LOCUS       NZ_KB905390            21512 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Sciscionella marina DSM 45152 A37UDRAFT_scaffold_18.19, whole genome
            shotgun sequence.
ACCESSION   NZ_KB905390
VERSION     NZ_KB905390.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Sciscionella marina DSM 45152
  ORGANISM  Sciscionella marina DSM 45152
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Sciscionella.
REFERENCE   1  (bases 1 to 112116)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Sciscionella marina DSM 45152
            collection_date                   :: SEP 2006
            lat_lon                           :: Missing
            depth                             :: 516 m
            alt_elev                          :: Missing
            country                           :: China
            num_replicons                     :: Missing
            ref_biomaterial                   :: DSM 45152
            biotic_relationship               :: Free living
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: 19196758
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Sand; Sediment; Marine; Aquatic
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi11892
            Current Finishing Status          :: Level 2: High-Quality Draft
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2012
            Isolation Site :: Marine sand sediment at a depth of about 500 m,
            the northern South China Sea
            Cell Shape                        :: Rod-shaped
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28 C
            pH                                :: 7
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000379465.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 01:37:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,209
            CDSs (total)                      :: 8,146
            Genes (coding)                    :: 7,961
            CDSs (with protein)               :: 7,961
            Genes (RNA)                       :: 63
            rRNAs                             :: 4, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 185
            CDSs (without protein)            :: 185
            Pseudo Genes (ambiguous residues) :: 1 of 185
            Pseudo Genes (frameshifted)       :: 52 of 185
            Pseudo Genes (incomplete)         :: 155 of 185
            Pseudo Genes (internal stop)      :: 15 of 185
            Pseudo Genes (multiple problems)  :: 34 of 185
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:59:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 80026
            Orig. end                         :: 101538
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB905390.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405877
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Nikos  Kyrpides (nckyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-PGF and JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21512
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21512
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21512
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11512](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11512
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(570..1880)
                     /locus_tag="A37U_RS0116100"
     CDS             complement(570..1880)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024910.4"
                     /locus_tag="A37U_RS0116100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="APC family permease"
                     /protein_id="WP_020497679.1"
                     /transl_table=11
                     /translation="MSESPGLRRTLSARDLIVYGLLFIGPTAPIGIFGVLDAASDGASA
                     LVFVVATLVVGFTAWSYARMSAAVPRAGSVSAYATAGLGRAPGFFAGWLAGLDYLFIPS
                     VAALLSGTALHSTAPAIPTWLATGVAICVFTALNLAGARIAARVGMIVLAVGLVLLFVF
                     VVCAIVVLAEHGPARGWFSPLTGTGGLTMGALLGAASVAALSFLGFDAIAGFAEENTGG
                     PEQVGKALVFCLGLAGVLFVIQTYLASLISPVAPEQLAAHPQDQGTAFYTLIHSAIGGW
                     LGISVSVYKAIGPVFSALVAQAAAGRLLYGMASQGHLPGWLATVSPKTRTPRTAILLSA
                     ACTAAIAVWAALQPDGLDTLSSMVTVGALTAFVLLHASAIRYFGKRRGAGPWLLIPFAG
                     TVLTIALLASASRLALLIAAGWLVIGVLAYLIARART"
     gene            2018..2704
                     /locus_tag="A37U_RS0116105"
     CDS             2018..2704
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010696290.1"
                     /locus_tag="A37U_RS0116105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_051111653.1"
                     /transl_table=11
                     /translation="MTKLSGVVNEEPVPAGAQVADALRVRITEGGLPPGTQLRDTALAA
                     EFGIARHTLRNALRQLEYEGLISYRMHKGAVVKTLCTEDVHEIYRVRRTLELAAVQQSA
                     LAGSAALRGLEERVRAAEVAVACESWNTVGTASLWFHQALVELLGSRSIDRFFQGILAQ
                     LRLAFAVMPDEAQWQPPWIPRDREICDLVRGGQRGAAIAATRQYLEDSELAVLDVVRAD
                     EMTGRT"
     gene            2701..3534
                     /locus_tag="A37U_RS0116110"
     CDS             2701..3534
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011874858.1"
                     /locus_tag="A37U_RS0116110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1989 domain-containing protein"
                     /protein_id="WP_020497681.1"
                     /transl_table=11
                     /translation="MTVVAAAYESGEGALDVDRDFYRSLAETRHELVDAFEIPIRTGKA
                     WTVPEGHLCRLVTVDGPQVGDLNIWNAADPRERLWAARTRQLQRAHVSTFERLWSNLPF
                     LRPLVTVTADTLAGYGQDADGGRVHDLLGSRCDPYVNRMLTGEDFDYHCHSNLVRAVLP
                     YGLTEFDVHDVLNVFQCTGLNEEDRYFMKACPARPGDYFEFFAELELLCALSTCPGGDL
                     SVPMWGPDAGDPLEVCHPIGVEVYRPDPALLRDWRRPERAAYAGGHGLRAPAWPS"
     gene            complement(3544..4128)
                     /locus_tag="A37U_RS0116115"
     CDS             complement(3544..4128)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013053.4"
                     /locus_tag="A37U_RS0116115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="WP_020497682.1"
                     /transl_table=11
                     /translation="MTDTIDPRHSALLVMDYQNGIIGSLPDAEALLERAAGAISLMRDR
