LOCUS       NZ_KB891300            24439 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces sp. ScaeMP-e10 B061DRAFT_scaffold_12.13, whole genome
            shotgun sequence.
ACCESSION   NZ_KB891300
VERSION     NZ_KB891300.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. ScaeMP-e10
  ORGANISM  Streptomyces sp. ScaeMP-e10
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 95473)
  AUTHORS   Stepanauskas,R., Sieracki,M., Masland,D., Poulton,N., Swan,B.,
            Garcia,M.M., Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C.,
            Tapia,R., Chen,A., Kyrpides,N., Mavromatis,K., Markowitz,V.,
            Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G., Pagani,I.,
            Pati,A., Goodwin,L., Nordberg,H.P., Cantor,M.N., Hua,S.X. and
            Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Improved High-Quality Draft of Streptomyces sp. ScaeMP-e10
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 95473)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
REFERENCE   3  (bases 1 to 95473)
  AUTHORS   Stepanauskas,R., Sieracki,M., Masland,D., Poulton,N., Swan,B.,
            Garcia,M.M., Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C.,
            Tapia,R., Chen,A., Kyrpides,N., Mavromatis,K., Markowitz,V.,
            Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G., Pagani,I.,
            Pati,A., Goodwin,L., Nordberg,H.P., Cantor,M.N., Hua,S.X. and
            Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. ScaeMP-e10
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            Isolation Site                    :: Gulf of Mexico
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 03:00:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,185
            CDSs (total)                      :: 7,109
            Genes (coding)                    :: 6,996
            CDSs (with protein)               :: 6,996
            Genes (RNA)                       :: 76
            rRNAs                             :: 6, 1 (5S, 16S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 45 of 113
            Pseudo Genes (incomplete)         :: 82 of 113
            Pseudo Genes (internal stop)      :: 12 of 113
            Pseudo Genes (multiple problems)  :: 23 of 113
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:33:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 52689
            Orig. end                         :: 77128
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB891300.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405355
            Source DNA and Organism available from Cameron  Currie
            (currie@bact.wisc.edu)
            Source DNA available from Cameron  Currie (currie@bact.wisc.edu)
            Organism available from Cameron  Currie (currie@bact.wisc.edu)
            Contacts: Cameron  Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24439
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..24439
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24439
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14439](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14439
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(198..213)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.33"
                     /tool="antismash"
     gene            complement(248..1582)
                     /gene="lysA"
                     /locus_tag="B061_RS0116305"
     CDS             complement(248..1582)
                     /EC_number="4.1.1.20"
                     /GO_function="GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene="lysA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743208.1"
                     /locus_tag="B061_RS0116305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diaminopimelate decarboxylase"
                     /protein_id="WP_018512600.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 7e-65, bitscore:
                     211.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.2e-19,
                     bitscore: 63.2, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPPLTEFAAGPSDLSVWPASTTRLPHGQLTVGGVQLADIADRF
                     DTPAYVLDEDEVRTRCRTYRAAFPDADVLYAAKAFLSRAMVRWIEEEGLGLDVCSAGEL
                     ELAHAAGFPPERMVLHGNAKSPRDLETALRLRVGRIVVDSPSEIARIAALVGPRGRQKV
                     MVRVVPGVSAGGHEKIRTGTDDQKFGLSLTDGSAQHAVARVLGQSQLELTGLHCHIGSQ
                     ISDVKPYLVAVRRMVGLMARIRNSHGTTFAELNMGGGHGIAYRPGDPALDLTSLARRLR
                     AELAASCAAAGLPVPRLVIEPGRAIAGPAGVALYRVLAVKHTGGTMFVAVDGGMSDNPR
                     SALYGARYAPHLISARPKAERVVATVVGRHCEAGDVLASDVPLPGDVRPGDLLAVPVAG
                     AYHLSMASGYNLVGRPPIVAVHEGTARLLVRRETLQDLRGRDVGD"
     gene            complement(1621..1950)
                     /locus_tag="B061_RS0116310"
     CDS             complement(1621..1950)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010058602.1"
                     /locus_tag="B061_RS0116310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAV_915 family protein"
                     /protein_id="WP_018512601.1"
                     /transl_table=11
                     /translation="MCLFLYDDPDPDEQDPAGLLHVPAHRVATGFVLRTFRTPLGERTA
                     VAFTHRDLLARTLGAGQPSIRLAESALRSLASPLGISRLVLDPVLSAPAVSAEPLCADA
                     TVATL"
     gene            2150..2662
                     /locus_tag="B061_RS0116315"
     CDS             2150..2662
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571117.1"
                     /locus_tag="B061_RS0116315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="universal stress protein"
                     /protein_id="WP_018512602.1"
                     /transl_table=11
                     /translation="MRQRIVVGVSGSLGSLTALHQAASEARERGAELYAVLAWQLPGGG
                     LGSRTTLGVETFRECRAAAREELCTALDLAFAARRPGVTLSGFTVRGEPGAVLVDAVRS
                     ADDLLVVGTGLRGRWLSGLRAPVARYCLTHAPCPVLAVPPNPLEAELAEVRRTGWHLPF
                     MEREPER"
     misc_feature    complement(2933..2942)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            3121..4311
                     /locus_tag="B061_RS0116320"
     CDS             3121..4311
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140714.1"
                     /locus_tag="B061_RS0116320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018512603.1"
                     /transl_table=11
                     /translation="MKANRGLLGDERRDRGLELPPTRGVLIAGGLVRVSGGAAAGCGAL
                     FGLLPVLALIGRFGLPDDPPAFVPVFGGTLLAASFGITIFLMVFGYALTFHQLALADMY
                     AAAADAPSLRNAVEVRGPVSRTPFFPAVVTSVVIGSLLLATAGILLAASAWPAIARTLL
                     VLGVLCVPLVLALIAAGRRWARSAGERLPAQALGEQGPARLLIGDVDTKLRQQVKARNR
