LOCUS       NZ_KB905385            26215 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Sciscionella marina DSM 45152 A37UDRAFT_scaffold_13.14, whole genome
            shotgun sequence.
ACCESSION   NZ_KB905385
VERSION     NZ_KB905385.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Sciscionella marina DSM 45152
  ORGANISM  Sciscionella marina DSM 45152
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Sciscionella.
REFERENCE   1  (bases 1 to 133201)
  AUTHORS   Kyrpides,N., Huntemann,M., Han,J., Chen,A., Mavromatis,K.,
            Markowitz,V., Palaniappan,K., Ivanova,N., Schaumberg,A., Pati,A.,
            Liolios,K., Nordberg,H.P., Cantor,M.N., Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Sciscionella marina DSM 45152
            collection_date                   :: SEP 2006
            lat_lon                           :: Missing
            depth                             :: 516 m
            alt_elev                          :: Missing
            country                           :: China
            num_replicons                     :: Missing
            ref_biomaterial                   :: DSM 45152
            biotic_relationship               :: Free living
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: 19196758
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Sand; Sediment; Marine; Aquatic
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            GOLD Stamp ID                     :: Gi11892
            Current Finishing Status          :: Level 2: High-Quality Draft
            Type Strain                       :: Yes
            Funding Program                   :: DOE-CSP 2012
            Isolation Site :: Marine sand sediment at a depth of about 500 m,
            the northern South China Sea
            Cell Shape                        :: Rod-shaped
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28 C
            pH                                :: 7
            Gram Staining                     :: Gram+
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000379465.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 01:37:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,209
            CDSs (total)                      :: 8,146
            Genes (coding)                    :: 7,961
            CDSs (with protein)               :: 7,961
            Genes (RNA)                       :: 63
            rRNAs                             :: 4, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 185
            CDSs (without protein)            :: 185
            Pseudo Genes (ambiguous residues) :: 1 of 185
            Pseudo Genes (frameshifted)       :: 52 of 185
            Pseudo Genes (incomplete)         :: 155 of 185
            Pseudo Genes (internal stop)      :: 15 of 185
            Pseudo Genes (multiple problems)  :: 34 of 185
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:59:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 52661
            Orig. end                         :: 78876
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB905385.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405877
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Nikos  Kyrpides (nckyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-PGF and JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26215
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26215
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26215
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16215](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16215)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            484..1644
                     /locus_tag="A37U_RS43450"
     CDS             484..1644
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="A37U_RS43450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine kinase"
                     /protein_id="WP_020497087.1"
                     /transl_table=11
                     /translation="MTELQQTDPPRLSVFSWVAIHALGTVVVIANLAATQETEPWMWAV
                     YGCTVALWPVYLVLDFHDSGLTWVPLALGGLVNAVVDGFAVDVTAMLFVAVFIARMTSL
                     PTLRLSVALAAPFLAGALVAGSEAVFGELQFDHVLTVVMLGIVGFGLRQYRAQAMATRE
                     LLEQTRRTQAEQARAAALDERTRIARELHDVLAHSLGALGVQLEVAEAMLTEGGDPQAA
                     TARVSRARRLAAEGLAEARSAVAALRGEVPPLAEALTEITAAHGRDHQTETGFTCTGTP
                     RPLDAAVTVALLRVAREALTNAAKHAPGAPVAVRLAFDTDTVGLTVHDSGAGGAVDAAG
                     GGHGLTGMAERLALAGGSLEAGPSDGAEGRGWTVRVSVPDQQGEQA"
     gene            1641..2285
                     /locus_tag="A37U_RS0113035"
     CDS             1641..2285
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466818.1"
                     /locus_tag="A37U_RS0113035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_020497088.1"
                     /transl_table=11
                     /translation="MIGVLVVDDQHLMREGLVALLGMCADIEVVGEAADGNAAVEFVAE
                     HGPDVVLMDLRMPVLGGAEATRQILARRSGTAVLVLTTYADDESISEALGAGARGYLTK
                     DAGRDEIAAAVRSAAAGHATFDRTVSDRLLAAFSGAASQESSGKPVGLTGREAEVLGLI
                     ADGLSNADIAAHLVIGETTVKTHINNLFAKIGVRTRAEAVRYAFRIGITGS"
     gene            complement(2308..2946)
                     /locus_tag="A37U_RS0113040"
     CDS             complement(2308..2946)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020502161.1"
                     /locus_tag="A37U_RS0113040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_020497089.1"
                     /transl_table=11
                     /translation="MTHPANGAGSPLHLNRPRGRDAWRFARQFFRSPMTTASLVPSSSY
                     LAERMVAPIPRTGDPAVVELGAGTGAFTAAAQRVLGGRGTHVAIECNREWARLLASRYP
                     GVDVVCADAHDLLDVLAARGMRADVVISGLPWAAYWPKDKQPLVELVADSLVERGSFTQ
                     FSYAWSRWAPPARRQHRELRENFEETVVSRTVMRNFPPAYVYFARRPRA"
     gene            complement(3070..3699)
                     /locus_tag="A37U_RS0113045"
     CDS             complement(3070..3699)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF028506.4"
                     /locus_tag="A37U_RS0113045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5134 domain-containing protein"
                     /protein_id="WP_083933454.1"
                     /transl_table=11
                     /translation="MTRSTTVGKKTPGSHRITRIGLGSLGAVAVLVVSSGHVLGTWAAL
                     LAALLFAAVLVVHLSHMRGVDRPLAVWHAGHVLMAAGMVLMNLPWLTIPSLLAQGVFLA
                     CALAGLVLAVSGRMRGHGLITLAPMGVIDLLGMAFMYVVPTPGFAWLTVVFAAWFLAQA
                     GWWARGRGPTAAQHGAAVRVSLAVMGLGMASMLVAMQFLMSPMPGM"
     gene            3772..6150
                     /locus_tag="A37U_RS43455"
     CDS             3772..6150
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014998.4"
                     /locus_tag="A37U_RS43455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="WS/DGAT domain-containing protein"
                     /protein_id="WP_157182804.1"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 1.7e-08,
                     bitscore: 27.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEAPSVKRVLIVSANMGEGHNATGRALEERVHVLWPDAQVRWVD
                     TLDAMGKAVGPAFRWTYVTNVESTPWLYEFFYDSLWHRPWFAHAAKRFVAEWAGRSLRG
                     VLREFRPDLVLPTYPLGTAGLNWLRRRGELSAPVGAWISDFAPHPFWVYDRIDRNVVMH
                     DVATGPARVCVPKAPVSVSRPPVTGRFVPGDRLAARKRLGLPVDGFVAVVSCGSLGFGS