                     GGHIGYVRVAFTEEDFDRIPPSSIMAAMVTPERRAAMHAEAPATAVHERLAPEPGDIQV
                     RKTRIGAFSTTDLDEQLRAREVHTLVLAGVATSGVVLSTVIEAVDRDYRVVLLTDACGD
                     ADPELHTLLTERMLGKRARLSSTTELPSLLG"
     gene            complement(4143..5513)
                     /locus_tag="A37U_RS0116120"
     CDS             complement(4143..5513)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637327.1"
                     /locus_tag="A37U_RS0116120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_020497683.1"
                     /transl_table=11
                     /translation="MKPRERFAALSEGFDRKLLAPMISGAILNPVNSSIISVSLVPIGA
                     AFGAPPTATAWLVSALYLATAVGQPVAGKLIDVHGPRRLFLGASVLVGLAGILGMLAPD
                     LGVLIVARVLLGFGTCAGYPAAMRMIRDEAERTGKDSPTAVLTVLAMATQTIAVIGPPL
                     GGLLIGLGGWRATLGVNIPFAILAFVLGARRIPATARKTTNRPNLDFLGMALFAGMLVS
                     LLLFLMHPSATDWYLPLITVVAAIAFVLRELRSTEPFIDVRMLAGNRPLVATYARALLA
                     YIVSYAFLYGYTQWLEDGRGLTAAQAGLIQLPVFATAVVVSGLTGRRKEVRAKLGAGAL
                     CQILACALMLVLWPESGIWLLVTIALIFGITQGLMSLALQNSVYHQADPDSIGTSAGLL
                     RTFSYLGAIIASAAQGGFYGQHADTGGLHQLATFLLVMGGLLLLITLADRKLGRTTN"
     gene            complement(5510..5947)
                     /locus_tag="A37U_RS0116125"
     CDS             complement(5510..5947)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637326.1"
                     /locus_tag="A37U_RS0116125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_020497684.1"
                     /transl_table=11
                     /translation="MAEISTEAAKAAQDLRVLFSRLRRRLLDSAATEDLNASQTSVLAR
                     LVKDGPSSASVLAGAERVRPQSMATTLTALEKHGLIERAPDPGDGRRQVITLTAAGRKQ
                     GHGARASREEWLARSIQERYTAAERATIIEAIALLDRVVQQ"
     misc_feature    complement(5976..5994)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.97"
                     /tool="antismash"
     gene            complement(5989..7026)
                     /locus_tag="A37U_RS0116130"
     CDS             complement(5989..7026)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657428.1"
                     /locus_tag="A37U_RS0116130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_020497685.1"
                     /transl_table=11
                     /translation="MRTATTVEASGGPDWKQTGEFVVEAEKLGLDVCWVAEAWGSDAPS
                     ALGYYAARTERMLLGSGIMQLGVRSPVATAQAAITLANLSGGRFLLGLGASGPQVIEGL
                     HGVPFQRPLSRMRQTVEVLRQARSGEKISVPGRIPLPGSETRPMRLSARAEHPIPVYLA
                     ALSPAMLRLTGELADGWLGTSFVPEGADAYLAHLDHGLRDSGRTRADLDLCQGAEVAFA
                     PDADALPGMLAARKTGLAFSLGGMGTADTNFYNRAYGRQGWAEVAAEVSARWQAGDRTG
                     AAELVPDEMVLATTLIGTEAMVRERLRTWRDTGIDTVRLYPAGESLTEKLDTLGRAIEL
                     VHELD"
     gene            complement(7026..7532)
                     /locus_tag="A37U_RS0116135"
     CDS             complement(7026..7532)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (11-167). E-value:
                     3.9e-21. Score: 67.9. Matches aSDomain:
                     nrpspksdomains_A37U_RS0116135_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017981612.1"
                     /locus_tag="A37U_RS0116135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC family protein"
                     /protein_id="WP_026197274.1"
                     /transl_table=11
                     /translation="MESTGLRLAEAPSVEVDRWIAAAPERVWELVSDVTAMPAMSTELQ
                     AAEWLDGASGPALGARFRGHNRNDILGDWSTDSQVIECIPGQVFAWAVSDPDNPNAVWR
                     FRLEPENDGTRLRQYAQLGPGPSGLTLAIARMPEKEDRILRRRLRDVEQFMTDTLDHVK
                     TTAEA"
     aSDomain        complement(7032..7499)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A37U_RS0116135_Polyketide_cyc2.1
                     "
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="3.90E-21"
                     /label="A37U_RS0116135_Polyketide_cyc2.1"
                     /locus_tag="A37U_RS0116135"
                     /protein_end="167"
                     /protein_start="11"
                     /score="67.9"
                     /tool="antismash"
                     /translation="PSVEVDRWIAAAPERVWELVSDVTAMPAMSTELQAAEWLDGASGP
                     ALGARFRGHNRNDILGDWSTDSQVIECIPGQVFAWAVSDPDNPNAVWRFRLEPENDGTR
                     LRQYAQLGPGPSGLTLAIARMPEKEDRILRRRLRDVEQFMTDTLDHVKTTAE"
     misc_feature    complement(7515..7517)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(7559..7571)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            complement(7581..8072)
                     /locus_tag="A37U_RS0116140"
     CDS             complement(7581..8072)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640856.1"
                     /locus_tag="A37U_RS0116140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_020497687.1"
                     /transl_table=11
                     /translation="MKHTSFADWPCSIARTVDLLGDRWAPLVLRECFYGLRRFDEFQRE
                     LGIARNTLTERLRRLVADGLLEKRAYQREPMRHEYLLTEQGRDFFGVLAAMARWGDRWL
                     AGEQGPPVLLHHACGADSHAEVVCAACGEPMRAGNTRARMGPGFPEALADRTSVRKRFS
                     "
     misc_feature    complement(7734..7736)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8092..8655)
                     /locus_tag="A37U_RS0116145"
     CDS             complement(8092..8655)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018984.4"
                     /locus_tag="A37U_RS0116145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_205622949.1"
                     /transl_table=11
                     /translation="MASEQLRFDTGRVCLDLLATVGSRLSEHPVERLNGPDRLHAWFTG
                     TGLLPADQPIAIGPDWFAQVDRVRTLLHRIVQDTVHGRTVPVSRVRALNELAGQTPPIP
                     RLRTDARTVRLREPVTLAGLLSLVARDAIELLSGSERQYLRECAGGDCDLVYLDHSRGR
                     RRRWCSSRVCGNRERVANYRERLG"
     misc_feature    complement(8512..8514)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8661..9881)
                     /locus_tag="A37U_RS0116150"
     CDS             complement(8661..9881)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="A37U_RS0116150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_020497689.1"