                     AEATRLDRTNIPVLATFVIAVLAMMTPSLSPTTVLWKQVQLGGAGLAALWLFLVPCIAV
                     LRAWQLRRTLARVRRGGVDVTAVDRAHAITATTTQAAELHAAAAVWTLLGAGALGTMVP
                     RTAAVAPVIIVAGSWAFGLAALLVLSMRSDAAAPKLREEFGYRLPSQTSGNDNTWH"
     gene            4478..4813
                     /locus_tag="B061_RS39225"
     CDS             4478..4813
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /locus_tag="B061_RS39225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="WP_106435306.1"
                     /transl_table=11
                     /translation="MGQAVNRRRVARLMREHGIQGVTRRKRRSLTRADKKARPPPDLIG
                     RELPAEMPGTKLVGDITALPTGEGWLYLACWLDLATREVVGYSMADHHRADFVTWPTAA
                     VDCNPAE"
     gene            4810..5115
                     /locus_tag="B061_RS39230"
     CDS             4810..5115
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF025063.4"
                     /locus_tag="B061_RS39230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="integrase core domain-containing protein"
                     /protein_id="WP_106435307.1"
                     /transl_table=11
                     /translation="MIHSDRGSEYTSTRFQDRSRELELRQSCGRTGSCFDNAAAESFWA
                     LLKEDIGTRVWPDRATARADVFDFIETFYNRRRQRRHKVFGYLTPTETRQRHTLAA"
     gene            complement(5271..6917)
                     /locus_tag="B061_RS0116330"
     CDS             complement(5271..6917)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512604.1"
                     /locus_tag="B061_RS0116330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VanW family protein"
                     /protein_id="WP_018512604.1"
                     /transl_table=11
                     /translation="MGAGFGGLYLVGLFVADDTVPAGARVSGVDIGGLSTAQARERLDS
                     GLGKTWSEPVKVRLGDSDGTVRVSGISLDTEETVARAAQPGADPFTVIGRLFANGDREV
                     EPVIRVDAVKARASLAEKAKSYDRKAREGAVRFKVGEPVLVRPVTGRSLDVDGAVERLA
                     EEIPGQGAGPVRLPVRTTEPQVGAAEVERAMEEFAIPAMSAPVTLTVNGRKIEIGPAAL
                     GKHLAMKPDGDKPLAPVLDGEGLLVEPSVASALALALDEPANAELSVHGGRVAVASDGR
                     TGQDVTAVGLKKAVLPLLTKSGAARTGAVGVKEVEPTLTRDNLGRLGITEQMSTFTVDF
                     EPDAYRVTNIGRAAELINGSVVQPDGIWSFNRTVGERTEANGFVEGVIINNDRYEKAAG
                     GGVSAVATTVFNALFFAGVKPVEYGAHSFYIERYPEGREATVAWGSLDLKFRNDSGNTI
                     YIDARATNTSVTITFLGTKRYDEIESVKGPRTSVKQPTTREGASGESCVPQTPLEGFNV
                     SVDRLFKDGGRTVRTENFETRYDPRDEVTCD"
     gene            complement(7146..>7862)
                     /locus_tag="B061_RS40185"
                     /pseudo=""
     CDS             complement(7146..>7862)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044646.1"
                     /locus_tag="B061_RS40185"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="WRGVPKRYGPWATLHTRFRRWAADGTFHRMLRAAQAKADAAGDVA
                     WLVSVDSTRRPGSPACGRGSKRGLCDPALGWSRGGLTSKIHLTCDGRRRPLAFVVTGGS
                     TNDYTRFIAVMEAIPGARIGPGRP"
     gene            <7873..7988
                     /locus_tag="B061_RS38370"
                     /pseudo=""
     CDS             <7873..7988
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018522315.1"
                     /locus_tag="B061_RS38370"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="response regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="YTSHANAYVTKPVNLDAFEQAVQSIDASTSTPPRDRTR"
     gene            complement(8766..9245)
                     /locus_tag="B061_RS0116340"
     CDS             complement(8766..9245)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B061_RS0116340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158689954.1"
                     /transl_table=11
                     /translation="MAAVRSCRWILTDELAEAYGKFAEEPTRPKLERAGGTRAVGRAGG
                     GGAAHFPLHPADLSTTGVALSAGTTDLCLLLALGMLLRNAVPAVALGIIFTGLLAAAHV
                     INPKATTTLATALHAGGILDTLAAALAALVCPLALARGRQPDHVSTRPTARSGRA"
     misc_feature    9542..9557
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.25"
                     /tool="antismash"
     gene            9663..9893
                     /locus_tag="B061_RS39525"
     CDS             9663..9893
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B061_RS39525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_109981233.1"
                     /transl_table=11
                     /translation="MLDTDPTPGGAVDLVVGDADESWEDLVRDLIAGPADPSRILTDCG
                     GNGCNCAGCVGCGLNCMSGGWKCATCGSACC"
     gene            10001..11308
                     /locus_tag="B061_RS0116345"
     CDS             10001..11308
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964458.1"
                     /locus_tag="B061_RS0116345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YcaO-like family protein"
                     /protein_id="WP_051104647.1"
                     /sec_met_domain="YcaO (E-value: 1.8e-62, bitscore: 204.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 5.1e-82, bitscore:
                     268.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDLNDVNMKQLDPLLSRYGVVGDAFDLSPSRYRGLPELSSYGVD
                     LGSGFPGLEARPDDRVVAGGHALGDKDRARLLAIAEGCERYSGAQFGTEGVVTAAAHDL
                     DGRVLDWSRVPRLSDAEYAHPRCPLVPFDPAAPIRWVRGVDLRDGDPTWLPLSMAAYRS
                     GRRLPAERFVASISTGCAVHTDPASAVFGGLSEVVERDMIAVLWLQKLPLPHIPFDVLD
                     ERELTVVEWAHDRFLDTVLLDATSDIGVPTVYCMQTAPHDQTIRTMVGCGTGLTIQDAA
                     YKALLEVTCFRDSLHVEWEEPESFADYTDISDGAKYMGKPENAPHFAFLTDDHPDRPSF
                     QDRGRYAADATEGLTRAVRRFAELDMAVIAVDRTTTELASVGLHSATVVIPDLQPMSLV
                     PLAQYHAHHRLYSAPAAMGYRVLPVEELNPCPQPFA"
     gene            11287..12009
                     /locus_tag="B061_RS0116350"
     CDS             11287..12009
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964457.1"
                     /locus_tag="B061_RS0116350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_018512608.1"
                     /transl_table=11
                     /translation="MSAAVRLTRLSVLGTGAFGARASELLPEISGLAVTQVGPEITCDM
                     LVDADAAVLVLDRPARRLARRFRQVASEAGKPWLLVEFDHPVIRVGPYFDPAAGPCLDC
                     FYAREDQHADKPAPLRKPVPGHEHTHEHNHGHAHAPDCSHASAPASAEEGLGVEAAAGV
                     LPHQARIAAGLLSLSLAEQVRGRVVTVDLRTAAVRSDQVIGCHGCPHCGDETQRTLMSR
                     QLDHLFRTVGGVTHDEHR"
     gene            11993..13702
                     /locus_tag="B061_RS0116355"
     CDS             11993..13702
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964456.1"
                     /locus_tag="B061_RS0116355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_106435308.1"
                     /transl_table=11
