LOCUS       NZ_KB891308            26612 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces sp. ScaeMP-e10 B061DRAFT_scaffold_2.3, whole genome
            shotgun sequence.
ACCESSION   NZ_KB891308
VERSION     NZ_KB891308.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. ScaeMP-e10
  ORGANISM  Streptomyces sp. ScaeMP-e10
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 992189)
  AUTHORS   Stepanauskas,R., Sieracki,M., Masland,D., Poulton,N., Swan,B.,
            Garcia,M.M., Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C.,
            Tapia,R., Chen,A., Kyrpides,N., Mavromatis,K., Markowitz,V.,
            Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G., Pagani,I.,
            Pati,A., Goodwin,L., Nordberg,H.P., Cantor,M.N., Hua,S.X. and
            Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Improved High-Quality Draft of Streptomyces sp. ScaeMP-e10
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 992189)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
REFERENCE   3  (bases 1 to 992189)
  AUTHORS   Stepanauskas,R., Sieracki,M., Masland,D., Poulton,N., Swan,B.,
            Garcia,M.M., Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C.,
            Tapia,R., Chen,A., Kyrpides,N., Mavromatis,K., Markowitz,V.,
            Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G., Pagani,I.,
            Pati,A., Goodwin,L., Nordberg,H.P., Cantor,M.N., Hua,S.X. and
            Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. ScaeMP-e10
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            Isolation Site                    :: Gulf of Mexico
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 03:00:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,185
            CDSs (total)                      :: 7,109
            Genes (coding)                    :: 6,996
            CDSs (with protein)               :: 6,996
            Genes (RNA)                       :: 76
            rRNAs                             :: 6, 1 (5S, 16S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 45 of 113
            Pseudo Genes (incomplete)         :: 82 of 113
            Pseudo Genes (internal stop)      :: 12 of 113
            Pseudo Genes (multiple problems)  :: 23 of 113
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:33:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 675497
            Orig. end                         :: 702109
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB891308.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405355
            Source DNA and Organism available from Cameron  Currie
            (currie@bact.wisc.edu)
            Source DNA available from Cameron  Currie (currie@bact.wisc.edu)
            Organism available from Cameron  Currie (currie@bact.wisc.edu)
            Contacts: Cameron  Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26612
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16612](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16612)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            267..1661
                     /locus_tag="B061_RS0119760"
     CDS             267..1661
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955422.1"
                     /locus_tag="B061_RS0119760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="STM4012 family radical SAM protein"
                     /protein_id="WP_018513248.1"
                     /sec_met_domain="PF04055 (E-value: 1.1e-15, bitscore: 54.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSTTTSSATATGIPAVRPYESYVYAYPHKTAYRPLPERPALRE
                     LWAAEPTSALSLYLHIPFCEVRCGFCNLFTRIGAPEELTTRYLDALDRQAVAVRDALGD
                     DEPVRFAAAAFGGGTPTFLTADELERLCDIAEKRMGADLLAVPLSVETSPSTATADRLA
                     VLADRGTTRVSIGVQSFVDAEARAAVRPQRRAEVETALGRIRDARIPVLNIDLIYGIDG
                     QTERTWLTSLDAALAWRPEELYLYPLYVRPLTGLHRLGAAATGPEAEALEAAAWDEQRL
                     RLYTVGRDHLLAHGYEQVSMRMFRRADAPQEGPEDYACQTDGMIGLGCGARSYTSALHY
                     SFDYAVDMREIRSIIDRFTATEDFSRAEVGRYVDAAEARRRHLLQSLLQAAGLPLDDYR
                     ARFGTDPRADFPAELARFADRGWLDAQAPEGLLRLSPLGLAHSDALGPALFSPGVRAAM
                     AAYERK"
     gene            1669..2598
                     /locus_tag="B061_RS0119765"
     CDS             1669..2598
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378201.1"
                     /locus_tag="B061_RS0119765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="STM4011 family radical SAM protein"
                     /protein_id="WP_018513249.1"
                     /transl_table=11
                     /translation="MDLTILYRGPLASCDYDCPYCPFAKRRDSRAQLTSDREALERFTA
                     WAAAQTGDRLSVLFTPWGEGLVRSWYRRALTELSQLPHIGRVAIQTNLSGRTTWLADAD
                     PERIALWCTYHPGQTPYERFLGRCRELSARGIRYSVGVVGFDEHLEEARRLRAALPAEV
                     YLWVNAAEGHTYTDEEAERWTELDPLFPYSRHPHRSAGLPCRTGESVISVDGDGTVRRC
                     HFVKAELGNLYDGSYRAALGPRACTLAVCDCHIGYVHLETLPLYDVFAGGVLERIPAGS
                     GAGPGPEPAPGGPVVPGPSRRTLPLLEP"
     gene            complement(2615..3442)
                     /locus_tag="B061_RS0119770"
     CDS             complement(2615..3442)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449852.1"
                     /locus_tag="B061_RS0119770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_018513250.1"
                     /transl_table=11
                     /translation="MADDSRTQQQNIIGSYAAIGDSFTEGVGDPGPDGTFVGWADRFAV
                     LLADRLPAPDAATNPDETRHGNFRYANLAVRGRLLDQIVEEQLPRAKELAPDLVTFCAG
                     GNDIIRPGTDPDDLAERFERAVADLTEAVGTVMVTTGFDTRGVPVLRHMRGKIATYNVH
                     LRAIADRYQCPVLDLWSLRSVQDRRAWDADRLHLSPEGHTRVALRAAQVLGHEVPADPD
                     QPWPPQAQRRPFDERRDNIQWAREYLVPWIGRRLRGESSGDHVEAKRPDLLPL"
     misc_feature    3462..3472
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.16"
                     /tool="antismash"
     misc_feature    complement(3510..3525)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.38"
                     /tool="antismash"
     gene            complement(3605..4582)
                     /locus_tag="B061_RS0119775"
     CDS             complement(3605..4582)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964841.1"
                     /locus_tag="B061_RS0119775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysM peptidoglycan-binding domain-containing M23
                     family metallopeptidase"
                     /protein_id="WP_018513251.1"
                     /transl_table=11
                     /translation="MPAKGKHRRPKSGPIHRGVLAAGTGGAVLALPLFGATGAHAAEKA
                     APAVQPAAAQSAQQAAPQAAPATAKKAAPKTYAVVSGDYLAKIATEHQLKGGWQKLYQD
                     NRSTVGENPGLIFPGMKLTLGAKATGTAVPSEAKKSAPAPKAAAPKKAAPKKAEPAPKA
                     DTLSADESDAAAESGATTQTGSSQSTGSGWTAPLDNANVTTQYRASGSSWSSGYHTGSD
                     FQAASGTPVKAIGPGTVVSAGWSGSYGNEVVIKHEDGMYSQYAHQSSLSVSAGQTVTGG
                     QQIGLSGSTGNSTGPHLHFEVRTGPSYGSDVDPVAYLRQHGVSL"
     regulatory      complement(4586..4746)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    4760..4774
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.09"
                     /tool="antismash"
     misc_feature    4871..4884
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.44"
                     /tool="antismash"
     misc_feature    5003..5016
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.22"
                     /tool="antismash"
     gene            5158..5970
                     /locus_tag="B061_RS0119780"
     CDS             5158..5970
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964842.1"
                     /locus_tag="B061_RS0119780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_018513252.1"
                     /transl_table=11
                     /translation="MTQQVPQVPPTETELTGVRNFRDVGGLPTEDGRRTAFGRLYRSGH
                     LAHATAEDALFLGGLGLHTVFDFRNSADHKLDGYDIELAGVRNVSIPLSDPADGAEFWR
                     LVRDGNIEQLRSILANGKGTERMITMYRSTIVDRTAEHSRVLHALAEDSVPALMHCAAG
                     KDRAGLSIAVSLLAVGVEREAIEADYLKSNDPHRRYKVKRTDMSETGMSPEVMELLNPL
                     FGAQASYLAAAFAAIDDTWGTTDRYLAEGLGVSPETRERLRERLLDQG"
     gene            complement(5975..6151)
                     /locus_tag="B061_RS39810"
     CDS             complement(5975..6151)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955417.1"
                     /locus_tag="B061_RS39810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6126 family protein"
                     /protein_id="WP_018513253.1"
                     /transl_table=11
                     /translation="MSDSEHYDPLTPRRPKAAKDTQERRMPRGLVIRLFAYLVVGHVIA
                     AFLYLLFVVAGAE"
     gene            complement(6195..6803)
                     /locus_tag="B061_RS0119790"
     CDS             complement(6195..6803)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955416.1"
                     /locus_tag="B061_RS0119790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_018513254.1"
                     /transl_table=11
                     /translation="MNPPDEGAADELPGVAPRLRDLRRGRGLTLETAAQRAGLSPAHLS
                     RLETGRRQPSLPMLLGLARIYGTTVSELLGEKPPEREAVIRGGAFEGAEADGWMYRRAG
                     GSGRAMQALRVRVPYGAQGDLVRVHPGEEWLYVLGGRLRVALGETAHDLDPGDSAHFDS
                     LTPHRIAALDRGGAELLFVHSLLQSPAAELCLGNALHAR"
     misc_feature    6834..6847
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.16"
                     /tool="antismash"
     misc_feature    complement(6835..6848)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.16"
                     /tool="antismash"
     gene            complement(6863..8260)
                     /locus_tag="B061_RS0119795"
     CDS             complement(6863..8260)
                     /NRPS_PKS="Domain: Aminotran_3 (45-367). E-value: 6.6e-89.
