LOCUS       NZ_KB905386            20884 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Sciscionella marina DSM 45152 A37UDRAFT_scaffold_14.15, whole genome
            shotgun sequence.
ACCESSION   NZ_KB905386
VERSION     NZ_KB905386.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Sciscionella marina DSM 45152
  ORGANISM  Sciscionella marina DSM 45152
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Sciscionella.
REFERENCE   1  (bases 1 to 127413)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Sciscionella marina DSM 45152
            collection_date                   :: SEP 2006
            lat_lon                           :: Missing
            depth                             :: 516 m
            alt_elev                          :: Missing
            country                           :: China
            num_replicons                     :: Missing
            ref_biomaterial                   :: DSM 45152
            biotic_relationship               :: Free living
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: 19196758
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Sand; Sediment; Marine; Aquatic
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi11892
            Current Finishing Status          :: Level 2: High-Quality Draft
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2012
            Isolation Site :: Marine sand sediment at a depth of about 500 m,
            the northern South China Sea
            Cell Shape                        :: Rod-shaped
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28 C
            pH                                :: 7
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000379465.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 01:37:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,209
            CDSs (total)                      :: 8,146
            Genes (coding)                    :: 7,961
            CDSs (with protein)               :: 7,961
            Genes (RNA)                       :: 63
            rRNAs                             :: 4, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 185
            CDSs (without protein)            :: 185
            Pseudo Genes (ambiguous residues) :: 1 of 185
            Pseudo Genes (frameshifted)       :: 52 of 185
            Pseudo Genes (incomplete)         :: 155 of 185
            Pseudo Genes (internal stop)      :: 15 of 185
            Pseudo Genes (multiple problems)  :: 34 of 185
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:59:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 20884
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB905386.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405877
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Nikos  Kyrpides (nckyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-PGF and JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20884
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..20884
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20884
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6613:10884](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6614..10884
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            <1..807
                     /locus_tag="A37U_RS48285"
     CDS             <1..807
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020500008.1"
                     /locus_tag="A37U_RS48285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphotransferase"
                     /protein_id="WP_020497161.1"
                     /sec_met_domain="APH (E-value: 1.7e-10, bitscore: 34.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RIGDCTTMLAMEEHEIVGRGSMDRLWIVGETVRRERGAHSDTVAT
                     LLTHLERRGYPYSPRYRGIDEQGRDVLTRLPGVPVPTLRGDDQLREVGGAIATFAEAVR
                     DFRAPPGALWRNPEDWPLHGDTVIHNDIAPWNMLERDQRLCGLVDFDSARPGRAIEDVA
                     YAAWHMTPLHDELMGDGAAPPALAERPRRLRIFADACGLDSQQRCRLLDEVARVQINQA
                     ARVAAGALGPRADTARHWDSGRFTVNIARSLLWLDHHRDHLQQTLT"
     gene            1133..1369
                     /locus_tag="A37U_RS51475"
     CDS             1133..1369
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A37U_RS51475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_169526861.1"
                     /transl_table=11
                     /translation="MALTLASTAGAAPPPVYRSYQDCQVAGQNAVGAAGGPGNLSYQCQ
                     EIPGVPAGVAGCPPNAGPSGCIGDYYELLTSSP"
     gene            complement(1527..2111)
                     /locus_tag="A37U_RS0113440"
     CDS             complement(1527..2111)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025052.4"
                     /locus_tag="A37U_RS0113440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_020497163.1"
                     /transl_table=11
                     /translation="MATRAERKREDVAGMIGVVAVLILLVGLPGSGKTTMARRLAGERA
                     ALRLSPDEWMLPLFGAPDLDGKRDVLEGRLISVALRLLALDTSVVLDFGCWSRDERAAL
                     RWLTNQAGGTFELVYLPVDRATQRQRIAQRHHETRCASMVLTTAEIDSYEQIFDVPNAS
                     ELAGNYPSAPPQGWTDWRAWAIQRWPSLTAT"
     misc_feature    complement(1971..1973)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2166..2648)
                     /locus_tag="A37U_RS0113445"
     CDS             complement(2166..2648)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="A37U_RS0113445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_020497164.1"
                     /transl_table=11
                     /translation="MATLRDYQVGDEPAVVALGLRAWEPVFAAIEELLGDELFSRLRGD
                     WRAGQAQAVRNVLANPGQQVWVAEQPDETVIGFVAARLEHATGVGEISMLAVAPSAQRQ
                     GLATALTDRATDWLQRSGMRVAMVETGGDPAHAPARRVYQNSGYTALPAVRFFELL"
     misc_feature    complement(2535..2537)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2648..3016)
                     /locus_tag="A37U_RS48290"
     CDS             complement(2648..3016)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013098.4"
