LOCUS       NZ_KB891297            31274 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces sp. ScaeMP-e10 B061DRAFT_scaffold_1.2, whole genome
            shotgun sequence.
ACCESSION   NZ_KB891297
VERSION     NZ_KB891297.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. ScaeMP-e10
  ORGANISM  Streptomyces sp. ScaeMP-e10
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1282049)
  AUTHORS   Stepanauskas,R., Sieracki,M., Masland,D., Poulton,N., Swan,B.,
            Garcia,M.M., Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C.,
            Tapia,R., Chen,A., Kyrpides,N., Mavromatis,K., Markowitz,V.,
            Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G., Pagani,I.,
            Pati,A., Goodwin,L., Nordberg,H.P., Cantor,M.N., Hua,S.X. and
            Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Improved High-Quality Draft of Streptomyces sp. ScaeMP-e10
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1282049)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
REFERENCE   3  (bases 1 to 1282049)
  AUTHORS   Stepanauskas,R., Sieracki,M., Masland,D., Poulton,N., Swan,B.,
            Garcia,M.M., Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C.,
            Tapia,R., Chen,A., Kyrpides,N., Mavromatis,K., Markowitz,V.,
            Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G., Pagani,I.,
            Pati,A., Goodwin,L., Nordberg,H.P., Cantor,M.N., Hua,S.X. and
            Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. ScaeMP-e10
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            Isolation Site                    :: Gulf of Mexico
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 03:00:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,185
            CDSs (total)                      :: 7,109
            Genes (coding)                    :: 6,996
            CDSs (with protein)               :: 6,996
            Genes (RNA)                       :: 76
            rRNAs                             :: 6, 1 (5S, 16S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 45 of 113
            Pseudo Genes (incomplete)         :: 82 of 113
            Pseudo Genes (internal stop)      :: 12 of 113
            Pseudo Genes (multiple problems)  :: 23 of 113
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:33:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 139304
            Orig. end                         :: 170578
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB891297.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405355
            Source DNA and Organism available from Cameron  Currie
            (currie@bact.wisc.edu)
            Source DNA available from Cameron  Currie (currie@bact.wisc.edu)
            Organism available from Cameron  Currie (currie@bact.wisc.edu)
            Contacts: Cameron  Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31274
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="(micKC and not PKS_KS)"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..31274
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-iii"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22595
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22595
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12595](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12595
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(104..892)
                     /locus_tag="B061_RS0109485"
     CDS             complement(104..892)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959340.1"
                     /locus_tag="B061_RS0109485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_018511302.1"
                     /transl_table=11
                     /translation="MKLAFSTLGVPGMPVAEVARLAAEHGYEGVELRAHAEEPVHPGLS
                     SLERADVVEAFKAAGVEILTVAGYVQVAAEGDDEAVSADLADLVKLARDLGARYVRVFP
                     GGGDQDPADADATAARRLGSAAPAAADMGVSILLETHDSHRAGADVARVVGTVGHPRIG
                     AIWDVLHTWLADEDPAASHAVLAPHLGYVQVKDVASADDLTPLPLGAGTLPLAACLEPL
                     DPDGWVCWEYEKRWHPDAADLPGLLSAGREHLLRLGAPKQ"
     misc_feature    complement(877..891)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            complement(1083..1664)
                     /locus_tag="B061_RS0109490"
     CDS             complement(1083..1664)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010062910.1"
                     /locus_tag="B061_RS0109490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GAF domain-containing protein"
                     /protein_id="WP_018511303.1"
                     /transl_table=11
                     /translation="MTPKTESAPASSPLSPATSDTPRNELLQSVVEVARAIFGAAASSV
                     LLLDEETDELVFGAVSGEGQDFLVGRRFPAGRGIAGWVAASGEPMVVDDLSTDPSFDRS
                     LAESTEYVPDSLMAAPLISDSRVLGVLEVLDASPQARSNVRELDLLAMFARQAAAALRV
                     ITPERALEGAVREDALRLLGSLEQVLRGTG"
     gene            complement(1648..2565)
                     /locus_tag="B061_RS0109495"
     CDS             complement(1648..2565)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608641.1"
                     /locus_tag="B061_RS0109495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_026241345.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 6.5e-23, bitscore:
                     77.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAAGETTAATRPAPGQGLTWSLRGRGPEDVPVLGDPGPPGGHPT
                     GPATGRGVRVCVVDSGVERDHPLVGEPAASWVVVKDAESGEITVEPTTTGDTCGHGTAC
                     AGIIRRTAPECEIHSVRVLGERFSGTGDILMAGLRWAVEQRFDVVNLSLSTTRTRFAQE
                     LHSLADSAYFARTVIVASAHNTPVESFPWRFASVISVGSHQEDDPALHLYNPQPPVEFF
                     GPGQNVTVPWLGGRTIRTTGNSFATPYVAGLCARLLSAHPRMTAFQLKNALYLSAANVR
                     HEPSAQRPPHPSTAAGDTRDDSED"
     gene            complement(2569..5748)
                     /locus_tag="B061_RS0109500"
     CDS             complement(2569..5748)
                     /GO_process="GO:0009190 - cyclic nucleotide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0035556 - intracellular signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380877.1"
                     /locus_tag="B061_RS0109500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="WP_018511305.1"
                     /transl_table=11
                     /translation="MTCPSCRQELPSTARFCSSCGTPCAGPAAALAPAPVAPTAEDERK
                     PVTVLFCDLVGSTALSGVLDPETLRAVTLRYFEAMSAQIVARGGTPEKFIGDAVMAVFG
                     VPVVREDDARRALAAALGMRRALDALNEELYASLGIRLTTRVGVNTGQVVAGSDATARQ
                     ALVSGEVVNIAARLEQNAGPGEILIGPQTLLAAGPTVTAEPTGPLQLKGKRDSVEAYRL
                     LALGADDPELLRRFDAPFVGRTTELEALGRSLDETVREGRPGLLRVTGEAGIGKTRLVR
                     EWLTRRSGAGAFAYGAGRCRTYGDHGTLAPLADAVRSLLPHAQAPGDEATDDAMALLSG
                     GLLRDGTPNAPFEDMCAALTVVLKRTARDRPVVLVFDDWHAAAPLLVRTVDRLTGDAGP
                     ARVLVICAGRPEEAQGTRAADGRRGHLQLTGLPREEAARLAAGLARLDGRPAPADDRLL
                     ARAEGNPLYLEQLLVDDGTATASTSEGELPPTLQALLGARIGALARAERGVVDLAAVIG
                     REFAAAELVRLELSVRTAEQPGAVTAQGPGDRRRVDEALAALALRRLVEPAPSGAGEPS
                     AYRFSSGLVHEVAYASLSKRAKAERHAWAAELPSVLRTGDGAVGGHLERAYRYRTELGL
                     LDDRARLLRDRAAAALGRAGAQAAARSDLHWAHGLLERAVELRPDAAGALLGLGEVRVA
                     LGRVAEGAELLRKVRDLPTAPVEAAHARLALAVLDPAARPGTAATARAVLPVFEAAGDA
                     VGRARAHLRLAQQLQQSGRHEEAERDHARALEHAVEAGAEPERAGALGAIGISLWRGPV
                     PVPDAVERCRALLAAHGSGRPTVRVTLNCPLAVLYGLQDRADDAFACLAEAERLAGKLG
                     FAEAKVFLPVFRATVEALLGRGAEALALLARADAAARRMGAAGMRTAVALDAARLELDA
                     GHRNRAAGWLASIGDASELSRADAVDLEGLRARLAARTRPDEALHHADRAVRASLLTDS
                     PLVQAAAELDRARTLAALDRTAAAEAAARSAGAHFAGKGHLPGTRRVAAFLAAHTGPAA
                     MATTSTTREGS"
     misc_feature    5937..5953
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.61"
                     /tool="antismash"
     gene            complement(6037..6264)
                     /locus_tag="B061_RS0109505"
     CDS             complement(6037..6264)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959336.1"
                     /locus_tag="B061_RS0109505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aroma-sacti cluster domain-containing protein"
                     /protein_id="WP_026241346.1"
                     /transl_table=11
                     /translation="MTGPPAHSDQPEQRPVAAVLHEAGFPVDLLTEEQRVVLSELTPQE
                     LTLLLDVKNRLDAVGPEVQAHGEIAGGALF"
     gene            complement(6261..6902)
                     /locus_tag="B061_RS0109510"
     CDS             complement(6261..6902)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766799.1"
                     /locus_tag="B061_RS0109510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="WP_234017779.1"
                     /transl_table=11
                     /translation="MWRPEGLLPRYRTYLCTMHAVIRASVPLMELALRRTAETPGDPLS
                     EPLATYLAEHIQEEAGHDAWLLEDLLAAGATPEDALGPQPPADVATLVGPQYYWIEHHH
