LOCUS       NZ_KB890945            31545 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces sp. CcalMP-8W B053DRAFT_scaffold_4.5, whole genome
            shotgun sequence.
ACCESSION   NZ_KB890945
VERSION     NZ_KB890945.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. CcalMP-8W
  ORGANISM  Streptomyces sp. CcalMP-8W
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 514328)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
REFERENCE   2  (bases 1 to 514328)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. CcalMP-8W
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 03:14:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,603
            CDSs (total)                      :: 6,529
            Genes (coding)                    :: 6,424
            CDSs (with protein)               :: 6,424
            Genes (RNA)                       :: 74
            rRNAs                             :: 6, 1 (5S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 35 of 105
            Pseudo Genes (incomplete)         :: 83 of 105
            Pseudo Genes (internal stop)      :: 5 of 105
            Pseudo Genes (multiple problems)  :: 18 of 105
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:04:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 31545
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB890945.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405361
            Source DNA and Organism available from Cameron  Currie
            (currie@bact.wisc.edu)
            Source DNA available from Cameron  Currie (currie@bact.wisc.edu)
            Organism available from Cameron  Currie (currie@bact.wisc.edu)
            Contacts: Cameron  Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31545
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..31545
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="interleaved"
                     /product="arylpolyene"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..31545
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[10408:11545](+)"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10409..11545
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     protocluster    1..30412
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[8396:10412](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      8397..10412
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     gene            <1..83
                     /locus_tag="B053_RS1000000137675"
                     /pseudo=""
     CDS             <5..83
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019524936.1"
                     /locus_tag="B053_RS1000000137675"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="XRE family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="FQDGGNRAAGLSDITLNDIDYLDLNY"
     gene            complement(156..836)
                     /locus_tag="B053_RS1000000136985"
     CDS             complement(156..836)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B053_RS1000000136985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158690059.1"
                     /transl_table=11
                     /translation="MKLEIASSHRRYSLHADLLAEGRVEITVVVCTTDGVIRGELTGEL
                     DACDLSEVGRLVASAPVASAPVASAVKTTSSAASAAPAKVTRHGQAWTPEATTYLEEQY
                     RAGKSPESLAEELGRSEKSIRWKLYGLKLVPYPGDLVPDPRPAPEPEVPKAYTVEAKRQ
                     LYPNAYKPWEPEDEQRLATRCAQGVSLSVLAQEFGRNEGAIASRLLKIRAEGPAADDAW
                     EYGG"
     misc_feature    799..816
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.21"
                     /tool="antismash"
     misc_feature    complement(1401..1415)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     misc_feature    complement(1451..1466)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.58"
                     /tool="antismash"
     misc_feature    1482..1498
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.06"
                     /tool="antismash"
     gene            1614..1844
                     /locus_tag="B053_RS0123515"
     CDS             1614..1844
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766100.1"
                     /locus_tag="B053_RS0123515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018491032.1"
                     /transl_table=11
                     /translation="MIRRIAITLAAVAAAGFVAAAPASASGWDGHAGGGHAGIEGGWAI
                     GEYQNLGGPYGITTIKGQAAYFDAERGWMVR"
     gene            complement(2250..4115)
                     /gene="asnB"
                     /locus_tag="B053_RS0123520"
     CDS             complement(2250..4115)
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612406.1"
                     /locus_tag="B053_RS0123520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_026238055.1"
                     /sec_met_domain="GATase_7 (E-value: 2.2e-45, bitscore:
                     148.3, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 5.9e-89, bitscore:
                     293.8, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGTAGWVSFDPEAPVTAPVADAMTATMACRGPDAHGLWLGGPVA
                     LGHRRLSVIDPAGGSQPMVFEENGTPVVAVSYTGEVFNYRELRRQLQVRGHGFRTESDT
                     EVVLHAYLEWGEAFTEHLNGMYAFALWDARTEELLLVRDRLGIKPLYYHPLPGGVLFGS
                     EPKAILAHHSVRPAIDTEGFAELVGFTKTPGHAVYKGMYELRPGHTLRVGRGGHTLRRY
                     WAVESHEHTDDLDTTIGRVRELLEDIVARQLVADVPVGSLLSGGLDSSIITALAARHRA
                     AEGAPPIRSFALDFDGHGDGFRADDWRGTPDAPFAELLARHVGSDHRTVTLSPGQLLGR
                     EAREAIMRARDLPFDLGDGDTSLYLLFQEVRRHCTVALSGEAADEVFGGYRWFNHPDTV
                     AADTFPWLAPPFGTGISGPGSGPGESLIDPALLAKIDLPGYRAQRYHEALAEVPRLTGE
                     SATDRRMREIGYLHLTRFLPWMLDRKDRASMAVGLEVRVPFCDHRLVSYVFNTPWSMKS
                     FDGREKSLLRAATRDLLPAEIADRVKAPYPTSRDRRYLEGLRTALKRATEGPDAPVREL
                     LDESALAAATADDPRPGYRTGTELVLALDFWLRGQNVGLGVDLEL"
     gene            complement(4152..5624)
                     /locus_tag="B053_RS0123525"
     CDS             complement(4152..5624)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612407.1"
                     /locus_tag="B053_RS0123525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_018491034.1"
                     /transl_table=11
                     /translation="MTTLHEPNEPDTAAPPLLRRTGPVLLVLLSAMFFAQFDFFVVNVA
                     APSLESSINADAAALELIVGGYAFAYAGGMITAGRLGDRYGHRLLFIIGTLAFGFTSLL
                     CGLAVTPGQLIAARLAQGLAGAVMVPPVLAVITAYFPNEKKGKAMAWYGAAAGLGSIAG
                     QVLGGALISADFAGLGWRTIFLINVPFCLVIAFAALRVLPAHVSRIRAGLDPVGAVGVS
                     FALALLLVPLTMGHVSGWPAWTWVSMALAVPVMMATLWWERALEARGGNPVLVLSLFRS
                     DSFRGGVIAGAAFMLYFGSFMFTLTLLLQSGLNLDPFEAGLMFSPMGVLFTATSMIGGR
                     LTARWGMNALVVAGGVTALGLALLAVPLAVSDSAVGLPWVVFCLCLIGAGNGVVLPALF
                     GAALINVPPQDAGTASGILTTTQQFASAAGVAAIGALFFTVAGNRPTTADWSLAMAWAT
                     AASFLLVLVVMWTTWTFKRFSPPPAKRSAAKA"
     misc_feature    complement(5764..5775)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            complement(5818..6270)
                     /locus_tag="B053_RS0123530"
     CDS             complement(5818..6270)
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1144: thioesterase superfamily protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612408.1"
                     /locus_tag="B053_RS0123530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hotdog fold thioesterase"
                     /protein_id="WP_018491035.1"
                     /transl_table=11
                     /translation="MTTFAAPPAPEAGPEAAAAWVNEAGSDTLAGRMGLTFLEAAPRRV
                     VATMPVTGNTQLQRMLHGGASAVLAESLGSLGAALHAGEGRIAVGVDINATHHLPVRSG
                     TVTGVATALHLGGSTASYEVVITDEAGRRVCTARITCAIHGRRKRG"
     gene            complement(6267..7982)
                     /locus_tag="B053_RS0123535"
     CDS             complement(6267..7982)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (58-444). E-value: 9.1e-45.