                     /locus_tag="A37U_RS48290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_020497165.1"
                     /transl_table=11
                     /translation="MGNSYWPLTSGALDLENGHGTPAGDLGIWRRDHELIPERFRQAPA
                     GTVLSFVVDDVDAVYAEAQRRQLSVVAEPRNLFYGQRQLLLTDPNGALVDVSTPVGMSG
                     EFAATLVQDGQTIRQQHS"
     gene            complement(3364..3597)
                     /locus_tag="A37U_RS52890"
     CDS             complement(3364..3597)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A37U_RS52890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_205622923.1"
                     /transl_table=11
                     /translation="MMWPRPGRVFAAARSHSFAQLAEAVDAAFARWDLAHLHMFTLAEG
                     TNLCRARDWDGELPDEALDSAATKLSRLNLGE"
     misc_feature    3623..3641
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.38"
                     /tool="antismash"
     misc_feature    4046..4059
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.46"
                     /tool="antismash"
     gene            4184..4819
                     /locus_tag="A37U_RS49645"
     CDS             4184..4819
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /locus_tag="A37U_RS49645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /protein_id="WP_083933470.1"
                     /transl_table=11
                     /translation="MEGVIPRGRRLPLWWTLRKPVRPLTYHAAHRMFERVNDQAGTAAT
                     LHALRHTAAYRMAEDPSLPLTDVQLVLGHAQLTTTQLYLTPRKEEVIRKLVESREIPLR
                     ERVVGLLVLLYAQPVSRIALLRTDDLILEEATILLRIGDPPTPVPEPLAGLLRELRAQR
                     MAFQGPNADTPWLFPGRRAGQPMRSQPLGELLRHYGVAVQPGRTSALR"
     gene            complement(5356..6087)
                     /locus_tag="A37U_RS48295"
     CDS             complement(5356..6087)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A37U_RS48295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_020497169.1"
                     /transl_table=11
                     /translation="MHIGDSSTHSTGRGLIDGWVTGLATRIRQARPADLPALAGILALA
                     GVPLLSGVRHAVEDGSAATALHAGLDDSPQAFIAAAAPATGDLDRAITEVAPAVSLVLV
                     AEHDRHGIVAGLMAAPPVYLLAHLRTDADASRDHEQLRTLLLRCTKIQAMAVTEPARGH
                     RLGAALLHRCCAVYRRCGHRLVYGQTPPNRDPAEYYRQEGFDVLEPGEPLDLEPACGLH
                     TQLTPAATERICIFLQSPPGL"
     misc_feature    complement(5578..5580)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(5656..5658)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6118..6132)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
     gene            complement(6265..6441)
                     /locus_tag="A37U_RS51480"
     CDS             complement(6265..6441)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A37U_RS51480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_020497170.1"
                     /transl_table=11
                     /translation="MQNTLATRNRDEHDMFDLELKVVPADVQQAEASNADPSFSSCPEC
                     SNPSWKCTPPFRR"
     CDS_motif       complement(6328..6441)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MQNTLATRNRDEHDMFDLELKVVPADVQQAEASNADPS"
                     /locus_tag="A37U_RS51480_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6265..6327)
                     /prepeptide="core"
                     /locus_tag="A37U_RS51480_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="3.10"
                     /molecular_weight="2239.5"
                     /monoisotopic_mass="2238.0"
                     /core_sequence="FSSCPECSNPSWKCTPPFRR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQNTLATRNRDEHDMFDLELKVVPADVQQAEASNADPS"
                     /leader_location="[6327:6441](-)"
                     /alternative_weights="2257.6"
                     /alternative_weights="2275.6"
     gene            6614..9676
                     /locus_tag="A37U_RS43555"
     CDS             6614..9676
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="A37U_RS43555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_169526863.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 8.9e-172,
                     bitscore: 565.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.2e-19,
                     bitscore: 62.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.9e-33, bitscore:
                     108.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTEERYSALGVVYLRTPVLPYGSGTLPYRDREPVDDAWLLRAVV
                     ADPVVREALEVSSESLATVLRRMDSGIELSTAQLRRAAYAACRYLLRMSGRPTPFGVLA
                     GVAVGEFAERGEAEIGTAHGKGVRPDGEWLAAVVAQLQRRPEVLRCLRVCANDLVFERA
                     GRLVLPYVARRGLGAESAQEQSVRATAPVWLVMAAARTPIGCAALLDQLAEAFPGTERE
                     RAVALVAGLVDAGLLQTELSATLTAPDPMRRVLAVLHRTPAPETAQLQRIAALFESYAR
                     ASLGAGRPAWDAATSAARELHPAGTTPIQVDLRADARLRLPQAVAAEAESVAATLLRLS
                     PPEGAAGHLTQWYYAFVDAYGIGASVPVKDALDPERGIGPPAGYQQPPASRFTAPGTED
                     DRRRDRICGQLVQQALLSGSDEIVLDEATIAALAAPGDPAPAPATAELTFQLLAPSVAS
                     VERGDFRLVCASAMANGTGALFGRFGYLVEGGDPAAVQPFAGDARLHGQLSFEPTAARH
                     VNIMRVARAVDHTLAIGTFDDRDRPDVLGIEDIGIAADHDGLFLTSLRDGRLITVTCPQ
                     MLDTDKHAPNAARLVRELGGYGTRTLSPWRWGGVDCLPYLPRVRHGRTVLAPARWRPAP
                     RLVEAARDGTGFDDLQWDAAVAQWQKQLSVPDLVQVRDFDHGVELNLGMPLHRRLLRDE
                     LRRKPDLVFVETAHREESELGWLHGHANEIVVPLRVRRRARAETRSATRPAATRVAVAP
                     GGEWLFAKLYSRPQRHHELLIQHLPRLLDLDGQLRWFFIRYADPDPHVRVRFHGPPELL
                     NQRLLPRLHAWATDLRACGLLRRLTIDTYEPEQDRYGGAAVLAAAERVFCADSAAALAQ
                     LPLLHDPAEPLPPEVLAAVNFVDLLRLLDPGWADWYRGSAVWHYDGMHRHVRQATELAR
                     RLSDTAGALPGTPLPTVHAALADRAPAVRDYAAALHAVGEDGRHRSAVDGMLHMHHNRL
                     IGIDRASEQRANAVASRVIAAHRGRVRAGRE"
     aSDomain        7070..7342
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_A37U_RS43555_Lanthipeptide_LanB_RRE.1
