LOCUS       NZ_KB891311            22214 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces sp. ScaeMP-e10 B061DRAFT_scaffold_5.6, whole genome
            shotgun sequence.
ACCESSION   NZ_KB891311
VERSION     NZ_KB891311.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. ScaeMP-e10
  ORGANISM  Streptomyces sp. ScaeMP-e10
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 504042)
  AUTHORS   Stepanauskas,R., Sieracki,M., Masland,D., Poulton,N., Swan,B.,
            Garcia,M.M., Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C.,
            Tapia,R., Chen,A., Kyrpides,N., Mavromatis,K., Markowitz,V.,
            Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G., Pagani,I.,
            Pati,A., Goodwin,L., Nordberg,H.P., Cantor,M.N., Hua,S.X. and
            Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Improved High-Quality Draft of Streptomyces sp. ScaeMP-e10
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 504042)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
REFERENCE   3  (bases 1 to 504042)
  AUTHORS   Stepanauskas,R., Sieracki,M., Masland,D., Poulton,N., Swan,B.,
            Garcia,M.M., Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C.,
            Tapia,R., Chen,A., Kyrpides,N., Mavromatis,K., Markowitz,V.,
            Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G., Pagani,I.,
            Pati,A., Goodwin,L., Nordberg,H.P., Cantor,M.N., Hua,S.X. and
            Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. ScaeMP-e10
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            Isolation Site                    :: Gulf of Mexico
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 03:00:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,185
            CDSs (total)                      :: 7,109
            Genes (coding)                    :: 6,996
            CDSs (with protein)               :: 6,996
            Genes (RNA)                       :: 76
            rRNAs                             :: 6, 1 (5S, 16S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 45 of 113
            Pseudo Genes (incomplete)         :: 82 of 113
            Pseudo Genes (internal stop)      :: 12 of 113
            Pseudo Genes (multiple problems)  :: 23 of 113
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:33:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 404745
            Orig. end                         :: 426959
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB891311.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405355
            Source DNA and Organism available from Cameron  Currie
            (currie@bact.wisc.edu)
            Source DNA available from Cameron  Currie (currie@bact.wisc.edu)
            Organism available from Cameron  Currie (currie@bact.wisc.edu)
            Contacts: Cameron  Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22214
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22214
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22214
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12214](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12214)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            544..1617
                     /locus_tag="B061_RS37365"
                     /pseudo=""
     CDS             544..1617
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (21-266). E-value:
                     1.6e-27. Score: 88.6. Matches aSDomain:
                     nrpspksdomains_B061_RS37365_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956456.1"
                     /locus_tag="B061_RS37365"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /pseudo=""
                     /sec_met_domain="PF00561 (E-value: 1.6e-23, bitscore: 78.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.2e-16, bitscore:
                     54.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTFFAYDTTPLAYHLVGEGEPLICLPGGPMRASAYLGDLGGLSA
                     VRQLVLLDLRGTGESAAPEDPSTYRCDRLVADVEALREHLGLDRIDLLAHSAGANLAVL
                     YAARHPERLRSLTLITPSTRAAGIEVTDQDVREAAELRSGEPWYAEARAAQEALLAGGP
                     FAELWPAVRPLTYGRWDDTARAHAAASAGQTNPEARGRYDDGAYDPAATLPALRELAVP
                     VLVLAGEYDGHPSPDRATELAALFPYGEFTVQRGAGHFPWLDDPGALSRTVAAFLDPDV
                     RTVQAGGVRLA"
     aSDomain        607..1341
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B061_RS37365_Abhydrolase_1.1"
                     /evalue="1.60E-27"
                     /label="B061_RS37365_Abhydrolase_1.1"
                     /locus_tag="B061_RS37365"
                     /protein_end="266"
                     /protein_start="21"
                     /score="88.6"
                     /tool="antismash"
                     /translation="PLICLPGGPMRASAYLGDLGGLSAVRQLVLLDLRGTGESAAPEDP
                     STYRCDRLVADVEALREHLGLDRIDLLAHSAGANLAVLYAARHPERLRSLTLITPSTRA
                     AGIEVTDQDVREAAELRSGEPWYAEARAAQEALLAGGPFAELWPAVRPLTYGRWDDTAR
                     AHAAASAGQTNPEARGRYDDGAYDPAATLPALRELAVPVLVLAGEYDGHPSPDRATELA
                     ALFPYGEFTVQRGAGHFPWLDDP"
     gene            complement(1628..3250)
                     /locus_tag="B061_RS0129355"
     CDS             complement(1628..3250)
                     /NRPS_PKS="Domain: AMP-binding (8-437). E-value: 5.6e-67.
                     Score: 218.0. Matches aSDomain:
                     nrpspksdomains_B061_RS0129355_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491125.1"
                     /locus_tag="B061_RS0129355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_018515102.1"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-71, bitscore:
                     234.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESVVDVVPDREALLYVDHPGTGAERRLTYAELDAAA
                     NRIAHHLIGAGLRPGEHLGLHLYNGIEYLQTVLGALKARLVPVNVNYRYVEEELVYLYR
                     DADLAALVFDGEFDERVAAASAQAPALRHLVRVGSAAALPDLEAVPFTEAETSGSPSRG
                     FEPRSADDQFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGEPVKSPQELAERVAAG
                     GDGITFFPTPPLMHGTSTLTAFIGFNFGQRVVVHRKFAPEEVLRTIEREKVTSVSLVGD
                     AMLRPLIDALNGPLRGTDCSSLFSVSSSGAIMSDSVRAEFQALVPTVMLLNNFGSSESG
                     FNGTATADSGPERGFRVQVNARTAVVDPATYEPVAPGEVGRIAQRGHVPLGYYNDPAKT
                     ADTFFRKGDERWVLLGDMATVDAEGIVTVLGRGSQCINTGGEKVYPEEVEQALKSHPDV
                     YDALVAGVPDERWGSRVAAVLELREGAAALDLDAVQAHCRTRLAGYKIPRALVLTDRIQ
                     RSPSGKADYRWAKAVAAAAGTGT"
     aSDomain        complement(1940..3226)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B061_RS0129355_AMP-binding.1"
                     /evalue="5.60E-67"