                     Score: 290.2. Matches aSDomain:
                     nrpspksdomains_B061_RS0119795_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492039.1"
                     /locus_tag="B061_RS0119795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_018513255.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.3e-89, bitscore:
                     296.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDGGPQGFDLKRLLAERGHERYDLHARHLNHQLPRMLHTIGFDK
                     VYERAEGAYFWDAEGNDYLDMLAGFGVMGIGRHHPVVRRALHDVLDAQLADLTRFDCQP
                     LPGLLAEKLLGHSPHLDRVFFGNSGTEAVETALKFARYATGKPRVLYCTHAFHGLTTGS
                     LSVNGESGFKDGFAPLLPDTPIALGDLDALRRELKRGDVAALVVEPIQGKGVHAAPPGF
                     LREAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVCVAKALSGGYVPVGA
                     TLGKDWIFRKVYSSIDRVLVHSASFGSNAQAMAAGLAVLTVMEDEETVANARQTGDLLR
                     ERLSALVDRYELLHEVRGRGLMIGIEFGRPTSLKLRSRWTMLQAARKGLFAQMVVVPLL
                     QKHRILTQVSGDHLEVIKLIPPLIIGEAEVDRFVAAFTEVMDDAHSGGGLMWDFGRTLV
                     KQAVANR"
     aSDomain        complement(7160..8125)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B061_RS0119795_Aminotran_3.1"
                     /evalue="6.60E-89"
                     /label="B061_RS0119795_Aminotran_3.1"
                     /locus_tag="B061_RS0119795"
                     /protein_end="367"
                     /protein_start="45"
                     /score="290.2"
                     /tool="antismash"
                     /translation="VYERAEGAYFWDAEGNDYLDMLAGFGVMGIGRHHPVVRRALHDVL
                     DAQLADLTRFDCQPLPGLLAEKLLGHSPHLDRVFFGNSGTEAVETALKFARYATGKPRV
                     LYCTHAFHGLTTGSLSVNGESGFKDGFAPLLPDTPIALGDLDALRRELKRGDVAALVVE
                     PIQGKGVHAAPPGFLREAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFRKVYSSIDRVLVHSASFGSNAQAMAAGLAVLTVMEDE
                     ETVANARQTGDLLRERLSALVDRYELLHEVRGRGLMIGIEF"
     gene            complement(8329..9348)
                     /gene="hpnH"
                     /locus_tag="B061_RS0119800"
     CDS             complement(8329..9348)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128938.1"
                     /locus_tag="B061_RS0119800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_018513256.1"
                     /sec_met_domain="PF04055 (E-value: 6.5e-17, bitscore: 58.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2e-09, bitscore: 32.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLFEQKLRKREKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKKKYVF
                     LCTNAMLMRKKLDKFTPSPYFAFAVHIDGLRQRHDESVAKEGVFDEAVAAMKEAKARGF
                     RVTTNSTFFNTDTPQTIVEVLNYLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFAGGNRARWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRQLIEETDWEKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETISSNR"
     gene            complement(9354..10001)
                     /locus_tag="B061_RS0119805"
     CDS             complement(9354..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513257.1"
                     /locus_tag="B061_RS0119805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018513257.1"
                     /transl_table=11
                     /translation="MAGAPGAAPPPAPLLVACALGIEQLALRSGRRPGGPVRVLRTGMG
                     PRAAEAAVAAALAPGGLADAAVIASGFCAGLAPGMHPGDLVVAEETRDADGASPCTGTG
                     LLVAALARAAPGATVHTGPLTGSDHVVRGPERAALRATGAVAVDMESAATLRTALCHGP
                     RPVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRAVLPAFYEWHRSLLLPRR"
     misc_feature    complement(9372..9374)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..12001)
                     /gene="shc"
                     /locus_tag="B061_RS0119810"
     CDS             complement(10001..12001)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964848.1"
                     /locus_tag="B061_RS0119810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_018513258.1"
                     /sec_met_domain="T2TS (E-value: 5.1e-147, bitscore: 486.3,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGAANLSAAPAGHPADTTTAADDVTAAARQAAERSVA
                     HLLGRQDEQGWWKGDLATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWN
                     TFYGGPSDLSATIEAYVALRLAGDRPDEPHMARASAWIREQGGIAAARVFTRIWLALFG
                     WWKWDDLPELPPELMFFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELH
                     TDPTEPNPPRKLAPAASWDGLFQRLDKGLHLYHKVAPRLLRRIAMNVAARWIVERQEND
                     GCWGGIQPPAVYSIIALHLLGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWD
                     TCLATIALVDGGLRPDHPALVKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVRHPDPARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNR
                     LPFCDFGEVIDPPSADVTGHVVEMLAVEGLGAHPRTRRGIEWLLAEQEACGAWFGRWGV
                     NYVYGTGSVVPALVAAGLPAAHPSIRRAVTWLESVQNDDGGWGEDLRSYTEEKWIGHGE
                     STASQTAWALLALLAAGRRDSRAVARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINY
                     HLYRQVFPLTALGRYVYGDPFADRTGAAQGA"
     gene            complement(12111..13214)
                     /locus_tag="B061_RS0119815"
     CDS             complement(12111..13214)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964849.1"
                     /locus_tag="B061_RS0119815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_051104658.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.8e-61, bitscore:
                     201.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTTGTRGESVTPANPASDTVDQTTDVTALLERGRALSAPVLRA
                     AVDRLAPPMDTVAAYHFGWIDAEGRPSDGDGGKAVRPALALLSAEAAGAPAEAGVPGAV
                     AVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALAYDVLLELGTVE
                     AGRAARRLTSATRKLIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACAVSIGAVLG
                     GADDRTADTLETYGYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRKKSLPVVAALA
                     AGGPASERLGELLAADAKSSDFDSFSEEEFAARAALIEEAGGREWTAQEARRQHTVAIE
                     ALHAVDMPHQVRAQLTALADFVVVRKR"
     gene            complement(13211..14596)
                     /gene="hpnE"
                     /locus_tag="B061_RS0119820"
     CDS             complement(13211..14596)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072793.1"
                     /locus_tag="B061_RS0119820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_026241698.1"
                     /sec_met_domain="DAO (E-value: 1.2e-07, bitscore: 27.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDETPRPVAVVVGGGLAGITAALRLADAGLEVTLLEGRPRLGGL
                     AFSFQRGDLTVDNGQHVYLRCCTGYRWFLDRIEAAHLAPLQDRLDVPVLDVGRAAGPRL
                     GRIRRTGLPVPLHLAGGLAAYPHLSLAEKANVGRAALALGRLDPADPALDRIDFATWLK
                     RHGQSERAIEALWDLVGVATLNATAPNASMALAAKVFKTGLLSEPGAADIGWATVPLGE
                     LHDTLARKALDTAGVRTELRAKVGSLTRTEDGRWSVESAGERIAADTVVLAVPQHETHD
                     LLPAGALDEPDLLLDIDNAPILNVHVIYDRKVLRRPFFAAIGSPVQWVFDRTHSSGLKG
                     PGQYLAVSQSAVQDEIDLPVAELRERYLPELERLLPAARGAGIRDFFVTRERTATFAPA
                     PGVGALRPGPRTRAPGLHLSGAWTATGWPATMEGAVRSGFQAADAALHDLGRPHGHPLE
                     EAA"
     gene            complement(14751..15692)
                     /gene="hpnD"
                     /locus_tag="B061_RS0119825"
     CDS             complement(14751..15692)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450952.1"
                     /locus_tag="B061_RS0119825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_043185532.1"