                     "
                     /evalue="7.70E-20"
                     /identifier="RREFam001.1"
                     /label="A37U_RS43555"
                     /locus_tag="A37U_RS43555"
                     /protein_end="243"
                     /protein_start="152"
                     /score="62.4"
                     /tool="antismash"
                     /translation="VCANDLVFERAGRLVLPYVARRGLGAESAQEQSVRATAPVWLVMA
                     AARTPIGCAALLDQLAEAFPGTERERAVALVAGLVDAGLLQTELSA"
     gene            9673..10884
                     /locus_tag="A37U_RS43560"
     CDS             9673..10884
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501486.1"
                     /locus_tag="A37U_RS43560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_083933472.1"
                     /sec_met_domain="LANC_like (E-value: 1.6e-45, bitscore:
                     148.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRSVRLGAVLAATAERLADPATTCPQGPDGARWPTLDSQIGLA
                     LFYAELGHADPGLRPVAHRYLAAANAALSGTGRHTLSAGVPALAFAACAAAHRDGEYAT
                     LLAGLDAAIFGIVGALLDEERKRLASGTVAPDSTRFDLLAGLAGLGRYLLCRCPASAQA
                     EALLREILDYYRLLVRPVTDRRLPGWWVACAPDPSAPPGAGHANLGMAHGIPGPLALLA
                     VAWRNGVRVDRHIETVETIVEFLRTWSDTDERGRYWPAALAIADYTDRPVALPRPRPAW
                     CYGAPGVARAVQLAGLAAGRPDWLALARQAVHDLPEPETETGVCHGTAGLLQLAVRMQA
                     DDPACGLTALADRLAEHTAATLADDGNEDPGLLTGTTGAALALHTHGTGTAPSSGWDGV
                     LLIG"
     gene            11493..11822
                     /locus_tag="A37U_RS0113490"
     CDS             11493..11822
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A37U_RS0113490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_020497173.1"
                     /transl_table=11
                     /translation="MKTFMRRGFVTLVLTVAVAGVVQGQASALDQQTYFWDCGSSRGVT
                     LNVTVYGSQPGMYEVAGGPSGNFPPNQPQSIPMPPGQGQVSVGINGNDPGLIDKTSGVT
                     CNASP"
     gene            complement(12012..13064)
                     /gene="add"
                     /locus_tag="A37U_RS0113495"
     CDS             complement(12012..13064)
                     /EC_number="3.5.4.4"
                     /GO_function="GO:0004000 - adenosine deaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0043101 - purine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /gene="add"
                     /inference="COORDINATES: protein motif:HMM:NF013155.4"
                     /locus_tag="A37U_RS0113495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenosine deaminase"
                     /protein_id="WP_205622924.1"
                     /transl_table=11
                     /translation="MQPNYSTRLSQDANDHPRRDAPLQRRRSLVELPKAHLHVHLTGMM
                     RPHTLAELASRHDVAVPAPVEDYPNFDEFVRAYRAARSVLHTTEELARLVEEMVEDAAE
                     DGAVWIEPSLSLRGYRPITGGDQDTLQVVLDAARQASERFGTGVGVIVAAERGDDPVEA
                     ERAAVVAGEYADRGVVGFGLGGDERHPPSGFARAFAFARESGLLSVPHAGELDGPQSIR
                     ATLEQLSPHRILHGVRAAEDSQLVEQLHEQQVCLDVCPSSNRALGVTPDLAAHPLPTLV
                     RAGVACSINTDATLPFRTTLAREYELCRAQLGLTDHELADVARASLRASAAPAQLASTA
                     IHAIDTWISR"
     misc_feature    complement(12057..12059)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13313..14380)
                     /locus_tag="A37U_RS49650"
     CDS             complement(13313..14380)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1237: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033542.1"
                     /locus_tag="A37U_RS49650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS110 family transposase"
                     /protein_id="WP_083933473.1"
                     /transl_table=11
                     /translation="MDHDVVIGIDPHKTSWYAAVVDGRHRLLSELRVSASRVGYRELRR
                     LARRWPNIRWAIEGSSGLGRPLTQRLADDDIAVIDVPSKLSSRVRELATGHGRKTDQVD
                     ARSVAVAALNGSDRLHQSDEQAETLRLLSEHRDELVRRRTQVVNRLHVLLSHLIDGGAP
                     TWLTADRAAALLGRVRRACGARATRRTLAVDLVAEVRHLNKKISTAEVRVSNALDQLEP
                     SLLQLPGAGPVLTARIIGRAGSLARFPSADHFASYCGTAPIEVSSGDVTRHRLSRAGDR
                     QLNHALHLIALSQIRCHEPARAYYQRKRESGKGHREALRCLKRRLATVIYRHLEADQSD
                     KIPATNWQRGTDANN"
     misc_feature    complement(13520..13522)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14168..14170)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(<14601..15516)
                     /locus_tag="A37U_RS43565"
                     /pseudo=""
     CDS             complement(<14601..15516)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050768036.1"
                     /locus_tag="A37U_RS43565"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS481 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTHANAPLSVEGRRRLVQRCRTRPIAHVAAEMSISRACASKWVNR
                     WRRHGDAGLTDRSSTPHRSPQAAPAWIIEQIEVWRREHKWPAQRITDELADLGHKFNRR
                     TVTRHLNRLGLGRRRFIDPGGDNNRKPGKITARWPGHIMHLDVKKVGRIPDGGGWRVHG
                     RDSDQARATGRAKSAGARRGYIYLHSAVDGFSRLSYTESLNDEKGPTAAAFLACAKAWF
                     AAHGIAHIHRIVTDNGACYRSNDFARIVGQPDAASDDSAVHPTPQRES"
     gene            complement(15513..16769)
                     /locus_tag="A37U_RS43570"
     CDS             complement(15513..16769)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR00710.1"
                     /locus_tag="A37U_RS43570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multidrug effflux MFS transporter"
                     /protein_id="WP_063712788.1"
                     /transl_table=11
                     /translation="MDASRPVSTGGWRARGGRLRLAALLGALSAAPSLAIDMYIPALPN
                     LAADLRASPGQAQLSLTGFLVGLALGQLVAGPVSDMLGRRKPILVGISAFAVGCALCAA
                     AINAPMLVIVRVVAGLVASAGLVIARAVVTDRYQGPDADRFFAALLAIAGLAPSLAPLA
                     GGVLLQVIDWRGVFAVITVLAVAIGVGSFVWLPESLPRERRRTSSEQGTRASTRSLLTN
                     RDFVRFAAAVGLSFASLFAVISGAPFFLEQTYGLTALQTSIVLAINGLGIVLAGQVSTR