                     /label="B061_RS0129355_AMP-binding.1"
                     /locus_tag="B061_RS0129355"
                     /protein_end="437"
                     /protein_start="8"
                     /score="218.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESVVDVVPDREALLYVDHPGTGAERRLTYAELDAAANRIAHHLI
                     GAGLRPGEHLGLHLYNGIEYLQTVLGALKARLVPVNVNYRYVEEELVYLYRDADLAALV
                     FDGEFDERVAAASAQAPALRHLVRVGSAAALPDLEAVPFTEAETSGSPSRGFEPRSADD
                     QFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGEPVKSPQELAERVAAGGDGITFFP
                     TPPLMHGTSTLTAFIGFNFGQRVVVHRKFAPEEVLRTIEREKVTSVSLVGDAMLRPLID
                     ALNGPLRGTDCSSLFSVSSSGAIMSDSVRAEFQALVPTVMLLNNFGSSESGFNGTATAD
                     SGPERGFRVQVNARTAVVDPATYEPVAPGEVGRIAQRGHVPLGYYNDPAKTADTFFRKG
                     DERWVLLGDMATVDAEGIVTVLGRGSQCIN"
     CDS_motif       complement(2042..2089)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B061_RS0129355_0002"
                     /evalue="3.10E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="B061_RS0129355"
                     /protein_end="403"
                     /protein_start="387"
                     /score="13.2"
                     /tool="antismash"
                     /translation="VPLGYYNDPAKTADTF"
     CDS_motif       complement(2684..2734)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B061_RS0129355_0001"
                     /evalue="3.00E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="B061_RS0129355"
                     /protein_end="189"
                     /protein_start="172"
                     /score="19.8"
                     /tool="antismash"
                     /translation="FIIYTGGTTGMPKGVMW"
     misc_feature    3328..3341
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(3344..3358)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.75"
                     /tool="antismash"
     misc_feature    complement(3346..3362)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.71"
                     /tool="antismash"
     misc_feature    complement(3348..3363)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.75"
                     /tool="antismash"
     gene            3417..4262
                     /locus_tag="B061_RS0129360"
     CDS             3417..4262
                     /NRPS_PKS="Domain: ECH (24-273). E-value: 2.6e-53. Score:
                     172.8. Matches aSDomain:
                     nrpspksdomains_B061_RS0129360_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572848.1"
                     /locus_tag="B061_RS0129360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_051104721.1"
                     /transl_table=11
                     /translation="MGGTEDLGTEHVGTEHVGTEHLTVERRGATLVLTLNRPQARNALS
                     LPMLVGLYDGWLAADADDEVRSVVLTGAGGAFCSGMDLKALAGGGMEGEEYRERMTADP
                     DLHWKAMLRHHRPRKPVIAAVEGPCVAGGTEILQGTDIRIAGEGATFGLFEVRRGLFPI
                     GGSTVRLPRQIPRTHALEMLLTGRPYTADEAASIGLIGRVVPDGTALEEALAVAERINA
                     CGPLAVEAVKASVYEGAELTESEALAAELKRGWPVFATEDAKEGARAFAEKRPPVYRRA
                     "
     aSDomain        3489..4235
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B061_RS0129360_ECH.1"
                     /evalue="2.60E-53"
                     /label="B061_RS0129360_ECH.1"
                     /locus_tag="B061_RS0129360"
                     /protein_end="273"
                     /protein_start="24"
                     /score="172.8"
                     /tool="antismash"
                     /translation="ERRGATLVLTLNRPQARNALSLPMLVGLYDGWLAADADDEVRSVV
                     LTGAGGAFCSGMDLKALAGGGMEGEEYRERMTADPDLHWKAMLRHHRPRKPVIAAVEGP
                     CVAGGTEILQGTDIRIAGEGATFGLFEVRRGLFPIGGSTVRLPRQIPRTHALEMLLTGR
                     PYTADEAASIGLIGRVVPDGTALEEALAVAERINACGPLAVEAVKASVYEGAELTESEA
                     LAAELKRGWPVFATEDAKEGARAFAEK"
     gene            4308..5255
                     /locus_tag="B061_RS0129365"
     CDS             4308..5255
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382254.1"
                     /locus_tag="B061_RS0129365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_018515104.1"
                     /transl_table=11
                     /translation="MTDVLSAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRADDGTV
                     LVPPVEYDPVTAGELRELVEVAATGTVTTWAWNPSPRRDQPLETPFAWVLVRLDGAATA
                     LLHALDAPGPDAVHTGMRVRIRWAVTRTGAITDIACFEPYDGEPGPAEPAPHDGEFADP
                     VTGIVAPARLDYVHSPGRAQSAYLKALAGHRTVGERCPACRKVYVPPRGACPTCGIATA
                     EQVEVGPRGTVTTFCIVNIKAKNLDIEVPYVYAHIALDGADLALHGRIAGIPYDQVRMG
                     LRVEPVWAEGAAHPDHYRPTGEPDADYDTYKELV"
     gene            5256..6308
                     /locus_tag="B061_RS0129370"
     CDS             5256..6308
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550730.1"
                     /locus_tag="B061_RS0129370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_018515105.1"
                     /transl_table=11
                     /translation="MRDVAIVAFAQTVHRRRTDELSEVDLLMPVLHEVLGATGLKANEI
                     GFTCSGSADYLAGRAFSFTMALDGVGAHPPISESHVEMDGAWALYEAWVKIMTGEADTA
                     LVYSYGKSSPGEVRDVLTRQLDPYYLAPLWPDSVSLAALQAQALIDAGDTDEAALASIA
                     ARSRTDATANPYAQLTGDVPAGDHLVHPLRIGDCPPIGDGAAAVILAAGDTARALCARP
                     AWIRGIDHRIEAHSLGVRDLTDSPSTRLAAQHAGAFERPLDTAELHAPFTSQEVVLRKA
                     LGLGDDTRINPSGGALAANPIMAAGLIRLGEAAARIHRGESDRALAHATSGPCLQQNLV
                     AVLEGESAHV"
     gene            6301..7467
                     /locus_tag="B061_RS0129375"
     CDS             6301..7467
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971158.1"
                     /locus_tag="B061_RS0129375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_026242032.1"
                     /transl_table=11
                     /translation="MSKEPVAVVGIGQTKHVAARHDVSIAGLVREAAVRALEDAGLTWS
                     DIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVAANLVAAR
                     VHRTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYMRRTGAPDTVGS
                     LVAYKDRRNALKNPYAHIHDADITLEKVQASPMLWDPIRYSETCPSSDGACAMVLTDRE
                     GASRAPHPPAWVHGGAMRSEPTLFAGKDFVSPQAGKDCAADVYRQARITDPRREIDAVE
                     MYVPFSWYEPMWLENLGFAGEGEGWKLTEAGVTELDGDLPVNPSGGVLSTNPIGASGMI
                     RFAEAALQVRGRAGEHQIDGATRAVGHAYGGGAQFFAMWLVGSQPPPG"
     gene            complement(7493..9061)
                     /locus_tag="B061_RS0129380"
