LOCUS       NZ_KB891296            22664 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces sp. ScaeMP-e10 B061DRAFT_scaffold_0.1, whole genome
            shotgun sequence.
ACCESSION   NZ_KB891296
VERSION     NZ_KB891296.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. ScaeMP-e10
  ORGANISM  Streptomyces sp. ScaeMP-e10
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1873521)
  AUTHORS   Stepanauskas,R., Sieracki,M., Masland,D., Poulton,N., Swan,B.,
            Garcia,M.M., Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C.,
            Tapia,R., Chen,A., Kyrpides,N., Mavromatis,K., Markowitz,V.,
            Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G., Pagani,I.,
            Pati,A., Goodwin,L., Nordberg,H.P., Cantor,M.N., Hua,S.X. and
            Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Improved High-Quality Draft of Streptomyces sp. ScaeMP-e10
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1873521)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
REFERENCE   3  (bases 1 to 1873521)
  AUTHORS   Stepanauskas,R., Sieracki,M., Masland,D., Poulton,N., Swan,B.,
            Garcia,M.M., Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C.,
            Tapia,R., Chen,A., Kyrpides,N., Mavromatis,K., Markowitz,V.,
            Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G., Pagani,I.,
            Pati,A., Goodwin,L., Nordberg,H.P., Cantor,M.N., Hua,S.X. and
            Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. ScaeMP-e10
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            Isolation Site                    :: Gulf of Mexico
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 03:00:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,185
            CDSs (total)                      :: 7,109
            Genes (coding)                    :: 6,996
            CDSs (with protein)               :: 6,996
            Genes (RNA)                       :: 76
            rRNAs                             :: 6, 1 (5S, 16S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 45 of 113
            Pseudo Genes (incomplete)         :: 82 of 113
            Pseudo Genes (internal stop)      :: 12 of 113
            Pseudo Genes (multiple problems)  :: 23 of 113
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:33:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 754519
            Orig. end                         :: 777183
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB891296.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405355
            Source DNA and Organism available from Cameron  Currie
            (currie@bact.wisc.edu)
            Source DNA available from Cameron  Currie (currie@bact.wisc.edu)
            Organism available from Cameron  Currie (currie@bact.wisc.edu)
            Contacts: Cameron  Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22664
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="3"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22664
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22664
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12664](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12664)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    896..910
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.11"
                     /tool="antismash"
     gene            1082..1519
                     /locus_tag="B061_RS0103385"
     CDS             1082..1519
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127370.1"
                     /locus_tag="B061_RS0103385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018510158.1"
                     /transl_table=11
                     /translation="MSLPLTRRIARTALLIAAGAAPVVGAAGAASAAELPQTPDLGGLT
                     ALDGAGLGNTVDSAAQQGTQAAGDTGGRLVGTALPAAGRTVGQTAKVAAPAVQDTAGQT
                     AGSAGEAVGGIAGAAGGGLPTDALGGGLPTGGLPLGGLPIG"
     gene            complement(1604..2698)
                     /locus_tag="B061_RS0103390"
     CDS             complement(1604..2698)
                     /EC_number="2.6.1.17"
                     /EC_number="2.6.1.79"
                     /NRPS_PKS="Domain: Aminotran_1_2 (29-363). E-value:
                     2.1e-45. Score: 147.4. Matches aSDomain:
                     nrpspksdomains_B061_RS0103390_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984558.1"
                     /locus_tag="B061_RS0103390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional succinyldiaminopimelate
                     transaminase/glutamate-prephenate aminotransferase"
                     /protein_id="WP_018510159.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.8e-44, bitscore:
                     147.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVSSRLPVFPWDRLTPYKTTAQAHPDGIVDLSVGTPVDPVPEV
                     IRRALVAAADSPGYPTVWGTEALRDALTGWVEGRLGAVGVTHANVLPVVGSKELVAWLP
                     TQLGLGPGDKVAYPRLAYPTYEVGARLCGAEPVVYDDPTELDPAGLKLLWLNSPSNPTG
                     KVLSKDELTRIVAWAREHGVLVFSDECYLELGWDAEPVSVLHPDVCGGHYDGIVAVHSL
                     SKRSNLAGYRAAFIAGDAAVLGELLLIRKHGGMMTAAPVQAATVAALGDDVHVAEQRAR
                     YADRRLALRAALEAHGFRIEHSEASLYLWATRDEPCWDTVAYLAQLGILVAPGDFYGPA
                     GERFVRVAFTATDERVAAAVKRLS"
     aSDomain        complement(1610..2611)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B061_RS0103390_Aminotran_1_2.1"
                     /evalue="2.10E-45"
                     /label="B061_RS0103390_Aminotran_1_2.1"
                     /locus_tag="B061_RS0103390"
                     /protein_end="363"
                     /protein_start="29"
                     /score="147.4"
                     /tool="antismash"
                     /translation="IVDLSVGTPVDPVPEVIRRALVAAADSPGYPTVWGTEALRDALTG
                     WVEGRLGAVGVTHANVLPVVGSKELVAWLPTQLGLGPGDKVAYPRLAYPTYEVGARLCG
                     AEPVVYDDPTELDPAGLKLLWLNSPSNPTGKVLSKDELTRIVAWAREHGVLVFSDECYL
                     ELGWDAEPVSVLHPDVCGGHYDGIVAVHSLSKRSNLAGYRAAFIAGDAAVLGELLLIRK
                     HGGMMTAAPVQAATVAALGDDVHVAEQRARYADRRLALRAALEAHGFRIEHSEASLYLW
                     ATRDEPCWDTVAYLAQLGILVAPGDFYGPAGERFVRVAFTATDERVAAAVKRL"
     gene            complement(2813..3133)
                     /gene="fdxA"
                     /locus_tag="B061_RS0103395"
     CDS             complement(2813..3133)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950253.1"