                     PVALLGYIAALEGYAPAPGLTDRISRLTGLPPAALRTVREHAALDTGHLDELHALLDRL
                     PLTRDQEAAVAVSALHSLDALTRLFVRLGRSAPAPSLRGAGPTPPTGVTR"
     gene            complement(7019..8089)
                     /locus_tag="B061_RS0109515"
     CDS             complement(7019..8089)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046103.1"
                     /locus_tag="B061_RS0109515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_018511308.1"
                     /sec_met_domain="PF04055 (E-value: 6.8e-12, bitscore: 42.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELAELVGLRPFPAAGLLLGLTRRCPLRCGHCSTGSDLTVREEPD
                     AGQLLRFVGSFTAENRPDVVLLTGGEPLLLPTLAGELAFLARRAGSRTAVLSGMFFARS
                     KEIPPAILRAIAQVDHFSASLDVHHEREVARADVFRALHRIRDTGVSVSFHLTGTGAAD
                     PYLADITRAIDKEFGGRVPSLVNEVRPFGRAASWARPARTGPDPSAAAPCSMAAWPVVA
                     FDGTVLACCNQDTVDRRPAPAHLDLGHIGSADWETVRRRALESPVLRMIRTVGPTHLAA
                     RSGAAPHPGSYCDGCRALAGDEAVAAGAQAVAAGPAGALLDLAAAQRGASGGPEGVVRR
                     HGCSAYAPLVGAGSAP"
     cand_cluster    7996..31274
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    7996..31274
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[17995:21274](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(17996..21274)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
     gene            8413..8574
                     /locus_tag="B061_RS39730"
     CDS             8413..8574
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969051.1"
                     /locus_tag="B061_RS39730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018511309.1"
                     /transl_table=11
                     /translation="MSENTKPAAGDTNENETPEVEAHSVLDLQETPGVIDREIVPGNCV
                     STVSLVLG"
     CDS_motif       8413..8538
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSENTKPAAGDTNENETPEVEAHSVLDLQETPGVIDREIVPG"
                     /locus_tag="B061_RS39730_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8539..8574
                     /prepeptide="core"
                     /locus_tag="B061_RS39730_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="1037.2"
                     /monoisotopic_mass="1036.6"
                     /core_sequence="NCVSTVSLVLG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSENTKPAAGDTNENETPEVEAHSVLDLQETPGVIDREIVP
                     G"
                     /leader_location="[8412:8538](+)"
                     /alternative_weights="1055.2"
                     /alternative_weights="1073.3"
     gene            8679..9989
                     /locus_tag="B061_RS0109525"
     CDS             8679..9989
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450772.1"
                     /locus_tag="B061_RS0109525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_018511310.1"
                     /transl_table=11
                     /translation="MATPLRSNRDFRLLWLSGLFAVLGGQMSALALPLLILRTTGSAVQ
                     AGAVGTVSVCALLVTMLPGGVMADRVERRRLMRLCDAGSLAAVTALTIAVWYGHAPMVL
                     VLLVATSGAVLSSVYAPAAFGLMRAVVPPDQMGTATARLQARTATVRMAGPLVGGALFG
                     IHEALPFAAQFLGLLLSTLCIALVRTRSAAQTRAGSVFSRRELTAGLTFLWQLPYLRTV
                     LLVFGLGMNFAFGALTFTALAVFSDNGTSGLGSGFVITCVSAGSLAGALLAPKIAPDRH
                     ARALIIATCWSCVLTAAALAWISSAVLAGVLCALCMALSTIASIGFLSTLLIVTPEDRI
                     GRVQSAAGFLSSIVQPFGPLAGGLLLATLGTRSAFGVIGCVLAVSAAVVTLSSAVRAGA
                     SPPPEKPERPETTEEPPARTAAAAPPAHDAAAGPGAL"
     gene            10001..12595
                     /gene="lanKC"
                     /locus_tag="B061_RS0109530"
     CDS             10001..12595
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046100.1"
                     /locus_tag="B061_RS0109530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_018511311.1"
                     /sec_met_domain="micKC (E-value: 8.5e-218, bitscore: 721.4,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.6e-08, bitscore: 30.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVSGIQQTQLYCLADPTYYETPARLPDEKTRYPLDSAPPHEGWR
                     RVRGGLWTSLLPEGRELAEQGWKIHVSTVPEEAEATLRDTARICLAHGVPFKFLRSEQA
                     LLLMSDKYMARSGAGKFLTLYPPDETVFLRVLDELTHALAGRRGPYILSDLRIGDAPVY
                     VRYGAFTARWCLDADGERVHALRHPSGELVPDERGVVFRVPRWVTVPEVLRPHLAARAA
                     SGDATFPYTITESLQFSNAGGIYLARHHETGRRVVLREARPHCGLDAVGDDAVTRLHRE
                     HRALTALAGLDCVPEVYAVRRVWEHHFLIEEHIEGATLLEEIVGRFALLHGSGTTAELA
                     AYTAWVDSVTERLTQALAAIHARGLRFGDLHPSNVIIRPDGRVVLIDFEYATALDDQDT
                     PVAGAPGLQAPTGTPGAEADAYALWATWLSMLMPLMEMAGHDRAKALTLERWARQRYGL
                     ASDAGPLRPAALVAAESRFGGESEIAALLEGPAPDWAELRARLIAGIHAGATPERTDRL
                     FPGDPAAFATGGIDVAHGAAGVLHALHRVGAPVEPAWTDWLAEAALRRDPAAPGGLYDG
                     LPGTAVVLSLLGRREEGRELFERATAAPPSASADLRSGRAGIALAALRLARPAGEGGAA
                     PDPDAKVDQELVEIAVRTADDLDRLVRGDSVPGLAVPASAGLLRGLSGAALLHLELHAL
                     TGEDRFLRAAGRALEREAGHCVTMPGGTVQVKDGRRHFLYLDQGSGGVALVAQAYLARR
                     PAPALSALLPGVRQGCVLEFVREPGLFTGRAGLMATAGQLSPQSRTEPDVLASARNLSW
                     HLIAQEDRLLVPGSRLRRCSADLATGAAGLLLALHFLSEASGPGLLELLTLG"
     gene            complement(12582..14495)
                     /locus_tag="B061_RS0109535"
     CDS             complement(12582..14495)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608633.1"
                     /locus_tag="B061_RS0109535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_018511312.1"
                     /transl_table=11
                     /translation="MIRPPARPAPAGTVYFSLLGPLTAVRDGRPLPLGPRKQRLVLATL
                     LARPNTPVPVDVLTDAVWPDDPPRTARKNLQVYVSAARALLGSDSRDGRDRVVHGCGGY
                     RLTIGEGELDTLRFRSLARAGRAAGERGDLRTAARLLREALDLWEGPPLNDLRDSTGVA
                     EEAERLEARCLTVYEDWAETEIELGRAAVAVDGLRDLVERHPLRERLRVAWMNSLHQSG
                     RQAEALAVYDDYRQLLARELGLEPSPAMAALYRAMLGRGRTARPAAAGREAAYGTALPA
                     APRDFTGRREELRELLALLGSPDERVVVVSGPVGSGKSALALRAAHLLGDGFPDGRFHV
                     QVRREDGSARTPAEVLGELGRLCGVRAPGGSGVPAESAVTAASAVAADSAVPADATVPA
                     VSQGAADAWQRWLSLHRALIVLDDVPDEAFVRGLLPRSGPSSVVLTARGQLAGLAPVHR
                     IALGALADGEALELLGKLIGPGRLRTDPAAALRIVRACGALPLAVGVGGMRLAVLRHLP
                     LAEYADRLGDPSAALDELVAGDISVRLRMASGWQDLSADDRRALGRLAGPAQEGGFTLD
                     GAMEALGCGERAAIRTVESLIDAGAVTSPAGEVTAHAALYEVPRLLCLYAREREEGRFS
                     PG"
     misc_feature    complement(14626..14640)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            complement(14686..17601)
                     /locus_tag="B061_RS0109540"
     CDS             complement(14686..17601)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124639.1"
                     /locus_tag="B061_RS0109540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_018511313.1"
                     /transl_table=11
                     /translation="MRATSPVIVGRDEEIGLLSSALDAVQRRSGRALFFLGEAGIGKSR
                     LVGEAAYRAYGLGMPVLRGRATSTGLVVPFRPLVEALSSRFRAAGTPTDPELAPYHPAL
                     ARLVPEWRQEASPGYPETVVELAEALLRLLSVLGRESGCAILLEDLHDSDTETVAVVEY
                     VIDNLADLPILLLGTLRPEAGAALDLVRSAERRQAASVRELKPLADEQMRTLTAACLEA
                     APEEIPQVVHHRLAERAGGNPYLVEVLLADLLDTGQLRRTGSGWEAAEQPGGPVPSGIV
                     RTWTRRLDRLDEPVRDLLLAAATLGGQFSVSVLQTVTGFEDRALFTHLRSAVEAGVIAP
                     DGAAPDRYAFRHSLTAEALISSLAPAERASLARRAAGAIEHSGHPLDEDGQQLVASLHL
                     AAGNRAGAALRFAEAGRRMLASGAHGSAVVLLERACPLAADADRAAISESLAVARAEGG
                     DLDAALELAESLPPVPARTEAAERRGEVHIKIAWVAVMAERAADAARQIEAARTLLGQD
                     PAPGRHAALTVADAHLALLPGQEHRRPGETERAAREAAEIAEAEGLPVVACQAWQLLAL
                     LLREKGFDEADACLERMLALSTDHGLPVWRVEALVRLGANAFMRTGDASRLRSARAAAI
                     ELGALLLTQTVDGLLAMNAVLCARWDEAQEIIDRSLEASARVGNLSAHRYLLLSTATMA
                     AHRGRRRDMDRALAAFRRAGGEPSLLVPHQLGLCKAIGALLEEDRERALAGLDAVLAWE
                     QDHPSYFYLSGSYGLRPFLRVLAGAADRAEFDAVRASPGAQLAWNGQFLELAEAVLLGR
                     EGDPAGADRLVASFDARAVPFPVARHLGLRLVADAAGADGWGEPVSWLRRSEEFFYGVG
                     AQAVASACRAALRQAGASVTQHRGGWDRIPLPLRTSGVTPREYEVFVLLPERPGNQQIA
                     RRLSISPRTVEKHMASLLSKTGRADRSALCEFAAECAAEPA"
     misc_feature    complement(16705..16707)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17674..17868)
                     /locus_tag="B061_RS0109545"
     CDS             complement(17674..17868)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608631.1"
                     /locus_tag="B061_RS0109545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018511314.1"
                     /transl_table=11
                     /translation="MTHISESAIQGSGNLAHEGAYDHPAGQISLGIGGGLGMRSRLLSA
                     SEGETGNTIDLPWTTMIPL"
     gene            complement(17996..21274)
                     /locus_tag="B061_RS0109550"
     CDS             complement(17996..21274)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608630.1"