                     /sec_met_domain="phytoene_synt (E-value: 9.9e-58, bitscore:
                     191.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.5e-70,
                     bitscore: 233.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGQTTYMSPPVQAAYSYCEAVTGQQARNFAYGIRLLPYEKRQAM
                     SALYAFSRRVDDIGDGELDPATKRTRLESTRELLDRVRHGKVEEDDTDPVAVALSDAAR
                     RFPLPLEGLDELIDGVLMDVRGATHETWDDLKTYCRCVAGAIGRLSLGVFGTEPGAPGA
                     ERAPEYADTLGLALQLTNILRDVREDAANGRTYLPADDLAKFGCSAGFHRTTPPPGSDF
                     AGLIHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLRGRV
                     SLPGHEKAYVAVRGLSGLDARHISRLTSRGRA"
     gene            complement(15701..16612)
                     /gene="hpnC"
                     /locus_tag="B061_RS0119830"
     CDS             complement(15701..16612)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955408.1"
                     /locus_tag="B061_RS0119830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene synthase HpnC"
                     /protein_id="WP_018513262.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 6.2e-38,
                     bitscore: 126.3, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 2.4e-37, bitscore:
                     124.2, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTPEARTGDATLGKAADENFPVAPFFLPRAWRGDLMAVYGYAR
                     LVDDIGDGDLAPGGADARHLGLEPEQSNDRLAMLDALETDLHRVFATTGQEPHHPLLRA
                     LRPTVRRRALTPEPFLGLIEANRQDQKVRRYATYGELAAYCELSANPVGRLVLALTGTT
                     SPERVRLSDAVCTALQIVEHLQDVAEDLARDRIYLPAEDMDRFRVTEADLARPSAGASV
                     RALIAYESERAGELLRDGIPLVASVDGRLRLLLAGFVGGGRAALTAVSAAGFDVLPGPP
                     KPTKPSMLREAAVVLRRARRER"
     gene            complement(17030..17815)
                     /locus_tag="B061_RS0119835"
     CDS             complement(17030..17815)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964853.1"
                     /locus_tag="B061_RS0119835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_018513263.1"
                     /transl_table=11
                     /translation="MAEDNTQGRIPTVIADDVHIVYRVNGTGGGRGSATAALSRMMRRG
                     KGEPRGMRKVHAVRGVSFTAYRGEAIGLIGTNGSGKSTLLRAIAGLLPTESGRVYTDGQ
                     PSLLGVNAALMSDLTGERNVVLGGLAMGMSQAEIRERYDEIVDFSGINEKGDFITLPMR
                     TYSSGMAARLRFSIAAAKNHDVLMIDEALATGDHKFRVRSEARIRELRKEAGTVFLVSH
                     NNKSIRDTCDRALWLEKGELLMDGPTEEVLKAYERETGK"
     gene            complement(17808..18737)
                     /locus_tag="B061_RS0119840"
     CDS             complement(17808..18737)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="B061_RS0119840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_018513264.1"
                     /transl_table=11
                     /translation="MSDTTHDGGVALGAPPSADEGLGAAQLAAKYGLTVSGARPGLLAY
                     LRQLWGRRHFILAFSRAKLTAQYSQAKLGQLWQVVTPLLNAAVYYLIFGLILGTREGIP
                     HDVFVPFLVTGVFVFTFTQSSVMAGVRSISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSMIVLVAVAIIFGSYPSLSWLLVIPALILQFFFNTGLALVMARLGSKTPDLAQLMPFI
                     TRTWMYASGVMFSIPVMLKDKPAWIADVLQYNPAAIYMDLVRFALIDGYGSENLPDHVW
                     AAGLAWAVLLGVVGFVYFWKAEERYGRG"
     gene            complement(18839..19711)
                     /locus_tag="B061_RS0119845"
     CDS             complement(18839..19711)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513265.1"
                     /locus_tag="B061_RS0119845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_018513265.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.9e-09,
                     bitscore: 33.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGAVIITMGDRPDELRALLDSVIAQEGDRIEVVVVGNGAPVGS
                     VPAGVRTVELPENLGIPGGRNVGIEAFGPSGADVDALLFLDDDGLLPGRDTAELCRQAF
                     AADPRLGIITFRITDPDTGATQRRHVPRLRAADPTRSSRVTTFLGGANAVRTRVLAEAG
                     PLPEQFFYAHEETDLAWRALDAGWMIDYRADLVLHHPTTAPSRHAVHHRMVARNRVWLA
                     RRNLPAPLVPLYLGVWLLLTLVRRPSPPALKAWFGGFREGWATPCGPRRPMKWRTVWRL
                     TRLGRPPVI"
     misc_feature    complement(19676..19690)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            complement(19720..20499)
                     /locus_tag="B061_RS0119850"
     CDS             complement(19720..20499)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="B061_RS0119850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_026241699.1"
                     /transl_table=11
                     /translation="MPRPSVAELRPVVHPPGVKDRRSGEHWAGRMYMREVSLRVDRYLV
                     NTKVTPNQVTYVMTLAGVLAAPALLVPGIPGALLGVLMVQLYLLFDCVDGELARWKKQY
                     SLSGVYLDRVAAYLCDAAVLVGLGLRAADIWGEGRIDWLWAFLGTLAALGAIMIKAETD
                     LVGVARHQGGLPPVKEAASEPRSSGMALARRAAGALKFHRLILGIEASLLILLVAILDT
                     IGGDLFYTRLATAVLAGIALLQTLLHLVSVLASSRLK"
     gene            complement(20477..21538)
                     /locus_tag="B061_RS0119855"
     CDS             complement(20477..21538)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="B061_RS0119855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_018513267.1"
                     /sec_met_domain="Fe-ADH (E-value: 3.7e-19, bitscore: 64.4,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.6e-10, bitscore:
                     36.2, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRRGAMDDLAGLLADQRISSSGKLAIAISD
                     GSGRALRERLAPVLPGADWYAVADGTIDSAVKLADGIKGTRYDAVVGLGGGKIIDVAKY
                     AAARVGLPMVAVATNLSHDGLCSPVATLDNDNGRGSYGVPTPIAVVIDLDVIREAPARY
                     VRSGIGDAVSNISCVADWELAHEVNDEEIDGLAAAMARQAGEAVLRHPGGVGDDAFLKV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLYPQRAASHGEQVGLGACFAMHLRG
                     ARQEALLMASTLRRHGLPVLPEEIGFTVDEFVRAVDYAPQTRPGRFTVLEHLSLSTDQI
                     RDAYADYASTISS"
     gene            complement(21526..22263)
                     /locus_tag="B061_RS0119860"
     CDS             complement(21526..22263)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955403.1"
                     /locus_tag="B061_RS0119860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_018513268.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.2e-12, bitscore:
                     44.0, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGDKTVLDLTLANFAEV
                     GLTEVAIVVGYRKEAVYARKAELEATYGLTLTLIDNDKAEEWNNAYSLWCARDVLKRGV
                     ILANGDTVHPVSVEKTLLDARGKGQKIILALDTEKSLADEEMKVITEEGKGVQRITKLM
                     DPATATGEYIGVTLIEAEAAEELADALKTTFERDPDLYYEDGYQELVNRGFTVDVAPIG
                     TVTWVEIDNHDDLEKGREIACQY"
     gene            complement(22260..24014)
                     /locus_tag="B061_RS0119865"
     CDS             complement(22260..24014)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955402.1"
                     /locus_tag="B061_RS0119865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_018513269.1"
                     /transl_table=11
                     /translation="MVSAADAGDAAALLADVPADHRVALVDPRFLGHLHALRLGLTDPR
                     FPAATVTGALTAQPQARPALVRALERATAAVGAGAPAVDPGAGPAPGDPTVPGRIAVEL
                     EAEGIAVQRPALGSLVAAVPTDRDQEAAAVAGLVAVDDEAVRLRNAVKSRDGFFTTFCI
                     SPYSRYIARWCARRGLTPNQVTTASLITALIAAGSAATGTRGGYIAAGILLLVSFVLDC
                     TDGQLARYSLQYSTMGAWLDATFDRAKEYAYYAGLAIGAARGGDDVWVLALGAMVLQAC
                     RHIVDFSFNEANHDSVANTSPTAALSDALDNVGWTVWVRRIIVLPIGERWAMIAVLTAL
                     TTPRTVFYALLIGCALAATYTLVGRLLRSVTRKARRTERAARALADLADSGPLAQAVAS