     CDS             complement(7493..9061)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606691.1"
                     /locus_tag="B061_RS0129380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018515107.1"
                     /transl_table=11
                     /translation="MTVEGTVSGLEERVVGRAWMVRLDPADRGGAAVRVSCGRPACAPQ
                     VLPSAAVGRTAAVAHLATHLRAAPGPRPQASCACRAEECHTHVRADGPRDRAPALRCGG
                     PVVLAVINDRQGRWWQALECCARCAAAHPSAKIVATAPAAPARAAAGPAPAAGARGAAG
                     PPPVPVGPHFSHAASSPAPVPVPRAAPVPRTKPRRNRRTGKIAQRFVPHDLHPIALRDE
                     LIELGNLFRAYQERPEPDLEQLAELHSRKAKAFRTWAEVTGETELRLDAERAEQAAAAA
                     LLQHQQRTGQSPVGEGEVTNRLLPGLTQWEHARTVLAYVAEHTPLPGPEARLMAVMLTL
                     RSALTGTGNLVGQDVRGLPLTEPEELIGRLVDSGWLSIPGTADDLLESRPESPTPITIP
                     SLMPDDDGQGPFDFGRKTRPKLSGWAQRVVGDKKLRKKKTGAATRLLALALAVRTTTDG
                     RLGAEGEGVDLAVLTSWCAVEPDELESLVEQLTVADWLEEAAVTDGRLTGRLAERVLQV
                     SCPLP"
     misc_feature    complement(9338..9348)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            9351..9851
                     /locus_tag="B061_RS0129385"
     CDS             9351..9851
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="B061_RS0129385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_026242033.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLYGGRGPAMIIGNLPAGSPARETEDGQVPFEVAQLLLALENDEPIEVVSSEDV
                     PVMQGDNLLIVRRVKLSESRIACVQFDRSDGVLVTIASWDRPITDDLYTLLKPLPAELF
                     QQG"
     gene            complement(10001..12214)
                     /locus_tag="B061_RS0129390"
     CDS             complement(10001..12214)
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956438.1"
                     /locus_tag="B061_RS0129390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="terpene synthase family protein"
                     /protein_id="WP_018515109.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-86, bitscore: 286.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFSLPDFYVPYPARLNPHVEAARTHTRQWARGMGMLEGSGIW
                     EEKDLEAHDYALLCAYTHPDCSAEALSLVTDWYVWVFFFDDHFLELFKRTPDREGAKRY
                     LDRLPAFMPMERGAATPEPENPVEAGLADLWTRTVPAMSDAWRARFAESTENLLNESMW
                     ELSNINEGRIANPVEYIEMRRKVGGAPWSAGLVEYAAGAEVPAQVAGARPLRVLRDAFS
                     DGVHLRNDLFSYQREVEEEGENSNGVLVLEKFLGCSTQEAAEAVNDLLTSRLQQFENTV
                     LTELGPLCAEKGLDPTQTASVLAYVKGLQDWQSGGHEWHMRSSRYMNGGGAGEAVAGFG
                     MSAASIKFTLRSETARARSHSHLPFQHVGPSLIPDLELPFGTTLSPHLEGARVRLVDWA
                     RRMGILEAQPGVPGSHIWDEERIVAIDLPLCAAGIHPDASPEELDISSAWLAWGTYGDD
                     WFPVVHGRSRDLAGARLANERLSLFMPLDGEAIPEPVNALERSLGDLWRRTAEPMDLGA
                     RRTFRTAIESMTESWLWELANQAQNRIPDPVDYVEMRRDTFGSNLTMSLCRLGHGRTVP
                     EAVYRSGPMQSLENAAADYACLLNDLFSYQKEIEYEGEVHNGVLVVQNFFGVDYPTGVA
                     IVHDLMKSRLRQFLHVAEVELPVLYDDFGLDAEAREVLAGYVQELKHWLAGILIWHRGC
                     RRYREEDLRRGHGAPWHLSGPTGLGTSAAQVTRLMAELAGSRA"
     misc_feature    12318..12332
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.22"
                     /tool="antismash"
     gene            complement(12388..13101)
                     /locus_tag="B061_RS0129395"
     CDS             complement(12388..13101)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971163.1"
                     /locus_tag="B061_RS0129395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_018515110.1"
                     /transl_table=11
                     /translation="MPRTIRITRSHKLATAVLVAAGSVTAIAATGGQSDAQPAAAKTSI
                     AAEKVAGASTAKEAAAKKAAQETAAKKAAADAAAAKKAVAERKAAAEKAVADRKAEAKK
                     SAEKARSEKQAANRSTERKAVAAPKQYKNNLDGWIRESLDIMKKKNIPGSYEGLHRNIM
                     RESSGNPNAVNDWDINAQNGIPSKGLLQVIQPTFDAYHVNGTEKKLTDPVANITAAANY
                     AADKYGSIDNVDSAY"
     misc_feature    13422..13432
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    13537..13546
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(13608..14744)
                     /locus_tag="B061_RS0129400"
     CDS             complement(13608..14744)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="B061_RS0129400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_026242034.1"
                     /sec_met_domain="APH (E-value: 1.5e-18, bitscore: 62.2,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRPLRPMGTGGGPYLAPHAGAPAQGLGRTRRAAG
                     PGAGPLSGRIDLSGPQGAQVRMAIASVQRICPEFNPVQVLRRSGRSVLIVGTTGRATAV
                     AKCLLDHSPAWTERFQHEIAAYRAFVRHRPPVRVPRLIAADPENCTLVIERMPGRVAAL
                     TRHPAEAPPRADIRAALGAIARVNAWRPPPGLFEAPLDYASRISRYHELGLFTDRDLGD
                     LQKLLHGLAQAGGRQGMGQFCHGDALLSNILLSPTGPVLVDWEHAGWYLPGYDLATLWA
                     VLGDAPVARRQISQLAQARGPAARDAFLVNLMLVLTREIRNYETAVQRTMREAPAVGAG
                     QDRPGALSSGEEQRLLLRRLHDDCAMARRAVRAAVGTR"
     misc_feature    complement(14421..14423)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14976..16472
                     /locus_tag="B061_RS0129405"
     CDS             14976..16472
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606686.1"
                     /locus_tag="B061_RS0129405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018515112.1"
                     /transl_table=11
                     /translation="MTGEPNTRLSDLFGLAGWSKGELARMVNRQAAAMGHPQLATDTSR
                     VRRWIDMGESPRDPVPEVLAALFTERLGRVVTIEDLGFGRRGRVGKRRDAGKEHDPDQL
                     PWAPERTAAVLTEFTGMDLMLNRRGMVGAGAALAAGSTIAGPMYDWLRSSPASAADAPR
                     ANDPQHADPAGFDRYEAAPVGSEEIEALEHSVEVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYRHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLAKSGSGDETLPRTQAMLRTIEAWAQAAMGKGQA
                     MRRTLGEAEELFVSDKGDVPAPSWMQMFDEADLHGMQALAFRTLAEHDPAAAVIAQHHA
                     KQALELRVNGRQRSKLFDHISLASACFIADDPEQGDRYARLALVSMGETSSHRTWDRLR
                     EMYRLTGQFEGYAKIQDLRKQIELSLPQSPVAHKSRGTQA"
     misc_feature    15018..15033
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            complement(16566..17990)
                     /locus_tag="B061_RS0129410"
     CDS             complement(16566..17990)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956434.1"
                     /locus_tag="B061_RS0129410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_026242035.1"
                     /transl_table=11
                     /translation="MPSHLFADRPAPQPPAHDAVDALIHRARRLRGDVEAVGRNTAVTD
                     EDDPQARWQRALCDLAVQYLDNLDQHLGQLKAGPPAQRSADRDDRVSTDGASAGSSANR
                     VGSAEWNLLTDEVSWSEELYEIFGRPPGSPPLSLDDLPSVLFPDDQPKLTSMVTGCLVD