                     /locus_tag="B061_RS0103395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferredoxin"
                     /protein_id="WP_003966501.1"
                     /transl_table=11
                     /translation="MTYVIAQPCVDVKDKACIEECPVDCIYEGQRSLYIHPDECVDCGA
                     CEPVCPVEAIFYEDDTPEEWKDYYKANVEFFDDLGSPGGASKLGLIERDHAFVAGLPPQ
                     NQ"
     gene            3251..4288
                     /locus_tag="B061_RS0103400"
     CDS             3251..4288
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061638.1"
                     /locus_tag="B061_RS0103400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_018510160.1"
                     /transl_table=11
                     /translation="MEFTMGGRLEVRITPADVGKRVSVRRRSAGGGAGVEFTDTVGVLT
                     SWDDGVVAITPKSGESVHIVESALVAGKVVPAAPARRRGPAASFAELATVTARAWQPVE
                     SEPLGEWRLRAAGGFTRRANSALPLGDPGLPLGEAFGRVERWYEERGLPPYIQTATGAE
                     GTQEALCAELERHGWRREVTAEVRIAALAPVGDLDADVSAVRLSRAPDEAWLSRYQRFS
                     TPGPHVLRVLGGGPSVWFATVAGAGDGAAGGGTGGEADGDAPAAIGRCVVDGRWAGFMA
                     VEVAPEHRRRGLATSVMAALARQALEEGASAAWLQVEEDNEGARALYDGMGFAAHHRYH
                     HFRPA"
     gene            4357..5238
                     /locus_tag="B061_RS0103405"
     CDS             4357..5238
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956285.1"
                     /locus_tag="B061_RS0103405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="WP_018510161.1"
                     /transl_table=11
                     /translation="MSAQDSGTADRRRQFADEARSERPDLALLCLLVGAEAGPVGPEEP
                     RPVDPAETSPDPYGIDAAQIELDRLAGLLPYGARSPVAWASALAELLGERNEFGGSSAD
                     YQRLESSLLQQVLRRRRGLPILLSVVWIEVARRAGAPVFGVALPGHFVVGFGDPAQPVL
                     VDPFTGGGPLTGQDADLLVTAATGAPLEPSMLTPARPLEIVLRILNNIRAWAAARPERT
                     DVALWAVELSLLLPSHPARLRYERAQLLVQRGEFQRGAAEMEEYAEVLDAIEPTTAEAI
                     RHKAQAARALLN"
     misc_feature    5342..5355
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.91"
                     /tool="antismash"
     misc_feature    5392..5406
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.65"
                     /tool="antismash"
     misc_feature    5393..5405
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            5453..6070
                     /locus_tag="B061_RS0103410"
     CDS             5453..6070
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127364.1"
                     /locus_tag="B061_RS0103410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_018510162.1"
                     /transl_table=11
                     /translation="MTTVLLVHTVPLWRASLASLLGAGQGIDVTTADRGAIRSALAGIG
                     PGPGPDVLLTDLDCPDALDVLEEVRSLAEPHGRGCPLAVLTRSDRPRGLRRAYEAGARG
                     YIDKYRPVDDLTEVMHKLADGGRHIDESLAFSLLQVADMPLSPRELSVLSLAEGGETVS
                     GIAQRLHLTPGTVRNYLAAAIRKSGARNRVDAIRRAKEAGWI"
     misc_feature    5864..5866
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5885..5887
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6039..7907)
                     /locus_tag="B061_RS0103415"
     CDS             complement(6039..7907)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611155.1"
                     /locus_tag="B061_RS0103415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_018510163.1"
                     /transl_table=11
                     /translation="MKAPHTAPDTARRNGALTRVTRDARPFLRARTGTVLRLAGWSLLE
                     FVQTFLGGFGVARALDHGFLAGRPLTGLLWLAVAAVAVLPAQLATRGVFGRLADLVEPL
                     RDGLVRRAVSRALSGALAHPAGTTARSLSQVTHQSEIARDGWAGLVLTLRSFVFTVAGA
                     VAGLLALEPRLLLIVLPPLILGAALFLATLLPMAARQRDYLTADEAYAAHAGRAAADLR
                     DLAAAGAADRTVAESEALAEDQVRAARSLARWSGVRVVALAVCGRFPPLLLLLGAPWLL
                     RNGLTPGALVGALTYLTQALAPAVQALMTMLSTVGGRLLVVLDRFTDAPPPPAEDESDS
                     QGPPPRDHAPVAELRAVTFAYGPAAHPVLDRLSLSVAPGEHLAVVGPSGSGKSTLAAVL
                     TGVEAPTGGTVLWHGRPVRGADATSVRVLLPQHAYVFTGSLRDNLRYLRPDASDRSIAA
                     MIDALGLDPLLSRLGSLDAPLEPDRLSQGERQLVALGRAYLAAPPLTVLDEATSRLDPA
                     AETRAERAFAALPGALVVVAHRLSSARRADRILVMDGPRTRCGTSAELLRTSALYRDLA
                     GLWEPDEEPRRENGEPDQEPHKSGRQEPHKSGRGDGLISTPPPSLF"
     gene            complement(7904..9664)
                     /locus_tag="B061_RS0103420"
     CDS             complement(7904..9664)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611154.1"
                     /locus_tag="B061_RS0103420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_018510164.1"
                     /transl_table=11
                     /translation="MRLKPRPPTPSGTRRLARRHPAALLALFLCSTGGALAALALPAAL
                     GHTVDGLIDGGPVPWSGLLLCAVLTLAETGFDAGAAVLGTSTTARLTAHLRTRTTARVL
                     AAEARDALAVPTGDLTARLTARTADAAAAPVTAAGAVAGVLLPLGAVTGLFLIDPWTAA
                     AFLLGAPLLVVLLHTFTRRTADAGADYQRAQSVIAHRLTEALDGADTIRAARTGAREYR
                     RILEPLGALADHGRRTWTVYGRAAGQSALLLPLLMLLVLAVGGIRLHAGAIGVGDLVAA
                     SRYAALAVGIGALTGALGALARSRAAARTLDPLLTLDPLPHEGLGPLPGGPGHLEFRDV
                     GVVQDGKRLLTEVHLTVPGGTSLAVVGRSGSGKSVFAAVAGRLLDPDTGTVLLDGVPLT
                     AMDPALLRPEIAYAFARPALPGTTVGDTIAFGPWTADPEAVRAAARAARADGFIGLLPY
                     GYATPLADAPLSGGERQRLGLARAFAHPGRLLILDDALSGLDTVTEHHVRRALDERAGR
                     CTRVIVAHRLSSAARADRVLWLEDGRVRATGPHEELWADPEYRAVFRTETAEEAETGAL
                     PPPRTEVEAR"
     gene            complement(9800..9931)
                     /locus_tag="B061_RS0103425"
     CDS             complement(9800..9931)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611153.1"
                     /locus_tag="B061_RS0103425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_018510165.1"
                     /transl_table=11
                     /translation="MALLDLQAMETPAEEAFGELATGSQVSLLVCEFSSLSVVLCTP"
     CDS_motif       complement(9866..9931)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQAMETPAEEAFGELAT"
                     /locus_tag="B061_RS0103425_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9800..9865)
                     /prepeptide="core"
                     /locus_tag="B061_RS0103425_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="32.40"
                     /molecular_weight="2060.4"