                     LVHGPKRALTAPAAALIGTLVMVGAALFLPYGSWLTVVAAAVYVVLSGFAVARPLRRAL
                     DWLVPPFFRVAEYVTILVLAARSDVPHAVPAAFGLVSAVAYHHYDTVYRIRGGTGAPPQ
                     WLVRTIGGHEGRTALVAVLAASLTHTSGFTTALTALAVAVALVVLVESIRFWVSSSAPA
                     VHDEGELA"
     misc_feature    24251..24266
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.68"
                     /tool="antismash"
     misc_feature    complement(24254..24269)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    24255..24269
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            24332..25348
                     /gene="galE"
                     /locus_tag="B061_RS0119870"
     CDS             24332..25348
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (66-205). E-value:
                     1.6e-08. Score: 25.9. Matches aSDomain:
                     nrpspksdomains_B061_RS0119870_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964864.1"
                     /locus_tag="B061_RS0119870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_026241700.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.5e-16, bitscore:
                     54.4, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 9.2e-13,
                     bitscore: 43.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMVAAGKRVVVLDDRSSGIVDRLPEAV
                     TLVEGSAGDRELLGRVLGEHAVSGVVHLAAKKQVGESVEKPLLYYRENIAGLTVLLEAV
                     VAAGVRRFLFSSSAAVYGVPDVELITEETPCLPINPYGETKLAGEWLVRATGKAHGIST
                     ACLRYFNVAGAAGPELADTGVFNIVPMVFDRLTRGEAPRIFGDDYPTPDGTCIRDYIHV
                     ADLADAHLAVARKLGVREGGDLTLNVGRGEGVSVRELIDVIREVSGHPVEPLVEPRRPG
                     DAAKAVASDARMVRELGWTARRDVRSMVESAWEGWCLRHPEARTGARGGREALDQRP"
     CDS_motif       24335..24421
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B061_RS0119870_0001"
                     /evalue="5.10E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="B061_RS0119870"
                     /protein_end="30"
                     /protein_start="1"
                     /score="28.8"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMVAAGKRVVVL"
     CDS_motif       24503..24553
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B061_RS0119870_0002"
                     /evalue="1.90E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="B061_RS0119870"
                     /protein_end="74"
                     /protein_start="57"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="LGRVLGEHAVSGVVHLA"
     aSDomain        24530..24946
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B061_RS0119870_NAD_binding_4.1"
                     /evalue="1.60E-08"
                     /label="B061_RS0119870_NAD_binding_4.1"
                     /locus_tag="B061_RS0119870"
                     /protein_end="205"
                     /protein_start="66"
                     /score="25.9"
                     /tool="antismash"
                     /translation="VSGVVHLAAKKQVGESVEKPLLYYRENIAGLTVLLEAVVAAGVRR
                     FLFSSSAAVYGVPDVELITEETPCLPINPYGETKLAGEWLVRATGKAHGISTACLRYFN
                     VAGAAGPELADTGVFNIVPMVFDRLTRGEAPRIFG"
     misc_feature    complement(25401..25415)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            25510..26451
                     /locus_tag="B061_RS0119875"
     CDS             25510..26451
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049646.1"
                     /locus_tag="B061_RS0119875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_018513271.1"
                     /transl_table=11
                     /translation="MGAGHDHGHTHGGPPPTGTAAAAYRGRLRVALGITLSVMVMEIVG
                     GVLSDSLALIADAAHMATDALGLGMALLAIHFANRPAGPNRTFGFARAEILAALANCLL
                     LLGVGGFLIFEAVDRFITPAETKGGLAIAFATVGLVANVVSLSLLMRGQKESLNVRGAY
                     LEVMADTLGSIAVIVSAGIIMATGWQAADPIASLVIGLMIVPRTVKLLRETLNVLLEAA
                     PKGVDMAEVRAHITALPGVLGVHDLHAWTITSGMPVLSAHVVVRQEMLDSIGHEKVLHE
                     LQGCLGDHFDVEHCTFQLEPSGHAEHEAHLCH"
     misc_feature    complement(26501..26516)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.04"
                     /tool="antismash"
ORIGIN
        1 catcagccga actggttcca caccccgggc gcaacccgcg aaaccggtga ctcccgggcc
       61 acgcacgcgg ccgccctgga gtacgtcgac cggcacatcg gccggctctt cgccgccgcg
      121 agcagccgcc gccggtgttt cgccatcgtc tgctccgacc acggcaccac ctacggcgac
      181 gacggctaca ccggccaccg gctcggccac gaggccgtct ggaccgtgcc ctacgcgcac
      241 ttcttcctcg aaccgggggc ctcctgatga ccaccagcac caccacgagc agcgctacgg
      301 cgacaggcat tcccgccgtc aggccgtacg agagttacgt ctacgcctat ccgcacaaga
      361 cggcctaccg ccccctgccg gagcggcccg cgctgcgtga gctgtgggcg gcggagccca
      421 cgagcgccct ctccctctac ctccacatac cgttctgcga ggtccgctgc ggcttctgca
      481 acctcttcac ccggatcggc gcgcccgagg agctgacgac ccgctatctc gacgccctgg
      541 accggcaggc cgtggccgta cgggacgcac tcggcgacga cgagccggtg cggttcgcgg
      601 cggcggcctt cggcggcggg acgccgacct tcctcacggc ggacgagctg gagcggctct
      661 gcgacatagc ggagaagcgg atgggcgccg acctgctcgc ggtgccgctg tcggtggaga
      721 cctccccgtc caccgcgacc gccgaccgcc tcgccgtact ggccgaccgg gggacgaccc
      781 gggtcagcat cggcgtacag agcttcgtgg acgcggaggc gcgggccgcc gtccgtccac
      841 agcgccgggc cgaggtggaa accgcgctcg gccggatccg ggacgcccgg ataccggtgc
      901 tcaacatcga cctgatctac ggcatcgacg gccagaccga gcgcacctgg ctcacctccc
      961 tggacgccgc gctggcctgg cggccggagg agctgtacct ctacccgctg tacgtccgcc
     1021 cgctgaccgg cctgcaccgt ctgggcgccg ccgcgaccgg ccccgaggcg gaggccctgg
     1081 aggcggccgc ctgggacgag cagcggctgc ggctgtacac ggtggggcgg gaccatctgc
     1141 tggcgcacgg ctacgagcag gtgtcgatgc ggatgttccg gcgcgccgac gcaccccaag
     1201 aaggtcccga ggactacgcc tgccagaccg acggcatgat cggcctgggc tgcggggccc
     1261 gttcctacac ctccgccctc cactactcct tcgactacgc ggtggacatg cgggagatcc
     1321 gctccatcat cgaccggttc accgccaccg aggacttctc ccgggccgag gtcggcaggt
     1381 acgtcgacgc ggccgaggcc cgcaggcgcc acctcctcca gtcgctgctc caggcggcgg
     1441 gcctgcccct ggacgactac cgcgcccgct tcggcacgga cccccgtgcg gacttccccg
     1501 ccgagctggc gcggttcgcg gaccggggct ggctggacgc gcaggcgccc gagggccttc
     1561 tgcggctctc ccccctgggc ctggcgcact cggacgcgct gggtccggcg ctgttctccc
     1621 ccggggtgcg ggccgcgatg gccgcgtacg agcggaagtg agcgggccat ggacctgacg
     1681 atcctctacc ggggcccgct ggcctcgtgc gactacgact gtccgtactg cccgttcgcc
     1741 aaacggcggg acagccgggc gcagttgacc tccgaccggg aggcgctgga gcggttcacc
     1801 gcgtgggcgg cggcccagac aggcgaccgg ctctccgttc tgttcacccc gtggggcgag
     1861 ggcctggtgc gctcctggta ccggcgtgcg ctgaccgagc tgtcccagct gccgcacatc
     1921 ggacgcgtcg ccatccagac gaacctcagc ggccgcacca cgtggctggc ggacgccgat
     1981 ccggagcgga tcgcgctctg gtgcacgtac cacccggggc agaccccgta cgagcggttc
     2041 ctcggccgct gccgggagct gtccgcgcgc ggcatccgct acagcgtggg cgtggtgggg
     2101 ttcgacgagc atctggagga ggcccggcga ctgcgggctg cactgcccgc cgaggtctac
     2161 ctctgggtga acgccgccga ggggcacacg tacaccgacg aggaggcgga gcggtggacg
     2221 gagctggacc cgctcttccc ctacagccgg catccgcacc gctcggccgg gctgccctgc
     2281 cggacgggcg agtcggtgat ctcggtggac ggcgatggca cggtgcggcg ctgccacttc
     2341 gtcaaggcgg agctgggcaa cctctacgac ggcagctacc gcgcggcgct cggcccccgg
     2401 gcctgcacgc tggccgtgtg cgactgccac atcggctatg tgcacctgga gacgctgccg
     2461 ctgtacgacg tgttcgcggg cggcgtcctg gagcggatac ccgccgggtc cggcgcgggc
     2521 ccggggccgg aacccgcgcc gggcggaccc gtggtccccg gcccgtcccg gcgtacgctc
     2581 cccctgctcg aaccctgatc cctacagctg atccctacag cggcagcagg tccggccgct
     2641 tcgcctcgac gtggtcgccg gacgactcgc cgcgcagccg ccggccgatc cacggcacga