                     GQPMDGEFRIVRPDGQVRTLHMTGEPVLDSEGCTASMWAVLRDVGELRRGEESVSRNRD
                     SARRDEPVERPRHRTATEVQETALPPWRGSLLLPAGGPGALDIAAHHLPSAAGGLIGGD
                     WYDAMELPDGRTLLSVGDLSGHGLPATSALAMMLGALRGMAVAGIEPGALMGHLDHLLE
                     TSVRPALGSALCCRFDPTTGLLSWAQAGHPAPLLFRDGTGRRLPPPEGALLGAASRIAY
                     EQDEVRLLPGDVLVLHTDGLTRRGDRGAVPEQLLALAHRFAQARDAQECVRGVVEEFGG
                     AERLDDACVLVARIGA"
     gene            18263..19111
                     /locus_tag="B061_RS0129415"
     CDS             18263..19111
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606684.1"
                     /locus_tag="B061_RS0129415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphotransferase"
                     /protein_id="WP_018515114.1"
                     /sec_met_domain="APH (E-value: 3.4e-11, bitscore: 38.2,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEQPSVILPPWSVLDAFGVRGIPEPLTGGQGRSVRVGRAVLKPA
                     EGTEGESEWAASVFERLPRGAGFRVPRPLRSAGGDAVVEGWTAAEFTEGRPGPSRQWPG
                     VVATGRAFHAALRELPRPAFLDRRTHPWAVADRVAWGEEETAVVPELAEPFARLLSLRR
                     PVEAAAQIVHGDLTGNVLFAPGQDPVVIDFSPYWRPPLYAEAVVIGDGLLWYEPAPGLL
                     VGGGGDPRWRQMLIRALIFRLVALSGLVGPSWRAGEKEAARLLAATEAVERGTYEGRAQ
                     L"
     misc_feature    complement(19180..19194)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.29"
                     /tool="antismash"
     misc_feature    19181..19192
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.7"
                     /tool="antismash"
     misc_feature    complement(19181..19196)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.65"
                     /tool="antismash"
     gene            19240..19404
                     /gene="rpmG"
                     /locus_tag="B061_RS0129420"
     CDS             19240..19404
                     /GO_component="GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpmG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192346.1"
                     /locus_tag="B061_RS0129420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="50S ribosomal protein L33"
                     /protein_id="WP_018515115.1"
                     /transl_table=11
                     /translation="MARNELRPVVTLRSTAGTGSSYVTRKNRRNTPDRLELRKFDAAAG
                     QHVLFRETR"
     gene            19481..19741
                     /locus_tag="B061_RS0129425"
     CDS             19481..19741
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606682.1"
                     /locus_tag="B061_RS0129425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="WP_018515116.1"
                     /transl_table=11
                     /translation="MKPRIHPVSRPVVFRDRAADVAFLTRSTADSGARVTWEDGNTYPV
                     IDVETSSASHPFYTGGRQALDTAGRVERFRRRYGTDEASRS"
     gene            complement(19966..20601)
                     /locus_tag="B061_RS0129430"
     CDS             complement(19966..20601)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524490.1"
                     /locus_tag="B061_RS0129430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YoaK family protein"
                     /protein_id="WP_026242036.1"
                     /transl_table=11
                     /translation="MLLSAASGAADAFAFLCVGQVFAGVMTGNLVLLGASAAGAGEDGV
                     ALRVVTALAAYACGVAAGTLMAGLPLGLTLLAESVLLGVAAALWGFGLVASYGDRLGLL
                     ALVSLAMGVQGRVRVTPTNYFTGTLTSLAGRAAARRLEPGDGWVLGRLGAVVAGAALAA
                     LTERWWSPGAALGAVVLVAGATVLETGWRGGRNTGKPRPDRGNPAGAA"
     gene            complement(20767..21267)
                     /locus_tag="B061_RS0129435"
     CDS             complement(20767..21267)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018515118.1"
                     /locus_tag="B061_RS0129435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_018515118.1"
                     /transl_table=11
                     /translation="MSAREKKDQLAETDRLRQEGRAGEARERLLALTAEFPDDAEVAYR
                     TAWVHDVLGLETEAVAYYERSVAGTGLDAEDRRGALLGLGSTYRVLGRYGQAVETLRRG
                     VEEFPDDGALQTFLAMALFNTEEHHEAMQLLLRVVASNSEDRHVQQYRPAIEHYAKDLH
                     ETM"
     misc_feature    21225..21239
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            21366..22151
                     /locus_tag="B061_RS0129440"
     CDS             21366..22151
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382265.1"
                     /locus_tag="B061_RS0129440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VanZ family protein"
                     /protein_id="WP_106435373.1"
                     /transl_table=11
                     /translation="MTAETNPRTRHGAWARVLLRVTVLTVVLLGLVAFSILLAKVTLTP
                     SPASEDIVTSNLQPGRSLRQYAEDYTFLAACKQAGGNVLLGVPFGLLLPFLVPRRLRMI
                     SMTLLTAAAMVLVELVQGALVTGRAFDIDDVILNTSGALLGYLLLGRRISHSYHVRAHT
                     PRAEAVEPEAAERETPSRTKARTATKTGAKTKTGATKTGTTKAGTPARGTTKAKEPVET
                     GARTGSTRLPKARGSSGRRTAGAAQPGSGRALMDRLRRR"
ORIGIN
        1 cggccgcccg ccgcgcggat cgaccgggcg accacatccg cccaggtgtc caggtcccgc
       61 tcggtgtagc cgacgacggt cgggcggccg gtcgtgccgc tggaggcgtg gatgcgccgg
      121 acgtccgcct ccggcacggc gaacatcccg aaggggtagt tgtcgcgcag gtcggccttg
      181 gcggtgaagg ggaagcggga gagggcggcg agcgtacggc agtcctcggg ccgcagcccg
      241 gccgcgtcga acgccgcccg gtagaacggc acgttctcgt aggcgtgacg cagggtcgta
      301 cggagccgtt cgatctggag ggcctccaga tcggcgcggc tcagctgttc cgccgcgtcc
      361 agcatggctg tcataaggcc cttcctctcc cgaaccgggc gaccgatcat tcggtcgatc
      421 ttcctgggag cagtaattca ggaggccggg ggcgctggca agaggggcgc acggacccgt
      481 tccggatcgg ctcgcagcgg agcccggtgc gaacgtctgc gtgttcctgt ttggatggac
      541 ggcatgccga ccttctttgc gtacgacacc accccgctcg cctaccacct ggtgggggag
      601 ggtgagccgc tgatctgcct gcccggcggg ccgatgcggg cgagcgcgta cctcggcgac
      661 ctcggcgggc tctccgccgt acggcagctg gtcctgctgg acctgcgcgg aacgggggag
      721 tccgccgcac ccgaggaccc ctcgacctac cgctgcgacc ggctcgtggc cgacgtggag
      781 gcgctgcgcg agcacctcgg cctggaccgg atcgacctgc tggcccactc ggcgggcgcg
      841 aatctggccg tgctgtacgc cgcccggcac ccggagcggc tgcgcagcct gaccctcatc
      901 accccctcca cccgggccgc cggcatcgag gtgaccgacc aggatgtgcg cgaggccgcc
      961 gagctgcgca gcggcgaacc ctggtacgcc gaggcccggg ccgcccagga ggcgctgctc
     1021 gccggcgggc ccttcgccga gctgtggccc gccgtccggc cgctcaccta cggccgctgg
     1081 gacgacacgg cccgggccca cgccgccgcc tccgccgggc agaccaaccc cgaggcgcgc
     1141 ggccgctacg acgacggcgc gtacgacccc gctgccaccc ttcccgccct gcgcgagctg
     1201 gccgtgccgg tgctcgtcct cgcgggggag tacgacggcc acccgagccc ggaccgggcg