                     VAAAVHELLSADESVTVLAVCGRNDALRAKVNAVSPGDPRLIAYGWTDEVPELLAACDV
                     LVTNAGGATSLEALACERAVLMYQPIAAHGKANARLMADAGLAILCPDRGSLTRTVREL
                     LAEPTRLAAIERRAREHVRDHPSLDEALVDLAGSVPAPHRVRAQDSIFLYADGKNHPQQ
                     LGAVLVLHPKEDGTLPGRAEAEVLFGALPGGRNRMRRRWLRHPRLVDDRIGDSDIRLSL
                     VDISEQVAEQGEEAALDAALGEFFSARLDPYQYAGRARLVSGLEGGRAAFLVSSHHSFA
                     DGMAVTGSLVSASRGNPWPQELAPFDEPETVTPRQLVRGLYTLARGGAVKPNSLNRAVT
                     TRERRYRRAWLDQPGLNEIATELGVTVPDVVLGLLAEALRAEVPDTQNGARLTVPQSTR
                     SVRTFRSAGNHTGAIRLDLPVAEMELPERIKRTAEALRDEEESGAPAAARLVVRVMGGL
                     PAPLHRMLAANFNSGNWFNMIASILPGARGVLKVRGSLIGSVYPILPLAKGTAFAAGFM
                     LWAKEVTVCIATDPDGAETAERLCARIEAEYAALRMRTA"
     gene            6307..7035
                     /locus_tag="A37U_RS0113055"
     CDS             6307..7035
                     /NRPS_PKS="Domain: PKS_KR (9-162). E-value: 7.2e-07. Score:
                     21.2. Matches aSDomain:
                     nrpspksdomains_A37U_RS0113055_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005452329.1"
                     /locus_tag="A37U_RS0113055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_338055005.1"
                     /transl_table=11
                     /translation="MSMNWAGARVLITGASSGIGAELARLLARRGAHILAAGRTGSALH
                     GHENFAGDLAEPGACVELAAAVGDVDVFIGNAGFGYAGDFAAMPTDRIGELITVNLTAN
                     MLLTRALLPGMLDRGHGALAYITSIAGAMAVAEEAAYSGAKAGMATFAESVRLAARPKG
                     VRVTTVVPGVVDTAFFERRGAAYDRSRPRPVAPQRVAEATIAAIERGRAEVFVPSWLRF
                     PARLGGAAPGLVRALRSRFE"
     aSDomain        6334..6792
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A37U_RS0113055_PKS_KR.1"
                     /evalue="7.20E-07"
                     /label="A37U_RS0113055_PKS_KR.1"
                     /locus_tag="A37U_RS0113055"
                     /protein_end="162"
                     /protein_start="9"
                     /score="21.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VLITGASSGIGAELARLLARRGAHILAAGRTGSALHGHENFAGDL
                     AEPGACVELAAAVGDVDVFIGNAGFGYAGDFAAMPTDRIGELITVNLTANMLLTRALLP
                     GMLDRGHGALAYITSIAGAMAVAEEAAYSGAKAGMATFAESVRLAARPK"
     CDS_motif       6337..6423
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A37U_RS0113055_0001"
                     /evalue="1.60E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="A37U_RS0113055"
                     /protein_end="39"
                     /protein_start="10"
                     /score="20.8"
                     /tool="antismash"
                     /translation="LITGASSGIGAELARLLARRGAHILAAGR"
     gene            complement(7042..7998)
                     /locus_tag="A37U_RS0113060"
     CDS             complement(7042..7998)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012907.4"
                     /locus_tag="A37U_RS0113060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="chitinase"
                     /protein_id="WP_020497093.1"
                     /transl_table=11
                     /translation="MSRKSFLATAVAAVTGCALAVPFTADAQTTASATAAPYVDMSNSQ
                     VDMLHQAITGAGLKSFSAAFVTGSGCDQIWGDTLPIGKDPKVDGEIEKARSEGASPIIS
                     TGGAAGLPLAWTCTDQQAIQKGYQQIIDTYKVNQLDFDIEGAAQNDTAAAARNMKAVKA
                     LKASNPDLEISVTLPVLPDGLTQDGLKPVQAAKDAGVRIDIVNIMAMDYNQGSQDMGKA
                     ATSAAQATLKQIQGIDSGYSNANIGITPMIGTNDDNSTLTMDNAKAVAEWAKSNQVGRL
                     SFWSLNRDKACDSAARASSTCSGVAQSPLDFTKAFTG"
     gene            8161..8349
                     /locus_tag="A37U_RS0113065"
     CDS             8161..8349
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657571.1"
                     /locus_tag="A37U_RS0113065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_020497094.1"
                     /transl_table=11
                     /translation="MIDRFEAGKDTVQELTESASAHIGNIATIVTGAVRDVARETGDWL
                     TELITMPEAAARSTRDE"
     gene            complement(8402..9412)
                     /gene="hpnH"
                     /locus_tag="A37U_RS0113070"
     CDS             complement(8402..9412)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983007.1"
                     /locus_tag="A37U_RS0113070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_026197179.1"
                     /sec_met_domain="PF04055 (E-value: 7.4e-17, bitscore: 55.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.4e-11, bitscore: 36.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVPVRQALRVGAYIFKNKIRGVKKFPLVVELETLFACNLSCAGC
                     GKIQHPADVLKRRMPVEQAVGAIEESGAPMVAISGGEPLMHPQIDVIVNELVKRKKFVT
                     LCTNAMLVRKRIDKFDFKPSPYFQWAIHIDGLRDAHDASVCKEGVFDEAMEAIKELQSR
                     GFRVTSNSTFFSTDTPQSIIDTFDYLNDVVKVDEMEFSPAYAYEKAPDQDHFLGVQETR
                     ELFKKVFADGRRKKWRLNHSPLFLDFLEGKVDFQCTAWGIPSYSLFGWQKPCYLMSDGY
                     AKTYKELIETTDWDKYGRGKDPRCDNCMAHCGYEPTAVLATMGSLKESIRAAIEK"
     misc_feature    complement(9401..9416)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.99"
                     /tool="antismash"
     gene            complement(9420..10004)
                     /locus_tag="A37U_RS0113075"
     CDS             complement(9420..10004)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A37U_RS0113075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_020497096.1"
                     /transl_table=11
                     /translation="MTVTVLAPLRIEALSMRSAGAHVLRTGMGRARSLRAAPATTEPAV
                     VAGFGGALDGAVSAGDLVVGNCVRAEDGAEFALTEPERLAALLRESGLTVHLGPVVTTA
                     AIVHGARRSQLAATGALIADMESAHLLHRVTGPRAVIRAVVDTPRFPLSHPRTVTAGIA
                     AIRTLRRVGPGMRKWAEETTTLNTPAVDLEV"
     gene            complement(10001..11938)
                     /gene="shc"
                     /locus_tag="A37U_RS0113080"
     CDS             complement(10001..11938)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019809861.1"
                     /locus_tag="A37U_RS0113080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_240437581.1"
                     /sec_met_domain="T2TS (E-value: 5e-147, bitscore: 483.6,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEALLRAREHLLSLQNEQGWWKGKLRTNVTMDAEDLFLRQFLGI
                     RTEEQTEQTARWIRSQQAEDGTWATFPGGPAELSTTVEAYIALRLAGDDPQVRHMRLAR
                     DYILSQGGIPKTRIFTRFWLAMFGEWSWDDLPVLPPEMIFLPSWFPLNTYDWAAWARQT
                     VMALTVVSAMRPVRSLGIGITELYIDKPKRSIFALPTLPKLAELNPMRLVDARDKLRDD
                     FFSTAFNGLDWLLHRHEDSPVKPLRESALRQVGEWIIARQEADGGWGGIQPPWVYSIIA
                     LTLLGYQMDHPVLDKAINGLDGFTVWEETPDGTMRWFEACQSPVWDTALALNALLDAGI
                     PADNESVVTATDWLLAEQITVPGDWTVQRPGVECGGWAFEFANDIYPDTDDTSEIVLAL
                     NRVKHPQRQGAVRASIEKATTWLTAMRSKDGGWGAFDADNTQWLVNYVPFCDFGAVIDP
                     PSADVTAHIVEMYTALGMTHSRPARDGLRWLLDSQEEDGSWYGRWGANYIYGTGAVVPA
                     LIKSGISAGDNRIRRAVAWLYEKQNPDGGWGEDLRSYVDTTWSGKGTSTPSQTAWALLA
                     LLAAGERGPKADAGIRWLMSNQRADGGWDEEQFTGTGFPGDFYISYELYRLVFPINAIG
                     RYLGTDQPAS"
     gene            complement(12089..13096)
                     /locus_tag="A37U_RS0113085"
     CDS             complement(12089..13096)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005439219.1"