                     LVTRTGPWKLVLAGFAVSGSGGIILLTVHVMHAGLWAALIGLFLAMSPVGLVLPNATSL
                     AMATRPARERAGTASAVIGVAQFAFGGIAAPLASAGGATALPIATMALVSVVAGIGLTT
                     SRIAAQHDGRLNDDAGNQA"
     misc_feature    complement(16641..16643)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16823..17284
                     /locus_tag="A37U_RS43575"
     CDS             16823..17284
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024803.4"
                     /locus_tag="A37U_RS43575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_020497178.1"
                     /transl_table=11
                     /translation="MPATYSIGEAARETGLGIHTLRYYESEGVLVDEPQRSPTGRRCYT
                     ENDIEWLIVCRRLRETGMPIESLSRYAALLREGTETEHERLKLLTAHRGKVIDSINQLK
                     SNLELIDLKIDAYRRNLRRVRDGQDLPASTQGRIELQPQPNQEDASTTS"
     gene            complement(17270..17872)
                     /locus_tag="A37U_RS0113525"
     CDS             complement(17270..17872)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A37U_RS0113525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_020497179.1"
                     /transl_table=11
                     /translation="MARAEGFMVVTTVCIVLVSGGLWHLGTVLTGEGTLLAWLAAGLVG
                     AHGALMIAWGSTFVFRVQRAKLRVALRDNRRDLFFGIPIAGLGWAGLLKDYVHGWYFVG
                     SALLFVVAGAAAWYLYVLPIPAIVNRFYDDFFASRITPERRAARRQYMRHQFGIGHDKT
                     TKVGRRARRQARRSERAAMRRRISKYKTSNRCGSGGC"
     tRNA            complement(18454..18523)
                     /anticodon=(pos:complement(18491..18493),aa:Lys,seq:ttt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="A37U_RS51485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Lys"
     gene            complement(18454..18523)
                     /locus_tag="A37U_RS51485"
     misc_feature    18680..18695
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.26"
                     /tool="antismash"
     misc_feature    19116..19129
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.04"
                     /tool="antismash"
     gene            complement(19249..20268)
                     /locus_tag="A37U_RS48300"
     CDS             complement(19249..20268)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A37U_RS48300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157182813.1"
                     /transl_table=11
                     /translation="MTNEIDIRLTGGWPALTEALKLKDCPLKSWLVERFPSTNTKAVFQ
                     AYKNSVGPIRVPASAEPAGGGSGAIGGSFDYLVRFLVDPHPDIELPAAGARRFGGRMPT
                     AVAELAARVGAQPPPLGESTSDTAATRFDGPCVPEPRDTELLARSCWALSLLTELYRGV
                     PPERSPLAVAVNPHTVDAEALLALASAAALDQLAALREQAETILLPALASKRGPWAVGP
                     VFSGSALMNADADLIAAGTLVEIKTLLGSKRQDGTRYATLDAQVLFQMLGYVLLDFDDE
                     FGIHELKLFNARYGHLATWPIQELLDILAGRPIELASLRAEFKQFLRTGGQQAIRARA"
     misc_feature    complement(19525..19527)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19690..19692)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(20221..20223)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    20262..20276
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.36"
                     /tool="antismash"
ORIGIN
        1 cggatcggcg actgcaccac aatgctggcc atggaggagc acgagatcgt cggccgcggg
       61 tcgatggacc ggctgtggat cgtaggcgag acggtgcgcc gcgagcgcgg tgcgcatagc
      121 gataccgtcg cgacgctgtt gacccacttg gagcgacgag ggtatccgta ctcgccgcgc
      181 taccgcggta tcgacgagca gggccgagat gtgctgactc gcttgcctgg cgtgccggtg
      241 ccgaccttgc gcggcgacga ccagcttcgc gaggtcggcg gcgcgatcgc caccttcgcc
      301 gaagcggtgc gcgatttccg tgccccgccg ggagcgctgt ggcgcaatcc ggaggactgg
      361 ccgctgcacg gcgacacggt gatccacaac gatatcgcgc cgtggaacat gctggagcgc
      421 gaccagcgac tgtgcgggct ggtcgacttc gactcggccc ggccgggccg ggcgatcgag
      481 gacgtggcct atgcggcctg gcacatgacc ccgttgcatg acgagctgat gggcgacggt
      541 gctgccccac cggctctggc cgagcgtcct cggcgattgc ggatctttgc cgatgcctgc
      601 ggcctggaca gccaacaacg ctgccggttg ctcgacgagg tggctcgagt ccagatcaac
      661 caagccgccc gggtcgctgc gggcgcgctc ggcccgcggg ctgataccgc gcggcactgg
      721 gacagcgggc ggttcaccgt caacatcgcc cgctccctgc tatggctcga ccaccatcgt
      781 gaccacctcc aacagacact gacctaagcg ctacctcgca gaggatcctg ccgtacgtcc
      841 gcaggttgtc aggacccgtg tctagggtcg gagacatgtc tacctggccc ggcgttcccg
      901 aacgtgtccc acggtgcaaa gtaagacatc gttcatggtg gaagcgccgt ggacggtgag
      961 tgctgagcca gcgacgacgt gcgccgttcg cccgaccata gctcgttgag ctgcgaaaac
     1021 gtgccacctt gcgcctcagg acacgctcag gagcgcgtcg actgttgcgt agcctagtag
     1081 cgtcgatgcc atgttcaaac gggtattggc tgtcgcagta gcaacagcgg gaatggcact
     1141 caccctggcc tcaacggccg gcgccgcgcc tccaccggtc taccgcagct accaggattg
     1201 ccaggtggcc ggtcagaacg ccgtcggcgc cgcgggtggc cccggaaacc tgagctacca
     1261 gtgccaggag atccccggtg tccccgccgg tgtggccggt tgtccaccga acgcgggtcc
     1321 cagtggatgc atcggtgact actacgagct gctgacgtcc tcgccgtagt gggcgaggat
     1381 ttaggagcag cagcgaggat cgacttcaga cgggcccatc tgatccccgc ctacttcggg
     1441 tagccgcagt atccgccgaa aattgggcgg atacgggtgt gagtagcctc gcgacagcag
     1501 gtcggcgttc tgggtcccgg ctggggtcat gttgccgtta gcgagggcca ccgctggatc
     1561 gcccaggccc gccaatcggt ccaaccttgt ggtggggcac ttgggtagtt gccagccagc
     1621 tcgctcgcgt tgggaacatc gaagatctgc tcgtagctat cgatctcggc cgtggtcaac
     1681 accatgcttg cgcagcgcgt ttcgtggtgg cgctgtgcga tccgctgtcg ttgggtggct
     1741 cggtccactg gcagatacac caactcgaac gtgccaccag cttggttggt cagccaccgc
     1801 agcgccgccc gctcgtcgcg cgaccagcat ccgaagtcca acaccacgct cgtgtccaac
     1861 gccagtagcc gcagcgccac ggagatcagc cggccctcga gcacgtcacg cttcccgtcg
     1921 aggtccgggg ctccgaacaa tggcagcatc cactcgtcgg gactgagccg taacgcggca
     1981 cgctcgccgg ccagccgccg cgccatggtc gtcttgcccg aaccaggcaa cccgaccagc
     2041 agaataagta cagccacgac accgatcatc ccggccacgt cctcccgctt gcgttcggca
     2101 cgggtcgcca cagtactggc cgaaccgcaa gccgtgcgga tgaacagctg tccggtgttg