                     Score: 144.8. Matches aSDomain:
                     nrpspksdomains_B053_RS0123535_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612409.1"
                     /locus_tag="B053_RS0123535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_018491036.1"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-45, bitscore:
                     150.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLTSTPLLSPEARLRLAELPGLGGGNAWRIAAETNPAADLPVLL
                     ADRPLAGPDGTLRREFSLRELDALADAWSAWYLDRGVGPRDRVSVYLEDTFAYQVHLTA
                     LARIGAIGVLINGRMRPELALGLVRRTGSAGLFTDGERLALLAGRERELPELRWTALDE
                     EAGTLGARAPKPSQLYRHTDDDPVVICHSSGTTGNPKPVVWAHRQSVAGARFRLVNHPE
                     QEGTLVLAGAPQSHSSAIAFTFYSLLAGVPTIGWSDPTGPGIARGCATHRPNVVLAFNE
                     ALSHLATHEPEPADFDSVAVWVNLGDCGHDAHMRRLMRLGHTTAPDGTRTPGSIIDDGL
                     GSSELGWAALRRVLTADTPSRARHLGTRVPIGEVAVLREDGTEAAADEVGLLGVRSEAL
                     AHGYWNDSDTTYRTMLAGYWLSGDLVRRSADGEFFHVDRAVDRIRTETGDGYSALMEEE
                     LLLAVEELADCSVVAARDRGRTVPAAIVTLRRETTAEDLLRRANAALDRAGQPRLALLE
                     IAPTPEAIPLGPTGKVLKRQLRERYAALEEYRPADPQAVAVTTTADHGSTEALA"
     aSDomain        complement(6651..7808)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B053_RS0123535_AMP-binding.1"
                     /evalue="9.10E-45"
                     /label="B053_RS0123535_AMP-binding.1"
                     /locus_tag="B053_RS0123535"
                     /protein_end="444"
                     /protein_start="58"
                     /score="144.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="REFSLRELDALADAWSAWYLDRGVGPRDRVSVYLEDTFAYQVHLT
                     ALARIGAIGVLINGRMRPELALGLVRRTGSAGLFTDGERLALLAGRERELPELRWTALD
                     EEAGTLGARAPKPSQLYRHTDDDPVVICHSSGTTGNPKPVVWAHRQSVAGARFRLVNHP
                     EQEGTLVLAGAPQSHSSAIAFTFYSLLAGVPTIGWSDPTGPGIARGCATHRPNVVLAFN
                     EALSHLATHEPEPADFDSVAVWVNLGDCGHDAHMRRLMRLGHTTAPDGTRTPGSIIDDG
                     LGSSELGWAALRRVLTADTPSRARHLGTRVPIGEVAVLREDGTEAAADEVGLLGVRSEA
                     LAHGYWNDSDTTYRTMLAGYWLSGDLVRRSADGEFFHVDRAVDRIR"
     CDS_motif       complement(7365..7418)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B053_RS0123535_0001"
                     /evalue="1.20E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="B053_RS0123535"
                     /protein_end="206"
                     /protein_start="188"
                     /score="11.9"
                     /tool="antismash"
                     /translation="ICHSSGTTGNPKPVVWAH"
     gene            8397..10412
                     /locus_tag="B053_RS0123540"
     CDS             8397..10412
                     /NRPS_PKS="Domain: PP-binding (10-68). E-value: 2.5e-09.
                     Score: 29.3. Matches aSDomain:
                     nrpspksdomains_B053_RS0123540_PP-binding.1"
                     /NRPS_PKS="Domain: AMP-binding (183-574). E-value: 8.4e-79.
                     Score: 257.0. Matches aSDomain:
                     nrpspksdomains_B053_RS0123540_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612410.1"
                     /locus_tag="B053_RS0123540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AMP-binding protein"
                     /protein_id="WP_234018030.1"
                     /sec_met_domain="PP-binding (E-value: 5e-08, bitscore:
                     28.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-83, bitscore:
                     275.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSERISDAVERVRHIVASVLELDLVEVTAGASFQHDLKMDSLEK
                     VEFAARVEWAFGVALSDEEASGIDSARAAAVLLESRLPPAAGAGGTVPGAGVTVPEAAR
                     SAGVRTAPSPPVAAPAGPSALSSPRPAPRSPRPAGRPEAPYAGPGASASAVRPGGAPVS
                     AGIDRGAGIDLVDRLVGRHLAAGHGGRTAYLDPGLGAVSYRELYEAARGYAGALLAHGV
                     APGARALVVAEDSVATVAAVLGLWWHGCVPVPVSPMLGEANLAPVAADCAAEVVHLDTE
                     PAVPPAAAVLLTGDAVRAGIRTGGPNAANRPDLARPSTGHRPGQTALIQYTSGSTGRPK
                     GVRHATSAITAMLDGFGCLLALGADDIVLSTARMSFGYGFGSSVLCTLDAGATAALIGG
                     AVDLHSVRAALRRHRPTVLCSVPRLYAALLDTLRPGDEAVAALRLCLTAGENCPADLNH
                     RIQDVFGAPVMNCLGATEVMHVVVATPPDRPMPGRAGLAVPGTTATVRDGHGRPVPDGT
                     EGRLHIAGPTVALGYLDRPDDDRTTFTDGGAYTGDLVRRAADGTLTHLCRADDILNLGG
                     YKVPPAEIEAVLRTVPGLRDCAVVGGLDADGLECAVAFVVPDSWADEETIRRTLRATVR
                     ADLALYKRPARVEFVDALPSTATGKVAAYRLREQAS"
     aSDomain        8427..8600
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B053_RS0123540_PP-binding.1"
                     /evalue="2.50E-09"
                     /label="B053_RS0123540_PP-binding.1"
                     /locus_tag="B053_RS0123540"
                     /protein_end="68"
                     /protein_start="10"
                     /score="29.3"
                     /tool="antismash"
                     /translation="ERVRHIVASVLELDLVEVTAGASFQHDLKMDSLEKVEFAARVEWA
                     FGVALSDEEASGI"
     aSDomain        8946..10118
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B053_RS0123540_AMP-binding.1"
                     /evalue="8.40E-79"
                     /label="B053_RS0123540_AMP-binding.1"
                     /locus_tag="B053_RS0123540"
                     /protein_end="574"
                     /protein_start="183"
                     /score="257.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AAGHGGRTAYLDPGLGAVSYRELYEAARGYAGALLAHGVAPGARA
                     LVVAEDSVATVAAVLGLWWHGCVPVPVSPMLGEANLAPVAADCAAEVVHLDTEPAVPPA
                     AAVLLTGDAVRAGIRTGGPNAANRPDLARPSTGHRPGQTALIQYTSGSTGRPKGVRHAT
                     SAITAMLDGFGCLLALGADDIVLSTARMSFGYGFGSSVLCTLDAGATAALIGGAVDLHS
                     VRAALRRHRPTVLCSVPRLYAALLDTLRPGDEAVAALRLCLTAGENCPADLNHRIQDVF
                     GAPVMNCLGATEVMHVVVATPPDRPMPGRAGLAVPGTTATVRDGHGRPVPDGTEGRLHI
                     AGPTVALGYLDRPDDDRTTFTDGGAYTGDLVRRAADGTLTHLCRADDILNL"
     CDS_motif       9375..9422
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B053_RS0123540_0001"
                     /evalue="1.10E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="B053_RS0123540"
                     /protein_end="342"
                     /protein_start="326"
                     /score="21.1"
                     /tool="antismash"
                     /translation="ALIQYTSGSTGRPKGV"