                     /locus_tag="A37U_RS0113085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_020497098.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.1e-61, bitscore:
                     200.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVMPSELTEARELVTPALRSAIDRLDGPTARVCRYHFGWEDGE
                     GKPSTPGGKTLRPALALLSAQAAGSRSELGVPAGAAVELVHNFSLLHDDVMDGDVERRH
                     RATAWRVFGVPAAILAGDAMLTVAVDTVREAYQPDRAVAVEKCLTTAVRRLIAGQSADV
                     SFESRADVTVEECVRMERDKTSALLACASSIGAVAAGADEATVHALDTFGEHLGIAFQM
                     VDDLLGIWGASEVTGKPALSDLTSRKKSVPVLAAMDSGTSAGDELRERYGNERETDVAL
                     LATLIEKAGGREWTSVQADEHVRSAIACLDEIDLPENTRAAFELTARFVTERDL"
     gene            complement(13176..14537)
                     /gene="hpnE"
                     /locus_tag="A37U_RS0113090"
     CDS             complement(13176..14537)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076662.1"
                     /locus_tag="A37U_RS0113090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_020497099.1"
                     /sec_met_domain="DAO (E-value: 2e-10, bitscore: 33.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAIVAGGGLAGLTAACSLVDRGWSVTVLEERARLGGATFSFTRE
                     GLVIDNGQHVLLRCYTEYLGWLRRLGVEHEIEMQPRFRIPVQRPGGNRYVLERTPGLPA
                     PLHLGPALARYGLLGLTDRLRVLRGVDELRKLELDNPALDEQRFGTWLRRAGQNDRTIE
                     ALWNLITVAALNTEADNAALSLCAMVFRTALLENADSADIGIPRVPLQRLHGEAAEKYL
                     RDRGASVRTDTPARRITPDADGFTVELDGERLEADRVVLAVPARKAAELAPKGSLRTPS
                     GYPEELGTSPILNLHVVYDREVLDEQMLAFVDSPVQWVFDRTAISGLTESSDDARKPSG
                     AQYLAVSLSAAEELIDEPTANLRKTFLPELSRVLPAAAAANVESFFVTRERHATFRQGP
                     GTAVMRANPASKVPGLVLAGAWTGTGWPDTMEGAVRSGLDAARLIGRPRLQEGT"
     gene            complement(14537..15391)
                     /gene="hpnD"
                     /locus_tag="A37U_RS0113095"
     CDS             complement(14537..15391)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005465126.1"
                     /locus_tag="A37U_RS0113095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_020497100.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.4e-59, bitscore:
                     194.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1e-65,
                     bitscore: 214.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLDEAYQRCEQITTEQARNFSYGIKLLPKPKRAALSAVYAFARR
                     IDDIGDGQDDAETKLAGLALAEQACADPAAFPEDPVLVAIADTRARTGIPMRAFEELIE
                     GCRADVLGTGYPDFEGLRHYCRCVAGSIGRLSLAVFGADRTPANDRLADSLGIALQLTN
                     ILRDIREDRINGRIYLPAEDLERFGCTLDIDADGALLDEHDALLALIEFEAARAQEWYA
                     EGMRLLGRLDRRSRACCAAMAGIYQRLLTNISLRPWQVLDRRVSLPGMEKAGVAARALA
                     GAF"
     gene            complement(15388..16215)
                     /gene="hpnC"
                     /locus_tag="A37U_RS43460"
     CDS             complement(15388..16215)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03464.1"
                     /locus_tag="A37U_RS43460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene synthase HpnC"
                     /protein_id="WP_157182805.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.2e-46,
                     bitscore: 152.3, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 3.1e-41, bitscore:
                     134.4, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTELRKVAGTENFPVALWFLPKKHRRHLMAIYVYARFVDYIGD
                     EAPGDRATLLRKVSRDLDELFAGSEPRDEVMRVLGETVREVGIPREPFDDLITANLTDQ
                     QVREYRTYEQLLDYCSYSANPVGNLVLYVFGNHTPANEKLSDRICTALQILEHLQDIAE
                     DAGNGRIYLPAQDRERFGVSTEELTRAPASRGLRALTAFEAQRAVRLLDEGEPLLRELR
                     GAGRIAVSGFLAGGRATAAAIAAANFDTIGSQVGPSKPRTAALALRSLVGGRG"
     gene            16482..17162
                     /locus_tag="A37U_RS48265"
     CDS             16482..17162
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024212.4"
                     /locus_tag="A37U_RS48265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_020497102.1"
                     /transl_table=11
                     /translation="MRKQPRKPRAHKQQAAPRKRARADTTPGKLARKQARADNKVARRR
                     AKAATRADKANKAAKKQQPIPSFLGPNATGTDSLELAERQLTLLVRTTAMLAQENTREA
                     PLDRSSYLLLCTLDKKGPSTISTLAAELCLAASTVTRQVATMCAAGLVSSAAHPNDRRA
                     RVITMESHGKELFVAERKRRRGVLRAITGSWTDDECEQLAELLSRLNTSLGQLFEGAPL
                     AYEL"
     gene            complement(17208..17879)
                     /locus_tag="A37U_RS0113110"
     CDS             complement(17208..17879)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013675772.1"
                     /locus_tag="A37U_RS0113110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VC0807 family protein"
                     /protein_id="WP_051111634.1"
                     /transl_table=11
                     /translation="MQTTHTTVHLPPVAALLRKAAVPLLESTLIPLGLFYLLFRLVGLD
                     GGLFAALGWSLLALGRRVVLRKKVPAVLWLTTTLLVVRTVIGFCTGSVFLYFLQPTAQN
                     FLITFALLATLPLKRPLLSKLADDFGVIPDTLSGHPHLQRVLKQISLLWALVFLVNGVS
                     TLFVLATQTVGNFLMVSTAGSYGVVGAAIAVSVLWIRRSMRNQGIALRLKLRWTGAHAA
                     A"
     misc_feature    complement(17643..17645)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18005..18946
                     /locus_tag="A37U_RS0113115"
     CDS             18005..18946
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417854.1"
                     /locus_tag="A37U_RS0113115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DMT family transporter"
                     /protein_id="WP_240437577.1"
                     /transl_table=11
                     /translation="MNTELVVAAPLAVLAAACIGLASAAQAGAAKQVEATGTLDPRLFK
                     RLVQKPLWLLGVGCTIAGLVLQLLALNFGPLILVQPIIITSLLFATVFYAWFGHTRIDG
                     IIMVGALLCCGGLAAFMLLARPTPGTSVPKDVWGPVPLAIVLVLVLGAGVLTANHVGRR
                     FKVLLLALCTGLAYGMTAALMKVITSQLQDGIGTIFAHPVLYLACALGPVGFLLAQNTF
                     QVGKLLSPALAVITVVDPIIGVLLGMQWFDEKVTVTPGTLIGELIAGAAVIGGISLLSR
                     RADHITASHAPQGDETADAGEVPGDTAPQSSH"
     misc_feature    18338..18340
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19068..19727)
                     /locus_tag="A37U_RS0113120"
     CDS             complement(19068..19727)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645885.1"
                     /locus_tag="A37U_RS0113120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_020497105.1"
                     /transl_table=11
                     /translation="MNPAATDAARTAVDGSGIDGSWYVDLTDFAKQTPWLHGIANGFTD
                     YGFVLFAALMVLAWWTARVRSPKIMAAALWSPIAVLLAYAISKYLVKPVVSELRPCRSI
                     PHVFTVAVCDPPSDFAFPSDHSVLAAAFAVSILLVHRGIGSAMIVLGLVMGFSRVYVGA
                     HYPHDVLGGYLLGAIVACSGFLAIRLLSGPIERLRENGRGTWLLGAPRRKPAHAAV"
     misc_feature    19775..19790
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.91"
                     /tool="antismash"
     misc_feature    complement(19776..19789)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
     gene            complement(19822..20817)
                     /locus_tag="A37U_RS0113125"
     CDS             complement(19822..20817)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024212.4"
