LOCUS       NZ_KB890947            26574 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces sp. CcalMP-8W B053DRAFT_scaffold_6.7, whole genome
            shotgun sequence.
ACCESSION   NZ_KB890947
VERSION     NZ_KB890947.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. CcalMP-8W
  ORGANISM  Streptomyces sp. CcalMP-8W
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 366432)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
REFERENCE   2  (bases 1 to 366432)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. CcalMP-8W
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 03:14:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,603
            CDSs (total)                      :: 6,529
            Genes (coding)                    :: 6,424
            CDSs (with protein)               :: 6,424
            Genes (RNA)                       :: 74
            rRNAs                             :: 6, 1 (5S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 35 of 105
            Pseudo Genes (incomplete)         :: 83 of 105
            Pseudo Genes (internal stop)      :: 5 of 105
            Pseudo Genes (multiple problems)  :: 18 of 105
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:04:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 280609
            Orig. end                         :: 307183
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB890947.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405361
            Source DNA and Organism available from Cameron  Currie
            (currie@bact.wisc.edu)
            Source DNA available from Cameron  Currie (currie@bact.wisc.edu)
            Organism available from Cameron  Currie (currie@bact.wisc.edu)
            Contacts: Cameron  Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26574
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26574
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26574
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16574](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16574
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    22..37
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.04"
                     /tool="antismash"
     gene            complement(108..1049)
                     /locus_tag="B053_RS0128590"
     CDS             complement(108..1049)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049646.1"
                     /locus_tag="B053_RS0128590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_018492023.1"
                     /transl_table=11
                     /translation="MGAGHDHGHTHGGPPPTGTAAAAYRGRLRVALTITLSVMVMEIVG
                     GVLSDSLALIADAAHMATDALGLGMALLAIHFANRPAGPNRTFGFARAEILAALANCLL
                     LLGVGAFLIFEAVDRFITPAETKGGLAIMFAVVGLVANLVSLSLLMRGQKESLNVRGAY
                     LEVMADTLGSVAVIVSAGIIMATGWQAADPIASLVIGLMIVPRTVKLLRETLNVLLEAA
                     PKGVDMAEVRAHITALPGVLGVHDLHAWTITSGMPVLSAHVVVRQEMLDSIGHEKVLHE
                     LQGCLGDHFDVEHCTFQLEPSGHAEHEARLCH"
     misc_feature    1145..1159
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            complement(1208..2197)
                     /gene="galE"
                     /locus_tag="B053_RS0128595"
     CDS             complement(1208..2197)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (39-183). E-value:
                     9.9e-10. Score: 29.9. Matches aSDomain:
                     nrpspksdomains_B053_RS0128595_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128924.1"
                     /locus_tag="B053_RS0128595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_026238228.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 9.3e-19, bitscore:
                     61.8, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 9.6e-14,
                     bitscore: 45.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMAAAGERVVVLDDRSSGVVERLPDTV
                     TLVEGRIADRALLDRVLAEHAVSGVVHLAAKKQVGESVERPLLYYRENVAGLGVLLEAV
                     VAAGVRRFLFSSSAAVYGVPDVDLITEETPCLPINPYGETKLAGEWLVRAAGKAHGIST
                     ACLRYFNVAGAAGPELADTGVFNIVPMVFDRLTRGEAPRIFGADYPTPDGSCVRDYIHV
                     ADLAEAHLAVARKLAGREGGDLTLNVGRGEGVSVRELIDVIREVTGYPVEPVVEPRRAG
                     DAPRAVASDALMVRELGWTARRDVRSMVESAWEGWCLRHPQARPGTRR"
     aSDomain        complement(1649..2080)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B053_RS0128595_NAD_binding_4.1"
                     /evalue="9.90E-10"
                     /label="B053_RS0128595_NAD_binding_4.1"
                     /locus_tag="B053_RS0128595"
                     /protein_end="183"
                     /protein_start="39"
                     /score="29.9"
                     /tool="antismash"
                     /translation="RLPDTVTLVEGRIADRALLDRVLAEHAVSGVVHLAAKKQVGESVE
                     RPLLYYRENVAGLGVLLEAVVAAGVRRFLFSSSAAVYGVPDVDLITEETPCLPINPYGE
                     TKLAGEWLVRAAGKAHGISTACLRYFNVAGAAGPELADTG"
     CDS_motif       complement(2108..2194)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B053_RS0128595_0001"
                     /evalue="8.90E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="B053_RS0128595"
                     /protein_end="30"
                     /protein_start="1"
                     /score="28.0"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMAAAGERVVVL"
     misc_feature    complement(2260..2274)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            2517..4340
                     /locus_tag="B053_RS0128600"
     CDS             2517..4340
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955402.1"
                     /locus_tag="B053_RS0128600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_018492025.1"
                     /transl_table=11
                     /translation="MLTAADAGDAAALLAAVPAGRRVALVDPRFVGHVHALRLGLTDPR
                     FPAAAVAGALTARAEARPALVRALQRTTATVVAGTSTAVPEAGAETAPQTGEEPAADRT
                     TGRTAAGAAPEDPTLPGRTAAALEAEGTPVHRPALGSLVAAVPADAEQEAAAVAGITSV
                     DDEAVRLRSAVKAHDGFFTTFCISPYSRYIARWCARRGLTPNQVTTASLVTALVAAGAA
                     ATGTRGGYIAAGLLLLVSFVLDCTDGQLARYSLQYSTMGAWLDATFDRAKEYAFYAGLA
                     IGAVRGGDDVWTLALGAMVLQACRHVVDFSFNEANHDAVANTSPTAALSSKLDSVGWTV
                     WARRMIVLPIGERWAMIAVLTALTTPRIVFYALLVGCSLAACYTTAGRLLRSLTRKARR
                     TDRAAQALADLADSGPLAQAVAAVSPGLRGAFTVPAAALLGALVMVGSALFLPYGSRLT
                     VVAAGVYVVLSGLAVARPLKGTLDWLVPPVFRAAEYVTILVLAARSDVPHAVPAAFGLV
                     SAVAYHHYDTVYRIRGGTGAPPRWLVRTIGGHEGRTALVAVLAAVLTHASGFTTALTAL
                     AVAVALVVLVESIRFWVSSSAPAVHDEGELA"
     gene            4337..5074
                     /locus_tag="B053_RS0128605"
     CDS             4337..5074
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955403.1"
                     /locus_tag="B053_RS0128605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_018492026.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.1e-13, bitscore:
                     44.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGDKTVLDLTLANFAAV
                     GLTEVAIVVGYRKEAVYARKAELEATYGLTITLIDNDKAEEWNNAYSLWCARDVIKRGV
                     ILANGDTVHPVSVEKTLLEARGKGQKIILALDTEKTLADEEMKVIVEEGKGVQRITKLM
                     DPASATGEYIGVTLIEGEAAEELADALKTTFERDPDLYYEDGYQELANRGFTVDVAPIG
                     TVTWVEIDNHDDLKKGREIACQY"
     gene            5062..6123
                     /locus_tag="B053_RS0128610"
     CDS             5062..6123
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="B053_RS0128610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_018492027.1"
                     /sec_met_domain="Fe-ADH (E-value: 4.4e-19, bitscore: 62.7,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 6.9e-10, bitscore:
                     32.7, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRRGAMDDLAGLLADQRISSSGRLAVAISD
                     GSGRALKERLAPDLPGADWYPVSDGTIDSAVKLADGIKGNRYDAVVGLGGGKIIDVAKY
                     AAARVGLPMVAVATNLSHDGLCSPVATLDNDNGRGSYGVPTPIAVVIDLDVIREAPVRF
                     VRSGIGDAISNISCVADWELAHEVNGEEIDGLAAAMARQAGEAVLRHPGGVGDDSFLKV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLYPQRAASHGEQVGLGACFAMHLRG
                     AHQESLLMASILRRHGLPVLPEEIGFTVDEFVRAVDYAPQTRPGRFTVLEHLNLSTDQI
                     RDAYADYAKTISS"
     gene            6101..6880
                     /locus_tag="B053_RS0128615"
     CDS             6101..6880
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="B053_RS0128615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_026238229.1"
                     /transl_table=11
                     /translation="MPRPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREVSLRVDRYLV
                     NTRVTPNQVTYVMTLAAVLAAPALLVPGIPGALLGVLMVQLYLLFDCVDGELARWKKQY
                     SLSGIYLDRVAAYLCDAAVLVGLGLRAADIWGEGRTDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQGGLPPVKESASEPRSSGMALARRAAGALKFHRLILGIEASLLILLVAIVDT
                     IGGDLFYTRLATAVLAGIALLQTLLHLVSVLASSRLK"
     gene            6889..7761
                     /locus_tag="B053_RS0128620"
     CDS             6889..7761
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513265.1"
                     /locus_tag="B053_RS0128620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_018492029.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.1e-13,