     CDS_motif       9936..10022
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B053_RS0123540_0002"
                     /evalue="8.10E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="B053_RS0123540"
                     /protein_end="542"
                     /protein_start="513"
                     /score="31.0"
                     /tool="antismash"
                     /translation="PDGTEGRLHIAGPTVALGYLDRPDDDRTT"
     CDS_motif       10089..10151
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B053_RS0123540_0003"
                     /evalue="1.50E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="B053_RS0123540"
                     /protein_end="585"
                     /protein_start="564"
                     /score="11.4"
                     /tool="antismash"
                     /translation="LCRADDILNLGGYKVPPAEIE"
     gene            10409..11545
                     /locus_tag="B053_RS0123545"
     CDS             10409..11545
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (134-377). E-value:
                     6.2e-44. Score: 142.5. Matches aSDomain:
                     nrpspksdomains_B053_RS0123545_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612411.1"
                     /locus_tag="B053_RS0123545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl synthase N-terminal-like
                     domain-containing protein"
                     /protein_id="WP_018491038.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.4e-22, bitscore:
                     73.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="APE_KS2 (E-value: 1.5e-47, bitscore:
                     157.1, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWDITGMGAVACNGTTPSEVFDSLCAGRDGRGPLQVFDHEKYRA
                     RNAYEISDRALPGVDEPGRATRWLVDAIDQALADAGHPRDLTDVPVLVGTTLQEQRSAE
                     LWWRHGSALDPADLHFGTALREEYGAARTYTFANACAASLYALAMATDLIELGEADTVV
                     VAGTDAIGESAFGTLDRVQNDVPDALRPFDRSHRGMLMGEGAVAVVLTRAAAPGRPVHA
                     RLRGVGVNCDAQHSTAPDPEGITRVLRDAYRLAGAAPEEIDLVMLHGSGTPKNDSTEAT
                     VLSRIFPPGGGPLMTAVKSMTGHTLGGSGLLSLTTAVLALQRGQVPPVLGLTDPIEEAA
                     GLRLVREHAAAAPELTLAQVDAFGFGGINAAAILEAAR"
     aSDomain        10811..11539
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B053_RS0123545_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="6.20E-44"
                     /label="B053_RS0123545_PKS_KS.1"
                     /locus_tag="B053_RS0123545"
                     /protein_end="377"
                     /protein_start="134"
                     /score="142.5"
                     /tool="antismash"
                     /translation="TFANACAASLYALAMATDLIELGEADTVVVAGTDAIGESAFGTLD
                     RVQNDVPDALRPFDRSHRGMLMGEGAVAVVLTRAAAPGRPVHARLRGVGVNCDAQHSTA
                     PDPEGITRVLRDAYRLAGAAPEEIDLVMLHGSGTPKNDSTEATVLSRIFPPGGGPLMTA
                     VKSMTGHTLGGSGLLSLTTAVLALQRGQVPPVLGLTDPIEEAAGLRLVREHAAAAPELT
                     LAQVDAFGFGGINAAAILEAA"
     gene            11542..12498
                     /locus_tag="B053_RS0123550"
     CDS             11542..12498
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612412.1"
                     /locus_tag="B053_RS0123550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl synthase N-terminal-like
                     domain-containing protein"
                     /protein_id="WP_026238056.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 5.2e-19, bitscore:
                     63.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAHPAAPSSPRVAVVTGAGLAVPGLTLPDELLGTVREGGFDPA
                     TGLVGRDLRHKDRASRLALRATAPALRDAGLFDGDRYTGPGDSTAVVVSTNVGILENVC
                     SFADTIARDTVLGLSPLGLPQTSSNVIAGSVAMAHGLRGPNVTLCNGPTSGLDALYWAR
                     ALIVTGRADTAVVIGVEPAGEIVTKLLGTPALDGAVALVLESADRAAGRGAGIRATVAG
                     CAREADLARAVARAGGLTPDLWLTEAADDPAGPPADSVLDPAAGLGAASGALGVLQAAA
                     AVAHLDAHGGHTVLATCGGPEGDGVAAVFLTGPDHTP"
     gene            12529..12798
                     /locus_tag="B053_RS0123555"
     CDS             12529..12798
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (11-73). E-value: 3.3e-15.
                     Score: 48.1. Matches aSDomain:
                     nrpspksdomains_B053_RS0123555_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612413.1"
                     /locus_tag="B053_RS0123555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl carrier protein"
                     /protein_id="WP_018491040.1"
                     /sec_met_domain="PP-binding (E-value: 1.4e-13, bitscore:
                     45.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARTDQAFDAEELRTVVAEALELPLDEVTDDARFKEDLEVDSLI
                     SLEIAVRVEERYGVKIDESRLAEIGSFRLVRELIEAELNGASAT"
     misc_feature    complement(12542..12557)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.89"
                     /tool="antismash"
     aSDomain        12562..12747
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B053_RS0123555_PP-binding.1"
                     /evalue="3.30E-15"
                     /label="B053_RS0123555_PP-binding.1"
                     /locus_tag="B053_RS0123555"
                     /protein_end="73"
                     /protein_start="11"
                     /score="48.1"
                     /tool="antismash"
                     /translation="EELRTVVAEALELPLDEVTDDARFKEDLEVDSLISLEIAVRVEER
                     YGVKIDESRLAEIGSFR"
     gene            12795..13565
                     /gene="fabG"
                     /locus_tag="B053_RS0123560"
     CDS             12795..13565
                     /EC_number="1.1.1.100"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (15-182). E-value: 8.2e-28.
                     Score: 89.5. Matches aSDomain:
                     nrpspksdomains_B053_RS0123560_PKS_KR.1"
                     /codon_start=1
                     /gene="fabG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767232.1"
                     /locus_tag="B053_RS0123560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="WP_018491041.1"
                     /sec_met_domain="adh_short (E-value: 8.8e-44, bitscore:
                     144.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.4e-32, bitscore:
                     108.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGTGTTGGEASARPVALVTGGSRGIGRAVVARLAEDGYDIAFCY