                     /locus_tag="A37U_RS0113125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_020497106.1"
                     /transl_table=11
                     /translation="MDPGRGAGGSALRSHNMALLLRLITDEPGCSRAALAGRTGLTKAT
                     VSTLTAELIESGLVHETVRGGTDRPGRPATSLAPDPLGPVGIGLSLRAGKAVGYLADLG
                     GRVLARETRGIEGSEPRLARPVLRKLFDTATSAGRSVAGVTLAAPPGRHGPELDARLRA
                     ELAELGAPGIEAASGDELRYAAQAQARAHGSERLLYLGGETVLGAALLPEGSSGDLTHV
                     PVRPRGEPCPCGARGCLGRYVDPASVRERTGHAIEALSIALAPMLALTGWPPVLLGGWL
                     RAVPASTVGWRLGAQVHTARLGTEASLVGACTAALAHIREDPASWLAQWS"
     misc_feature    complement(20761..20763)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(20782..20784)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            20892..21977
                     /gene="ugpC"
                     /locus_tag="A37U_RS0113130"
     CDS             20892..21977
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ugpC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017987899.1"
                     /locus_tag="A37U_RS0113130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="WP_020497107.1"
                     /transl_table=11
                     /translation="MAEVAYVEASRVYPGNPPVRAVDKLSLQVNDGEFLVLVGPSGSGK
                     STALRMLAGLEEVNEGSITIGGRDVTKVQPKDRDIAMVFQSYALYPHMTVAENMGFALR
                     LKRVAKATVAEKVREAAEMLDLTAYLDRKPKALSGGQRQRVAMGRAIVREPSVFLMDEP
                     LSNLDAKLRVETRANIAALQQRLGTTTIYVTHDQVEAMTMGHRVAVLKDGLLQQCASPR
                     ELYERPENAFVAGFIGSPSMNLVTASVSADGAQLGGLDIPLLRGAETGAHDQVTLGLRP
                     ESLRLVGADEPGTELSVELVEELGADAYLHGTVAGDSNQRLVVRVDGRTPPRLGEKVRI
                     GVNAADQAHVFDPETGLRISD"
     gene            21997..25293
                     /locus_tag="A37U_RS0113135"
     CDS             21997..25293
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009078768.1"
                     /locus_tag="A37U_RS0113135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_026197180.1"
                     /transl_table=11
                     /translation="MSARRVPGYCTLCKSHCGSISVVDGNRLLAVEPLSEHPTGGALCA
                     KGRAMPELVASGERLLHPMRRTNPKDAEDPGWVRIGWDEALDEVAERLTAIAAESGPEA
                     VAFAVTTPSGTPMVDGHEWVNRLVRYYGSPNIIYATEICGWHKNFAHAFTFGKGIGTPD
                     YRHAELIVLWGHNPARTWLAQASAIAEARKDGATVVVIDPKRAGSGQQADTWMRIRPGT
                     DGALALGMINQLIQHGSYDEEFVRCWTNAPMLVGEDGELLGADGEFLVWDTVLEAPRGY
                     DTAHPLAEPRNVALRGSYTLPDGRTARPVFELLAEHAGDWSLDRVAETTWLEPAEIADF
                     YALLTKHQRVTYYTWTGVGQHTNATQTERAMGVLYALLGSYDRTGGIRWFDKLAQNPLG
                     PFSILGPEQQEKALGKAEMPLGPPAQGNVTARDFRRAALSGQPYPVRALIGFGANMVVS
                     QGAADENREALRALDFQVQCDMFVNPTAATADILLPVCAPPEREGLLIGFDNSAAGEEH
                     VQLRPRMVPPAGDSRSDYEIVLGLADRLGLRADFFDGDLDAGWNHQLAPLGLTVEQLRA
                     KPEGVRIPIEQRERKYATEASDGTVTGFATHTRRVELYATILREHGQPTLPTFTEPDEV
                     APGDEDFPFVLTTAKNGHYTHSSLRKLASLRRRSPDPCLELHPTLAAARGLAEGDWAIV
                     RTPDGQARLRVRFDESLHERVAIAEHGWWDNQPVAATPGLDALGTRTSNINAALSDRRR
                     DPVSGSVPLRAVACDIRRDDETSAGNWSGWREFRVTARVRTEVGALSLTLQPVDGGAVP
                     QFRPGQHIQVHAPELGTQRAYSLTNAYDSGSLRILVKHIGGRMSAHLHESAPEILELKA
                     PSGTFTLPFGGDRPVLCIGGGIGVTPFLGYLESLATGATAPPDLRVVYTRRNEQGAAPI
                     AERLRELAGRVPQARVHEYRTGAGIPRFGVTELDPEFLARKPLVYLCGPAAMMSELIEQ
                     FHAAGLDRFDIFSEEFFTEVEIPETLAPATVRFTRSGRELRWTKESGTLLDAAEAEGIP
                     LPSGCRTGACESCRITVRGGEFAHLSTVDNEPGSCLSCQAIPLSDLEIDA"
ORIGIN
        1 tgcggtgttg atggatgtgc ggatgccggg gctggacggg atcgcggcga ccgcgcggat
       61 cctcgccgag gggcatgccg cggtactcat gctgaccacc ttcgacctgg actcctacgt
      121 ctacggggcg ctgcgcgccg gggcgagcgg cttcctgctc aaatccgtgg acggggcccg
      181 gctcgccgat gcggtgcgca ccgtggccgc cggggaggcg atcatcgagc ccgccatcac
      241 caagcgactg ctgagcgcat tcgccacgag tgggccgccg gaggctccgg actggctgga
      301 cgcgctcacc gagcgggaac gggatgtgct ctcctgcctc ggcaagggct actcgaacgc
      361 gcagatctcc cgggagctct acgtcgccca ggccacggtg aaaacgcacg tgtccagcct
      421 gctcaccaag ctcgggctca gctcccgggt gcaggccgcg atccgagcac gggaggcggg
      481 actgtgaccg agcttcagca gaccgacccc cctcggctct cggtgttcag ctgggtggcc
      541 atccacgcgc tcggcacggt ggtcgtgatc gccaacctcg ccgcgaccca ggagaccgag
      601 ccctggatgt gggcggtcta cggctgcacg gtggcgctct ggccggtgta cctggtgctc
      661 gatttccacg actccgggct cacctgggtc ccgctcgcgc tcggtggcct ggtcaacgcg
      721 gtggtggacg ggttcgccgt ggatgtgacc gcgatgctgt tcgtcgcggt gttcatcgcc
      781 aggatgacct cgctgcccac gcttcgcttg tcggtggccc tcgccgcgcc cttcctggcc
      841 ggtgcgctcg tcgcgggcag cgaggcggtg ttcggcgagc tgcagttcga ccatgtgctc
      901 accgtggtca tgctcggcat cgtcggcttc ggcctgcgcc agtaccgcgc ccaggcgatg
      961 gccaccaggg aactgctcga gcagaccaga cgcacccagg ccgaacaggc ccgggccgcc
     1021 gcgctggacg agcgcacccg cattgcccgc gaactgcacg atgtgctcgc ccattcgctc
     1081 ggcgcgctcg gtgtacagct cgaggtcgcc gaggccatgc tgaccgaggg cggggacccg
     1141 caggcggcca ccgcgcgcgt ttcccgggcc cgcaggctcg ccgccgaggg gctcgccgag
     1201 gcccggtccg cggtggccgc gctgcgcggc gaggtgcccc cgctcgccga ggcgctgacc
     1261 gagatcaccg ccgcgcacgg gcgggatcac cagaccgaga ccggtttcac ctgcaccggg
     1321 acgccgcgcc cgctcgacgc cgcggtcacc gtcgccctgc tgcgcgtcgc cagggaggcg
     1381 ctgaccaacg ccgccaagca cgccccgggc gctccggtgg ccgtacgctt ggcattcgat
     1441 acggacacgg tcggcctcac ggtgcacgac agcggagcgg gcggagccgt ggacgcggcg
     1501 ggtggtgggc acgggctcac cgggatggcc gaacggctcg ccctcgccgg gggcagcctc
     1561 gaggcggggc cgtcggacgg cgcggaaggg aggggatgga cggtgcgggt cagcgttccg
     1621 gatcagcaag gggagcaggc gtgatcggcg tgctcgtggt ggacgaccag cacctcatgc
     1681 gggaggggct tgtcgcgctg ctcgggatgt gcgccgatat cgaggtcgtg ggtgaggccg
     1741 cggacgggaa cgccgccgtc gagttcgtgg cggaacacgg gcccgatgtg gtgctgatgg
     1801 acctgcgcat gcccgtgctc ggcggggccg aggcgacccg gcagatcctg gcgcgccggt
     1861 ccgggaccgc ggtgctcgtc ctgaccacct acgccgatga cgagtcgatc agcgaggcgc
     1921 tcggggccgg ggcgcgcggc tacctgacca aggacgccgg acgggacgag atcgcggccg
     1981 cggtgcgctc ggcggccgcc gggcacgcca ccttcgaccg caccgtttcg gaccggctgc
     2041 tcgcggcctt ttccggtgcg gcgagccagg agagttccgg caaacccgtg ggactgaccg
     2101 ggcgggaggc cgaagtgctc ggcctgatcg ccgatggcct gtcgaacgcg gacatcgccg
     2161 cacacctggt catcggggag accacggtga agacgcacat caacaacctg ttcgcgaaga
     2221 tcggcgtgcg cacccgagcc gaggcggtgc gctacgcctt tcgcatcggg atcaccggga
     2281 gttaggcgcg ggccgcaaca ggaatcatca agctcgcggg cggcgggcga agtagacata
     2341 ggcgggcggg aaattgcgca tcacggtgcg cgagacgacg gtttcctcga agttctcccg
     2401 cagttcccgg tgctggcggc gcgcgggcgg ggcccagcgg ctccaggcgt aggagaactg
     2461 ggtgaacgag ccgcgctcca cgagcgagtc cgcgaccagt tccaccagcg gctgcttgtc
     2521 cttgggccag tacgccgccc agggcagccc gctgatcacg acgtctgccc gcatgccgcg
     2581 cgcggcgagc acgtcgagca ggtcgtgggc gtcggcgcag accacatcca cgccgggata
     2641 gcgcgaggcg agcagccggg cccattcccg gttgcactcg atcgcgacat gggtaccgcg
     2701 cccgccgagc actcgctggg cggccgcggt gaacgccccg gtgcccgcgc cgagttccac
     2761 caccgccggg tcaccggtac ggggaatggg ggcgaccatc cgttcggcga ggtagctgga
     2821 gctgggcacg agtgaggccg tggtcatggg ggaacggaag aactgccgcg cgaaccgcca
     2881 ggcatcgcgc cccctcggcc ggttcaggtg cagcggggaa ccggcaccgt tcgccggatg
     2941 ggtcatggtc agcactcctg tcgggaacga acctgcgcct acgtccattc tcatgcagca