                     /transl_table=11
                     /translation="MTLTHYMNPALRGFGAHHRWLILGIGVAAQASFSAAFAGIPATGP
                     LLRGRYHFSAGQLGLVLGAILLGIAISEVPWGMVTDRLGDRRTLLTGLLGTGALLALLA
                     VVLTPGAPALVFAAALLLVGVLGGSVNGSSGRAVMAWFPDDRRGFAMSIRQTAIPAGGA
                     LGAALLPVLAGDLGFRAVFGALALFCFASAAAAFAWLHEPAESTAQPRGIGGSPLRSRA
                     VWRLASASGLLSVPQFAVTTFASVFLVSQRHTHLALGTVTLLIVQLGGAAARVWSGGYT
                     DRHGNRRGYIKAVAGLSTVAFAGAAVLTEAPVGLTVAALAAGGLLASAWHGVAYTEIAR
                     MAGTRRAGTALGLENTTVFAAGFLAPVLIPVLADGASWAAVWAGAGACCLLATLVSPGR
                     HNSPEGM"
     misc_feature    complement(9519..9521)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..11512
                     /locus_tag="A37U_RS43980"
     CDS             10001..11512
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.4"
                     /locus_tag="A37U_RS43980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_020497690.1"
                     /sec_met_domain="T2TS (E-value: 9e-69, bitscore: 225.3,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDFRSAANTLLHESAADPWAWLTPSVYECARLVADAPWLGGHA
                     ERLRHLCRTVTADGTWGQDGFAFNATLSATEALLAVAQRREPADEVIERGKARAVAGQG
                     LRALRDWLAPGGRYAAGPPATISVELIVPMLVDRINTRLAAAGEPELPMPAGCATERLA
                     AIRADAAAGRELPADIWHAWEIATPVDSAHPYAGSVSCSAAGTAGWLRTASDPGSPAAR
                     FLEELQRHGNGLVPVAAPIDYFEHAWMLNTFVWHRVPHDCPERILDRLESELGPHGIAG
                     GRDLTVDGDDTAAVVNALLCHGRTAGLDGLLTYWAEDHFQIYPGESIASPATNGHTVSL
                     LHRYLAERPEHGERYGPVLRRNTEWLLDQQRADGSWFDFWHVSPYYATVCAVEALSAVD
                     GEPAKAAARRARRWVLDTRHPGGGWGVRWVTMEETAYAALILRGSTETGVAEALTCAEP
                     VLRDGVVDAGITPLWLVKDYFAPIRVVAAAVLAARQAILTGQRGA"
     gene            complement(11497..12711)
                     /locus_tag="A37U_RS0116160"
     CDS             complement(11497..12711)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017984044.1"
                     /locus_tag="A37U_RS0116160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_020497691.1"
                     /sec_met_domain="p450 (E-value: 1.7e-18, bitscore: 59.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEPIRLGEQFLQDPYQLYDRLRAEQPVAPALLPHGLRVWIVSRY
                     ADARAALADPRLRKDSVRQQELSARQAEETNSTPVITEFLNSHMLNTDPPDHTRLRKLV
                     GATFTSRRVAELRPRITEIAGELLDALPRGEVVDLVHGFAYPLPITVICELLGVPESDR
                     ADFRSWTATLLNTGVGAQELAAASEAMVGYLDALIAQKQLTPGQDLLSALVEAREAGDR
                     LDEGELRAMVFVLLVGGHETMVNLIGNGTLALLRNPDQLAALRADPAGLPAAIEEFLRY
                     DGPVNFATFRFTTEDVPIGETSIPAGEFVVVALLSANRDAQRFTDPRELDLDRATTGHL
                     AFGHGVHYCIGAQLARAQAEIAFGMLLERFPEIRLAVAPGELTWRHSTLMRGLEALPVL
                     LQAPR"
     gene            complement(12708..13745)
                     /locus_tag="A37U_RS0116165"
     CDS             complement(12708..13745)
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (extras)
                     Sulfotransfer_3: Sulfotransferase domain"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024860.4"
                     /locus_tag="A37U_RS0116165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfotransferase"
                     /protein_id="WP_020497692.1"
                     /transl_table=11
                     /translation="MRSLNFVVGTGRCGSTALSRVLAGHPDVLSLNELFASLAPGTFPP
                     GPLTGAEFWRLLAEPNPFFDAMARERSRVPEFLYPRDPGRFSPETGIPAIAMMALPHLS
                     EEPDALFDELAEQIPSWPARPVTEHYAALFALLGRRFGRTAVVERSGFSLQWIGTLADR
                     FPAARLVHMFREGPDCALSMSRHPGFRLVVLENRIKALTGARAIPELRPADVAALPPEL
                     AKVLPDRFDPAVLEQPIPLAEFAELWTAQIRDAVTGLAELPAERRCTIGYEDLVAHPRA
                     ELARLAAFLDVEPDPSWLATAERLLDRNRVGGAAALPAEELDRLRELCEPGRRALQAQR
                     REVAP"
     misc_feature    13811..13829
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.31"
                     /tool="antismash"
     gene            13861..14886
                     /locus_tag="A37U_RS43985"
     CDS             13861..14886
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="A37U_RS43985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class 1 isoprenoid biosynthesis enzyme"
                     /protein_id="WP_157182861.1"
                     /transl_table=11
                     /translation="MPTDSEHAERQIRLLSGQVEQTMAELVAEYTSEHGQLRAIVPTVV
                     REARADRHEFALPLLVHGAETGDPAAAVPIAAVHALWWRAANIIDDLADDQAGEAARRI
                     GPGATMLVAFNWAYVLPARVTSALPVAEPVRSALTTEFLQSCTAATEGQLADLFTEPGE
                     LSHDQVLRTYLNKSSAPYVMASAMAARTAGADDARTEGWRRFGRNLGLLGQFRNDQEDL
                     QSGRMEDLANATPTFHLVSLLNSGHGARRERVLALLRRARTDTHAREELLERMLDPEVV
                     RPYLAHIEGVRHEAEQVLDELSLDELGGSGCFVAALRGRVRAAATPCELLAGVANPAEA
                     S"
     gene            complement(14913..16070)
                     /locus_tag="A37U_RS49730"
     CDS             complement(14913..16070)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014741.4"
                     /locus_tag="A37U_RS49730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_020497694.1"
                     /transl_table=11
                     /translation="MNGLGSREFEDALVESTCSYRTEQARLDHRILIDVHQLWRSQAAR
                     FGEELARDSVIEELRLAWCCYRGKAIGTVELSVEMHERFPELLSCMSEGLLDSFLASKA
                     TEVLRPLTPELAAIADRRIAQRLREQGLPHDWRAYLRRIADSLDPTAKQKRLAQARAAR
                     YVSFQDEEDGTGTVFARIPAEDSHACETRIRDLARAIRQRGDTRTQEQIRADVFTDLLL
                     GRGDDHPPVHTVVNVHVPLGTALQLNNSTAIVDGMGEIPAHVARQLLADPNNVVRKVLT
                     DPDTGVVQGLGRKRYRPTRRQRDFVHIRDRHCRAPGCRRPIVEIDHVEQWHRDHGTTDP
                     ANLQGLCRINHKLKRMPDWKHQLDPTTARLTITTPTGREYTSTPG"
     misc_feature    complement(15690..15692)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15810..15812)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16167..17420)
                     /locus_tag="A37U_RS0116180"
     CDS             complement(16167..17420)
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983136.1"
                     /locus_tag="A37U_RS0116180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidohydrolase"