                     RSDAEAAAEAALIAEKAGARVLHRPVDVSDAEQVRGFVSAAEEELGPLTAVVTSAGITR
                     DRPLALMAEDEWRSVMDTNLDGTYNVCRAAVYPLMRRRRGAVVTLSSIAGVHGSAGQTN
                     YAASKAGIIGFTRSLARECGRYGIRANVVAPGLISTDMTASLPADVAERHLKSIPLARA
                     GTPQEVADLVSFLVSDRAAYITGQVVEINGGLPS"
     aSDomain        12840..13340
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B053_RS0123560_PKS_KR.1"
                     /evalue="8.20E-28"
                     /label="B053_RS0123560_PKS_KR.1"
                     /locus_tag="B053_RS0123560"
                     /protein_end="182"
                     /protein_start="15"
                     /score="89.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGGSRGIGRAVVARLAEDGYDIAFCYRSDAEAAAEAALIAE
                     KAGARVLHRPVDVSDAEQVRGFVSAAEEELGPLTAVVTSAGITRDRPLALMAEDEWRSV
                     MDTNLDGTYNVCRAAVYPLMRRRRGAVVTLSSIAGVHGSAGQTNYAASKAGIIGFTRSL
                     AREC"
     CDS_motif       12846..12908
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B053_RS0123560_0001"
                     /evalue="3.10E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="B053_RS0123560"
                     /protein_end="38"
                     /protein_start="17"
                     /score="16.6"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVVARLAEDG"
     CDS_motif       13233..13292
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B053_RS0123560_0002"
                     /evalue="7.60E-08"
                     /label="PKSI-KR_m4"
                     /locus_tag="B053_RS0123560"
                     /protein_end="166"
                     /protein_start="146"
                     /score="24.9"
                     /tool="antismash"
                     /translation="VTLSSIAGVHGSAGQTNYAA"
     gene            13799..14119
                     /locus_tag="B053_RS0123565"
     CDS             13799..14119
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767233.1"
                     /locus_tag="B053_RS0123565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018491042.1"
                     /transl_table=11
                     /translation="MARKDRTTDTTGEKDSERWMARFQVRLAMRPGVDRAVVLQAVKEV
                     TAHCAETGEHPQTRFGDPDAYAVEAAARLVPADRGARAERHNGVLRSVESVVRKIRDVP
                     GL"
     gene            complement(14228..15775)
                     /locus_tag="B053_RS0123570"
     CDS             complement(14228..15775)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137822.1"
                     /locus_tag="B053_RS0123570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4041 domain-containing protein"
                     /protein_id="WP_234018031.1"
                     /transl_table=11
                     /translation="MSGLRFNPPPNWLLPEGWVPPEDWRPDPSWPPPPPGWQLWLADPP
                     EAPPTTGAVPHQYAPAPEAPAGRKRGWFGRRRHDGTSELEELRAWIARAHGADAAQVAG
                     LVYRTRQEAAVLLTQAGEQAEAIVEEARQSVRDTRSEAKQVAKDTEKTRKEAERHRREI
                     YQAESRLTELRAQLVTTDETVLLQQAGIYAYHHQLHDAVAYRTRLDSLKAEIKDLARTN
                     RAVLAATDWTVNGSAREGRRMIRDFSKLMLRAYNAEADYAVRTMRPHRLTSLVDRLYKS
                     RETIARLGATMHIRISDAYHDARVRELRLTADFLQKKDEEKEAQREARAREREEAAAQR
                     ELDREREKLNKEVNHYEAALERLRSQGDHDAVRDMEAKLAELQQALQDVDARAANVRTG
                     YVYVVSNIGAFGDSIVKIGMTRRLEPLDRVYELSGAAVPFRFDVHALIFSKDAVGLETR
                     LHQEFADRRVNRVNSRKEFFHVTPAEVRTALERFGGEHLVEFSETPQALEWRASSRG"
     gene            16190..16411
                     /locus_tag="B053_RS0123575"
     CDS             16190..16411
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268844.1"
                     /locus_tag="B053_RS0123575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018491044.1"
                     /transl_table=11
                     /translation="MERPLLPLRSALVFLMAVISGITAGCLCWIAGEGVARGVLAGLAV
                     VGLSVPFFDRLIAPEAAGDTREEVQDHG"
     misc_feature    16202..16204
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16404..17513
                     /locus_tag="B053_RS0123580"
     CDS             16404..17513
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767235.1"
                     /locus_tag="B053_RS0123580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator"
                     /protein_id="WP_018491045.1"
                     /transl_table=11
                     /translation="MGELRPLGEDLTQESRALAQALRELFEGLDVSVRRYAARHRRDPG
                     TFSRYLNGTRLPPWEVIMGIMTDLAEHRGTTVTPEAIEFIRGLHGSAFDSSSSPKHAVE
                     IIEQQLADADHVSRRSSVRGDILGDALLERQNRIANLEVRLSQMEAALTAERERAGQLA
                     AAHPDVSELRGERDVLRQEVTRLGDELQAAHEQRDAAEARCDLLERQLAAVEHPVALPA
                     APPLRMPKVLVVDDQPDNLLAMAAVLETLDQELVTVSSGRDALKALLLHDDFAVIIMDV
                     QMPEMDGYETAAHIKRRPRNRDVPIIFLTAMGVDPEHTARGYAAGAVDYISKPFDPWAL
                     RAKVAVFTEIHLERRIGPSEGTASRPSSA"
     gene            complement(17521..18363)
                     /locus_tag="B053_RS0123585"
     CDS             complement(17521..18363)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158137.1"
                     /locus_tag="B053_RS0123585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_018491046.1"
                     /transl_table=11
                     /translation="MPSFDTPEPISVTAHVEAGSIRFTAGDGPRTVVDVRPRDPGRDQD
                     VTTAGRTEVTYASGALAVRTPRPGLLGRTGTVDVTVELPAGSRVEMTGAWAQVLGEGRL
                     GEVRVKTSSGDVRLDTVGPLHLTASHGSITVDRVEGPAEITTSSGSLRLGHVDGPAVLK
                     NSHGTTTVGVALDDLRVRGANGDIAVTRAEGSVTATAAHGTLLVSEVARGEVRLETSYG
                     AVEVGVRKGTAAWLDVSSGSGRVRNALTESQAPEDAEDTVKVHARTRHGNIDIRRAER"
     gene            complement(18454..18966)
                     /locus_tag="B053_RS0123590"
     CDS             complement(18454..18966)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018556798.1"
                     /locus_tag="B053_RS0123590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="toxin-antitoxin system HicB family antitoxin"
                     /protein_id="WP_018491047.1"
                     /transl_table=11
                     /translation="MDLTPYVDSLRRELAVAAEAGGDEARALADRLTAPLESATRLTML
                     HVLSAAMDEVTRELAPGSVDVRLRGLDPDFVVTVPQAGDGAPVQPAGPAEPARIPADGD
                     EGGTARVNLRLPAHLKARAEDAAAAEGLSVNAWLVRAVSAAVDGGTRLRTAGRAPTAGQ
                     SFTGWVR"
     misc_feature    18986..19002