                     /locus_tag="B061_RS0109550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_018511315.1"
                     /sec_met_domain="DUF4135 (E-value: 2.2e-103, bitscore:
                     342.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1e-26, bitscore: 89.6,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKELIGSGGTGAAARLALPGTHGSAGANGSARPAGSVGAAVANG
                     TSTSAAPSASPQAAVTTAGAARTDHRNTGHPNNTNTDHAHMDHADMDHPYADHANANHP
                     RTNTGSSTPAPTTPRANPWWLPGVVGEPPMGEPDWVVFVRAVIADAPAEAVVAGREYPG
                     LSGFALVVAPFAERAAGRLLTSPSNNAVRAGTAVGLAPVLEDFRSHLVGRLARLAARTL
                     VLELHKARRAGRLAGEGPQERFRDFVRRTAGRDGLAAFLTAYPVLARILARASLAAADA
                     FTEMLGRLADDRELLASSGVLGDRGHGASPGTLAAGRGPGALTGVEAGAGDSHRGGRSV
                     MLLRFTDGSRLVYKPRPPAAHRHFNSLVEWFGSLPGTPSLRALRVLDRGEYGWVEYVEE
                     RPCSSASDTHLFYRRQGALLALLHLLDGTDLHQENLIACGPHPVLVDVETLFHPPLSQA
                     HSSDPAARALHASVHRVGLLPQLLVGDAAALDVSAIGGGRAAPSPIETADWADAGTDTM
                     RLVRRSARFTESANRPRLEGVPADPSAYTDALCEGFRAGYTAISDHRDDLLGKRGLLTD
                     FAQDEVRVVPRPTWTYTTLLDESTHPDLMRDAAERHQVLSLLRTPALGVPALPGLEDEE
                     IEELWAGDVPVFLTRPGSPDLWSGTGREVPPTPGPTGLARVEAKVRAMDTVDRQDQERI
                     IRAAMVSTSPELPHRAEGGARPRMAATAPEPEQLLSAARSVGDQLVSLAYRHEARTNWI
                     GLELLGERYWRLAPMAADLASGYTGPALFLAQLAALTGADRYAEAAREALTPVPGLLDA
                     LHGRADDLAVLGSGAFAGLGGIAYALAEVGSLLGDRTVLDLAGPATRLACAASVAEEGY
                     GVRGGAAGGLVSLLAVHRTTGRAEAWRGAERCAERISVAPHPAAGGFAEGAAGIGWALL
                     RFAAAGGGEQYRTAGLRALRRATVEVTAGRAWCEGAAGVALAVADSSDALVDPDLSGWL
                     AERAGELADCAPLADDSLCHGELGLLELLGHPALTGDRTPWVRRAGTLLAAADREGPRC
                     GTPGHVPHPGLLTGLSGIGHGLLRAGFPDRIGSALLLNPSSGVA"
     gene            complement(21498..22577)
                     /locus_tag="B061_RS0109555"
     CDS             complement(21498..22577)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608629.1"
                     /locus_tag="B061_RS0109555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_018511316.1"
                     /transl_table=11
                     /translation="MTVTLADVAARARVSPATVSRVLNGNYPVAASTRERVLRAVDDLD
                     YVLNGPASSLAAATSDLVGILVNDIADPFFGIMAGAAQTQIGGPGDGSGRAGGEKLAVI
                     CNTGGSPERELTYLTLLQRQRAAAVVLTGGAVEYPEHQAAMAAKLAKMADAGTRIVFCG
                     RPPLPEGDALVAALAFDNRGGGRRLTEHLISLGHRRIGYVAGPPERTTTRHRLEGHREA
                     LRGAGLDDAEAGDEERLTVHGPYDRRSGYEATLEILRRDPAVTAVVAANDTVALGACAA
                     VRDQGLRIPQDISVAGFDDLPFSVDAVPALTTVRLPLFEAGARAGRLAMGKENPPPGGI
                     ATIAAELMIRGSTAPPRVG"
     misc_feature    complement(22573..22584)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 14.95"
                     /tool="antismash"
     misc_feature    complement(22653..22664)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            22688..23839
                     /locus_tag="B061_RS0109560"
     CDS             22688..23839
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005317389.1"
                     /locus_tag="B061_RS0109560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_043184763.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 3e-10, bitscore:
                     36.9, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.3e-26,
                     bitscore: 89.1, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRTVRIAMNGVTGRMGYRQHLVRSILAIREQGGLDLGDGEVLW
                     PEPVLVGRRTHALEELAARHGLTEWSTDLDAVLADDTIDIYFDAQVTSARVEAIKKAIA
                     AGKHIYTEKPTATDVEGALDLARLARDAGIKHGVVQDKIFLPGLLKLKRLIDGGFFGEI
                     LSIRGEFGYWVFEGDWQEAQRPSWNYRTEDGGGIVVDMFPHWEYVLHELFGQVTSVTAH
                     VQTHVPQRWDEHGKPYEATADDAAYGIFQLAGGAVAQINSSWTVRVNRDELVEFQVDGT
                     HGSAVAGLRNCRVQHRSSTPKPVWNPDLPVTESFRDQWQEIPDNQEFANGFKAQWELFL
                     RHVALDEPYTWDLLAGARGVQLAELGLKSSAEGRRFEVPELTL"
     gene            23836..24993
                     /locus_tag="B061_RS0109565"
     CDS             23836..24993
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124633.1"
                     /locus_tag="B061_RS0109565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_018511318.1"
                     /transl_table=11
                     /translation="MTATVALPWGPYTPRATPLDLPPPTGLPPTSRTVFSAAHVVADPY
                     ADISPDDPAAVDWESTLAFRRHLWSHGLGVAEAMDTAQRGMGLDWAGAAELIRRSAAEA
                     KAVGGRIACGVGTDQLRPSAEPTLAEVRSAYEEQLALAEANGVQPILMASRALAKAARG
                     PEDYLATYAHLLRQSGEPVILHWLGPMFDPALEGYWGSADLDEATDTFLRVIAEHPDKV
                     DGIKISLLDAAREIDVRRRLPSGVRCYTGDDFNYPVLIAGDERGFSHALLGIFDPLGPL
                     AAHAVRVLDTGDAAGFRALLDPTVELSRHLFRPPTRFYKTGVVFLAWLAGHQDHFTMVG
                     GSQSARSLPHLAKAYELADGLGLFPDPDLAAHRMRALLTVSGGAR"
     gene            24990..25826
                     /locus_tag="B061_RS0109570"
     CDS             24990..25826
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969065.1"
                     /locus_tag="B061_RS0109570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_018511319.1"
                     /transl_table=11
                     /translation="MNGEHLARLSLNQETIKQWSLPELAEGCVKAGIGKVGLWRAPVQA
                     YGVDRTARLLADAGLTVTSLCRGGFLTALDPADRAAALDDNRRAIDEAAALSTGTLVLV
                     SGGLPPGSRDLYGARERVGDALAELAPYAAGRGVRLAIEPLHPMFASDRCVVSTLAQAL
                     DLAERFPAEQVGVVVDTYHVWWDDRAPEQIARAGAGGRIHSFQLADWITPLPAGVLLGR
                     GQLGDGSVDFRAWRTEVEAAGFDGPIEVEIFNETLWTRDGAEVLAEVAERYVQHAC"
     gene            complement(26104..26526)
                     /locus_tag="B061_RS0109575"
     CDS             complement(26104..26526)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489615.1"
                     /locus_tag="B061_RS0109575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNHCP domain-containing protein"
                     /protein_id="WP_026241348.1"
                     /transl_table=11
                     /translation="MTRRGARSGGARRPQRPKDVLHGPVGARGDAFRCVGCRLDVSLVA
                     PGTAHRNHCPSCLVSLHVDRRVPGDRAAGCGGRMTALSLSVRADGEWMLIHLCLTCDEL
                     SANRIAGDDNALALIRLALRPLADAGIPASRVMLAL"
     gene            complement(26523..26864)
                     /locus_tag="B061_RS0109580"
     CDS             complement(26523..26864)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056535.1"
                     /locus_tag="B061_RS0109580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNHCP domain-containing protein"
                     /protein_id="WP_043184867.1"
                     /transl_table=11
                     /translation="MSSLSTFTCVRCGLTVAAFAPDGSRRNHCPSCLHSQHLVDHVEGG
                     PSDCEGRMTPISIAVLRTGDWMVVHRCVRCDELTSNPVCGDDNQLILMRMAVRPLAQPP
                     FPLEAFGDL"
     CDS             complement(27048..27227)
                     /gene="allorf_0166352_0166531"
                     /locus_tag="allorf_0166352_0166531"
                     /protein_id="allorf_0166352_0166531"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MFRNSVVRLPFPLLRCFRLVAVPTAGDLWAVCPGKQLMYAPVSDS
                     EPPSSRPRRRGDRA"
     CDS_motif       complement(27153..27227)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MFRNSVVRLPFPLLRCFRLVAVPTA"
                     /locus_tag="allorf_0166352_0166531_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(27048..27152)
                     /prepeptide="core"
                     /locus_tag="allorf_0166352_0166531_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.40"
                     /molecular_weight="3684.1"
                     /monoisotopic_mass="3681.9"
                     /core_sequence="GDLWAVCPGKQLMYAPVSDSEPPSSRPRRRGDRA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFRNSVVRLPFPLLRCFRLVAVPTA"
                     /leader_location="[27152:27227](-)"
                     /alternative_weights="3702.1"
                     /alternative_weights="3720.2"
                     /alternative_weights="3738.2"
     CDS             complement(27116..27247)
                     /gene="allorf_0166420_0166551"
                     /locus_tag="allorf_0166420_0166551"
                     /protein_id="allorf_0166420_0166551"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGVLLFLCSVIRWSGFLSRCYGASALSRCRPQVTSGPCALESS"
     CDS_motif       complement(27179..27247)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGVLLFLCSVIRWSGFLSRCYGA"
                     /locus_tag="allorf_0166420_0166551_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(27116..27178)
                     /prepeptide="core"
                     /locus_tag="allorf_0166420_0166551_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.60"
                     /molecular_weight="1941.2"
                     /monoisotopic_mass="1940.0"