                     /protein_id="WP_020497695.1"
                     /transl_table=11
                     /translation="MTELRALRRRLHAYPETGFTEIVTAATVIGELRAAGIEPCYGEQV
                     CVVEGLAGLPDPAELAAARERAAVQGVAPELIDTLSGGRTGILAEVHGNRPGPVLGIRF
                     DMDALPVTEAGEAAHFPAAEGFASTREGVMHACGHDGHTAIGVELGSRLAADPDFPGTV
                     RLLFQPAEEGVRGARALVEAGACTGIGTILALHLGLGLEVGTVAAAARGMLATVKLRVR
                     LTGRAAHAALAPNEGRNALLAATHAANALHAMPPIPGIATRVNVGTLRAGTAANIVPEH
                     AELGMELRAETTAACAELIERARAILEGAAHMHGVELEIAETGKATAAVHDEAVCAGIT
                     AAAQATAGVRECLAEAPMSASDDATLLLDAVREQGGTGAYFLVGAANPAPHHHGRFDID
                     ERSLPIAVELLERFVRAR"
     gene            complement(17417..18604)
                     /locus_tag="A37U_RS43995"
     CDS             complement(17417..18604)
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01891.1"
                     /locus_tag="A37U_RS43995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidohydrolase"
                     /protein_id="WP_020497696.1"
                     /transl_table=11
                     /translation="MNATAHTAIDASIEDNRKALTELSLDLHANPELALAEKYAAGRLT
                     GLLEEHGFQVTRGIAELPTAFRAESGSGSPRIAFLCEYDALPDIGHGCGHNLIATGGLA
                     AGIAAARARQAAGLDGTVCVIGTPGEEGAGGKITELEAGVFADIDAALMFHPGDRTVPI
                     RHATAAQSITVEYHGIAAHAAGSPQDGRSALAALIQLFVAMDTMRQFVPETVRMHGVIT
                     EGGQAPNVVPEYASGKFQIRDISSESVVELVERFNEAAHGTAAATGTKVELTYGPLYAE
                     RKNNHPLAYRVADYLRGQGIPVSEPVLRGGTGSSDIGNVSLELPAIHPYLAIMPEGTAS
                     HSRAMTEYAATDSAHTSMFAMARALACAGADLLADPVFLAHVRQDFATRAPDYPR"
     gene            complement(18601..19671)
                     /locus_tag="A37U_RS44000"
     CDS             complement(18601..19671)
                     /EC_number="3.4.13.-"
                     /GO_function="GO:0070573 - metallodipeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013413.4"
                     /locus_tag="A37U_RS44000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="membrane dipeptidase"
                     /protein_id="WP_020497697.1"
                     /transl_table=11
                     /translation="MSQGSVPPQPVVPLATDRDRVASPAPELSSGQRERLADILAGPTV
                     SLHDHPVRLPDPLNERSWIRFADSGQVFLGETGLSTVFASKLAGGTLDEAVAFGTAVTA
                     QQNSGAATSDTTVLGALEDLGPIGTELRGLDALYGAGIRCAGLAYNTGTALAGGLGQDP
                     DPGLSPVGRGAVRAMEELGMLVDLAHVGDRSSIEAARLATRPLVISHAGARTVWPTPRM
                     KPDEVLRAVASTGGLIGIEAAPGSTRSRASSGDHDLDDVMHHLEYCAELIGIEHVALGP
                     DTFFGDHLGLYAAAGWPRPSASGMPALDIEFVAGMENPAEAIPNAAAWLIAHGWADADI
                     AAIVGGNAARLWEGVR"
     gene            complement(19796..21091)
                     /locus_tag="A37U_RS0116195"
     CDS             complement(19796..21091)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012312.4"
                     /locus_tag="A37U_RS0116195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_020497698.1"
                     /transl_table=11
                     /translation="MAAGLFARPARSQPESRRARAVIAGTIGNFVEWYDWALYGLMFPF
                     FAGQLFPGTDTSSRISALSVLAISFLMRPVGAAVLGAYGDRKGRKSGLAATILLMGGSS
                     LLFAVVPSYAAAGWLAPALVILARFGQGIATGGEYGASSAYLTEWAKPGRRAFTASFQQ
                     VCVGLGVLGASASVTILSALLSDTAMHDWGWRIPFAIGAVAGLVGLWLRSKVAEPEPYQ
                     NLERSGTVERAPLREMLGAHRKAALLLGGLSLSGFVTYYMWLTYLPSYANITTGIDKAS
                     ASLTNTIGLAVFAVVLPFIAILSDRIGRKPTLLIYSVGTVLLAYPLLTGLTGGFGNLLL
                     IGTAGLLLQAFSSATLTPLYAELFPARVRTVGIALPYAVCGALFAGTAPLIMEAFADAH
                     INWAAPVYVIAVALITTVVVWRMPETKDRSLA"
ORIGIN
        1 gaccgagttc gcgggcgagc cccttggtca gcccggcgag cgcggccttg ctcatggcgt
       61 acagcgagaa tccggggaac accactcgtt cggcgacatt gctgccgatg ttgatgatgc
      121 gcccaccgga ggggaggtgc gcggccgcgg ccttggcgat caggaacggg gcgcgcacgt
      181 tcaccgcgac cgtctcgtcg aacaattccc ggccgagttc ctcgacggga gcgacgtgat
      241 agaccccggc gttgttgacc accacgtcga gccggtcgta ttcgtcgagc acccgtcgca
      301 cgagaccggt cgccgcttcc ggatccgagc tctcgcaacg gatcgcgagc gcgcgccgtc
      361 cggtggcctc gatcttcgcg gtcacatccg cggccgctgc ggcgtcacgc cggtaggtga
      421 gcgcgatgtc catcccgtcc tcggcgagcc ggttcgcgat cgccgaaccg atacccctgc
      481 tgccgccggt gatcagggcg actttggttt tctcagtcat accgccatcg tggggcagcg
      541 gcggcggtgt cgctggcgaa gatcggccgt tacgttcggg cgcgcgcgat caggtaggcg
      601 agcaccccga tcacgagcca gcccgccgcg atgagcaggg cgagccggga agccgatgcc
      661 agcagggcga tcgtgagcac ggttccggcg aacgggatga gcagccacgg tcccgcacca
      721 cgccgcttgc cgaaataccg gatggccgag gcgtgcagca gcacgaaggc ggtgagtgcg
      781 ccgacggtga ccatggagga aagcgtgtcc agcccgtccg gttgcagtgc cgcccatacc
      841 gcgatcgccg cggtgcacgc cgcggaaagc aggatcgcgg tgcgcggggt ccgggttttc
      901 gggctcaccg tggccagcca gccgggcagg tgtccctggc tggccatgcc gtacagcagc
      961 cgcccggccg cggcctgggc cacgagcgcg gagaacacgg ggccgatcgc cttgtacacg
     1021 ctcaccgaga tgccgagcca gccgccgatc gcactgtgga tcagcgtgta gaacgcggtg
     1081 ccctggtcct gcgggtgcgc ggcgagctgt tccggggcga ccggggagat cagcgaggcg
     1141 aggtaggtct ggatgacgaa caggacgccc gcgagcccga ggcagaacac caaagccttg
     1201 ccgacctgtt cgggcccgcc ggtgttctcc tcggcgaacc cggcgatcgc gtcgaagccg
     1261 aggaacgaga gcgcggccac cgaggccgca cccagcagcg cgcccatggt gagcccgccg
     1321 gtcccggtca gcggggagaa ccagccgcgc gcgggaccgt gttcggcgag cacgacgatg
     1381 gcgcacacca cgaacacgaa cagcagcacc agcccgaccg cgagcacgat catgccgacc
     1441 cgggcggcga tccgtgcccc ggcgaggttc agcgcggtga acacgcagat cgcgaccccg
     1501 gtggcgagcc aggtcgggat cgccggggcc gtggagtgca gtgcggtccc gctgagcagg
     1561 gcggcgaccg aggggatgaa cagatagtcc agtccggcga gccagcccgc gaagaaaccg
     1621 ggcgccctgc cgagacccgc cgtggcatac gcggagaccg atcccgcgcg cggcacggcg
     1681 gccgacatcc gggcatagga ccaggcggtg aacccgacca cgagcgtggc gacgacgaac
     1741 acgagcgcgc tcgccccatc gcttgccgca tcgagtaccc cgaagatacc gatcggcgcg
     1801 gtcgggccga tgaacagcag cccgtagacg atcaggtcgc gggcggaaag ggtgcggcgc
     1861 aggccgggac tctcggacac agcatcactc cacagtggac tcgagtcgag cctatccagc
     1921 gggagaactg tggaaccatc cgtgcgcaca tcacggcatg atcggcaaag gatgccgaca