                     /monoisotopic_mass="2059.1"
                     /core_sequence="GSQVSLLVCEFSSLSVVLCTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQAMETPAEEAFGELAT"
                     /leader_location="[9865:9931](-)"
                     /alternative_weights="2078.4"
                     /alternative_weights="2096.4"
                     /alternative_weights="2114.5"
                     /alternative_weights="2132.5"
     gene            complement(10001..12664)
                     /gene="lanKC"
                     /locus_tag="B061_RS0103430"
     CDS             complement(10001..12664)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611152.1"
                     /locus_tag="B061_RS0103430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_018510166.1"
                     /sec_met_domain="micKC (E-value: 1.9e-229, bitscore: 760.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 4e-11, bitscore: 39.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.7e-07, bitscore:
                     24.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPEYAAYCQADRRFYDAPHRSLQDGAEEGSFYAPVRGAAPQGWT
                     RSRRGDWLSFSPDGLRLPAQGWKIHISAAADNAESVLERVAGHCLAHRLPFKCVPSPGL
                     LNLRNAKYADRAGSGKFITVYPHSEDTFPEVCAALMKLLEGEHGPYILSDLRCGNGPVH
                     TRYGAFAARFCTGPDGRPVPAVADPQGRLVPDDRGPAFRIPAWVTPPGFLRPHLEARAA
                     VGLGDVPYTVEKALHFSNGGGVYLGRDTRTGEQVVLKEARPYAGLAADGADAVARLERE
                     RTALEQLAGLDCVPAVHDAFEVGGHHFLVLQYLPGTTLNTVFARRFPLARQNPAPELLA
                     EHASWAEELYGKVERAVEAVHGRGIVISDLHMSNVMVDEETSRIFLLDFEAASPAGDRR
                     RQIVANPAFVAPSDRRGTEIDRYALACLRLALYLPLTTLFGIDRSKAAGLAREIARVFP
                     VTEESLRPAVEEIRRGAEPAARRGAEPAAVPVPDPGDWPESRAAMARAIAASCTPDRED
                     RCFPGDIAQFATATGGQSFAYGAAGVLYALHETGAPRCEPAEEWLVRQAKDPASGSPLG
                     FYDGLTGIAWTLHRTGRTAEAADLIRIVLDQPLEGLTPGLHSGYAGIGLALDDLARTAS
                     AAEAPALAAAAGRATALAVRALVDGPPSPRTGLLHGATGIALLLVRRYETTGDPALLDL
                     AAAALRRDLDRCRAGDDGELLVVEGKRLMPYLGAGSAGIAAVIDAYLAHRPDPDLEAKG
                     RALLPAALSAFYVQPGLLRGSAGLLMHLAATPLCDEETRQRAIRLHTHLLAGHALAYEG
                     GLAFAGEQLMRMSMDLATGTAGCLLALGSALDTAPGPPTTLPFLAAAPQAVAAAAPQAA
                     HPGRASGPTDRLLQGS"
     misc_feature    12698..12710
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     misc_feature    complement(12702..12716)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.56"
                     /tool="antismash"
     gene            complement(12959..13936)
                     /locus_tag="B061_RS0103435"
     CDS             complement(12959..13936)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611151.1"
                     /locus_tag="B061_RS0103435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_018510167.1"
                     /transl_table=11
                     /translation="MGWWQISTDTLATSRFVVSPLAETVASLRTLERAVAAHPRERAWL
                     ERWLPAYRRRRAEEPLSARIVRAALTPRWSADFLTPAPVPPPAGQEPDTFAQELARVRA
                     TPPERARADLAVALRRPLPAALDRDDLAGRSADVLEWVWTRAVAPEWPARRRVLEADVI
                     ARAAQLSRGGWAQALDGMRPGMRWLGESRLQINTYDNPPRELGGAQLVFTPVTADVGWV
                     CWDIPHRYGVVYPCAGALADTGRASVPQALGALIGPARAGVLVLLASPLSTTQLVALTG
                     QGLGSVGRHLRVLLDAGLVRRRRDGRSVLYFRTAAGDGLVRAAG"
     gene            14043..15305
                     /locus_tag="B061_RS0103440"
     CDS             14043..15305
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127359.1"
                     /locus_tag="B061_RS0103440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_018510168.1"
                     /transl_table=11
                     /translation="MRTYRELFRTPEFLPFFTTVSVQVAAQTASGLALGTLVYASTGSP
                     LLSALAMFGPSLAQVAGALTLLSAADRLPPRATLTGLALLYALGTGVQAVPGLPLGTAF
                     AVLLALGVASSLGGGVRYGLLNEILPRHGFLLGRSVLNMSVGTMQIAGFAVGGVLVTAL
                     SARGTLLVGAGLYVVAAALARFGLTARPPRATGRASVRETWRTNALLWSSAPRRSVYLA
                     LWVPNGLVVGCESLYVAYAPGHAGLLFACGALGMLAGDTLVGRFVPGRWRARLGAPLRL
                     LLAAPYLLFALDPGVPVAVVAVVLASVGFSASLLLQERLMALTPEELSGHALGLSSSGM
                     LAMQGVGAAVAGSVAQLTSPGTGMAAVAALSLAVTVALAPGLRAGRGQEAAAGRLQGDG
                     SPDGSPDAPPRTKETKETKIS"
     gene            15383..15949
                     /locus_tag="B061_RS0103445"
     CDS             15383..15949
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956278.1"
                     /locus_tag="B061_RS0103445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar O-acetyltransferase"
                     /protein_id="WP_043184473.1"
                     /sec_met_domain="Mac (E-value: 1.6e-13, bitscore: 47.4,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAGELYLADDPEIAADALRSALLNERFNATSAGDPEARRAALAE
                     LLGELGEGAEIRPPLRVDYGHQITVGPRTFVNFGAVFLDVARITIGADVQMGPNVQLLT
                     PTHPIDPEPRRAKWEAAQPITIGDNVWLGGGAIVCPGVSIGENTVVGAGAVVTKDLPAN
                     VVAVGNPARVIRKIGEGAEVGPGAS"
     gene            complement(16005..16550)
                     /locus_tag="B061_RS0103450"
     CDS             complement(16005..16550)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446870.1"
                     /locus_tag="B061_RS0103450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4265 domain-containing protein"
                     /protein_id="WP_018510170.1"
                     /transl_table=11
                     /translation="MSSPDAGPPRPSRDERPSRDERPSPDAGRRIKVWFRFVPREDGLP
                     YETEGLWATRVSADTARLDNVPFLQDGVAEGETVRFTTDADGVHWSAGRVADSGNCTVR
                     VLPLPDGPLGRDARAVHERLAPFELGGEVFSADFPLVAFTVPGGADLRAIKELLVRGEE
                     EGWWHFEVSCATEAWGEA"
     misc_feature    complement(16768..16785)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.97"
                     /tool="antismash"
     gene            16871..18679
                     /locus_tag="B061_RS0103455"
     CDS             16871..18679
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379170.1"
                     /locus_tag="B061_RS0103455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_026241131.1"
                     /transl_table=11
                     /translation="MHAPPTAPGTAPRSAPRRHRRSRALGFAALAVSLLMAVPTAQTAF
                     GEEVQGDRKAQGGGDLGPNVHVFDPSTPDIQGKVDEIFKKQESAQFGLDRYALLFKPGT