     1261 acggagctgg ccgcactttt cccgtacggc gagttcaccg tccagcgggg cgcggggcac
     1321 ttcccgtggc tcgacgaccc gggcgccctt tcccgtaccg tggcggcctt cctcgacccg
     1381 gacgtccgca ccgtgcaggc gggcggcgtc cggctcgcgt agcgggagcc cgggctgatc
     1441 gggcggctgg acatcgagga cgccccgccg ctcctgccgc tcgacctgcc ccggccgccg
     1501 accgaacgcc cggaaggaga gctggacttc gactggccca tcgaggcggg ccacctcgtc
     1561 cacaccaccc ggccggagga gttcctcgcg gcgctcaggt cgttcggcct ggtgtgaccg
     1621 gtgagcctca cgtcccggtg ccggcggccg ccgccaccgc cttcgcccac cggtagtccg
     1681 ccttgccgct cggcgagcgc tggatccggt cggtgaggac cagggcgcgc gggatcttgt
     1741 atccggcgag ccgggtccgg cagtgggcct gcaccgcgtc gaggtccaac gccgctgctc
     1801 cctcgcgcag ttcgaggacg gctgcgaccc tgctgcccca gcgctcgtcg gggacgcccg
     1861 cgacgagcgc gtcgtacacg tccgggtggg acttgagcgc ctgctccacc tcctccggat
     1921 agaccttctc cccaccggtg ttgatgcact gcgagccccg gccgagcacg gtgacgatgc
     1981 cctccgcgtc gacggtcgcc atgtcaccca gcagcaccca ccgctcatcg cccttgcgga
     2041 agaaagtgtc ggcggtcttg gccgggtcgt tgtagtagcc gagcggcaca tggccgcgct
     2101 gggcgatgcg gcccacctca ccgggggcga ccggctcgta cgtcgccgga tcgaccacgg
     2161 cagtacgggc gttgacctga acccggaagc cgcgctcggg gcccgagtcg gcggtggccg
     2221 tgccgttgaa gccggactcg gaggagccga agttgttgag cagcatcacg gtcggcacga
     2281 gcgcctggaa ctccgcccgc accgaatccg acatgatcgc cccggagctg gagacggaga
     2341 acagcgacga gcagtccgtc ccgcgaagcg gcccgttgag ggcgtcgatc agcgggcgca
     2401 gcatcgcgtc ccccaccagc gacacgctgg tgaccttctc cctctcgatc gtccgcagca
     2461 cctcctcagg ggcgaacttg cggtgcacga cgacccgttg gccgaagttg aacccgatga
     2521 acgcggtcag cgtggaggtg ccgtgcatca gtgggggagt ggggaagaag gtgatgccgt
     2581 ctccgcccgc cgccacccgc tcagccagct cctgcgggct cttcaccggc tcaccggtcg
     2641 gcgcgccgcc gccgagaccg gagaagaaca ggtcctcctg acgccacatc acccccttcg
     2701 gcattccggt ggtgccgccg gtgtagatga tgaactggtc gtcggcagaa cgtggttcga
     2761 agccgcgcga gggggagccg gacgtctcgg cctcggtgaa ggggacggcc tccaggtccg
     2821 ggagcgcggc ggcggacccc acccggacca ggtggcgcag tgccggagcc tgtgcggacg
     2881 ccgccgcgac ccgctcgtcg aactcgccgt cgaagaccag cgccgccaga tccgcgtccc
     2941 ggtagaggta gaccagctcc tcttccacgt agcggtagtt gacgttcacc ggcaccaggc
     3001 gcgccttcag cgctcccagg accgtctgga ggtattcgat gccgttgtag aggtgcagcc
     3061 ccaggtgttc gcccgggcgg agccccgcgc cgatgaggtg gtgggctatc cggttggctg
     3121 cggcgtccag ttcggcgtag gtgaggcgcc gctcggcacc cgtaccggga tggtccacgt
     3181 acaggagcgc ctcgcggtcg gggaccacgt ccacgaccga ctcgaacagg tcggcaaggt
     3241 tgtactccac cgttcctcct gaccccgggt gactggcgac tcggccgtca ttagagcgcc
     3301 gggcggcaca agtgggaagg ggtggcgtcg aaagaatctg acgagctgtc agaaaactat
     3361 tgaactgcga ccccgcctac tgcaacctgt tccaggtctg cagacgggag ttcgtcatgg
     3421 gcggtacgga agacctgggt acggaacacg tcggtacgga acacgtcggt acggaacacc
     3481 tcaccgtgga gcgccggggc gccacgctgg tgctcacctt gaacagacca caggccagga
     3541 acgcgctgtc gctgccgatg ctcgtcggcc tgtacgacgg gtggctcgcg gccgacgccg
     3601 acgacgaggt gcgctcggtc gtcctgaccg gggcgggcgg tgcgttctgc tcgggcatgg
     3661 atctcaaggc gctcgcgggc ggcgggatgg agggtgagga gtaccgggag cggatgaccg
     3721 ccgacccgga cctccactgg aaggcgatgc tgcgccacca ccgcccgcgc aaaccggtga
     3781 tcgccgccgt ggaagggccc tgtgtcgccg gcggcaccga gatcctccag ggaacggaca
     3841 tccgcatcgc cggtgagggc gccaccttcg ggctcttcga ggtccggcgc ggcctgttcc
     3901 cgatcggcgg ctccaccgtc cggctgcccc gccagatccc ccgcacccac gccctggaaa
     3961 tgctcctcac cggccgcccg tacaccgccg acgaggctgc ctccatcggg ctcatcggcc
     4021 gcgtcgtgcc cgacggcacc gccctggagg aggccctcgc cgtcgccgag cggatcaacg
     4081 cctgcgggcc gctcgccgtc gaggcggtca aggcctcggt ctacgagggc gccgagctga
     4141 ccgagagcga ggcgctggcc gccgaactca agcgcggctg gcccgtgttc gccaccgagg
     4201 acgccaagga gggcgcccgt gccttcgccg agaagcgccc gcccgtctac cggcgcgcct
     4261 gagccgtggg ccccggagcc ccgagtcctg agcctttgga gagtgccatg accgacgtcc
     4321 tcagcgcccc gctggtggtc gaattcccct tcacccgatc cctcggcccc gtccagagcg
     4381 ccttcctcac cggactgcgc gaacgcaccg tcctgggcgt ccgcgccgac gacggcacgg
     4441 tcctcgtgcc gcccgtcgag tacgaccccg tcacggccgg cgagctccgc gaactcgtcg
     4501 aggtcgccgc caccggcacc gtcaccacct gggcgtggaa cccgtccccg cgccgcgacc
     4561 agccgctgga aaccccgttc gcctgggtcc tcgtccgcct cgacggcgcc gccaccgcgc
     4621 tcctgcacgc cctggacgcc cccgggcccg acgccgtgca caccggcatg cgggtccgga
     4681 tccgctgggc ggtcacccgc accggcgcca tcaccgacat cgcctgcttc gagccctacg
     4741 acggtgagcc cggccccgcc gaaccagcgc cccacgacgg ggagttcgcc gaccccgtga
     4801 ccggcatcgt cgccccggcc cgcctcgact acgtccactc cccgggccgc gcccagagcg
     4861 cctacctcaa ggcgctcgca ggccaccgca ccgtcggcga acgctgcccc gcctgccgca
     4921 aggtctacgt accgccgcgc ggagcctgcc ccacctgcgg catcgccacc gccgaacagg
     4981 tggaggtcgg cccgcgcggg accgtcacca ccttctgcat cgtcaacatc aaggcgaaga
     5041 acctggacat cgaagtccct tacgtctacg cccacatcgc cctcgacggc gccgacctcg
     5101 ccctccacgg ccgcatcgcc ggcatcccgt acgaccaggt ccgcatgggc ctgcgcgtcg
     5161 agcccgtctg ggccgagggc gccgcccacc ccgaccacta ccggcccacc ggggagccgg
     5221 acgccgacta cgacacgtac aaggagctgg tgtagatgcg agacgtggcg atcgtcgcct
     5281 tcgcccagac cgtgcaccgg cggcgtaccg acgaactctc cgaggtcgac ctgctgatgc
     5341 ccgtcctcca cgaggtgctc ggggcgacgg ggctgaaggc gaacgagatc gggttcacct
     5401 gctccggctc cgccgactac ctcgccggac gtgccttctc cttcaccatg gccctcgacg
     5461 gcgtcggcgc ccacccgccc atctccgagt cgcatgtcga gatggacggc gcctgggcgc
     5521 tgtacgaggc atgggtgaag atcatgaccg gtgaggcgga caccgcgctg gtctactcct
     5581 acggcaagtc ctcacccggc gaggtccgcg acgtcctcac ccgccagctc gacccgtact
     5641 acctcgcccc gctctggccg gactccgtct ccctcgccgc cctccaggcc caggccctca
     5701 tcgacgcggg tgacaccgac gaggcggccc tggcctccat cgccgcccgc agccgcaccg
     5761 acgccaccgc caacccgtac gcccagctca ccggcgacgt ccccgccggc gaccacctcg
     5821 tgcacccgct gcgcatcgga gactgcccgc ccatcggcga cggcgccgcc gccgtgatcc
     5881 tcgccgccgg ggacaccgcc cgcgccctgt gcgcacggcc cgcctggatc cgcggcatcg
     5941 accaccgcat cgaggcccac agcctcggcg tccgcgacct caccgactca ccctccaccc
     6001 ggctcgccgc ccagcacgcc ggagccttcg aacgcccttt ggacaccgcc gagttgcacg
     6061 ccccgttcac ctcgcaggag gtcgtcctcc gcaaggccct cgggctcggc gacgacaccc
     6121 ggatcaaccc gtccggaggc gcgctcgcag ccaacccgat catggcggcg ggcctcatcc
     6181 ggctcggcga ggccgccgcc cgcatccacc gcggcgagtc cgaccgggcc ctcgcccacg
     6241 ccacctccgg gccctgcctc cagcagaacc tggtcgccgt cctggaaggg gagagcgctc
     6301 atgtctaagg agcccgtggc cgtcgtcggc atcggccaga ccaaacacgt cgccgcccgg
     6361 cacgacgtct ccatcgccgg actggtccgc gaggcggcgg tccgtgccct ggaggacgcc
     6421 ggactgacct ggagcgacat cgacgccgtc gtcatcggca aggcccccga cttcttcgag