     2701 ggtactcccg cgcccactgg atgttgtcgc gccgctcgtc gaagggacgg cgctgggcct
     2761 gcggcggcca gggctggtcc gggtcggccg gcacctcatg gccgaggacc tgggcggcgc
     2821 gcagcgcgac gcgggtgtgg ccctcgggcg acaggtggag ccggtcggcg tcccacgcgc
     2881 gccggtcctg gaccgagcgc agcgaccaca ggtcgagcac agggcactgg tagcggtcgg
     2941 cgatggccct caggtgcacg ttgtacgtgg cgatcttgcc gcgcatgtgg cgcagcaccg
     3001 gaacgccccg ggtgtcgaac ccggtggtga ccatgacggt gccgaccgcc tcggtcaggt
     3061 ccgcgacagc ccgctcgaag cgctcggcca gatcgtcggg gtcggtgccg ggccggatga
     3121 tgtcgttgcc gcccgcgcag aaggtgacca ggtcgggggc cagttccttg gcgcggggga
     3181 gctgctcctc gacgatctgg tcgaggaggc gtccgcgtac ggcgagattg gcgtagcgga
     3241 aattgccgtg ccgggtctcg tccgggttcg tcgccgcgtc gggggcgggg agccggtcgg
     3301 cgagcagaac cgcgaaccgg tccgcccagc cgacaaaggt gccgtcgggg ccgggatcgc
     3361 cgacgccctc cgtgaaactg tccccgatcg ccgcgtacga cccgatgatg ttctgctgct
     3421 gggttctcga atcgtctgcc acaagcacat atcctgcacc gttcaatgtg acctacgcga
     3481 ccgtaatacg gggttgacgg gtggtgacat agaccacccg gtcagatttc ggtaaagccg
     3541 gaataagtgg aggggcggtg cgccgccgcg caccgcccct cgatcacttc ttctcgccct
     3601 ggggtcagag ggagacgccg tgctggcgca ggtaggcgac cgggtcgacg tccgagccgt
     3661 agctcgggcc ggtgcggacc tcgaagtgga ggtgcgggcc ggtggagttt ccggtggagc
     3721 cggagaggcc gatctgctgg ccgccggtga cggtctggcc ggcggagacg ctcagcgagg
     3781 actggtgggc gtactgggag tacatgccgt cctcgtgctt gatgacgacc tcgttgccgt
     3841 acgaaccgct ccagccggcc gagaccacgg tgcccgggcc gatggccttg acgggggtgc
     3901 cggaggcggc ctggaagtcg gagccggtgt ggtagccgct ggaccagctg gagccggaag
     3961 cgcggtactg ggtggtgacg ttggcgttgt cgagcggcgc ggtccagccg gagccggtgg
     4021 actgcgagga gccggtctgc gtggtggcgc ccgactcggc ggcggcgtcg gactcgtcgg
     4081 ccgagagggt gtcggccttc ggggccggct cggccttctt cggggcggcc ttcttcggcg
     4141 cggcggcctt gggggccggg gcggacttct tggcctccga aggcacggcg gtgccggtgg
     4201 ccttggcgcc gagggtcagc ttcatgcccg ggaagatcag gccggggttc tcgccgacgg
     4261 tcgagcggtt gtcctggtac agcttctgcc agccgccctt gagctggtgc tcggtcgcga
     4321 tcttcgcgag gtagtcgccg gagacgacgg cgtacgtctt cggggcggcc ttcttcgccg
     4381 tggcgggcgc ggcctgcggt gcggcctgct gggcgctctg ggcggcggcg ggctggacgg
     4441 cgggggcggc cttctccgcg gcgtgggcgc cggtcgcgcc gaacagcggg agggcgagta
     4501 cggcgccgcc ggtgcccgcg gcgaggacgc cgcggtggat cgggccggac ttgggacggc
     4561 ggtgcttacc ctttgcgggc atggggaagt tcctctccgg cgcctgcgag gtgagctgtc
     4621 gggttcgggc tggagatgcc cggccgccgg atggcgactt cacccctagc cggtccggat
     4681 cgctccgggc cggcggctta cctggttccc ccgctcctgc cacacgtgag tgggtgggtg
     4741 cgaattccgg gcggcggcag gattaggcgg tccgtccgga ttgacggtga ccgtaaacga
     4801 gtgaggacga cgggaacaag ccgtcggttg cgccccggaa tcatcgattc aatttcgctc
     4861 cggatttccc gtcaccctcc gtggattacg gatcttggct ttccgtgcgg atcccgggaa
     4921 atagccaggg cgccgccgcc acggtccgtc acggatatga tcccgctcac ctacggaatc
     4981 ccatctcccc cattagcagg gcatgttcta cgaaatgcac caatacggac atgccgccga
     5041 cgcgccccct gacgccccgt cagccttccg atgattgccc cgtgaaccga tgtcgtatcg
     5101 tcacaggagc gccctcgccg gagagccgcg ccgacgccga agattccagg agccaccgtg
     5161 acgcagcagg tgccacaggt cccgccgacc gagaccgaac tgaccggagt ccgcaacttc
     5221 cgtgacgtgg gcgggcttcc caccgaggac gggcggcgca ccgccttcgg ccggctctac
     5281 cgcagcggcc acctggcgca cgccaccgcc gaggacgcgc tcttcctcgg cggactcggg
     5341 ctgcacaccg tcttcgactt ccgcaattcc gccgaccaca agctcgacgg gtacgacatc
     5401 gagctggccg gtgtccgcaa tgtcagcatt ccgctctccg acccggccga cggagcagag
     5461 ttctggcggc tggtccgcga cgggaacatc gagcagctgc gctcgatcct ggcgaacggc
     5521 aagggcaccg agcgcatgat caccatgtac cgctcgacca tcgtggaccg caccgccgag
     5581 cacagccgcg tcctgcacgc gctggcggag gacagcgtgc cggccctgat gcactgcgcg
     5641 gcgggcaagg accgggccgg cctgtcgatc gcggtctcgc tgctcgcggt cggcgtcgag
     5701 cgcgaggcga tcgaggcgga ctacctcaag tccaacgacc cccaccgccg gtacaaggtg
     5761 aagcgcacgg acatgtcgga gaccgggatg tcccccgagg tgatggagct cctcaacccg
     5821 ctcttcgggg cgcaggcctc ctacctcgcg gcggcgttcg cggccatcga cgacacctgg
     5881 ggcacgaccg accgctacct ggcggagggg ctgggcgtct cccccgagac ccgggagcgg
     5941 ctgcgcgagc gcctcctcga ccagggctga gcgcctactc ggcgcccgcc accacgaaga
     6001 gcaggtagag gaaggccgcg atcacgtggc cgaccaccag gtaggcgaag agccggatca
     6061 ccagaccgcg cggcatccgg cgctcctgcg tgtccttcgc ggccttgggc cgccgtggcg
     6121 tcagcgggtc gtagtgctcg gaatcggaca tgacggtcct ctctgccggc ctcgcggccg
     6181 ggggaacgaa ggggtcagcg cgcgtggagc gcgttgccga ggcagagctc ggccgcgggg
     6241 ctctgcagca gggagtggac gaagagcagc tccgccccgc cccggtccag ggccgcgatc
     6301 cggtgcgggg tgagcgagtc gaagtgggcg ctgtcgcccg ggtccagatc gtgcgcggtc
     6361 tcccccagcg cgacccgcag ccgcccgccg aggacgtaca gccactcctc accggggtgc
     6421 acccgcacca gatcgccctg ggcgccgtac gggacccgga cccgcaacgc ctgcatggcg
     6481 cggccggagc cgccggccct gcggtacatc cagccgtccg cctcggcgcc ctcgaaggcg
     6541 ccgccgcgga tgaccgcctc ccgctcgggc ggcttctcgc cgaggagctc ggagaccgtc
     6601 gtaccgtaga tacgggcgag gccgagcagc atgggcagcg agggctgcct gcggccggtc
     6661 tccagccggg agaggtgggc cggggagagc ccggcccgct gggcggcggt ctccagggtg
     6721 agaccgcggc cgcggcgcag gtcgcgcagt cggggggcga cgccggggag ctcgtcggcc
     6781 gccccttcgt ccggagggtt catgggtcca ttgggccagg aactttcctc cggggcaaat
     6841 attttgcccc ggaggcaaaa gctcagcggt tggccacggc ctgcttgacc agggtccggc
     6901 cgaagtccca catcaggccg ccgccgctgt gcgcgtcgtc catgacctcc gtgaacgccg
     6961 ccacgaagcg gtccacctcc gcctccccga tgatcagcgg cgggatcagc ttgatcactt
     7021 ccaggtggtc gccggagacc tgggtgagga tgcggtgctt ctggagcagc ggcaccacga
     7081 ccatctgggc gaagagcccc ttgcgggccg cctggagcat ggtccaccgg ctgcggagct
     7141 tcagcgaggt ggggcggccg aactcgatgc cgatcatcag cccgcgcccg cgcacctcgt
     7201 gcagcagctc gtagcggtcc accagggcgg agaggcgctc ccgcagcaga tcaccggttt
     7261 gccgggcgtt cgcgacggtc tcctcgtcct ccatcaccgt gagcaccgcg agccccgcag
     7321 ccatggcctg ggcgttggag ccgaagctgg cggagtggac gaggacccgg tcaatcgagg
     7381 agtagacctt gcggaagatc cagtccttgc cgagcgtcgc gccgaccggc acatagccgc
     7441 cggagagcgc cttggcgacg cagaccaggt cgggctccac gccgtcctcg tgctggtacg
     7501 cgtagaagtc gccggtcctg ccgagcccgg tctgcacctc gtcggcgatc agcagcgcct
     7561 tgtgccggtg cagcagctcc tgcgcctcgc ggaggaagcc gggcggtgcg gcgtgcacgc
     7621 ccttgccctg gatcggctcc acgaccaggg ccgccacatc gccgcgcttc agctcccggc
     7681 gcagcgcgtc caggtcgccg agcgcgatcg gggtgtcggg cagcagcggg gcgaagccgt
     7741 ccttgaagcc gctctcgccg ttgaccgaga gggagccggt ggtcagcccg tggaaggcgt
     7801 gggtgcagta gaggacgcgg ggcttcccgg tggcgtaccg ggcgaacttc agtgccgtct
     7861 cgactgcctc cgtaccgctg ttcccgaaga agacgcggtc caggtgcggg ctgtggccga
     7921 gcagcttctc ggcgaggagc cccggcagcg gctggcagtc gaagcgggtg aggtcggcga
     7981 gctgggcgtc gagtacgtcg tgcagggccc ggcggacgac cgggtggtgc cggccgatgc
     8041 ccatcacgcc gaacccggcg agcatgtcga ggtagtcgtt gccctccgcg tcccagaagt
     8101 acgcgccctc ggcccgctcg tagaccttgt cgaagccgat ggtgtgcagc atgcgcggca
     8161 gctggtggtt gaggtggcgc gcgtgcaggt cgtaccgctc gtgcccgcgc tccgcgagga
     8221 gccgtttcag gtcgaagccc tggggcccgc cgtccgtcat cgcccgctct tctccttcac
     8281 tgcgtttgcc gagggggccg gctgcccggc cccctcaccg tcacgacgtc accggttgct
     8341 gctgatggtc tcccgtgccg cgcgcaggga ctccttcagc gaccccatgg tggcgagcac
     8401 cgccgtgggt tcgtagccgc agtgcgccat gcagttggcg cagcgcgggt ccttgccccg
     8461 gccgtacttc tcccagtcgg tctcctcgat gagctgacgg tacgtcggta cgtagccgtc
     8521 gctcatcagg tagcaggggc gctgccagcc gaagagcgag tagttgggga tcgcccacgc
     8581 ggtgcagggg aagtccgcct tgccctccag gaagtccagg aagagcggcg agtggttgag
     8641 ccgccagcgg gcccggttgc cgcccgcgaa ggccttcttg aagagttcgc gggtctgctc