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     misc_feature    19049..19064
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.99"
                     /tool="antismash"
     misc_feature    19054..19063
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.62"
                     /tool="antismash"
     misc_feature    19060..19075
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.49"
                     /tool="antismash"
     gene            19223..19792
                     /locus_tag="B053_RS0123595"
     CDS             19223..19792
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059277.1"
                     /locus_tag="B053_RS0123595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DoxX family membrane protein"
                     /protein_id="WP_026238058.1"
                     /transl_table=11
                     /translation="MTVLRRVARPLLASMFVSGGFTAVRDPQRLAPAAAPVADALSPAV
                     APRTSLLPEDPERLVRLNGAVQLGAGLLLALGRAPRLASAALAVTLVPTTLAAHRYWEI
                     EDPEERSAQRTHFLKNASLLGALLIAAADTHGKPSFAYRTRHAAAHASDTVAHRAHRAA
                     DLVGGATGGAVDSVTGAVEAARKRLP"
     gene            complement(19869..20360)
                     /locus_tag="B053_RS0123600"
     CDS             complement(19869..20360)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767238.1"
                     /locus_tag="B053_RS0123600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FBP domain-containing protein"
                     /protein_id="WP_018491049.1"
                     /transl_table=11
                     /translation="MRPLTEQEIRTAFVNCTKGEAKRLHVPRDLAERPWADLDFLGWRD
                     PQAPDRAYLVAAWGSRPVGLQLRSSDAGSWQTRRSMCSMCVTTHTGGVSLLVAPRAGKA
                     GQQGNSVGAYMCSDLACSLYVRGKKDAGIGARLHESLTLEEKVRRTVANLSAFIAKVTE
                     "
     misc_feature    20386..20403
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.49"
                     /tool="antismash"
     gene            20447..21019
                     /locus_tag="B053_RS0123605"
     CDS             20447..21019
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129486.1"
                     /locus_tag="B053_RS0123605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_018491050.1"
                     /transl_table=11
                     /translation="MAKAGPAAERVVRAGAELADEIGFEGVTPSALARQLGVRTASLYS
                     HVRNAHDLKTKIALLALEELADRASAALAGRAGKDALSAFADAYRDYAFQHPGRFAAAQ
                     FRLDADAAAASAGVRHSRMMRAILRGYDLTEQQQTHAVRLLGSVFSGYVGLEAAGGFSH
                     SAPASQESWTEILGALDALLRNWPSAT"
     gene            21150..22334
                     /locus_tag="B053_RS0123610"
     CDS             21150..22334
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548189.1"
                     /locus_tag="B053_RS0123610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_018491051.1"
                     /transl_table=11
                     /translation="MNTPHEWITTPIGPDILRGALDLERTDRGVLPHRLPAHARAQIPD
                     GQLAMAEAQPSGVRLAFRSRATTVELDVIATKRVYPGAPRRPDGVYELLVDGRHVGRAS
                     APDGDTLTIDLSSGASHARPGPVETLRFGGLPDAEKGIEIWLPHDETTQLVALRTDAPV
                     DVQRSGGRPVWLHHGSSISHGSNAATPTGTWPALAAAHSGAELINLGFSGSALLDPFTA
                     RALRDTPADLISIKIGINLVNTDLMRLRAFGPAVHGFLDTVREGHPTTPLLVISPIHCP
                     IHEHTPGPSTYDLGAMGEGRLRFTATGDPAETAAGKLTLTVIRDELARLVAGRTATDPH
                     LHHLDGLDLYGENDHADLPLPDDLHPDPATHRLIAERFARLAFGHDGPFAGTGH"
     gene            complement(22415..23032)
                     /locus_tag="B053_RS0123615"
     CDS             complement(22415..23032)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007820479.1"
                     /locus_tag="B053_RS0123615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF998 domain-containing protein"
                     /protein_id="WP_018491052.1"
                     /transl_table=11
                     /translation="MRSAPWWALLSSGCAPVLLVGSWAIAQQRQGPGYDPAKETLSVLA
                     AYGATSYWLMTGMLLVLGTCYVVTAHALWEAAPAGRLALAGGGLCALALTVVPAPSSGG
                     ALEHGAVAALGLVLLAVWPPLAAVRGREPVPWGLRPDVALGASALMGATALWSLAELQS
                     AGAPGVAERVVTFVQALWPFLVVVSCRRSAGSWRGGEARGRG"
     gene            complement(23162..23359)
                     /locus_tag="B053_RS0123620"
     CDS             complement(23162..23359)
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018515182.1"
                     /locus_tag="B053_RS0123620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferredoxin"
                     /protein_id="WP_026238059.1"
                     /transl_table=11
                     /translation="MGVQVDRERCVGAGMCALTAPDVFTQDDDGLSEVLPGRAETAGAH
                     PLVGEAVRACPVGAVALSAD"
     gene            complement(23365..24636)
                     /locus_tag="B053_RS0123625"
     CDS             complement(23365..24636)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606615.1"
                     /locus_tag="B053_RS0123625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_018491054.1"
                     /sec_met_domain="p450 (E-value: 5.1e-27, bitscore: 89.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTESTTDPTTRRTPGSAAPATAAAVDPAPATPFPQDRGCPYHPPA
                     GYAPLREGRPLARVALFDGRPVWAVTGHALARRLLADPRLSTDRTHPDFPAPAPRFANA
                     NRRRVALLGVDDPEHNTQRRMLIPAFSVKRINALRPRIQETVDRLLDAMERQGPPAELV
                     SAFALPVPSMVICALLGVPYADHEFFEERSRRLLRGPGADDVDRALDELEEYLGALIDR
                     KRTEPGDGLLDELIHRDHPGGPVDREELVSFAVILLIAGHETTANMISLGTFTLLRHPE
                     QLAALRAGGTTTAGAVEELLRFLSIADGLQRLATGDIEVPDAGVTIRKGEGVLFSTSLI
                     NRDDDVFPRPETLDWERPARHHLAFGFGVHQCLGQNLARAELDIAMRSLFERLPGLRLA
                     VPAREIPHKPGDTIQGMLELPVAW"
     gene            25064..25600
                     /locus_tag="B053_RS0123630"
     CDS             25064..25600
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767242.1"
                     /locus_tag="B053_RS0123630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018491055.1"
                     /transl_table=11
                     /translation="MDDLTRMWISTVPALDPESREVILGLDQASADPAERMVRLLLNRG
                     HEGEDGVFYLLPDDLAAWYERSGDRLAVTVSAHRDVLAHDLAAYGEELRDALDGLPRLA
                     SDGGEHVVLLRREIGTDFVPAEQDGEPQPVLLLDHVGGPAGPADPARLFESGEASIAVV
                     NAAWSPEGAAQHTPS"
     gene            25687..26307