                     YDNINAQIGFYTSIAGLGLNPNDTTFNGDVTVDAGWFDGNATQNFWRSAENLTLNPVSG
                     TNRWAVSQAAPFRRMHVKGGLNLAPDGYGWASGGYIADSKIDGQVGPYSQQQWYTRDSS
                     VGGWGNGVWNMTFSGVEGAPANSFPEPPYTTLDTTPISREKPFLYLDGDDYKVFVPEKR
                     ENARGTSWANGTPAGESIPLDRFYVVKEGADAATINAAVEQGLHLLFTPGVYHIDETIT
                     IDRPDTVALGIGLATIIPDNGVTAIKVGDVSGVKLAGLLVDAGPVNSETLIEVGPKDAS
                     ADHAANPTSLQDVFVRIGGAGPGKATTSIVVNSDDVIIDHTWVWRADHGEGWGWETNRA
                     DYGVRVNGDDVLATGLFVEHFNKYDVEWYGERGRTIFFQNEKAYDAPNQEAIQNGDTKG
                     FAAYRVDDSVNQHEGWGMGSYCYYNVDPTIVQGHGFKAPVKPGVKFHSLIVVSLGGNGQ
                     YEHVINETGSPTSGTETIPSQVVNFP"
     gene            complement(19058..19396)
                     /locus_tag="B061_RS0103460"
     CDS             complement(19058..19396)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510172.1"
                     /locus_tag="B061_RS0103460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_018510172.1"
                     /transl_table=11
                     /translation="MSAERKAADAVDWDDLKGEFGLSEGETHEVDRRAALLLSEVRAHR
                     LAEVRKRQRMTQAAVAKVLGVTQGRVSAIEKGAINRSEVETLAAYVAALGGQLKLVADF
                     GDETLVLG"
     misc_feature    complement(19373..19382)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(19403..>19657)
                     /locus_tag="B061_RS36080"
                     /pseudo=""
     CDS             complement(19403..>19657)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019762571.1"
                     /locus_tag="B061_RS36080"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /pseudo=""
                     /transl_table=11
                     /translation="LQIEGPALGRPLVDRITGSALANLEELRPGSSGSSEVRSLFVFDP
                     ARNAVILVGGDKSGGWSGWYRTAIKAAEDAYEAYRGAKK"
     gene            complement(19788..22004)
                     /locus_tag="B061_RS0103470"
     CDS             complement(19788..22004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611145.1"
                     /locus_tag="B061_RS0103470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_026241132.1"
                     /transl_table=11
                     /translation="MSRETDSSSSGPQGRGGAAYPSGTPPYGSRQYSSPAGSDETPESV
                     DPPRPEEPKTETTLTTRIRINIPGSRPIPPVVMRTPMAESDIATGRPDAERTGSTPRPG
                     TPPSAPSGLTAGASAGTGASGGPASPSPAQPRDGGSSTEPSSASASADEPAKAKSGSDW
                     FAPRKSPAPAPAPASGAGGAPGSGGAPGAGPAGPGGGSDAAGRPRPDLPYFSDAAPRPG
                     DGPSPSGSGFPGPGGSGSALDGYSTEPPGAGPRSTPDPGIRTPGSPGTPGPSGPTTGPV
                     TGTSALTPNLDGVPGLGGPGPMVPGAPGGGPPRLSDDTAILTPQSPAPDSGPGGHVSGD
                     TLTSGIPVVPSEPRSTFPGRPGGPGGPGGPFPGGPFPGGPGATGGSGDPFADGPGGPGG
                     PGAPGPGRSAARPAPTPPAPAPAKKGRSKLVLLGVAAIVLLGIAYGAGLLLNHSEVPKG
                     TTVLGVDIGGGTKEEAVTKLDAALGERSQAPLTLSVDGKEQKLDPAKAGLVLDSQETVR
                     GAAGSDYNPVSVIGSLFGGARTADPVIPVDEEKLGVALTDLAGVAGSSQDGTIRFEPNK
                     AVAVPGKPGKTLDVGQSLISVRDAYRAQVQTGQARVVELPVATREPTITQAELTRAMKE
                     FAEPAMSDLITIKAGPKQIQFGPARSLPQILSMKAVDGRLVDVYDKEAITTLLDGVFDG
                     IEAVKADGTKHPVGADDVAQAMKTALAGKTPAERTVTINLTGEG"
ORIGIN
        1 cgcgctgtgt ggtccgggcc cccgaggggg accacaccta cgagatgagc ctgcaccagg
       61 cggcgaacgc ggcgacgatc tccgccgtgg ggaccacccg cgggatgccg gagcgggcgg
      121 tgaccatcgc gatcgcgacg gcgatccagg agtccacgct ccgcaacatc gattacgggg
      181 accgggactc ggtgggcctg ttccagcagc ggccctcgca gggctggggc accgtggcgg
      241 agatcatgga cccggtgtac tcggccgggg agttctacga ccacctcgcc gaggtgccgg
      301 gctactcgcg gctcccgctg accgtggcgg cgcagcgtgt gcagcgcagc ggcttcccgc
      361 aggcgtacgc gaagcacgag ccggacgccg cactgctggc cgccgcgctg accgggcgcg
      421 agcccgcctc gctgaactgc acgccgccga agaggaccgc cgggaacccg ggggacgcgg
      481 cgcaggtgcg ggccgagctg atccgcacct tcggcaagga cgtcctgccc gccaccaggg
      541 cggcgggcgc gtcggccgcc gccaccgtct cggtgcccgt accggcgtcg gcgcgggccg
      601 aggcggagga ccgcgctccg cagcgcggct gggagctggc gcactgggcg gtggcgcact
      661 ccgacgagct gctgatcgag cgcgtgagct atgccgaccg ggtctgggaa gccggttccg
      721 gctggcggac ggaacgtacg aaggaccagg aaccggacac caccgccgtc ggaatccggg
      781 tcgcccagta gttcggcccg tcacccgtac ggaccctgga gcctgccgct ccggggttcc
      841 cgggccacct cttcgccggt ccgttcatcc cgcatcgatt cccttgccgt tgaagggaag
      901 tgacggttca tcgaacggct tcggaatgga tcgtttgccc gggttcctcc actgcgggat
      961 tatcggacgc attacttact ctttaccttt gctcaccgca actttccctc ccctcggccc
     1021 tgttgtcagt gcgtccggct caccggatcc ggatcactga ccatcccgtc gaaggagcac
     1081 catgtccctc cccctgaccc gtcggatcgc tcgtaccgcg ctgctgatcg ccgcgggtgc
     1141 ggcccccgtg gtcggtgcgg ccggcgccgc gagcgccgca gagctcccgc agaccccgga
     1201 cctcggcggt ctgaccgcgc tggacggtgc cggtctcggc aacaccgtgg acagcgccgc
     1261 ccagcagggc acccaggccg ccggtgacac cggcggccgt ctcgtcggca ccgccctccc
     1321 ggccgcgggc cggaccgtcg gccagaccgc caaggtcgcc gcccccgccg tccaggacac
     1381 cgcgggccag accgcgggca gcgcgggcga ggccgtcggc ggcatcgccg gtgccgccgg
     1441 cggcggcctg ccgaccgacg cgctcggcgg cggcctgccc accggtggcc tgccgctggg
     1501 cggtctgccg atcggctgac ccaccgccgt acgccgtaca tgcgtgaggg cccggggagt
     1561 gcgcactccc cgggccctca cgtacgtacc gggccgtatc aggtcaggac aggcgcttga
     1621 ccgccgccgc cacccgctcg tcggtcgcgg tgaacgccac ccggacgaag cgctcgcccg
     1681 ccgggccgta gaagtcgccg ggcgccacca ggatgcccag ctgggcgagg tacgccacgg
     1741 tgtcccagca gggctcgtcg cgggtcgccc agaggtagag gctcgcctcg ctgtgctcga
     1801 tgcggaagcc gtgcgcctcc agggcggcgc gcagggccag ccggcggtcc gcgtaccggg
     1861 cgcgctgctc ggccacgtgc acgtcgtcgc cgagggcggc gacggtggcg gcctggacgg
     1921 gcgcggccgt catcatcccg ccgtgcttgc ggatcagcag cagctcaccg aggacggccg
     1981 cgtcgcccgc gatgaaggcg gcgcgatagc cggccaggtt ggagcgcttg gagagcgagt
     2041 ggacggccac gatgccgtcg tagtggccgc cgcagacgtc cgggtggagc acggagaccg
     2101 gctcggcgtc ccagcccagc tccaggtagc actcgtcgct gaagacgagg acgccgtgct
     2161 cgcgggccca ggcgacgatc cgggtcagct cgtccttgga cagcaccttg ccggtcgggt
     2221 tggacggcga gttgagccag agcagcttca gccctgccgg gtccagctcg gtcgggtcgt
     2281 cgtagacgac gggctccgcg ccgcagagcc gggcgccgac ctcgtacgtc gggtaggcga
     2341 gccgcgggta ggcgaccttg tcgcccgggc cgagcccgag ctgcgtcggc agccaggcca
     2401 ccagctcctt ggagccgacg accggcagca cgttggcgtg ggtcaccccg accgcgccga