     8701 gacgccgagg aagtgctcct ggtcgggcgc cttctcgtac gcgtaggcgg gcgagatcat
     8761 catctcgtcg accttgaggt cgtcgttgag gtagttgagg acctcgacga tggtctgcgg
     8821 ggtgtcggtg ttgaagaagg tggagttggt ggtgacgcgg aagccgcgcg ccttggcctc
     8881 cttcatcgcg gcgacggcct cgtcgaagac gccttccttg gcgaccgact cgtcgtgccg
     8941 ctgccgcagt ccgtcgatgt gcacggcgaa ggcgaagtag ggcgacgggg tgaacttgtc
     9001 gagcttcttg cgcatgagca tcgcgttggt gcagaggaag acgtacttct tcttcgcgac
     9061 gagctggcgc acgatctcgt cgatctgcgg atgcatcaac ggctcgccgc cggcgatgga
     9121 gaccatgggg gcaccggatt cgagcaccgc gcccactgcc tgggcgaccg gcatgcgctg
     9181 cttcaggaca ccggccgggt gctggatctt cccgcacccc tcgcaggcga ggttgcaggc
     9241 gaacaacggc tccagctcga cgatcagcgg gaacttctca cgcttgcgga gcttctgttc
     9301 gaagagatac gtcgcgacct tgatggactg acggagcggc atggccatct ggctcacctc
     9361 ctggggagca gtaaagatcg gtgccattcg taaaaagccg gtaggacggc acggagaaca
     9421 cggaaggccg atattccacc gcgtaccgtg ccgattcgga cgagctcatg ctctggagcg
     9481 tccacgacca cccggacggc cgcaaccggg cgcggcccgt ggcacagggc ggtacgcagt
     9541 gtggctgcgg attccatgtc caccgcgacg gccccggtgg ctcgcagagc ggcccgctcg
     9601 gggccgcgta cgacgtggtc ggagccggtg agcgggccgg tgtggacggt tgcgccgggg
     9661 gcggcccggg ccagggcggc gaccagcagt ccggtgccgg tgcagggcga ggcgccgtcc
     9721 gcgtcccggg tctcctcggc gacgaccagg tccccggggt gcatcccggg ggcgaggccg
     9781 gcgcagaagc cggaggcgat gacggcggcg tccgctaggc caccgggggc gagggccgcc
     9841 gccacggccg cctccgccgc ccgggggccc atcccggtcc gcaggacccg taccgggccg
     9901 ccaggccgcc tgccgctgcg cagggccagc tgctcgatgc ccagcgcgca ggcgaccagc
     9961 agcggcgccg gagggggcgc ggcccccggt gcgccggcca tcaggccccc tgggcggcgc
    10021 ccgtacggtc ggcgaacggg tcgccgtaca cgtagcgccc gagggccgtc agggggaaga
    10081 cctggcggta gaggtggtag ttgatggaga agtcccaggg gaagccggta ccggtgaaat
    10141 acggctcgtc ccaggagccg tcggcctgct gggcctcggt cagccaggtg accccgcggg
    10201 cgacggcccg gctgtcgcgg cggcccgcgg cgagcagggc gagcagcgcc caggcggtct
    10261 gggaggcggt ggactcaccg tgcccgatcc acttctcctc cgtgtacgag cgcaggtcct
    10321 cgccccagcc cccgtcgtcg ttctgcacgg actccagcca ggtcaccgcc cggcggatcg
    10381 aggggtgcgc ggcgggcagt ccggcggcga ccagcgcggg caccaccgac ccggtcccgt
    10441 agacgtagtt gacgccccag cgcccgaacc aggcgccgca cgcctcctgt tcggcgagca
    10501 gccactcgat gccccgccgg gtacgggggt gggcaccgag cccctcgacg gcgagcatct
    10561 ccaccacatg gccggtgaca tcggccgacg gcgggtcgat gacctcgccg aagtcgcaga
    10621 acggcaggcg gttggggaac gggctggtgt tgtcggcgtc gaacgcgccc caggccccgt
    10681 tgcgggactg catcccgagg ttccagcgca ccccgcgctc gatggcggct tccagccggg
    10741 cggggtcggg gtggcgcacc cggcgcagcg ccaggacgac ttcggcggtg tcgtcgatgt
    10801 ccgggtagtt gtcgttgtgg aactcgaacg cccagcctcc gggggcgagt tcgggtttgc
    10861 gtacggacca gtcgccgggc cgggtgatct cctcggccag catccagtcg gcggccttca
    10921 ccagcgccgg gtggtcgggt ctgagtccgc cgtcgaccag ggcgatggtg gccaggcagg
    10981 tgtcccagac gggcgactgg caggcctcga ccatccgggc gccgtcctcg cggtggacgg
    11041 cgaaccggtc cagcgaggcc aggcccgcct tcatcacggg gtggtcgagg tcgtagccga
    11101 ggaggtgcag ggcgatgatg gagtagacgg ccgggggctg gatgccgccc cagcagccgt
    11161 cgttctcctg gcgctccacg atccaccggg cggccacgtt catcgcgatc cggcgcagca
    11221 ggcgcggggc gaccttgtgg tagaggtgca gccccttgtc cagccgttgg aagaggccgt
    11281 cccaactggc cgccggagca agcttcctgg gcggattggg ctcggtggga tcggtgtgca
    11341 gctcgtccag ggcgaagggc gcgggccgca cggggcgctt ggcggagacg atggtcaggg
    11401 gaacgatggt ctggcgggcc cagcagccga agtcgtagat gttgagcggg acccacttgg
    11461 ggaagaacat gagctcgggc gggagttcgg ggaggtcgtc ccacttccac cagccgaaca
    11521 gggccagcca gatccgggtg aagacgcggg cggccgcgat gccgccctgt tccctgatcc
    11581 aggcggaggc gcgggccatg tgcggctcgt cggggcggtc cccggccagc cgcagggcca
    11641 catacgcctc gatggtggcg gagaggtcgc tcggtccgcc gtagaaggtg ttccaggtgc
    11701 cgtcaccgag ctgttcaccc cggatgaaga gggcggccgc ccgggtggtc tccgggtcct
    11761 ggatcccgag gaactggcgc aggagcaggt cctcggcgtc catcgtgacg ttggtggcca
    11821 gatcgccctt ccaccagccc tgctcgtcct gtcggccgag gagatgggcc acggagcgtt
    11881 ccgcggcctg ccgcgcggcg gcggtgacgt cgtccgcggc ggtggtcgtg tcggccggat
    11941 gcccggccgg ggccgcggaa aggttcgcgg ccccggtgga tccgtcggtc gtcgctgtca
    12001 tgagcttccc cttacgtgca gtggtttctc tgctgtgcgc tggggtctcc gtcgtgcggc
    12061 gccctggtca gggcgccgca cggcgactgc gagtcatata cgggtgctga tcaccgcttc
    12121 cgcaccacca cgaaatcggc gagcgcggtg agctgcgccc gtacctggtg cggcatgtcg
    12181 acggcgtgca gcgcctcgat ggccaccgtg tgctgacgac gggcttcctg cgcggtccac
    12241 tcgcggccgc cggcctcctc gatgagcgcc gcgcgggcgg cgaactcctc ttcggagaaa
    12301 ctgtcgaagt cactgctctt ggcgtcggcg gcgagcagtt cgccgagccg ctcggaggcc
    12361 ggtccgcccg cggcgagcgc ggcgacgacc ggcagggact tcttgcgctg gcgcaggtcg
    12421 ctccaggtct gcttgccggt ggcctccggg tcgccccaga tgccgagcag gtcgtcgacg
    12481 gcctggaagg cgaggccgag gtggtacccg tacgtctcca gggtgtcggc ggtgcggtcg
    12541 tcggcgccgc cgagcaccgc gccgatggag accgcgcagg ccagcagggc gccggtcttg
    12601 ttgccctcca tctccaggca ctcctcgacg gtgacccgct cgcggtgctc gtaggagatg
    12661 tcctgggcct gcccgtcgat gagcttgcgg gtggccgagg tcagccggcg ggccgcgcgg
    12721 cccgcctcga ccgtgccgag ctccagcagg acgtcgtagg ccagcgcgaa gagcgcgtcg
    12781 ccgaccagga tcgcctgggc ggggccgtgc accttccata cggtgtcgcg gtggcggcgc
    12841 tgctcgtcgc cgtccatcag gtcgtcgtgc agcagcgaga agttgtgcac gagttcgacg
    12901 gccacggcgc cggggacgcc cgcctcggcg ggggcgcccg ccgcttcggc cgacagcagg
    12961 gcgagcgcgg ggcgcacggc cttgccgccg tcgccgtccg agggccgtcc ctcggcgtcg
    13021 atccagccga agtggtaggc cgcgacggtg tccatgggcg gcgccagccg gtccacggca
    13081 gcccgcagga ccggcgctga cagggctcgt ccgcgctcca gaagcgcggt gacgtccgtg
    13141 gtctggtcca cggtgtcgga agccggattc gccggggtca ctgactctcc tcttgttccg
    13201 gtggtactgc tcatgccgcc tcctccagcg gatgtccatg ggggcggccg agatcgtgga
    13261 gggccgcgtc ggcggcctgg aagccgctgc gcacggcacc ctccatcgtc gcgggccagc
    13321 cggtggcggt ccaggcgccc gacaggtgga gtccgggcgc tcgcgtacgg gggccggggc
    13381 gcagcgcgcc gacgccgggg gcgggcgcga aggtggcggt gcgttcccgg gtgacgaaga
    13441 agtcccggat gcccgcgccg cgtgcggcgg gcaggagccg ctccagctcg ggcaggtagc
    13501 gctcgcgcag ctcggcgacg gggaggtcga tctcgtcctg gacggcggac tgggagaccg
    13561 ccagatactg cccggggccc ttgagccccg aggagtgcgt acggtcgaag acccactgga
    13621 ccggggagcc gatcgcggcg aagaacgggc ggcgcagcac cttgcggtcg tagatcacgt
    13681 gcacgttgag gatgggcgcg ttgtcgatgt cgaggagcag atccggctcg tccagggcgc
    13741 ccgcgggcag caggtcgtgg gtctcgtgct gcggtacggc gaggacgacg gtgtcggcgg
    13801 cgatccgctc ccccgcgctc tcgacgctcc agcggccgtc ctcggtgcgg gtcagggacc
    13861 ccaccttggc gcgcagctcg gtgcggacgc ccgcggtgtc cagggccttg cgggcgaggg
    13921 tgtcgtgcag ctcgccgagc ggcacggtgg cccagccgat gtcggcggcg ccgggctcgg
    13981 agagcagccc cgtcttgaag accttggcgg cgagcgccat ggaggcgttc ggcgcggtgg
    14041 cgttgagggt ggcgacgccg acgaggtccc agagcgcctc gatggcacgc tcggactggc
    14101 cgtgccgctt cagccaggtg gcgaagtcga tgcggtccag ggccgggtcg gcggggtcga
    14161 ggcggccgag cgcgagggcg gcgcgcccga cgttggcctt ctccgcgagg gagaggtgcg
    14221 gataggccgc gagaccgccg gccaggtgca gcggtacggg caggccggtg cggcggatgc
    14281 gtcccaggcg gggtccggcg gcgcggccga cgtccaggac ggggacgtcc aggcggtcct
    14341 ggaggggagc gaggtgggcg gcctcgatgc ggtcgaggaa ccagcggtag ccggtgcagc
    14401 agcgcaggta gacgtgctgg ccgttgtcga cggtgaggtc gccgcgctgg aaggagaagg
    14461 cgaggccgcc gaggcggggc cgcccctcca gcagggtcac ctccagcccg gcgtccgcga
    14521 ggcggagggc cgccgtgatg ccggcgaggc ctccgccgac gacgaccgcg acggggcgcg
    14581 gggtctcgtc gttcatgcct gcccctctcg ccgggccgtc ttcgatcgtc ggaccggcgc