     1981 actgcccgga tcagcggcct tgaattgtgg aacaataatg actaagttga gtggcgtggt
     2041 gaacgaggaa cccgtgcccg ccggtgcgca ggtggccgat gcgctacggg tgcgcatcac
     2101 cgagggcggg ctgccgccgg gcacccagct gcgggacacg gcgctggccg cggagttcgg
     2161 gatcgcccgg cacaccctgc gcaatgcctt gcggcagctg gaatacgagg gcctgatcag
     2221 ttaccggatg cacaagggtg cggtggtcaa gaccctgtgc accgaggatg tgcacgagat
     2281 ctaccgggtg cggcggaccc tcgaactggc cgccgtgcag cagagcgcgc tcgccggatc
     2341 cgctgccctg cgcgggctcg aagaacgggt gcgggccgcg gaggtggcgg tcgcgtgcga
     2401 atcgtggaat acggtcggca ccgcgagcct gtggttccat caggcactgg tggagctgct
     2461 cggcagccgc agtatcgacc ggttcttcca gggcatcctc gcgcagctgc gtctcgcgtt
     2521 cgcggtgatg ccggacgagg cgcagtggca gccgccgtgg attccgcggg accgggagat
     2581 ctgcgatctg gtgcgcggcg ggcagcgcgg cgcggcgatc gcggcgaccc gccagtacct
     2641 cgaggactcc gagctcgccg tactcgatgt ggtccgcgcc gatgagatga ccgggaggac
     2701 atgaccgtgg tagccgccgc gtacgaatcc ggggagggcg cgctcgacgt ggaccgggac
     2761 ttctaccgga gcctcgccga gaccaggcac gaactggtgg acgccttcga gatcccgatc
     2821 cggaccggga aagcgtggac cgtcccggaa ggacatctgt gccgactggt cactgtggac
     2881 ggtccgcagg tcggcgatct gaacatctgg aacgccgcgg atccacggga acggctctgg
     2941 gccgcgcgca ccaggcagct gcagcgcgcg cacgtgagca ccttcgagcg gctgtggtcg
     3001 aatctgccgt tcctgcggcc gctggtcacc gtcaccgccg acacgctcgc cggatacgga
     3061 caggacgcgg acggtggccg ggtgcacgat ctgctcggca gccgctgtga tccctatgtg
     3121 aaccggatgc tcaccggcga ggatttcgac tatcactgcc attcgaacct ggtgcgcgcc
     3181 gtgcttccct acgggctgac cgaattcgac gtgcacgatg tgctcaacgt cttccagtgc
     3241 accgggctca acgaggaaga ccgctacttc atgaaagcct gtcccgcgcg accgggcgac
     3301 tacttcgaat tcttcgccga actcgaactg ctctgcgcat tgtccacctg tccgggcggg
     3361 gacctctcgg tgccgatgtg gggcccggac gccggggatc cgctcgaggt gtgccatccc
     3421 atcggtgtcg aggtgtaccg cccggatccc gcgctgctgc gcgactggcg caggccggag
     3481 cgcgccgcct atgcgggcgg gcacggcctg cgcgccccgg cctggccttc ctgagctcgg
     3541 cgttcagccc agcagggacg gcagttccgt cgtgctgctc agccgggcgc gcttgccgag
     3601 catgcgttcg gtgagcaggg tgtgcagttc cggatcggca tcgccgcagg catcggtgag
     3661 cagcacgacc cggtaatccc gatccacggc ctcgatgacc gtggacagca ccactccgct
     3721 cgtcgcgacc ccggcaagca cgagggtgtg cacctcccgt gcgcgcagtt gctcgtccag
     3781 atcggtggtg gagaaggcgc cgatccgggt cttgcgcacc tggatgtcgc cgggctcggg
     3841 ggcgaggcgc tcgtgcacgg cggtggcggg tgcttcggcg tgcatggcgg cgcgccgttc
     3901 gggggtgacc atggcggcca tgatgctgct cggcgggatc cggtcgaagt cctcctcggt
     3961 gaaggcgacc cggacgtagc cgatgtgccc gccgcggtcg cgcatcaggg aaatggcccc
     4021 ggccgcacgc tcgagcaggg cctcggcgtc gggcagggat ccgatgattc cgttctggta
     4081 gtccatcacg agcagcgcac tgtgccgcgg gtcgatggtg tcggtcatga gacagctcct
     4141 cttcagttgg ttgtccggcc gagtttccgg tcggcgaggg tgatcagcag tagcagcccg
     4201 cccatgacga gcaggaaggt cgcgagctgg tgcagcccgc cggtgtcggc gtgctgtccg
     4261 tagaaaccgc cctgtgcggc ggaagcgatg atcgcgccga gatagctgaa ggtgcgcagc
     4321 agcccggccg aggtgccgat gctgtccgga tccgcttggt ggtaaacgga attctgcaga
     4381 gcgaggctca tcagtccctg ggtgatcccg aagatcagtg cgatcgtcac gagcagccag
     4441 atcccgcttt ccggccacag caccagcatc agcgcgcagg cgagaatctg gcagagcgcg
     4501 ccggccccga gtttggcgcg cacctccttg cgccgcccgg tcagcccgga gaccacgacc
     4561 gcggtggcga acaccggcag ctggatgagc ccggcctgcg ccgcggtgag cccacgcccg
     4621 tcctcgagcc attgcgtgta accgtagaga aaagcgtagg agacgatata ggcgagcagg
     4681 gcccgggcgt aggtggccac cagcgggcgg ttcccggcga gcatccgcac atcgatgaac
     4741 ggctcggtcg accgcagttc ccggagtacg aaagcgatcg cggccaccac ggtgatcagt
     4801 ggcagatacc agtcggtcgc cgaggggtgc atcaggaaca gcagcaggga cacgagcatg
     4861 cccgcgaaca gggccatgcc gaggaaatcg aggttcggcc ggttcgtggt tttccgggcg
     4921 gtcgccggga tccggcgcgc cccgagcacg aacgcgagga tcgcgaaggg aatgttcacc
     4981 ccgagggtgg cgcgccagcc gccgagcccg atcagcagtc cgccgagcgg gggaccgatg
     5041 accgcgatgg tctgggtggc catcgcgagc accgtcagaa ctgccgttgg gctgtccttt
     5101 ccggtgcgct ccgcctcgtc ccggatcatc cgcatcgcgg ccggataacc cgcgcaggtg
     5161 ccgaaaccga gcaacacccg cgccacgatc agcacgccga gatcgggggc gagcatgccg
     5221 agtatcccgg cgagaccgac gagcacgctg gcgccgagga acagccgccg cggcccgtgg
     5281 acatcgatca gtttcccggc gaccggctgg ccgaccgcgg tcgccaggta cagcgccgag
     5341 acgagccagg cggtcgcggt cggcggtgcg ccgaaggcgg ccccgatcgg taccagggac
     5401 accgagatga tcgaggaatt gaccgggttg aggatcgcgc ccgagatcat cggagcgagc
     5461 agcttgcggt cgaaaccctc gctcagtgcc gcgaaccgct cgcgcggttt cactgctgga
     5521 ccacgcggtc cagcagggcg atggcctcga tgatcgttgc gcgttcggcc gccgtgtagc
     5581 gctcctggat cgacctggcc agccattcct cccggctcgc ccgcgcgccg tgtccctgct
     5641 tccggccggc cgcggtcagc gtgatcacct ggcgacgtcc gtccccggga tcgggcgcgc
     5701 gctcgatcag gccgtgtttc tccagggcgg tcagggtggt ggccatcgac tgcggccgca
     5761 cccgttccgc gccggcgagc acactcgccg aggacggtcc gtccttcacc agccgggcga
     5821 gcacggaggt ctgtgaggcg ttcagatcct cggtcgccgc ggaatccagc aggcggcggc
     5881 gcaaccggct gaagagcact cgcaggtcct gcgctgcctt ggcggcttcg gtggagatct
     5941 ctgccatatt cgacagccta aactaatcag cctggactgt cgaattgttc agtcgagctc
     6001 gtgcacgagt tcgatggccc ggccgagggt gtcgagtttc tcggtcagtg actcgcccgc
     6061 cggatagagg cgcaccgtgt cgatcccggt gtcccgccag gtgcgcaatc gttcgcggac
     6121 catggcctcg gtgccgatca gggtggtggc gagcaccatc tcgtccggga ccagttcggc
     6181 cgcgccggtg cggtcacccg cctgccagcg ggcgctgacc tcggcggcga cctcggccca
     6241 gccctgacgg ccgtaggcgc ggttgtagaa gttggtgtcc gcggtgccca ttccgccgag
     6301 gctgaacgcg agcccggtct tgcgtgcggc gagcatcccg ggcagcgcgt ccgcatcggg
     6361 cgcgaaggcc acctcggcgc cctggcacag gtccagatcc gcgcgggtcc gcccggaatc
     6421 gcgcagtccg tggtcgaggt gtgcaaggta ggcatcggca ccctcgggga cgaaactggt
     6481 gccgagccag ccgtccgcga gctccccggt cagccgcagc atggcggggg agagcgcggc
     6541 gagatagacc gggatcgggt gttccgctcg cgcggagagc cgcatcggcc gggtttccga
     6601 gccgggaagc ggaatgcggc cgggcaccga gatcttctcc ccggaacggg cctggcgcag
     6661 gacttccacg gtctggcgca tccgggaaag cgggcgctgg aacggaactc cgtgcagtcc
     6721 ctcgatcacc tgcggcccgg aggcgccgag cccgagcagg aaccggcccc cggacaggtt
     6781 cgccagcgtg atcgcggcct gcgcggtcgc caccggggag cgcacgccga gctgcatgat