     2461 ggcggccctc cacccagccg gtgagcgcgt cgcgcagggc ctcggtgccc cacaccgtcg
     2521 gatagccggg gctgtcggcg gcggcgacga gcgcccgccg gatcacctcg ggcaccgggt
     2581 cgaccggcgt accgacggag aggtccacga tgccgtccgg gtgggcctgg gccgtcgtct
     2641 tgtacggcgt gagcctgtcc caggggaaga ccgggaggcg ggaggagact gcggacacgg
     2701 gactctgctt tctcgggttg ctcaggccgt tcccggccgt acggaaaacg cctcggtccc
     2761 gcacggtgac aaaccgtacg ggaccgggct gcgcacaggg tgccgctgcc gcttactggt
     2821 tctgcggcgg cagtccggcg acgaacgcgt ggtcgcgctc gatgagaccg agcttcgaag
     2881 caccacccgg ggagccgagg tcgtcgaaga actcgacgtt cgccttgtag tagtccttcc
     2941 actcctccgg agtgtcgtcc tcgtagaaga tggcctcgac cgggcagacc ggctcacagg
     3001 ctccgcagtc gacgcattcg tccgggtgga tgtacaagga ccgctggccc tcgtagatgc
     3061 agtcgacggg gcactcttcg atgcaggcct tgtccttcac gtcgacacaa ggctgcgcga
     3121 tgacgtaggt cacgctgtcg ttcctcctcg gtagggcgtt ggctctcgcg cgggagcgcg
     3181 gcgtcgtcga tgcccgcccc tagtatctcc gttctcgggc acgatccgaa caggaggggc
     3241 ggactgagct gtggaattca ccatgggcgg acggctggag gtccgcatca caccggctga
     3301 cgtgggcaaa cgcgtctccg tgcggcggcg ctccgcgggg ggcggcgcgg gcgtggagtt
     3361 caccgatacg gtcggtgttc tcacatcatg ggacgacggt gtggtggcga tcacaccgaa
     3421 gagcggggag tccgtccaca tcgtggaatc cgccttggtg gcgggcaagg tcgtccccgc
     3481 cgccccggcc cgcaggaggg gcccggcggc ctccttcgcc gagctggcga ccgtcaccgc
     3541 ccgcgcctgg cagccggtgg agagcgagcc gctgggcgag tggcggctgc gcgccgccgg
     3601 cggtttcacc cggcgcgcca actccgcgct gccgctcggc gatccgggtc tgccgctcgg
     3661 cgaggcgttc gggcgggtcg agcggtggta cgaggagcgg ggcctgcccc cgtacatcca
     3721 gacggcgacc ggggccgagg ggacgcagga ggccctctgc gcggagctgg agcggcacgg
     3781 ctggcggcgc gaggtcaccg cggaggtgcg gatcgccgcg ctggcgccgg tcggcgacct
     3841 ggacgcggat gtgtcggcgg tgcggctgag ccgtgcgccg gacgaggcgt ggctctcccg
     3901 ctaccagcgc ttctccaccc ccggcccgca tgtgctgcgg gtgctgggcg gcggcccgtc
     3961 ggtctggttc gccacggtgg cgggcgcggg cgacggggcg gccggtgggg ggaccggcgg
     4021 ggaggccgac ggggatgctc ccgcggcgat cggccggtgt gtcgtggacg ggcggtgggc
     4081 cgggttcatg gccgtcgagg tcgcccccga gcaccggcgg cgcgggctgg ccacctcggt
     4141 gatggcggcc ctggcccggc aggccctgga ggagggcgcc tcggcggcct ggctccaggt
     4201 ggaggaggac aatgaagggg cgcgggcgct gtacgacggc atggggttcg cggcgcacca
     4261 ccgctaccac cacttccggc ccgcgtagcg gagtccggac ccgccggccg ggcgggggca
     4321 gtcggcagca gggacgagca ggggcatgga tcgcatatga gcgcgcagga ttccggtacg
     4381 gccgaccgca ggcggcagtt cgccgatgag gcccggtccg agcggccgga tctggcactg
     4441 ctctgcctgc tggtgggcgc ggaggcgggc ccggtcggcc ccgaggaacc gcgcccggtc
     4501 gatccggcgg agacctcccc cgacccgtac gggatcgacg cggcgcagat cgagctggac
     4561 cggctggccg ggctgctgcc ctacggcgcc cgctcccccg tcgcctgggc ctcggcgctg
     4621 gccgaactgc tcggtgagcg gaacgagttc ggcgggtcgt cggcggacta ccaacggctg
     4681 gagtcctcgc tcctccagca ggtgctgcgg cgccgccggg ggctgccgat cctgctctcg
     4741 gtggtctgga tcgaggtcgc ccggcgggcc ggcgccccgg tgttcggggt ggcgctgccc
     4801 ggccatttcg tggtcggctt cggggacccg gcacagccgg tgctcgtcga tccgttcacc
     4861 gggggcgggc cgctgaccgg ccaggacgcg gacctcctgg tcaccgcggc gacgggggcg
     4921 ccgctggagc cgtccatgct gacgcccgcg cggccgctgg agatcgtgct gcggatcctg
     4981 aacaacatca gggcctgggc cgccgcccgc cccgagcgca cggacgtcgc cctctgggcg
     5041 gtggagctct cgctgctact gccctcgcac ccggcgcgac tgcgctacga gcgggctcaa
     5101 ctcctggtcc agcgcgggga gttccagcgc ggggcggcgg agatggagga gtacgcggag
     5161 gttctcgacg ccatcgagcc gaccacggcc gaggcgatcc ggcacaaggc ccaggcggcc
     5221 cgggccctgc tgaactgagc cggatccggc cattccgcca cgccgtgcgc tcctgtttta
     5281 catccgaacg cccccatccg cgcccatcag gcacgggaat ccgccaattc gtcggcgtac
     5341 ccgaatgctc atgcgctcca ctggagaccc gtcacccgac gcgcacacgc catcgcattc
     5401 tgcgatacgc ctgtagtgcg cgcgccagga gagaaatgcc gagggcagct tgatgacaac
     5461 cgttctgctg gtccacaccg tgccgctgtg gcgcgcttcg ctggcctccc tgctcggtgc
     5521 ggggcaggga atagacgtga cgaccgccga ccggggcgcg atacgttcgg cgctcgccgg
     5581 catcgggccg ggtccaggac cggatgtgct gctcaccgac ctcgactgtc cggacgcgct
     5641 ggacgtcctg gaggaggtgc ggtcgctggc cgaaccgcac ggcaggggct gtccgctggc
     5701 ggttctcacc cgcagcgacc ggccgcgcgg gctgcgccgg gcctacgagg cgggcgcccg
     5761 cggctatatc gacaagtacc ggccggtgga cgacctcacc gaagtcatgc acaaactggc
     5821 cgacggcggg cggcatatcg acgagtcact tgccttcagc ctgttacagg tggccgacat
     5881 gcccttatct cccagggaat tgagcgtgct ctcccttgcc gagggcgggg aaaccgtctc
     5941 cggaatcgcg cagcggctgc atctgacgcc ggggacggtg cgcaattacc tcgccgccgc
     6001 cattcggaag tcgggggcgc gcaatcgggt cgacgcgatc agaagagcga aggaggcggg
     6061 gtggatatga gcccgtcccc acggccgctc ttgtggggct cctgacggcc gctcttgtgg
     6121 ggctcctggt ccggttcgcc gttctcacgg cggggctcct cgtccggttc ccagagtccg
     6181 gccaggtccc ggtagagggc cgaggtgcgc agcagctcgg cggaggtgcc gcatcgggtg
     6241 cgggggccgt ccatcaccag gatccggtcg gcgcggcggg ccgagctgag gcggtgggcg
     6301 acgaccacca gggcgcccgg cagcgcggcg aaggcacgct cggcacgggt ctcggcggcc
     6361 gggtccaggc ggctggtcgc ctcgtcgagg acggtgagcg gcggggccgc cagataggcg
     6421 cggccgaggg cgacgagctg gcgttccccc tgcgagagcc ggtccggttc caggggcgcg
     6481 tcgagcgatc cgagccggga gagcaggggg tccaggccga gcgcgtcgat catggcggcg
     6541 atggaccggt cgctcgcgtc ggggcggaga tagcggaggt tgtcgcgcag cgagccggtg
     6601 aacacgtagg cgtgctgggg cagcaggacg cgtacggagg tggcgtcggc cccgcgcacc
     6661 ggccgcccgt gccacagcac cgtgcctccg gtgggcgcct ccaccccggt gaggacggcg
     6721 gcgagcgtcg atttgccgct gccgctcggc ccgacgacgg ccaggtgctc gccgggggcg
     6781 acggagaggg agagccggtc gaggacgggg tgcgcggcgg ggccgtacgc gaaggtgacg
     6841 gcgcggagtt cggcgacggg ggcgtggtcc cgcgggggtg gtccctggct gtcgctctcg
     6901 tcctcggccg ggggcggcgg cgcgtccgtg aagcggtcca ggaccaccag cagacggccg
     6961 ccgaccgtgg agagcatggt catcagcgcc tggaccgccg gggcgagcgc ctgggtgagg
     7021 tacgtcagcg cgcccaccag ggcgccgggt gtgaggccgt tgcggagcag ccagggagcg
     7081 ccgagaagca gcaggagggg cgggaagcgc ccgcagaccg ccagcgccac cacccgtacg
     7141 ccggaccagc gggccagtga acgggccgcg cggacctggt cctcggccag ggcctcggac
     7201 tccgccaccg tgcggtcggc ggccccggcg gcggcgaggt cccgcaggtc ggcggcggcc
     7261 ctgcccgcgt gggccgcgta agcctcgtcg gcggtgaggt agtcgcgctg gcgggcggcc
     7321 atcggcagca gggtggccag gaagagggcg gcgcccagga tcagcggggg caggacgatc
     7381 agcaggagcc tcggctccag ggccagcaac cccgccaccg ccccggccac ggtgaacacg
     7441 aacgaccgca gcgtcaggac gagtccggcc cagccgtccc gggcgatctc actctgatgg