                     bitscore: 45.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGAVIITMGNRPDELRALLDSVAAQDGDRIEVVVVGNGAPVPD
                     LPPGVRTVELPENLGIPGGRNIGIEAFGPSGADVDALLFLDDDGLLPDRGTAELCRRAF
                     EADPGLGILTFRITDPDTGTTQRRHVPRLRAADPLRSSRVTTFLGGANAVRTKVLAEVG
                     PLPEEFFYAHEETDLAWRALDAGWMIDYRADLVLHHPTTAPSRHTVYHRMVARNRVWLA
                     RRNLPAPLIPLYLGVWLLLTLVRRPSPPALKAWFGGFREGWSTPCGPRRPMKWRTVWRL
                     TRLGRPPVI"
     gene            7863..8792
                     /locus_tag="B053_RS0128625"
     CDS             7863..8792
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="B053_RS0128625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_018492030.1"
                     /transl_table=11
                     /translation="MSDTTHDGGVALGTPPSADEGLGPAQLAAKYGLTVSGARPGLFEY
                     VRQLWGRRHFILAFSRAKLTAQYSQAKLGQLWQVVTPLLNACVYYLIFGLILGTREGIP
                     DDVFVPFLVTGVFVFTFTQSSVMAGVRSISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSMIVLVTVAIIFGSYPSLSWLLVIPALILQFVFNTGLALIMARLGSKTPDLAQLMPFI
                     MRTWMYASGVMFSIPVMLKDKPQWIADVLQYNPAAVYMDLVRFAMIDGYGSENLPDHVW
                     AVGLGWALLLGAVGFVYFWKAEERYGRG"
     gene            8785..9570
                     /locus_tag="B053_RS0128630"
     CDS             8785..9570
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964853.1"
                     /locus_tag="B053_RS0128630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_018492031.1"
                     /transl_table=11
                     /translation="MAEDNTQGRTPTVIADDVHIVYRVNGGGGGRGSATAALSRMLRRG
                     KGEQRGVRKVHAVRGVSFTAYRGEAIGLIGTNGSGKSTLLRAIAGLLPTESGRVYTDGQ
                     PSLLGVNAALMSDLTGERNVVLGGLAMGMSQAEIRSRYQEIVDFSGINEKGDFITLPMR
                     TYSSGMAARLRFSIAAAKNHDVLMIDEALATGDHKFRVRSEARIRELRKEAGTVFLVSH
                     NNKSIRDTCDRALWLEKGELLMDGPTEEVLKAYERETGK"
     gene            10001..10912
                     /gene="hpnC"
                     /locus_tag="B053_RS0128635"
     CDS             10001..10912
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955408.1"
                     /locus_tag="B053_RS0128635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene synthase HpnC"
                     /protein_id="WP_018492032.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.1e-41,
                     bitscore: 136.4, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 6.4e-39, bitscore:
                     128.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTPQARTGDATLGKAADENFPVAPFFLPRAWRDDLMAVYGFAR
                     LVDDIGDGDLAPGGADARHLGLEPEQSDDRLAMLDALEADLHRVFAATGQEPHHPLMSA
                     LRPTVRRRALTPEPFLGLIEANRQDQKVRRYATYEELAAYCELSANPVGRLVLALTGTT
                     SPERVRRSDAVCTALQIVEHLQDVAEDLARDRIYLPAEDMDRFRVSEADLARPTAGASV
                     RALIAYESERASELLDEGIPLVGSVDGRLRILLAGFVGGGRSALTAISAAGFDVLPGPP
                     KPTKPSMLREVAVVLRRARRER"
     gene            10921..11862
                     /gene="hpnD"
                     /locus_tag="B053_RS0128640"
     CDS             10921..11862
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450952.1"
                     /locus_tag="B053_RS0128640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_032780722.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.7e-59, bitscore:
                     194.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.3e-72,
                     bitscore: 237.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGQTTHMSPPVQAAYSYCEAVTGQQARNFAYGIRLLPYEKRQAM
                     SALYAFSRRVDDIGDGELDPATKRTRLESTRELLDRIRHGKVEEDDTDPVAVALADAAR
                     RFPLPLEGLDELIDGVLMDVRSATYETWDDLKTYCRCVAGAIGRLSLGVFGTEPGAPGA
                     ERASEYADTLGLALQLTNILRDVREDAGNGRTYLPADDLAKFGCSAGFHGTTPPPGSDF
                     AGLIHFEVRRARTLFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLRGRV
                     SLPGHEKAYVAVRGLSGLDARHVSRLTSRGRA"
     gene            11981..13366
                     /gene="hpnE"
                     /locus_tag="B053_RS0128645"
     CDS             11981..13366
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072793.1"
                     /locus_tag="B053_RS0128645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_018492034.1"
                     /transl_table=11
                     /translation="MSDETPRPVAVVVGGGLAGITAALRLADAGLDVTLLEGRPRLGGL
                     AFSFQRGDLTVDNGQHVYLRCCTGYRWFLDRIDGAHLAPLQDRLDVPVLDVGRAAGPRL
                     GRIRRTGLPVPLHLAGGLAAYPHLSLAEKANVGRAALALGRLDPADPALDEIDFATWLK
                     RHGQSERTVEALWDLVGVATLNATAPNASMALAAKVFKTGLLSEPGAADIGWATVPLGE
                     LHDTLARKALDTAGVRTELRAKVGSLTRTEDGRWSVETAGERLTAETVVLAVPQHETHD
                     LLPAGALDEPDLLLDIDNAPILNVHVIYDRTVLRRPFFAAIGSPVQWVFDRTHSSGLKG
                     PGQYLAVSQSAAQDEIDLPVAELRERYLPELERLLPAARGAGIRDFFVTRERTATFAPA
                     PGTGRLRPGPRTRAAGLHLSGAWTDTGWPATMEGAVRSGSQAADAALHDLGRPQGHPLQ
                     EAA"
     gene            13363..14466
                     /locus_tag="B053_RS0128650"
     CDS             13363..14466
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964849.1"
                     /locus_tag="B053_RS0128650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_050451552.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.2e-61, bitscore:
                     200.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTTGTRGESVTPANPASDTVDQTTDVTALLERGRALSAPVLRA
                     AVDRLAPPMDTVAAYHFGWIDAEGRPADGDGGKAVRPALALLSAEAAGAPAEAGVPGAV
                     AVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALAYDLLLELGTVE
                     AGRAARRLTSATRKLIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACAVSIGAVLG
                     GADDRTADTLEAYGYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRKKSLPVVAALA
                     AGGPASERLGELLAADAKSNDFDSFSEEEFAARAALIEEAGGREWTAQEARRQHAVAIE
                     ALHGVDMPHQVRAQLTALADFVVVRKR"
     gene            14574..16574
                     /gene="shc"
                     /locus_tag="B053_RS0128655"
     CDS             14574..16574
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964848.1"
                     /locus_tag="B053_RS0128655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_018492036.1"
                     /sec_met_domain="T2TS (E-value: 2.3e-149, bitscore: 492.6,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGPAGAAELSATTAGHPDRTTLVPDEVLAAARRAAERSVE
                     HLLGRQDEQGWWKGDLATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWN
                     TFYGGPSDLSATIEAYVALRLAGDAPDAPHMARAASWIREQGGIAAARVFTRIWLALFG
                     WWKWDDLPELPPELMFLPSWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELH
                     TDPARPNPSRKLAPAASWDGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIVERQEND
                     GCWGGIQPPAVYSLIALHLLGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWD
                     TCLATIALVDGGLRPDHPALVKAADWMLAEEITRPGDWSVRKPGLAPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVRHPDPARVEAAIERGVRWNLGMQSRNGAWGAFDADNTSSFPNR
                     LPFCDFGEVIDPPSADVTGHVVEMLAVEGRARHPRTRRGIEWLLAEQEACGAWFGRWGV
                     NYVYGTGSVVPALIAAGLPAAHPSVRRAVEWLESVQNDDGGWGEDLRSYREEKWIGHGE
                     STASQTAWALLALLAAGRGDSVAVTRGVTWLTDAQQADGSWDEPYFTGTGFPWDFSINY
                     HLYRQVFPLTALGRYVYGDPFADRTGAAQDA"
     gene            16574..17227
                     /locus_tag="B053_RS0128660"
     CDS             16574..17227
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513257.1"
                     /locus_tag="B053_RS0128660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018492037.1"
                     /transl_table=11
                     /translation="MGGAPGSGSPQAPPPLLVACALGIEQVALRSGRRPAGPVRVLRTG
                     MGPRAAEAAVAAALAPGGAPEAAVIASGFCAGLAPGMHPGDLVVAEEARDADGATPCTG
                     TGLLVAALARAVPGATVHTGPLTGSDHVVRGPERAALRATGAIAVDMESAATLRTALCH
                     GPRPVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRAVLPAFYEWHRSLLLPRR"
     misc_feature    17207..17209
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17233..18252
                     /gene="hpnH"
                     /locus_tag="B053_RS0128665"
     CDS             17233..18252
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128938.1"
                     /locus_tag="B053_RS0128665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_018492038.1"
                     /sec_met_domain="PF04055 (E-value: 4.2e-18, bitscore: 60.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 9.1e-10, bitscore: 32.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLFEQKLRKREKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVARKKYVF
                     LCTNAMLMRKKLDKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAMKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLNYLNDDLKVDEMMISPAYAYEKAPDQEHFLGVDQTREL
                     FKKAFAGGNRARWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRQLIEETDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARESVGGNR"
     gene            18249..19646
                     /locus_tag="B053_RS0128670"
     CDS             18249..19646
                     /NRPS_PKS="Domain: Aminotran_3 (45-367). E-value: 4.9e-86.