     6841 gccggagccg agcagcatcc gttcggtgcg ggcggcgtag taaccgagcg cggaaggggc
     6901 atccgaaccc caggcttcgg cgacccagca cacgtcgagg cccagtttct ccgcctcgac
     6961 gacgaactcc ccggtctgtt tccagtccgg cccgcccgag gcctcgacgg tggtcgcggt
     7021 gcgcatcacg cctcggcggt ggtcttgacg tggtccagcg tgtcggtcat gaactgctcg
     7081 acatcgcgca gccggcggcg cagaatccgg tcctccttct ccggcatgcg cgcgatcgcg
     7141 agggtcagcc cggacgggcc cgggcccagc tgggcgtact ggcgcagccg cgttccatcg
     7201 ttctccggtt cgagccggaa ccgccacacc gcgttggggt tgtccggatc gctgaccgcc
     7261 caggcgaaca cctgtcccgg aatgcattcg atgacctggg aatccgtgga ccagtcgccg
     7321 aggatgtcgt tcctgttgtg cccgcggaac cgcgcgccga gtgcgggccc gctcgccccg
     7381 tccagccatt ccgcggcctg gagttcggtg ctcatcgcgg gcatcgcggt cacatccgag
     7441 accagttccc atactcgttc gggtgcggcg gcgatccacc ggtccacctc gacactcggt
     7501 gcctcggcga gacgtaatcc cgttgactcc attggcggcc tccctgctcg ccactaagtt
     7561 gcatgatgaa actcagcatg tcaagagaac cttttccgta ccgaggtgcg gtcggcgagc
     7621 gcttcgggga agccgggacc catccgtgcg cgggtgttcc cggcgcgcat cggctccccg
     7681 caggcggcgc acacgacctc ggcgtggctg tccgcgccgc atgcgtggtg cagtaacacc
     7741 ggaggaccct gctccccggc gagccagcga tctccccagc gcgccatcgc cgcgagcacg
     7801 ccgaagaaat ccctgccctg ttcggtgagc aggtactcgt ggcgcatcgg ttcgcgctga
     7861 taggcccgct tctccagcag cccgtccgcg accagcctgc gcagccgttc ggtgagcgta
     7921 ttgcgggcga tgcccagttc gcgctggaat tcgtcgaagc ggcgcagccc gtagaagcac
     7981 tcgcgcagca cgagcggcgc ccatcggtcc ccgagcaggt ccacggtccg cgcgatcgag
     8041 cacggccagt cggcgaacga ggtgtgtttc atgccggcca gggtacggcg ctcagccgag
     8101 gcgttcgcga tagttggcga cgcgttcccg gttgccgcac acccgcgagg aacaccagcg
     8161 ccgcctgcgc ccgcgggaat ggtccaggta gaccagatcg cagtcgccgc ccgcgcattc
     8221 gcgcagatac tgccgttcgc tgccgctgag cagttcgatg gcatccctgg cgacaaggga
     8281 aagcagcccg gcgagggtga ccggttcgcg cagccggacg gtgcgcgcat cggtgcgcag
     8341 ccggggaatc ggcggggtct gcccggccag ttcgttgagc gcgcgcacac gcgagacggg
     8401 gacggttcgc ccgtgcacgg tgtcctgcac gatccggtgc agcagcgtgc gcacccggtc
     8461 gacctgcgcg aaccagtccg gcccgatcgc gatcggctga tcggcgggca gtaacccggt
     8521 tccggtgaac caggcgtgca gccggtccgg cccgttgagc cgttccaccg gatgctcgct
     8581 gagccgggat ccgacggtgg ccagcagatc gaggcagacc cggccggtgt cgaagcgcag
     8641 ctgctcgctt gccaaggtga tcacatccct tcgggggaat tatgccgtcc cgggctgacc
     8701 agggtcgcga gcaggcagca cgcaccggcg cccgcccaga ccgccgccca ggacgcgccg
     8761 tccgcgagca ccgggatcag caccggggcg aggaaacccg cggcgaacac ggtggtgttc
     8821 tccaggccga gcgcggtccc ggcccgcctg gttcccgcca tacgcgcgat ctcggtgtag
     8881 gccacgccgt gccaagccga agcgagcaac ccacctgccg cgagcgcggc cacggtgagc
     8941 cccacgggcg cctcggtgag caccgcagcc ccggcgaagg ccaccgtgct cagtccggcg
     9001 accgccttga tgtacccgcg cctgttcccg tgccgatcgg tgtatccgcc gctccatacc
     9061 cgcgcggccg ccccgcccag ctgcacgatc agcagcgtca ccgtgccgag cgcgagatgc
     9121 gtatgccgtt ggctgacaag gaaaaccgag gcgaaggtgg tcaccgcgaa ctgcgggacc
     9181 gaaagcagcc cgctcgccga tgccagccgc cacaccgccc ggctgcgcag cggggaaccg
     9241 ccgatgccgc gcggttgcgc ggtggactcg gccggttcgt gcagccaggc gaaggccgcg
     9301 gccgccgagg cgaagcagaa cagggcgagc gcgccgaaca ccgcgcggaa ccccagatca
     9361 ccggccagta ccggaagcag cgccgcaccg agcgcaccac ccgcggggat cgcggtctgc
     9421 cggatgctca tcgcgaatcc gcggcgatca tcgggaaacc aggccatgac cgcgcggccg
     9481 ctcgaaccgt tcaccgaacc gccgagtacc ccgaccagta agagcgcggc cgcgaacacc
     9541 aatgccggag cccccggggt caggacgacc gccagcagcg ccagtagggc gccggtaccg
     9601 agcaggccgg tgagcagggt tcgccggtca ccgagccggt cggtcaccat tccccagggc
     9661 acctcggaga tcgcgatgcc gagtaggatc gcgccgagca ccaggccgag ttgtcccgcg
     9721 ctgaagtgat acctcccgcg cagcagtggt ccggtggcgg ggattccggc gaaggcggcc
     9781 gagaaactgg cctgtgcggc caccccgatg ccgaggatca gccagcgatg gtgcgcgccg
     9841 aatccgcgga gcgcagggtt catgtaatga gtcagagtca tagctaatga ctctagggtg
     9901 ttacgttcga gcgacgcaag taccgatcgg taccaagtcg ccggaacgaa attcgacgag
     9961 gtggctgtgc gcacgagccg gggcgcggta ggaaggaacg gtgaccgatg actttcgcag
    10021 cgccgcgaac accctgttgc acgagtccgc cgcggatccc tgggcctggt tgaccccttc
    10081 ggtgtacgag tgtgcccgct tggtggcgga cgcaccgtgg ctcggcgggc atgccgagcg
    10141 gttgcgccac ctgtgccgga cggtgaccgc cgacggcacc tgggggcagg acggattcgc
    10201 gttcaacgcc acgctttcgg ccaccgaggc gctgctcgcg gttgcccagc ggcgggaacc
    10261 cgcggatgag gtcatcgagc gcggcaaggc ccgcgcggtg gccgggcagg gcctgcgtgc
    10321 gctgcgcgac tggctggcac ccggcgggcg ctacgcggcc gggccaccgg cgacgatcag
    10381 cgtggaactg atcgtgccga tgctggtgga ccggatcaac acgcgcctgg cggccgcggg
    10441 ggaaccggag ctgccgatgc ccgcggggtg tgccaccgaa cggctggccg cgatccgggc
    10501 ggacgccgcc gcgggccggg aactgcccgc ggacatctgg catgcctggg agatcgccac
    10561 cccggtcgat tcggcgcacc cctacgcggg ttcggtgagc tgttcggcgg ccggaacggc
    10621 ggggtggctg cgcaccgcat cggatccggg cagcccggcc gcgcggttcc tcgaggagct
    10681 gcagcgccac gggaacggcc tggtgccggt ggccgcgccg atcgactact tcgagcacgc
    10741 ctggatgctg aacaccttcg tctggcaccg ggttccgcac gactgcccgg agcggatcct
    10801 ggaccggctc gagtccgaac tgggcccgca cgggatcgcg ggcggcaggg atctcaccgt
    10861 ggacggggac gacaccgccg cggtggtgaa cgcgctgctc tgtcatgggc gcacggccgg
    10921 actggacggg ctgctgacct actgggccga ggaccatttc cagatctatc ccggcgaatc
    10981 gatcgcttca ccggccacga acgggcacac ggtgagcctg ctgcaccgct atctcgccga
    11041 gcgccccgag cacggcgagc gctacggtcc ggtgctgcgg cgcaataccg aatggctgct
    11101 cgaccagcag cgcgccgatg gcagctggtt cgatttctgg cacgtttccc cgtactacgc
    11161 cacggtgtgc gcggtcgagg cgctttccgc ggtggacggc gaaccggcga aggccgccgc
    11221 gcggcgcgcc aggcgctggg tgctcgatac caggcatccc ggcggcggct ggggcgtgcg
    11281 ctgggtgacc atggaggaga ccgcgtacgc cgcactgatt ctgcgcggta gcaccgaaac
    11341 cggcgtggcc gaggcgctca cctgcgcgga gccggtgctg cgcgatgggg tggtggatgc
    11401 cgggatcacc ccgctgtggc tggtgaagga ctactttgcc ccgatccggg tggtcgccgc
    11461 cgcggtgctg gccgcgcggc aggccatcct gaccggtcag cgcggggctt gaagcagcac
    11521 cggcagagct tcgagccccc gcatcagggt gctgtgccgc caggtcagct cgccaggggc
    11581 caccgcgagc cggatctccg ggaaccgctc gagcagcatg ccgaacgcga tttccgcttg
    11641 tgccctggcc agctgcgcgc cgatgcagta gtgcaccccg tgcccgaaag cgagatgacc
    11701 cgtggtggcc cggtcgaggt caagttcccg cggatcggtg aaccgctgcg cgtcccggtt