     7501 gtgacctggg agagggagcg ggcggtggtg ccggcggggt gcgcgagggc gccggagagc
     7561 gcccgggaga ccgcgcgccg cacgagaccg tcgcgcagcg gctccaccag gtccgccagg
     7621 cgtccgaaga ccccgcgggt ggcgagctgg gcggggagta cggcgacggc ggcgacggcc
     7681 agccagagga ggccggtgag cgggcgtccg gcgaggaagc cgtggtccag cgccctggcg
     7741 acgccgaatc cgcccaggaa ggtctggacg aactccagca gggaccagcc ggccagccgc
     7801 aggacggttc cggtgcgggc gcggaggaag gggcgggcgt cgcgcgtgac gcgggtgagg
     7861 gcgccgttgc ggcgggccgt gtcgggtgcc gtgtggggtg ctttcaccgg gcctccactt
     7921 ccgtacgggg cggtggcagc gcccccgtct ccgcctcctc cgccgtctcc gtacggaaca
     7981 ccgcccggta ctccggatcc gcccagagct cctcgtgcgg tcccgtcgcc cggacccggc
     8041 cgtcctccag ccagaggacc cggtccgcgc gggcggccga ggagagccgg tgggccacga
     8101 tcacgcgggt gcagcgcccg gcccgctcgt cgagggcgcg gcggacgtgg tgctcggtga
     8161 cggtgtcgag gccggagagc gcgtcgtcca ggatcagcag gcggccgggg tgggcgaacg
     8221 cgcgggccag gcccaggcgt tgccgttcgc cgccggagag cggggcgtcg gcgagcgggg
     8281 tggcgtagcc gtacgggagg agcccgatga acccgtcggc gcgggcggcc cgggcggcgg
     8341 cccgcaccgc ctcggggtcc gcggtccacg gcccgaaggc gatcgtgtcc ccgaccgtgg
     8401 tgccgggcag ggcggggcgg gcgaaggcgt aggcgatctc ggggcgcagg agggcggggt
     8461 ccatggcggt gagcgggacg ccgtccagca ggacggttcc ggtgtccggg tcgaggagcc
     8521 ggccggccac cgccgcgaac accgacttgc ccgaaccgga gcggccgacg acggcgaggg
     8581 acgtgccgcc ggggacggtg aggtggacct cggtgagcag gcgctttccg tcctggacga
     8641 cgccgacgtc ccggaattcg aggtggcccg ggccgccggg gagcgggccc agcccctcgt
     8701 gcggcagcgg gtccagggtg agcagcgggt ccagggtgcg ggcggcggcg cggctgcggg
     8761 cgagggcgcc gagggcgccg gtgagggcgc cgatgccgac ggcgagggcc gcgtaccggg
     8821 aggcggcgac gaggtcgccg acgccgatcg cgcccgcgtg gagccggatt ccgccgaccg
     8881 cgaggaccag cagcatgagg aggggcagca ggagggcgct ctggccggcg gctcgcccgt
     8941 acacggtcca ggtgcggcgg ccgtggtcgg ccagggcgcc gaggggttcg aggatgcggc
     9001 ggtactcgcg ggctccggtg cgggcggcgc ggatggtgtc ggctccgtcg agggcctcgg
     9061 tgaggcggtg ggcgatgacg gactgagcac gctggtagtc ggccccggcg tcggcggtgc
     9121 ggcgggtgaa ggtgtgcagg aggacgacga ggaggggcgc gccgagcagg aaggcggccg
     9181 ctgtccacgg gtcgatgagg aagaggccgg tgaccgcgcc gagcggcagc aggacgcccg
     9241 cgacggctcc ggctgcggtg acgggtgcgg ccgccgcgtc ggcggtgcgg gcggtgagcc
     9301 gggcggtgag gtcgccggtc ggcacggcga gggcgtcgcg cgcttcggcg gccaggaccc
     9361 gggcggtggt gcgggtgcgc aggtgggcgg tgagccgggc ggtggtgctg gtgccgagga
     9421 cggccgcgcc cgcgtcgaac ccggtctcgg cgagggtcag tacggcgcag agcagcagcc
     9481 cggaccaggg cacgggcccg ccgtcgatga gcccgtcgac ggtgtggccg agggcggcgg
     9541 gcagggcgag ggcggcgagc gcgccgccgg tggagcagag gaacagggcc aggagggcgg
     9601 cggggtggcg gcgggcgagc cgccgggtgc cggagggcgt tggtgggcgg ggcttcagcc
     9661 gcacgtggtc tccctctccg gacccgtagc gatcggtacg tacggacgcc gccggtcccg
     9721 ggcggatgaa ccgctcggga ccggcggacg ggccgcccgg cccgccggca aggtcaccgg
     9781 ccgagcgggc ggcgaggcgt cacggggtgc agaggaccac gctcagcgag ctgaactcgc
     9841 agaccagcag cgagacctgg ctgcccgtgg cgagctcgcc gaaggcctcc tcggccgggg
     9901 tctccatcgc ctgaaggtca agaagcgcca tgatggtgtt tcctttctgg gacggtaacc
     9961 ggaacccgtt gctccggctg ggtgttgagc ggtggtggtg ctacgacccc tgaaggagcc
    10021 ggtccgtggg gccgctcgcg cggccgggat gcgccgcctg tggagcggct gcggcgaccg
    10081 cctgtggagc ggcggcgagg aagggaagtg tggtgggcgg gcccggcgcg gtgtccagcg
    10141 cgctgcccag ggcgagcagg cagccggcgg tcccggtggc caggtccatc gacatccgca
    10201 tcaactgctc accggcgaag gcgagtccgc cctcgtacgc gagtgcgtgg ccggccagga
    10261 ggtgggtgtg gaggcggatc gcccgctgcc gggtctcctc gtcgcacagg ggcgtggccg
    10321 ccaggtgcat gaggagtccg gccgagccgc gcagcagtcc gggctggacg tagaaggcgg
    10381 agagcgcggc cgggagcagg gcgcggccct tggcctccag gtcgggatcg gggcggtggg
    10441 ccaggtaggc gtcgatgacg gccgcgatgc cggcgctgcc cgctccgagg tagggcatca
    10501 gccgcttgcc ctcgacgacg aggagttcgc cgtcgtcgcc cgcccggcac cggtccaggt
    10561 cgcgccggag agcggcggcg gccaggtcga ggagagcggg gtcaccggtg gtctcgtacc
    10621 ggcggaccag cagcagggcg atgccggttg caccgtgcag gaggccggtg cgcggtgacg
    10681 gcgggccgtc gaccagggcg cgtacggcga gggcggtggc ccggcccgcg gctgcggcga
    10741 gcgccggggc ttcggcggcg gaggcggtgc gggccaggtc gtcgagggcg agaccgatac
    10801 cggcataccc gctgtgcagg cccggtgtca ggccctccag gggctggtcg aggacgatgc
    10861 ggatgaggtc ggcggcctcg gcggtgcggc cggtccggtg gagcgtccag gcgatgccgg
    10921 tgaggccgtc gtagaagccg aggggggagc cggaggccgg gtccttggcc tgccgcacca
    10981 gccattcctc ggccggctcg cagcgcgggg cgccggtctc gtgcagggcg tagagcacgc
    11041 ccgccgcccc gtaggcgaag gactggccgc cggtcgccgt ggcgaactgg gcgatgtcgc
    11101 ccgggaaaca tcggtcctcg cggtcgggcg tacaggaggc ggcgatggcg cgggccatcg
    11161 cggcgcggct ctccggccag tcaccggggt cgggcaccgg cacggcagcc ggttccgcgc
    11221 cgcgccgggc agccggttcc gcaccccgcc ggatctcctc caccgccggt cgcaggctct
    11281 cctccgtcac cgggaagacg cgggcgatct cgcgcgccag accggcggcc ttcgagcggt
    11341 cgatgccgaa cagcgtggtg agcggcagat acagggcgag ccgcagacag gccagcgcgt
    11401 accggtcgat ctcggtgccg cgccggtcgg acggggccac gaaggccggg ttggcgacga
    11461 tctggcggcg ccggtcaccg gccggggagg cggcctcgaa gtcgaggagg aagatccggg
    11521 aggtctcctc gtcgaccatg acgttgctca tgtgcaggtc gctgatgacg atgccccggc
    11581 cgtggacggc ctcgacggcg cgctcgacct tcccgtacaa ctcctcggcc catgacgcgt
    11641 gttcggcgag cagttcgggg gccgggttct gccgggcgag cgggaagcgg cgggcgaaga
    11701 cggtgttgag ggtggtgccc ggaaggtact ggaggacgag gaagtggtgg ccgccgacct
    11761 cgaacgcgtc gtgcacggcc ggtacgcagt cgagtccggc cagctgctcc agcgcggtcc
    11821 gctcccgctc aagccgggcg acggcgtcgg ccccgtcggc ggcgagcccg gcgtaggggc
    11881 gggcctcctt gaggacgacc tgctcgccgg tgcgggtgtc gcggccgagg tagaccccgc
    11941 cgccgttgga gaagtgcagc gccttctcga cggtgtacgg cacatcaccg agaccgacgg
    12001 cggcgcgggc ttcgaggtgc gggcgcagga agccgggcgg cgtcacccag gcgggtatcc
    12061 ggaaggccgg gccccggtcg tcggggacca gacgcccctg cgggtcggcg acggcgggca
    12121 cgggccgccc gtcggggccc gtacagaagc gcgcggcgaa cgccccgtac cgggtgtgca
    12181 ccggaccgtt cccgcagcgc agatcgctga ggatgtacgg gccgtgctcg ccctccagca
    12241 gcttcatcag cgcggcgcac acctcgggga acgtgtcctc ggagtgcggg tagacggtga
    12301 tgaacttgcc gctccccgcc cggtccgcgt acttggcgtt ccgcaggttc aacaggccgg
    12361 gtgacgggac gcacttgaag ggcagccggt gggccagaca gtgtccggcg acccgctcca
    12421 ggacggactc ggcgttgtcg gcggcggccg atatgtggat cttccagccc tgggccggca
    12481 gccggagccc gtccgggctg aaggagagcc agtcaccgcg gcgggagcgg gtccacccct
    12541 ggggggcggc gccccggacc ggtgcgtaga acgaaccctc ctcagcgccg tcctgaaggg