     6481 ggcgtcatga tgccggagct gtatctcgcc gacgcgctcg gagccgtcgg caagccgatg
     6541 ctgcgcgtcc acacggcggg ctcggtcggc ggatcgaccg cgctcgtcgc cgccaacctc
     6601 gtcgccgccc gtgtccaccg gaccgtcctg accctcgcct tcgagaaaca gtccgagtcc
     6661 aacgccatgt ggggcctctc cctgcccgtc ccgttccagc agccgctgct ggccggagcc
     6721 ggcggcttct tcgccccgca cgtccgcgcg tacatgcgcc gtacgggagc ccccgacacc
     6781 gtcggctccc tcgtcgcgta caaggaccgc cgcaacgccc tcaagaaccc ctacgcgcac
     6841 atccacgacg cggacatcac cctggagaag gtccaggcgt cgcccatgct ctgggacccg
     6901 atccgctact ccgagacctg tccctcgtcc gacggggcct gcgcgatggt cctcaccgac
     6961 cgcgagggcg cgagcagggc cccccacccg cccgcctggg tgcacggcgg cgccatgcgc
     7021 agcgaaccga cgctcttcgc cggcaaggac ttcgtctccc cgcaggccgg gaaggactgc
     7081 gccgccgacg tctaccggca ggcccggatc accgacccgc gccgggagat cgacgccgtc
     7141 gagatgtacg tcccgttctc ctggtacgag ccgatgtggc tggagaacct cggcttcgcc
     7201 ggtgagggcg agggctggaa gctcaccgag gcgggcgtca ccgaactcga cggcgacctg
     7261 ccggtcaacc cctcgggcgg tgtgctctcc accaacccca tcggcgcgtc cggcatgatc
     7321 cgcttcgccg aggcggccct ccaggtacgg ggacgggcgg gcgagcacca gatcgacggg
     7381 gccaccaggg cggtcggcca cgcctacggg ggcggggcgc agttcttcgc catgtggctc
     7441 gtcggctccc agcccccgcc ggggtgacac gtctgagagg gcgcgcgccc tctcagggca
     7501 gcgggcagct gacctgaagc acccgctcgg ccagccggcc cgtgaggcgg ccgtcggtga
     7561 cggcggcctc ctccagccag tccgccaccg tcaactgctc caccagcgac tccagctcgt
     7621 cgggctcgac ggcgcaccag gaggtgagga ccgccaggtc gacgccctcg ccctcggccc
     7681 ccagccggcc gtcggtcgtg gtcctcacgg ccagggccag ggcgaggagc cgggtggcgg
     7741 cgccggtctt cttcttgcgg agcttcttgt ccccgacgac ccgctgcgcc cagccactca
     7801 gcttggggcg cgtcttgcgg ccgaagtcga acgggccctg tccgtcgtcg tcgggcatca
     7861 gggacgggat ggtgatcggc gtggggctct cgggccggga ttcgagcagg tcgtcggcgg
     7921 tgccggggat ggacagccag ccggagtcca cgagccgccc gatcagctcc tcgggctcgg
     7981 tcaggggcag gcccctgacg tcctgcccca ccaggttgcc ggtgccggtg agcgccgagc
     8041 gcagggtcag catcaccgcc atcagacggg cctccggacc gggcagcggg gtgtgctcgg
     8101 cgacataggc gaggaccgtc cgcgcgtgct cccactgcgt gagaccgggc agcaggcggt
     8161 tggtgacctc tccctcgccg accgggctct ggccggtgcg ctgctggtgc tggaggaggg
     8221 cggcggcggc cgcctgctcg gcgcgttccg cgtccagccg cagctcggtc tccccggtga
     8281 cctccgccca cgtgcggaag gccttcgcct tacgggagtg gagttcggcg agctgctcca
     8341 ggtccggttc ggggcgctcc tgataggcgc ggaagaggtt gcccagctcg atcagctcgt
     8401 cgcgcagggc gatcgggtgc aggtcgtgcg gcacgaaccg ctgcgcgatc ttcccggtgc
     8461 ggcggttgcg ccggggcttc gtgcgaggga cgggcgcagc gcgggggacg ggcacggggg
     8521 cgggggacga ggcggcgtgg gagaagtgcg ggccgaccgg gacgggcggc gggcccgcgg
     8581 ctccacgcgc tcctgccgcg ggggccggtc cggcggcggc ccgggcgggg gcggccgggg
     8641 cggtggcgac gatcttcgcc gaggggtggg cggccgcaca gcgtgcgcag cactccagcg
     8701 cctgccacca gcgcccctgc cggtcgttga tgaccgcgag gacgaccggg cctccgcacc
     8761 gcagggccgg ggcgcggtcg cgggggccgt cggcccggac gtgcgtgtgg cattcctcgg
     8821 cccggcaggc gcaggatgcc tggggccggg gccccggggc ggctcgcaga tgcgtcgcga
     8881 ggtgagcgac ggctgccgtg cggccgacgg cggcggaggg cagaacctgg ggggcgcagg
     8941 ccggacggcc gcacgagacg cgtaccgccg cacctccccg gtcggccggg tccaggcgca
     9001 ccatccacgc gcgccccacc acccgctctt ccagcccgct cactgtgccc tccaccgtca
     9061 tcctgtcctc tctcccggcg catcgccgta cccgtgctgt ccggcgcatc gccgttcccg
     9121 tacccgtacc cgtacgcgcc gccgccgcta cggacggggc acggcggtga tccaacggta
     9181 tgcggcatgg agccccgtcg cgggcgaact tgctccgatt ccacgcggaa gagtctgcgc
     9241 cggggtcccg cccgcgcttc ccgccgacgg gcggagggcc gatgcggcgg ggcggtgttc
     9301 cgtcccgggc ccggctccgc aacgtgagcc gggccacgta acatggcagc atgtccttcc
     9361 tccgccgccg tagcgccgca acacccgcgg gcccggactt cgatgtcctg gccatggacc
     9421 cgggggactg gcccggcaac ctcggcgccg gtctgctccc cgcccccgac ggcagctgtc
     9481 agggcgtctt cctccggtac gacctgtacg gcggccgtgg cccggccatg atcatcggta
     9541 atctcccggc cggttcgccc gcccgcgaga ccgaggacgg ccaggttccc ttcgaggtcg
     9601 cgcagctgct gctggccctg gagaacgacg agccgatcga ggtcgtcagc agcgaggacg
     9661 tccccgtgat gcagggcgac aacctgctga tcgtccgccg ggtgaagctc tcggagagcc
     9721 ggatcgcctg cgtccagttc gaccgcagcg acggggtgct cgtgaccatc gccagctggg
     9781 accggcccat caccgacgac ctgtacaccc tcctcaagcc ccttccggca gagctgttcc
     9841 agcagggctg aaacgtcact gcataggcct cccgcatatg cgggaggcct atcgcgcatc
     9901 cggcccgggc tccggtgcat ccggcctcag cgcatccggc cccggcccgt cgcgaggttc
     9961 acgcgacggg ccggggccgg atgctgctgc ggtggcggga ctacgccctg ctgcccgcca
    10021 gctccgccat cagccgcgtc acctgcgccg ccgaggtgcc gagccccgta ggaccgctga
    10081 ggtgccaggg cgcgccgtgt ccgcgccgca ggtcctcctc gcggtaccgg cggcagcccc
    10141 ggtgccagat caggatgccc gcgagccagt gcttgagctc ctgcacatag cccgccagca
    10201 cctcccgcgc ctcggcgtcc aggccgaagt cgtcgtacag caccggaagt tcgacctccg
    10261 ccacatgcag gaactgccgc agtcgcgact tcatcaggtc gtgcacgatc gccacgcctg
    10321 tcggatagtc gaccccgaag aagttctgca cgaccaggac gccgttgtgc acctccccct
    10381 cgtactcgat ctccttctgg tacgagaaca ggtcgttcag caggcacgcg tagtccgccg
    10441 cggcgttctc cagcgactgc atcgggccgc tccggtagac cgcctccggc accgtcctgc
    10501 cgtgcccgag ccggcacagg ctcatcgtca ggttcgagcc gaaggtgtcc ctgcgcatct
    10561 cgacgtagtc gaccggatca gggatacggt tctgcgcctg gttggccagc tcccacagcc
    10621 agctctcggt catcgactcg atggcggtcc ggaaggtgcg ccgtgcgccc aggtccatgg
    10681 gctccgcggt cctgcgccac aggtcgccaa gcgaccgctc cagcgcgttc accggctccg
    10741 ggatggcctc accgtccagc ggcatgaaga gcgagaggcg ctcattggcc agccgcgccc
    10801 ccgccaggtc ccgggaccgc ccgtgcacca cggggaacca gtcgtcaccg tacgtacccc
    10861 aggccagcca tgccgaggag atgtccagct cctccggtga ggcgtccgga tggatgcccg
    10921 ccgcgcacag ggggaggtcg atcgcgacga tccgttcctc gtcccagatg tgcgagcccg
    10981 gaacccccgg ctgcgcctcc aggatgccca tccggcgcgc ccagtcgacg agccgtaccc
    11041 gggcaccctc cagatgcggg ctcagcgtcg tcccgaacgg cagctccagg tcggggatca
    11101 gggaggggcc cacgtgctgg aacggcagat ggctgtggct gcgggcccgc gccgtctccg
    11161 aacgcagcgt gaacttgatc gaggcggcgg acatgccgaa gcccgccacc gcctcgccgg
    11221 ccccgccccc gttcatgtac cggctggagc gcatgtgcca ctcatggcct ccggactgcc
    11281 agtcctgcag ccccttgacg tacgcgagga cggacgcggt ctgcgtcggg tcgaggccct
    11341 tctccgcgca gagcgggccc agttcggtga ggacggtgtt ctcgaactgc tggagccgtg
    11401 aggtcagcag gtcgttgacg gcctcggcgg cctcctgtgt ggagcagccg aggaacttct
    11461 ccaggacgag gaccccgttg ctgttctccc cctcctcctc gacctcgcgc tggtacgaga
    11521 agaggtcgtt gcgcaggtgc accccgtcgg agaaggcgtc gcgcagcacc cgcagcgggc
    11581 gggcgccggc cacctgggcg ggcacctccg cgccggccgc gtactccacc agcccggccg
    11641 accagggggc gccgccgacc ttgcggcgca tctcgatgta ctcgacgggg ttggcgatac
    11701 ggccctcgtt gatgttggag agctcccaca tcgactcgtt gagcaggttc tccgtcgact