    11761 cgccgagagc agggcgacca ccacgaactc acccgcggga atgctcgtct caccgatcgg
    11821 cacatcctcg gtggtgaacc ggaatgtggc gaagttgacc ggcccgtcgt agcgcaggaa
    11881 ttcctcgatt gcggcgggca gtccggccgg atcggcgcgc agcgcggcga gctggtccgg
    11941 attgcgcagc agggcgaggg tgccgttgcc gatcaggttg accatggtct cgtgcccgcc
    12001 caccagcagt acgaacacca tggcgcgcag ttcaccctcg tcgagccgat cacctgcctc
    12061 ccgcgcctcg accagcgcgg agagcagatc ctgtccgggg gtgagctgct tctgcgcgat
    12121 cagcgcgtcc agatagccga ccatggcctc ggaggcagcc gccagttcct gcgcgccgac
    12181 cccggtgttg agcagtgtcg cggtccagga acggaaatcg gcccggtcgc tctcgggcac
    12241 gccgagcagt tcgcagatca ccgtgatcgg cagcggatag gcgaagccgt gcaccaggtc
    12301 caccacctcg ccacggggca aggcgtccag cagttccccg gcgatctcgg tgattcgcgg
    12361 gcgcagctcg gcgaccctgc ggctggtgaa cgtcgcaccg accagtttgc gcagcctggt
    12421 gtggtccggc ggatcggtgt tgagcatgtg cgaattgagg aactcggtga tcaccggggt
    12481 cgagttcgtc tcctccgcct gccgcgcgga cagttcctgc tggcgtacgg aatccttgcg
    12541 cagccgggga tccgccagtg cggcccgggc gtcggcatag cggctgacga tccacacccg
    12601 cagcccgtgc ggcagcagcg cgggggcgac cggctgctcg gcgcgcagcc ggtcgtagag
    12661 ctgatagggg tcctgcagga attgttcgcc gagccggatc ggttcggtca cggggccacc
    12721 tccctacgtt gggcttgcag ggcacgcctg ccgggttcgc agagctcacg cagccggtcg
    12781 agctcctccg cgggaagggc ggccgccccg ccgacccggt tccggtcgag cagtcgttcg
    12841 gcggtggcca gccagctggg atccggttcg acatccagga aagcggcgag ccgcgcgagt
    12901 tctgcgcgtg ggtgcgcgac caggtcctcg tatccgatcg tgcaccgccg ttcggccggt
    12961 agctcggcga ggccggtgac cgcgtcccgg atctgcgcgg tccacagctc ggcgaattcg
    13021 gccagcggga tcggttgttc gagcacggcc gggtcgaacc ggtccggcag caccttggcc
    13081 agttccggcg ggagcgcggc cacatcggcg gggcgcagct ccggaatggc gcgcgccccg
    13141 gtcagcgcct tgatccggtt ctcgagcacc accaggcgga atcccgggtg cctgctcatg
    13201 gagagcgcgc agtccggccc ctcccggaac atgtgcacca gccgcgcggc agggaagcgg
    13261 tcggcgaggg tgccgatcca ctgcagcgag aacccggagc gctccaccac ggcggtgcgc
    13321 ccgaaacgcc ggcccagcag ggcgaacagg gccgcgtagt gctcggtgac cgggcgggcg
    13381 ggccagctcg gtatctgctc ggcgagctcg tcgaacaggg cgtcgggttc ctcgctcagg
    13441 tgcggcagcg ccatcatcgc gatcgccgga atgccggtct ccggactgaa tcggccggga
    13501 tcccgcggat acaggaactc cggaacccgg ctgcgttcgc gcgccatcgc gtcgaagaac
    13561 gggttcggtt cggcgagcag ccgccagaat tcggccccgg tcaggggtcc agggggaaag
    13621 gttcccggcg ccagcgaggc gaacagttcg ttgaggctga gcacgtccgg atgcccggcg
    13681 agcacccggg acagcgcggt ggatccacag cgcccggtgc ccaccacgaa gttcagggag
    13741 cgcatggcga ggactccgtc atggctacct ttctaccgtc cggcatccgc tttttggtga
    13801 gacagccgga tatttgtgtg tagtgtgcgg gatcagaccg ctaccgctgg ggaggcgccg
    13861 gtgccgaccg attccgaaca cgcagagcga cagatccggt tgttgtccgg gcaggtcgaa
    13921 cagaccatgg cggaactggt cgccgaatac accagcgaac acggtcagtt gcgcgccatc
    13981 gtgcccaccg tggtccggga agcccgtgcg gaccggcacg agttcgccct tcccctgctc
    14041 gtgcacgggg cggagaccgg tgaccccgcc gcagcggtgc cgatcgcggc cgtgcacgca
    14101 ctgtggtggc gcgcggcgaa catcatcgac gacctcgccg atgaccaggc gggtgaggcg
    14161 gcgcgccgga tcggaccggg tgccaccatg ctggtcgcgt tcaactgggc gtatgtgctg
    14221 cccgcgcggg tcaccagcgc gctgccggtt gccgaaccgg tccgcagcgc gctcaccacc
    14281 gagttcctgc agtcctgcac cgccgcgacc gaagggcagc tcgccgacct gttcaccgaa
    14341 cccggagagc tctcgcatga tcaggtgctg cgtacctacc tgaacaagag cagcgcaccg
    14401 tacgtgatgg cgagcgcgat ggctgccagg accgcgggcg ccgacgacgc gcgcaccgag
    14461 gggtggcggc ggttcggccg caacctcggg ttgctcggac agttccgtaa cgatcaggag
    14521 gatctgcagt ccggacggat ggaagacctc gccaacgcca cccccacctt ccacctcgtc
    14581 tcactgctga actccggcca cggtgcccgc cgcgaacgcg tcctcgcgct gctgcggcgc
    14641 gcgcgaacgg acacgcacgc ccgggaggaa ctgctggagc ggatgctcga cccggaggtg
    14701 gtgcggccct atctcgcgca catcgagggg gtccggcacg aggccgagca ggtcctcgat
    14761 gaactcagcc tcgacgagct cggcggctcc ggctgtttcg tggccgcgct gcgcggacgg
    14821 gtgcgcgccg cggcgactcc gtgtgaactg ctggcgggtg tggcgaaccc ggcggaagcg
    14881 agctgagccg gaatccgtgg ccggttacgg catcagccgg gtgtgctggt gtattcgcgt
    14941 ccggtcgggg tggtgatggt gagccgcgcg gtggtggggt cgagttggtg tttccagtcg
    15001 ggcatgcgtt tcagtttgtg gttgattcgg cagaggcctt ggaggttggc gggatcggtg
    15061 gtgccgtggt ctcggtgcca ttgttcgacg tggtcgatct cgacgatggg tcgcctgcat
    15121 cccggagcgc ggcaatggcg gtcgcggatg tggacgaaat cgcgctggcg ccgggtcggc
    15181 cggtaacgct tgcgccccag gccttgtacc acgccggtgt ccgggtcggt gaggactttg
    15241 cgcaccacgt tgttcgggtc ggcgagcagt tgacgggcga cgtgcgcggg gatttcaccc
    15301 attccgtcga cgattgcggt gctgttgttc agctgtagcg cggtgccgag gggaacgtgc
    15361 acgttgacga ccgtgtgtac cggtgggtga tcgtcaccgc gtccgaggag taggtcggtg
    15421 aacacgtccg cgcggatttg ttcctgggtg cgcgtatctc cgcgttgtct gatcgcccgt
    15481 gcgagatctc ggatgcgtgt ttcgcatgcg tgggagtctt cggcggggat ccgggcgaac
    15541 accgtcccgg tgccatcctc ctcatcttgg aacgacacat accgggcggc acgcgcttgc
    15601 gcgagccgct tctgtttcgc tgtcgggtcc agtgagtccg ctatccgccg caggtaggcg
    15661 cgccagtcgt gcggcaggcc ctgttcgcgt aagcgttgcg cgatccgccg gtccgcgatc
    15721 gcggccagtt ccggggtgag tgggcgcagt acttcggtgg ctttcgacgc gagaaacgaa
    15781 tccagcaacc cctcactcat gcaggacagt aattcgggaa atcgttcgtg catctcgacc
    15841 gacaattcga ctgtaccgat cgccttaccc cgataacaac accaagcgag gcgtagttcc
    15901 tcgatcaccg aatcccgcgc cagctcctcc ccgaaccgtg ccgcctgcga gcgccatagt
    15961 tggtgcacgt caatcaggat ccgatgatcc agccgtgcct gctcggtccg ataggaacac
    16021 gtggattcca ccaacgcgtc ctcgaattca cgactcccca gtccgttcat gctcccaatt
    16081 ctagcacaat tcccgtaagc tgtgtccgtt cattttgagc gtgcacggcc atccgcagat
    16141 cccggctgat ccgggctgag gcgcgctcag cgtgctcgga cgaaccgttc cagcagctcg
    16201 acggcgatcg gcaggctgcg ctcgtcgatg tcgaagcggc cgtggtggtg cggcgccgga
    16261 ttggctgccc ccacaagaaa gtatgccccg gtcccgccct gttcgcggac cgcgtcgagc
    16321 agcagggtgg cgtcgtcgct cgcggacatc ggtgcttcgg caaggcattc gcgcacgccc
    16381 gcggtggcct gtgcggccgc ggtgatcccc gcgcacaccg cctcgtcgtg cacggctgcg
    16441 gtggctttcc cggtctcggc gatttccagc tcgacgccgt gcatgtgcgc ggcgccctcc
    16501 aagatcgccc gcgcgcgctc gatcagctcg gcacaggccg cggtggtctc ggcgcgcagt
    16561 tccatgccga gttcggcgtg ttcgggcacg atgttggcgg cggtccccgc gcgcagggtg