                     /translation="MTSTDSFPPGGLRPRLRGGVAVSAADGQVVFSAGQIRKRIGGGDA
                     LRLLLPIASAMDGRRTVGDLAEATDLPYEAVAQAVALLVKQGLVLSGEVSSPKPLAAGV
                     VDYLEQTAGSSATFRDASEVLERLSRCAVLIVAPPGHTEAVRADLARSGVGTVHSASTP
                     AGVGNEVLDSLREAAGSLVVLYGPPRHDDGTDSFTDDCAARDIAVLHYAAHQGQVDLGP
                     LVHPRATLCRRCFTSGYLAEFGSEQPAPADTATGTVAAGLVVGEALAYLADVDSMRTSQ
                     ALVRWTLPDSTAVRYAVSAEADCASCATTSRRSGERATVLEAYEDVVAAQPLADRPQPP
                     VTAGREKRLTALGKERESFPTAPVIPLPPPPATASAAPTGDEVPAVSEAGPSGTVGTAD
                     AAFVADLAAMVAGRRGDGGPRRWTASGGGLASVELYLMCADTVSGLPAHTLLKYDDIAH
                     RLLVTRRTHGPGLWRSMLDATGLTETPDVVLVVVGALWRLKLKYSTFGIRLGHLDAGCA
                     LAQLHAVATDRGARVTLNDRWQPTLPTLLELKEDEQVMAVAGLWTPRSARCP"
     gene            13693..14439
                     /locus_tag="B061_RS0116360"
     CDS             13693..14439
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964455.1"
                     /locus_tag="B061_RS0116360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitroreductase family protein"
                     /protein_id="WP_043185298.1"
                     /sec_met_domain="PF00881 (E-value: 4.8e-15, bitscore: 48.7,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLINETDLWSLAKRALAPADRPDERTPPGGPSAQDTSRTSPASR
                     ISRSVPLHDVLTARRSVRRFRQDPVPDTDLATLLDLATSTDRQMWPHGTAATTPQAWLV
                     SGVTGTSGARLRQYISRRSTAGQTTAGEFTDRGDSPEPALLATRYAPAPVTILICAQIT
                     DDIDTDPDTGSDDTGSDYGRALLRASAFGYNAWLSAVAAGLGGSVYGRSSPEVTRIVRR
                     YTGTPARHLFTLVLGHPAEAPQESGP"
     gene            14436..16202
                     /locus_tag="B061_RS0116365"
     CDS             14436..16202
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964454.1"
                     /locus_tag="B061_RS0116365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_018512611.1"
                     /transl_table=11
                     /translation="MSDTERIQIRALGRRVLRRFAAHKAGFALSLLTVVLSTALGISGP
                     LFLRVIVDEAVPQRDRELLMWMCLGMLGVGIAQSGFFYLQSRLTNSIGLGVVHDLRVDV
                     YERVQSMPITFHAGRSGAEVQTRLASDIGGISDVITFTAQRALGSLTMVITIGTAMFIL
                     SWPVALVAIGLTLGLVIMNQRYAERQRLLAVEAQEHTSEMMRLTGEHLSLPGVLMGRTL
                     RCWDGQRDRFRASSSAIADLTIRERSMATSAESIIGVSFAVIPPVVYWMAGGGFTSLSI
                     GTAIVLVVLQLQLAQPIQALLGLSTSVRRSLAHFDRIFEYIDLGPTAALPAPRTPHTGT
                     RVPAVGITLREVSYRYPESGRSTLRGIDLDFPAGSTTMIVGSTGSGKSTLGYLVAGLLE
                     PGAGTVRVSGGDDKPFETVLLVPQEPGIFNASFRDNLLLARPGATEAELREVLSRLALD
                     DLVSSFPEGLDTSVGERGYQLSGGERQRLGLARALLSDAPVVVLDEVTSALDWATARTV
                     QAALEELRGNRTTVVISHRLSGVKDTDQVVVLAEGIVAENGTHGELRTTPGRYSDLLRM
                     RDEDLSEAGTTP"
     gene            16199..17320
                     /locus_tag="B061_RS0116370"
     CDS             16199..17320
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377908.1"
                     /locus_tag="B061_RS0116370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_026241596.1"
                     /transl_table=11
                     /translation="MTSPIGLSAAIMTHPARRARALALRDSIPELSLQVVEDPDPYGPG
                     SCSARTAVLAWGAVAPEATHHLVLQDDAVPVADLRERVLRRVGERPAAAISLYTEWASA
                     TSSAVHLAAWLGQSFAEVCDPYTPCIGLVLPAEAARELARARPEVPQDDVMIAGVLRRL
                     GVPEYVTVPNLVQHATEVSLTGNTPMGLRLAACYSSAAHSDTAPVVDARVDLLPCFSRS
                     YGRPYYLERDPGSVSGWSQRGLLETLRRRDVDVPALQRTAARRSADLHRAHPDLRPDIV
                     ISLWITAWLAGAELRRLLGDHAVAPVEVLDRRLGQIALANIGPGIFDQYMLPERLLELS
                     PVLETFARTAFTEGVTPSGARDGRFPDHRSLSG"
     misc_feature    17334..17349
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.35"
                     /tool="antismash"
     misc_feature    17336..17350
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.32"
                     /tool="antismash"
     gene            17407..18384
                     /locus_tag="B061_RS0116375"
     CDS             17407..18384
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377907.1"
                     /locus_tag="B061_RS0116375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyl transferase"
                     /protein_id="WP_234017797.1"
                     /transl_table=11
                     /translation="MRQVNPGVQIRLASAGSGADYYRSRGVEAVDLGFDDADDMGEAAS
                     WRVWRFLYERADADLVVSDEYLTVPGFCRHVLDVPNVLITDWFFAEYGRPDADSIMDDA
                     LEVVVPDFPEAHPVPQATTAPVWFCGPLVDAFAPQRAEARKALGLDEDALIMTVAAGGR
                     PDRIAALRIQLQALEVWSRYAAPTDQLLLLADPPPTRGRAPATPNVRWLGRTDRPELYY
                     RAADVVLADALGFTGCELVANGVPVIASVTPDPGRAVRVGFAERMDMLERTGLLTRTHA
                     DEDPAALWDSVREMRGRADDPAPGHLWADPLDVATRILGHSRTT"
     gene            complement(<18614..18733)
                     /locus_tag="B061_RS40190"
                     /pseudo=""
     CDS             complement(<18614..18733)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006345543.1"
                     /locus_tag="B061_RS40190"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRSLTLNNGVPVPQLGLGVWPLTDAQAYDAVSHALTAGYR"
     misc_feature    complement(19094..19105)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            complement(19158..19367)
                     /locus_tag="B061_RS40510"
     CDS             complement(19158..19367)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="B061_RS40510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_109981454.1"
                     /sec_met_domain="p450 (E-value: 5.8e-09, bitscore: 27.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDLARDHNPHLGFGHGVHHCVGAPIARVQLQEAVSALVRRFPGL
                     RAAAPPQWKAGLKTRAPRSLPVAW"
     gene            19375..19854
                     /locus_tag="B061_RS36665"
     CDS             19375..19854
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B061_RS36665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_234017798.1"
                     /transl_table=11
                     /translation="MSKTVSSWLADELTYTALGPVRRPAVLPDWLAQELERTGHLPALD
                     VPARRAVPPRAQQDVIAAGGGRHHTHNLLASVLAPVETCGQVAQGAGFSDILNRAAYTL
                     GGLVAASRLSQQEAEDLLLQTAAAARPGQEDRAEQIIRSGMAAGLKRPLYPGSVR"
     gene            19851..21370
                     /locus_tag="B061_RS36670"
                     /pseudo=""
     CDS             19851..21370
                     /GO_function="GO:0003896 - DNA primase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158409.1"
                     /locus_tag="B061_RS36670"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="phage/plasmid primase, P4 family"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTSPGNDNMLFHFDPQLDAAQIREQGPLPLPVQALTSPAATSPGE