                     Score: 280.7. Matches aSDomain:
                     nrpspksdomains_B053_RS0128670_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492039.1"
                     /locus_tag="B053_RS0128670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_018492039.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.9e-87, bitscore:
                     287.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDGGPQGFDLGRLLAERGGERYELHARHLNHQLPRMLHTIGFDK
                     VYERAEGAYFWDADGQDYLDMLAGFGVMGLGRHHPVVRRALHDVLDAQLADLTRFDCQP
                     LPGLLAEKLLGHSPHLDRVFFGNSGTEAVETALKFARYATGKPRVLYCDHAFHGLTTGS
                     LSVNGERGFRDGFAPLLPDTPIALGDLDGLRRELKRGDVAALVVEPVQGKGVHAAPPGF
                     LREAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVCVAKALSGGYVPVGA
                     TLGKEWIFRKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMEDEETVAGARRTGDLLR
                     GRLAALVDRYELLHEVRGRGLMIGIEFGRPSSLKLRSRWTMLQAARKGLFAQMVVVPLL
                     QKHRILTQVSGDHLEVIKLIPPLIIGEAEVDRFVAAFTEVMDDAHSGGGLMWDFGRTLV
                     KQAVANR"
     aSDomain        18384..19349
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B053_RS0128670_Aminotran_3.1"
                     /evalue="4.90E-86"
                     /label="B053_RS0128670_Aminotran_3.1"
                     /locus_tag="B053_RS0128670"
                     /protein_end="367"
                     /protein_start="45"
                     /score="280.7"
                     /tool="antismash"
                     /translation="VYERAEGAYFWDADGQDYLDMLAGFGVMGLGRHHPVVRRALHDVL
                     DAQLADLTRFDCQPLPGLLAEKLLGHSPHLDRVFFGNSGTEAVETALKFARYATGKPRV
                     LYCDHAFHGLTTGSLSVNGERGFRDGFAPLLPDTPIALGDLDGLRRELKRGDVAALVVE
                     PVQGKGVHAAPPGFLREAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVC
                     VAKALSGGYVPVGATLGKEWIFRKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMEDE
                     ETVAGARRTGDLLRGRLAALVDRYELLHEVRGRGLMIGIEF"
     misc_feature    19668..19681
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.16"
                     /tool="antismash"
     gene            19713..20321
                     /locus_tag="B053_RS0128675"
     CDS             19713..20321
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955416.1"
                     /locus_tag="B053_RS0128675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_018492040.1"
                     /transl_table=11
                     /translation="MNPQDEGAADELPGVAPRLRELRRGRGITLETAAQRAGLSPAHLS
                     RLETGRRQPSLPMLLGLARIYGTTVSELLGEKPPERDAIIRGGAFEGAEADGWMYRRAG
                     SPGRAMQALRVRVPYGAQGDLVRVHPGEEWLYVVGGRLRVALGETVHDLDPGDSAHFDS
                     LTPHRIAALDRGGAELLFVHSLLQSPAAELCLGNALHAR"
     gene            20431..20607
                     /locus_tag="B053_RS1000000137250"
     CDS             20431..20607
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019761586.1"
                     /locus_tag="B053_RS1000000137250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6126 family protein"
                     /protein_id="WP_018492041.1"
                     /transl_table=11
                     /translation="MSDSEHYDPLSPRRPRATKDAQERRMPRGLVIRLVAYLVVGHVIA
                     AFLYLLFMVAGAE"
     gene            complement(20612..21424)
                     /locus_tag="B053_RS0128685"
     CDS             complement(20612..21424)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964842.1"
                     /locus_tag="B053_RS0128685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_018492042.1"
                     /transl_table=11
                     /translation="MTQQVPQVPPTETALNGVRNFRDVGGLPTTDGRRTAFGRLYRSGH
                     LAHATAEDAAFLSGLGLHTVFDFRNSADHQLDGYDIELAGVRNVSIPLSDPADGAEFWR
                     LVRDGNIEQLRSILAGGKGTERMLHMYRATIVDRTAEHSRVLHALAEDSVPALMHCAAG
                     KDRAGLSIAVSLLAVGVEREAIEADYLKSNDPHRRYKVKRTDMSATGMSPEVMELLNPL
                     FGAQSSYLAAAFTAIDETWGSTDRYLSEGLGVSAATRERLRERLLDQG"
     misc_feature    21566..21580
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.37"
                     /tool="antismash"
     misc_feature    complement(21808..21822)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.09"
                     /tool="antismash"
     regulatory      21836..21996
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            22000..22998
                     /locus_tag="B053_RS0128690"
     CDS             22000..22998
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128943.1"
                     /locus_tag="B053_RS0128690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_018492043.1"
                     /transl_table=11
                     /translation="MPAQGKHRRPKSGPITRGVLAAGTGGAVLALPLIGATGAHAAEKA
                     APAVKPAATAAVVPAAAPQAAPAKAKTAPKTYSVVSGDYLAKIAAEHQLKGGWQKLYQD
                     NRSTVGENPGLIFPGMKLTLGAKAAGSAAPSEAKKAAPAPKSAPKTEKKAAPKAAPKKA
                     EQAPKGDTISADESDAAQKRSGATTQTGASQSTGSGWTAPLDSAQVTTQYRASGSSWSS
                     GYHTGADFRAASGTPVRAIGPGTVVSAGWSGSYGNEVVIRHADGMYSQYAHQSSLNVST
                     GQTVTGGQQIGLSGSTGNSTGPHLHFEVRTGPSYGSDVDPVAYLRQHGVSL"
     misc_feature    complement(23140..23150)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.16"
                     /tool="antismash"
     gene            23170..23997
                     /locus_tag="B053_RS0128695"
     CDS             23170..23997
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449852.1"
                     /locus_tag="B053_RS0128695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_018492044.1"
                     /transl_table=11
                     /translation="MADDSRTQQQNTIGSYAAIGDSFTEGVGDPGPDGTFVGWADRFAV
                     LLADRLPAPDAATNPDETRHGNFRYANLAVRGRLLDQIVEEQIPRAKELAPDLVSFCAG
                     GNDIIRPGTDPDDLAERYEKAVAELTEAVGSVMITTGFDTRGVPVLRHMRGKIATYNVH
                     LRAIADRYRCPVLDLWSLRSVQDRRAWDADRLHLSPEGHTRVALRAAQVLGHDVPADPD
                     QPWPPQAQRRPFDERRDNIQWAREYLVPWIGRRLRGESSGDHVEAKRPDLLPL"
     gene            complement(24024..24956)
                     /locus_tag="B053_RS0128700"
     CDS             complement(24024..24956)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378201.1"
                     /locus_tag="B053_RS0128700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="STM4011 family radical SAM protein"
                     /protein_id="WP_018492045.1"
                     /transl_table=11
                     /translation="MDLTILYRGPLASCDYDCPYCPFAKRRDSRAQLTSDREALERFTA
                     WAAAQTGDRLSVLFTPWGEGLVRSWYRRALTELSHLPHLGRVAIQTNLSGRTAWLADAD
                     PERIALWCTYHPGQTPYERFLGKCRELSARGIRFSVGVVGFEAHLEEARRLRAALPPEV
                     YLWVNAAEGRTYTDEEAARWTELDPLFPYSRHPHRSAGLPCRTGESVISVDGEGTVRRC
                     HFVKAELGNLYDGSYRRALGPRACPLAVCDCHIGYVHLETLPLYDVFAGGVLERIPAGP
                     GAGPAPDGPLVPGPTRRTLPLLNPGPLNP"