    12601 aacggtgggg ggcgtcgtag aagcggcggt ccgcctggca gtacgcggcg tactccggat
    12661 tcacgacatt ccccccgctc ggtcgttgct ggcgagagag aaattgtcac aacgatgagc
    12721 agcgccaata gtcaccgatg tcatgactca tacatgcgcg cgatccatgc ggaccgcacc
    12781 gccgaccggt gatttccctg gtgcgggcag gggcgcgcgc ggggcgtgtt cagctcgcgc
    12841 cgcacaacag cccgtcccgt ccaggtacgg aatcagcctg ccgcgcacac cagtccatcc
    12901 cgtccaggtg cggaatcagc ccgccgcgcg caccagcccg tcccgtcctg gtgcggaatc
    12961 agcccgccgc gcgcaccaac ccgtcccccg cggcggtacg gaaatagagc acggaccgtc
    13021 cgtccctgcg gcggcgcacc agtcccgcgt ccagcagaac ccgcagatgg cgcccgacgg
    13081 accccagccc ctgcccggtc agcgccacga gctgggtcgt gctgagcggc gaggccagca
    13141 ggaccaggac gcccgcccgc gccggtccga tcagcgcgcc gagcgcctgc ggtacggagg
    13201 cacgcccggt gtcggcgagc gcgcccgcgc acgggtagac gacgccgtag cggtgcggga
    13261 tgtcccagca gacccagccc acgtcggcgg tgacgggggt gaacaccagc tgggcgccgc
    13321 ccagttcgcg cggcgggttg tcgtacgtgt tgatctggag ccggctctcc cccagccacc
    13381 gcatccccgg ccgcatcccg tcgagcgcct gcgcccagcc gccccggctc aactgggcgg
    13441 cccgggcgat cacatcggcc tccaggaccc ggcgccgggc gggccactcg ggcgccacgg
    13501 cacgcgtcca cacccactcc aggacatcgg cgctccgccc cgccaggtcg tcccggtcca
    13561 gcgcggcggg cagcggccgg cgcagcgcca cggcgagatc ggcgcgggcc cgctccggcg
    13621 gggtcgcccg gacccgcgcc agctcctggg cgaaggtgtc cggctcctgt ccggcgggcg
    13681 ggggcacggg ggcgggggtg aggaagtcgg cgctccagcg gggggtgagg gcggcgcgga
    13741 cgatccgggc ggagagcggt tcctcggccc gccggcgccg gtaggcgggc agccaccgct
    13801 ccagccaggc gcgctcgcgc ggatgcgcgg cgacggcccg ctccagggtg cgcaggctcg
    13861 ccaccgtctc ggccagcggt gagacgacga agcggctggt ggcgagggtg tccgtactga
    13921 tctgccacca gcccacggcc cgcccccgga tcctcagtat ttcgcctgcc cgcgaaagag
    13981 tgatgtttcg cctgcccgcg aaagaataac gagcccggag agcacccccg cacactccgc
    14041 tgatgcgcac ctaccgcgaa ctcttccgca ccccggagtt cctccccttc ttcacgaccg
    14101 tctccgtgca ggtagcggcg cagaccgcga gcggcctcgc cctcggcacc ttggtgtacg
    14161 cgtcgaccgg ctcaccgctg ctgtcggcgc tggcgatgtt cggcccgtcc ctggcgcagg
    14221 tcgccggtgc gctcaccctg ctgtcggcgg cggaccggct gccgccgcgc gccacgctga
    14281 ccggcctggc gctgctgtac gcgctgggca ccggagtgca ggcggtcccg ggcctgcccc
    14341 tggggacggc cttcgcggtc ctgctggccc tcggggtggc ctcctcgctg ggcggcgggg
    14401 tgcggtacgg gctgctcaac gagatcctgc cgcgccacgg cttcctgctc ggccgctcgg
    14461 tgctcaacat gtcggtgggc accatgcaga tcgccgggtt cgcggtgggc ggggtgctgg
    14521 tgaccgcgct ctcggcgcgc ggcacgctgc tggtgggggc ggggttgtac gtcgtcgcgg
    14581 ccgccctcgc ccgcttcggg ctcaccgccc ggccgccccg cgccaccggc cgggcctcgg
    14641 tccgggagac ctggcggacc aacgcgctcc tctggtcgtc cgcaccccgc cgctccgtct
    14701 acctcgccct gtgggtgccc aacgggctcg tggtggggtg cgagtccctg tacgtcgcct
    14761 acgcgcccgg gcacgcgggg ctcctcttcg cctgcggggc cctggggatg ctggccgggg
    14821 acacgctggt gggccggttc gtgccggggc ggtggcgcgc ccggctcggc gctccgctgc
    14881 ggctgctgct ggccgccccg tacctgctgt tcgccctgga ccccggggtg ccggtggcgg
    14941 tggtcgcggt ggtgctggcg agcgtcggat tcagcgcgag cctgctgctc caggaacggc
    15001 tgatggccct gacaccggag gagctgagcg ggcacgcgct ggggctgagc tcctccggga
    15061 tgctggcgat gcagggcgtg ggcgcggccg tcgcggggtc cgtcgcccag ctgacctcgc
    15121 cgggaaccgg gatggcggcg gtcgcggcgc tctcgctggc ggtgacggtg gccttggcgc
    15181 cggggctgcg ggcgggacgc gggcaggagg cggcggcagg cagactgcaa ggggacggat
    15241 cacccgacgg atcacccgac gcaccacccc gtacgaagga aacgaaggag acgaagatct
    15301 cgtgaccagc caggacaccc ccgactcccc caactccccc gagaacgaag cgaagaagac
    15361 gccgggcagc cagcgggagg ccatgctcgc gggcgagctc tacctcgccg acgacccgga
    15421 gatcgcggcg gacgccctgc gctcggcgct cctgaacgag cgcttcaacg ccacgtcggc
    15481 cggcgacccc gaggcccgcc gcgccgcgct ggccgagctg ctgggcgagc tgggcgaggg
    15541 cgccgagatc cgcccgccgc tgcgggtgga ctacgggcac cagatcacgg tgggcccgcg
    15601 cacgttcgtg aacttcgggg cggtgttcct ggacgtcgcc cgcatcacga tcggcgccga
    15661 cgtccagatg ggccccaacg tccagctcct caccccgacc cacccgatcg acccggaacc
    15721 gcgccgcgcc aagtgggagg cggcgcagcc gatcacgatc ggggacaacg tgtggctggg
    15781 cggcggggcg atcgtctgcc cgggggtgtc catcggggag aacacggtgg tcggggcggg
    15841 cgcggtggtc acgaaggacc tgccggcgaa tgtggtcgcg gtgggcaatc cggcccgggt
    15901 gatccggaag atcggggagg gggcggaggt ggggccgggg gcttcgtaac cgtagagctg
    15961 gagtcgtgga ccgccccgcg ccgggtccac ggccccaggg ccccctacgc ctccccccaa
    16021 gcctccgtgg cgcacgagac ctcgaagtgc caccacccct cctcctcgcc ccggacgagc
    16081 agctccttga tcgcccggag gtcggcgccg cccggcacgg tgaacgcgac cagcggaaag
    16141 tccgcgctga agacctcgcc gcccagctcg aacggggcga gccgctcgtg cacggcgcgg
    16201 gcgtcccgcc cgagcggacc gtccggcagg ggcagcaccc gtaccgtgca gttccccgag
    16261 tcggccaccc gcccggcgga ccagtgcacc ccgtccgcgt cggtcgtgaa ccgtacggtc
    16321 tcgccctcgg cgaccccgtc ctggaggaag ggcacgttgt cgaggcgggc ggtgtcggcg
    16381 ctcacccggg tcgcccacag cccctcggtc tcgtacggca gcccgtcctc gcgcgggacg
    16441 aagcggaacc agaccttgat ccgccggccg gcatcaggag acgggcgctc atcgcgtgac
    16501 gggcgctcgt ctcgggacgg gcgcggcgga ccggcgtcgg gcgagctcat ggccccatgg
    16561 tcccccttgc gccggacgcc cgctcgtccg gcgccgcgtc gccggggcca cggcacccac
    16621 acgggacatc agttcatgaa gtcaacgagc gccccaactg accgcgaaat cggtcaatcg
    16681 ccgcaccgct gacgtcagtt gttgcgaaac aggctcctcg cacgagacgc atcacgcaca
    16741 cctcttgacg cgtacaggcc caccggggaa acatcaccgt aacgagagag cgctctctcg
    16801 cattctcccc acaggcgctc tcccgcccgt ccgtcgtgca cacgtatcac gacccaggag
    16861 acgtaccttc atgcatgctc cccccaccgc accaggcacc gcaccgcgct ccgcaccccg
    16921 caggcaccgc cgctccagag ctctcgggtt cgccgcgctc gccgtatcgc tgctcatggc
    16981 cgtccccacc gcccagacag cgttcggcga agaggtccaa ggagaccgga aggcccaggg
    17041 cggcggtgac ctcgggccga acgtccatgt cttcgacccg tccacgcccg acatccaggg
    17101 caaggtcgac gagatcttca agaagcagga gtccgcgcag ttcggcctcg accgctacgc
    17161 gctgctgttc aagccgggca cgtacgacaa catcaacgcg cagatcgggt tctacacctc
    17221 gatcgcaggc ctcgggctca acccgaacga caccacgttc aacggcgatg tgacggtcga
    17281 cgcgggctgg ttcgacggca acgccacgca gaacttctgg cgctcggcgg agaacctgac
    17341 gctgaacccg gtctccggca ccaaccgctg ggccgtctcc caggccgcgc ccttccgccg
    17401 gatgcacgtc aagggcgggc tgaacctggc gcccgacgga tacggctggg ccagcggcgg
    17461 ctacatcgcg gacagcaaga tcgacggcca ggtcgggccg tactcccagc agcagtggta
    17521 cacccgcgac agctcggtgg gcggctgggg caacggcgtc tggaacatga cgttctccgg
    17581 cgtcgagggc gccccggcca acagcttccc ggagccgccg tacaccacgc tcgacaccac