     3001 acatacccac tcgcgtccta ctgtgggtcg attggccggt gaattctcgg cgcgcgtccc
     3061 gggcagtgct cacatcccgg gcatcgggct catcaggaac tgcatggcca ccagcatcga
     3121 ggccatcccg agccccatca cggccaggct cacccggacg gcggcaccgt gttgtgctgc
     3181 ggtgggcccc cgtccgcgcg cccaccaccc ggcctgtgcc aggaaccacg ccgcgaacac
     3241 cacggtcagc caggcgaaac caggggtggg caccacgtac atgaaggcca tgccgagcag
     3301 gtcgatgacg cccatcgggg cgagcgtgat cagcccgtgc ccgcgcatcc gcccgctgac
     3361 cgccaggacg agcccggcga gggcacaggc caggaacaca ccctgggcca gcagcgacgg
     3421 gatcgtcagc cacggcaggt tcatcagcac catgcccgcg gccatgagca cgtgcccggc
     3481 atgccacacc gcgagcggcc ggtccactcc gcgcatatgg ctcaggtgca ccacgaggac
     3541 cgcggcgaac agcagtgcgg cgagcagggc cgcccaggtg ccgagcacgt gcccgctgga
     3601 caccacgagt acggccaccg caccgagtga gcccagcccg atacgggtga ttcggtgtga
     3661 cccgggagtc tttttgccca ccgtagtcga tcttgtcatc ggggccgtcc agtaacgtgc
     3721 acgtcagaac aggtttcttc actgggaagt aaagcagagt ggggtgctga cgtgtcagaa
     3781 gcgccttcgg tgaaacgagt actgatcgtt tccgcgaaca tgggtgaggg gcacaacgcg
     3841 accggccgcg cgctcgagga gcgggtgcac gtgctgtggc cggatgcgca ggtccggtgg
     3901 gtggacacgc tggacgcgat gggcaaggcc gtcgggcccg ccttccgctg gacttacgtg
     3961 accaatgtgg agtcgacgcc atggctctac gagttcttct acgactcgct gtggcaccgc
     4021 ccctggttcg cgcacgccgc gaaacggttc gtcgcggaat gggcgggacg ctcgctgcgc
     4081 ggggtgctgc gcgagttccg cccggatctg gtgttgccca cctatccgct cggcaccgcc
     4141 gggctgaact ggttgcgccg caggggagag ctctccgccc cggtcggcgc gtggatctcg
     4201 gatttcgccc cgcacccgtt ctgggtctat gaccgcatcg accgcaatgt ggtgatgcac
     4261 gatgtcgcga ccggcccggc gcgggtgtgc gtgcccaagg caccggtctc ggtgagcagg
     4321 cccccggtga ccggccggtt cgtgcccggt gaccggctcg ccgcgcgcaa gcggctcggt
     4381 cttccggtgg acgggttcgt ggccgtggtc tcctgcggat cgctcggctt cggctcggtt
     4441 gccgccgcgg tgcacgaact gctcagcgcc gacgagtcgg tgaccgtgct cgcggtgtgc
     4501 gggcgcaacg atgccttgcg cgccaaggtg aacgcggtca gtcccgggga tccgcggctg
     4561 atcgcctacg gctggaccga cgaggttccc gagctgctcg ccgcctgcga tgtgctcgtc
     4621 accaacgcgg gcggggcgac ctcccttgag gcgctggcct gtgaacgcgc ggtgctgatg
     4681 tatcagccca ttgccgcgca cgggaaggcc aatgcgcgcc tgatggccga tgccgggctg
     4741 gccattctgt gcccggatcg cggttcgctg accaggacgg tgcgcgaatt gctcgccgaa
     4801 ccgacgcggc tggccgccat cgaacgccgg gcccgcgagc acgtgcgtga tcaccccagc
     4861 ctggacgagg cgctcgtgga cctggccgga tccgtgcccg ccccgcaccg ggtgcgcgcc
     4921 caggactcga ttttccttta cgcggacggg aaaaaccatc ctcagcagct gggcgcggtg
     4981 ctggtcctgc atcccaagga ggacggcact ctgccggggc gcgcggaggc agaggtactg
     5041 ttcggcgcgc ttcccggtgg gcgcaaccgg atgcgccgcc gctggctgcg ccatccgcga
     5101 ctggtggacg accggatcgg ggacagcgac atccggctgt cccttgtgga catttccgaa
     5161 caggtcgccg agcagggcga ggaggcggca ctggacgccg cgctcgggga gttcttctcc
     5221 gcgcggctgg atccgtatca gtacgccggg cgggcacggc tggtcagcgg gctcgagggc
     5281 ggacgcgcgg cattcctggt gagctcgcac cattccttcg ccgacgggat ggcggtcacc
     5341 ggctcgctgg tgtccgcctc gcgcggaaac ccatggccgc aggagctcgc gccgttcgac
     5401 gagccggaga cggtcacccc gcgccagctg gtgcgcgggc tgtacacgct cgcccgcggc
     5461 ggcgcggtga aaccgaattc gctcaaccgt gcggtcacca ctcgggaacg ccgctaccgg
     5521 cgagcctggc tggaccagcc cgggttgaac gagatcgcga ccgaactcgg ggtcacggtc
     5581 ccggatgtgg tgctcggcct gctcgccgag gccctgcgcg ccgaggtgcc ggacacgcag
     5641 aacggcgccc ggctcaccgt tccgcagtcc acccgcagcg tgcgtacctt ccgctcggcg
     5701 ggcaaccaca ccggggcgat ccggctcgat ctcccggtcg ccgagatgga gctgccggag
     5761 cggatcaaac gcaccgccga ggcattgcgc gatgaggagg aatccggtgc gcccgcggcc
     5821 gcgcggctcg tggtgcgcgt catgggcggg ctgcccgcgc cgctgcaccg gatgctcgcg
     5881 gcaaacttca actccggcaa ctggttcaac atgatcgcct cgatcctgcc cggcgcgcgc
     5941 ggggtgctca aggtgcgtgg ctcgctgatc ggttcggtgt acccgatcct gccgctggcc
     6001 aaagggaccg cgttcgccgc cggattcatg ttgtgggcca aggaggtcac cgtgtgcatc
     6061 gccaccgatc cggacggggc cgagaccgcc gagcggttgt gcgcgcgcat cgaggccgag
     6121 tacgccgcgc tgcggatgag gaccgcatga gtgaagcttg cgagcgaatc gtggacctca
     6181 tgcgccgaaa gaggtcgaac acagtctcgc gaagcgaggc gaccgcatga gtgaagcttg
     6241 cgagcgaatc atggacctca tgcgccgaaa gaggtcgaac acagtctcgc gaagcgaggc
     6301 gaccgcatga gtatgaactg ggcgggtgcg cgggtactga tcaccggggc atcctccggg
     6361 atcggcgccg aactcgctcg gctgctggcg cgccgtggtg cgcacattct cgccgctggg
     6421 cgcaccggat ccgcgctgca cgggcacgag aacttcgcgg gcgatctcgc cgaaccgggt
     6481 gcctgcgtgg aactggcggc cgcggtcggc gatgtcgatg tgttcatcgg caacgccggg
     6541 ttcggatacg ccggggattt cgccgccatg ccaacggacc ggatcggcga actgatcacc
     6601 gtgaacctca cggcgaacat gctgctcacc cgcgcgctgc tgcccgggat gctggaccgg
     6661 gggcacggcg cgctcgccta catcacgagc atcgccggtg ccatggcggt ggccgaggag
     6721 gccgcgtatt ccggggcgaa ggcaggcatg gccaccttcg cggaaagcgt gcggctcgcc
     6781 gcgcggccga agggggtgcg ggtcaccacc gtcgttcccg gggtcgtgga caccgcgttc
     6841 ttcgaacggc gtggcgctgc ctatgaccgc tcccgcccgc gacccgttgc gccgcagcgg
     6901 gtcgcggagg ccactatcgc cgccatcgaa cgcggcaggg ccgaggtgtt cgtgccgtcc
     6961 tggctgcggt tcccggcccg gctcggcggg gccgcaccgg ggctggtgcg cgccctgcgg
     7021 agccgcttcg aatagccgct gctaaccggt gaacgccttg gtgaaatcga gtgggctctg
     7081 tgccaccccg ctgcaggtgg aggaggcgcg ggcggcggaa tcacaggctt tgtcgcggtt
     7141 cagcgaccag aaggaaagcc gccccacctg attcgatttc gcccattcgg cgaccgcttt
     7201 cgcgttgtcc atggtgagtg tggaattgtc gtcgttggtg ccgatcatcg gggtgatacc
     7261 gatattggca ttgctgtagc cggaatcgat gccctggatc tgtttgaggg tcgcctgggc
     7321 ggcgctggtc gcggccttgc ccatgtcctg gctgccctgg ttgtagtcca tcgccatgat
     7381 gttgacgatg tcgatgcgca ccccggcgtc tttggcggcc tgcacgggtt tcagcccgtc
     7441 ctgggtgagc ccgtccggca gtaccggcag ggtgaccgag atctcgaggt ccgggttact
     7501 cgctttgagt gctttcaccg ctttcatgtt ccgcgcggcg gccgcggtgt cgttctgggc
     7561 ggcgccctcg atgtcgaagt ccagctggtt caccttgtag gtgtcgatga tctgctggta
     7621 gcccttctgg atggcctgct gatcggtgca ggtccaggcg agtggcaggc ccgcggcgcc
     7681 accggtggag atgatcgggc tcgcgccttc ggatcgcgcc ttctcgatct ccccgtcgac
     7741 cttcggatcc ttgccgatcg gcagcgtgtc gccccagatc tggtcgcatc cggaaccggt
     7801 gacgaaagcg gcgctgaacg acttgagtcc ggccccggtt atcgcctggt ggagcatgtc
     7861 cacctgggaa ttcgacatgt cgacataggg ggcggcggtc gcgctcgccg tggtctgggc
     7921 gtcagcggtg aacgggacgg cgagcgcgca tccggtgact gcggcgacgg cggtggcaag
     7981 gaaggacttg cgggacatct gatctcctcg gctctgcgaa aggctcagga aaaagcgcca
     8041 cgtagcatcg cagcggccga gcttgatcgg taccgaccat cgtcgcttca caattgaccg
     8101 aacctcgtag gatgggttcg gcgataccag cgaacggaat cagcgaacga ggagaaaccc
     8161 atgatcgacc ggttcgaggc gggtaaggac accgtccagg agctcaccga gtcggcctcg
     8221 gcgcacatcg gcaatatcgc cacgatcgtc accggtgcgg tgcgcgatgt ggcccgggaa
     8281 acgggtgact ggctgaccga gctgatcacg atgccggagg cggcggcgcg ctcgacaagg
     8341 gacgagtgat cccccggtcc gagccgtacg tgcccggtcc gggggatccg ctgtctccgc
     8401 gttatttctc gatggccgcc cggatggact ccttgagcga gcccatggtg gccagcacgg
     8461 cggtcggttc gtagccgcag tgcgccatgc agttgtcgca gcgggggtcc ttgcccctgc
     8521 cgtatttgtc ccagtcggtc gtctcgatga gttccttgta ggtcttggcg tacccatcgg
     8581 acatcaggta gcagggtttc tgccacccga aaagggaata cgagggaatt ccccacgcgg
     8641 tgcactggaa atcgaccttg ccctcgagga aatcgaggaa cagcggcgag tggttgagcc
     8701 gccatttctt gcggcgaccg tccgcgaaca ccttcttgaa cagttcgcgg gtttcctgca
     8761 caccgaggaa gtggtcctgg tcgggagctt tctcgtaggc gtacgcgggg gagaattcca