     gene            complement(24964..26346)
                     /locus_tag="B053_RS0128705"
     CDS             complement(24964..26346)
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019761593.1"
                     /locus_tag="B053_RS0128705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="STM4012 family radical SAM protein"
                     /protein_id="WP_018492046.1"
                     /sec_met_domain="PF04055 (E-value: 5.7e-15, bitscore: 50.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSTTAATGTPAVRPYESYVYAYPHKTAYRPLPERPALRELWAT
                     ERKDALSLYLHIPFCEVRCGFCNLFTRIGAPEELTTRYLDALDRQAVAVRDGLGDDEPV
                     RFAAAAFGGGTPTFLTAGELERLCDIAEKRMGADLRAVPLSVETSPSTATADRLAVLAD
                     RGTTRISIGVQSFVDAEAKAAVRPQRRAEVEAALGRIRDARIPLLNIDLIYGIDGQTER
                     TWLTSLDAALAWRPEEMYLYPLYVRPLTGLHRLGAGVSGPEAEALEQAAWDEQRLRLYA
                     VGRDHLLAHGYEQVSMRMFRRADAPQEGPEDYACQTDGMIGLGCGARSYTSALHYSFDY
                     AVDMREIRSIIDSFTATQDFSRAEVGRYVDEEEARRRHLLQSVLQAAGLPVADYRARFG
                     TDPWADFPAELAGFAARGWLDEGAPEGLLRLSPTGLAHSDALGPALFSPGVRAAMAAYE
                     RK"
ORIGIN
        1 tccgggacgt ccgcgtgaga ctcgaacgtc tcagcgaaac caccatagca ccgccgccgc
       61 ccccggcccg gtcctcaggc cctcggcggc ggcccgctcc tccggcctca gtggcagagg
      121 cgcgcctcgt gctccgcgtg accgctcggc tccagctgga aggtgcagtg ctccacgtcg
      181 aagtggtccc cgaggcagcc ctgcagctcg tggagcacct tctcgtgccc tatcgagtcc
      241 agcatctcct ggcgcaccac cacatgggcc gagagcaccg gcatccccga ggtgatcgtc
      301 caggcgtgca ggtcgtggac gcccaggacg ccggggagcg ccgtgatgtg cgcccgtacc
      361 tccgccatgt ccaccccctt gggtgccgcc tccagcagca cgttcagggt ctcccgcagc
      421 agcttcaccg tgcgggggac gatcatcagg ccgatcacca gggaggcgat cgggtcggcg
      481 gcctgccagc cggtcgccat gatgatgccc gccgagacga tcaccgccac cgagcccagg
      541 gtgtccgcca tcacctccag ataggcgccg cgcacgttca ggctctcctt ctgcccgcgc
      601 atcagcaggg agagggagac gaggttggcc accaggccga cgaccgcgaa catgatcgcc
      661 aggccgccct tcgtctcggc cggggtgatg aaccggtcga ccgcctcgaa gatcaggaag
      721 gcgcccacgc cgagcagcag caggcagttg gcgagcgccg ccaggatctc ggcgcgggcg
      781 aagccgaagg tgcggttcgg cccggcgggg cggttggcga agtggatggc gagcagcgcc
      841 atcccgaggc ccagggcgtc ggtggccatg tgggcggcgt ccgcgatcag ggcgagcgag
      901 tcggagagca ccccgccgac gatctccatg accatcacgc tcagcgtgat cgtcagggcg
      961 acgcggagcc tgccccggta ggcggcggcc gccgttccgg tcgggggcgg tccgccgtgc
     1021 gtgtgcccgt ggtcgtggcc agcccccatg cgaaacgcct ccaggtccct gcgacagcgc
     1081 cggggcgaaa ccgcccgacg cggcccagtg aactacgggt ggggggtatc gggcaacacg
     1141 gtactgaaca ccgttgtcat atgctctgac ctgcggaaac gttccgcagg tcagagcgat
     1201 gaggtgatca tctacgggtt ccggggcggg cctggggatg acgcagacac cacccctccc
     1261 acgccgactc caccatcgag cggacgtccc ggcgggccgt ccatcccagc tcccggacca
     1321 tcagcgcgtc cgacgccacc gccctcggcg cgtccccggc ccgccgcggc tcgaccaccg
     1381 gctccaccgg gtacccggtc acctcgcgga tcacgtcgat cagctcccgt accgagacgc
     1441 cctcgccccg gccgacgttc agcgtcaggt cgccgccctc gcgcccggcc agcttccgcg
     1501 ccacggcgag atgggcctcg gccaggtcgg ccacgtggat gtagtcgcgg acgcagctgc
     1561 cgtccggcgt cgggtagtcg gcgccgaaga tccggggggc ctcgccgcgc gtcagccggt
     1621 cgaagaccat cgggacgatg ttgaagaccc cggtgtccgc cagctcggga ccggccgccc
     1681 ccgccacgtt gaagtaccgc agacaggcgg tggagattcc gtgcgccttc ccggccgccc
     1741 gcaccagcca ctcacccgcg agtttggtct ccccgtacgg gttgatcggc aggcacggcg
     1801 tctcctccgt gatcagatcc acatccggta cgccgtacac ggccgccgac gacgagaaga
     1861 ggaagcgccg cacccccgcc gcgaccacgg cctccagcag cacgcccagc ccggcgacgt
     1921 tctcccggta gtacagcagc ggccgctcca ccgactcgcc gacctgcttc ttcgccgcga
     1981 ggtgcaccac accgctcacc gcgtgctcgg cgagcacccg gtccagcagc gcccggtccg
     2041 cgatccggcc ctccaccagc gtgacggtgt ccggcagccg ctcgacgacc cccgaggagc
     2101 ggtcgtcgag caccacgacc cgctctcccg ccgcggccat ggcccgcgcc acgtgtgccc
     2161 cgatgtatcc cgccccgcct gtgatcagcc atgtcatgtc ggccagccta agggcccctg
     2221 cggccgtgac ccgcgcgcgg tttgtggggc ggggcatcga tcgtcgatga tgatcgcgga
     2281 cggaaccggg ccgatcatga ccacccgaac ggagcacaaa cgggtggtga actcgccctt
     2341 ccgtacatcc gataacctca gccgacatgc cgccggcccg cctcgtggcc gtgctgccgt
     2401 gtgtcgtcca ccccgtcagt gccaaggagt gagttcgtct gtcgaccgcc atcctcaccg
     2461 gtacgccggt acccggctcg tcgctcgcgg acgacctgcg gtccctgggc ttcgacgtgc
     2521 tcaccgccgc cgacgccggt gacgccgcag cactcctcgc cgccgtcccg gccggccgcc
     2581 gggtcgccct cgtcgacccg cgcttcgtgg gccacgtcca cgcgctgcgg ctcggactga
     2641 ccgacccgcg cttccccgcc gccgccgtcg ccggcgcgct caccgcccgg gcggaggccc
     2701 gcccggccct ggtacgcgcc ctgcagcgca ccaccgcgac ggtcgtcgcc gggacctcca
     2761 ccgccgtacc ggaagcaggg gcggagaccg ccccgcagac cggcgaggag ccggcggccg
     2821 accggacgac cggtcggacg gcggccggcg cggcacccga ggaccccacc ctccccggcc
     2881 gcaccgccgc cgcgctggag gccgagggca cccccgtcca ccgccccgca ctcggctccc
     2941 tggtcgcggc cgtccccgcc gacgccgagc aggaggccgc cgccgtggcc gggatcacct
     3001 cggtcgacga cgaggcggta cggctgcgca gcgcggtcaa ggcccacgac gggttcttca
     3061 ccaccttctg catcagcccc tactcccgct acatcgcccg ctggtgcgcc cgccggggcc
     3121 tcacccccaa ccaggtcacc accgcgtccc tggtcaccgc gctcgtcgcg gcgggcgcgg
     3181 cggccaccgg aacccgcggc ggctacatcg cggccgggct cctgctcctg gtctccttcg
     3241 tgctcgactg caccgacggg cagctcgccc gctactcgct gcagtactcc acgatgggcg
     3301 cctggctgga cgccaccttc gaccgggcca aggagtacgc gttctacgcg ggcctcgcca
     3361 tcggcgccgt acgcgggggt gacgacgtct ggaccctggc gctcggcgcg atggtcctcc
     3421 aggcctgccg ccatgtcgtg gacttctcgt tcaacgaggc caaccacgac gcggtcgcca
     3481 acaccagccc caccgccgcc ctctccagca agctcgacag cgtcggctgg acggtctggg
     3541 cgcgccggat gatcgtgctg ccgatcggtg agcgctgggc catgatcgcc gtgctcacgg
     3601 ctctgaccac cccgcgcatc gtcttctacg ccctgctcgt cggctgctcc ctcgccgcct
     3661 gctacaccac ggcgggccgc ctgctgcgct cgctgacccg caaggcccgg cgcaccgacc
     3721 gggccgcgca ggccctggcg gacctggccg actcgggacc gctcgcccag gccgtcgccg
     3781 ccgtctcccc cggcctccgg ggcgcgttca cggtccccgc cgcggccctg ctcggggcgc
     3841 tcgtgatggt cggctcggcg ctcttcctcc cgtacggcag ccggctcacc gtcgtcgccg
     3901 ccggggtgta cgtggtcctc tccgggctcg ccgtcgcccg cccgctcaag ggcaccctgg
     3961 actggctggt gccgccggtc ttccgggccg ccgagtacgt cacgatcctg gtgctggccg
     4021 cgcgcagtga cgtcccccac gccgttcccg cggccttcgg gctggtttcg gccgtcgcct
     4081 accatcacta cgacacggtg taccgcatcc gcggtggcac cggcgcgccg ccccggtggc
     4141 tggtgcggac gatcggtgga cacgagggcc gcaccgcgct ggtggccgtc ctcgccgccg
     4201 tactcaccca cgcctcaggt ttcaccaccg cgctcaccgc cctcgcggtg gccgtggctc
     4261 tggtggtgct cgtggagtcc atccgcttct gggtgtcctc ctcggccccc gccgtacacg
     4321 acgaaggaga actcgcatga tcggcctcgt actggcagcc ggtgcaggac gacgtctgcg
     4381 cccctacacg gacacgctcc ccaaggcgct cgtccctgtc gacggcgaca agacggtcct
     4441 cgacctcacc ctcgccaact tcgcggcggt cggactgacc gaggtcgcga tcgtcgtcgg
     4501 ctaccgcaag gaagccgtct acgcgcgcaa ggccgagctg gaggccacgt acggcctcac