                     /core_sequence="SALSRCRPQVTSGPCALESS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGVLLFLCSVIRWSGFLSRCYGA"
                     /leader_location="[27178:27247](-)"
                     /alternative_weights="1959.2"
                     /alternative_weights="1977.2"
                     /alternative_weights="1995.2"
                     /alternative_weights="2013.2"
     misc_feature    27218..27236
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.86"
                     /tool="antismash"
     gene            27246..27746
                     /locus_tag="B061_RS0109585"
     CDS             27246..27746
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019764883.1"
                     /locus_tag="B061_RS0109585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TspO/MBR family protein"
                     /protein_id="WP_018511322.1"
                     /transl_table=11
                     /translation="MPQTPTTPTTPATPRRWLTLLLLLALCYGVAAAGAVATGDAGSTY
                     AALDRPAWAPPGWLFGPVWTVLYGMIAVAGWLVARRPGPGRRPALVAWGVQLALNALWT
                     PLFFAAEQYGLAFLDIALLLAAVVTTALLCARVDRRAAWLLVPYLLWVGYAAALNLALW
                     LTN"
     gene            27820..28557
                     /locus_tag="B061_RS0109590"
     CDS             27820..28557
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511323.1"
                     /locus_tag="B061_RS0109590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_018511323.1"
                     /transl_table=11
                     /translation="MTSSERWTRATADRYDAEETENSSAAVLHPTLDFLAELAGDGRAL
                     EFAIGTGRVGVPLRERGVPVVGIELSEHMAAVLRRKVDESTLPVTIGDMTTTIVPGGFT
                     LVYLVYNTISNLLTQEEQVECFRNAARHLEPGGRFVIELEVPPLRSLPPGQTAVPFDVS
                     ERHLGFDTFNLVDQIQVSNHFTREADGRYRRGNSRHRYAWPAELDLMARIAGLERERRV
                     ADWDGTPFTQDSTKHISAWRKPT"
     misc_feature    28576..28594
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.08"
                     /tool="antismash"
     gene            28756..29022
                     /locus_tag="B061_RS0109595"
     CDS             28756..29022
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152921.1"
                     /locus_tag="B061_RS0109595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018511324.1"
                     /transl_table=11
                     /translation="MAFIKRVALAPRAVRQLRRVRSVYAVGMALSLLGLLLQVERDPGG
                     RQTHLAAMILVAFVALFGLTAVQLWRHMRTAHCSTAKKLTASV"
     gene            complement(29109..29720)
                     /locus_tag="B061_RS0109600"
     CDS             complement(29109..29720)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="B061_RS0109600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_018511325.1"
                     /transl_table=11
                     /translation="MDAEHIDGRTVRYQHRRPELLGAVADYVLEHGVSGLAMRPLAGAV
                     GVSHGTLLHHFGSKENLLTEVIELLRQRLAQAADLADSPRDLTSLTRWWRTTTGPDDMA
                     VYRLLFEVHALAVREPERYSRHLQRAAHDSLALMESLVVAEGCPADQAPLVASMIVAQA
                     RGLQLDLLATAERDRVDRSFALFVELIGRLRLTWHPEEQA"
     misc_feature    29751..29766
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.15"
                     /tool="antismash"
     misc_feature    complement(29763..29776)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.67"
                     /tool="antismash"
     gene            29788..30783
                     /locus_tag="B061_RS0109605"
     CDS             29788..30783
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024859.4"
                     /locus_tag="B061_RS0109605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_026241350.1"
                     /transl_table=11
                     /translation="MSHDMGRLHHVGHVVRDMGEALDLYRRLGFTLAPPAYPAMAPSEG
                     AAPEPFGAANTQADFPRTFVELVTCVPQGGAARVPSEAKLVPLRAPAELLPQLVERISS
                     TSATIAAALERFEGLHILMFSSPDIDVAAARLSAARVAHGGVNTVHRAVETADGTRTES
                     VRYLEIDSPEPAVGPGAVAEGRVGVVADLDPLVQAARQLDHPNGAFDLVEVVTCVAEAG
                     LDAMAARYQDYLGSPARADGPSRFFDLDGSRLTLVPDSHLATTLPGEHAPAVPAFVAYA
                     VAMRDLAATRKLLRDNGFPVGRTDAGDIFVPAASALGAAIIFREGSQVRR"
     CDS             complement(30956..31192)
                     /gene="allorf_0170260_0170496"
                     /locus_tag="allorf_0170260_0170496"
                     /protein_id="allorf_0170260_0170496"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVPAHAGVVLRSAPSRPTRSGGPRAGGGVPSLGDLFVESEAWSPR
                     GRGFRGGGRRRGAGAGASCCTICARIRSRCSVW"
     CDS_motif       complement(31007..31192)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MVPAHAGVVLRSAPSRPTRSGGPRAGGGVPSLGDLFVESEAWSPRGRGFRGGGRRRGAG
                     AGA"
                     /locus_tag="allorf_0170260_0170496_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(30956..31006)
                     /prepeptide="core"
                     /locus_tag="allorf_0170260_0170496_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.30"
                     /molecular_weight="1772.1"
                     /monoisotopic_mass="1770.8"
                     /core_sequence="SCCTICARIRSRCSVW"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVPAHAGVVLRSAPSRPTRSGGPRAGGGVPSLGDLFVESEA
                     WSPRGRGFRGGGRRRGAGAGA"
                     /leader_location="[31006:31192](-)"
ORIGIN
        1 gtggcgctga cctcgctggg aggggtgcgg ggccgggggg tcgggactgc ctcggcgccc
       61 gcccccgtac ggcctgccgc ttcgcagccc ccggccgtcg gccctactgc ttcggcgccc
      121 ccagccgcag cagatgctcc cgccccgcgc tgagcaggcc cgggaggtcc gccgcgtccg
      181 ggtgccagcg cttctcgtac tcccagcaga cccacccgtc cgggtccagc ggctccaggc
      241 aggcggccag tgggagggtg cccgcgccga gggggagcgg agtgaggtcg tccgccgatg
      301 cgacgtcctt cacctgtacg tagccgaggt gcggggccag caccgcgtgg ctggcggccg
      361 ggtcctcgtc ggccagccag gtgtgcagga cgtcccagat ggccccgatc ctggggtggc
      421 cgacggtgcc cacgacccgg gccacgtcgg cgccggcgcg gtgggagtcg tgggtctcca
      481 gcaggatgga gacgcccatg tcggcggcgg ccggggcggc cgagcccagg cggcgggcgg
      541 ccgtcgcgtc cgcgtccgcc gggtcctggt cgccgccgcc ggggaagacc cggacatagc
      601 gagcgcccag gtcccgagcg agcttcacca ggtcggccag gtcggcggag acggcctcgt
      661 cgtcgccctc ggccgccacc tggacgtacc cggccacggt caggatctcc accccggccg
      721 ccttgaacgc ctcgaccaca tcggcccgtt cgagggagga gaggcccggg tgtaccggct
      781 cctcggcgtg ggcgcgcagt tccacgccct cgtaaccgtg ctctgcggcg agccgggcga
      841 cctcggccac cggcattccc ggcaccccga gagtggagaa agcgagcttc acgtgcgtgt
      901 ccttcccatc gtgaccgcgc gggaacgtgt ccggcgcctg ccccgggctc ctgcccgcag
      961 cccggtgccg tacgcgtacg gaccccgggc ccgtacgtgt acggcaggcg tccgggccgg
     1021 tgacccgcac gcgtacggca agcgcgtctc agccggtgac ccgcacgcgt acggcaagcg
     1081 tctcagccgg tgccccggag cacctgctcc aggctaccga gcagccgcag cgcgtcctcg
     1141 cgcaccgcgc cctccagcgc ccgctccggg gtgatcaccc gcagcgcggc cgccgcctgc
     1201 cgggcgaaca tcgccagcag gtccagctcc cgcacgttgg agcgggcctg cggggacgcg
     1261 tccagcacct ccaggacgcc gagcacacgg gagtcgctga tcagcggggc cgccatcagg
     1321 gagtcgggga cgtactcggt ggactcggcc agcgagcggt cgaaggacgg gtcggtcgac
     1381 aggtcgtcca ccaccatcgg ctcgcccgag gccgccaccc agccggcgat cccccgcccg
     1441 gccgggaacc ggcgccccac caggaagtcc tggccctccc cggagaccgc cccgaagacc
     1501 agttcgtccg tctcctcgtc gagcaggagg accgagctcg cagccgcgcc gaagatggcc
     1561 cgggccacct cgacgaccga ctggagcagc tcgttgcggg gggtgtcgga ggtggcgggg
     1621 gagagcgggg aggaggcggg ggcggattca gtcttcggag tcatcgcggg tatctcctgc
     1681 cgctgttgag ggatgcgggg ggcgctgggc gctcggctcg tggcgcacat tggccgccga
     1741 cagataaagg gcgttcttga gctggaaggc cgtcatccgg ggatgcgccg acagcaggcg
     1801 cgcgcagagc ccggcgacgt acggcgtggc gaagctgttc ccggtggtgc ggatcgtccg
     1861 gccgcccagc cacggcacgg tgacgttctg gcccggcccg aagaactcca cgggcggctg
     1921 agggttgtag aggtggaggg ccgggtcgtc ctcctggtgg ctgccgacgg agatcaccga
     1981 cgcgaaccgc caggggaagc tctccaccgg ggtgttgtgg gccgaggcga cgatcaccgt
     2041 acgggcgaag taggcgctgt ccgcgaggga gtggagctcc tgcgcgaacc gggtccgggt
     2101 ggtcgacagg ctcaggttca ccacgtcgaa gcgctgctcc accgcccagc gcagccccgc
     2161 catcaggatg tccccggtgc cggagaaccg ctcgcccagc acccggacgc tgtggatctc
     2221 gcactccggc gcggtccggc ggatgatgcc cgcgcacgcg gtgccgtgcc cgcaggtgtc
     2281 gccggtggtc gtcggctcga ccgtgatctc cccgctctcg gcgtccttga ccaccaccca
     2341 ggaggcggcc ggttcgccga ccagcggatg gtcgcgttcc acgccggagt ccaccacgca
     2401 gacgcgtacg ccgcgtccgg tggcggggcc ggtggggtgg ccgcccggtg gtcccgggtc
     2461 gcccaggacg ggcacgtcct cggggccgcg cccgcgcagg ctccaggtca ggccctgccc
     2521 cggggcaggc ctcgtagcag ctgtggtctc tcctgcggcg cccatcggtc agctcccttc
     2581 cctcgtcgtg ctcgtcgtgg ccatggctgc gggtcccgtg tgtgccgcga ggaaggccgc
     2641 cacccggcgg gtccccggca ggtgcccctt gcccgcgaag tgcgccccgg cgctccgggc
     2701 cgccgcctcg gcggcagccg tgcggtccag cgcggcgagg gtgcgggccc ggtccagttc
     2761 ggcggcggcc tgcaccagcg gtgagtcggt gaggagcgat gcgcgtacgg ccctgtcggc
     2821 gtggtgcagc gcctcgtccg ggcgggtccg ggccgccagc ctggcccgta gcccctccag