     2161 gtcggctaca ggagctcgaa gaaccggaca gctggcagcg cggtgtagcc gctgttctgg
     2221 tagacccgcc gggcaggagc atgagcaggg tccccgcccg tttcgaccat cgccacccgc
     2281 atgccagagc gctgcagcca gtcggtagcg cggtcagtca gggccgttgc aagcccctgg
     2341 cgctgggcgc tgggcgcgac agcgagcatc gatatttcac cgacgccggt ggcatgctca
     2401 agccgtgcgg cgacgaaacc gataaccgtc tcgtcgggct gctcggccac ccacacctgc
     2461 tggccgggat tggcgagcac gttacgcact gcctgcgcct ggcccgctcg ccaatcaccc
     2521 cgcaaccgac tgaataactc gtcgccgagc agctcctcga tggcggcgaa gaccggttcc
     2581 cacgcgcgca gccccagcgc gacgaccgcg ggttcatcgc ctacctggta atcccgaagg
     2641 gtagccatca ggaatgttgc tggcgaatgg tctggccatc ttgcacgagg gtggcggcga
     2701 actcgccgga catgcccacc ggggtcgaaa cgtccaccag tgccccgttc gggtcggtga
     2761 gcagcagctg ccgttgccca tagaacagat tgcgcggctc agccacgacc gacagttgcc
     2821 ggcgttgcgc ttcggcgtac accgcatcga catcatcaac gacgaaggaa agcaccgtac
     2881 cggctggtgc ttgacggaac cgctcgggga tcagctcgtg gtcgcgccgc cagatgccca
     2941 gatcaccggc cggcgttccg tgcccattct caagatcgag ggctccggat gtcagtggcc
     3001 agtaggaatt ccccactcgc ggccagttcg tctccccacc gtggacaggt cgattccccg
     3061 ctggcggcca ccagcgttac gaaccgtgac tgtcagccgg gcgggttacc ggcgtcgttg
     3121 cgggccccac cacgggaaga tcggcggcag gtcactgaac tcgctggatg gctgccgggg
     3181 ttcgcgggtt tcgccgtcgt cactgtccca gcgtcgaccg tactggtccg ggatcgttcc
     3241 ccagccccag taaggcaccg gtttctgcgg ctggctgccc acggtattga gcggatcaat
     3301 acgctcagaa ccgacggtgc ataggtgcgc ccaattgtcg ccgaggtcga atacataggc
     3361 gaactactcg cccaggttga gcctgctcag cttggtcgct gcgctgtcca gcgcctcgtc
     3421 gggaagttcg ccgtcccagt cgcgcgcgcg gcagaggttc gtgccctcgg ccagggtgaa
     3481 catgtgcaga tgcgcgagat cccaacgggc gaacgcggcg tcgaccgctt cagcaagctg
     3541 cgcgaacgag tgactgcgcg cggcagcgaa cacccgcccc ggtcggggcc acatcacctg
     3601 ccctccgccc gagaccaact caacctggat agataaccac gtgcgagcca cctgccgact
     3661 cctaacacta tgccgaaact ctggcatcct ggacactact gaacgtcacc atagactggg
     3721 gaattcgact ggccgtcctt ggggaatctg aactgtccac tgacatccgg aggtgaggtt
     3781 gacgaaccag tcgctgtcga aagcgactgt gaaccccagc aggctgacgt agaaatcccg
     3841 attatgtggt aatcagactg gaggcccttg actaagagct gaaggacaat acgtcctaaa
     3901 agcacctgtc agacgctcgt ctctatgcgt cagaaaaatg acttaacgac tgcgttacgg
     3961 cattcatggt aatgtcatca gaagaatctg gaagttctac tttgctatta gaaatatcaa
     4021 gttctagagc ttcaaatatc tacacagtaa ttattgaaaa gcagttatac gaccggttca
     4081 cggatcagtt ttcggacata ctactgcatg ctgtggtggt tgtcagcaac tattccccgc
     4141 atcccccgac gcgttcgtgt ggctacggct ctaccaagcg gagatggaag gtgtcatccc
     4201 acgcggccga cgactgccgt tgtggtggac actgcggaaa ccggtccggc cgttgaccta
     4261 ccacgctgcg caccgcatgt tcgagcgtgt caacgaccag gcgggcacgg cggcaaccct
     4321 gcatgctttg cgacacaccg ccgcctaccg catggccgag gacccgtcgc tgccgctgac
     4381 ggacgtccag ctcgtcctcg ggcacgcgca gctcacgaca acacagctct atctgacacc
     4441 ccgcaaggaa gaagtgatcc gtaagctcgt cgagagtcgc gagatccccc tgcgggaacg
     4501 ggtcgtcggc ctgctcgtgt tgctctacgc ccaaccagtc agccggatcg cgctgctcag
     4561 aaccgacgac ctcatcctcg aggaggccac catcctgctg cggatcggtg atccgcccac
     4621 acccgttccc gagcccctgg ccggcctgct gcgcgagctc cgcgcccaac gcatggcgtt
     4681 tcagggcccc aacgcagaca caccctggtt gttccccggc cgtcgcgcag gtcaacccat
     4741 gcggtcacaa ccactcggcg agctcctgcg ccactacggg gtcgctgtcc agcccggccg
     4801 gacctccgcg ctccgctagc tcgtgctaca ggcaccagct ccggttatcg caagcatgct
     4861 cggctaccac gacacgcaca ccacctggct ccgcgccgag accggcggca cctggagccg
     4921 ctacgcaccc ggtgacgatc acaagcagtg acaccgtcct ccgcccgaac gaggcattca
     4981 ggtcggtcga tcacgagcgc ttaccagcat cacaggccag aggcgccgtt gccgttttct
     5041 tgacactccc gtcaaccggc gccactgctc ccgcgctgca agagcgccgc cgcttcgcgc
     5101 tgcgaacgcg gcgcccgcga tcatcagccg gcggcagcgc cggcggtgct cacctcagca
     5161 gacgcacggc cgagaccgac cgcgcaacgc gactgcccac actgcggcgc tccggtcacc
     5221 atcgtcgccc tgctcaccac tccagaagca gcccgcctca ccaggcccat ggcgacatcc
     5281 gatggcgtgg tgccggtccg ccggtaacca ctgaacaccg cgcccaaagc ccgcccactc
     5341 accttcgttt tcgcttcaca gtcccggcgg tgattgcagg aagatgcaga tccgttcggt
     5401 ggctgctggt gtgagctggg tgtggaggcc gcaggcgggt tccaggtcga gtggttcgcc
     5461 cggttcgagt acgtcgaatc cctcttggcg gtaatattcg gcaggatccc ggttcggtgg
     5521 tgtctggccg tagacgagcc ggtgtccaca gcgtcggtat accgcgcagc agcggtgtaa
     5581 tagtgcggcg ccgaggcggt gcccgcgggc gggttcggtg accgccattg cctggatttt
     5641 tgtgcagcgc agcagtaagg tgcgcagttg ttcgtgatct cgtgaggcat cggcgtcggt
     5701 gcgcagatgc gccagtagat atactggtgg tgccgccatt agccctgcga ctatgccgtg
     5761 ccgatcgtgt tctgcgacga gcacaaggct taccgccgga gcgacctcgg tgatggcccg
     5821 gtcaaggtcg ccggtcgcgg gggcggcggc cgcgatgaag gcttgcggac tatcgtcgag
     5881 tccggcgtgc agcgcggttg cggcgctgcc gtcttcgacg gcgtggcgga caccactgag
     5941 cagcgggacc ccggccaatg ccaggatccc ggcgagcgcg gggagatctg cgggccgggc
     6001 ctggcgtatc cgggtcgcga gtccggttac ccagccgtca atgagacccc ggccggtgga
     6061 gtgtgtgctg gagtctccga tatgcattcc gcgtggcttc ccaggcgtgg ctgccggtgg
     6121 ccgagtcctt cccgcgaatt cggtccggcg cggaccggtc atgtgggctt ttcgcccgta
     6181 tcgtggtgtt cagcggctgt ccgctgtgca cgcttcgagc atccccaggg ttcttggtga
     6241 ttcgtctcgg tgctttctgt gtggtcagcg acggaacggc ggggtgcact tccagctcgg
     6301 gttgctgcat tccgggcagc tgctgaacga aggatccgca ttggatgcct cggcctgctg
     6361 cacgtccgcc gggacgacct tcagctcgag gtcgaacatg tcgtgttcgt cccggttccg
     6421 ggtggcgagt gtgttttgca tattcccaac tctcatcgca ggtgtgctgg tcgtgccgat
     6481 cgcgatggca tcgccatcat gacacgagtc acccggattc gctatcaggt cgatttagtc
     6541 tgctcttgac aacggtggtt cggtattgcg caggagcgcc ggggtggtgc ctgagggtcg
     6601 cgaggggatt tgtgtgggta cggaagaacg gtattccgca ttgggggtgg tctacttgcg
     6661 gacaccggta ctgccgtacg gcagcggtac gctgccgtat cgggaccgag agccggttga
     6721 cgacgcgtgg ctgttgcgcg cggtggtcgc tgatccggtg gtccgggagg cgcttgaggt
     6781 ctccagcgag tcgctggcca ccgtgttgcg caggatggac tcgggcatcg agctgagtac