     4561 catcacgctc atcgacaacg acaaggccga ggagtggaac aacgcctact ccctgtggtg
     4621 cgcccgtgac gtcatcaagc gcggggtgat cctcgccaac ggcgacaccg tccacccggt
     4681 ctccgtcgag aagaccctcc tggaggcccg cggcaagggc cagaagatca tcctcgccct
     4741 cgacaccgag aagaccctcg cggacgagga gatgaaggtc atagtcgagg agggcaaggg
     4801 cgtccagcgc atcaccaagc tgatggaccc ggcctccgcc accggcgagt acatcggcgt
     4861 caccctcatc gagggcgagg ccgccgagga gctggcggac gcgctgaaga ccaccttcga
     4921 gcgcgacccc gacctctact acgaggacgg ctaccaggag ctggccaacc gcggcttcac
     4981 cgtcgacgtg gcccccatcg gcaccgtgac ctgggtcgag atcgacaacc acgacgacct
     5041 gaagaagggc cgtgaaatcg cgtgccagta ctgacccggc tcattccgtc cccggtcgtc
     5101 gtcgacatcc ggcgcggcgc catggacgat ctggcgggtc tcctggccga tcagcggatc
     5161 tcctcctccg gccggctcgc cgtcgcgatc agtgacggct ccgggcgcgc cctcaaggag
     5221 cggctcgccc cggacctgcc gggcgccgac tggtaccccg tctccgacgg gacgatcgac
     5281 tccgcggtga agctcgcgga cggcatcaag ggcaaccgtt acgacgccgt ggtgggcctc
     5341 ggcggcggca agatcatcga cgtggcgaag tacgccgcgg cgcgggtcgg gctgcccatg
     5401 gtcgccgtcg cgacgaacct ctcgcacgac ggcctctgct cgccggtcgc cacgctggac
     5461 aacgacaacg ggcgcggctc ctacggggtg cccaccccga tcgccgtggt catcgacctc
     5521 gacgtgatcc gtgaggcgcc cgtccggttc gtccgctccg gcatcgggga cgcgatctcc
     5581 aacatctcct gcgtcgccga ctgggagctg gcgcacgagg tcaacggcga ggagatcgac
     5641 ggtctcgcgg ccgcgatggc ccgccaggcc ggcgaggccg tgctgcgcca cccgggcggg
     5701 gtcggtgacg actccttcct caaggtgctg gccgagggtc tcgtgctgac cggcatctcg
     5761 atgtcggtcg cgggggactc gcgtccggcg tccggcgcct gccacgagat caaccacgcc
     5821 ttcgacctgc tctaccccca gcgcgcggcc agccacggcg aacaggtcgg cctcggcgcc
     5881 tgcttcgcca tgcatctgcg cggtgcccac caggagtccc tcctgatggc atcgatactg
     5941 cgccgccacg gcctgccggt cctgcccgag gagatcgggt tcaccgtgga cgagttcgtc
     6001 cgggccgtcg actacgcgcc gcagacgcgc cccgggcgct tcacggtcct ggagcacctc
     6061 aacctgtcca ccgaccagat cagggacgcg tacgccgact atgccaagac catcagtagc
     6121 tgaactccgc ccggtcgtgc acccggccgg ggtgaaggac cggcgcagcg gcgagcactg
     6181 ggccgggcgg ctgtacatgc gcgaggtctc cctgcgggtg gaccgctacc tggtcaacac
     6241 ccgggtgacg ccgaaccagg tcacgtacgt catgaccctg gccgccgtcc tcgccgcccc
     6301 ggccctcctg gtgccgggca tcccgggcgc cctgctcggt gtgctgatgg tccagctcta
     6361 cctgctgttc gactgtgtgg acggcgagct ggcccgctgg aagaagcagt actcgctcag
     6421 cgggatctac ctggaccggg tcgcggccta cctctgcgac gcggcggtcc tcgtcggcct
     6481 cggcctgcgt gccgcggaca tctggggcga gggccggacc gactggctct gggccttcct
     6541 cggcaccctg gccgccctcg gcgcgatcct gatcaaggcc gagacggacc tggtcggggt
     6601 ggcccgccac cagggcgggc tgccgccggt caaggagtcg gcctccgagc cgcgctcctc
     6661 cggcatggcg ctggcccgcc gggcggccgg agcgctcaag ttccaccggc tgatcctcgg
     6721 gatcgaggcc tcgctgctga tcctgctggt ggcgatcgtc gacaccatcg gcggcgacct
     6781 cttctacacc cgcctggcca cggccgtcct ggccgggatc gcgctgctgc agaccctgct
     6841 gcacctcgtc tccgtcctgg cgtccagcag gctgaagtga ccccagccat gaaactgggc
     6901 gcggtgatca tcaccatggg caaccgcccg gacgaactcc gcgccctcct cgattcggtc
     6961 gccgcccagg acggggaccg gatcgaggtc gtggtggtcg gcaacggcgc cccggtcccc
     7021 gacctcccgc ccggggtacg gaccgtggag ctgcccgaga acctgggcat ccccggcggc
     7081 cggaacatcg gcatcgaggc gttcggcccc tccggcgccg acgtggacgc cctgctcttc
     7141 ctcgacgacg acgggctgct gcccgaccgg ggcaccgccg agctgtgccg gcgggcgttc
     7201 gaggcggacc cggggctcgg catcctcacc ttccggatca ccgaccccga cacgggcacc
     7261 acccagcgcc ggcacgtgcc ccggctccgg gcggccgacc cgctgcgctc ctcgcgggtc
     7321 acgaccttcc tcggcggcgc gaacgccgta cgcaccaagg tcctcgccga ggtcggcccg
     7381 ctgcccgagg agttcttcta cgcccacgag gagaccgacc tcgcctggcg ggcgctggac
     7441 gcgggctgga tgatcgacta ccgcgcggac ctggtgctgc accaccccac cacggccccc
     7501 tcccggcaca cggtctacca ccgcatggtg gcccggaacc gggtctggct ggcccgccgc
     7561 aacctgcccg ccccgctgat cccgctctac ctgggggtct ggctgctgct caccctggtc
     7621 aggcgcccgt cgccgcccgc gctgaaggcc tggttcggcg gtttccggga aggctggtcg
     7681 acgccctgcg gaccccgccg cccgatgaag tggcgtacgg tgtggcggct gacgaggctg
     7741 ggccgacctc cggtcatctg agactctgtc ctctgagacc atgaggcgta ttttctttcc
     7801 ggaacctgtc cgcctgagcc gcgcccgcga ctggctgcgc gtgaagacga gagtttcaac
     7861 ttgtgagtga cacgacccac gacggtgggg tagccctcgg gaccccgccg tccgccgacg
     7921 agggcctcgg cccggctcag ctggccgcca agtacggcct gaccgtgagc ggtgcccggc
     7981 ccgggctgtt cgaatacgtg cgacagctct ggggccggcg acatttcatc ctggccttct
     8041 ccagggcgaa gctgaccgct cagtacagcc aggccaaact gggccagctg tggcaggtgg
     8101 tcacccctct cctgaacgcc tgtgtctatt acctgatctt cggactgatc ctggggacca
     8161 gggaggggat tcccgatgac gtcttcgtgc cgttcctggt caccggcgtc ttcgtcttca
     8221 ccttcaccca gagctccgtg atggcgggag tccggtcgat ctccggtaac ctcggactgg
     8281 tccgggccct ccacttcccc cgggcctcgc tccccatctc gttctcgctc cagcagctcc
     8341 agcagctgct cttctcgatg atcgtgctgg tcacggtggc catcatcttc ggcagctacc
     8401 cctcgctctc gtggctcctg gtgattcccg ccctgatcct ccagttcgtc ttcaacaccg
     8461 gcctggccct catcatggcg cggctcggct ccaagacccc cgacctcgcg cagctgatgc
     8521 cgttcatcat gcgcacctgg atgtacgcct cgggcgtcat gttctccatc ccggtgatgc
     8581 tcaaggacaa gccgcagtgg atcgccgacg tgctccagta caacccggcg gccgtctaca
     8641 tggacctggt ccgcttcgcc atgatcgacg ggtacggctc cgagaacctg ccggaccacg
     8701 tctgggccgt cggcctcggc tgggccctgc tgctgggcgc cgtgggattc gtgtatttct
     8761 ggaaggcaga ggaacggtac ggccgtggct gaggacaaca cgcagggacg gactcccacg
     8821 gtcatcgccg atgacgtcca catcgtctac cgggtcaacg gcggtggcgg cggccggggc
     8881 agcgccacgg cggcgctgag ccggatgctg cgccgcggca agggcgagca gcgcggggtc
     8941 aggaaggtgc acgccgtgcg cggcgtctcc ttcaccgcct accggggcga ggccatcggc
     9001 ctcatcggca ccaacggctc cggcaagtcg acactgctgc gggccatcgc cggtctgctg
     9061 ccgacggagt ccggccgggt ctacaccgac ggccagccct cgctgctcgg ggtgaacgcg
     9121 gcgctgatga gcgacctgac cggtgagcgc aacgtggtgc tgggcggcct ggccatgggc
     9181 atgtcccagg ccgagatccg ctcccgctac caggagatcg tggacttctc cggcatcaac
     9241 gagaaggggg acttcatcac ccttccgatg cgcacgtact cctccggcat ggcggcgagg
     9301 ctgcgcttct ccatcgccgc cgccaagaac cacgacgtcc tcatgatcga cgaggcgctg
     9361 gccaccggtg accacaagtt ccgcgtccgc tccgaggcgc ggatccgtga actccgcaag
     9421 gaggcgggca cggtcttcct ggtcagccac aacaacaagt cgatcaggga cacctgcgac
     9481 cgcgcgctct ggctggagaa gggcgagctg ctgatggacg gtcccaccga ggaagtcctc
     9541 aaggcgtacg aacgcgagac gggcaagtag tttcccagcc actgtggcct ccgccggacc
     9601 gttccggtgg gggccacagc ggtgtgcggg gcggtgcacg gcccggcgga ggccccccgc
     9661 agtacgcatc cgggggtgat ctcctcccgg cggatgacgt caacccgccg acgtacggag
     9721 aaggttgacg tgcggcaccc tgccgccgcc gcgggccgct ccaccccgcc gcacccctgt
     9781 gagctgcaca acgtaggctg tagcggtgct gattcatggc aagtggggcg atacgccccc
     9841 ggcgctccgc ccgctgtgcc gcagtgcact cggaagaacg agcggcgtgt ccgaaaaggg
     9901 atgttttggg tcagcagtgt agaacgggag atgtgacggc aatgacggaa gatctccagc
     9961 tccgacgtgc tcccgccgtc cccgcgccgg gcggtccgca gtgacctcca ccccgcaggc
    10021 gcgcaccggc gacgccaccc tcggcaaggc cgcggacgag aacttccccg tggccccctt