                     ATQHGLLPDTLTDRGNAKLFVKFYADDYRHVPGMGWYRWDTTRWQIDEDDTVVWAAGDL
                     AESIAFSDPRGRYTTQALQQHRRRALSTTGMNAMLTQAKSAPGMVLNAARLDADAYALC
                     TPDGIVDLRTGLLKTSDPNKDFHSRSTSVGPRPSPTPRWNRFLTDTFGDDAEGTEMIAF
                     LQLLLGYSVTGDVGGQVLPFLFGSGKNGKSVLLDVLMKLLGDYADAAPPGFLTARPYEG
                     HPTDSPSSTDGASSSAPRSSTETSSMRPASNC"
     misc_feature    20994..20996
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21367..21768
                     /locus_tag="B061_RS0116400"
     CDS             21367..21768
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158408.1"
                     /locus_tag="B061_RS0116400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6009 family protein"
                     /protein_id="WP_018512617.1"
                     /transl_table=11
                     /translation="MSSLITEDEISHEIELVWLEETADLDYVRQSLDRLPTRRGKPPYH
                     RDGRMIGYALLSSRAKASRSSGTFRRRVFWLLPHDRDTQPQGLYATGAPAEAVDPRTLA
                     PATKGYKTERSEGGPPSTAMGVSAMSVGR"
     gene            21845..22659
                     /locus_tag="B061_RS38385"
                     /pseudo=""
     CDS             21845..22659
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033580.1"
                     /locus_tag="B061_RS38385"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGRPVRDRRQVLNGILWKLSTGAAWRDLPERYGPWKTVYERFRRW
                     SADGTWGRLLAHVQQHSDAVGEVDWSIVCVDSTVVRAHQHAAGARKGGPGKVRHSAGPA
                     AG"
     gene            22771..22944
                     /locus_tag="B061_RS38390"
     CDS             22771..22944
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015575508.1"
                     /locus_tag="B061_RS38390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CsbD family protein"
                     /protein_id="WP_078533152.1"
                     /transl_table=11
                     /translation="MAADEKAQAKTDQAKGKIKEVAGRSVGNERLTAEGRTDQAKGDAR
                     QAKENVKDALTD"
     gene            complement(23056..23190)
                     /locus_tag="B061_RS40515"
     CDS             complement(23056..23190)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B061_RS40515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_267880928.1"
                     /transl_table=11
                     /translation="MSPDTIPMGTDLARPTTAQAVVPPSVKPWPRSDELDRCPVPPTY"
ORIGIN
        1 catgatcggt ggagcaacgg cttctaaagg ctcccgtaac tcaacgcagg cctggttggg
       61 gcttcgctga ggtgtcaggt tgtctcgttc cggacctact tgccgccttt agcgaatgct
      121 caagcaatcg gcgtacaccg ggacaccgct gaacggcgcc agcagttacg ggacagcttc
      181 tagataagcg gccggattga tcgcctcccg cgttcccgtc cgtcagagat catttacggg
      241 acagccctta gtcaccgacg tcacggcctc gcaggtcctg cagtgtctcg cgccgcacca
      301 gcaggcgtgc tgtgccctcg tgcaccgcga cgatcggggg ccggccgacg aggttgtagc
      361 ccgaagccat ggacaggtga taggcgcctg ccacgggtac ggcgagcaga tcgccggggc
      421 gtacgtcgcc gggcagcggg acgtcggagg cgaggacgtc gccggcttcg cagtgccggc
      481 ccacgaccgt ggccaccacg cgctcggctt tcggccgggc gctgatcagg tggggtgcgt
      541 agcgggctcc gtacagggcc gaccgggggt tgtcgctcat gccgccgtcg acggccacga
      601 acatcgttcc cccggtgtgc ttgacggcga gcacgcggta cagcgccacg ccggccgggc
      661 ccgcgatcgc ccgtcccggt tcgatgacga gcctgggcac gggcagccct gccgccgcgc
      721 agctcgcggc gagttcggcg cgcagtcggc gcgccaggga ggtcaggtcc aacgcggggt
      781 ctccgggccg gtaggcaatg ccgtggccgc cgcccatgtt gagttcggcg aacgtggtgc
      841 cgtggctgtt cctgatccgg gccatcagcc ccaccatccg ccgcacggcc accaggtacg
      901 gcttgacgtc cgatatctgg gagccgatgt ggcagtgcag gccggtcagt tcgagctgcg
      961 actggccgag cacgcgggcg acggcgtgct gggcggaccc gtcggtcagg gacaggccga
     1021 acttctggtc gtccgtgccg gtccggatct tctcgtgacc gccggcggag acgcccggaa
     1081 ccacccggac catgaccttc tgccgccccc tgggcccgac cagcgcggcg atccgcgcta
     1141 tctccgaagg gctgtcgacg acgatccgtc cgaccctgag ccgcagcgcg gtctcgaggt
     1201 cgcgcggaga cttcgcgttg ccgtgcagaa ccatgcgctc gggcgggaac ccggcggcgt
     1261 gggcgagttc gagttcgccg gccgagcaga cgtcgagccc cagcccctct tcctcgatcc
     1321 accggaccat ggcccgggag aggaacgcct tggccgcgta cagcacgtcg gcgtcgggga
     1381 acgccgcacg gtaggtccgg cagcgcgtcc gcacctcatc ctcgtccagg acgtacgccg
     1441 gagtgtcgaa cctgtcggcg atgtcggcga gttggacccc gcccacggtc agttgcccgt
     1501 gcggaaggcg ggtggtggag gcgggccaga ctgagaggtc gctcgggccg gcggcgaact
     1561 cggtgagagg gggagcggac atggggacat ctcctcggaa gccggggggc agcgggtggg
     1621 tcacagcgtg gcgacggtcg cgtcggcaca cagcggctcc gcggagacgg ccggcgcgga
     1681 taggaccggg tcgagcacga gccggctgat gcccagaggt gatgcgaggg aacgcagggc
     1741 ggactcggcg agcctgatgg agggctgacc ggcgccgagt gtccgggcca gcaggtcgcg
     1801 gtgggtgaag gcgaccgcgg tgcgctcgcc cagcggggtg cggaaggtgc gcagcacgaa
     1861 gcctgtcgct acccggtggg cgggcacgtg gaggagcccg gccgggtcct gttcgtcggg
     1921 gtcggggtcg tcgtacagga agaggcacat gggtttcctc cggggaagtc gcggccggcg
     1981 ctctcgccga cgcatgacgt cgaagctatg cccgtcttct cggcgaaagc cctgttacct
     2041 gacgcaacct tgatggctta cgcccagttc atacggtgtg ctgacgctca gagccttcgg
     2101 gccgcccttc aatggaggtc cggaacagga cgagtcagga gggcacccga tgcgccagag
     2161 gatcgtggtg ggcgtgagcg gatcgctggg gagcctgacg gctctgcacc aggccgcgtc
     2221 ggaggcgagg gagcgcggtg cggagttgta cgccgtactc gcctggcaac tgcccggagg
     2281 agggctcggc agtcgtacca ccctcggtgt tgagacgttc agggaatgcc gtgcggcggc
     2341 acgggaggag ttgtgcacag ccctggacct ggcgttcgcc gccaggagac cgggagtcac
     2401 cctgtccgga ttcacggtgc gcggcgagcc gggagcggtg ctcgtcgacg cggtccggtc
     2461 ggccgacgat ctcctggtcg tcggcacggg actacgaggc cgatggcttt ccgggctacg
     2521 ggcaccggtg gctcggtact gcctgacaca cgcgccgtgc cccgtactcg ccgtccctcc
     2581 gaacccgctc gaagccgaac tcgccgaggt acgccgtacg gggtggcacc tgccgttcat
     2641 ggagcgggag ccggaacggt gagcgctgca cggttgcttg cctacgccga gaaccggggg
     2701 tgggccgacc tcaccggtgg cgtccattgt tcgccggtgc accgcgtcca ccgcgtcgct
     2761 caccacccag accccgctgg tacccgcccg tgcacgtgat ttgggtgcca cgtagggccg
     2821 aacgcgagcg catcacggcc gggccaccgc agctctgtgt ggccgatcca gccgtgctcg
     2881 tcctgcgaag caactgcctg ctcaactccg gacgcccgac cggaaagccc agcgccgcct
     2941 tcgtgtcgtg gcggaggacc gggcggatgg aggctaggca ggcatcgggt gagataccgg
     3001 tcgtcgtagg cagggcgggc gccacgtccg agggcccagg aaccgccggc ctggcggtgc
     3061 tgtcgggggg caggatccgg cagaacctgg ccgaatcgga gggcatgaga gcctggagcc
     3121 atgaaagcga accgcgggct gctgggcgat gagcgacgcg atcgcggcct cgaactgcca
     3181 cctacccgcg gtgtcctgat cgccggcggt ctggtgcgtg tgtcgggcgg ggccgccgcg
     3241 ggctgcgggg cgctgttcgg cctgcttccc gtcctcgcgc tgatcggcag attcggcttg