     2881 gtcgacggcg tccgcccggc tcagctccga cgcgtcgccg atgctcgcca gccaccccgc
     2941 cgcccggttc cggtgccccg cgtccagctc cagccgggcc gcgtccagcg ccacggccgt
     3001 ccgcatcccc gccgccccca tccgccgggc cgccgcgtcc gcccgggcca gcagggccag
     3061 ggcctccgcg ccccggccga gcagcgcctc cacggtcgcc cggaacaccg gcaggaacac
     3121 cttcgcctcc gcgaacccga gcttccccgc cagtcgttcc gcctccgcca ggcacgcgaa
     3181 cgcgtcgtcg gcccggtcct ggagtccgta cagcacggcc agcgggcagt tgagcgtgac
     3241 ccggaccgtc ggccggccgg acccgtgggc cgccagcagg gcgcggcacc gctccaccgc
     3301 gtccggcacc gggacgggcc cgcgccagag cgagatcccg atcgcgccca gggccccggc
     3361 ccgctccggc tcggctccgg cctccaccgc gtgctccagg gcccgcgcgt gatcccgctc
     3421 cgcctcctcg tggcggcccg actgctggag ctgctgggcg aggcggaggt gggcgcgggc
     3481 ccggccgacc gcgtcccccg cggcctcgaa gaccggcagc accgcgcggg cggtggcggc
     3541 ggtgccgggg cgcgccgccg ggtccagcac cgccagcgcg aggcgggcgt gcgcggcctc
     3601 cacgggtgct gtgggcaagt ccctgacctt ccgcagcagt tcggctccct ccgcgacccg
     3661 gccgagcgcc acccgtacct cgccgagccc cagcagcgcc cccgccgcgt ccggccgcag
     3721 ctccaccgcc cgctccagca gcccgtgcgc ccagtgcagg tcggagcggg cggcggcctg
     3781 ggccccggcc cggcccagcg cggcggcggc ccggtcccgc agcagccggg cccggtcgtc
     3841 cagcagtccc agctcggtgc ggtagcggta ggcgcgctcc agatggcccc cgaccgcgcc
     3901 gtcgccggtc cgcagcacgc tcggcagctc ggccgcccac gcgtggcgct ccgccttggc
     3961 ccgcttggag agcgaggcgt aggcgacctc gtggaccagc ccgctgctga accggtacgc
     4021 cgacggctcc ccggccccgg acggcgcggg ctccaccagc cgccgcaggg ccagcgcggc
     4081 gagcgcctcg tcgacacggc gccggtcccc gggcccctgc gcggtgacgg ccccgggctg
     4141 ctcggccgtt cgtacggaca gctccagccg caccagctcc gccgccgcga actcccggcc
     4201 gatcacggcc gccaggtcca ccaccccgcg ctcggcccgg gccagcgccc cgatccgggc
     4261 gcccagcaag gcctggaggg tgggcggcag ctccccttcc gaggtcgagg cggtggcggt
     4321 cccgtcgtcg acgaggagct gctccagata gagcgggttg ccctcggcac gggccaggag
     4381 ccggtcgtcg gccggggcgg ggcggccgtc cagccgggcc agaccggcgg ccagccgggc
     4441 tgcctcctcc cgggggaggc cggtgagctg gaggtggccc cgcctcccgt cggccgccct
     4501 cgtgccctgt gcctcttccg ggcggcccgc gcagatcacc aggacccgcg cgggcccggc
     4561 gtcgcccgtc agccggtcca ccgtccggac cagcaggggc gccgccgcat gccagtcgtc
     4621 gaacaccagg accaccggcc ggtcccgggc ggtccgcttc aggaccacgg tcagcgcggc
     4681 gcacatgtcc tcgaaggggg cgttcggcgt gccgtcgcgc aggaggcccc cggagagcag
     4741 ggccatcgcg tcgtcggtcg cctcatcccc aggggcctgg gcgtgcggga gcagggagcg
     4801 tacggcgtcg gcgagcggcg ccagcgtgcc gtggtccccg taggtgcggc agcggcccgc
     4861 cccgtacgcg aaggcgcccg cgccgctccg gcgcgtcagc cactcccgta ccagccgggt
     4921 cttgccgatg cccgcctcgc cggtcacccg cagcagaccg ggccggccct cccgtacggt
     4981 ctcgtccaac gaccgcccca gagcctccag ttcggtggtg cggccgacga acggcgcgtc
     5041 gaagcggcgc agcagctccg ggtcgtccgc ccccagcgcc agcagtcggt acgcctccac
     5101 gctgtcgcgc ttgcccttga gctggagggg gccggtgggc tcggccgtca ccgtggggcc
     5161 ggcggcgagg agggtctgcg ggccgatgag gatctcgccc gggcccgcgt tctgctcaag
     5221 gcgcgcggcg atgttgacga cctcgccgga gaccagggcc tggcgggccg tggcatccga
     5281 accggccacc acctgaccgg tgttgacccc gacccgggtc gtcagccgga tgccgagcga
     5341 ggcgtacagc tcctcgttga gggcgtccag cgcccggcgc atcccgagcg ccgccgccag
     5401 ggcccgccgg gcgtcgtcct cccggaccac cggaacgccg aacaccgcca tgaccgcgtc
     5461 cccgatgaac ttctccgggg tgccgccgcg cgccacgatc tgcgcgctca tcgcctcgaa
     5521 gtaccgcagg gtcaccgccc gcagggtctc cgggtccagt acccccgaca gggcggtcga
     5581 gcccacgaga tcgcagaaca gtacggtgac cggcttgcgt tcgtcttcgg cggtcggcgc
     5641 gacgggggcg ggggcgaggg ctgccgccgg accggcgcac ggcgtcccgc aggacgagca
     5701 gaaccgggcc gtggagggaa gctcctgtcg gcacgagggg caggtcatgg cgggtcctca
     5761 actctcctgg tccaactcgc cccggaggac ggtgcggtgg ctgatccggt cctggggcgc
     5821 ccgcgccgga cccccgtcct ggcgcgagcg cccccggcgc ccctagggcc tgtcgtcaaa
     5881 ctgccgcctg ccgggcgacg cctggcacgc acgctcgcgg cgttgccgaa atgccctggt
     5941 agctccgcta caagaccatt ccggcgcctt gcgatcgcac gcaccagacg ccgcacggcc
     6001 gccctccggg cgacgacggc agtttgtcga caggccctag aacagcgcgc cgcccgcgat
     6061 ctcgccgtgg gcctggacct cggggcccac cgcgtccagc cggttcttga cgtcgagcag
     6121 cagggtgagc tcctgcggtg tcagctcgct cagcaccacg cgctgctcct cggtgagcag
     6181 gtccacgggg aagcccgctt cgtgcaacac cgctgccact gggcgctgtt cgggctggtc
     6241 ggagtgtgca ggtggtccgg tcatcgggtg actcccgtcg gtggggtggg tccggctccc
     6301 cgcagcgacg gcgccggtgc ggagcgcccg agccggacga acagccgggt gagcgcgtcg
     6361 agggagtgca gcgcgctgac cgcgacggcc gcttcctggt cccgggtcag cggcagccgg
     6421 tccagcagcg cgtgcagctc gtccagatgg cccgtgtcga gcgccgcgtg ttcgcgtacg
     6481 gtccgcaggg cggcgggggg aagcccggtc agtctgctga tgcggtcggt cagcccgggg
     6541 gcgggcgcgt acccctccag cgccgcgatg tagccgagca gggccaccgg gtggtggtgc
     6601 tcgatccagt agtactgggg gccgacgagg gttgccacgt ccgccggcgg ctgcgggccg
     6661 agcgcgtcct cgggggtggc gcccgccgcg agcagatcct ccagcagcca ggcgtcgtgc
     6721 ccggcctcct cctggatgtg ctcggccaga taggtggcca gcggctccga caacgggtcg
     6781 ccgggcgtct ccgccgtacg ccgcagggcg agttccatca gcgggacgga ggcccggatc
     6841 acggcgtgca tggtgcacag gtacgtccgg tagcgcggca gcagcccctc cgggcgccac
     6901 atatgggtgg ttgctccccg gaactccggc tccagcagca gcagtttggt gcgcaggcgc
     6961 gtcgaagccg gttcgcgggg ggtggcgttc ggggcttcgc tgctcgtcca cgtgatgctc
     7021 acggcgcgct cccggcgccc accagcggcg cgtacgccga gcagccgtgc cgtcggacga
     7081 cgccttccgg cccgccgctc gcaccgcgct gcgcggcggc cagatcgagc agcgcacccg
     7141 ccggacccgc cgccacggcc tgtgctccgg ccgccaccgc ctcgtcgccg gccaacgccc
     7201 ggcacccgtc gcagtacgag cccgggtggg gcgcggcgcc ggaacgggcg gcgagatggg
     7261 tgggcccgac cgtacggatc atccgcaaca ccggggattc cagggcccgt cggcgtacgg
     7321 tctcccagtc ggcggagccg atgtgcccga ggtccagatg ggcgggggcg ggccgccggt
     7381 ccacggtgtc ctggttgcag caggccagca ccgtgccgtc gaacgcgacc accggccagg
     7441 cggccatcga gcacggcgcc gccgccgacg ggtcggggcc ggtgcgcgcg ggccgggccc
     7501 aggaggcggc ccggccgaac ggccgcacct cgttgaccag ggacggcacc cggccgccga
     7561 actccttgtc gatggcccgg gtgatgtcgg ccagatacgg gtcggcggcg ccggtcccgg
     7621 tgaggtggaa gctgacggag acccccgtat cgcggatgcg gtgcagggcc cggaacacat
     7681 ccgcgcgcgc cacctcccgc tcgtggtgga cgtccaggct cgcggagaag tggtcgacct
     7741 gggcgatcgc gcgcaggatc gcgggcggga tctccttcga gcgggcgaag aacatcccgc
     7801 tcagcaccgc cgtacgcgat ccggcgcggc gggccaggaa ggccagctcg ccggcgagcg
     7861 tgggcaggag cagcggctcc ccgcccgtca gcaggacgac gtccggacgg ttctcggcgg
     7921 tgaacgagcc cacgaagcgc agtagttgtc cggcgtccgg ctcctcccgc acggtcaggt
     7981 ccgacccggt cgagcagtgc ccgcaccgca gggggcagcg gcgggtgagg ccgagcagca
     8041 gaccggcggc cgggaagggc cggagtccga cgagttcggc gagttccata cgggccgcct
     8101 ccttcggggg ctggggcgcg cccggacttc gggggccggt gcgcacccgc ccaggctccg
     8161 ccgtaccggt tcaccggcgg tctggcatcg cttcaggacc ggtatacgcc caggtcagcg
     8221 aggccaggaa gccgccgggc ccctcggcgc ggcagccacc aacccccgcc gtactggccc
     8281 cataccggcc ccataccgga gccgaagcgt ctcccaggcc ggcgctccta actttctcgg
     8341 caacggcagg caacgggccg cggcgaacgc cacgagaacc gggccggcac acacgagtgg
     8401 acggagacca ccatgtccga gaacaccaag cccgcggccg gcgacaccaa cgagaacgag
     8461 acccccgagg tcgaggcgca ctccgtgctg gacctccagg agaccccggg tgtcatcgac
     8521 cgcgagatcg tgcccggcaa ctgcgtcagc accgtgagcc tcgtcctggg ctgatcgacc
     8581 ggagtcgggg cggcctccgc gcaccgcgga ggccgccccg ccctgcgtcc ggcgagcacg
     8641 acgaacaagc cgaccaacac gaccgacggg agcccccgat ggcaacgccg ctccgctcca
     8701 accgggattt ccggctgctc tggttgagcg gcctcttcgc cgtgctgggc ggccagatga
     8761 gcgccctcgc cctgcccctg ctgatcctca ggacgaccgg ctccgccgta caggccggtg
     8821 ccgtggggac ggtctccgtc tgcgccctgc tggtgacgat gctgccgggc ggggtcatgg
     8881 ccgaccgcgt cgagcgccgc cgcctgatgc ggctgtgcga cgcgggcagc ctcgccgccg
     8941 tcaccgccct gaccatcgcg gtctggtacg ggcacgcccc catggtgctc gtcctgctgg
     9001 tcgcgacctc gggagccgta ctgagcagcg tctacgcccc cgccgccttc gggctgatgc
     9061 gcgcggtcgt accgccggac cagatgggca cggccaccgc acggctccag gcgcgcaccg
     9121 ccacggtcag gatggccgga ccgctcgtcg gcggcgcgct cttcggcatc cacgaagcgc
     9181 tgcccttcgc ggcccagttc ctcggactgc tgctgtcgac gctctgcatc gccctcgtcc
     9241 gcacccgctc cgcggcccag acccgggccg gctcggtgtt cagccgccgg gaactcaccg
     9301 ccggactcac cttcctctgg caactgcctt acctccgtac ggtgttgctc gtcttcggtc
     9361 tgggcatgaa cttcgcgttc ggcgccctca ccttcaccgc gctcgccgtc ttctccgaca
     9421 acgggacctc cggcctcggc agcggcttcg tcatcacctg tgtctcggcc ggctcactcg
     9481 ccggcgcgct gctcgccccc aagatcgcac cggaccgcca tgcccgcgct ctcatcatcg
     9541 ccacctgctg gagctgcgtc ctgaccgccg cagccctggc ctggatcagc agcgcggtgc
     9601 tggccggagt gctctgcgcg ctctgcatgg cgctctcgac gatcgccagc atcggcttcc
     9661 tctcgaccct gctgatcgtc accccggagg accggatcgg gagggtgcag agcgccgccg
     9721 ggttcctgtc ctcgatcgtc cagccgttcg ggccgctcgc gggcggtctt ctgctggcca
     9781 ccctgggcac ccgctccgcc ttcggtgtca tcggctgcgt gctggccgtc tcggcggccg
     9841 tggtgacgct gtcctccgcc gtacgggccg gggcctcccc gccaccggag aagccggaga
     9901 ggccggagac gaccgaagag cccccggccc gtaccgccgc cgcagccccg cccgcccacg