     6841 cgcgcagctg cgccgtgccg cgtacgccgc gtgtcggtat ttgctgcgga tgagcgggcg
     6901 cccgacgccg ttcggggtgc tcgccggagt cgcggtcggg gagttcgccg agcggggcga
     6961 ggcggagatc gggacggcgc acggcaaggg cgttcgcccg gatggcgagt ggctcgccgc
     7021 ggtggtagcc cagctgcagc ggcgccccga ggtgttgcgg tgcctgcgag tgtgcgccaa
     7081 cgacctggtg ttcgagcggg ctgggcgact cgtgctgccc tatgtcgcac gtcgtggtct
     7141 cggtgccgag tcggcgcagg aacagtccgt gcgggccact gcgccggtgt ggttggtgat
     7201 ggcggctgcg cgcaccccga tcggttgtgc cgcgctgctc gaccagctcg ccgaagcatt
     7261 ccctggtacg gagagggaac gagcggtggc cctggtagcg ggactggtcg atgccgggct
     7321 gctgcagacc gagctgtccg cgacgctcac cgcgcccgac ccgatgcgca gggtgcttgc
     7381 ggtactgcac cgaaccccgg caccggaaac cgcgcagctg caacggatcg ccgccctctt
     7441 cgagagctac gccagggcat cgcttggtgc gggccggcca gcatgggatg cggcaacctc
     7501 cgcggcacgg gaactgcacc cggccggcac cacaccgatc caagtcgatc tgcgtgccga
     7561 cgcgcgattg cggctgccgc aggcggtggc ggccgaggcc gagtcggtcg ccgcgacgtt
     7621 gctgcggctg tccccgccgg agggtgcggc ggggcacctc acccagtggt actacgcgtt
     7681 cgtcgacgcc tacgggatcg gcgccagcgt cccggtcaag gacgcgctgg acccggagcg
     7741 gggcatcggc ccgccagccg gctaccagca accgccggcc agccggttca ctgcgcccgg
     7801 caccgaggac gaccggcggc gggaccggat ctgcgggcag ctggtgcaac aggcgctgct
     7861 gtctggttcc gacgagatcg tgctggacga ggccacgatc gccgcgctcg cagcgcctgg
     7921 ggatccagcc cccgcaccgg ccacggcaga gctgaccttc cagcttctcg ctccgtcggt
     7981 agcgtcggtc gagcggggcg atttccggtt ggtctgcgcc tcggcgatgg ccaacgggac
     8041 gggcgcgctg ttcggccggt tcggctatct tgtcgagggc ggcgaccctg ccgcggtgca
     8101 gcccttcgcc ggcgacgcgc ggctgcacgg tcagctcagc ttcgaaccga cggctgcccg
     8161 gcatgtcaac atcatgcggg tggctcgcgc ggtggaccac accctggcga tcgggacctt
     8221 cgacgaccgc gaccgcccgg acgtgctcgg catcgaggac atcgggatcg ccgccgacca
     8281 cgatgggctg ttcctgacct cgctgcgcga cggtcggctg atcaccgtca cctgcccgca
     8341 gatgctcgac accgacaagc acgccccgaa cgctgcccgc ctcgtgcgcg aactcggcgg
     8401 atacggcacg cgcaccctct cgccgtggcg ctggggcggc gtggactgcc tgccctacct
     8461 gccccgggta cgccatggcc gcacggtgct tgcgcccgca cgctggcgac cggcgcccag
     8521 gctcgtcgag gccgcgcggg acgggactgg cttcgatgac ctgcagtggg acgccgcggt
     8581 ggcacagtgg cagaagcagc tcagcgtccc ggatctggtg caggttcggg actttgatca
     8641 cggtgtcgag ctgaacctcg gcatgccgct gcaccggcgg ctgttgcgcg atgaactgcg
     8701 ccgcaaaccc gacctggtct tcgtggagac cgcccaccgg gaggagtccg aactcggctg
     8761 gctgcacggg catgccaacg agatcgtggt gccactgcga gttcgccgcc gtgccagagc
     8821 agaaactcgt tccgcgacca ggcccgcggc cacgcgggta gccgtcgcgc ccggcggcga
     8881 gtggctgttc gcgaagctct acagcaggcc acagcgccac cacgagctgc tcatccagca
     8941 cctgccgcgg ctactggacc tggatgggca gcttcgttgg ttcttcattc gctacgccga
     9001 tcccgatccg catgtgcggg tgcgtttcca cggcccgccg gagctgctca accagcggct
     9061 gctcccgcga ctgcacgcgt gggccacgga tctgcgcgcc tgcgggctgc tgcgcaggct
     9121 caccatcgac acctatgaac cggaacagga tcggtacggc ggcgctgccg tgctggccgc
     9181 cgccgagcgc gttttctgcg ccgacagtgc cgcggcgctg gcccagttgc cgttgctgca
     9241 cgacccggcc gaacccctgc caccggaagt gctcgccgca gtgaacttcg tcgacctgct
     9301 ccggttgctc gatccgggct gggccgactg gtaccgaggc agcgccgtct ggcactacga
     9361 cggcatgcac cggcatgtcc ggcaggccac cgagctggcg cgccggctct ccgataccgc
     9421 tggcgcgttg cccggcacac ccctgcctac cgtccacgcc gccctcgcgg accgtgctcc
     9481 cgccgtacgc gactacgccg cggccctaca cgcggtgggg gaagacggaa ggcaccgcag
     9541 cgcggtcgat ggcatgctgc acatgcacca caaccggctg atcgggatcg accgtgcgag
     9601 tgaacagcgg gccaacgccg tggccagcag ggtgatcgcg gcccaccgcg gccgcgtcag
     9661 agcaggccgc gaatgagtac ccggtccgtg cggctcggcg cggtgctcgc cgccaccgcc
     9721 gagcggctag ccgatccggc caccacctgc ccgcagggtc cggatggtgc ccggtggccg
     9781 acgctggaca gtcagattgg gcttgcgttg ttctacgccg aactcgggca cgccgacccg
     9841 ggcctgcgtc cggtcgccca ccgctacctc gccgccgcga acgccgcatt gtccggcacc
     9901 ggcaggcaca ccctgtccgc gggcgtcccg gcactggcct tcgccgcgtg cgccgccgcg
     9961 caccgcgacg gtgagtacgc cacgctgctc gccgggctgg acgccgcgat cttcggtatc
    10021 gtcggtgccc tgctcgacga agagcgcaag cggctggcca gcgggacggt ggcgccggac
    10081 agcacccgct tcgacctgct cgccgggctg gccgggctag gcaggtacct gctgtgcagg
    10141 tgtccggcga gcgcgcaggc agaagcgctg ctgcgggaga tcctcgatta ctaccggttg
    10201 ctggtgcggc cggtaaccga ccgccgcctg cccggctggt gggtggcctg cgcgcccgac
    10261 ccaagcgcgc caccaggggc cggacacgcc aacctcggca tggcacacgg catccccggt
    10321 ccgctggcgc tgctggccgt agcgtggcgg aacggggtgc gtgtggacag acacatcgag
    10381 accgtcgaaa ccatcgtcga gttcctccgc acctggtcgg acaccgacga acgcggccgg
    10441 tactggcccg ccgcgttggc gatcgccgac tacaccgacc gccccgttgc gctgccgcgt
    10501 ccccggcccg cctggtgcta cggcgccccc ggcgtggccc gcgccgtaca gctcgccggg
    10561 ctggccgcgg gccggccgga ctggctcgcg ctggccagac aggcagtgca tgatctgccg
    10621 gaaccggaaa ccgagaccgg agtctgccat ggcacggcag gcttgctgca gctggccgtg
    10681 cggatgcaag ccgacgaccc cgcctgcgga ctcaccgccc tggcggaccg gctcgccgag
    10741 cacaccgccg ccacactcgc cgatgacggg aacgaggatc ccggactgtt gaccggcacc
    10801 acaggagcgg cactcgccct acacacccac ggcaccggca ctgcgccgag cagcggatgg
    10861 gacggtgtgc tgctgatcgg atgaggtcat gcgatagacc cggccgattc ggcaagcgcg
    10921 ccgtcagcac ggctgacact cccgctgttg gtcacgcctg cttcccggcc acgatcgtgt
    10981 accgaatagg tggccgtgcc tgcccattgc tgcgtcgctg acctgccatg atgtgagcgt
    11041 tggcggctct tgccgacttc cttaccgcgg ctactgttcc acaccatgcc tgttgcgtca
    11101 tgtgcatttc ggctgccacg atgcagcagt gcgatgttga catttgggga ggttgaggac
    11161 atgaggcacc tgacaggtgg cgcgttcgcg gtctttgcct cgtgcgttct ggccgtgcca
    11221 ctggccggga cagcacacgc agagatcatc ggaccgggga acccctattt ctgggactgc
    11281 ggttcctcac gcagtggtgg catcctcgta gaagcctttg gccaaaacat tcgggtcata
    11341 gtcaaccccg acaacgggcc gtcgcgagaa gagactcgaa gcgggagtat ctccgagcgg
    11401 tttgatggcg gctcgagcgg caacgccgcg atattcacga gtaatgacgg cggatttggg
    11461 cccggcaccc gggtttactg tgacggtgcg ccgtgaagac cttcatgcgc cggggcttcg