     3301 cccgacgacc caccggcctt cgtgccggtg ttcggaggta ctctcctcgc tgcgagcttc
     3361 ggtatcacca ttttcctgat ggtgttcggt tacgccctga ccttccacca actcgcgctc
     3421 gcggacatgt acgccgcggc cgcggacgct ccctcgctga ggaacgcggt cgaggtccgt
     3481 ggccccgtca gccgcacgcc gttcttcccg gcggtcgtga ccagcgtcgt catcggctcc
     3541 cttctcctcg ccacggccgg catcctgctc gccgcgtccg cctggccggc gatcgcgagg
     3601 actttgctcg tcctgggcgt gctgtgcgtt ccattggtcc tcgccctgat cgccgcaggg
     3661 cggcggtggg cccgctcggc gggcgagcgc cttcccgcgc aggccctcgg tgaacagggg
     3721 cccgcgcggc tcctcatcgg cgacgtggac acgaagctgc ggcaacaggt caaggcccgc
     3781 aaccgcgccg aggccacccg cctcgaccgg acgaatatcc cggtgctcgc gaccttcgtc
     3841 atcgccgtgc tcgccatgat gaccccttcc ctctcgccca ccaccgtcct ttggaagcag
     3901 gtgcagctgg gtggcgccgg actcgctgcg ctgtggctgt tcctcgtccc ctgcatcgcg
     3961 gtcctccggg cgtggcaact gcgacgcacc ctcgcgcggg tacgccgcgg cggcgtggat
     4021 gtgaccgctg tcgaccgcgc gcacgccatc accgcgacca cgactcaggc agcggagctg
     4081 cacgcggccg cggcggtctg gacgctgctc ggcgcggggg cactcggcac catggtcccc
     4141 aggaccgctg ctgtagcgcc ggtgatcatc gtcgcgggca gctgggcgtt cggcctggcc
     4201 gcgctcctcg ttctgtcgat gcgctcggac gcggccgccc cgaagctccg ggaggaattc
     4261 ggctaccgac tcccgagcca gacctccgga aacgacaaca cctggcactg agctgccgac
     4321 ggccggcagg ccctcgcaaa gatccgtgcc aaagcagccg cctgcagcga taccggccgc
     4381 gcgagccgca ccgaccagga ccggcgcccg gccctctcat cccgccctct attggctcag
     4441 ctgcgtcttc cgttcggaga acgcctgaag acggcgtctg ggacaggcgg tgaaccgtag
     4501 acgggtcgcc cgtctcatgc gcgagcacgg catccagggc gtgacccgcc gcaagcggcg
     4561 ttcgctgaca cgagcggaca agaaggccag gccgcccccg gacctgatcg gccgcgagct
     4621 ccccgccgaa atgcccggca cgaaactggt cggcgacatc accgccctgc ccaccggcga
     4681 gggctggctc tacctcgcct gctggctcga cctggccacc cgcgaggtcg tcggctactc
     4741 gatggccgat caccaccgcg ccgattttgt cacatggccc acggccgcgg tggactgcaa
     4801 cccggctgag tgatccacag cgaccgcggc agcgaataca cctcgacccg attccaggac
     4861 cgaagccggg agttggaact ccgccagagc tgcggacgca ccgggtcctg cttcgacaac
     4921 gccgccgcgg agagtttctg ggccctgctc aaagaagata tcggcacccg cgtctggcct
     4981 gaccgggcca ccgcccgtgc cgacgtcttc gatttcatcg agacgttcta caaccggcgc
     5041 cgacagcgca gacacaaggt cttcggctac ctcaccccga ccgagacccg ccaacggcac
     5101 accctcgcgg cataaccatc gagtgtccag gatcacgggg aagcttcacg atgacagtcc
     5161 tcagcctcgc cgtcgtgcga cgggcacggc gtaaaagaac cccgtcgaag gccgtcgagc
     5221 ggagctgacc aacggaaggg cgggtcggtg ttcatgtgcc gggacgtcgc tcagtcgcag
     5281 gtgacttcgt cgcgcggatc gtatcgcgtc tcgaagttct ccgtcctgac cgttctgcca
     5341 ccgtccttga aaagccggtc gacggagacg ttgaagcctt cgagcggggt ctgcgggacg
     5401 cagctctctc cggatgctcc ctcgcgggtc gtcggctgct tcacggaggt gcgcgggccc
     5461 ttgaccgatt cgatctcgtc atacctcttg gtgccgagga aggtaatggt gaccgaggtg
     5521 ttcgtagcac gggcgtcgat gtatatcgtg ttgccggagt cgttcctgaa cttcaggtcg
     5581 agactgcccc aggccaccgt cgcctccctg ccctccggat agcgctcgat gtagaaggag
     5641 tgtgctccgt actccaccgg tttcacaccg gcgaagaaaa gggcgttgaa aaccgtggtg
     5701 gccactgccg agacacctcc tccggcagcc ttctcgtacc ggtcgttgtt gatgatgacg
     5761 ccctccacga agccgttggc ctcggtccgc tcacccaccg tgcgattgaa gctccagatc
     5821 ccgtcaggct ggacaaccga gccgttgatc agctctgcgg cccggccgat gttggtgacg
     5881 cggtaggcat cgggctcgaa atcgaccgtg aaggtcgaca tctgctccgt gatgccaagg
     5941 cggcccaggt tgtcacgggt cagcgtgggc tcgacctcct tgactccgac cgcgcccgtt
     6001 cgggctgctc cactcttggt cagcagcggc agtacggcct tcttgagccc cacggccgtg
     6061 acatcctgcc cggtcctacc gtcggaggcc accgccactc ggccaccgtg cacactcagt
     6121 tcggcattgg ccggctcgtc cagggcaagc gcgagcgcac tcgctaccga cggttcgacc
     6181 aggagtccct cgccgtccag taccggggcc aggggcttgt ccccgtcggg cttcatggca
     6241 aggtgcttgc cgagcgccgc cgggcctatc tcgatttttc gaccgttgac ggtgagcgtc
     6301 accggcgccg acatcgccgg aatggcgaac tcctccatcg cgcgctcgac ttccgccgca
     6361 ccgacctgcg gttcggtcgt gcgaaccgga agtcgcacgg gccctgcccc ctggcccgga
     6421 atctcctcag caagcctctc gaccgcgccg tccacgtcca gggaccgccc ggtgaccggt
     6481 cgcaccagca ccggctcgcc caccttgaac ctgacggcgc cctcccgcgc cttccggtcg
     6541 tacgacttcg ccttttcggc cagcgacgcc cgggccttca ccgcgtccac acggatcacc
     6601 ggctcgacct cgcggtcacc gttcgcgaag aggcggccga tcacggtgaa cggatcggct
     6661 cccggctgcg cggcccgggc gacggtctcc tccgtgtcca gcgagatgcc ggatacgcgg
     6721 acggtgccat cactgtcacc gaggcgcacc ttcaccggct ccgaccaggt cttgcccagg
     6781 ccgctgtcca gcctctcccg cgcctgcgcg gtactcagcc ccccgatgtc cacgccgctc
     6841 acccgggcac cggcgggaac ggtgtcgtcg gcgacgaaca gccccaccag atacagccca
     6901 ccgaagcccg cacccacgac tcccacgacg agcgcgaccc ggcggcctat tcggcgacac
     6961 ccggccgacg caatgtcggc aggtcggcca agaaaagatg ggcgactcac ggatcctcct
     7021 ccgtctgtga ctgcggcgcg ctgcgggcag cacccgcaca gaggcccctt gccgagcaac
     7081 aatgaagaaa tgctttaacg caaccggttt gacacacacc ctatcctgct aggtaactaa
     7141 gtagattagt tgcgtacggt aactggctct gtcgcccaga tcaggagtga tgcgagagtg
     7201 acggctgctt tgtatgacgc ggcggtcttg gcgtagcggg tggcgatgcc ccgccattgc
     7261 ttcaggcggt tgaagcaccg ttctacgacg ttgcggtgct tgtaggtctc ccggtcgaag
     7321 gctggcaggc ggcctccgcg gctgcctcga agcgcccggt tgtcggcctg gtcagcacgc
     7381 tcgggaatcg tgtgggcgat ggttcggcgc cgcggccagg tgcggatcgc cttcgagctg
     7441 cagcccttgt cacccaggac gtgaccgggc cgaactcagg gccgccccgg tccgatccgg
     7501 gcacccggga tcgcttccat gacggcgatg aaccgggtgt agtcgtttgt gctgccgccc
     7561 gtgacgacga atgcgagcgg acggcgccgc ccgtcacagg tcagatggat tttgctggtc
     7621 agaccgcctc gggaccagcc cagggccggg tcgcagagcc cccttttcga gccccggccg
     7681 catgctggtg aacccggacg acgggtcgag tcgaccgaca ccagccacgc gacgtcgccc
     7741 gccgcgtccg ccttcgcctg agcggcccgc agcatccggt ggaacgttcc gtccgcagcc
     7801 cacctgcgga aacgcgtgtg cagagtggcc cacggaccat agcgcttggg cacgcccctc
     7861 caggccgtcc cctacaccag ccacgccaac gcctacgtga ccaagcccgt caacctggac
     7921 gccttcgaac aggcggtcca gagcatcgac gcctctacct cgacgccgcc acgcgaccgc
     7981 acccgtaagc ccgccgactg ccgcgaagtg cggaagacga cgatcgcggc gtgacgtcgt
     8041 tgcacggcga gcagcatgag atcgtccaac gcctcggccc gcgagcctga gttgtcggcc
     8101 atgagctgat cgaagtcagt catcgtgtcc gcatgttgac gcgagcctct tacggctttt
     8161 gaagtcgcag gctcggctct ccggtgtgcg ggcacgagcc ggtcgcaccg gttggaggga
     8221 tggacatgcg gcgcagcaga tcacgtgtcg cgcggagctt cagggtgctg cgccatctca
     8281 cgcccgggtg acgggagcgt agatgcgaca gggcgcgggt ccccagatcg gtgctacgga
     8341 agcgctcttc cagagttacg tcggtgatga caccttgttc gcagtggtca cagagtcgat
     8401 agcggacttg gccgacgacc ttgcggatgt ggaccaggag gaggcattcc tcggcgggac
     8461 gggtgccgcc ggggacgcgg gagggcagga actcgatcga tcggtagacg aggagccgac
     8521 gccgcaagcg gtccaggggt cggccacggc gagagtgccg ggggccgtcc tggcccttcg