                     /gene="thpR"
                     /locus_tag="B053_RS0123635"
     CDS             25687..26307
                     /GO_function="GO:0008664 - 2'-5'-RNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="thpR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606620.1"
                     /locus_tag="B053_RS0123635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="WP_026238060.1"
                     /transl_table=11
                     /translation="MNELPDAMTGPTVDEREQAATIRVFLALAPPDDAKDELERALGPA
                     YAAHPRLRWNRIEDWHITLAFLGELPPSSVPPLMSPLSGLAAGRRPLRLALRGGGHFDE
                     RVLWSGIDGDLEGLHRLATDVRGLVRACGVSFSERPLRPHLTLARSRRGDRGAAVEIAA
                     GLAAFSGRTWAAERLHLVGSNIGRGPGPIHYRDIEAWRFGHAA"
     gene            complement(26533..27381)
                     /locus_tag="B053_RS0123640"
     CDS             complement(26533..27381)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767245.1"
                     /locus_tag="B053_RS0123640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_018491057.1"
                     /transl_table=11
                     /translation="MTGGPPPRRDDLPEEPRRERLARTFDEDAELYDRARPGYPPRLYE
                     DLGRLAGAGPGSRVLEVGCGTGQATVPLAARGCRVTAVDAGPRMAALARRNLAGAGFGP
                     AEAEVVTARFEDWPLPGEPYDVLVSATAFHWIDPAVRLTRAADALRPGGALAVVRGQHV
                     RGGTEEFFVEVQRCYERFDPRTPPGLRPPAAADVDGSDHAREVAASGRFGPTVLRRYEQ
                     DITFTTSGYLDLLRTFSGHRALPDTARNGLLGCVEALIEGGYGGTVTKRYLIELAVSHR
                     R"
     gene            complement(27378..28004)
                     /locus_tag="B053_RS0123645"
     CDS             complement(27378..28004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606623.1"
                     /locus_tag="B053_RS0123645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018491058.1"
                     /transl_table=11
                     /translation="MDEATVIPTPARHDENFWSVVMAPVEPAWSEPGDDDTFEMDGKVL
                     DAARALAERISTRAHAYRTAGQPFDAALMAAPDLQLALLRSLYEARLSVDRLAESAATA
                     AGRGGASYTQLGAAWGGIRRQSARLKWPHAVVKRPADESIPLDYAGGAAVIHHDPGADA
                     WWYTATAADRQEEESEAAYGTSAEAIARATEFLLTHARPARQDTA"
     misc_feature    28041..28053
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            complement(28050..28574)
                     /locus_tag="B053_RS0123650"
     CDS             complement(28050..28574)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152349.1"
                     /locus_tag="B053_RS0123650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_018491059.1"
                     /transl_table=11
                     /translation="MKPASAPPPASTPAPDLADVPDAELLRLDHQVCFSLHAASRAFGG
                     FYRQALKGLGLTYPQYLVMLVLWEDGPRPVKAIGERLHLDSGTLSPLLKRLEAAGLVRR
                     ERSREDERSVVVELTGDGVRLRESALSIPRGVLAATGLSVEEVLALQETLGRLTVALGE
                     AVDIPDEPPKE"
     gene            28691..29101
                     /locus_tag="B053_RS0123655"
     CDS             28691..29101
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606625.1"
                     /locus_tag="B053_RS0123655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Ohr family peroxiredoxin"
                     /protein_id="WP_018491060.1"
                     /transl_table=11
                     /translation="MDALYTAAATANGREGRAVSSDGQLDLPLALPPALGGNGKGTNPE
                     QLFAAGYAACFASAMAAVAREMKVDTKDVSVTSEVSIGKDGDGFGLSVVMRVELPDSLT
                     GEVGQRLVEATHAYCPYSKATRGNIDVELVIE"
     gene            complement(29091..30626)
                     /locus_tag="B053_RS0123660"
     CDS             complement(29091..30626)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019761731.1"
                     /locus_tag="B053_RS0123660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_018491061.1"
                     /transl_table=11
                     /translation="MTVFILVAGAFTGPYVWRDTAAYLAAGGADVRTVALTGLGKGAGG
                     PAESVDLETHIADVLAVIDEVVARGGGDIVLVGHDYGIHPVLGAADRRVVAVARIVHLD
                     SGMPGDGVPALAAVPDQRLREELAEGGGGRTGGELPPPARDGWSRWGSTAGLSEAALDG
                     LTALAAPQPLGTLLQPLRLTGAVAEVPVTGVLCTGNGPGIELVQLMVDMGEPALQALAG
                     PRVTFFELPTGHWPMLSRPAELAGVLTEAAAGGGHRLTAPGTGGPPPHLRPFLLDVPER
                     PRERTGNTDLYLPEGPGPHPAVVFVHGGPVPVDARPTPRDWPTLTGYARYVAGRGAASA
                     VLDHRLHAVTDYGRAAEDVADAVERVRADPRVDGDRVALWFFSGGGPLTADWLAAPPPW
                     LRCLALNYPVLAPLPSWGVTDARFRPVRAVARAGRLPIVLVRAGREMPEIAATVEEFLT
                     AAARGGADVEVVDVPAGRHGFETLDRTAASREAVHRAVTAVLERLERGGPTTR"
     misc_feature    complement(31281..31292)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
ORIGIN
        1 acttccagga cggcggaaac cgagcggcag gactctccga catcaccctc aacgacatcg
       61 actacctcga cctcaactac taaccccaac aaccaaccaa caccacaacc cgcctaccac
      121 cacaacccgc cccgccccac accaccacaa cccgcctacc caccgtactc ccaggcatca
      181 tccgccgccg gaccttccgc tcggatcttc agcaaccgag aagcgatagc gccttcattg
      241 cgaccgaatt cttgcgccag caccgacaga gagacacctt gagcacagcg ggtggcaagc
      301 cgctgttcgt cctcaggctc ccagggtttg tacgcgttgg ggtacagctg tcgctttgcc
      361 tccacggtgt acgccttggg tacttccggc tcaggggcag ggcgcggatc gggcacgagg
      421 tcgccggggt agggcacgag tttgaggccg tacagcttcc agcggatgga tttctcgctg
      481 cgcccgagtt cctccgccag gctctccggg ctcttacccg ctcggtactg ctcttcaagg
      541 taggtggtgg cttcgggagt ccaagcctgc ccgtggcggg tgactttggc gggggcggca
      601 gaagcagcag atgaagtggt cttcacagcg gaggcgacgg gagcggaggc gacgggagcg
      661 gaggcgacaa gacggccgac ttcgctgagg tcgcatgcgt ccagctctcc agtcagttcg
      721 ccgcggatga ctccgtcagt ggtacagacg acgacagtga tctcgacacg cccctctgcc
      781 aaaaggtcgg cgtggaggct gtaacggcgg tgtgaactgg cgatctcaag cttcacgact
      841 gcggcgttcc gtgatgcgtc agaggctgcg gacacatggc ggtaggccgg agacagcagt
      901 tcatgaacgt gccgggtagc caggaaggcg tcaccgtcat cgagtcggta gcgtgtatgg
      961 cccgcctcca catcgcacgt tgcgtacaag acctcgagct gttgaccatc gaaccgacca
     1021 ggatctcggc ccggggcagt agtggggagg gtgagcggac cacgacctgg ccggagctct
     1081 cgaatgacag cgtcggggtc gccgtaccaa gtgccaccgg catcacgaaa agcgtagatc
     1141 agcacaacag acagcccttc attcacatga gacatcagca aatgatggcg cggccgacaa
     1201 cagggtcacc tcaaaccggc caaactccgc tcgctcccgc tctcccccac accaggccgc
     1261 ccctcacccg tacccacgaa ccgacccgcc tgccagaccc cgcaaacctc accgacgcgc