     9961 acgccgccgc cggtcccggc gcactctgag gaggcacacc gtgtccgtct ccggtatcca
    10021 gcagacccag ctctactgcc tcgccgaccc cacgtactac gagaccccgg cccggctccc
    10081 ggacgagaag acccgctatc cgctggactc cgccccgccc cacgagggct ggcgccgggt
    10141 ccggggcgga ctgtggacct cgctgctgcc cgagggccgt gaactcgccg agcagggctg
    10201 gaagatccac gtctccaccg tcccggagga ggccgaggcg accctgcgcg acaccgcccg
    10261 gatctgcctc gcccacgggg tgccgttcaa gttcctccgc agcgagcagg cgctcctgct
    10321 gatgtccgac aagtacatgg cccgctccgg cgcggggaag ttcctcacgc tctacccgcc
    10381 ggacgagacc gtcttcctgc gggtgctgga cgagctgacc cacgccctcg ccgggcgccg
    10441 cggcccgtac atcctcagcg atctgcggat cggcgacgcc ccggtctacg tacggtacgg
    10501 ggcgttcacc gcccgctggt gcctggacgc cgacggcgag cgggtccacg cgctgcgcca
    10561 cccctcgggc gagctggtgc ccgacgagcg gggcgtcgtc ttccgggtgc cacggtgggt
    10621 caccgtcccc gaggtgctgc gcccgcacct cgcggcccgc gccgcctccg gggacgccac
    10681 cttcccgtac accatcacgg agtccctcca gttctccaac gcgggcggga tctacctggc
    10741 ccggcaccac gagaccggcc ggcgggtggt gctccgcgag gcccggccgc actgcggtct
    10801 cgacgcggtg ggcgacgacg cggtgacccg gctgcaccgc gaacaccggg cgctgaccgc
    10861 actggccggt ctcgactgcg tgcccgaggt gtacgccgta cgacgcgtgt gggagcacca
    10921 cttcctgatc gaggagcaca tcgagggcgc caccctcctg gaggagatcg tcggccgctt
    10981 cgccctcctc cacggctcgg gcacgaccgc cgaactcgcc gcgtacaccg cctgggtgga
    11041 ctccgtgacc gagcggctca cgcaggccct ggcggcgatc cacgcgcgcg gcctgcgctt
    11101 cggcgacctc cacccgtcca acgtcatcat ccgccccgac ggccgggtgg tcctcatcga
    11161 cttcgagtac gccaccgccc tcgacgacca ggacaccccg gtcgcgggcg cgcccggcct
    11221 ccaggcgccc acggggaccc ccggcgccga ggccgacgcc tacgcgctct gggcgacctg
    11281 gctctccatg ctgatgccgc tgatggagat ggccgggcac gaccgggcca aggccctcac
    11341 cctggagcgg tgggcccggc agcggtacgg cctggcgtcc gacgcgggac ccctgcggcc
    11401 cgccgcgctg gtggcggcgg agagccgctt cggcggcgag agcgagatcg ccgcgctgct
    11461 ggaggggccc gcccccgact gggcggagct gcgggcccgg ctgatcgcgg gcatccacgc
    11521 cggggcgacc cccgagcgca ccgaccgcct cttccccggc gacccggccg ccttcgcgac
    11581 cggcgggatc gatgtcgccc acggtgcggc cggggtgctg cacgccctgc accgcgtcgg
    11641 ggcccccgtg gagccggcct ggaccgactg gctcgccgaa gccgccctgc gccgcgaccc
    11701 cgccgccccc ggcggcctct acgacgggct gccgggcacg gcggtcgtgc tgtcgttgct
    11761 gggccggcgg gaggagggcc gggaactctt cgaacgggcc accgccgcgc ccccgtccgc
    11821 ctcggccgac ctgagatccg gccgcgcggg catcgcgctc gccgccctgc gcctggcccg
    11881 gccggccggc gaggggggcg cggcgccgga ccccgacgcc aaggtcgacc aggagctggt
    11941 ggagatagcc gtacggaccg ccgacgacct ggaccgcctg gtgcgcgggg attccgtacc
    12001 gggcctggcc gtccccgcgt cggcggggct gctgcgcggg ctgagcggcg cggccctgct
    12061 ccacctcgaa ctgcacgccc tgaccggcga ggaccggttc ctgcgggccg ccggccgggc
    12121 cctggagcgg gaggccgggc actgcgtgac gatgccgggc ggcaccgtcc aggtgaagga
    12181 cgggcggcgc cacttcctct acctggacca ggggagcggc ggcgtcgcgc tggtggccca
    12241 ggcgtatctg gcccgccgcc ccgcaccggc gctctcggcc ctgctgcccg gggtgcggca
    12301 gggctgcgtc ctcgaattcg tccgcgagcc gggcctgttc accggtcggg caggactcat
    12361 ggccacggcg ggccagctgt cgccgcagag ccgtacggaa cccgacgtcc tggcctccgc
    12421 ccgcaacctc tcctggcacc tgatcgccca ggaggaccgg ctgctggtcc cgggatcacg
    12481 gctgcggcgc tgctccgccg acctggcgac gggcgcggcg ggactgctgc tggccctgca
    12541 cttcctgtca gaggcctccg gccccggcct gctggagctg ctcaccctgg gctgaaccgg
    12601 ccctcctcgc gctcgcgcgc gtacagacag agcagccgcg gcacttcgta cagcgcggcg
    12661 tgggcggtga cctccccggc cggcgaggtc accgccccgg cgtcgatcag cgactcgacg
    12721 gtacggatcg cggcccgctc cccgcacccc agcgcctcca tcgccccgtc cagggtgaag
    12781 ccgccctcct gcgcgggccc ggccagccgc cccagcgccc gccggtcgtc cgccgacagg
    12841 tcctgccacc cggacgccat gcgcagccgt acggagatgt ccccggcgac cagctcgtcc
    12901 agggcggccg acggatcgcc gagccggtcc gcgtactccg ccagcggcag atggcgcagg
    12961 accgccagcc gcatcccgcc cacccccacc gccaacggca gcgcgccgca ggcccggacg
    13021 atccgcaggg ccgccgccgg atcggtccgc agccgcccgg gcccgatcag cttgcccagc
    13081 agctccagcg cctcgccgtc cgccagggcg cccagcgcga tccggtgcac gggggccagc
    13141 cccgccagct gcccgcgcgc ggtgagcacc accgaggacg gcccggaccg ggggagcagc
    13201 ccccgtacga aggcctcgtc cggtacgtcg tcgaggacga tcagcgcccg gtgcagcgac
    13261 agccaccgct gccaggcgtc ggccgccccc tgcgaaacgg caggcaccgt cgcatcagcc
    13321 ggcaccgcag aatcagccgc tacggccgac gcagccgtta cggccgactc cgccgggacc
    13381 cccgaaccgc ccggcgcccg caccccgcac aaccgcccga gttcgcccag gacttcggcg
    13441 ggggtgcggg ccgagccgtc ctcccgccgg acctggacgt ggaaccgccc gtccgggaag
    13501 ccgtcgccga gcaggtgggc cgcccgcagg gccagcgccg actttccgga acccacgggc
    13561 ccggacacga ccaccacccg ctcgtccggt gagcccagca gcgccagcag ctcccgcagc
    13621 tcctcgcggc ggccggtgaa gtccctcggc gcggcgggca gcgccgtacc gtacgcggcc
    13681 tcccggccgg ccgccgcggg ccgggcggta cggccccggc ccagcatcgc ccggtacagg
    13741 gccgccatcg ccggactcgg ctccaggccc aactcccgcg ccaacagctg ccggtagtcg
    13801 tcgtagaccg ccagcgcctc ggcctgccgc cccgactggt gcagcgagtt catccaggcc
    13861 acccgcaacc gctcccgcag cgggtggcgc tccaccagat cccgcaggcc gtccaccgcg
    13921 acggcggccc ggccgagctc gatctcggtc tcggcccagt cctcgtacac ggtcagacag
    13981 cgggcctcca gccgctcggc ctcctccgcg accccggtgg agtcccgcag gtcgttcagc
    14041 ggcggcccct cccacagatc gagcgcctcc cgcagcagcc gggccgccgt ccgcaggtcg
    14101 ccgcgctcac cggcggcccg cccggcgcgg gccagggagc ggaagcgcag ggtgtccagc
    14161 tcgccctcgc cgatggtgag ccggtagccg ccgcagccgt ggaccacccg gtcccggccg
    14221 tcgcggctgt ccgagccgag cagggcgcgg gcggcgctca cgtacacctg gaggttcttg
    14281 cgcgcggtgc ggggagggtc gtcgggccac accgcgtccg tcaacacgtc cacggggacg
    14341 ggggtgttgg ggcgggcgag cagggtggcc aggaccaggc gctgtttgcg cgggccgagc
    14401 gggagcgggc ggccgtcccg tacggcggtg agcgggccga gcagcgagaa gtacaccgta
    14461 ccggcggggg ccgggcgggc gggaggtcgg atcatcagcg ggcctccgga agcggggacg
    14521 ggcggcagac tgccgtacgt ttccgatcct gccgccgtca cgccccgcgc acatcggggg
    14581 actgcccgta tgttccgccc gcacacccga ccgaaagcgc cccgtgcccc catgttgtag
    14641 ggcacgcccg tgcccccgtt tccaggggca cggcccccgg ccccctcagg ccggctccgc
    14701 cgcgcactcc gccgcgaact cgcacagcgc cgagcggtcc gcccgcccgg tcttgctgag
    14761 caggctggcc atgtgcttct ccaccgtgcg tggcgatatc gacagccgcc gggcgatctg
    14821 ctggttgccc ggccgctccg ggagcagcac gaacacctcg tactcgcgcg gggtcacccc
    14881 gctggtccgc agcggcagcg ggatgcggtc ccagccgccc cggtgctggg tgacgctcgc
    14941 ccccgcctgc cgcagcgccg cccggcacgc ggaggcgacc gcctgcgccc cgaccccgta
    15001 gaagaactcc tcggaccgcc gcagccagga caccggctcg ccccacccgt cggcgccggc
    15061 cgcgtccgcg accaggcgca gcccgaggtg gcgggcgacc gggaagggca cggcccgggc
    15121 gtcgaaggag gccaccaggc ggtccgctcc ggccgggtcg ccctcccggc ccagcagcac
    15181 cgcctccgcc agctccagga actgcccgtt ccacgcgagt tgggccccgg gggaggcgcg
    15241 tacggcgtcg aactccgccc ggtccgccgc ccccgcgagc acccgcagga aggggcgcag
    15301 cccgtaactc ccgctcaggt agaagtagct ggggtggtcc tgctcccagg ccagcaccgc
    15361 gtcgagcccc gcgagcgccc gctcccggtc ctcctccagc agcgcgccga tcgccttgca
    15421 cagccccaac tggtgcggca cgagcagcga cggctcaccg cccgcccgcc ggaacgcggc
    15481 cagcgcacgg tccatgtccc gccgccgccc ccggtgcgcg gccatcgtgg cggtggagag
    15541 gagcagatag cggtgggcgg agaggttgcc gacccgggca ctggcctcca gcgaacggtc
    15601 gatgatctcc tgcgcctcgt cccaacgggc gcacagcacc gcgttcatgg cgagcagccc
    15661 gtccaccgtc tgcgtcagca gcagcgcgcc cagctcgatg gccgcggccc gcgccgagcg
    15721 cagccgggag gcgtccccgg tccgcatgaa ggcattggcg cccagccgca ccagagcctc
    15781 cacccgccag acgggcagcc cgtgatcggt ggagagcgcc agcatccgct ccaggcaggc
    15841 gtccgcctcg tcgaacccct tctcacgcag cagcagcgcc agcaactgcc aggcctggca
    15901 ggcgacgacg ggcagccctt cggcctcggc gatctcagcg gcctcgcggg cggcccgctc
    15961 ggtctccccg gggcgccggt gctcctgccc gggcagcagg gcgagatggg cgtcggcgac
    16021 ggtgagcgcg gcatggcggc cgggcgccgg atcctggccc agcagggtgc gggcggcctc
    16081 gatctggcgg gccgcgtcgg ccgcccgctc ggccatcacg gccacccagg cgatcttgat
    16141 gtggacctcg ccgcgccgct cggcggcctc ggtgcgcgcc ggaaccggcg gcagcgactc
    16201 ggccagctcc agcgcggcgt ccaggtcgcc gccctccgcc cgggcgaccg ccagggactc
    16261 ggagatcgcg gcccggtcgg cgtcggcggc cagcggacag gcccgctcca gcagcaccac
    16321 ggccgaaccg tgggcccccg aggcgagcat ccgccgtccg gcctccgcga accgcagggc
    16381 cgcgcccgca cggttgcccg cggccaggtg cagggaggcg acgagctgct gcccgtcctc
    16441 gtcgagcggg tgaccggagt gctcgatggc cccggcggcg cggcgggcga gcgaggcgcg
    16501 ctcggccggg gcgagcgagg agatcagggc ctcggcggtg agggagtggc ggaaggcgta
    16561 ccggtcgggg gcggcgccgt cgggggcgat cacgcccgcc tcgacggcgg accgcagatg
    16621 ggtgaagagg gcccggtcct cgaaaccggt gacggtctgg aggacggaga ccgagaactg
    16681 gccacccagg gtggccgccg cgagtaacag gtcccggacc ggctcgtcca gccggtcgag
    16741 tcttcgggtc caggtccgca cgatgcccga ggggaccggc ccgccgggct gctcggccgc
    16801 ctcccagccg ctccccgtcc ggcgcaactg gccggtgtcc agcagatccg cgagcagcac
    16861 ctcgaccaag tacgggttgc cacccgcccg ttcggccagc cggtggtgca ccacctgggg
    16921 tatctcctcg ggcgccgcct ccagacacgc tgcggtcagg gtccgcatct gctcgtcggc
    16981 cagcggcttc aactcccgta cggaggcggc ctggcggcgc tcggcggacc gtacgagatc
    17041 gagcgcggcc cccgcctcgg ggcgcagcgt gcccaggagc aggatcggca ggtcggcgag