     8581 ccatttcctg aactggagag atcgggccga acagagtgct cgtaggacgc gcatgttgtt
     8641 cgtgcatgcg agcccgtata ccccgagacg cgtcacaaat gtccttcttg tagtggatcc
     8701 cggtacggcg ccccgaacgc cttccactcg cgcctcttac cgtggcgggc agcgggtgtc
     8761 ggttactacg cccttccgct ccgggcggtc gggcgcgtgg acacgtggtc cggctgtcgg
     8821 cctcgggcga gggcgagcgg gcagaccagt gcggcgagtg ctgcggcgag cgtatcgagg
     8881 attcctccgg cgtgcagtgc ggtggccaac gtggtggtgg ccttggggtt gatcacgtgc
     8941 gccgctgcca gcagacccgt gaagatgatc ccgagggcca cggcgggcac ggcgttgcgt
     9001 agcagcatgc ccagagccag caggaggcag aggtccgtcg tgccggcgga gagcgccacg
     9061 ccggtcgtgg agaggtcggc ggggtggagc gggaagtgcg cggcgccgcc ccctcccgct
     9121 cgacccactg cgcgagtgcc gccagcccgc tccagcttgg gccgggtcgg ctcctcggcg
     9181 aacttcccgt acgcctcggc cagctcatca gtcagaatcc accggcacga acggaccgca
     9241 gccatcccca gcacccgcca ggcgctcttt gcgtgagcgc cggaggagcc accagcctgt
     9301 gtgctggttg accatgatcg ttctcagcgc aaacccctgt accgatgttc cccgagaccg
     9361 gagtcgacgt gaaccctggc acgctccgtg gttcgtctcg ttttcgagcc gctcggcacc
     9421 cgctctcgtc ccccatctgg gcaaacagtt gcgatgtccc gaggtgatca tctgatggtc
     9481 cgtcaggatt attcgacggc gcgggtgttg aggcgccagc cgtttgtcac ctcaattttc
     9541 cttcacgttt tcttgagctt gaaaagtgat cagcgaccct aggttgagcc tgactccggc
     9601 gcgcagatcg gccgaatctc gcgcgggaga tgacgtgtat tcgcgagaga agggaagagc
     9661 agatgcttga taccgatccc acgccaggag gagcggtcga cctcgtcgtc ggcgatgccg
     9721 atgagtcctg ggaggacctc gtacgcgatc tgatcgcggg cccggcggac ccctcgcgca
     9781 tcctcacgga ctgcggtggt aacggctgta actgtgccgg ctgtgtcggc tgcggcctga
     9841 actgcatgag cggcggctgg aagtgcgcca cgtgtggcag cgcgtgctgc tagtgccgtc
     9901 cccggccgac cccgccggtc gaggcggtag gtagcgaatc ggcccgccgg cggtggtacc
     9961 cgtcggcggg tgccacccgg acaaggagcc acggtgttcc ttgcctgacc tgaatgacgt
    10021 gaacatgaaa cagcttgatc cgcttctctc gcgctacggc gtcgtcgggg acgccttcga
    10081 cctctccccg tcccgctatc gaggtctgcc ggagctgagc tcctacgggg tcgatctcgg
    10141 cagcggcttc ccgggcttgg aggcacgccc ggacgaccgg gttgtggccg gagggcatgc
    10201 gctgggagac aaggacaggg cacgcctgct cgccatcgcc gagggatgcg agcgctactc
    10261 gggggcgcag ttcgggacgg agggcgtagt gaccgccgcc gcgcacgatc tcgatggcag
    10321 ggtgctcgac tggtcgcggg ttccgcgtct gtccgacgcg gagtacgcgc acccgcggtg
    10381 cccgctcgtc cccttcgatc cggccgcgcc gatcaggtgg gtgcgggggg tggatctccg
    10441 ggacggagac cccacctggc tgccgctctc catggcggcc taccggtcgg ggcgccgtct
    10501 cccggccgag cgcttcgtgg cgagcatctc gacgggctgc gccgtgcaca ccgatcccgc
    10561 gagtgctgtc ttcggcggcc tgagcgaggt cgtcgagcgg gacatgatcg ccgttctgtg
    10621 gctacagaag ctgccgctgc cgcacattcc tttcgacgtg ctggacgagc gggaactcac
    10681 cgtggtcgag tgggcgcacg atcgcttcct cgacaccgtg ctgctggatg ccaccagtga
    10741 catcggtgta cccacggtgt actgcatgca gaccgcaccg catgaccaga cgatacgcac
    10801 catggtcggg tgcggtaccg ggctcaccat tcaggatgcc gcgtacaagg cgttgctgga
    10861 agtcacctgc ttccgtgatt cgctgcatgt ggagtgggag gagcccgagt ccttcgccga
    10921 ctacaccgat atctcggacg gcgcgaagta catgggcaag ccggagaacg ccccgcactt
    10981 cgcattcctc accgatgacc accccgaccg gccctcgttc caggatcgcg gccgttacgc
    11041 cgccgatgcc actgaggggc tgacccgcgc tgtccggagg ttcgccgagc tggacatggc
    11101 ggtgatcgcc gtggaccgga cgacgacgga actcgcctcg gtcggactgc actctgcgac
    11161 cgtggtcatc ccggaccttc agcccatgtc cctcgtgccg ctcgcccagt atcacgcaca
    11221 tcaccggctc tactccgccc ccgcggcgat gggatatcgc gtactgcctg tcgaggagtt
    11281 gaacccgtgt ccgcagccgt tcgcctgacc cgtctgtccg tcctcggtac cggggctttc
    11341 ggcgcccggg cgtccgaact gctgccggag atctcgggcc tggccgtcac ccaggtcggt
    11401 ccggagatca cctgcgacat gctcgtcgat gccgatgcag ccgtgctggt actggaccgt
    11461 ccagcccggc ggttggcacg ccgattccgg caggtggcct ccgaggcggg aaagccgtgg
    11521 ctcctggtgg agttcgatca ccccgtcatc cgagtgggac cgtacttcga tcctgcggcc
    11581 ggcccatgcc tggactgctt ctacgcgcgt gaggaccagc acgccgacaa gccggctccc
    11641 ctccggaaac ccgtacccgg gcacgagcac acgcacgaac acaaccacgg acacgcccac
    11701 gcaccggact gttcgcacgc atcggccccc gcgtcggcgg aggaaggact cggcgtcgag
    11761 gcggcggccg gggtcctgcc gcatcaggcg cgcatcgccg cggggctgct gagcctgtcg
    11821 ctggccgagc aggttcgcgg gcgggtggtc accgtcgatc tccgcacggc ggcggtccgc
    11881 tcggaccagg tgatcggctg ccacggctgc ccgcactgcg gcgacgagac ccaacgcacg
    11941 ctcatgtcgc gacagctcga tcacctgttc cgtaccgtgg gaggcgtcac tcatgacgag
    12001 caccgatagt ttccccccag gcggcctccg gccccggttg cgcggtgggg tggcggtctc
    12061 cgccgccgac ggccaggtcg tcttctccgc cggacagatc cgcaagagga tcggcggtgg
    12121 ggacgccctc cggctcctgc tgccgatcgc gtcggcgatg gacggacgcc gtacggtcgg
    12181 cgacctcgcc gaagcgacgg accttccgta cgaggcggtg gcccaggccg tggcactgct
    12241 ggtgaagcag ggcctcgtcc tctccgggga ggtctcatcg ccgaagccgc tggcggcagg
    12301 ggtcgtcgac tacctggaac agaccgctgg ttcctcggcc acgttccgcg acgcctccga
    12361 ggtactggaa cgcctgtcgc gatgcgcggt gctgatcgtc gccccaccgg ggcacacgga
    12421 agccgtccgc gccgacctgg cgaggagcgg cgtcggaaca gtccacagcg cgtccacgcc
    12481 ggccggagtc ggcaatgagg tgctcgacag cctgcgggaa gcggcgggca gcctcgtggt
    12541 gctgtacggc ccgccccgcc acgatgacgg cacggacagc ttcaccgacg actgcgcggc
    12601 ccgcgacatc gcggtactgc actacgcggc gcaccagggg caggtcgacc tcggtccgct
    12661 ggtgcatccg cgggcgacgc tgtgccgacg ctgcttcacc agcggctacc tcgcggagtt
    12721 cggaagcgaa cagccggccc cggccgacac cgccacgggg acggtcgccg ccggactcgt
    12781 ggtgggcgaa gcgctggcct acctggccga cgtcgacagc atgcgcacca gtcaggctct
    12841 cgtccgctgg accctgccgg actccaccgc ggtgcggtac gcggtctcag ccgaggccga
    12901 ctgcgcatcg tgcgcgacga cgtcccgccg ctcgggagag cgtgcaaccg tactggaagc
    12961 gtacgaggac gtcgtcgccg cgcaaccgct cgccgaccgg cctcagcctc cggtcaccgc
    13021 cggccgggag aagcgcctga cggcgctggg caaggaacgc gagtcgttcc ccaccgcacc
    13081 ggtgatacca ctgcctccgc caccggcgac cgcgtccgcc gccccgaccg gtgacgaggt
    13141 gccggccgtg tccgaagcgg gcccgtccgg gacggtgggg accgccgacg cggcattcgt
    13201 cgccgacctg gcggcgatgg tggcgggacg gcgcggggac ggcggacctc gcaggtggac
    13261 cgcgtccggg ggaggcctcg cgtcggtcga gctgtatctg atgtgcgcgg acacggtctc
    13321 cgggctgccc gcgcacaccc tcctgaagta cgacgacatc gcccaccggc tcctcgtcac
    13381 ccgccggacc cacggccccg gcctatggag gtccatgctc gacgcgaccg ggctcacgga
    13441 gactccggac gtcgttctgg tcgtcgtcgg cgcgctctgg agactgaagc tcaagtacag
    13501 caccttcggg atccggctgg ggcacctcga cgccgggtgc gccctcgcgc aactgcacgc
    13561 ggtggccacc gacagaggag cacgcgtcac tctgaacgac cgctggcagc cgacgctgcc
    13621 gacgttgctg gaactcaagg aagacgaaca ggtcatggcc gtggccggcc tgtggacccc
    13681 gcggagcgcg cgatgcccct gatcaatgag accgacctgt ggtcgctggc gaagcgtgcc
    13741 ctcgcccccg ccgaccgccc cgacgagcgc acccctccgg gcgggccgtc ggcccaggac
    13801 acctcccgga cctccccggc ctcccggatc tctcggagcg tgccgctcca cgatgtgctg