    10081 cttcctgccc cgcgcctggc gcgacgacct gatggcggtc tacggcttcg cccggctcgt
    10141 cgacgacatc ggtgacggcg acctcgcccc cggcggcgcc gacgcccgcc acctgggcct
    10201 ggagcctgag cagagcgacg accggctcgc catgctcgac gccctcgaag ccgacctgca
    10261 ccgggtcttc gccgccaccg gccaggagcc gcaccacccc ctgatgagcg ccctgcgccc
    10321 caccgtgcgg cgccgcgcgc tcacccccga acccttcctc gggctgatcg aggccaaccg
    10381 gcaggaccag aaggtccgcc gctacgccac ctacgaggag ctggccgcct actgcgagct
    10441 ctccgccaac ccggtcggcc gcctggtcct cgccctcacc ggcaccacca gcccggaacg
    10501 ggtccgccgc tccgacgcgg tctgcacggc gctccagatc gtcgagcacc tgcaggacgt
    10561 ggccgaggac ctcgcccgcg accggatcta tctgcccgcc gaggacatgg accgcttccg
    10621 tgtctccgag gccgacctgg cccggcccac cgccggcgcc tcggtccgcg ccctgatcgc
    10681 gtacgaatcc gaacgcgcga gcgagctgct ggacgagggc atccccctcg tgggcagcgt
    10741 cgacggcagg ctcaggatcc tgctcgccgg tttcgtcggc ggcggacgct ccgccctcac
    10801 cgcgatctcg gccgccgggt tcgacgtact gccggggccg cccaagccca ccaagccgag
    10861 catgctgcgc gaagtcgcag tcgtcctgcg aagagcgcgt agagagaggt gagcttgacc
    10921 gtggagggac agacgacgca catgtcgccg ccggtccagg ccgcatacag ttactgcgag
    10981 gccgtcaccg ggcagcaggc ccgcaacttc gcctacggca tcaggctgct gccgtacgag
    11041 aagcggcagg ccatgtcggc gctgtacgcc ttctcccgtc gcgtcgacga catcggtgac
    11101 ggcgagctgg acccggcgac caagcggacc cggctggaga gcacccgcga actgctcgac
    11161 cggatccggc acggcaaggt cgaggaggac gacaccgacc cggtggccgt cgccctcgcc
    11221 gacgccgccc gccgcttccc gctgccgctg gaaggcctcg acgagctgat cgacggcgtc
    11281 ctgatggacg tccgcagcgc cacgtacgag acctgggacg acctgaagac ctactgccgc
    11341 tgcgtcgccg gtgccatcgg ccgcctcagc ctcggggtct tcggcacgga accgggcgca
    11401 cccggcgccg agcgggcctc cgagtacgcc gacaccctcg gcctcgccct ccagctcacc
    11461 aacatcctgc gcgacgtccg cgaggacgcc ggcaacgggc gcacctacct ccccgccgac
    11521 gacctggcca aattcggctg ttccgccggc ttccacggca ccaccccgcc gcccggctcc
    11581 gacttcgcgg gcctgatcca cttcgaggtc cgccgggccc ggaccctctt cgccgaggga
    11641 taccgcctgc tgcccatgct ggaccgccgc agcggcgcct gtgtcgccgc catggccggg
    11701 atctaccgcc gcctgctgga ccggatcgag cgcgacccgg aggccgtgct gcgcggccgg
    11761 gtctcgctgc ccggccacga gaaggcgtac gtcgcggtgc gcggcctctc cggcctggac
    11821 gcccgccatg tctcccggct gacctcccgg gggcgagcct gatgcgttcc ggcgggccgg
    11881 gcgcccggtc aaccctcggg tggccgcacg cgtccacgac tgcgacgatc actaccggga
    11941 cgacccggcg accggtgacg gcccggcgag aggggcaggc atgagcgacg agacaccgcg
    12001 ccccgtcgcg gtcgtcgtcg gcggcggact ggccggcatc acggcggccc tccgcctcgc
    12061 cgacgccgga ctcgacgtca ccctgctgga agggcggccc cgcctcggcg gcctcgcctt
    12121 ctccttccag cgcggcgacc tcaccgtcga caacggccag cacgtctacc tgcgctgctg
    12181 caccggctac cgctggttcc tcgaccgcat cgacggcgcc cacctcgccc ccctccagga
    12241 ccgcctggac gtccccgtcc tggacgtcgg ccgcgccgcc ggaccccgcc tcggccggat
    12301 ccgccgcacc gggctgcccg taccgctgca cctcgccgga gggctcgccg cctatccgca
    12361 cctctccctc gcggagaagg cgaacgtcgg ccgcgccgcc ctcgcgctcg gccgcctcga
    12421 ccccgccgac ccggccctcg acgagatcga cttcgccacc tggctgaagc ggcacggcca
    12481 gtccgagcgc accgtcgagg ccctctggga cctcgtcggc gtcgccactc tgaacgccac
    12541 cgcgccgaac gcctccatgg cgctcgccgc gaaggtcttc aagaccggcc tgctctccga
    12601 acccggcgcc gccgacatcg gctgggccac cgtgccgctc ggcgaactgc acgacaccct
    12661 cgcccgcaag gccctggaca ccgcgggcgt ccgcaccgag ctgcgcgcca aggtggggtc
    12721 cctcacccgt accgaggacg gccgctggag cgtcgagacg gcgggggagc ggctcaccgc
    12781 cgagaccgtc gtcctcgccg tgccccagca cgagacccac gacctgctgc ccgccggcgc
    12841 cctggacgag ccggacctgc tgctcgacat cgacaacgcg cccatcctca acgtgcacgt
    12901 gatctacgac cgcacggtgc tgcgccgccc gttcttcgcc gcgatcggct ccccggtcca
    12961 gtgggtcttc gaccgtacgc actcctcggg gctgaagggc cccggccagt atctggcggt
    13021 ctcccagtcc gccgcccagg acgagatcga cctgcccgtc gccgagctgc gggagcgcta
    13081 cctccccgag ctggagcggc tgctgcccgc cgcacgcggc gccggcatcc gggacttctt
    13141 cgtcacccgc gagcgcaccg ccaccttcgc gcccgccccg ggcaccggcc ggctgcgccc
    13201 cgggccccgt acgcgggcgg ccgggctgca cctgtcggga gcctggaccg acaccggctg
    13261 gcccgcgacg atggagggtg ccgtgcgcag cggctcccag gccgccgacg cggccctcca
    13321 cgacctcggc cgcccccaag gacatccgct gcaggaggcg gcatgagcag taccaccgga
    13381 acaagaggag agtcagtgac cccggcgaat ccggcttccg acaccgtgga ccagaccacg
    13441 gacgtcaccg cgcttctgga gcgcggacga gccctgtcag cgccggtgct gcgggccgcc
    13501 gtggaccggc tggcgccgcc catggacacc gtcgcggcct accacttcgg ctggatcgac
    13561 gccgagggac ggcccgcgga cggtgacggc ggcaaggccg tgcgccccgc gctcgccctg
    13621 ctgtcggccg aggcggccgg cgcccccgcc gaggcgggcg tccccggcgc cgtcgccgtc
    13681 gaactcgtgc acaacttctc gctgctgcac gacgacctga tggacggcga cgaacagcgc
    13741 cgccaccgcg acaccgtatg gaaggtgcac ggacccgccc aggcgatcct ggtcggcgac
    13801 gcgctcttcg ccctcgccta cgacctgctg ctggagctgg gcacggtcga ggcgggccgc
    13861 gcggcccgcc ggctgacctc ggccacccgc aagctcatcg acgggcaggc ccaggacatc
    13921 tcctacgagc accgcgagcg ggtcaccgtc gaggagtgcc tggagatgga gggcaacaag
    13981 accggcgccc tgctggcctg cgcggtctcc atcggcgcgg tgctcggcgg cgccgacgac
    14041 cgtaccgccg acaccctgga ggcgtacggc taccacctgg gcctcgcctt ccaggccgtc
    14101 gacgacctgc tcggcatctg gggcgacccg gaggccaccg gcaagcagac ctggagcgac
    14161 ctgcgccagc gcaagaagtc cctcccggtc gtcgccgcgc tcgccgcggg cggtccggcc
    14221 tccgagcggc tcggggagct gctcgccgcc gacgccaaga gcaacgactt cgacagcttc
    14281 tccgaggagg agttcgccgc ccgcgcggcg ctcatcgagg aggcgggcgg ccgcgagtgg
    14341 accgcccagg aagcccgtcg gcagcacgcg gtcgccatcg aggcgctgca cggtgtcgac
    14401 atgccacatc aggtacgggc gcagctcacc gcgctcgcgg acttcgtggt ggtgcggaag
    14461 agatgaccag cacccgtata tgacgcgcag tcgccggccg acgccccgcc cggggcgtcg
    14521 gccgacggag accccagcac agcagagaaa ccactgcacg taaggggaag ctcatgacag
    14581 cgacgactga cggacccgcc ggggccgcgg aactctccgc gaccacggca ggacatccgg
    14641 accgcacgac cctcgtcccg gacgaggtgc tcgccgccgc gcggcgggcc gccgaacgct
    14701 ccgtggagca ccttctcggc agacaggacg agcagggctg gtggaagggg gacctcgcca
    14761 ccaacgtcac gatggacgcc gaggacctgc tcctgcgcca gttcctgggc atccaggacc
    14821 cggagaccac ccgcgccgcc gccctcttca tccggggcga gcaactgggt gacggcacct
    14881 ggaacacctt ctacggcgga ccgagcgacc tctccgcgac catcgaggcc tatgtggccc
    14941 tgcggctggc cggggacgcc ccggacgcac cgcacatggc ccgcgccgcc tcctggatca
    15001 gggagcaggg cggcatcgcg gccgcccggg tcttcacccg catctggctg gcgctcttcg
    15061 gctggtggaa gtgggacgac ctccccgaac tcccgcccga gctgatgttc ctgccctcct
    15121 gggtcccgct caacatctac gacttcggct gctgggcccg gcagaccatc gtccctctga
    15181 ccgtcgtctc cgcgaagcgc cccgtccggc ccgcgccctt cgccctggac gagctgcaca
    15241 ccgacccggc ccgccccaac ccgtccagga agcttgcccc ggcggccagt tgggacggac
    15301 tcttccagcg tctggacaag gggctgcacc tgtaccacaa ggtcgccccg cgcccgctgc
    15361 gccgcatcgc gatgaacgtg gcggcccgct ggatcgtcga acgccaggag aacgacggct
    15421 gctggggcgg catccagccc ccggccgtct actccctcat cgccctgcat ctcctcggct
    15481 acgacctgga ccatccggtg atgaaggcgg gcctcgcctc gctggaccgg ttcgccgtcc
    15541 accgcgagga cggggcccgg atggtcgagg cctgccagtc gcccgtctgg gacacctgtc