    17101 gttgtcgatg acgtactcga ccaccgcgac ggtctccgtg tcgctgtcgt ggaggtcctc
    17161 cagcaggatc gcgcagccgg actcgcggcc cagcacggac aacagccgca gcagcgcctc
    17221 cgccagctcg acgaccgtct ccggatagcc gggggaggcc tcctggcgcc actcggggac
    17281 cagccgggcc agggcgggat ggtacggggc gagctcggga tcggtcgggg tgccggcggc
    17341 ccggaagcgg gaggagagcg cctccacgag tggccggaaa gggacgacga gcccggtcga
    17401 ggtggcccgg ccgcgcagca cgggcatgcc gaggccgtag gcccggtagg cggcttcacc
    17461 caccagccgg gatttcccga tcccggcctc gccgaggaag aacaaggcgc gccctgaacg
    17521 ccgttgcacg gcgtccaggg cgctgctcag caggccgatc tcctcgtccc gcccgacgat
    17581 gaccggcgat gtggctcgca tgggcgcagg ctacttgagt cgtaactcat gcgggagtgg
    17641 cccaatgcgc cacaatacgg gccgaagcgt ggtttagagc gggatcatcg tggtccacgg
    17701 caggtcgatc gtgttgccgg tctcgccctc cgaggcgctg aggagtctgc tgcgcatccc
    17761 cagcccgccg ccgatgccga gggagatctg cccggccggg tggtcgtacg cgccctcgtg
    17821 ggcgaggttg ccggagccct ggatcgcgga ttcgctgatg tgcgtcatct ctgcctcatt
    17881 ctctgctggg tgctgaatcc tgaacggaat gaacgctgga ccaaaagttt ctgacggtga
    17941 atcggctaag ggtgagaagg gtgagggggc ccgcagccgg ccgcgggagg gcctctcatg
    18001 cgacccccga tgaggggttg aggagcagcg cggagccgat ccggtcgggg aatcccgccc
    18061 gcaacagtcc gtgcccgatc cccgagaggc cggtgagcag ccccgggtgc ggtacgtggc
    18121 cgggggtccc gcagcgcggc ccctcccggt cggcggcggc cagcagcgtc ccggcccggc
    18181 gcacccacgg ggtgcggtcg ccggtcaggg ccgggtggcc gagcagttcc agcagcccga
    18241 gctcgccgtg gcagaggctg tcgtcggcga gcggggcgca gtccgccagc tctccggccc
    18301 gctccgccag ccagccggac aggtcggggt cgacgagggc gtccgagctg tccgcgaccg
    18361 cgagggccac cccggcggcc ccctcgcacc aggcccggcc cgccgtcacc tcgacggtcg
    18421 cccggcgcag ggcccgcagt cccgccgtac ggtactgctc accgcccccc gccgcggcga
    18481 agcgcagcag cgcccagccg atgcccgcgg ccccctcggc gaagcccccg gccgccgggt
    18541 gcggcgccac ggagatccgc tcggcgcagc gctcggcgcc ccgccaggcc tcggcccggc
    18601 cggtggtgcg gtgcaccgcg agcagggaga ccagcccgcc ggccgccccg ccgcgcaccc
    18661 cgtacccctc ctcggcgacg ctcgccgcgc aggccagccg ggtggccggg cccgccaggt
    18721 cgagcaccgt acggtcgccg agcagcgaac ccacctcggc cagggcgtac gcgatgccgc
    18781 cgaggcccgc gaaggccccc gagcccagca ccgcgaggtc gtcggcccgg ccgtgcagcg
    18841 cgtccagcag cccgggcacc ggggtcagcg cctcacgggc ggcctcggcg taccggtcgg
    18901 cgccggtgag ggcggccagc tgggcgagga agagcgcggg gccggtgtag ccgctcgcga
    18961 ggtcggccgc catcggcgcg agccgccagt agcgttcgcc gagcagttcc aggccgatcc
    19021 agttggtgcg ggcctcgtgc cggtaggcga gcgagacgag ctggtcgccc accgaccgtg
    19081 cggcggacag gagttgctcc ggctcggggg ccgtcgcggc catccggggc cgcgcgccgc
    19141 cctccgcccg gtgcgggagt tcgggggagg tggacaccat ggcggcccgg atgatccgtt
    19201 cctggtcctg gcggtccacc gtgtccatgg cccgcacctt cgcctcgacc cgggccaggc
    19261 cggtgggccc cggtgtgggc ggtacctcac gcccggtgcc gctccacagg tccggggagc
    19321 cgggccgggt gaggaagacc ggcacatcgc ccgcccacag ctcctcgatc tcctcgtcct
    19381 ccagaccggg cagcgcgggc acgcccaggg cgggggtgcg cagcagggag aggacctggt
    19441 ggcgttcggc ggcgtcccgc atcaggtcgg ggtgggtcga ctcgtcgagc agggtggtgt
    19501 aggtccaggt cggccggggc acgacccgta cctcgtcctg cgcgaagtcc gtcaacaggc
    19561 cgcgcttgcc gagcagatcg tcgcggtggt cgctgatggc ggtgtatccg gcgcggaacc
    19621 cttcgcacag ggcgtcggtg tacgcggacg gatcggccgg gaccccttcc agccggggcc
    19681 ggttggcgga ctcggtgaac cgcgcggagc gccgtaccag ccgcatggtg tccgtgcccg
    19741 cgtccgccca gtcggcggtc tcgatggggg agggggcggc ccggccgccg ccgatggcgg
    19801 agacgtcgag cgcggcggcg tcgccgacca gcagctgggg cagcagcccg acccggtgga
    19861 ccgaggcgtg cagggcacgg gcggcggggt cggaggagtg cgcctgggag agcggcggat
    19921 ggaacagggt ctccacatcg accaggaccg ggtgcggccc gcaggcgatc aggttctcct
    19981 ggtgcagatc ggtcccgtcc agcaggtgga gcagggccag cagcgcgccc tggcgccggt
    20041 agaagagatg ggtgtccgag gcggacgagc agggccgctc ctccacgtac tccacccacc
    20101 cgtactcacc ccggtccagc acccgcagcg cccgcaggga cggcgtcccg ggcagcgaac
    20161 cgaaccattc caccagggag ttgaagtggc ggtgcgccgc cggcgggcgc ggcttgtaga
    20221 ccagccggct cccgtcggtg aaccgcagca gcatcaccga gcggcccccg cggtgactgt
    20281 cccccgcccc ggcctcgacc ccggtcagcg cccccggccc ccgcccggcg gcgagcgtcc
    20341 ccggcgaggc accgtgcccc cggtcgccca gcacaccgga ggaggccagc agctcccggt
    20401 cgtcggcgag ccgcccgagc atctcggtga aggcgtcggc ggcggccagg ctcgcccggg
    20461 ccaggatgcg ggccagtacg ggataggcgg tgaggaaggc cgcgagcccg tcccgccccg
    20521 ccgtccgccg cacgaagtcc cggaaccgct cctgcggccc ctccccggcc agccgccctg
    20581 cccgccgcgc cttgtgcagc tccagcacga gcgtccgcgc cgcgagccgg gccagccggc
    20641 cgaccagatg ggaccggaag tcctccagta cgggggcgag cccgacggcg gtcccggccc
    20701 gtacggcgtt gttcgacggc gaggtgagca gccgcccggc ggcccgctcg gcgaacgggg
    20761 ccacgacgag ggcgaatccg gagagccccg ggtactcccg cccggcgacg acagcctcgg
    20821 ccggcgcgtc ggcgatgacg gcccggacga agacgaccca gtcgggctcc cccatgggcg
    20881 gctccccgac gactccggga agccaccagg ggttggcgcg gggggtggtg ggggcggggg
    20941 tgctgctgcc ggtgttcgta cgcgggtggt tcgcgttggc gtgatccgcg tacgggtggt
    21001 ccatgtcggc gtggtccatg tgcgcgtggt ccgtgttcgt gttgttcggg tggcccgtgt
    21061 tccggtggtc cgtgcgagcc gctccggcgg tggtgaccgc cgcttggggg gacgcggagg
    21121 gcgcggcgga cgtggaggtc ccgttcgcga cggcggcccc gacagatccg gcgggccggg
    21181 cggacccgtt cgcgccggcg gacccgtggg tgcccgggag ggcgagacgg gcagcagccc
    21241 ccgtaccgcc gctgccgatc agttccttct ccaccgcacc tcccaggtcg ggagcggccc
    21301 accggaccgc tcacgaacca tcctggcggg gggactccca gggcgcatgg gggagttgcc
    21361 cccatctttc gcccccgacc ggtggggtgg gtgggtgccg ggctcacctc gggggaccgc
    21421 accccaggtg acctggccct ggacgacccc tcacgccagg ggcgccccaa gggcacccca
    21481 gcggcacccg ggcggcctca ccccacccgg ggcggagccg tcgacccccg gatcatcaac
    21541 tcggcggcga tggtggcgat tccgccgggc ggcgggttct ccttgcccat ggcgagccgg
    21601 cccgcccgcg cgcccgcctc gaagagcggc agccgtacgg tcgtcagagc gggtacggcg
    21661 tccaccgaga acggcaggtc gtcgaagccc gccaccgaga tgtcctgcgg gatgcgcagc
    21721 ccctggtccc gtacggcggc gcaagcgccc agcgccacgg tgtcgttggc ggcgacgacg
    21781 gcggtcacgg ccgggtcccg gcgcagtatt tcgagggtgg cctcgtaccc cgagcgccgg
    21841 tcgtagggcc cgtgcacggt gagccgctcc tcgtccccgg cctccgcgtc gtcgagcccg
    21901 gcgccccgca gggcctcgcg gtggccctcc agccggtgcc gggtggtggt gcgttcgggg
    21961 ggcccggcga cgtaaccgat ccggcggtgg ccgagcgaga tcaggtgctc ggtcaaccgc
    22021 cgcccgccgc cccggttgtc gaaggcgagc gcggcgacga gcgcgtcccc ctcggggagc
    22081 gggggccgcc cgcagaagac gatccgggtg ccggcgtccg ccatcttggc gagcttcgcg
    22141 gccatcgccg cctggtgttc cgggtactcg accgcgcctc cggtgaggac gacggcggcg
    22201 gcgcgctggc gctggaggag ggtgaggtag gtgagctcgc gctcggggga accgcctgtg
    22261 ttgcagatga cggccagctt ctcgccgccc gcccgcccgg agccgtcccc gggcccgccg
    22321 atctgggtct gcgcggcccc cgccatgatc ccgaagaagg ggtcggcgat gtcgttgacc
    22381 aggatcccga ccaggtcgga ggtggcggcg gccagcgagc tggcgggccc gttgagcacg
    22441 tagtccaggt cgtccaccgc acgcaggacc cgctcccggg tcgaggcggc gaccgggtag
    22501 ttgccgttca gcacacggga gacggtggcc ggggacaccc gggcgcgggc cgccacgtcc
    22561 gccagggtga ctgtcatcgc tttcctccgt gaggtcacgt gcggcgcccc tcttgtccgg
    22621 ccgctgtccg caggctagcg tcatctcgta tagaaagcgc ttgctacggc tgtatggagg
    22681 gaacttcgtg acacgcagga cagtgcgcat cgccatgaac ggcgtcacgg gtcgcatggg
    22741 ataccggcaa catctggtgc gttcgatcct cgcgatccgc gagcagggcg gcctggacct
    22801 gggcgacggc gaggtgctct ggccggagcc cgtcctcgtc ggccgccgca cccacgccct
    22861 ggaggagctg gcggcccggc acgggctgac cgagtggtcg acggacctgg acgcggtgct
    22921 cgcggacgac acgatcgaca tctacttcga cgcccaggtc acctcggccc gggtggaggc
    22981 gatcaagaag gccatcgccg ccggcaagca catctatacg gagaagccca cggccacgga
    23041 cgtcgagggc gccctcgacc tggcccgcct cgcccgggac gcgggcatca agcacggcgt
    23101 ggtccaggac aagatcttcc tgccgggcct gctgaagctg aagcgcctga tcgacggcgg
    23161 cttcttcggc gaaatcctct ccattcgggg ggagttcggc tactgggtct tcgagggcga
    23221 ctggcaggag gcccaacgcc cctcgtggaa ctaccgaacc gaggacggcg gcggcatcgt
    23281 cgtggacatg ttcccgcact gggagtacgt gctccacgag ctgttcggtc aggtcacctc
    23341 cgtaacggcg catgtgcaga cgcacgttcc gcagcgctgg gacgagcacg gcaagccgta
    23401 cgaggcgacc gccgacgacg cggcgtacgg aatcttccag ctggcgggcg gggcggtcgc
    23461 gcagatcaac tcctcctgga cggtgcgggt caaccgggac gagctggtgg agttccaggt
    23521 ggacggtacg cacggctcgg cggtggcggg cctgcgcaac tgccgcgtac agcaccgctc
    23581 ttcgaccccg aagccggtct ggaacccgga cctgccggtc acggagtcgt tccgcgacca
    23641 gtggcaggag atcccggaca accaggagtt cgccaacggc ttcaaggcgc agtgggagct
    23701 gttcctgcgc catgtggcgc tggacgagcc gtacacgtgg gacctgctgg ccggtgcgcg
    23761 aggcgtccaa ctcgctgaac tgggactgaa atcgtcggcg gagggtcgcc gcttcgaggt
    23821 cccggagctg acgctgtgac ggcgaccgtc gccctgccct ggggcccgta caccccgcgc
    23881 gcgaccccac tggacctgcc acccccgacc gggctcccgc cgacctcccg tacggtcttc
    23941 tcggcggccc acgtggtcgc ggacccgtat gcggacatca gcccggacga cccggcggcc
    24001 gtcgactggg agtccacgct cgccttccgc cgccatctct ggtcgcacgg gctgggcgtc
    24061 gcggaggcga tggacacggc ccagcgcggg atgggcctgg actgggcggg agcggccgag
    24121 ctgatccgcc gctcggcggc ggaggcgaag gcggtgggcg ggaggatcgc ctgcggagtc