    13861 acagcccgtc gatcggtccg ccggttccgg caggacccgg tgcccgacac cgacctcgcc
    13921 acccttctgg atctggccac gtcgaccgac cggcagatgt ggccgcacgg tacggccgcg
    13981 accaccccgc aggcatggct cgtcagcggc gtgacaggta cctcgggagc gcggctgcgc
    14041 cagtacatct cgcggcggtc cacggcggga cagaccacgg cgggggagtt caccgaccgc
    14101 ggcgacagcc ccgaaccggc cctgctcgcc acgcgttacg ccccggcccc ggtaacgatc
    14161 ctgatctgcg cgcagatcac cgacgacatc gacaccgacc ccgacaccgg gtccgacgac
    14221 accggctcgg actacgggcg ggcgctcctg cgggcgtcgg cgttcggcta caacgcctgg
    14281 ctgtcggccg tcgcggcggg gctcggcggc agcgtgtacg gccgttcctc acccgaggtg
    14341 acccgcatcg tgcgccggta caccggtaca ccggcgaggc accttttcac cctggtgctc
    14401 gggcatcccg ccgaagcccc gcaggagtcc ggaccgtgag tgacaccgaa cggatacaga
    14461 tacgcgctct cggccggcgc gtactacggc gattcgccgc gcacaaggcc ggcttcgcgc
    14521 tgtccctgct gaccgtcgtg ctgtccacgg cgctcgggat cagcggaccg ctgttcctcc
    14581 gcgtcatcgt cgacgaggcg gtgccccagc gcgaccggga gctgctgatg tggatgtgcc
    14641 tgggcatgct cggcgtgggg atcgcccaga gcggcttctt ctacctgcag agccggttga
    14701 cgaactcgat cggactcggg gtggtccacg acctgcgggt ggatgtgtac gagcgggtgc
    14761 agtcgatgcc gatcaccttc cacgccggcc ggtcgggggc agaggtgcag acacggctgg
    14821 ccagcgacat cggcggcatc tccgacgtga tcaccttcac cgcccagcgc gcgctcgggt
    14881 cactgaccat ggtgatcacc atcgggaccg ccatgttcat cctcagctgg cccgtcgccc
    14941 tggtggcgat cggtctcaca ctggggctgg tcatcatgaa ccagcgctac gccgaacggc
    15001 aacggctcct ggctgtcgag gcacaggagc acacatcgga gatgatgcgc ctgaccggcg
    15061 agcacctctc cctgcccggt gtcctcatgg gacgtacgct gcgctgctgg gacggccagc
    15121 gggaccggtt ccgggcgtcg tcgtcggcca tcgccgacct gacgatccgt gagcgttcca
    15181 tggcgaccag cgcggagtcg atcatcggcg tctccttcgc ggtgatcccg ccggtggtct
    15241 actggatggc gggcggcggc ttcaccagcc tgtcgatcgg caccgcgatc gtgctggtcg
    15301 tgctgcaact ccagctcgcg cagccgatcc aggccctgct cggcctgagc acgtccgtgc
    15361 ggcggtcact ggcgcacttc gaccggatct tcgagtacat cgacctcgga ccgacggcgg
    15421 ccctgcccgc gccgcggacc ccgcacaccg ggacccgggt acccgcggtc ggcatcacgc
    15481 tgcgcgaggt ctcctaccgc tatccggaga gcggcaggag cacactgcgc gggatcgacc
    15541 tggacttccc cgccggttcc accaccatga tcgtgggttc gaccggctcc ggaaagagca
    15601 ccctgggcta cctcgtagcg ggactgctgg agcccggcgc cggtacggtc cgggtgtccg
    15661 gcggcgatga caagccgttc gagaccgtcc tgctggtacc ccaggagccc gggatcttca
    15721 acgcctcctt ccgggacaac ctcctcctcg cccgccctgg tgccaccgag gccgaactgc
    15781 gtgaggtgct gtcccgactg gctctcgacg atctcgtctc ctccttcccc gaggggctgg
    15841 acacctcggt cggcgaaagg ggctaccagc tctccggcgg cgaacgccag cggctcgggc
    15901 tggcccgcgc actgctgtcg gacgcccccg tcgtcgtgct cgacgaggtg acgagcgctc
    15961 tggactgggc gaccgcacga acggtgcagg cagcactgga ggaactgcgg ggcaaccgga
    16021 ccacggtcgt catcagccac cggctgtccg gagtcaagga caccgaccag gtggtggttc
    16081 tcgcggaagg gatcgtcgcg gagaacggca ctcatggcga actccgtacc acgcccggcc
    16141 ggtactccga cctgctgcgc atgcgcgacg aggacctgtc cgaggcgggt acgacgccat
    16201 gacttccccc atcggactct ccgcggcgat catgacccac cccgcccgca gggcgagagc
    16261 cctcgcactc agggacagca ttccggagtt gagcctccag gtcgtcgagg atcccgaccc
    16321 ctacggcccc ggctcctgtt cggcgaggac cgcggtgctc gcatgggggg cagtggcccc
    16381 cgaggccacc caccacctgg tccttcagga cgatgccgtc cccgtcgcgg acctgcggga
    16441 acgtgtactg cgtagggtcg gtgagcggcc ggccgccgcg atcagcctct acacggaatg
    16501 ggcttcggcc acgtcgtccg ccgtccacct cgcggcctgg ctcggacagt ccttcgccga
    16561 ggtgtgcgac ccgtacacgc cctgtatcgg actcgttctg ccggcggagg cggcccgtga
    16621 actggcgagg gcgagaccgg aggttccgca ggacgacgtc atgatcgccg gcgtgctgcg
    16681 ccggctcggg gtccccgaat acgtgaccgt tcccaatctg gtccagcacg cgaccgaggt
    16741 aagtctcacc ggaaataccc cgatggggtt gcggctggcc gcctgctact ccagcgcagc
    16801 ccacagcgac accgcgccgg tggtggacgc ccgggtggac ctgctgccct gcttctcacg
    16861 ctcgtacgga aggccgtact acctggaacg ggaccccggc agcgtctcgg gctggtcgca
    16921 gcgcggtctc ctcgagacgc tgcggcggcg agacgtggat gtacccgcac tgcaacgcac
    16981 ggcggcacgc cggtcggcgg acctgcaccg cgcccatcct gatctgcggc ccgacatcgt
    17041 catcagcctg tggatcaccg catggctggc gggcgccgaa ctccgccggc tcctcggcga
    17101 ccatgccgtg gccccggtcg aggtgctcga ccggagactg gggcagatcg ctctggccaa
    17161 catcggcccc gggatcttcg accagtacat gctgccggaa cgactcctgg aactgtcacc
    17221 cgtcctggag accttcgccc gcacggcgtt caccgagggc gtcacgccgt ccggtgcccg
    17281 tgacgggcga ttccccgacc accggtcgct cagcggctga agaggaactt atcgatgaga
    17341 gtcaatttcg tctcacgcgg tcacggctac ggccacgctg cccgagacct gaggatcatg
    17401 accgcgatgc gccaggtgaa ccccggggta cagatcaggc tggcttcggc ggggagcgga
    17461 gcggactact accgctcccg cggtgtcgag gccgtcgacc tcggtttcga cgacgccgac
    17521 gacatgggtg aggcggcgag ttggcgcgtc tggcgattcc tgtacgagcg tgccgacgcc
    17581 gacctggtgg tgagcgacga gtacctgacc gtacccggct tctgccgcca tgtcctcgac
    17641 gttccgaacg tgctgatcac ggactggttc ttcgccgagt acggccggcc cgacgccgac
    17701 tcgatcatgg acgacgcgct ggaggtggtg gtcccggact ttcccgaggc acatccggtc
    17761 ccacaggcca cgaccgcacc ggtgtggttc tgcggacccc ttgtggatgc cttcgcacca
    17821 cagcgggccg aggctcgcaa ggccctcggc ctcgacgagg acgcgctcat catgacggtg
    17881 gcggcgggcg gtcgcccgga ccgtatcgcc gccctgcgca tccagttgca ggcgctcgag
    17941 gtgtggagca gatacgccgc cccgacggat cagctcctcc tcttggcgga cccgcccccc
    18001 acgcgtgggc gtgcccccgc cacccccaac gtccgatggc tcgggcggac cgatcggccg
    18061 gagctgtact accgggccgc cgatgtcgta ctggccgacg cgctgggctt caccggctgc
    18121 gagctcgtcg ccaacggcgt gccggtcatc gcctccgtca cgccggaccc cggccgggcg
    18181 gtgcgcgtcg gattcgccga gcgcatggac atgctggagc ggaccggtct actgacccgc
    18241 acccacgctg acgaggaccc cgcggcgctc tgggacagcg tgcgggagat gcgcggccgg
    18301 gccgacgatc cggcgcccgg gcatctctgg gctgacccct tggatgtcgc cacccggata
    18361 ctcggccaca gccgtacgac ttgaggccac cttcccggga tctccccgta cgagccggac
    18421 tccgtgtgca cgagtgcatg cacgggctct ttcctcgtac gggaagaccg gtcgcggccc
    18481 gcccgcggga ccgccgggcc gtcccggtga acccgtgcgc accgcgacag gtccgccact
    18541 gccgagatca ccgcgcagcg gagagggtgc gggtgaccgc tccgttcgag cacggaggct
    18601 tcatggtttg cccccggtag ccagccgtca gggcgtgcga gacggcgtcg tacgcctgcg
    18661 cgtccgtgag aggccagacc ccgaggccga gctggggaac ggggactccg ttgttgaggg
    18721 tcagactgcg catgggcgaa cgttccaggt gcggctattt cggcttgctg cgggcccggg
    18781 cagccgtagg cgggctcgac gacgcgtccg cactccggcc gggaaggtgc ccggacgtgc
    18841 ggaccgtggg cggagatcgc acgtctcgtc aggggccggg tgacgccggg ggtggtgcgg
    18901 gcggtcttga ggtgaggaag ccgatcgcct ccaccgggca cagggcgacc gcgtcgtcgg
    18961 cggactcgtc cacaaccggg gcgtcggacc tcgcgcggga gcggtggccc tcggcggcgg
    19021 actcgaagtg ccgcggcgcg gtggcgaggc agatgccgga gccgatgcag agggccgggt
    19081 cgacgacgag ccgtaaagcg gtttccgggc cctccgcgtg agtcgcacgg ggcttgtcat