    14641 cgacggccgg accgtcgccg atcgccggat cgtcccggaa ggaatcgtcg cagtcgtgga
    14701 cgcgtgcggc caccggaggg ttgaccgggc gccgggcgtg ccggagcgca tcaggcccgc
    14761 ccccgggagg tcaggcgcga gatgtggcgg gcgtccaggc cggagaggcc gcgcaccgcg
    14821 acgtacgcct tctcatggcc cgggagggag acccggccgc gcagcacggc ctccgggtcg
    14881 cgctcgatcc ggtccaggag acggcggtag atcccggcca tggcggcgac gcaggcgccg
    14941 ctgcggcggt cgagcatcgg cagcaggcgg tacccctcgg cgaacagggc ccgggcccgg
    15001 cgcacctcga agtggatgag gcccgcgaag tcggagccgg gcggcggggt ggtccggtgg
    15061 aatccggccg agcagccgaa cttggccagg tcgtcggcgg ggaggtaggt gcgcccgttg
    15121 gcggcgtcct cgcggacgtc gcgcaggatg ttggtgagct ggagggcgag gccgagggtg
    15181 tcggcgtact ccggggcccg ctcggcgccg ggtgcgcccg gttccgtacc gaagactccg
    15241 aggctgaggc ggccgatggc cccggcgaca cagcggcagt aggtcttcag gtcgtcccag
    15301 gtctcgtgcg tggcgccgcg gacgtccatc aggacgccgt cgatcagctc gtcgaggccc
    15361 tccagcggga gcgggaagcg gcgggcggcg tcggagagcg cgacggccac cgggtcggtg
    15421 tcgtcctcct cgaccttgcc gtgccggacc cggtcgagca gctcgcgggt gctctccagc
    15481 cgggtccgct tggtcgccgg gtccagctcg ccgtcgccga tgtcgtcgac gcggcgggag
    15541 aaggcgtaca gcgccgacat ggcctgccgc ttctcgtacg gcagcagtcg gatgccgtag
    15601 gcgaagttcc gggcctgctg tccggtgacg gcctcgcagt aactgtatgc ggcctgcacc
    15661 ggcggcgaca tgtacgtcgt ctgtccctcc acggtccagc tcacctctct ctacgcgctc
    15721 ttcgcaggac gactgcggct tcgcgcagca tgctgggctt ggtgggcttg ggtggccctg
    15781 gcaggacgtc gaatccggcg gccgagaccg cggtgagggc tgcgcggccg ccgccgacga
    15841 atccggcgag gaggagccgc agtctgccgt cgacgctcgc caccaggggg atgccgtcac
    15901 gcagcagctc gcccgcgcgt tcggattcgt acgcgatcag ggcgcggacc gaggctccgg
    15961 cggacggccg ggccaggtcg gcctcggtga cccggaagcg gtccatgtcc tcggcgggca
    16021 ggtagatccg gtcgcgggcg aggtcctcgg ccacgtcctg gaggtgctcg acgatctgga
    16081 gcgcggtgca gaccgcgtcg gagaggcgca cgcgctccgg gctcgtggtg ccggtgaggg
    16141 cgaggaccag gcggccgacc gggttggcgg agagctcgca gtaggcggcg agctctccgt
    16201 aggtggcgta gcggcggacc ttctggtcct gccggttggc ctcgatcagg ccgaggaagg
    16261 gttcgggggt gagcgcgcgg cgccgcacgg tggggcgcag ggcgcgcagc agggggtggt
    16321 gcggctcctg gccggtggtg gcgaagaccc ggtgcaggtc cgtctccaag gcgtcgagca
    16381 tggcgagccg gtcgttgctc tgctccggct ccaggcccag gtggcgggcg tcggctccgc
    16441 cgggggcgag gtcgccgtcg ccgatgtcgt cgacgagccg ggcgtagccg tagaccgcca
    16501 tcaggtcccc gcgccaggcg cggggcagga agaagggggc cacggggaag ttctcgtccg
    16561 cggccttgcc gagcgtggcg tcgccggtgc gcgcctcggg ggtggaggtc actgcggacc
    16621 gcccggcgcg gggacggcgg aaccacgtcg gagctggaga ttttccgtca ttgccgtcac
    16681 atctcccgtt ctacactgct gacccaaaac atcccttttc ggacacgccg ctcgttcttc
    16741 cgagtgcact gcggcacagc gggcggagcg ccgggggcgt atcgccccac ttgccatgaa
    16801 tcagcaccgc tacagcttac gttgtacagc tcacaggggt gcgccggggt gaggcgcccc
    16861 gggcgcggac accgcgccac gcgtcaacct tgctcgtacg caggtggatt gacgtcatcc
    16921 gccgggagga gatcatcccc ggctccctac tgcgggtggc ctccccggac cccgtacagc
    16981 gctgtggccc ccaccggagc ggtccggcgg aggccatatg gctgggaaac tacttgcccg
    17041 tctcgcgttc gtacgccttg aggacttcct cggtggggcc gtccatcagg agttcgccct
    17101 tctccagcca gagcgcccgg tcgcaggtgt ccctgatcga cttgttgttg tggctgacca
    17161 ggaagacggt gcccgcctcc ttgcggagtt cacggatccg cgcctcggag cggacccgga
    17221 acttgtggtc accggtggcc agcgcctcgt cgatcatgag gacgtcgtgg ttcttggcgg
    17281 cggcgatgga gaagcgcagg cgcgccgcca tgccggagga gtacgtccgc atcggcaggg
    17341 tgatgaagtc acccttctcg ttgatgccgg agaagtccac gatctcgtcg tagcgctcgc
    17401 ggatctcggc ctggctcatg cccatggcca gtccgcccag caccacgttg cgctcgccgg
    17461 tgaggtcgct catcagcgcc gcgttgacgc cgagcagcga gggctggccg tcggtgtaca
    17521 cgcggccgga ctcggtcggc agcaggccgg cgatggcccg cagcagcgtc gacttcccgg
    17581 agccgttggt gccgatgagg ccgatggcct cgccgcggta ggcggtgaag gagacgccgc
    17641 gtacggcgtg caccttccgc atcccgcgcg gctcgccctt gccgcggcgc atcatgcggc
    17701 tcagcgcggc ggtggcgctg ccccggccgc cgccggtgcc gttgacgcgg tagacgatgt
    17761 ggacatcgtc ggcgatgacc gtgggaatcc gtccctgcgt gttgtcctca gccacggccg
    17821 taccgttcct ctgccttcca gaagtacacg aatcccacga cgcccagcag gacggcccag
    17881 gccaggccgg cggcccagac gtggtccggc aggttctcgg agccgtagcc gtcgatcagg
    17941 gcgaagcgga ccaggtccat gtagatggcc gccgggttgt actggagcac gtcggcgatc
    18001 caggccggct tgtccttgag catcaccggg atggagaaca tgacacccga ggcgtacatc
    18061 caggtccggg tgatgaacgg catcagctgc gcgaggtcgg gggtcttgga gccgagccgg
    18121 gccatgacga gggcgaggcc ggtgttgaag aagaactgga ggatcagggc ggggatcacc
    18181 aggagccacg acagcgaggg gtagctgccg aagatgatgg cgaccgcgac cagcacgatc
    18241 atcgagaaca acagctgctg gagctgctgg agcgagaagg agatggggag cgaggcccgg
    18301 gggaagtgga gggcccggac cagtccgagg ttgccggaga tcgaccggac gcccgccatc
    18361 acggagctct gggtgaaggt gaagacgaag acgccggtga ccaggaacgg cacgaagacg
    18421 tcgtgcggga tgccctccct ggtccccagg atcagtccga agatcaggta atagacagcg
    18481 gcgttcagga gtggggtgac cacctgccac agctggccca gtttggcctg gctgtactgg
    18541 gcggtcagct tcgcccggga gaaggccagg atgaagtggc gccggcccca gagctgtcgc
    18601 aggtaggcga gcagccccgg ccgggcgccg ctcacggtca ggccgtactt cgcggccagc
    18661 tgggccgcgc cgaggccctc gtcggcggac ggcggggccc cgagggccac cccaccgtcg
    18721 tgggtcgtgt cactcacaag ttgaaactct cgtcttcacg cgcagccagt cgcgggcgcg
    18781 gctcaggcgg acaggtcccg gaaagaaaat acgcctcatg ctctcagagg aaagcttctc
    18841 agatgaccgg aggtcgtccc agccgcgtca gccgccacac cgtacgccac ttcatcgggc
    18901 ggcgcggtcc gcagggggtc gcccagcctt cccggaagcc gccgaaccac gccttcagcg
    18961 cgggcggcga cgggcgcctg accagggtca gcagcagcca gaccccgaga tagaggggga
    19021 ccagcggggc gggcaggttg cggcgggcca gccagacccg gttgcgggcc accatgcggt
    19081 ggtggaccgc gtgccgggag ggggccgtgg tggggtggtg gagcaccagg tccgcgcggt
    19141 agtcgatcat ccagcccgcg tccagcgccc gccaggcgag gtccgtctcc tcgtgggcgt
    19201 agaagaactg ctccggcagc gggccggcct cggcgaggac ccgggtgcgt acggcgttgg
    19261 cgccgccgag gaaggtcgtc acgcgggatg agcgcgtcgg gtcggccgcc cggagccggg
    19321 gcacgtggcg gcgctgggtc gcgcccgtgt ccgggtcggt gatccggaag gtgatgatgc
    19381 cgagcctggg gtccgccgcg aacgcctgcc ggcagagctc ggcggtgtcc cggcccggga
    19441 gcagcccgtc gtcgtcgagg aagagcaggg cgtcgacgtc cgcgccggac gggccgaacg
    19501 cctcgatgcc gacgttgcgg ccgccgggga tgccgaggtt ctccggcagc tccaccgtcc
    19561 gtacaccggc cggtacggac cccaccgggg ctccgttgcc gaccaccacg acctcgatcc
    19621 ggtcaccctc ctgcgcgatg accgaatcga ggagggcgcg gagctcgtcg gggcgatcgc
    19681 ccatggtgat gatcaccgcg cccagtttca tgggtgaggt cacttcagcc tgctggacgc
    19741 caggacggag accaggtgca gcagggtctg gaggagtgcg atgccggcca ggacggcggt
    19801 ggccagacgg gtgtagaaga ggtcgccgcc gatcgtgtcc aggatcgcca ccagcaggat
    19861 cagcagcgag gcctcgatgc cgaggatcag ccggtggaac ttgagcgccc cggccgcccg
    19921 gcgggccagc gccatcccgg aggagcgcgg ctcggaggcc gcctccttca ccggcggcag
    19981 cccgccctgg tggcgggcga cgccgaccag gtccgtctcg gccttgatca tgatcgcgcc
    20041 gagcgcggcg agcgtcccca ggaacgccca gagccagtcg atccggccct cgccccagat
    20101 gtcggcggcg cgcaggccga ggccgacgag caccgccgcg tcgcacaggt aggcggcgac
    20161 ccggtccaga tagacgccgc tgagcgagta ctgcttcttc cagcgggcca gctccccgtc
    20221 cacgcagtcg aagagcaggt agagctggac catcagcacg ccgagcaggg cgccgggtat
    20281 accgggcacc agcagggcgg gggcggccag gaccccggcc agcgtcatga cgtacgtgac
    20341 ctggttcggg gtgaccttgg tgttcaccag gtagcggtcc acccgcaggg agacctcccg
    20401 catgtacatg cggccggccc agtgctcgcc gctgcgccgg tccttgaccc ccggggggtg
    20461 cacgaccggg cggagttcag ctactgatgg tcgaggcata gtcggcgtac gcgtccctga
    20521 tctggtcggt ggacaggctg aggtgttcca ggacggtgaa gcgtcccggc cgggtctgcg
    20581 gcgcgtagtc gacggcccgg acgaactcgt cgacggtgaa cccgatctcc tcgggcagca