    11761 ccgcgaaccg ggcccgccag gcgtccgaca tcgcggggac cgtacgcgtc cacagatcgg
    11821 cgaggcccgc ctcgacgggg ttctccggct cgggggtcgc ggccccgcgc tccatcggca
    11881 tgaaggcggg cagccggtcc agataccgct tggcgccctc acggtcgggg gtgcgcttga
    11941 acagctccag gaagtggtcg tcgaagaaga agacccagac ataccagtcg gtgaccaggg
    12001 acagtgcctc ggccgagcag tcggggtggg tgtaggcgca gagcagggcg tagtcgtgcg
    12061 cctccaggtc cttctcctcc cagatgccgg atccctccag catccccatg ccgcgcgccc
    12121 actgacgcgt gtgcgtccgt gccgcctcga catgagggtt gagccgcgcc ggatacggaa
    12181 catagaagtc cggcagtgag aagggctgtg ccatgtgcgt caggcctttc cgaagcctcc
    12241 gcgcggcgag cgcgcggacc agtagtggtg tccgcgccag ctctaccctt cggccaaccg
    12301 gggcacgcac cagggcgatt agtcggataa tcgcggtctg atctgtgccc gctcggtggc
    12361 ggtccgctct ctgtgggcgg agtcgactca gtaggcggag tcgacgttgt cgatcgagcc
    12421 gtacttgtcc gcggcgtagt tggcggcggc ggtgatgttg gcgaccgggt cggtgagctt
    12481 cttctcggtg ccgttgacgt ggtaggcgtc gaaggtcggc tggatcacct gcagcaggcc
    12541 cttggaggga atgccgttct gcgcgttgat gtcccagtcg ttgacggcgt tcgggttgcc
    12601 gctggactca cgcatgatgt tgcggtgcag cccctcgtag gagccgggga tgttcttctt
    12661 cttcatgatg tcgagcgact cgcgtatcca gccgtcgagg ttgttcttgt actgcttggg
    12721 tgcggcgacg gccttgcgct cggtggagcg gttggcggcc tgcttctcgg agcgcgcctt
    12781 ctcggcggac ttcttcgcct cggccttacg gtcggccaca gccttctccg cggcggcctt
    12841 gcgctccgcc acggccttct tcgctgcggc cgcgtcggcg gcggccttct tcgcggcggt
    12901 ctcctgggcg gccttcttgg ccgcggcttc cttcgccgtg gaggcaccgg cgaccttctc
    12961 cgcggcgatg gaggtcttgg ccgcggcggg ctgtgcgtcg ctctgcccgc cggtcgcggc
    13021 gatggccgtg acggaaccgg ccgcgacgag cacggcggtg gcgagcttgt gggagcgggt
    13081 gatgcggatg gtgcggggca tgcgtgagct cttccttttg gggacgggga ctgcggccgg
    13141 tggccgcgtg agcagagacc gagggggatc ggctgccgac cgccgggggc gctcgtcgca
    13201 ggctcggtct cggtgcttgc cgggatccat ggttaacggc cacctggaca ggaggcaata
    13261 accctattta ctactcctgg taggagaatg aggggaatac cggctttggg tgtttcgcgg
    13321 cgccgtgagg gaggtctcgc acccactacc gtggttcgta ggtgacgtgg gtctcgtggc
    13381 gcgcctcacc cggggagggc atcgggatgc cgcagagtca gtgccctgtc acgcagcgcg
    13441 gaacgcggaa aagcgcgctg cgggaccggt gtgtcggcac cggtcgcgca gcgcgctccc
    13501 tttacacagt ggtttcttcg tcgtgggtgt tcgggggaag gcggcccacc cgccttcccc
    13561 cgaacaccca cgcggccgcg tcggcggcgc tgatcacgcg tgcgcgatca gcgcgtcccg
    13621 accgccgccc gcaccgcccg tcgcgccatc gcgcagtcgt cgtgcagcct gcgcagcagc
    13681 agccgctgct cctcgcccga ggagagcgcc cccggccggt cctggcccgc gcccacggcg
    13741 ggcgcctcgc gcatggtgcg ctgcacggcc gtctcgtagt tacggatctc cctggtcagg
    13801 acgagcatca ggttcaccag gaacgcgtcc cgcgcggccg gccccctggc ctgcgccagc
    13861 tggctgatct ggcgtcgcgc caccggggcg tcaccgagca ccgcccacag ggtggccagg
    13921 tcgtagcccg gcagatacca gcccgcgtgc tcccagtcga ccagcaccgg cccggtcggg
    13981 gacagcagga tgttggagag cagcgcgtca ccgtggcaga actggcccat gccctggcgg
    14041 ccgcccgcct gggccagacc gtgcagaagc ttctgcagat cgcccaggtc acggtcggtg
    14101 aacaggccga gctcgtggta gcgggagatg cgcgaggcgt agtccagcgg cgcctcgaac
    14161 agcccgggcg gcggccgcca ggcgttcacc cgggcgatcg caccgagcgc cgcacggatg
    14221 tcggcccgcg gtggcgcctc cgccgggtgc cgggtcagcg cggccacccg gccgggcatc
    14281 cgctcgatca ccagcgtgca gttctccggg tccgccgcga tcagccgggg cacccgaacc
    14341 gggggccggt gccggacgaa cgcgcggtat gccgctattt cgtgctggaa ccgctcggtc
    14401 caggcggggg agtggtccag taaacacttc gccacggcgg tggcccgccc ggtggtgccc
    14461 acgatcagga ccgaacggcc gctgcgccgc agcacctgga ccgggttgaa ctcggggcag
    14521 atgcgctgca cggaggcgat ggccatccgc acctgcgcgc cctgcggccc ggagaggtcg
    14581 atgcgtccgc tgagaggtcc ggcacccggt cccgccgccc gccgggtccg gcccagaccc
    14641 tgcgccggcg caccggcgtg gggggcgaga tacggcccgc cgcccgtccc catgggacgg
    14701 agcggccggg gcggggcgga cacggaggac gatgctgtgt acatgggcga gacagatccc
    14761 ttcgtgcgcc gacaagttac gtgcgccaac ccggccgacg gccgttcggc accctgggga
    14821 gtacctaggg ctgccgggcg gggtggcgct ttcctacctg acaccgggtc acgggtggca
    14881 gaccatctgg cggaccctgg cgaaccctgg cgaatagtca cagcgcatct gacagggggt
    14941 tagtgtcaag tcagccgaga acctgggggc ttgacgtgac cggagaaccc aacacccgcc
    15001 tttctgacct gttcggcctg gccggctggt ccaagggcga actcgcgaga atggtgaacc
    15061 ggcaggcggc ggccatgggc cacccgcagc tggccaccga cacctcgcgg gtcaggcgct
    15121 ggatcgacat gggggagtcc ccccgtgatc ccgtgcccga agtgctggca gccctgttca
    15181 ccgagcggct cggccgtgtc gtgaccatcg aggacctcgg gttcggccgg cgcgggcgtg
    15241 tggggaaacg gcgtgacgcg gggaaggaac acgaccccga tcaactgccg tgggcgcccg
    15301 aacggacggc agcggtcctc accgaattca cgggaatgga cctcatgctc aaccgacgcg
    15361 gcatggtggg cgcgggcgcc gcgctcgccg ccggctcaac catcgccggc cccatgtacg
    15421 actggctgcg cagcagcccc gcttccgcgg ccgacgcgcc acgcgccaac gatccccagc
    15481 acgccgaccc cgccggtttc gaccggtacg aggccgcgcc cgtgggctcc gaggagatcg
    15541 aggcactgga gcactcggtc gaggtgttcc gcgcctggga cgcctcccgc ggcggcggcc
    15601 tccagcgcaa ggccgtcgtg ggtcagctca acgaggtggg cggcatgctc gcctaccgcc
    15661 accccgacca tctccagcgc cgcctgtggg gcgtcgccgc caacctcgcc gtactcgcgg
    15721 gctggatgtc ccacgacgtc ggcctcgaac ccaccgccca gaagtacttc gtcatcgccg
    15781 cccacgcggc cagggagggc ggcgaccggc cccgcgccgg tgaggcgctc tcccgcgccg
    15841 cacgccagat ggtccacctg ggccgccccg acgacgccct cgacctgatg aagctggcga
    15901 aatccggctc gggcgacgag accctgcccc gtacgcaggc gatgctgcgc accatcgagg
    15961 cctgggcaca ggcggcgatg ggcaagggcc aggccatgcg gcgcaccctc ggcgaggcgg
    16021 aggagctctt cgtctcggac aagggcgacg tgccggcgcc gagctggatg cagatgttcg
    16081 acgaggccga cctgcacggc atgcaggccc tggcgttccg caccctggcc gagcacgacc
    16141 cggccgccgc cgtcatcgcc cagcaccacg ccaagcaagc cctggagctg cgggtcaacg
    16201 gccgtcagcg gtccaagctc ttcgaccaca tctcactcgc ctcggcctgc ttcatcgccg
    16261 acgaccccga acagggcgac cggtacgccc ggctcgccct cgtgtcgatg ggggagacct
    16321 cctcgcaccg cacctgggac cggctgcgcg aaatgtaccg gctcaccggc cagttcgagg
    16381 gttacgccaa gatccaggac ctccgcaagc agatcgagct ctcgttgccg cagagcccgg
    16441 tcgcccacaa gtccaggggt acgcaggcct gatccccgta catgcacgcc ggcggaggcc
    16501 gtaaccgccg cgcgcgccca ccgtcatgaa ggcccggcag tcctgaacac cggtcccgcg
    16561 cttcctcacg ccccgatccg ggcgaccagc acacacgcgt cgtccaggcg ctcggccccg
    16621 ccgaactcct cgaccacgcc ccgcacgcat tcctgtgcgt cacgggcctg ggcgaaccgg
    16681 tgggcgaggg cgagcagttg ctccgggacc gcaccccggt cgccgcgccg cgtcaggccg
    16741 tccgtgtgca gcacgagcac gtcgccgggg agcaggcgta cctcgtcctg ctcgtaggcg
    16801 atccgcgacg cggcaccgag caacgccccc tcggggggcg gcagtcggcg tcccgttccg
    16861 tcgcggaaga gcaggggcgc ggggtgtccc gcctgcgccc aggagaggag gccggtcgtc
    16921 gggtcgaagc ggcagcacag cgcgctgccc agggcgggcc gcaccgatgt ttcgaggagg