    24181 ggcacggacc agctacggcc gtcggccgag ccgacgttgg cggaggtcag gtcggcgtac
    24241 gaggagcagt tggccctggc cgaggcgaac ggcgtacaac cgatcctgat ggcgtcccgc
    24301 gccctggcga aggcggcacg gggcccggag gactacctcg ccacgtacgc ccaccttctg
    24361 cgccagtcgg gggagccggt gatcctgcac tggctgggcc cgatgttcga cccggcgctg
    24421 gagggctact ggggcagcgc cgacctggac gaggccacgg acacgttcct gagggtgatc
    24481 gccgaacacc cggacaaggt cgacggcatc aagatctcgc tcctggacgc ggcccgcgag
    24541 atcgacgtac gacgccgcct cccgagcggg gtgcgctgct acacgggcga cgacttcaac
    24601 tacccggtgc tgatcgcggg agacgaacgc ggcttcagcc acgcgctgtt gggcatcttc
    24661 gacccgctgg gcccgctggc ggctcacgcg gtacgggtgc tggacacggg agatgcggca
    24721 ggcttccggg ccctcctgga ccccacggtc gaactctccc gccacctttt ccggcccccc
    24781 acacgcttct acaagacggg cgtggtcttc ctggcctggc tggccggcca ccaggaccac
    24841 ttcacgatgg tgggcggatc gcagtcggcg cgctcgctgc cgcacctggc gaaggcgtac
    24901 gaactggcgg acggcttggg cttgttcccg gacccggacc tggcggcaca ccgtatgcgg
    24961 gcgctgctga cggtcagcgg aggcgcacga tgaacggcga acacctggcc cgcctctcgc
    25021 tcaaccagga gaccatcaag cagtggtcgc tgcccgagct ggcggagggg tgcgtcaagg
    25081 cggggatcgg caaggtcggc ctgtggcggg cgccggtcca ggcgtacggc gtggaccgca
    25141 cggcacggct tctcgcggac gccgggctga cggtcaccag cctctgccgg ggcggcttcc
    25201 tcaccgccct ggacccggcg gaccgggccg ccgccctgga cgacaaccgc cgggcgatcg
    25261 acgaggcggc ggccctctcc acgggcaccc tggtcctggt ctccggcggc ctcccgcccg
    25321 gcagccggga cctgtacggg gcgcgggagc gggtgggcga cgcgctggcc gaactcgcgc
    25381 cgtacgcggc ggggcgcggc gtacgcctgg cgatcgaacc gctgcacccg atgttcgcgt
    25441 cggaccgctg cgtggtctcc accctcgccc aggccttgga cctcgcggaa cgctttccgg
    25501 ccgagcaggt cggggtggtc gtcgacacgt accacgtctg gtgggacgac cgggcgcccg
    25561 agcagatcgc ccgcgccggg gcgggcggcc gcatccactc cttccagctg gccgactgga
    25621 tcaccccgct cccggcgggg gttctgctgg gccggggcca actgggcgac ggcagcgtgg
    25681 acttccgcgc gtggcgtacg gaagttgagg cggcgggctt cgacggcccg atcgaggtgg
    25741 agatcttcaa cgagacgctg tggacccggg acggggccga agtcctggcg gaggtcgcgg
    25801 agcgctacgt gcaacatgcc tgctgagagc cctcatcaag gaccaaggta aagagatcgt
    25861 aaagggctgc aacctttgcg taccctcccg ggtcacacat ggcgtcggga cttccgggga
    25921 ggggtccggg gggaacggga aggcccgacg gggggaaagc gaggggggtc cggccgcaag
    25981 gccgggcccc attcttgctt ttcggtgagc ggaccggagg ctgggggccg ggggccgccc
    26041 ggcgaacacc ggacggcccc cgatcacagc acggccgccc ggctcacagc acggcccccc
    26101 ggctcacagc gcgagcatga cccgcgacgc ggggataccg gcgtccgcga gcggccgcag
    26161 cgccagccgt atcagcgcca gagcgttgtc atcgcccgcg atgcggttgg cgctgagttc
    26221 gtcgcaggtc agacagaggt ggatgagcat ccactccccg tcagcccgca cggacaggct
    26281 cagcgccgtc atccgcccgc cgcaccccgc cgcccggtca cccggcaccc gccggtcgac
    26341 gtgcaggctg accaggcagg acgggcagtg gttgcgatgg gcggtgcccg gcgcgaccag
    26401 cgagacatcg agccggcagc cgacgcaccg gaacgcgtcg ccgcgcgccc cgacgggccc
    26461 gtgaagcacg tccttaggac gctgaggacg acgcgccccg cccgatcggg ctccacgccg
    26521 cgtcacaggt caccgaacgc ttcgagcggg aacggcggct gagccagtgg acgtacggcc
    26581 atccgcatca ggatgagctg gttgtcgtcc ccgcagacgg ggttcgaggt cagctcgtcg
    26641 cagcggacgc agcggtggac gaccatccag tcaccggtac ggagcaccgc gatggagatc
    26701 ggggtcatcc ggccctcgca gtcggagggc ccgccctcga cgtggtcgac gaggtgctgg
    26761 gagtgcaggc aactggggca gtggttgcgc cggctgccgt cgggcgcgaa cgcggcgacg
    26821 gtcaggccgc agcggacgca ggtgaaggtg gagagggagg acatggctga gcggtgctgg
    26881 gggtggtcgt gtgacacccg gatactcctt gccgaaggtg aggaacaaag cagcagggaa
    26941 gtaccgagca cccctcgcgg cggaaggccg gagcgtcgga ggccgtggga gaagggctgt
    27001 aggccgtgga gcgtcagcag acggtgaacg tacggctgcg caggcggtca ggcccggtca
    27061 ccccggcgtc gtgggcgcga cgagggaggc tcggagtcac tgaccggggc atacatcaac
    27121 tgctttccag ggcacacggc ccagaggtca cctgcggtcg gcaccgcgac aaggcggaag
    27181 caccgtaaca acgggaaagg aagccggacc accgaattac ggaacacaga aacaggagta
    27241 cgcccatgcc acagaccccc acgaccccca cgacccccgc cacccccagg cgctggctca
    27301 cgctcctgct gctgctagcc ctctgctacg gcgtcgccgc cgccggagcg gtcgcgacag
    27361 gtgacgcggg cagcacgtat gccgccctgg accggccggc ctgggcgcca cccgggtggc
    27421 tcttcggccc ggtgtggacg gtgctgtacg ggatgatcgc ggtggcgggc tggctggtcg
    27481 cccgccgccc cggcccgggc cgccggccgg cgctggtggc gtggggcgta cagctggcgc
    27541 tgaacgcgct gtggacgccg ctgttcttcg ccgccgaaca gtacgggctg gccttcctgg
    27601 acatcgccct cctgctggcg gcggtggtga ccaccgcgct gctctgcgcc cgggtggacc
    27661 gtcgcgcggc ctggctgctg gtgccgtatc tgctgtgggt gggttacgcg gcggcgctga
    27721 acctggcgct ctggctgacc aactgaccaa ctgacctcca tggccggaag aggcttaata
    27781 cgtcgacaga gcctggggcg cccggcagag tgtccgcccg tgacgagcag cgaacgatgg
    27841 acccgcgcga ccgccgaccg ctacgacgcc gaggagaccg agaactcctc ggccgccgtc
    27901 ctccacccca ccctcgactt ccttgccgag ctggccggag acggccgcgc cctggagttc
    27961 gccatcggga cgggccgcgt gggcgtcccg ctccgggaac gcggcgtacc ggtggtgggc
    28021 atcgaactgt ccgagcacat ggcggcggtg ctgcgccgca aggtggacga gagcacgctc
    28081 ccggtgacca tcggggacat gacgaccacg atcgtccccg gcggattcac cctggtctac
    28141 ctcgtctaca acaccatctc gaacctgctc acacaggagg agcaggtcga atgcttccgc
    28201 aacgcggccc gccacctgga gcccggtggc cgcttcgtca tcgagctgga ggtgccgccg
    28261 ctacggtcgc ttccgccggg ccagacggcg gtgccgttcg atgtatccga gcggcatctc
    28321 ggcttcgaca cattcaacct ggtcgaccag attcaggtct cgaaccactt cacccgcgag
    28381 gccgacggcc gctaccgccg gggcaactcg cgccaccggt acgcgtggcc ggcggagctg
    28441 gacctgatgg cgaggatcgc cggcctggaa cgagaacgcc gcgtcgcgga ctgggacgga
    28501 acgccgttca cccaggactc cacgaaacac atctcggcat ggcgcaagcc gacctgacat
    28561 cgccccccgg ggacccatcc gaacgagccg cagctccgaa taaccccctg agggccacgg
    28621 caccggccct cacctgcacc gttcgggggt gcggcggcct gcacccccga acggctgcca
    28681 ccgcaccgac acactcacca ccgaaccgcg gtatcggcgg tgactgactg ggcgcccccg
    28741 gggtatccgg cgcacatggc cttcatcaag cgtgtagccc tcgcccctcg cgctgtacgg
    28801 cagctgcggc gcgtccgctc cgtgtacgcc gtagggatgg cgctctccct gctcggtctg
    28861 ctcctccagg tggagcgcga tcccggtggg aggcagacgc acctcgcggc gatgattctc
    28921 gtggcgttcg tcgccttgtt cgggctgacg gccgtccagc tgtggcgcca catgcggacc
    28981 gcccactgca gcacggcgaa gaagctgacc gcgtccgtct gaccggcgct gccgcccagc
    29041 gccgtacggc tacgagaact gctgccgccc ctgagtagtc ggctccttcc ccattcacgg
    29101 ttgagccgtc aggcctgctc ctccgggtgc caggtcagcc tgagccggcc gatcagttcg
    29161 acgaacagcg cgaagctgcg gtcgacccgg tcccgttctg cggtggcgag caggtcgagt
    29221 tggaggccgc gcgcctgcgc cacgatcatc gaggcgacca ggggcgcctg atcggccggg
    29281 cacccttcgg ccaccaccag gctctccatc agcgcgagtg agtcgtgggc ggcccgctgg
    29341 aggtggcggg agtagcgttc gggctcccgt accgccagag cgtgcacttc gaacagcagc
    29401 cggtagacgg ccatgtcgtc cgggccggtc gtggtccgcc accagcgcgt caggctggtc
    29461 aggtcgcgcg gagagtcggc gaggtccgcg gcctgcgcca gccgttgccg gaggagctcg
    29521 atcacctccg tgagcaggtt ctccttggag ccgaagtgat gcagcagcgt cccatggctc
    29581 accccgaccg cgccggccaa cggccgcatc gccaggccgc tgacgccgtg ctccaggacg
    29641 tagtcggcga cggcgccgag gagttcaggc cgccggtgct ggtaacgaac agtccgaccg
    29701 tcgatgtgct ccgcgtccac ccggccgatg gtacgcgagc ggcaagtagg ttgaccgaat
    29761 ggttgagata cttttacggt ggccggcatg agccacgaca tgggacgtct gcaccacgta
    29821 ggccacgttg tccgtgacat gggcgaggcc ctcgacctct accggcggct gggcttcact
    29881 ctggcgccgc cggcctaccc cgcgatggcc ccgagcgagg gggccgcccc ggagccgttc
    29941 ggcgcggcca acacgcaagc cgacttcccg cgcaccttcg tcgagctcgt gacctgtgtg
    30001 ccgcagggag gggccgcccg ggtccccagc gaggcgaagc tcgtccccct gcgggctccg
    30061 gccgagttgc tgccccaact ggtggaacgc atcagcagca ccagcgccac tatcgcggcg
    30121 gccctcgaac gcttcgaggg cctgcacatc ctcatgttct cgtcgcccga catcgacgtc
    30181 gccgccgcac gactgagcgc tgcccgtgtg gcgcacggcg gagtcaacac cgtccaccgt
    30241 gccgtggaga ccgccgacgg aacccgcacc gagtccgtcc gctatctgga gatcgacagc
    30301 cctgaaccag ccgtgggacc gggggcggtg gccgagggaa gggtgggggt ggtcgcagac
    30361 ctggacccgt tggtgcaggc tgcccggcag ctggaccacc ccaacggcgc cttcgacctc
    30421 gtcgaggtcg tgacgtgcgt ggcggaggcc ggcctcgacg ccatggcggc caggtaccag
    30481 gactacctcg gcagcccggc gcgggccgat gggccgtcgc ggttcttcga ccttgacggg
    30541 agccggctga cgctggtccc cgattcccac ctcgcgacga ccctgccggg cgaacacgcc
    30601 cctgccgtac ccgcgttcgt cgcctacgcg gtcgccatgc gtgatctcgc cgccacccgg
    30661 aagctgctgc gcgacaacgg attccccgtc ggccgaaccg acgcgggcga catcttcgta
    30721 cccgccgcgt ccgcgctcgg cgccgcgatc atcttccgag aggggagcca ggtacgccgc
    30781 tgaccactca gcacggcagg atgcttcggt gagcggcccg tcgcgatgca cttctcccga
    30841 tccggccctg gcatgatgcc cgtcgctccg gcctgctgga tggccctgcc cttatcccct
    30901 gcccttatcc cctgaccgcc gctgagttgc accgactcga aaaggcggcc tgcgatcacc
    30961 agaccgagca ccggctgcgg atgcgcgcgc agatcgtgca gcacgaggcg ccggcccccg
    31021 caccccgccg gcgacctcca ccacggaacc cccgcccgcg cggggaccac gcttcggact
    31081 cgacgaacag gtcgccgagg ctcggaacac ccccgcctgc gcggggacca ccagaacggg
    31141 tcggcctgct cggagctgat ctgaggacca cccccgcgtg cgcggggacc acgccgccag
    31201 ctcgccttta ccgcccttga ccaggggacc acccccgcgt gcgcggggac cacacgaccc
    31261 tcgggaagat cagc
//