     1321 cgcctcgagc cctacgccaa gaatcggctc acgtaactgc atcacgcccg acacctcgct
     1381 gcactccccc tcaaaagggc atggacagga gtaatcagtg tgtggccggt cgcactctgc
     1441 gcctcggagg gtgaaggaat ggtcagtcgg tctcaagggc gttccccgtc cggggtatcg
     1501 cagccaatcg ggttctctac gccgatgtct ccgcgcgccg cgtgcgccgc agatgggtcg
     1561 gctggtcaag gtggcttcgc aggcatatgc cgctaactcg aaggagagcg ttcatgattc
     1621 gtcgtatcgc gatcaccctg gcagctgtcg ccgcggccgg tttcgtcgcc gcggccccgg
     1681 cttccgcgag tggctgggac ggccatgccg gtggcggcca cgcgggcatc gagggcggct
     1741 gggccatcgg tgagtaccag aacctgggtg gcccgtacgg aatcaccacc atcaagggtc
     1801 aggcagcgta cttcgacgcg gagcgcgggt ggatggtccg ctgacctcgg gagccggggg
     1861 cacgcaaccg cgtagttccg gatgagggtg aggggcctgt gccgtcgtgg cgcaggcccc
     1921 tcgctcatgt cgtcaccaac cggtcagcgc ccggggattc gaggaaagcg aggcgatacg
     1981 cgggcagttg cccgggcggg ggacctcttc gcgcgagcgg cgagatctca ccggcccggc
     2041 cccggatcac cgcccagtac cccgtaccgg cgccaggact ccggtgcgac gtggacggaa
     2101 ccgtccgtcg tggagagtcg tcggcggagc gtggccgtcc cggatcggac ctggggcctg
     2161 gggtccaggg gcctgacggt gcagttcgtc gtgcgtgttc gtccgggtcg gtgcgggcgc
     2221 ggggccgtgg gtcctcttcc cgatgcggtt cagagttcca ggtcgacgcc gaggccgacg
     2281 ttctggcccc gcagccagaa gtcgagggcc agcaccagtt cggtcccggt gcggtagccg
     2341 ggccgcgggt cgtcggcggt ggcggcggcg agggcggact cgtccaggag ttcgcgtacc
     2401 ggggcgtcgg ggccctcggt ggcgcgcttg agtgcggtcc gcaggccttc gaggtagcgc
     2461 cggtcccggc tggtcgggta aggggccttc acccggtcgg cgatctccgc ggggagcagg
     2521 tcgcgggtgg cggcgcgcag gagactcttc tcccggccgt cgaacgactt catcgaccac
     2581 ggggtgttga agacgtaact caccagccgg tggtcgcaga acggcacacg tacctccagg
     2641 ccgacggcca tgctggcccg gtccttgcgg tccagcatcc agggcaggaa ccgggtgagg
     2701 tggaggtagc cgatctcgcg catccgccgg tcggtggcgg actccccggt caggcggggg
     2761 acctcggcga gcgcctcgtg gtagcgctgg gcccggtagc ccgggaggtc gatcttggcc
     2821 aggagggccg ggtcgatcag ggactcgccg gggccgctgc cggggccgga gatgccggtg
     2881 ccgaacggtg gcgcgagcca ggggaaggtg tcggcggcga cggtgtcggg gtggttgaac
     2941 cagcggtagc cgccgaacac ctcgtcggcc gcctcgccgg acagggcgac cgtgcagtgc
     3001 cggcggacct cctggaagag caggtagagc gaggtgtcgc cgtcgccgag gtcgaagggc
     3061 aggtcgcggg cgcgcatgat cgcctcgcgg gcctcccggc cgaggagctg tccgggggaa
     3121 agggtgacgg tccggtggtc ggagccgacg tgccgggcga gcagttcggc gaacggtgcg
     3181 tcgggggtgc cgcgccagtc gtcggcccgg aagccgtcgc cgtggccgtc gaagtcgagg
     3241 gcgaaggacc ggatcggcgg ggctccctcg gcggcccggt ggcgggcggc gagggcggtg
     3301 atgatgctgg agtccagtcc gccggagagc agcgagccca ccgggacgtc ggccaccagt
     3361 tgccgggcga cgatgtcctc cagcagttca cggacgcggc cgatggtggt gtcgaggtcg
     3421 tcggtgtgct cgtgggactc caccgcccag tagcggcgca gggtgtggcc gccgcgcccg
     3481 acgcgcaggg tgtggccggg gcgcagctcg tacatgccct tgtagacggc gtggccgggg
     3541 gtcttggtga agccgaccag ttcggcgaag ccctcggtgt cgatcgcggg ccgtaccgag
     3601 tggtgggcca ggatcgcctt gggctcggag ccgaacagga cgccgccggg gagcgggtgg
     3661 tagtagagcg gcttgatccc cagccggtcg cggaccagca ggagttcttc ggtgcgggcg
     3721 tcccacaggg cgaaggcgta catgccgttg aggtgctcgg tgaaggcctc gccccactcc
     3781 aggtaggcgt gcaggacgac ctcggtgtcg ctctcggtgc ggaagccgtg tccgcggacc
     3841 tgcaactgcc tccgcagctc gcggtagttg aagacttcac cggtgtagct gacggctacg
     3901 accggcgtgc cgttctcctc gaacaccatg ggctggctgc cgcccgccgg gtcgatgacg
     3961 gagagccggc ggtggccgag ggcgacgggc ccgccgagcc agaggccgtg cgcgtccggc
     4021 ccccggcacg ccatggtcgc ggtcatcgcg tcggccaccg gggccgtgac cggggcttcc
     4081 gggtcgaagg agacccatcc tgctgttccg cacatgttga tgtggcctct ctcgacgtgg
     4141 tgggacgggg gtcaggcctt tgcggcggac cgcttggccg ggggtgggct gaagcgcttg
     4201 aacgtccagg tcgtccacat cacgacgagg acgagcagga agctcgcggc ggtcgcccag
     4261 gccatcgcga gggaccagtc ggccgtggtg ggccggttgc ccgccaccgt gaagaacagc
     4321 gcgccgatcg ccgcgactcc ggccgcgctg gcgaactgct gggtggtggt gaggatgccg
     4381 gaggccgtcc cggcgtcctg cggggggacg ttgatgagcg cggcgccgaa cagtgcgggc
     4441 agcacgacac cgttgcccgc gccgatcagg cagaggcaga acaccaccca gggcaggccg
     4501 accgcggagt ccgacacggc cagcggcacg gccagcagcg ccagtccgag cgcggtcacc
     4561 cctccggcga ccaccagggc gttcatgccc cagcgtgccg tcagccggcc gccgatcatc
     4621 gaggtggcgg tgaacagcac acccatcggc gagaacatca gtccggcctc gaacgggtcc
     4681 aggttcagcc cggactgcag gagcagcgtc agggtgaaca tgaaactgcc gaagtagagc
     4741 atgaacgcgg cgcccgcgat caccccgccg cggaaggaat cgctgcggaa cagggacagc
     4801 acgagcaccg gattgccgcc gcgggcctcc agggcccgct cccaccacag cgtcgccatc
     4861 atgacgggaa cggccagggc catgctgacc caggtccagg ccggccagcc ggagacgtgc
     4921 cccatggtca gcggaaccag cagcagggcg agcgcgaacg agacgccgac cgcgccgacc
     4981 gggtcgagac ccgcccggat ccggctgacg tgcgcgggga gcacccgaag ggcggcgaag
     5041 gcgatgacca ggcagaacgg cacgttgatc aggaagatgg tgcgccagcc gagtccggcg
     5101 aagtcggccg agatcagcgc accgccgaga acctggcccg cgatggaccc cagaccggcg
     5161 gcggcgccgt accaggccat cgccttcccc ttcttctcgt tggggaagta cgcggtgatg
     5221 acggccagca cgggcggcac catgaccgca ccggccagtc cctgggccag acgggcggcg
     5281 atcagctgcc cgggggtgac ggccagtccg cacagcagcg aggtgaaccc gaaggcgagt
     5341 gtgccgatga tgaacagcag gcggtgcccg tagcggtcac ccagccggcc ggcggtgatc
     5401 atccctcccg cgtacgcgaa cgcgtagccc ccgacgatga gttccagcgc ggccgcgtcg
     5461 gcgttgatgc tgctctccag cgagggagcc gccacgttca ccacgaagaa gtcgaactgg
     5521 gcgaagaaca tcgccgacag caggacgagc agcaccggcc cggtgcgccg caggagggga
     5581 ggagcggccg tgtccggctc gttcggttcg tgaagcgtgg tcatggcact cctcggggcc
     5641 ggtgcggccc ggcggctgtg acggacgggg aagaaggggc actgcgttgc tcgggacgga
     5701 gagaggggct cgggaggggc gggggtgttc acgggggtgc gcggcgttgt cgggatgtgc
     5761 gcggcgttcc cgtacgggag tggggtgggg ccgggcgcct tcggtcggga gcgccggtca
     5821 gccgcgcttc cgcctcccgt ggatcgcaca cgtgatccgt gcggtgcaga cccggcggcc
     5881 cgcctcgtcg gtgatcacga cctcgtagct ggcggtgctc ccgcccaggt gcagggctgt
     5941 cgcgactccg gtgacggtgc ccgagcggac cggcaggtgg tgggtggcgt tgatgtccac
     6001 cccgacggcg atccggccct cccccgcgtg cagcgccgcg cccagcgagc ccagcgactc
     6061 ggccaggacg gcggaggcgc cgccgtgcag catccgctgc agctgggtgt tgccggtgac
     6121 cggcatggtc gccaccaccc gccggggggc cgcctccagg aaggtcaggc ccatccggcc
     6181 ggccagggtg tcggaaccgg cctcgttcac ccaggctgct gctgcctccg ggcccgcctc
     6241 gggggcgggc ggagcggcga aggtggtcat gccagggcct ccgtggagcc gtggtccgcc
     6301 gttgtcgtga cggccaccgc ctgcgggtcg gcggggcggt actcctccag cgctgcgtat