    16981 tggtcgaggt gacccatcag ggcgcccggc tcgataccgg cgacggccat gccgcgcagc
    17041 gcgccgagca tcatggccag ggccgaggtg gcgggaaggc cgtgcccgga caggtcgccg
    17101 acgctcagca gggtccggcc gtccggcagc tccatcgcgt cgtaccagtc gccgccgatg
    17161 aggccgccgg ccgcggaggg gaggtggtgg gcggcgatgt cgagggcgcc gggccccccg
    17221 gccggaagga ggagcgaacc gcgccacggt ggcagcgcgg tctcctggac ctcggtggcc
    17281 gtccggtgcc gcgggcgctc gacgggctcg tcgcgccggg ccgagtcccg gttccggctg
    17341 acgctctcct cgccgcggcg cagctcgccg acgtctcgga gcacggccca catggaggcg
    17401 gtgcagccct cggagtcgag gaccggttcg cccgtcatgt gcagcgtgcg cacctggccg
    17461 tcggggcgca cgatccggaa ctccccgtcc atcggctgcc cgtccaccag acagcccgtc
    17521 accatcgagg tcagcttcgg ctggtcgtcg gggaacagga cggacggcag gtcgtccagg
    17581 gagaggggag gtgaaccggg aggccggccg aagatctcgt acaactcctc cgaccagctg
    17641 acctcgtcgg tgaggaggtt ccattcggcg ctgcccaccc ggttcgccga ggagcccgcc
    17701 gacgcgccgt ccgtgctcac gcggtcgtcc cggtccgccg agcgctgggc cggcgggccg
    17761 gccttgagct gacccagatg ctggtcgagg ttgtcgaggt actggacggc caggtcgcag
    17821 agggcgcgct gccagcgcgc ctgggggtcg tcctcgtcgg tcaccgccgt gttccgcccc
    17881 acggcttcca catctccgcg cagtcggcgc gcacggtgga tcaaggcgtc gacggcatcg
    17941 tgcgcggggg gctgtggtgc ggggcggtcc gcgaacagat gggacggcat ctcgtactcc
    18001 gatacaggcg cggtgcggcc gggtctcagg ggtcggccgc tctcgactgt cgcacaggct
    18061 gcggcggctc gtaagggatt cgaccacact cgatgcgttg ttgcttctgg catatgccac
    18121 cggctgcacg aggcgggcga gcctccgaac gagcgtacgg ctgaggggtg ttggcccttc
    18181 cccgtggcat aggcggccgc ggtgagcggg ctgacaggga atgcgcgtgc gcgcggtcga
    18241 gccgcccggc aggatgcctc gcatgccgga gcagccgagt gtcatccttc ccccgtggtc
    18301 cgtcctcgac gccttcggcg tgcgcggcat ccccgagccg ctgaccggcg gtcaggggcg
    18361 cagcgtgcgg gtcggcaggg ccgtcctgaa acccgcggag ggaaccgagg gcgagtcgga
    18421 gtgggccgcg tccgtcttcg agcggctgcc ccggggtgcc ggcttccgtg tgccgcggcc
    18481 gctgcgctcg gccggagggg acgccgtggt cgagggctgg acggccgccg agttcaccga
    18541 aggccgcccc ggccccagca ggcagtggcc cggggtcgtc gccaccggcc gcgccttcca
    18601 cgccgccctg cgcgagctgc cccgccccgc cttcctcgac cgccggaccc acccgtgggc
    18661 ggtggccgac cgggtcgcct ggggtgagga ggagaccgcc gtggtcccgg agctcgccga
    18721 accgttcgcc cgcctgctgt ccctgcggcg gcccgtggag gcggcggcgc agatcgtcca
    18781 cggcgacctc accggcaatg tgctcttcgc gcccggccag gaccccgtcg tcatcgactt
    18841 ctcgccctac tggcgcccac ccctctatgc ggaggccgtg gtcatcgggg acggcctgct
    18901 ctggtacgag cccgcccccg gcctcctcgt cggcggggga ggcgaccccc gctggcgcca
    18961 gatgctgatc cgggccctga tcttccggct cgtcgcgctg agcggactgg tcggcccgtc
    19021 ctggcgtgcc ggggagaagg aggcggctcg cctcctggcg gccacggagg ccgtggagcg
    19081 tggaacgtac gagggtcggg cgcagctctg agagccgccg ggggcggggc tctccggccc
    19141 gggaatgccg acgggtcggg ttgcgttacc ccatcagaac gaaaacgaat cccattcccg
    19201 ttacgagggt ggggtcgtcg agcaccacgg gaggcgccca tggcacgcaa cgaactcagg
    19261 cccgtcgtga ccctccggtc caccgccgga acggggagca gctacgtgac ccgcaagaac
    19321 cgccgcaaca cccccgaccg gctggaactg cgcaagttcg acgccgccgc cgggcagcac
    19381 gtcctcttcc gcgaaacccg ctgaccggat cgcgcggagg aaacccgcac gccaccgcac
    19441 ctgtcgccgc cgacgccgtc ggcgaggaag gaacgcatcc atgaagcccc gtatccaccc
    19501 cgtctcccgc cccgtggtct tccgcgaccg agcagcggac gtcgccttcc tgacccgctc
    19561 gaccgccgac tccggcgcgc gcgtgacctg ggaggacggc aacacctatc ccgtcatcga
    19621 cgtggagacc tcgtcggcga gccacccgtt ctacaccggg ggccgtcagg cgctcgacac
    19681 ggccggccgc gtggagcggt tccggcgtcg ttacggcacc gacgaggcgt cccggagctg
    19741 accgtcgccg gtcccgaccg gcgccggaac cggggattcc gtgccgtgga tcacatccgc
    19801 gggggcgggt tcccgggaac agtccgagat ggtttatcgt tcatctatac gtgggtgtga
    19861 gggggacagt gtccccgggc ctcaccacag cccatgggga aagttcgcac agccgaagcc
    19921 ccatggagac ccccgccgag aggcgaccgc ccttcacgcc cgcactcaag ccgccccggc
    19981 tggattcccc cgatccggcc ggggcttccc cgtgttccgg cccccgcgcc acccggtctc
    20041 gagaaccgtc gcacccgcca ccagcaccac cgcacccagc gcggccccgg gactccacca
    20101 ccgctccgtc agcgccgcga gcgccgcccc ggccaccacc gcccccagcc ggcccagcac
    20161 ccagccgtcc cccggctcca gtcgccgcgc cgccgcacgg ccggcgagcg aggtgagggt
    20221 cccggtgaaa tagttcgtcg gcgtcacccg gacccgcccc tggacgccca tcgccagcga
    20281 caccagggcc agcagcccga gccggtcacc gtacgacgcg accagcccga acccccacag
    20341 cgcggccgcc accccgagca ggaccgactc ggccagcagc gtcagaccca gggggagtcc
    20401 ggccatcagc gtcccggccg ccaccccgca cgcgtacgcc gccagggcgg tgaccacccg
    20461 cagcgccaca ccgtcctcgc ccgccccggc cgccgaggca cccagcagga ccagattccc
    20521 ggtcatcacc cccgcgaaga cctggcccac acagaggaag gcgaacgcgt ccgcggcccc
    20581 ggaagccgcg gagaggagca gcagcgccca cgcgccgcgc cgggaagagg cgtcggcccg
    20641 tgacgcgaga gaagagacgg aagaggggga cgggggcggg ggaggcgtgg gaggggagtg
    20701 cacgcgagca ttctcggtac gcccgcgctc cggtgtcgcg cgccgcgctg gatgcggcgc
    20761 gcccggtcac atggtctcgt ggaggtcctt ggcgtagtgc tcgatggccg gccggtactg
    20821 ctggacgtgc cggtcctcac tgttcgacgc caccacccgc agcagcagtt gcatcgcctc
    20881 gtggtgctcc tccgtgttga acagcgccat cgccaggaac gtctggagcg ccccgtcgtc
    20941 cgggaactcc tcgacgcccc ggcgcagcgt ctccacggcc tgcccgtacc gccccagcac
    21001 ccgataggta ctgccgaggc ccagcagcgc cccccgccgg tcctccgcgt cgagccccgt
    21061 tcccgccacg ctgcgctcgt agtacgccac cgcctcggtc tccaggccca ggacgtcatg
    21121 gacccacgcc gtccggtagg ccacctccgc gtcgtcgggg aactcggcgg tcagggcgag
    21181 cagtcgctcg cgtgcctccc cggcccggcc ctcttggcgt agccggtcgg tctcggccag
    21241 ctgatccttc ttctcacgtg cactcatgag atccatcgtc gcaggcagca ccgggtggcc
    21301 gggtgatttt cgggcccgga cgcccacccg ggtgttttcc ggcccggccg gggcatctgt
    21361 ccgccatgac tgcagagacg aacccccgta cgcgacacgg ggcatgggca cgcgtgctgc
    21421 tgagggtgac cgtcctgacc gtggtgctgc tgggactggt ggcgttctcc atcctcctgg
    21481 ccaaggtgac actcaccccc tcgccggcct ccgaggacat cgtcacgtcg aatctccagc
    21541 cgggccggtc gctgcgccag tacgccgagg actacacgtt cctcgccgcg tgcaagcagg
    21601 cgggcggcaa tgtgctgctg ggcgtgccct tcggactgct gctcccgttc ctcgtgccgc
    21661 gccgcctgcg gatgatcagc atgaccctgc tgaccgcggc cgccatggtc ctcgtcgaac
    21721 tggtccaggg cgccctggtc accggccgcg ccttcgacat cgacgacgtc atcctcaaca
    21781 cgtcgggtgc gctcctcggc tacctgctgc tgggccgtcg gatcagccac agctaccacg
    21841 tgcgcgcaca cactcctcgg gccgaggcgg tcgagccgga ggccgcggaa agggagacac
    21901 cctcccggac caaggccagg accgcgacga agaccggagc gaagacgaag accggtgcga
    21961 cgaagacagg cacgacgaag gccgggacgc ctgcccgggg cacgaccaag gcgaaggagc
    22021 cggtcgagac cggggcgcgg accggctcca cgcgcctgcc gaaggccagg ggttcgagcg
    22081 gccgtcgcac cgccggcgcc gcacagcccg gctccggccg cgccttgatg gaccgcctgc
    22141 gcaggcggtg accgtagcgg gggcaaggca gagccagagg cgggggcacg ggcaggggca
    22201 ggggctgccc gtgc
//