    19141 cagaaggcac gtccggctca ccaggccacg ggcaggctgc ggggggccct ggtcttgagg
    19201 ccggccttcc actggggtgg tgccgcggca cgcagtccgg ggaaccggcg tacgagagcg
    19261 gagaccgcct cctggagctg gacgcgcgcg atcggggccc cgacgcaatg atggacaccg
    19321 tgtccgaacc ccaggtgcgg attgtggtct cgcgcgaggt cgagaatgtc cggggtgtcg
    19381 aagacggtct cgtcatggtt ggccgacgag ttgacctaca cagcgctcgg cccggtgcgc
    19441 cgtccggccg tcctccccga ctggctggcc caggaactcg aacgcaccgg ccacctgccg
    19501 gccttggacg tccccgcccg ccgcgccgtg cccccacgcg cgcagcagga cgtcatcgct
    19561 gcgggcggcg gccgccatca cacccacaac cttctcgcct ccgtgctcgc cccggtcgag
    19621 acatgcggcc aagtcgccca aggagccggg ttctccgaca tcctcaaccg cgccgcctac
    19681 accctcgggg ggctcgtcgc cgcaagccgc ctctcccagc aggaagccga ggaccttctc
    19741 ctgcagaccg cggcagccgc ccgccccgga caggaggacc gggccgaaca gattatccgc
    19801 agcggcatgg ccgccgggct caagcgcccc ctgtaccccg ggagcgtccg atgacatcac
    19861 cgggcaacga caacatgctc ttccacttcg accctcaact cgacgccgca cagatccgtg
    19921 aacaaggccc cctgccgctg ccagtccagg ccctgacctc acccgcagcc accagcccag
    19981 gggaagccac ccagcacggc ctgctgcctg acaccctcac cgaccggggc aacgccaaac
    20041 tgttcgtcaa gttctacgcc gacgactatc ggcacgtccc cggcatgggc tggtacaggt
    20101 gggacaccac ccgttggcag atcgacgagg acgacaccgt cgtctgggcc gcaggcgacc
    20161 tcgccgaaag tatcgccttc agcgaccccc gcggccgcta caccacccag gcactccagc
    20221 agcaccgccg ccgcgccctg tccaccaccg gtatgaacgc catgctcacc caggcaaaat
    20281 cagcccctgg catggttctc aacgccgcac ggctcgacgc cgacgcctac gccctgtgca
    20341 cccctgacgg catcgtcgac ctgcgcaccg gcctgctgaa gacctcggat ccgaacaagg
    20401 acttccactc ccgctccacc tctgtcggac cccgccccag ccccaccccc cgatggaacc
    20461 gcttcctcac cgacaccttc ggcgacgacg ccgaaggcac cgagatgatc gcgttcctcc
    20521 aactcctcct cggctactcc gtcaccggcg acgtcggagg gcaagtcttg cccttccttt
    20581 tcggctctgg gaagaacggc aagtccgtcc tcctcgacgt cctcatgaaa ctcctcggcg
    20641 actacgcgga cgctgccccg cccggcttcc tcacggcacg cccctacgag gggcacccca
    20701 ccgactcgcc gagctccacg gacggcgcgt catcgtctgc tccgaggtca agcacggaga
    20761 caagttcgat gaggcccgcg tcaaactgct gaccggcgga gaccgaatca aggctcgtcg
    20821 gatgcgccag gatttcttga gcttccagcc cacccacaag ctctggctcc tgggcaacca
    20881 ccgccccgag gtcggcaccg gcgggtccgc gttctggcgc cgcatgcgcc tgatcccctt
    20941 cacccgcgtc gtctccgacg accgcaagat cgacaacctc gctgacatcc tcgttaccga
    21001 agaaggcccc ggcatcctcg gctggctcat cgacggcgcc cgccgctacc tcgccggcga
    21061 caaagacctc accggacccg aacgcctccg catcgccacc accgcctatg ccgaaaccga
    21121 agaccacacc ggccgcttct tcgaagagtc ctgcaccctc ggcccagaac tacgcgccga
    21181 gcagaccggc ctctatgccg cctaccgcac ctggtgccgg gaagaaggcg cacccgccat
    21241 gacctcacgc gcccgcgccc gcgaacttgt cggcttggcc tctccgaagg aaatgatcct
    21301 ctccaaccag cgcaagtact acccgggcat cggactgctc cccgagcacg agaggcaggc
    21361 gaccacatga gttccctgat caccgaggac gaaatcagcc acgagatcga actggtctgg
    21421 ctcgaggaaa ccgccgatct cgactacgtc cgccagagcc tggaccgcct cccgacccgg
    21481 cgcggcaaac ccccctacca ccgcgacggc cgcatgatcg gctacgcact cctgagctcc
    21541 cgggccaaag cctcccgctc ctcgggcacc ttccgccggc gcgtcttctg gcttctgccg
    21601 cacgaccgag acacccagcc ccaaggcctc tacgccaccg gcgccccggc cgaagcggtc
    21661 gacccccgca ccttggcgcc cgccaccaag ggctacaaga ccgaacgctc cgaaggcggc
    21721 ccgccctcca cggccatggg cgtgtccgca atgtcggtgg gtcgttagcc cgttcgtggt
    21781 gcgtcgtcat gaagtgactg atcaggcctg ggcggtgatc gggccgttgc tggctccgtc
    21841 tcggatgggg cggccggtgc gggaccggcg gcaggtcctc aacgggatcc tgtggaagct
    21901 gtccacgggg gcagcctggc gggacctgcc ggaacggtac gggccgtgga agacggtcta
    21961 cgaacggttc cgccgctggt cggcggacgg aacgtggggc cggctcctgg cccacgtcca
    22021 gcagcactcc gatgcggtcg gggaggtcga ctggtcgatc gtctgcgtcg actcgacagt
    22081 cgtgcgggcc caccagcacg cggccggggc ccgaaaaggg ggtcctggga aggtgaggca
    22141 ctcggccggt cccgcggcgg gctgagtacg aagatccacc tcgcctgtga cgggcagggc
    22201 cggcccctcg ccttcacgat caccggcggg aatgtgaacg actgcacgca gttcgagccg
    22261 gtcatggacc gcatcaccat caagcgggac ggccccggcc ggcctcgcac ccgccccgac
    22321 cgggtggccg gcgacaaggg ctactcgtcc cgcaagatcc gcgcctatct gcgaaaacgg
    22381 ggcatcgcct gcaccatccc cgaacgcgca gaccagatca aagggcgccg acgacgcggc
    22441 gagacactct gccacctcga ccgcaccgcc taccgacgcc gcaacgtcgt cgaacgctgc
    22501 ttcaacaaac tcaagcagaa caaagccctc gccacccgct acgacaaacg agcccgccac
    22561 tacaaagccc tggtcaccct cgcctgcctg cgactctggc tccccaccga cattgcggac
    22621 acgcccatgc aggaactcgg aataaccctt ccactgtgac cgcctaggcg gaccgtcccc
    22681 actcgcgagt ggagaggcac gtttgcagac ggcatcgggg gtcagacggt gggggaccgc
    22741 aacgtcgagc agatcaaagg tgtgagtggc atggctgctg atgagaaggc ccaggcgaag
    22801 accgaccagg ccaagggcaa gatcaaggaa gtcgccggcc gtagcgtcgg caacgaacga
    22861 ctcacggccg aaggccgcac cgaccaggcc aagggcgacg cccggcaggc caaggagaac
    22921 gtcaaggacg ccctcaccga ctgacacagg ccagccaact gcatcaggcc ccgcggagct
    22981 ctgctccagc ggggccgtgc tgtgtccgta tctgatgctg acggaaccgt ccaagcccag
    23041 ggcatcgaaa ggaattcagt atgtgggcgg caccgggcac cggtcgagct cgtcggagcg
    23101 gggccagggc ttcacgctcg ggggcaccac ggcctgtgcc gtcgtcggcc gcgccagatc
    23161 cgtgcccatc gggatggtgt ccgggctcat ccttggtgcc cccgccccca ggtcgctgcg
    23221 actgctccga ttctaggagc ccaaagggtc ttgggcgggc catgtcaggg gaccatcgcg
    23281 ggtattcgct ggccgacgta tacccgtaca ggctgatcct tcgcatcgcc gtatgcgcct
    23341 caggtcgcac cgggccgcga cgtcaggccg atgcggctcg gtgtcggccg cccggacgat
    23401 ggctccatgc cctcaacgat caccggtctc ccgctgtccg gcccggaagc cctcaccgta
    23461 ttcggcgcca tcatcctcgt actgacccgc tggcttcccg accgcttccg cggcccggcc
    23521 acgctcgccg ccggcgccct gctcatgggg tcggtgaccg tcctcgtcgc cggggggctg
    23581 cgatggcaga tggttccggt ggtagccgcg gcggccgtcg cggcgccgtt cgcgctcgta
    23641 cccatggtcc ggcggcgcac cggacgcact ccgtggcgtg cccggtggtg gctggctctg
    23701 ccggggtccg cggcgtgcgc cgccctgatc gcatcgggcc cggtctccgc gtgggccctg
    23761 cccgtacccg agttccccga gccctcaggg cgcttcccgg tcggcaccca ggtcctggag
    23821 ttctccacga gccccgaagg agacggccgg gacgagggga ggcgcacgct ggtgacgcag
    23881 ctctggtatc cggccgggcg gagcgccccg gacgcgtcgc ggatgccgta cctcgggcgt
    23941 accgaggccg agtcgcgcac ggtgtcctcg gcgctggccg gctacacggg ggtccccggc
    24001 ttcctgctcg acggtctgcc gcgcgcccgg agccacgcgg tgcccggcgc gcccgccgcc
    24061 cgggagggcg gacgcctccc ggtggtgctg ttctcccccg gactgggagg agtgcgaacg
    24121 cagaacaccg cctgggcgga ggaactggcc agccacggct atgtggtggc cgctgtcgac
    24181 cacccttacg actccgctgc cgtggtcctc gcggacggcc ggactctgcg tacgagggtc
    24241 tcggcgaccg gcgaccggga gcaggacgct gcacgggcgg aaggctggac acgcgcccgc
    24301 gccgcggacc tgcgcacggt gctcacccgg ctgacgcgcc tggaccgggg tgagcccgat
    24361 ggaaccctgg ccggacgcct cgacaccggc cgcgtggcgg tggccggcca ctccatcggg
    24421 ggcgcggcag ctctgcagg
//