    15601 tggccaccat cgccctggtc gacggcggac tcagacccga ccacccggcg ctggtgaagg
    15661 ccgccgactg gatgctcgcc gaggagatca cccggcccgg cgactggtcc gtacgcaaac
    15721 ccggactcgc ccccggaggc tgggcgttcg agttccacaa cgacaactac ccggacatcg
    15781 acgacaccgc cgaagtcgtc ctggcactgc gccgggtccg ccaccccgac cccgcccggg
    15841 tggaggccgc catcgagcgc ggggtccgct ggaacctcgg gatgcagtcc cgcaacgggg
    15901 cctggggcgc cttcgacgcc gacaacacca gctccttccc caaccggctg cccttctgcg
    15961 acttcggcga ggtcatcgac ccgccgtcgg ccgatgtcac cggccatgtg gtggagatgc
    16021 tcgccgtcga ggggcgcgcc cggcaccccc gtacgcgacg gggcatcgag tggctgctcg
    16081 ccgaacagga ggcgtgcggg gcctggttcg ggcgctgggg cgtcaactac gtctacggga
    16141 ccgggtcggt ggtccccgcg ctgatcgccg ccggactgcc cgccgcccac ccctcggtcc
    16201 gccgggcggt ggagtggctg gagtccgtgc agaacgacga cggcggctgg ggcgaggacc
    16261 tgcgctcgta ccgggaggag aagtggatcg ggcacggtga gtccaccgcc tcccagaccg
    16321 cctgggccct gctcgccctg ctggcggcgg gccgcggcga cagcgtcgcc gtcacccgcg
    16381 gggtcacctg gctgaccgac gcccagcagg ccgacggctc ctgggacgag ccgtacttca
    16441 ccggtaccgg cttcccctgg gacttctcca tcaactacca cctctaccgc caggtcttcc
    16501 ccctcacggc actcgggcgc tacgtgtacg gcgacccctt cgccgaccgt acgggcgccg
    16561 cccaggacgc ctgatgggcg gcgcaccggg gtccgggagc ccccaggcgc cgccgccgct
    16621 gctggtcgcc tgcgccctgg gcatcgagca ggtggccctg cgcagcggca gacgtcccgc
    16681 gggcccggtc cgggtcctgc ggaccggaat gggcccccgg gcggcggagg cggccgtggc
    16741 ggccgccctc gcccccggtg gcgcccccga ggccgccgtc atcgcctccg gcttctgcgc
    16801 gggcctggcc cccgggatgc accccgggga cctggtcgtc gccgaggagg cccgggacgc
    16861 ggacggcgcc accccctgca ccggcaccgg actgctggtc gccgccctgg ccagggccgt
    16921 ccccggcgcc accgtccaca ccgggcccct gaccggctcc gaccacgtcg tccgcggccc
    16981 cgagcgggcc gcgctgcggg cgaccggggc catcgccgtg gacatggagt ccgccgcgac
    17041 actgcgcacc gccctgtgcc acgggccgcg cccggttgcg gccgtccggg tggtcgtgga
    17101 cgctccagag catgagctgg tccgtatcgg cacggtccgc ggtggaatat cggccttccg
    17161 tgttctccgt gccgtccttc ccgctttcta cgaatggcac cgatctttac tgctccccag
    17221 gaggtgagcc agatggccat gccgctccgt cagtccatca aggtcgcgac gtatctcttc
    17281 gagcagaagc tccgcaagcg tgagaagttc ccgctgatcg tcgagctcga gccgttgttc
    17341 gcctgcaacc tcgcgtgcga gggctgcggg aagatccagc acccggccgg tgtcctgaag
    17401 cagcgcatgc cggtcgccca ggccgtgggc gcggtgctcg aatccggtgc ccccatggtc
    17461 tccatcgccg gcggcgagcc gctgatgcac ccgcagatcg acgagatcgt gcgccagctc
    17521 gtcgcgcgga agaagtacgt cttcctctgc accaacgcga tgctcatgag gaagaagctc
    17581 gacaagttca ccccttcgcc ctacttcgcc ttcgccgtgc acatcgacgg actgcgggag
    17641 cggcacgacg agtcggtcgc caaggagggc gtcttcgacg aggcggtgga ggcgatgaag
    17701 gaggccaagc ggcgcggctt ccgggtcacc accaactcca ccttcttcaa caccgacacc
    17761 ccgcagacca tcatcgaggt cctcaactac ctcaacgacg acctgaaggt cgacgagatg
    17821 atgatctcgc ccgcctacgc ctacgagaag gcacccgacc aggagcactt cctcggcgtc
    17881 gaccagaccc gcgaactctt caagaaggcc ttcgcgggcg gcaaccgggc ccgctggcgg
    17941 ctcaaccact cgccgctctt cctggacttc ctggagggca aggcggactt cccgtgcacc
    18001 gcctgggcca tccccaacta ctcgctcttc ggctggcagc gcccctgcta cctgatgagc
    18061 gacggctacg taccgacgta ccgtcagctc atcgaggaga ccgactggga caagtacggc
    18121 cggggcaagg acccgcgctg cgccaactgc atggcccact gcggctacga gcccaccgcc
    18181 gtcctcgcga ccatgggatc gctcaaggag tcgctgcgcg cggcccggga gagcgtcggc
    18241 ggcaaccggt gacggacggc gggccgcagg gcttcgacct cgggcggctg ctggcggagc
    18301 gcgggggcga gcggtacgag ctgcacgcgc gccacctcaa ccaccagctg ccgcgcatgc
    18361 tgcacaccat cggcttcgac aaggtctacg agcgggccga gggcgcgtac ttctgggacg
    18421 ccgacggcca ggactacctg gacatgctgg ccgggttcgg cgtcatgggg ctcggccggc
    18481 accacccggt cgtccgccgg gccctgcacg acgtgctcga cgcccagctc gccgacctca
    18541 cccgcttcga ctgccagccg ctgcccggac tgctggcgga gaagctgctc ggccacagcc
    18601 cgcacctgga ccgggtcttc ttcgggaaca gcggtacgga ggcggtcgag acggcgctga
    18661 agttcgcccg gtacgccacc gggaagcccc gggtcctcta ctgcgaccac gccttccacg
    18721 ggctgaccac cggctccctc tcggtcaacg gcgagcgcgg cttccgggac ggcttcgccc
    18781 cgctgctgcc cgacaccccg atcgccctgg gcgacctgga cgggctgcgc cgggagctga
    18841 agcgcggcga cgtggcggcc ctggtcgtcg agccggtcca gggcaagggg gtgcacgccg
    18901 cgcctcccgg gttcctgcgc gaggcacagg agctgctgca ccggcacaag gcgctcctga
    18961 tcgccgacga ggtgcagacc ggtctcgggc ggaccggtga cttctacgcc taccagcacg
    19021 aggaaggggt cgagcccgat ctcgtctgcg tggccaaggc gctctccggc ggctatgtgc
    19081 cggtcggcgc cacgctcggc aaggagtgga tcttccgcaa ggtctactcc tcgatggacc
    19141 gggtcctcgt ccactccgcg agcttcggct ccaacgccca ggccatggcg gcggggctcg
    19201 cggtgctctc cgtcatggag gacgaggaga ccgtcgcggg cgcccggcgc accggggacc
    19261 tgctgcgcgg gcggctggcg gcgctggtgg accgctacga gctgctgcac gaggtgcggg
    19321 ggcgcgggct gatgatcggc atcgagttcg gccgcccgtc ctcgctgaag ctccgcagcc
    19381 gctggaccat gctccaggcg gcccgcaagg gtctcttcgc ccagatggtc gtggtgccgc
    19441 tgctccagaa gcaccgcatc ctcacccagg tctccggcga ccatctggaa gtgatcaagc
    19501 tgatcccgcc gctgatcatc ggggaggcgg aggtggaccg cttcgtggcg gcgttcaccg
    19561 aggtcatgga tgacgcccac agcgggggcg ggctgatgtg ggacttcggc cggaccctgg
    19621 tcaagcaggc cgtggccaac cgctgaggcc gaaggatttg cctcccgggc aatttatttg
    19681 cccgggagga aagttcctgg cccaatggaa ccatgaaccc tcaggacgag ggggcggccg
    19741 acgagcttcc cggcgtcgcc ccccgactgc gcgaactgcg ccgtgggcgc ggcatcaccc
    19801 tggagaccgc cgcccagcgg gccggactct ccccggccca cctctcccgg ctggagaccg
    19861 gccgccgcca gccctcgctg ccgatgctgc tgggcctggc ccgtatctac ggtacgacgg
    19921 tctccgagct gctcggcgag aagccccccg agcgcgacgc gatcatccgg ggcggcgcct
    19981 tcgagggcgc cgaggccgac ggctggatgt accgccgggc cggcagcccc ggccgcgcca
    20041 tgcaggcgct gcgggtccgt gtcccgtacg gcgcccaggg cgatctggtc cgcgtgcacc
    20101 ccggtgagga gtggctgtac gtcgtcggcg gacggcttcg ggtcgcgctg ggggagaccg
    20161 tgcacgatct ggacccgggc gacagcgccc acttcgactc gctcaccccg caccggatcg
    20221 cggccctgga ccgcggcggg gcggagctgc tcttcgtcca ctccctgctc cagagccccg
    20281 cggccgagct gtgcctcggc aacgccctcc acgcgcgctg accccgcgta ccaccggggc
    20341 ccgcacacct ccggaccttc gtgctccgga ccccccgcac ctccggaccc ttcgcaccca
    20401 ccggccgtga ggccggcaga gaggaccgtc atgtccgatt ccgaacacta cgacccgctg
    20461 agtccccggc ggccgagggc cacgaaggac gcgcaggagc gccggatgcc gcgcggtctg
    20521 gtgatccgcc tcgtcgccta cctggtggtc ggccatgtga tcgcggcctt cctctacctg
    20581 ctcttcatgg tggcgggcgc ggagtagccg ctcagccctg gtcgagcagg cgctcgcgca
    20641 gccgctcccg ggtggcggcg gagacgccca gcccctccga gagatagcgg tccgtcgagc
    20701 cccaggtctc gtcgatggcc gtgaacgccg ccgcgaggta ggaggactgg gccccgaaga
    20761 gcgggttgag cagctccatc acctcggggg acatccccgt cgcggacatg tccgtgcgct
    20821 tcaccttgta ccggcggtgc gggtcgttgg acttgaggta gtccgcctcg atcgcctcgc
    20881 gctcgacgcc gaccgcgagc agcgagaccg cgatcgacag ccccgcccgg tccttgcccg
    20941 ccgcgcagtg catcagggcc ggaacgctgt cctccgccag ggcgtggagg acgcggctgt
    21001 gctcggcggt gcggtccacg atggtcgcgc ggtacatgtg gagcatccgc tcggtgccct