    16621 ccgacgttga cccgggtcgc gatgcccggg atcggtggca tggcatgcaa ggcgttcgcc
    16681 gcgtgagttg cggcgagcag ggcgttacgg ccctcgttgg gggcgagcgc ggcatgcgcg
    16741 gcgcgcccgg tgagccgcac ccgcagtttc accgtggcga gcatgccccg cgcggccgcg
    16801 gcgacggtgc ccacttccag gcccagcccc agatgcaggg ctagtatcgt gccgattccg
    16861 gtgcacgccc cggcttcgac gagtgcacgg gccccgcgca cgccttcctc cgcgggctgg
    16921 aacaacagcc gcacggtgcc cgggaagtcg ggatctgcgg cgagcctgct gcccagttcc
    16981 accccgatcg cggtgtgccc gtcgtgcccg caggcgtgca tcacgccctc ccgcgtcgag
    17041 gcgaacccct ctgccgcggg gaaatgcgcc gcctcgcctg cttcggtgac cgggagcgcg
    17101 tccatatcga agcggatccc gagcaccggc cctggacggt tgccgtgcac ttcggcgagg
    17161 attccggtgc ggccaccgga aagcgtgtcg atcagctccg gtgcgacacc ctgaacagcg
    17221 gcccgttcgc gagcggcggc gagctcggcc ggatcgggca gcccggcaag tccctcgacc
    17281 acgcacacct gctcgccgta gcacggttca atgcccgccg cgcgcagttc cccgatcacc
    17341 gtggccgcag tgacgatctc ggtgaacccg gtctccggat aggcgtgcaa ccgcctgcgc
    17401 agtgcccgta gttcggtcat cgcgggtaat ccggtgccct ggtggcgaaa tcctgccgta
    17461 cgtgcgcgag gaaaaccgga tcggcgagca gatcggcgcc cgcacaggcc agtgctcgtg
    17521 ccatcgcgaa catcgaggtg tgcgccgaat cggtcgccgc gtactcggtc atcgcccggg
    17581 aatggctcgc cgttccctcc ggcatgatcg ccagatacgg gtggatggcg ggcagttcca
    17641 ggctcacgtt cccgatgtcc gaggaaccgg tgcccccgcg aagcaccggt tcggagaccg
    17701 ggatcccttg accgcgaagg taatcggcga cccggtaggc gagcggatgg ttgttcttgc
    17761 gctcggcgta gagcggtccg taggtcagct ccaccttggt cccggtcgcc gcggccgtac
    17821 cgtgcgcggc ctcgttgaag cgctcgacta gttccacaac ggactcgctg gagatgtccc
    17881 ggatctggaa tttcccgctg gcgtactcgg gaacgacgtt cggcgcctgc ccgccctcgg
    17941 tgatgacccc gtgcatccgc accgtctccg ggacgaactg gcgcatcgtg tccatggcca
    18001 cgaacagctg gatgagcgcg gcgagcgcac tgcgcccgtc ctgcggggaa cccgcggcgt
    18061 gcgcggcgat cccgtggtat tccacggtga tcgactgcgc ggcggtggcg tgccggatcg
    18121 gcacggtgcg atcgccgggg tggaacatca gcgcggcatc gatatccgcg aacacaccgg
    18181 cctcgagctc ggtgatcttg ccgcccgcac cttcctctcc gggagtgccg atcacgcaga
    18241 cggtcccgtc cagaccggcg gcctgccggg ctcgcgcggc cgcgatcccc gcggccaggc
    18301 cgccggtggc gatcagattg tgcccgcagc cgtggccgat gtccgggagc gcgtcgtact
    18361 cgcacaggaa ggcgatgcgc ggggaaccgg atccggactc ggcgcggaac gcggtcggca
    18421 gctccgcgat cccgcgcgtg acctggaatc cgtgttcctc gagcagcccg gtcaaccggc
    18481 ccgccgcgta cttctcggcg agcgcgagct cgggattggc gtgcagatcc aagctcagtt
    18541 cggtgagcgc tttccggttg tcctcgatgc tcgcatcgat ggcggtgtgc gccgtggcgt
    18601 tcaccggact ccttcccata ggcgtgcggc attgccgccg acgatcgcgg cgatatcggc
    18661 atcggcccag ccgtgtgcga tcagccaggc tgccgcgttc gggatcgcct cggccgggtt
    18721 ctccattccg gcgacgaatt cgatgtccag cgcgggcatt ccgctcgccg aggggcgtgg
    18781 ccagcctgcg gcagcgtaga gcccgaggtg gtcgccgaag aaggtatccg ggccgagtgc
    18841 gacgtgctcg atgccgatca gttcggcgca gtattcgagg tggtgcatca cgtcgtcgag
    18901 gtcgtggtca ccgctgctcg ccctgctgcg ggtgctgccc ggcgcggcct cgatcccgat
    18961 caggccaccg gtcgaggcga ccgcgcgcag cacctcgtcc ggtttcatcc gcggggtcgg
    19021 ccacaccgtg cgcgcgcccg cgtggctgat caccagggga cgggtggcca gccgtgccgc
    19081 ctcgatgctc gaccgatccc cgacgtgcgc gaggtccacg agcatgccga gctcttccat
    19141 ggcgcgcacc gcgcccctgc cgaccgggct cagaccggga tccggatcct ggccgagccc
    19201 accggcgagc gcggtaccgg tgttgtaagc cagcccggca caccggattc ccgcgccgta
    19261 caaggcatcg aggccgcgca gctcggtacc gatcggcccg aggtcctcca gtgcaccgag
    19321 tacggtggtg tcggacgtcg cagcgccgct gttctgctgc gcggtcaccg cggttccgaa
    19381 cgcgaccgcc tcgtccaggg ttccgccggc gagcttgctg gcgaacaccg tggacagtcc
    19441 ggtctcgccg aggaacacct gcccggaatc ggcgaaccga atccagctgc gctcattgag
    19501 cggatcgggc agccgcacgg ggtgatcgtg cagcgaaacc gttggcccgg cgaggatgtc
    19561 ggccagccgt tcgcgctgcc cgctgctcag ctccggggcc ggggaagcca cccggtcgcg
    19621 atcggtggcc agcgggacga ccggttgcgg cggaacggat ccttggctca tgacactccc
    19681 aacctgtcgg ggcacgctgt cggaggggct cagcagccga ctcatgccct cgctccctgg
    19741 gggagctcgg tgcttcgccg aggacgctgt atcgatgatt cgctcgcaag ctcgctcatg
    19801 ccaggctcct gtccttggtc tcgggcattc gccacaccac gaccgtggtg atcagcgcga
    19861 cggcgatcac gtacaccggg gcggcccagt tgatgtgcgc gtccgcgaag gcctccatga
    19921 tcagcggggc ggtcccggcg aacagcgccc cgcagacggc atacggcagc gcgatcccga
    19981 ccgtgcgcac ccgcgcgggg aacagctcgg cgtacagcgg ggtgagtgtg gcgctgctga
    20041 acgcctgcag caacagtccc gcggtgccga tcagcaacag attcccgaac ccgccggtca
    20101 gcccggtcag cagcggatag gcgagcagca cggtaccgac ggaatagatc agcagggtgg
    20161 gtttgcgccc gatccggtcg gagaggatcg cgatgaacgg cagcacgacg gcgaacacgg
    20221 cgagcccgat ggtattggtc agcgaggccg atgccttgtc gattccggtg gtgatgttgg
    20281 cgtaggaggg cagataggtc agccacatgt agtaggtgac gaatccggaa agggagagcc
    20341 cgccgagcag cagcgcggcc ttgcggtgcg cgcccagcat ctcgcgcagc ggggcgcgct
    20401 ccacggttcc gctgcgttcc aggttctggt acggctccgg ctcggcgacc ttggaccgca
    20461 gccacagccc gaccagcccg gcgaccgcgc cgatcgcgaa cgggatgcgc cagccccagt
    20521 cgtgcatcgc ggtatcggag agcagtgcgg aaaggatggt caccgaggcc gaggcgccga
    20581 gcaccccgag cccgacgcac acctgctgga aggaggcggt gaacgcgcgc ctgcccggtt
    20641 tcgcccactc ggtcagatag gcggaggagg cgccgtattc cccgccggtc gcgatgccct
    20701 ggccgaacct ggccaggatc accagcgcgg gggcgagcca gcccgcggcc gcatagctgg
    20761 gcacgaccgc gaacagcagg ctcgagccgc ccatcagcag gatcgtcgcc gccagcccgg
    20821 atttgcggcc tttgcggtcc ccataggccc cgagcaccgc ggcgcccacc gggcgcatca
    20881 ggaacgagat cgcgagtacc gagagcgccg agatccgcga ggatgtgtcg gttccgggga
    20941 acaactggcc cgcgaagaac gggaacatca gcccatagag cgcccagtcg taccactcca
    21001 cgaaatttcc gatcgtgccc gcgataaccg cgcgtgcacg cctcgattcc ggttgcgacc
    21061 gggcgggccg tgcgaagagt ccggccgcca tcgttcctcc tcggttggtc ttgcggactg
    21121 gccatgagca tgcgctaatg tgggtgtaca tcgccatagt cgaaatcaca tcgggaaaga
    21181 tcgactattt gagttcaatg attgagcgga agcgggcaac tcttgggtga gcgagaacga
    21241 cccgccgacc cggtggaccg gcgcgtcgcg gccgcgctcg tgctgcatcc gcgggcgagc
    21301 tgggggctga tcgcgcaggt gctcggcatt ccggaatcga ccgtcgcgcg ccgtggcgcg
    21361 cgactgtgct cacgcggcgt ggtcaaggta ctcggcaccc tggacgtgat cgctgccggg
    21421 cggggcaccc cggtgctgat gcgggtctcc tgcaccccgg gcaccgcgcc gacggtggcc
    21481 gccgagctgg ccggacgctc cgaggtgtgg at
//