    11521 tcacgttggt gctgaccgta gccgtggctg gagtcgtgca ggggcaagcg agcgcgcttg
    11581 accagcagac ctacttctgg gactgcggca gctcccgtgg cgtgacgctc aatgtcaccg
    11641 tctatgggag ccagccgggg atgtacgaag tcgccggcgg cccatccggg aattttccgc
    11701 ccaaccaacc gcagagcatt ccaatgcccc ccggccaagg ccaggtcagt gtcggtatca
    11761 acggcaatga ccccggcttg atcgacaaga cttccggagt gacgtgtaac gcgtcgccat
    11821 gacgcgcgag ggggcacatg ctgccagcag tttcaccgcg tggcgacgcg ctgaggcagg
    11881 cagctcagcg cgggctggtg gtgctggtca gacatcaccg ccccggcgaa cctatgcggt
    11941 cacagcacta gcgaatcctc aaccggccac caccgtacgg aatcggttcg gcaactggca
    12001 ctggattggt gtcagcggct gatccatgtg tcgatggcgt gtatggcggt ggacgctaat
    12061 tgcgcgggtg cggcgctggc gcggagggat gcgcgtgcga cgtcagcgag ttcgtggtcg
    12121 gtcaagccga gctgggcgcg gcagagttcg tactcgcggg ccagagtggt gcgaaagggc
    12181 agggttgcgt cggtgttgat gctgcaggcc actccggctc gcaccagggt aggcaggggg
    12241 tgggctgcca ggtcaggcgt gacacccagc gcgcggttgg agctcgggca cacgtccaga
    12301 cacacctgct gttcgtggag ctgctccacg agttgggaat cttcggcggc gcggacgccg
    12361 tgcaagatcc ggtgcgggct cagctgttcg agggtggccc ggatcgactg ggggccgtcg
    12421 agctcgccgg catgcggcac ggatagcagc ccggattcgc gggcaaaggc gaaggcgcgg
    12481 gcgaacccac tgggcgggtg gcgctcgtcg ccgcccaggc cgaacccgac cacgccgcgg
    12541 tcggcgtact cgccggccac gacggcggcc cgttcggcct cgaccgggtc gtcgccccgc
    12601 tcggcggcaa cgatcacccc gacaccggtg ccgaatcgct cgctggcctg ccgcgccgca
    12661 tcgagcacca cctgcagcgt gtcctgatca cccccggtga tcggtcggta gccacgtagc
    12721 gacagagagg gttcgatcca cactgccccg tcctcggcag catcttcgac catttcttcg
    12781 accaaccggg ccagctcctc ggtggtgtgt agcacagatc gggccgcgcg gtaagcacgg
    12841 acgaactcat cgaagttggg gtagtcctcc accggcgccg gtacggccac gtcgtgacgc
    12901 gaggccagct cggccagcgt gtgtggccgc atcatgccgg tcaggtgcac atgcaggtgc
    12961 gccttgggca gctcgaccag cgatcgccgt cgttgcaacg gcgcgtcgcg ccgcgggtga
    13021 tcgttcgcgt cttgggacaa tcgcgtcgag taattcggtt gcaaggaagc actcccacgt
    13081 agcaacaaga ccggacacga agtccgaaca ctggacacag gtcaccttgc cgactctggt
    13141 cagatacatg gagcggcatc gcggcgcacg ggatcggcgc cgaaaagcgg aaacacccgc
    13201 gacttgcaac tcaccagcgg caagttaacc gccacagacc agtacgagca accgttcgcc
    13261 gagctgtgtg ccaacgttac aagtgatcgg tcaacattac atctcgatct tgctagttgt
    13321 tagcgtcagt ccctctctgc caattggttg ctggaatttt gtccgattga tcagcttcga
    13381 ggtggcggta gatcacggtg gcaagtcgtc gtttgaggca tcgtagggct tctcggtgtc
    13441 ctttgccgga ttctcgtttc cgctggtaat aggcgcgggc tggttcgtgg cagcgaattt
    13501 ggctcaacgc gatgaggtgt aacgcgtggt tgagttgacg gtcaccggcg cgggagaggc
    13561 gatgtcgggt tacgtcgcca gaggacactt cgatgggcgc ggtgccgcag taggaggcga
    13621 agtggtccgc gctgggaaaa cgtgcgaggg atccggcccg gccgatgatg cgggcggtca
    13681 ggaccggccc agctccgggg agttgcagca gcgatggttc aagttgatca agagcattcg
    13741 acacgcggac ttcggcggtg ctgatctttt tgttcaggtg gcggacttcg gcgaccaggt
    13801 cgaccgcgag cgtgcgccgg gtggctcggg ccccgcaggc gcgccgaacc cgaccaagca
    13861 gcgcagcggc gcggtcagcg gtgagccagg tcggcgcccc accatcgatg agatgtgaga
    13921 gcagcacatg gagccgattg acgacctggg tgcgacgtcg gaccaattcg tcacgatgtt
    13981 cgctgagcaa ccgcaaggtc tcggcctgct cgtcggactg atggagacgg tcgctgccgt
    14041 tgagggcggc aacagcgact gagcgggcat cgacttggtc ggtcttgcgg ccatgtccgg
    14101 tggccagttc gcggacccga ctgcttagct tcgatggcac gtcgataaca gcgatgtcgt
    14161 cgtcggctaa gcgttgcgtc agcgggcggc cgaggccgct actgccctcg atagcccaac
    14221 ggatatttgg ccagcggcgg gcaaggcgcc gtagttctcg gtaaccgaca cgactcgcgg
    14281 acacacggag ttcgctaagc agtcggtgac ggccgtcaac gaccgccgcg taccaactgg
    14341 tcttgtgcgg atcgattccg atgacgacat cgtggtccat atgcacttcc ctctcgctac
    14401 atgttcagtg ggagcgcgga gggcagactg acgtccagca cagcagacct ctcttgggcc
    14461 actccgcgcg gcgggaccac ggcggacaca agctaccagt gagccagcca cgcggcggca
    14521 agttgtagtc gagcgatccg accgtggtcc cttggcccca agcctgcagc gccaggaccc
    14581 aacgtcaaat gaccacgtca gttgtagtgg atgttccata cggcgatcgc ggcggtgcgg
    14641 gcggtttcgc tggagaactc gcgggcgtag agcagttcct cggccagaat gcgttggtag
    14701 cgctcaactt tcccgttgtg gcgtggggtg tacggccgag tcgtctgatg ccgcgtctgg
    14761 ttgcccgact atccgtgcga agtcgttaga gcggtaacac gcgccgttgt cggtgacgat
    14821 gcggtggatg tgggcgatgc cgtgggcggc gaaccaggcc ttcgcgcagg ccaggaacgc
    14881 ggcggccgtt ggtcctttct cgtcgttgag ggattcggtg taggagagcc gggagaaacc
    14941 atcaacagcg gaatgcagat agatgtagcc gcgtcttgct ccggctgatt tggcgcggcc
    15001 tgtggccctg gcctggtcgc tgtcgcggcc atggactcgc catccgcctc cgtccgggat
    15061 ccggccgacc ttcttcacgt ctaggtgcat aatgtgccca ggccagcggg cggtgatttt
    15121 gccgggcttg cggttgttgt ccccgcctgg gtcgatgaac cgacgccgtc cgagaccgag
    15181 tcgattcagg tgccgagtca cggtgcggcg gttgaacttg tggcccaggt cggcgagttc
    15241 gtccgtgatg cgttgcgcgg gccacttgtg ctcgcgtcgc cagacctcga tctgctcaat
    15301 gatccatgct ggtgccgcct gcgggctccg gtggggtgtc gaggaacgat cagtgagccc
    15361 cgcgtcgccg tgtcgtcgcc accgattgac ccacttcgac gcgcaagcac gggagatgct
    15421 catctccgcg gcgacgtgag cgatcggccg agtccggcaa cgttgcacaa gccggcgacg
    15481 cccttcaact gacagtggcg cgttggcgtg cgtcatgcct ggttccccgc gtcgtcgttg
    15541 agcctaccgt cgtgttgcgc agcgattcgg ctcgttgtta gtccgatacc agcgaccacg
    15601 gagacgaggg ccattgtggc gatcggaagt gccgtggcgc cgccggcact ggcaagtggt
    15661 gctgcgatcc cgccgaatgc gaattgggcg acgccgatca cagccgaggc tgtgccggct
    15721 cgctctcgcg ctggtcgggt cgccatagcg aggctcgtcg cgttcggcag caccagcccg
    15781 accggagaca tcgccaggaa cagcccgatc aacgccgccc acagaccggc atgcatcacg
    15841 tggacggtga ggagaatgat cccgcccgaa cccgagacgg cgaacccggc caacaccagc
    15901 ttccacggcc cggttcgggt gaccaatcga gtgctgactt gccccgcgag aacgatgccg
    15961 aggccgttga tcgccagcac gatactggtt tgtagtgccg tcagaccata tgtctgttct
    16021 aggaagaagg gagctccaga gatcactgca aacaaggacg caaaacttag tcccactgcg
    16081 gcggcgaatc tcacgaagtc ccggttggtg agaagggacc gtgtcgaagc ccgcgttcct
    16141 tgctccgagc tggtcctgcg ccgttcgcgg ggcagggatt ccgggagcca cacgaacgag