    17641 ccccatctcc cgcgagaagc ccttcctcta cctggacggg gacgactaca aggtcttcgt
    17701 cccggagaag cgggagaacg cgcgcggcac gtcctgggcg aacggcacgc cggcgggcga
    17761 gtcgatcccg ctggaccggt tctacgtggt gaaggagggg gcggacgcgg cgacgatcaa
    17821 cgcggccgtg gaacagggcc tgcacctgct cttcacgccc ggcgtctacc acatcgacga
    17881 gaccatcacc atcgaccgcc ccgacacggt ggccctcggc atcggcctcg cgacgatcat
    17941 cccggacaac ggggtgacgg cgatcaaggt cggtgacgta tccggtgtga agctcgcggg
    18001 cctcctggtc gacgcgggcc cggtgaactc cgagacgctg atcgaggtcg gccccaagga
    18061 cgcctcggcc gaccacgcgg ccaaccccac ctcgctccag gacgtgttcg tacggatcgg
    18121 cggcgcgggc cccggcaagg cgaccacgag catcgtcgtc aacagcgacg acgtgatcat
    18181 cgaccacacc tgggtgtggc gcgcggacca cggtgagggc tggggctggg agaccaaccg
    18241 ggccgactac ggcgtccgcg tcaacggtga cgacgtgctg gcgaccgggc tgttcgtcga
    18301 acacttcaac aagtacgacg tggagtggta cggcgaacgc ggccgcacga tcttcttcca
    18361 gaacgagaag gcgtacgacg cccccaacca ggaggcgatc cagaacggcg acaccaaggg
    18421 tttcgcggcc taccgggtcg acgactcggt gaaccagcac gagggctggg gcatgggcag
    18481 ctactgctac tacaacgtcg acccgaccat cgtgcagggg cacggcttca aggcaccggt
    18541 gaagcccggc gtgaagttcc acagcctgat cgtggtctcg ctgggcggca acgggcagta
    18601 cgagcacgtg atcaacgaga ccggatcccc gacgtccggc acggagacca tcccctcgca
    18661 ggtggtgaac ttcccgtagt ccttttccgg ctacgggagt tgtacgggag cggggtccgg
    18721 cagctgatga gcgccgggcc ccgctccgcc gcgcctcccc tgtgccctca ggtccgtccg
    18781 taccggatgg tgtgatcggc gaactccagt gccatctcgg tggtgacggt gggccgggtg
    18841 cggctgatgg tgcgcaggaa gtcctccgtg gtgggctgcg cccgggtccc ggtgtcgagg
    18901 gtgcgctcga agacggcctg ggcgaagatg ctcttgccgg cgcccggggg ggcgaacagg
    18961 acgacggcct gcggcggttc gacatgggag cggggcgcct gtcggcgggg aacagccgcg
    19021 gcccccgccc gggggccgtc gcgggggaca ggtcaagtca tcccaggacg agggtttcgt
    19081 ctccgaagtc ggcaacgagt ttcagctgtc cgcccagtgc ggcgacatac gcggcgagag
    19141 tctcgacctc ggagcggttg atcgcgccct tctctatggc cgacacacgc ccttgggtga
    19201 cgccgagaac ctttgccact gccgcctgcg tcatccgctg gcgcttgcgc acctcggcga
    19261 gacggtgtgc cctcacctcg gacaacaaca gggcggcgcg ccgatcaacc tcatgggtct
    19321 cgccttcgga aaggccgaac tcacccttga ggtcgtccca gtcgacagcg tcggccgcct
    19381 tccgctctgc actcacggct cctcatttct tcgcacccct gtacgcctca taggcgtctt
    19441 ccgctgcctt gatcgccgtc cggtaccacc ccgaccaacc accggacttg tcgccgccca
    19501 ccaggatgac cgcgttgcgc gccgggtcga acacgaacaa gctccgtacc tcgctggagc
    19561 ctgatgaacc gggccgcagc tcttcgaggt tcgcgagagc cgaacccgtg atgcgatcga
    19621 cgagcggccg accgagggcg ggcccttcga tctgcaggac atcaccctta cgtgatatca
    19681 cccagaggta atatacgcag ggggctgcag agggtggaat aaacgaccgc ggcccccgcc
    19741 cggggtgtcc gggcgggggc cgtcgagggt gcgtgcggcc gggaggctca gccctcgccg
    19801 gtcaggttga tggtgaccgt gcgctctgcc ggggtcttgc cggccagggc cgtcttcatc
    19861 gcctgggcca cgtcgtccgc gccgaccggg tgcttggtgc cgtcggcctt gaccgcctcg
    19921 atgccgtcga agacgccgtc caggagagtg gtgatcgctt ccttgtcgta gacgtcgacc
    19981 agtcggccgt cgacggcctt catcgagagg atctgcggca gcgaacgcgc cgggccgaac
    20041 tggatctgct tcgggccggc cttgatggtg atcaggtccg acatcgcggg ctccgcgaac
    20101 tccttcatcg cccgggtcag ttcggcctgg gtgatggtgg gctcccgggt ggcgacgggc
    20161 agttcgacca cccgcgcctg accggtctgc acctgggcac ggtaggcgtc gcggacggag
    20221 atcagcgact ggccgacgtc cagggtcttg ccgggcttgc ccggcaccgc gaccgccttg
    20281 ttcggctcga accggatcgt gccgtcctgg gacgaaccgg cgacacccgc cagatcggtc
    20341 agcgcgacgc cgagcttctc ctcgtcgacc gggatcaccg ggtcggccgt gcgcgccccg
    20401 ccgaacagcg agccgatcac ggacaccggg ttgtagtcgc tgcccgcggc gccgcgcacg
    20461 gtctcctggc tgtccaggac cagaccggcc tttgccgggt ccagcttctg ctccttgccg
    20521 tccaccgaca gcgtcagcgg cgcctgggaa cgctcgccga gagcggcgtc cagcttggtg
    20581 accgcctcct ccttcgtgcc gccgccgatg tcgacgccga gcactgtggt gcccttgggg
    20641 acctcggagt ggttcagcag gagcccggcg ccgtaggcga tgccgagcaa cacgatcgcg
    20701 gccacgccga ggaggaccag cttggagcgg cccttcttcg cgggggcggg tgcgggaggc
    20761 gtcggcgcgg ggcgcgcggc ggagcggccg ggcccgggtg cacccgggcc gcccgggccg
    20821 cctggtccgt cggcgaacgg gtcgccggag ccgccggtgg cgcccgggcc gccggggaag
    20881 ggaccgcccg ggaacgggcc gccggggccg cccggaccgc ccggcctgcc cgggaacgtc
    20941 gagcggggct cgctgggcac cacggggatg ccgctggtca gcgtgtcgcc cgagacatgg
    21001 ccgccggggc cggagtcggg cgccggggac tgcggcgtga ggatcgcggt gtcgtcggag
    21061 agccggggcg gtccgccgcc gggggcgccc gggaccatcg ggccggggcc gccgagtccg
    21121 gggacgccgt cgaggttggg ggtcagggcc gaggtgccgg tgaccgggcc cgtcgttggg
    21181 ccggacgggc cgggcgtacc gggcgaaccg ggcgtacgga ttccggggtc gggcgtggag
    21241 cgcgggcccg cgccgggggg ctccgtgctg tagccgtcca gggcgctgcc ggagccgccg
    21301 gggccgggga acccggaacc ggaggggctg gggccgtcac cggggcgcgg cgcggcgtcc
    21361 gagaagtacg gcaggtcggg acgcggccgg ccggccgcgt cggacccgcc accgggaccc
    21421 gccggacccg caccgggcgc cccgccggaa cccggcgcac cgcccgcacc ggaagcaggt
    21481 gcgggcgccg gtgccgggct cttgcgcggg gcgaaccagt cgctgccgct cttcgccttg
    21541 gccggctcgt ccgcggaggc ggaggcggag gacggctcgg tggagctgcc gccgtcccgg
    21601 ggctgcgcgg gagacgggga ggccgggccg ccggacgcac cggttccggc cgacgcgccg
    21661 gccgtcaggc ccgacggcgc ggacggtggc gtgccggggc gcggggtgct gccggtgcgc
    21721 tccgcgtcgg ggcggccggt ggcgatgtcg ctctcggcca tcggcgtacg catcacgacc
    21781 ggcgggatgg gacgcgaccc ggggatgttg atccggatgc gcgtcgtcag cgtcgtctcg
    21841 gtcttcggct cttcgggccg gggcggatcg acggattccg gggtctcgtc cgagccggcc
    21901 ggcgacgaat actggcggga tccgtacggc ggcgtacccg acgggtacgc ggctccaccg
    21961 cgcccctggg gcccggagga cgaactgtca gtttcacgac tcaaagcagg ttctcccgat
    22021 tggctccgcc gcccgtactt cccccatgcc gcaggccagg ggacggctcg gcgcgcgcac
    22081 caccatactg gccgccgccg taggacactc cgcgaccggg agaaacctcc acctcggcat
    22141 cacacctgtg gggggcattc cgggcgcgga cttagcactt cagataccgg accggccgtt
    22201 acgggtggct gattgcggca ctttggaggt ggtggcgcac atcacagcga cggcggttcc
    22261 gccgagcatg aagagcacca ggccgagttc gtcgccgaag acgtagtcgc cttccggccg
    22321 gccggacagc agaaggaaca cggtgatgaa ccagccgacc gcgggcgcga gtgcgccgat
    22381 ctgggtgccg gtcaggatcc ggccgccgta gaagaggccc gccgacccgg ccagcgcgat
    22441 gatcaacccg cccgggaacc aggccgcttg gaccagcgtc ccggcgagcg cgacgagggc
    22501 gccgagcacc gcgagcccga agtaggccgc gatccgggcc gggttcggcc gggcggtgaa
    22561 gccggtggac tcgggcaccc ggggcggggc gttggtacgt ggtgcgttgc tgctgggggc
    22621 cttaccgcgc gcgccggcgc gcggccggtc ggtgcgcggc cggt
//