     8821 tctcgtcgac cttgaccacg tcgttgaggt agtcgaaggt gtcgatgatg ctctgcgggg
     8881 tgtccgtgga gaagaaggtg gagttactgg tgacgcggaa tccgcgggac tgcagctcct
     8941 tgatcgcctc catcgcctcg tcgaagacgc cttccttgca caccgaggca tcgtgcgcat
     9001 cccgcagacc gtcgatgtga atggcccact ggaaatacgg cgagggtttg aaatcgaact
     9061 tgtcgatccg cttgcgcacc agcatggcgt tcgtgcacag ggtgacgaac ttcttgcgct
     9121 tgaccagttc gttgacgatg acgtcgatct gcgggtgcat cagcggttcg ccgccggaga
     9181 tggcgaccat gggcgcaccg gattcctcga tcgcgccgac tgcctgttcg accggcatcc
     9241 tgcgcttgag cacatcggcc gggtgctgga tcttgccgca ccccgcgcag gagaggttgc
     9301 acgcgaacag ggtttccagt tcgacgacga gcgggaattt cttcacgccc ctgattttgt
     9361 tcttgaaaat gtaggcacct acacgaagtg cctgtcgcac tggtacagcc atacgagttt
     9421 cagacctcca aatctaccgc gggagtgttg agggtcgtcg tttcctcggc ccatttgcgc
     9481 attcctggtc ccactctacg cagcgtacga atcgccgcga tgcccgcggt gacggtgcgc
     9541 gggtgggaca gcgggaaccg cggggtgtcg acgacggccc tgatgaccgc tcggggaccg
     9601 gtcacccggt gcagcaggtg cgcggattcc atatcggcga tgagcgcacc ggtcgcggcg
     9661 agttgggatc gccgcgcgcc gtgcacgatc gcggccgtgg tgacgaccgg tccgaggtgc
     9721 acggtgagtc ctgattcgcg cagcagcgcg gcgaggcgtt cgggctcggt gagcgcgaac
     9781 tcggccccgt cctcggcgcg cacgcagttg ccgacgacga ggtcgcctgc ggacacggca
     9841 ccgtcgaggg caccgccgaa cccggcgacg accgccggtt ccgtggtggc gggcgcggca
     9901 cgcagcgagc gcgccctgcc cattccggtg cgcagtacgt gcgcgcccgc gctgcgcatc
     9961 gaaagggctt cgatgcgcag cggggcgagc acggtaacgg tcatgatgca ggttggtccg
    10021 ttccgaggta gcggccgatc gcgttgatcg ggaagaccag ccggtagagc tcatagctga
    10081 tgtagaagtc gccggggaat ccggtcccgg tgaactgttc ctcgtcccag ccgccgtcgg
    10141 cgcgctggtt gctcatcagc cagcggatcc cggcgtccgc cttcggcccg cgctcaccgg
    10201 cggccagcag ggccagcagc gcccacgcgg tctgcgaggg ggtggaggtt cccttaccgc
    10261 tccaggtcgt gtccacatag gaccgcagat cctcgcccca gccgccgtcc gggttctgct
    10321 tctcgtacag ccaggcgacc gcgcgccgga tccggttgtc ccccgcggag atgccggact
    10381 tgatcagcgc gggaaccacg gcaccggtgc cgtagatgta gttcgcgccc cagcggccgt
    10441 accaggaacc gtcttcctcc tgggagtcga gcagccagcg cagcccgtcg cgtgccggcc
    10501 ggctgtgcgt catgcccagc gcggtgtaca tctccacgat gtgcgcggtg acatcggccg
    10561 acggcgggtc gatgacggcg ccgaaatcgc agaacggcac atagttgacc agccactggg
    10621 tgttgtccgc gtcgaacgcg ccccagccgc cgtccttgga ccgcatcgcg gtgagccagg
    10681 tagtcgcctt ctcgatggag gctcgtaccg cgccctgccg ctgcgggtgc ttgacccggt
    10741 tgagcgcgag cacgatctcc gaggtgtcgt cggtgtccgg gtagatgtcg ttggcgaact
    10801 cgaaggccca gccaccgcat tccacgccgg gccgctgcac cgtccagtca cccggcacgg
    10861 tgatctgctc ggcgagcagc cagtcggtcg cggtgaccac ggactcgttg tccgccggga
    10921 tacccgcgtc gagcagggcg ttgagcgcga gcgcggtgtc ccacaccggg gactggcagg
    10981 cctcgaacca gcgcatcgtg ccgtccgggg tctcctccca gacggtgaac ccgtcgagcc
    11041 cgttgatcgc cttgtccagc accgggtggt ccatctggta gccgagcagg gtcagcgcga
    11101 tgatcgagta cacccacggg ggctggatgc cgccccagcc gccgtcggcc tcctggcggg
    11161 cgatgatcca ctcgccgacc tggcgcagcg ccgattcgcg cagtggtttg accggggagt
    11221 cttcgtgccg gtgcagcagc cagtccagcc cgttgaacgc ggtgctgaag aagtcgtcgc
    11281 gcagcttgtc ccgggcgtcc accagccgca tcgggttgag ctcggcgagc ttgggcagtg
    11341 tgggcagcgc gaagatcgag cgtttcggct tgtcgatgta gagctcggtg atgccgatgc
    11401 ccagcgagcg caccgggcgc atggcgctga ccacggtgag cgccatgacc gtctggcgcg
    11461 cccatgccgc ccagtcgtag gtgttcagcg ggaaccagga gggcaggaag atcatctccg
    11521 gtggcagcac cgggaggtcg tcccaggacc attcgccgaa catcgcgagc cagaaccggg
    11581 tgaagatccg ggtcttcggg ataccgccct gggagaggat gtagtcccgc gccagccgca
    11641 tgtgccgtac ctgcgggtcg tccccggcga ggcggagcgc gatgtaggcc tcgaccgtgg
    11701 tggacagttc ggcgggtccg ccggggaaag tcgcccaggt gccgtcctcg gcttgctggg
    11761 agcggatcca gcgagcggtc tgctcggtct gctcctcggt gcggatcccg aggaactgac
    11821 gcaggaacag atcctcggca tccatcgtga cgttggtccg cagcttgcct ttccaccagc
    11881 cctgctcgtt ctgcagggag agcaggtgct cacgggcgcg caacagcgcc tcggtcacct
    11941 cggcttcgtc ggtggtcagc tcgctgtcga gtaccgtata gctcacgctg tctcctcgct
    12001 ggtgctcgtc gacaccgttc gcatagctgc tctgctgtct ggttcgctcg caagctcgct
    12061 cacgatcgct ggttcccctc tctgatgctc acaggtcacg ctccgttacg aatcgtgcgg
    12121 tcagttcgaa ggccgccctg gtgttctcgg gcagatcgat ctcgtccagg caggcgatcg
    12181 cggaccgcac gtgctcatcg gcctggacac tggtccattc ccgcccgccc gccttctcga
    12241 tcagcgtggc gagcagggcc acgtcggtct cccgctcgtt gccgtaccgc tcgcgcagtt
    12301 cgtcgcccgc gctggtgccg gaatccatgg cggcgagcac cgggaccgat ttcttccgcg
    12361 aggtcaggtc ggagagcgcc ggtttgccgg tcacctcgct cgcgccccag atcccgagca
    12421 ggtcgtcgac catctggaag gcgatcccga ggtgttcgcc gaacgtgtcg agcgcgtgca
    12481 cggtcgcctc gtccgcgccc gcggccaccg cgccgatgga actggcgcag gcgagcagcg
    12541 cggaggtctt gtcccgctcc atgcgcacgc attcctcgac ggtcacatcg gcgcgggatt
    12601 cgaagctgac atcggcgctc tgcccggcga tcagcctgcg caccgcggtc gtcaggcatt
    12661 tctcgacggc caccgcccgg tccggctgat aggcctcgcg caccgtgtcc acggcgacgg
    12721 tgagcatcgc gtccccggcc aggatcgccg cggggacccc gaagacccgc caggcggtcg
    12781 cgcggtgccg gcgctccacg tccccgtcca tcacatcgtc gtgcagcagc gagaagttgt
    12841 gcaccagttc gacggcggca ccggcgggga ccccgagttc ggagcgggat ccggccgcct
    12901 gcgcggaaag cagcgcgagc gcgggccgca gggtcttgcc ccctggcgtg ctcggtttgc
    12961 cctcgccgtc ctcccagccg aagtggtagc ggcagacgcg cgcggtggga ccgtcgagcc
    13021 ggtcgatggc cgaacgcaac gcgggggtca ccagctcacg cgcttcggtg agttcgctcg
    13081 gcatcaccgc ggtcatgaga ggacgccctt tccgagcatc gcagcgagcc acggcgagcg
    13141 aggagcgcgg gaaaggcgtc ctcgggccaa cacggtcatg tgccctcctg aagtctcggt
    13201 ctgccgatga ggcgcgccgc gtcgagcccg ctgcgcaccg ctccctccat cgtgtccggc
    13261 cacccggtac cggtccacgc ccccgcgagc accagccccg gcaccttgct cgccgggttc
    13321 gcgcgcatca ccgcggtccc cgggccctgg cggaatgtcg cgtgccgttc ccgggtgacg
    13381 aagaacgact cgacgttcgc cgcggcggcc gcgggaagca ccctgctcag ctcggggagg
    13441 aaagtcttgc gcaggttcgc ggtcggctcg tcgatgagtt cttccgcagc agacagtgac
    13501 acggcgaggt actgggcgcc actcggtttt cgcgcgtcgt cgctcgattc ggtgagtccg
    13561 gagatcgcgg tgcggtcgaa cacccactgc acgggggagt cgacgaaggc gagcatctgc
    13621 tcgtcgagca cttcccggtc gtagaccacg tgcaggttca ggatcggcga ggtgccgagc
    13681 tcctcgggat agccggacgg cgtgcgcagc gagcccttcg gggcgagctc ggccgccttg
    13741 cgcgcgggta ccgcgagcac gacccggtcc gcctcgagcc gttccccgtc gagttccacc
    13801 gtgaacccgt ccgcgtccgg ggtgatccgg cgcgccgggg tgtcggtgcg cacgctcgcg
    13861 ccccggtccc gcaggtactt ctccgcggcc tccccgtgca gccgctgcag cggaacacgg
    13921 gggatcccga tatctgccga gtccgcgttc tccagcagcg cggtgcggaa caccatggcg
    13981 cacagggaaa gcgcggcatt gtccgcttcg gtgttcagcg cggcgaccgt gatcaggttc
    14041 cacagcgcct cgatggtgcg gtcgttctgt cccgcgcggc gcagccaggt gccgaaccgc
    14101 tgctcgtcca gcgccgggtt gtccagttcg agcttgcgca gttcgtccac cccgcgcagt
    14161 acccggagcc ggtccgtgag gccgagcagt ccgtaccggg ccagtgcggg acccaggtgc
    14221 agcggggcgg gcagtccggg ggtgcgttcg agcacgtacc ggttcccgcc cgggcgctgc
    14281 accgggatgc ggaaccgggg ctgcatctcg atctcgtgtt ccaccccgag cctgcgcagc
    14341 cagccgaggt attcggtgta gcagcgcagc agcacgtgct ggccgttgtc gatcaccagt
    14401 ccttccctgg tgaacgagaa ggtggccccg ccgagccggg cccgttcctc gagcacggtg
    14461 accgaccagc cacggtccac cagcgaacag gccgccgtca gcccggcaag cccgccaccg
    14521 gccacgatcg cgcgcatcag aacgcacccg ccaaggcccg cgcggcgact cccgccttct