    16201 ccgactccga tggctacggc aaggacagtg atcacggcga aaacaccgcg ccaatcgatc
    16261 acttgcagca acacgccacc ggcgagaggc gccaatgatg gtgccaagcc agcgatcgcc
    16321 agcagcgcgg cgaagaagcg gtcggcgtcc ggtccttgat atcgatcggt aacgacggca
    16381 cgcgcgatga ccaaccccgc agacgccacg agaccggcca caacgcgcac gatgacgagc
    16441 atgggcgcat taatagcggc ggcgcacagt gcacatccaa cggcgaaggc ggagataccg
    16501 accagaatcg gtttgcgccg tcccaacatg tcgctgactg gtcctgcgac cagttgaccc
    16561 agcgcgaggc ccacgaggaa tccggtcagg cttagctgtg cctggcccgg cgaggcgcgc
    16621 agatcggccg caaggttcgg taaagccgga atatacatgt cgatggccag cgacggagcc
    16681 gcactcagcg cgcccaacag cgctgcaagc cgcaggcggc caccacgagc gcgccatcca
    16741 ccggtggaga ctggtcgcga agcatccatg cacccggacg ctagaatcta gagtcaactc
    16801 tagatcaagg agatggggct gaatgcctgc cacgtattcc atcggcgaag ccgcccgcga
    16861 gaccggactg ggcatccaca ccctgcgcta ctacgaatca gagggtgtgc tcgtcgacga
    16921 gcctcaacga agcccgactg ggcgacgctg ctacaccgaa aacgacatcg aatggctcat
    16981 cgtctgtcgc agactgcgtg agacagggat gccgatagag agcctcagcc gctacgcggc
    17041 cctactacgt gagggcaccg agaccgaaca cgaacgtctc aagctgctca ccgcgcaccg
    17101 tggcaaggtc atcgactcga tcaaccagct caagagcaac ttggaactca tcgacctcaa
    17161 gatcgacgcc tatcgccgga acctgcgacg agtccgcgac gggcaagacc taccagcttc
    17221 cactcaaggc cgcatcgaac tccagccgca accgaaccaa gaggacgcgt caacaacctc
    17281 ctgacccgca acgattagac gtcttgtatt tcgagattcg acgccgcata gcggcacgtt
    17341 cggaacgcct cgcttgacga cgagcccgcc gccctacctt ggtagtcttg tcatgaccga
    17401 tcccgaactg gtgccgcatg tactggcgac gcgcagcacg gcgctccggg gtgatacggc
    17461 tggcgaagaa gtcgtcgtaa aaccggttca cgatagccgg aatcggcaac acgtacagat
    17521 accaggcagc agcacccgcc acgacaaaca gcagcgcact gcccacgaag taccagccgt
    17581 ggacgtagtc cttgagcaga cctgcccacc ccaacccggc aataggtatc ccgaagaaca
    17641 aatcacgacg attgtcccgg agcgctacgc ggagcttcgc gcgctgtacc cggaacacga
    17701 aggtgctccc ccaggcaatc atcaacgccc catgcgcacc gaccagtccc gccgccagcc
    17761 acgcaagcag agtcccctcg cccgtcaaga cggtacccag atgccacagc cctccagata
    17821 ccaacacgat gcagaccgtg gtcacaacca tgaagccctc ggcccgcgcc atatcacgac
    17881 gaacctctta ctgataggca cagcacgcca tctcccaacg accgatgttg tcctgcggcg
    17941 ccgattgtgc atcccagccc tgacagttcc cggaattaca gacgaccccg acccggcaac
    18001 acccgaccat gcgacggcat cgttccaagg caaccagcac cgaaactacc gtgaactcgt
    18061 tggaaacctg tccgcagcaa ctccctgcca ggaaagcgca agcccatcaa ccagcgataa
    18121 cgcacccctg ccccatcaat cgacgcaccg acagtcccgc acacaccgcc gacagaccca
    18181 cgctccgaaa gtgcaagccc gggccacgac gacacaacga ggcataccgt ccgtaactag
    18241 ccccgacaag cattcaccac cacgaagtca ctgtcgataa ccagaaaggc aggccagtca
    18301 acgccgttca cctacgccga ccactgtcca ctccggacca gcgccagcac accagtgaaa
    18361 attgagcacc cacggagcac cacagcgcca ttcacaccag caaagatgat catcaaacca
    18421 gagaaaaacc aggtcaaacc cggtgtttgc gagtgggccg cctggggctc gaacccagaa
    18481 cctacggatt aaaagtccgc agctccacct ttcaggtagc gccgccgagt gccgacccat
    18541 gccggtttgt gcagctcata cggtagatcc cgttcccgtg gcgccaacct gtgccggcag
    18601 ttcttcgaca cacgagccca gatggagccc ggtgcccccg cactttagtc ctaagtggac
    18661 agataccgtt gtgacagcga cgcctgtagc gaatctgtag cacctatccg catggaaggc
    18721 tggctcatcg gtaggacgtc agtatctccg tcggacaggt ctccacgaac accaccttcc
    18781 aggatcgata tggccgtagc cgcgaaggca gcgctgttgc cggcagtatc aacaccgcac
    18841 tcgcttgggg ccagcacgac ctgtccaaca acaacgcatc caggtcatgg aaagtggtcg
    18901 tcgagggatt ctacaacccg actgacccct gtcatccgct gcgctggttt gaccgcgacg
    18961 ccctacgcga gcagtgcaag tcgaagcttg ccttggtccg gttaccgaaa gaggaacagg
    19021 acgcgagtac gacggaagcg ctcgatcaca cgtcagagtt gatatctctg cgaaaggcca
    19081 gtgggtcgcc cgagtaacag ctcatccacg acaccgaaac ggctgttggt ttactcaatg
    19141 tccatgctgt gctgctcgtt cacgaccact gtggcggcgt tgcctggggc caggccacac
    19201 cgctgtgagt ggcggtctgg cccgcacgcg gtctggctag gtcgttggct acgcgcgcgc
    19261 ccggattgct tgctggcctc cggtccggag gaactgcttg aattcagcgc gcaatgaggc
    19321 cagctctatg ggacggccag cgagtatgtc cagcagctct tggattggcc aggtggcgag
    19381 gtgcccatag cgcgcgttga acagcttcag ctcgtggatg ccgaattcgt cgtcgaaatc
    19441 caggagcacg tagccgagca tttggaatag cacttgggcg tccagggtcg cgtaacgggt
    19501 gccgtcctga cgtttgctgc cgagtaaggt cttgatctct accaaggttc cggcggcgat
    19561 gagatcagcg tcggcgttca tcagagcgga accggaaaat accggtccga cagcccaggg
    19621 gccgcgtttg gaagcgagcg caggcagcaa tatcgtctcg gcttgctctc gtagggcggc
    19681 gagttggtct aacgcggcgg ccgaggcaag agcgagcagc gcctcggcgt caacggtgtg
    19741 gggattcacc gcgacggcca gtggcgaacg ctctggtggc acgccccgat acagttcggt
    19801 gagcagggat agcgcccagc agctacgcgc cagcagttcg gtatcgcggg gctcgggaac
    19861 acagggtccg tcaaatcggg tcgcggcggt gtcactcgtc gactcgccga gaggcggtgg
    19921 ctgagcacca acgcgtgccg cgagttcagc cacggctgtt ggcattcgac cgccgaaccg
    19981 gcgtgccccg gccgcgggca gctcaatgtc cgggtgcggg tccacgagga agcgcaccag
    20041 gtaatcgaag ctgccaccga ttgctccgct gccaccaccg gcaggttccg cgctggcagg
    20101 aacccggatc gggcctacgg agttcttgta cgcctggaac acggccttcg tgttcgtgga
    20161 cgggaagcgc tcaaccaacc atgacttgag cgggcaatcc ttcagtttca gggcctcggt
    20221 taatgcgggc cacccgccag tcaggcggat gtcgatctca ttggtcatcg gtttcaccgc
    20281 ccgtattctg cgtcgtagcg ttgtttgagt tcggcggcgc gtcgttcgtc gcaggtgtgt
    20341 ccgggcattt cgggatcaca gcggagtttg agtaggcggg aacggatcgc gccgggcgag
    20401 cggccgtggt gttccgcgag ttcgacacgt aacgcttctg cgtcggttgt ggtgctggcg
    20461 ctgagccact gatcgtggag ggctgcttcg tcttcacggg tccagctcgc gtgggacagg
    20521 cggggtccgc cggggcgagg tgggagacga cgacgcgttg gctgtgctgc cacggttcgt
    20581 tcgggcagca acggccaggt tttcgctgcc gcgcgagtgt cggtagcatg gtcacgcagc
    20641 cgtgcgacct cggtcgcgtt ggctccctcg ttgacgagct tgcgggcacg ccagtcgagc
    20701 ttgtccgcga agtctgtctg gtgcgcgcgg aaccagcggg actgctgtcc atggagttcg
    20761 cgcggtgcga ccaggccgat ctgggtgggg cgactcgtcg ctagccgcca ggctagccga
    20821 gctgcggcga gcgcgtcttc ggtgccgtcg tgggcttggt cgaggcgtac tccgtagtgg
    20881 acac
//