    20641 ccggcagacc gtggcggcgc agggtcgatg ccatcaggag ggcctcctgg cgggcaccgc
    20701 gcagatgcat ggcgaagcag gcgccgaggc cgacctgctc gccgtggctg gccgcacgct
    20761 gggggtacag caggtcgaag gcgtggttga tctcgtggca ggcgccggag gcgggacggg
    20821 agtcgcccgc gaccgacatc gagatgccgg tcagcacgag cccctcggcc agcaccttga
    20881 gaaaggcgtc gtcgccgacc ccgccggggt ggcgcagcac ggcctcgccg gcctggcggg
    20941 ccatggcggc cgcgagaccg tctatctcct cgtcgttgac ctcgtgggcc agctcccagt
    21001 cggcgacgca ggagatgttc gagaccgcgt caccgatgcc ggaacggacg taccgggcgg
    21061 gcgcctcacg gatcacgtcg aggtcgatga ccacggcgat cggggtgggg accccgtagg
    21121 agccgcgtcc gttgtcgttg tccagggtgg cgaccgggga gcacaggccg tcgtgcgaga
    21181 ggttcgtcgc gacggcgacc atgggcagcc cgacccgcgc cgcggcgtac ttcgccacgt
    21241 cgatgatctt gccgccgccg aggccgacga ccgcgtcgta ccgggtgccc ttgatcccgt
    21301 cggcgagctt caccgcggag tcgatcgtgc cgtcggcgac ggcgtaccag tcggcacccg
    21361 gcaggaccgg ggcgagcctc tcccgcaggg cgcgaccgga gccgtcgctg atcgcgatgg
    21421 cgagcttgcc cgaggaggag atccgctgat cggccaggag acccgccaga tcgtccatgg
    21481 cgccgcgccg gatgtcgacg acgaccgggg acggaatgag ccgggtcagt actggcacgc
    21541 gatctcccgg cccttctcga ggtcgtcgtg gttgtcgatc tcgacccagg tcacggtgcc
    21601 gatgggggcg acgtcgacgg tgaagccgcg gttcacgagc tcctggtagc cgtcctcgta
    21661 gtagaggtcg gggtcgcgct cgaaggtggt cttcagggcg tccgcgagct cctcggcggc
    21721 ctcggcctcg atgagggtga cgccgatgta ctcaccggtg gcggtggccg ggtccatcag
    21781 cttggtgatg cgctggacgc ccttgccctc ctcggtgatg accttcatct cctcgtcggc
    21841 caggctcttc tcggtgtcca gggcgaggat gatcttctga cccttgccgc gggcgtccag
    21901 gagggtcttc tcgacggaga ccgggtgcac ggtgtcgccg ttggcgagga tcacgcctcg
    21961 cttgaggacg tcacgggcgc accacaggga gtaggcgttg ttccactcct cggccttgtc
    22021 gttgtcgatg agcgtgagcg tgaggccgta cgtcgcctcc agctcggcct tgcgggcgta
    22081 gacggcctcc ttgcggtagc cgacgacgat cgcgacctcg gtgagtccga cctcggcgaa
    22141 gttggcgagc gtgaggtcga ggaccgtctt gtcgccgtcc accgggacga gcgccttggg
    22201 gagcgtgtcc gtgtaggggc gcagacgtcg tccagcaccg gctgccagta cgaggccgat
    22261 catgcgagtt ctccttcgtc gtgtacggcg ggggccgagg aggacaccca gaagcggatg
    22321 gactccacga gcaccaccag agccacggcc accgcgaggg cggtgagagc cgtggtgaaa
    22381 cctgaggtgt gggtgagtga ggcggcgagg acggccacca gcgcggtgcg gccctcgtgt
    22441 cccccgatcg tccgcaccag ccactggggc ggcgcgccgg tgcctccgcg gatgcggtac
    22501 accgtgtcgt agtgatggta ggcgacggcc gaaacgagcc cgaaggccgc cggaacggcg
    22561 tgcgggacgt cgctgcgggc cgcgagcacg aggatcgtga cgtactccgc gacccggaag
    22621 aacggcggca ccagccagtc gagcgcccgt ctgagcgggc gggccacggc gaagccggag
    22681 agcacgacgt agaccgccgc ggcgacgacg gtgagccagc tgccgtacgg gaggaagagc
    22741 gcggcgccga ccatcacgag ggtgccgatg agggcggcgg ccggggctgt cagcgctctc
    22801 ttcggaccgt ggacgagcga ggcgacggcc tgggccaggg ggccggagtc ggcgaggtcc
    22861 gccagcgccc gtgccgcgcg ctcggtacgc cgggccttgc gggtcaccga gcgcaggagg
    22921 cgccccacca gggtgtaggt ggcggccagg gcgcagccga tgagcagggc gtagaagacg
    22981 gtgcgggggg tggtgagcgc ggtgagcacg gcgatcatgg cccagcgttc gccgatcggc
    23041 agaacgatta tccgccgcac ccacaccgtc cagccgacgt tgtcgagcgc gtcggagagg
    23101 gcggcggtgg ggctggtgtt ggcgaccgag tcgtggttgg cctcgttgaa ggagaagtcc
    23161 acgatgtggc ggcaggcctg gaggaccatc gcgccgagcg ccaggaccca tacgtcgtcc
    23221 ccgccgcggg cggcgccgat ggcgagcccg gcgtagtagg cgtactcctt ggcccggtcg
    23281 aacgtggcgt ccagccaggc gcccatcgtg gagtactgga gcgagtagcg ggcgagctgc
    23341 ccgtcggtgc agtccaggac gaaggagacc aggagcagga tgccggcggc gatgtagccg
    23401 ccccgggtgc cggtcgccgc gctgcccgcc gcgatgagcg cggtgatcag ggaggcggtg
    23461 gtgacctggt tcggggtgag gccccggcgg gcgcaccagc gggcgatgta gcgggagtag
    23521 gggctgatgc agaaggtggt gaagaacccg tcgcgggact tgaccgcgtt gcgcagccgt
    23581 accgcctcgt cgtcgaccgc gacgagcccg gccacggccg cggcctcctg atcgcggtcg
    23641 gtgggtacgg ccgcgacgag cgagccgagg gcggggcgct gtacggcgat gccctcggcc
    23701 tccagctcga cggcgatgcg gccggggacg gtggggtccc cgggtgccgg gccggcgccc
    23761 gggtcgacgg cgggggcgcc cgcgccgacc gcggcggtgg cgcgctccag cgcgcgcacc
    23821 agtgccggcc gggcctgggg ctgggcggtg agcgcaccgg tgacggtggc ggcggggaag
    23881 cgcgggtcgg tcagcccgag ccgcagcgcg tggaggtggc ccaggaagcg ggggtcgacg
    23941 agggcgacgc ggtggtcggc cgggacgtcg gcgaggagtg cggcggcgtc accggcgtcg
    24001 gcggcactca ccacgtcgaa gcccagggcc ctcaggtcgt ccgcgagcga cgacccgggt
    24061 accggcgtac cggtgaggat ggcggtcgac agacgaactc actccttggc actgacggtg
    24121 gacgacactc ggcagcacgg ccacgaggcg ggccggcggc gtgtcggctg aggctatcgg
    24181 atgaacggac gaccgggttc accacccgtt cgcgcgccgt tcgggtgcac gggatggtcc
    24241 gggctccctc gtcgatcatc atcatcgatc ggtggcccgg cccacaaacc gccggtcgga
    24301 ccgggtgagc cgggcgctta ggctgacggc catgacgtgg ctgatcacag gcggagcggg
    24361 atacatcggg gcacatgtgg cgcgggccat ggtggcggcg ggaaagcggg tcgtggtgct
    24421 cgacgaccgc tccagcggca tcgtggaccg gctgccggag gccgtcaccc tggtggaggg
    24481 ctcggccggc gaccgggagc tgctgggccg ggtgctcggc gagcacgcgg tgagcggtgt
    24541 ggtgcatctc gcggcgaaga agcaggtcgg cgagtccgtg gagaagcccc tgctgtacta
    24601 ccgggagaac atcgccgggc tgaccgtgct gctggaggcc gtggtcgcgg cgggcgtgcg
    24661 gcgcttcctc ttctcgtcct cggcggccgt ctacggcgta ccggacgtgg agctcatcac
    24721 cgaggagacg ccctgcctgc cgatcaaccc gtacggggag accaagctcg ccggagagtg
    24781 gctcgtgcgg gcgacgggca aggcccacgg gatctccacc gcctgcctgc gctacttcaa
    24841 cgtggcgggc gcggccgggc cggagctggc ggacaccggg gtgttcaaca tcgtcccgat
    24901 ggtcttcgac cggctgacgc gcggtgaggc gccccggatc ttcggcgacg actaccccac
    24961 gcccgacggc acgtgcatcc gtgactacat ccacgtcgcc gacctggccg acgcccacct
    25021 cgccgtcgcg cggaagctgg gcgtgcgcga gggcggcgat ctgacgctga acgtcggccg
    25081 gggcgagggc gtgtcggtac gggagctgat cgacgtgatc cgcgaggtgt ccgggcaccc
    25141 ggtggagccg ctggtggagc cgcgccgccc gggggacgcg gcgaaggcgg tggcctcgga
    25201 cgcccggatg gtgcgggagc tggggtggac ggcccgccgg gacgtccgct cgatggtgga
    25261 gtcggcctgg gaggggtggt gcctgcgcca tccggaggcg cgtaccggtg cccggggcgg
    25321 acgcgaggcc ctggaccaac gcccgtaaac gatctcgtca gcgctctgac ctgcgtaacg
    25381 tttccgcagg tcagagcata tgacaacggt gttcagtgcc gtgttgcccg atacccccca
    25441 cccgtagttc actggcgtcg tcgggcggtt tcgccgggcg ctgtcgcacg gacacgggag
    25501 gcgtttcgca tgggggctgg ccacgatcac gggcacacac acggcgggcc gcccccgacg
    25561 ggcacggcgg ccgccgcgta ccggggcagg ctccgggtcg ccctggggat caccctgagc
    25621 gtgatggtca tggagatcgt cggcggggtg ctctccgact cgctggccct gatcgcggac
    25681 gccgcccaca tggccaccga cgccctgggg ctcgggatgg cgctgctcgc catccacttc
    25741 gccaaccggc ccgccggccc gaaccgcacc ttcggcttcg cccgcgccga gatcctggcg
    25801 gcgctcgcca actgcctgct gctgctgggc gtcggcggct tcctgatctt cgaggcggtc
    25861 gaccggttca tcacgccggc cgagaccaag ggcggcctcg ccatcgcgtt cgccaccgtc
    25921 ggtctggtgg ccaatgtcgt ctccctctct ctgctgatgc gcggacagaa ggagagcctc
    25981 aatgtgcgcg gcgcctatct ggaggtgatg gcggacaccc tgggctcgat cgcggtgatc
    26041 gtctcggcgg gcatcatcat ggcgaccggc tggcaggccg ccgacccgat cgcctccctg
    26101 gtgatcggtc tgatgatcgt cccccggacg gtcaagctgt tgcgggagac cctgaacgtg
    26161 ctgctggagg cggcgcccaa gggcgtggac atggcggagg tacgggccca catcacggcc
    26221 ctgcccggcg tcctgggcgt ccacgacctg cacgcctgga cgatcacctc ggggatgccg
    26281 gtgctctccg cgcacgtggt ggtgcgccag gagatgctcg actcgatagg gcacgagaag
    26341 gtgctgcacg agctgcaggg ctgcctcggg gaccacttcg acgtggagca ctgcaccttc
    26401 cagctggagc cgagcgggca cgcggagcac gaggcgcatc tgtgccactg agcaccacgg
    26461 ggcggtgcgt ggcggcggtg ctagggttgt cagcgttgtt tcgctgagac gttcgagtct
    26521 cagcggtgga cggcccgggt ggaccgggac cctctcgaga ggagctgagg ttgatgacgg
    26581 tcgcgacgac gccttcccgg cgcggcaatc gt
//