    14581 ccataccggg caacgagacc cgccggtcga gcacctgcca gggccgcagc gagatgttgg
    14641 tcagcagccg ctgatagatc ccggccatcg ccgcgcagca ggccctgctc ctgcggtcca
    14701 ggcggccgag cagccgcatc ccctcggcgt accactcctg ggcgcgggcc gcctcgaact
    14761 cgatgagggc gagcagcgcg tcgtgttcgt cgagcagggc gccgtccgcg tcgatgtcca
    14821 gggtgcaccc gaaccgttcg agatcttcgg ccggcagata gatccgcccg ttgatccggt
    14881 cctcgcggat gtcgcgcagg atgttggtca gctgcagggc gatgccgagc gaatcggcga
    14941 gccggtcgtt cgccggggtc cggtccgcgc cgaacaccgc gagggagagt cgcccgatcg
    15001 atccggcgac acaacggcag tagtgccgca gcccctcgaa gtccggataa ccggtgccga
    15061 gcacatccgc gcggcagcct tcgatcagtt cctcgaaggc gcgcatcggg atcccggtgc
    15121 gcgcccgggt gtccgcgatc gccaccagca ccgggtcctc gggaaaggcc gcgggatccg
    15181 cgcacgcctg ctcggcgagg gcgagaccgg cgagcttggt ctcggcgtcg tcctgcccgt
    15241 ccccgatgtc gtcgatgcgc ctggcgaagg cgtacaccgc ggagagcgcg gcacgcttgg
    15301 gtttgggcag cagcttgatg ccgtaggaga aattgcgagc ctgttcggtg gtgatctgct
    15361 cgcagcgctg ataagcctcg tcgagattca ccctcgtcct ccaacgaggc tgcgcagcgc
    15421 cagcgccgcg gtacgtggct tgctcgggcc gacctgcgaa ccgatcgtgt cgaagttcgc
    15481 cgccgcgatc gccgcggccg tcgcgcgccc gcccgcgagg aacccggaga ccgcgatccg
    15541 cccggccccg cgcagttccc tgagcagtgg ctctccctcg tccagcagtc gcaccgcgcg
    15601 ctgggcctcg aaggcggtca gcgcgcgcag cccgcgcgag gcgggtgccc tggtcagttc
    15661 ctcggtgctc accccgaacc gttcgcggtc ctgcgcgggc aggtagatcc ggccgttccc
    15721 ggcgtcctcg gcgatgtcct gcaggtgctc gaggatctgc agtgccgtgc agatcctgtc
    15781 ggagagcttc tcgttcgccg gcgtgtgatt gccgaacacg tacagcacca ggttgccgac
    15841 cgggttcgcg gagtaggagc agtagtcgag cagctgctcg taggtccggt actcgcgcac
    15901 ctgctgatcg gtgaggttcg cggtgatcag gtcgtcgaat ggttcgcggg ggatgccgac
    15961 ctcgcggacg gtttccccca gtacccgcat cacctcgtcg cgcggctcgc ttccggcgaa
    16021 caattcgtcg agatcgcggg aaaccttgcg cagcagggtg gcgcgatcgc cgggcgcctc
    16081 atcgccgatg tagtcgacga acctggcgta cacgtagatc gccatcagat gacgccggtg
    16141 cttcttcggg agaaaccaca gtgcgaccgg aaaattctcg gtccccgcga ccttgcggag
    16201 ctcggtggtg gacaccgccg gatgcggtgc tctgtgcgcc tgtgcggcgc ccgatcgctg
    16261 acgctggagg gccaatcggg tcatccttta ctgccgtcgt cggtcgccgc ggccgcttgt
    16321 ggctggcctt gccgaccacc gccgagttcg aggtcgtccg ggacatttcg cgattagttg
    16381 tgtcatacag ctacttttgc tgctaccgta ctcttcaccc tcggcttacg gtagttgtgg
    16441 gacatcactc gggcggctac aacccgacag ggactgcata ggtgaggaaa cagccacgaa
    16501 agccacgcgc gcacaagcag caggcggcgc cgcgcaagcg ggcccgagcg gacacaacgc
    16561 ccggaaagct cgcgcgcaag caggcgcgcg ccgacaacaa ggtcgcgcgg cggcgggcga
    16621 aagcggcgac ccgggctgac aaggcgaaca aggccgcgaa gaaacaacag cccattccgt
    16681 cgtttctcgg gccgaacgcc accggaaccg acagtctcga actggccgaa cggcagctga
    16741 ccctgctcgt ccgcaccacc gcgatgctcg cccaggagaa cacccgcgag gctccactgg
    16801 accgctcgag ctacttgttg ctgtgcaccc tggacaagaa ggggccctcg accatctcca
    16861 cgctggccgc cgagctgtgc ctcgccgcgt ccaccgtgac ccgccaggtc gccaccatgt
    16921 gcgcggccgg gctggtgtcc agtgcggccc atcccaacga ccggcgggcc cgggtcatca
    16981 ccatggagtc gcacggcaag gaactgttcg tggccgagcg caagcgccgc cgtggggtgc
    17041 ttcgcgcgat caccggcagc tggaccgacg acgagtgcga acagctcgcc gaactgctca
    17101 gcaggctgaa cacctcgctc ggccagctct tcgaaggggc cccgctcgcc tacgagctgt
    17161 gaaccgggga gcggcgaata ccccttcaca ggggtaccgc aggagggtca ggccgcggcg
    17221 tgcgcgcccg tccagcgcag tttcagccgc agcgcgatgc cctgattgcg catcgaacgg
    17281 cggatccaca gcaccgagac cgcgatggcc gcgccgacca caccgtacga gcccgcggtg
    17341 gagaccatca ggaagttgcc gaccgtctgg gtggcgagca cgaacagcgt gctgaccccg
    17401 ttgaccagga acaccagcgc ccacagcagc gagatctgct tcagcacgcg ctgcaggtgc
    17461 ggatgcccgg agagggtgtc cgggatcacc ccgaagtcgt cggcgagctt ggagagcagc
    17521 ggtcgcttca gcggtagcgt cgcgagcagg gcgaaggtga tcaggaagtt ctgcgcggtc
    17581 ggctgcagga agtagaggaa cacgcttccg gtgcagaacc cgatcaccgt tcggacgacg
    17641 agtaacgtgg tcgtcaacca caggacggcg ggaaccttct tgcggagcac gactcggcgc
    17701 ccgagcgcga gcagggacca gccgagcgcg gcgaacaggc caccgtccag tcccacgagg
    17761 cggaacagca ggtagaacaa accgagcggg atgagcgttg actcgaggag cggcaccgcc
    17821 gctttccgca gcagcgcggc gaccggaggg aggtgcaccg tcgtatgagt ggtctgcacg
    17881 cgctcagcca ccttgccaat cgggtcgact accgggttca gagtagggct ggccatagga
    17941 agtataaccg gacgcgtgaa attgcggtgg cggaccggtc ggatcgagag gaaaatagcg
    18001 cgtggtgaat accgaactgg tggtcgccgc gccactcgcc gtgctcgccg cggcgtgcat
    18061 cgggctcgcg agcgcggccc aggcgggcgc ggccaagcag gtggaagcga cggggacact
    18121 cgacccgcgc ctgttcaagc ggctcgtgca gaagccgctg tggctgctcg gggtcggttg
    18181 cacgatcgcg gggctggtgc tgcagctgct cgcgctgaac ttcggaccgt tgatcctggt
    18241 ccagcccatc atcattacct cactgctgtt cgccaccgtg ttctacgcat ggttcgggca
    18301 cacgcgcatc gacggcatca ttatggtcgg agccttgtta tgttgcggtg ggctcgcggc
    18361 gttcatgctg ctcgcgcgac ccacaccagg tacctccgtt cccaaggacg tgtggggccc
    18421 ggttccgttg gccatcgttc tggtactcgt tctcggtgcc ggggtactca ccgcgaacca
    18481 cgtcggccgc cggttcaagg tgctgctgct cgcgctgtgc accggtctcg cctacgggat
    18541 gaccgcggcg ctgatgaagg tcatcacctc gcagctgcag gacgggatcg gcacgatctt
    18601 cgcccacccg gtgctctatc tggcctgcgc gctcggcccg gtcggtttcc tgctcgcgca
    18661 gaacaccttc caggtcggca aactgctctc ccccgcgctc gccgtgatca ccgtggtgga
    18721 cccgatcatc ggcgtactgc tcgggatgca gtggttcgac gagaaggtca cggtcacccc
    18781 ggggacgctg atcggcgagc tcatcgcggg cgccgcggtc atcggcggga tcagcctgct
    18841 ctcccggcgc gcggaccaca tcaccgcgag ccatgcgccg cagggcgacg agacagcgga
    18901 cgcgggcgag gttcccggag acaccgcgcc ccagtcctcg cactgagccg ggttttcggc
    18961 ccggctcgcg cggcgggtcc ggtggcggaa cctcgggccc tgggcgacct ggccaggtat
    19021 tccgagacac cacgtcggtg ccgtcttcgc gaggaaacac ccccggatca gacggcggcg
    19081 tgtgccggtt tgcgccgggg cgcgccgagc agccaggtgc cgcgcccgtt ctcgcgtagt
    19141 cgttcgatcg gaccggaaag cagccggatc gccaggaaac cgctgcacgc gacgatcgcg
    19201 ccgagcaggt agccgccgag cacgtcgtgt gggtagtgcg cgccgacgta cacccgggag
    19261 aagcccatga ccaggccgag cacgatcatc gccgagccga taccgcggtg tacgagcagg
    19321 atcgagaccg cgaaagccgc cgcgagcacc gagtgatcgc tggggaaggc gaagtcgctc
    19381 ggcggatcac agaccgcgac ggtgaacacg tgcgggatcg agcggcacgg gcgcagctcg
    19441 ctcaccacgg gtttgacgag gtatttgctg atcgcgtagg ccagcagcac ggcgatcggg
    19501 gaccacagcg cggccgccat gatcttcggt gagcggaccc gcgcggtcca ccaggcgagc
    19561 accatcagcg cggcgaacag gacgaaaccg tagtcggtga aaccgttcgc gatcccgtgc
    19621 agccacggcg tctgctttgc gaagtcggtc aggtccacgt accaggagcc gtcgatcccc
    19681 gacccatcga ccgcggtgcg cgcggcgtcg gtggctgctg gattcatcgg tcctccgtgc
    19741 tcggaatggc gggtaggcgg gcgagcctag ccgatgtgat cggtgtcaag ccgtcgccct
    19801 gcgccccgtt catcgctaag gtcagctcca ctgcgccagc cagctcgccg ggtcttcccg
    19861 gatgtgcgcc agcgctgccg tgcaggcgcc gaccaggctt gcctcggtgc cgagccgggc
    19921 ggtgtgcacc tgcgcgccga gccgccagcc gacggtgctc gcgggtaccg cgcgcagcca
    19981 gccaccgagc agcaccgggg gccacccggt gagcgcgagc atcggggcta gcgcgatgct
    20041 cagcgcctcg atggcgtgcc cggttcgttc gcgcacgctc gccgggtcca cataacggcc
    20101 gaggcagccg cgagcgccgc acgggcaggg ttccccgcgc gggcgcaccg ggacatgggt
    20161 gaggtccccg gagctgcctt ccgggagcag ggccgcaccg agcacggtct cgccgccgag
    20221 gtagagcaac cgctcgctgc cgtgcgcccg cgcctgcgcc tgcgcggcat agcggagctc
    20281 gtcgccgctt gccgcctcga tgcccggggc gccgagttcg gcgagttcgg cgcgcaaccg
    20341 ggcgtcgagt tcgggaccgt gccttccggg cggagcagcc agggtcaccc cggccaccga
