaa ctggtgcagg
    26221 cgctgcgagc gggcctgctg ccgaggactt tgcacgcgtc gaggccgtcg gcgaagattg
    26281 agtgggatgg tgggggtgtt gagttgttgc aggagtcccg tgcgtggacc tccgatggcc
    26341 cgcgccgggg tgcggtgtcg tcgtttggga ttagtgggac gaatgcgcat gtgattttgg
    26401 agcaggctcc ggagagcgcc accgaggccg aaaccgcgac cggggctggt ccggtgccgg
    26461 tggtggtgtc tgggaagact cgggaggcgt tgcggggtca ggcttcgcgg ttggctgagt
    26521 gtgtgcgggt gcatccggag ttttcggtgg cggatattgg ctattcgttg gcgaccgggc
    26581 gggcggagtt cgcgcatcgt ggtgtggtgg tggcggggga tcgtggggag ttgttggctg
    26641 ggctggaggg cctggctgcg ggtgcggaat ccgcgctgac cggttcgggt tcggtcgcag
    26701 cgagccgggt gttgatggtg tttccgggtc agggttcgca gtgggttggt atgggtttgg
    26761 aact
//