    21061 tgccgccggc caggatcgag cgcagctgct cgatgttccc gtcgcgcacc agccgccaga
    21121 actcggctcc gtcggccgga tccgagagag gaatgctgac attacggaca ccggccaact
    21181 cgatgtcgta cccgtcgagc tggtggtcgg cggagttgcg gaagtcgaag acggtgtgca
    21241 gcccgagccc ggagaggaag gccgcgtcct cggcggtggc gtgtgccagg tggccgctgc
    21301 ggtagagccg gccgaaggcg gtgcgccgcc cgtccgtggt ggggagcccg cccacgtcgc
    21361 ggaagttgcg gactccgttc agtgcggtct cggtcggcgg gacctgcggc acctgctgcg
    21421 tcacggtggc tcctgaagtc tctggcgtcg gcgcggctct ccggcgaggg cgctcctgtg
    21481 acgatacgac atcgattcgg ccgaaaatca tgggacggat gacggggcgt cagaagtggc
    21541 gccgatggca tgtccgtatt ggtgcatttc gcagaacatg ccccgctagt gggggagatg
    21601 ggattccgtg ggtgagcggg atcatatccg tgacggaccg tggcgacgga gcccggtcgt
    21661 tttcccggga tccgtacgga aagccaagat ccgtaatcca cggagtgtga cgggaaatcc
    21721 ggggcggaat cgaatcgatg attccgggag gcaaccggcg gcttgttccc gtcgtcctga
    21781 ctcgtttacg gtcaccgtca atccggacgg accgcctaat cctgccgccg cccggaattc
    21841 gcacccaccc actcacgtgt ggcaggagcg ggggaaccag gtaagccgcc ggcccggagc
    21901 gatccggacc ggctaggggt gaagccgcca accggcggcc gggcatctcc agcccgaacc
    21961 cgacagctca cctcgcaggc gccggagagg aacttcccca tgcccgcaca gggtaagcac
    22021 cgccgtccca agtccggccc gatcacccgc ggcgtcctcg ccgcgggcac cggcggcgcc
    22081 gtactcgccc tcccgctgat cggcgccacc ggcgcccacg ccgcggagaa ggccgccccg
    22141 gccgtcaagc ccgccgccac ggccgccgtc gtgccggccg ccgccccgca ggccgcgccc
    22201 gccaaggcga agaccgcccc gaagacgtac tccgtcgtct ccggcgacta cctcgcgaag
    22261 atcgccgccg agcaccagct caagggcggc tggcagaagc tgtaccagga caaccgctcc
    22321 accgtcggcg agaaccccgg tctgatcttc ccgggcatga agctcaccct cggcgccaag
    22381 gccgccggct ccgcagcgcc ctccgaggcc aagaaggccg ccccggcgcc caagtccgcc
    22441 ccgaagaccg agaagaaggc cgcccccaag gccgcgccga agaaggccga gcaggcaccc
    22501 aagggcgaca ccatctcggc cgacgagtcg gacgccgcgc agaagcggag cggtgccacc
    22561 acccagaccg gcgcctcgca gtccaccggc tccggctgga ccgccccgct ggacagcgcc
    22621 caggtcacca cccagtaccg cgcctccggc tccagctggt ccagcggcta ccacaccggc
    22681 gccgacttcc gcgccgcctc cggcaccccc gtccgcgcca tcggcccggg caccgtggtc
    22741 tcggccggct ggagcggttc gtacggcaac gaggtcgtca tccgccacgc ggacggcatg
    22801 tactcccagt acgcccacca gtcctcgctg aacgtctcca ccggccagac cgtcaccggc
    22861 ggccagcaga tcggcctctc cggttccacc ggcaactcca ccggtccgca cctccacttc
    22921 gaggtccgca ccggcccgag ctacggctcg gacgtcgacc cggtcgccta cctgcgccag
    22981 cacggcgtct ccctctgacc cgagggcggc ccgcaccggg cgtgaagtga ccgagggcgg
    23041 tgtgctgtgg cacaccgccc tctacttatt ccggctttac ccaaatctga ccgggtggcc
    23101 tatgtcacca cccgtcaacc ccgtattacg gtcgcgtagg tcacattgaa cggtgcagga
    23161 tatgtgcttg tggcagacga ttcgagaacc cagcagcaga acaccatcgg gtcgtacgcg
    23221 gcgatcgggg acagtttcac cgaaggcgtc ggagaccccg gccccgacgg cacctttgtc
    23281 ggctgggcgg accggttcgc ggttctcctc gccgaccggc tcccggcccc cgacgcggcg
    23341 acgaacccgg acgagacccg gcacgggaat ttccgctacg ccaatctcgc cgtacgcgga
    23401 cgcctcctcg accagatcgt cgaggagcag atcccccgcg ccaaggagct ggcccccgac
    23461 ctggtcagct tctgcgcggg cggcaacgac atcatccggc ccggaaccga ccccgacgac
    23521 ctggccgagc ggtacgagaa ggccgtcgcg gagctgaccg aggcggtcgg ctccgtcatg
    23581 atcaccaccg gcttcgacac ccggggcgtc ccggtgctgc gccatatgcg gggcaagatc
    23641 gccacgtaca acgtccacct ccgggccatc gcggaccgct accgctgccc ggtgctcgac
    23701 ctgtggtcgc tgcgctcggt gcaggaccgg cgcgcctggg acgccgaccg gctccacctc
    23761 tcgcccgagg gccacacccg ggtcgcgctg cgcgccgccc aagtcctcgg ccacgacgtc
    23821 ccggccgacc cggaccagcc ctggccgccg caggcccagc gccgcccctt cgacgagagg
    23881 cgcgacaaca tccagtgggc gcgggagtac ctcgtgccgt ggatcgggcg gcggctgcgc
    23941 ggcgagtcgt ccggcgacca cgtcgaggcc aagcgcccgg acctgctgcc gctgtaacgg
    24001 caggttccca ggggctcagg ttctcaggga ttcaggggcc cggggttcag cagggggagc
    24061 gtacgccggg tcgggcccgg gaccaggggt ccgtccggcg ccgggcccgc gcccggcccg
    24121 gccggtatcc gctccagcac accgcccgcg aagacgtcgt acagcggcag cgtctccagg
    24181 tgcacatagc cgatgtggca gtcgcagacg gcgagcggac aggctcgcgg accgagcgcc
    24241 cggcggtagc tgccgtcgta cagattgccc agctcggcct tgacgaagtg acagcgccgc
    24301 acggtcccct cgccgtccac cgagatcacg gactcgcccg tccggcaggg cagcccggcc
    24361 gagcggtgcg gatgcctgct gtacgggaag agcgggtcca gctccgtcca ccgcgccgcc
    24421 tcctcgtccg tgtacgtccg cccctcggcg gcgttcaccc agaggtagac ctccgggggc
    24481 agcgccgccc gcagtcgccg ggcctcttcc agatgagcct cgaaccccac cacgcccaca
    24541 ctgaaccgga tgccccgggc cgacagctca cggcacttgc cgaggaaccg ctcgtacggc
    24601 gtctgccccg ggtggtacgt gcaccagagc gcgatccgct ccggatccgc gtccgcgagc
    24661 caggccgtac ggccgctcag attggtctgg atggcgaccc ggccgaggtg cgggagatgc
    24721 gacagctcgg tcagcgcccg ccggtaccag gaccggacca gcccctcgcc ccacggggtg
    24781 aacagtaccg agagccggtc gccggtctgc gccgccgccc acgccgtgaa ccgctccagc
    24841 gcctcccggt cggaggtcaa ctgcgcccgg ctgtcccgcc gtttggcgaa cgggcagtac
    24901 ggacagtcgt agtcgcacga ggccagcggg ccccggtaga ggatggtcag gtccacggcc
    24961 cgctcacttc cgctcgtacg cggccatcgc cgcccgcacc ccgggcgaga acagcgcggg
    25021 ccccagcgcg tcggagtggg ccaggcccgt cggggagagc cgcagcagcc cttccggcgc
    25081 cccctcgtcc agccagcccc gggccgcgaa ccccgccagc tcggcgggga agtccgccca
    25141 cgggtccgta ccgaagcggg cgcggtagtc ggccacgggg agaccggccg cctggaggac
    25201 ggactggagg aggtggcgcc tgcgggcctc ttcctcgtcg acgtaccgtc cgacctcggc
    25261 ccgggagaag tcctgggtgg cggtgaagga gtcgatgatg gagcggatct cccgcatgtc
    25321 gaccgcgtag tcgaaggagt agtgcagcgc ggaggtgtag gaacgggctc cgcagcccag
    25381 gccgatcatg ccgtcggtct ggcaggcgta gtcctcggga ccctcctggg gggcgtcggc
    25441 ccggcggaac atccgcatcg acacctgctc gtagccgtgc gccagcagat ggtcgcggcc
    25501 caccgcgtag agccgcagcc gctgctcgtc ccaggccgcc tgctccaggg cctccgcctc
    25561 cgggccgctc acacccgccc ccagccggtg caggccggtc agcgggcgga cgtacagcgg
    25621 gtagaggtac atctcctccg gccgccaggc cagcgcggcg tccagcgagg tgagccaggt
    25681 gcgctcggtc tggccgtcga tgccgtagat caggtcgatg ttcagcaggg gtatccgggc
    25741 gtcccggatc cggccgaggg cggcctccac ctcggcccgt cgctgcgggc ggacggccgc
    25801 cttggcctcg gcgtccacga agctctgcac cccgatactg atccgggtcg tgccccggtc
    25861 ggccagcacc gccagccggt cggcggtcgc ggtggacggc gaggtctcca cggagagcgg
    25921 caccgcgcgc aggtcggcgc ccatccgctt ctccgcgatg tcgcagagcc gctccagctc
    25981 gcccgccgtc aggaaggtcg gcgtcccgcc accgaaggcc gccgccgcga accgcaccgg
    26041 ctcgtcgtcg ccgagcccgt cccgtacggc cacggcctgc cggtccaggg cgtcgaggta
    26101 gcgggtcgtc agctcctcgg gcgcgccgat ccgggtgaag aggttgcaga agccgcagcg
    26161 gacctcgcag aacggtatgt gcaggtagag ggagagggcg tccttccgct cggtcgccca
    26221 cagctcccgc agcgcgggcc gttccggcag cgggcggtag gcggtcttgt gcggataggc
    26281 gtagacgtag ctctcgtacg gcctcacggc gggggtgccg gtcgccgcgg tggtgctggt
    26341 ggtcatcagg aggcccccgg ttccaggaag aaatgggcgt acggcacggt ccagacggcc
    26401 tcgtggccga gccggtggcc ggtgtagccg tcgtcgccgt atgccgtgcc gtggtcggag
    26461 cagacgatgg cgaagcaccg gcggcggctg ctcgcggcgg cgaagagccg gccgatgtgc
    26521 cggtcgacgt actccagggc ggccgcgtgg gtggcccggg agtcacccgc ttcg
//