    20401 gcgccccgcg gatgtggccg tgtcgaacag tttgcgcagc accgggcgcg ccagccgcgg
    20461 ttcgctgccc tcgatgcccc tggtctccct ggccagcacc cggccgccga ggtcggcgag
    20521 ataaccgacg gccttgcccg cgcgcaggct cagcccgatc cccaccgggc cgagcgggtc
    20581 cggggcgagg ctcgtcgcgg ggcgccctgg ccggtcggtg ccgccgcgga ccgtttcgtg
    20641 caccagaccg gactcgatga gttcggcggt cagcgtggag accgtggcct tggtcagccc
    20701 ggtgcgcccg gccagcgcgg cccgcgaaca cccgggctca tcggtgatca accggagcag
    20761 taacgccatg ttgtggctgc gtaacgccga gccgccggcg ccgcgtccgg gatccatgtt
    20821 cgccagatta gttcattcgg tgaacgaaca aaacctggcg catccggtgg accaccggta
    20881 ggaaagcgcg catggcagag gtggcatacg tcgaagcgtc cagggtgtat cccggcaatc
    20941 cgcccgttcg ggcggtggac aaactgagcc tgcaggtcaa cgacggcgaa ttcctcgtgc
    21001 tcgtcggccc ctccggatcg gggaagtcga ccgcgctgcg catgctcgcc gggctcgagg
    21061 aggtcaacga gggcagcatc accatcggtg gccgggatgt caccaaggtg cagcccaagg
    21121 acagggacat cgccatggtg ttccagtcct atgcgctcta tccgcacatg accgtcgcgg
    21181 agaacatggg tttcgcgctg cggctcaagc gggtggccaa ggcgacggtc gcggagaagg
    21241 tccgcgaggc cgccgagatg ctcgacctga ccgcctacct ggaccgcaaa ccgaaggcgc
    21301 tctccggcgg gcagcggcaa cgagtcgcga tggggcgcgc gatcgtgcgc gaaccgagcg
    21361 tgttcctgat ggacgagcca ctgtccaatt tggacgccaa gctgcgggtg gagaccaggg
    21421 ccaatatcgc cgcgctgcag cagcggctcg gcaccacgac tatctacgtc acccacgacc
    21481 aggtcgaggc gatgaccatg ggtcaccggg tcgcggtgct caaggacggg ctgttgcaac
    21541 agtgtgcctc gccccgcgaa ctctatgagc gcccggagaa cgctttcgtc gccggcttca
    21601 tcggttcacc gagtatgaac ctggtcaccg cgagcgtttc cgcggacggc gcgcagctcg
    21661 gcggcctcga catcccgctg ctgcgcgggg cggagaccgg ggcgcacgat caggtcaccc
    21721 tcgggctgcg ccccgaatcg ctgcgcctgg tcggtgcgga cgaaccgggc acggaactgt
    21781 ccgtggaact ggtcgaagag ctcggtgcgg acgcctacct gcacggcacc gtggccggag
    21841 acagcaacca gcgcctcgtg gtccgggtgg acgggcgcac cccgccgcgg ctcggggaaa
    21901 aggtgcggat cggggtgaat gcggcggatc aggcgcacgt gttcgacccg gaaacagggc
    21961 ttcgcatcag cgactgagcc ggtatgctcg gatgatatga gtgctcggcg ggttcccggt
    22021 tactgtacgc tctgtaaatc gcactgtggc tcgatttccg tggtggacgg gaaccggctg
    22081 ctcgccgtgg aaccgctgtc cgagcacccg accggtggcg ccctgtgtgc caagggaagg
    22141 gcgatgccgg aactggtggc gagcggggag cggctgctgc atccgatgcg gcgtaccaat
    22201 ccgaaggacg ccgaggatcc cggctgggtg cggatcggct gggacgaggc actggacgag
    22261 gtcgcggagc ggctcaccgc gatcgccgcg gagtcgggac cggaagcggt cgccttcgcg
    22321 gtgaccacgc cgagtggcac gccgatggtg gacgggcacg agtgggtcaa ccgtctggtg
    22381 cggtactacg gcagcccgaa catcatctat gcgaccgaga tctgcggctg gcacaagaat
    22441 ttcgcgcacg ccttcacctt cggcaaggga atcggcaccc ccgactaccg gcacgccgag
    22501 ctgatcgtgc tgtgggggca caatccggca cgcacctggc tggcgcaggc gagcgcgatc
    22561 gccgaggctc gcaaggacgg ggcgaccgtc gtggtcatcg atccgaagcg ggcgggaagc
    22621 gggcaacagg cggacacctg gatgcggatc cggccgggga ccgacggagc gctggccctc
    22681 gggatgatca accagctgat ccagcacggg agctacgacg aggaattcgt gcgctgctgg
    22741 accaatgcgc cgatgctggt cggggaggac ggtgaactcc tcggcgcgga cggggaattc
    22801 ctggtgtggg acaccgtgct cgaggccccg cgcggttacg acaccgccca tccgctcgcc
    22861 gaaccgcgga atgtggctct gcgcgggagt tacacgctgc cggacggccg gaccgcgcgc
    22921 ccggtattcg aactgctcgc cgagcacgcg ggtgactgga gcctggaccg ggtcgccgag
    22981 accacctggc tggaaccggc cgagatcgcg gatttctacg cgctgctgac caaacaccag
    23041 cgggtcacct actacacctg gaccggggtc ggccagcaca ccaacgcgac ccagaccgaa
    23101 cgcgccatgg gcgtgctgta cgcgctgctc ggcagctacg accgcaccgg cggtatccgg
    23161 tggttcgaca aactcgcgca gaacccgctc gggccgttct cgatcctcgg ccccgagcag
    23221 caggagaagg ccctcggcaa ggccgagatg ccgctcggcc cgcccgcgca gggcaatgtc
    23281 accgcgcggg acttccggcg cgccgcgctt tccgggcagc cgtacccggt gcgggcgctg
    23341 atcggtttcg gcgcgaacat ggtggtctcc cagggtgccg cggacgagaa ccgggaagcc
    23401 ttgcgggcac tggatttcca ggtgcaatgc gatatgttcg tgaacccgac cgcggccacg
    23461 gcggacatcc tgttgccggt gtgcgcgccc ccggaacgcg agggcctgct gatcggcttc
    23521 gacaacagcg ccgccggtga ggaacacgtg cagctgcggc ccagaatggt gccaccggcc
    23581 ggggattcgc gttcggacta cgagatcgtg ctcggcctcg cggaccggct cggcctgcgc
    23641 gcggatttct tcgacgggga tctggacgcg ggctggaatc atcagctcgc cccgctcggg
    23701 ctcaccgtcg aacagctgcg tgccaagccc gagggggtgc gaatccccat cgagcagcgc
    23761 gagcgcaagt acgccaccga ggcgtcggac gggacggtga ccgggttcgc gacccatacc
    23821 cgccgtgtcg agttgtacgc cacgatcctg cgcgagcacg gtcagcccac gctgcccacg
    23881 ttcaccgaac cggacgaggt ggctcccggt gacgaggact tccccttcgt gctcaccacc
    23941 gcgaaaaacg gccactacac gcactcctcg ctgcgcaagc tcgcctcgct gcggcggcgt
    24001 tcacccgatc cctgcctgga acttcacccc acgctcgcgg cggcgcgcgg actcgccgag
    24061 ggggactggg cgatcgtgcg caccccggac gggcaggcgc ggttgcgggt gcgattcgat
    24121 gagagcctgc acgagcgggt ggcgatcgcc gaacacggct ggtgggacaa ccagccggtg
    24181 gccgcgacac cggggctgga cgcactcggc acccggacga gcaacatcaa cgccgccctc
    24241 tcggatcgcc gccgggatcc ggtgagtgga tcggtgccgt tgcgcgcggt cgcttgcgat
    24301 atccgcaggg acgacgagac ctcggcggga aactggtccg gttggcgcga attccgggtc
    24361 accgcgcggg tccgcaccga ggtgggcgcg ctttcgctga ccctgcaacc ggtcgacggc
    24421 ggtgccgtgc cgcagttccg ccccgggcag cacatccagg tgcacgcacc ggaactcggc
    24481 acccagcggg cgtactcgct caccaacgcc tacgattccg gctcgctgcg catcctggtc
    24541 aagcacatcg gcgggcggat gtcggcgcac ctgcacgaat ccgcgccgga gatcctcgaa
    24601 ctcaaggccc catcgggcac gttcaccctg ccgttcggcg gggaccggcc ggtgttgtgc
    24661 atcggcggcg ggatcggggt gacaccgttc ctcggctacc tcgagtcgct ggccaccggg
    24721 gccaccgcgc caccggatct gcgcgtggtc tacacccgca ggaacgagca gggcgcggcg
    24781 ccgatcgccg agcgcctgcg cgaactcgcc ggacgggtgc cgcaggcgcg ggtacacgaa
    24841 taccgcaccg gcgcggggat cccccggttc ggggtcaccg agctcgaccc ggagttcctg
    24901 gcgcgcaagc ccttggtcta tctgtgcggg cccgcggcga tgatgagtga gctcatcgag
    24961 cagttccacg cggccgggct ggaccggttc gacatcttca gcgaggagtt cttcaccgag
    25021 gtggagatcc cggaaacgct ggcccccgcc acggtccggt tcacccgcag tggccgggaa
    25081 ctgcgctgga ccaaggaatc cggcaccctg ctggacgccg cggaggcgga gggcatcccg
    25141 ctgccgagcg gatgccgcac cggggcctgc gaatcctgcc ggatcacggt gcgtggcggc
    25201 gaattcgccc acctgtccac tgtggacaac gaaccgggca gttgcctgag ctgccaggcg
    25261 attccgctct ccgacttgga gatcgacgcc tgagtacagg cagaaggttc gtattgtgcg
    25321 gacgttctgt gcacattgcc cgttgagcgg ggtgaccggg gcgaggatgg tctccgggca
    25381 tgactcgacg ccacagtgac gtgacgcgcg gggacctgat ccgtaggacg atgctcaccg
    25441 ggtccgcggt gagcgcgacc gcgaacgcgg cccaggaggt tccgccgccg aaagcccggc
    25501 cgcgggcacg cgaactggga atccgggtgg gatcgcggga aaccgggaaa cacaacgcga
    25561 tcaccgatgt ggacggggtc cgggtcgggc acaccacgct gatctccggg cagggtgaac
    25621 aggcggtgcg caccggggtc gcgatgctgg tgccgcacaa cggaaatccg ttcgaggacg
    25681 tgatcccggc cgggttccac tggctcaacg gtaacggaga gatgaccgga accgcgtggc
    25741 tgtgggaatc ggggctgctc tccttaccgg tctggatcac caacaccggc agcgtcgggg
    25801 tggtgcgcga cgcgctctac gcgctgcagg ccgaggaggg taaacagagc tggtcgctgc
    25861 ccgtggtcgc ggaaacctgg gatggcaagc tcaacgacac caacggccgg cacgtcacga
    25921 ccgcgcatgc gcgggccgcc taccgttccg cgcgatcggg accggtcgcc gagggcaatg
    25981 tcggcggcga gaccgggatg atctgccatg gtttcaaggg ggcatcggca cctcctcgcg
    26041 ggtgctggac ggcgcggacg gtggctggac ggtcggggtg ctcgtgcagg ccaatcacgg
    26101 caaacgtccg cggctgaccg tgcagggggt tccggtcggc gaacacatcg gcgcggatgc
    26161 ggttccgctt cccggagaat cgcaccaggg cgcgggggcg atcatcaccc tcgtc
//