     6361 ctctcgcgca gttggcgttt cagtaccttg ccggtcgggc cgagcggaat cgcttcgggg
     6421 gtgggcgcta tctccagcag ggccagtcgc ggctgaccgg cccggtccag ggcggcgttg
     6481 gcccgccgca gcaggtcctc ggccgtggtc tcccggcgca gtgtcacgat cgccgccggg
     6541 acggtccggc cgcggtcccg ggccgcgacg acggagcagt ccgccagttc ctcgacggcg
     6601 agcaggagtt cctcctccat cagcgccgag tagccgtcgc ccgtctcggt ccggattcgg
     6661 tcgacagccc ggtccacgtg gaagaactcg ccgtcggccg agcggcgcac caggtcgccg
     6721 gagagccagt agccggcgag catcgtgcgg taggtggtgt cggagtcgtt ccagtagccg
     6781 tgcgcgagcg cctcgctgcg gactccgagc aggcccacct cgtcggccgc cgcctcggtg
     6841 ccgtcctcgc gcaggaccgc gacttcgccg atcgggaccc gggtgcccag gtgccgggcg
     6901 cgggacgggg tgtcggcggt gaggacgcgg cgcagggccg cccagcccag ctcggaggag
     6961 ccgagaccgt cgtcgatgat cgagcccggt gtgcgggtgc cgtcgggcgc ggtggtgtgc
     7021 ccgagccgca tcagccggcg catgtgcgcg tcgtggccgc agtcaccgag gttcacccac
     7081 accgcgacgg agtcgaagtc ggccggctcc ggctcgtgcg tggccaggtg cgagagcgcc
     7141 tcgttgaagg cgagcacgac gttcggccgg tgggtggcac agccgcgtgc gatgcccggt
     7201 ccggtcgggt cggaccagcc gatggtgggc accccggcca gcagcgagta gaaggtgaac
     7261 gcgatggcgc tggagtgcga ctgcggggct ccggcgagta cgagggtgcc ttcctgctcc
     7321 gggtggttga ccagccggaa gcgggccccg gcgacgctct gccggtgtgc ccagacgacc
     7381 ggtttggggt tgccggtggt gccggaggag tgacagatga cgacggggtc gtcgtccgtg
     7441 tgccggtaca gctgggaggg tttcggggcg cgggcgccga gggtgcccgc ctcctcgtcc
     7501 agggcggtcc agcgcagctc cggaagctcg cgctcccgcc cggcgagcag ggcgagccgt
     7561 tccccgtcgg tgaacagtcc cgccgatccg gtgcgccgga ccagcccgag ggcgagttcg
     7621 ggccgcatcc gcccgttgat caggaccccg atcgcaccga tgcgggcgag cgcggtcagg
     7681 tgcacctggt aggcgaaggt gtcctccagg tagaccgaca cccggtcgcg cggccccacg
     7741 ccccggtcga ggtaccaggc cgaccaggcg tccgccaggg cgtccagttc gcgcaggctg
     7801 aactcccgtc gaagggtgcc gtccggtccc gcgagcggcc ggtcggcgag caggaccggc
     7861 aggtcggccg cggggttcgt ctccgcggcg atccgccagg cgttgccgcc tccgagaccg
     7921 gggagctcgg cgagccggag acgtgcttcg ggggacagca gcggtgtgga cgtgagcggc
     7981 atcgattccc ctggtctcgg tcgggcgggc tttctggtgt cggcggcgcg accctccgcg
     8041 taacgcgtgc cggccaccgc ggcggacctg cgggaggggg cggtccgcgg cggcagcgcg
     8101 tgcagaaggt acaagcggct tctccgccag ggccaacgcg tgccgaaagt gcgtcaggtc
     8161 ggtgctgccg caggggtgtg gcgccggaaa tgccgtattt accgggcccc gagactccga
     8221 tgggcccggg gaagggccga aaggtgtctg tacgcggctg gatcggactt gacgaactca
     8281 gcgcggggtc gctgacgggc cgaggcacgc ccggctacgt tcctgccgaa ttccaccgga
     8341 gccgaccgca agccgcggct gccggacctc gtgcagcccg acaaggagcg cgtcgcgtgt
     8401 cgtctgaacg gatatccgat gccgtggagc gggtgcgcca catcgtggca tccgtcctcg
     8461 aactggacct cgtggaggtg acggccggag cttccttcca gcacgacctg aagatggatt
     8521 cgctggagaa ggtggagttc gcggcccggg tcgagtgggc cttcggtgtt gcgctgagcg
     8581 acgaggaggc tagcgggatc gacagcgctc gcgccgccgc cgtcctgctg gaatcccggc
     8641 tcccgcccgc ggcgggtgcc gggggcacgg ttcccggggc cggggtcacg gttccggagg
     8701 ccgcacggtc cgccggggtc cggaccgcgc cgtccccgcc cgtcgcggct cctgccgggc
     8761 cgtccgcgct gtcctcgccg cggcccgcgc cgcgctcacc gcgccctgcc gggcgccccg
     8821 aggctccgta cgcggggccc ggtgcctccg catcggccgt ccggccggga ggggcgcccg
     8881 tctccgccgg gatcgaccgg ggcgccggga tcgacctggt ggacagactc gtcggccggc
     8941 acctcgcggc gggccacggt ggccggaccg cctatctcga ccccggcctc ggcgcggtct
     9001 cctaccggga actgtacgag gcggcgcgtg gctacgccgg tgcgctgctc gcccacggtg
     9061 tcgcccccgg ggcccgtgcc ctggtcgtcg ccgaggactc cgtggccacc gtcgccgccg
     9121 tcctcggcct gtggtggcac ggctgtgtgc ccgtcccggt cagcccgatg ctcggcgagg
     9181 ccaatctcgc tcccgtcgcc gccgactgcg cggccgaggt cgtccacctc gacaccgaac
     9241 cggccgtccc tcccgcggcg gcggtgctgc tcacgggcga cgccgtacgc gccggcatcc
     9301 gtaccggcgg accgaacgcg gcgaaccgcc ccgacctcgc ccggccctcc accgggcacc
     9361 gtcccgggca gaccgccctg atccagtaca cctccggcag caccggccgc cccaagggcg
     9421 tccggcacgc gacctccgcg atcaccgcga tgctggacgg cttcggctgc ctgctcgccc
     9481 tgggcgccga cgacatcgtg ctctccaccg cccggatgtc cttcggctac ggcttcggca
     9541 gctccgtcct gtgcacgctc gacgccgggg ccaccgccgc actgatcggc ggcgccgtcg
     9601 acctccacag cgtccgggcc gcgctgcgcc gtcaccggcc caccgtgctc tgctccgtcc
     9661 cccgcctcta cgcggccctg ctcgacacgc tccgcccggg ggacgaggcg gtggccgcgc
     9721 tgcggttgtg cctgaccgcc ggtgagaact gcccggccga cctgaaccac cgtatccagg
     9781 acgtcttcgg cgccccggtc atgaactgcc tcggtgccac cgaggtcatg cacgtcgtcg
     9841 tcgccacccc gccggaccgg ccgatgcccg ggcgggccgg gctggcggtg cccggcacca
     9901 ccgccacggt ccgcgacggg cacggcaggc cggtgcccga cggcaccgag ggccgcctgc
     9961 acatcgcggg accgaccgtc gccctgggct acctcgaccg ccccgacgac gaccggacca
    10021 ccttcaccga cggcggcgcc tacacgggcg acctggtccg tcgcgcggcc gacggcaccc
    10081 tgacccatct gtgccgggcg gacgacatcc tcaacctcgg cggctacaag gtgccgcccg
    10141 cggagatcga ggcggtgctc cgtaccgtcc ccggtctccg cgactgcgcc gtggtcggcg
    10201 gtctcgacgc cgacgggctg gagtgtgccg tcgccttcgt ggtgccggac tcgtgggccg
    10261 acgaggaaac gattcgccgc accctccggg caacggtccg cgccgacctc gccctctaca
    10321 aacgcccggc ccgggtcgag ttcgtcgacg cactgccatc cacggccacc ggcaaggtgg
    10381 ccgcctacag attgcgtgaa caggcatcat gacgtgggac atcacaggga tgggggcggt
    10441 cgcctgcaac ggcaccaccc cgtcggaggt cttcgactcg ctctgcgcgg gccgcgacgg
    10501 ccgcgggccg ttgcaggtct tcgatcacga gaagtaccgc gcccggaacg cctacgagat
    10561 cagcgaccgc gccctcccgg gcgtcgacga accgggccgc gccacccgct ggctggtcga
    10621 cgcgatcgac caggccctcg ccgacgcggg ccacccgcgc gatctcaccg atgtgccggt
    10681 cctggtcggc accaccctcc aggagcagcg cagcgccgaa ctctggtggc gccacggctc
    10741 cgccctcgac cccgccgacc tgcacttcgg caccgcgctg cgggaggagt acggggcggc
    10801 ccgcacctac accttcgcca acgcctgcgc ggccagtctg tacgcgctgg ccatggccac
    10861 cgatctgatc gaactcggtg aggcggacac ggtcgtggtg gcgggaaccg acgcgatcgg
    10921 ggagagcgcc ttcgggaccc tggaccgggt ccagaacgac gtgcccgacg cgctgcgccc
    10981 cttcgaccgc tcgcaccgcg ggatgctgat gggcgagggc gccgtcgcgg tggtgctcac
    11041 ccgcgccgcc gcccccggcc gcccggtgca cgcccggctg cgcggtgtcg gcgtcaactg
    11101 cgacgcccag cactccaccg cccccgaccc cgaggggatc acccgcgtcc tgcgcgacgc
    11161 ctaccgtctc gccggggccg cacccgagga gatcgacctc gtcatgctgc acggcagcgg
    11221 caccccgaag aacgactcca ccgaggccac ggtgctctcg cggatcttcc cgcccggggg
    11281 cgggccgctc atgaccgcgg tcaagtcgat gaccggccac acgctcggcg gctccggtct
    11341 gctcagcctg acgacggcgg tgctcgccct ccagcggggg caggtgccgc ccgtgctcgg
    11401 cctcaccgac ccgatcgagg aggcggccgg tctgcggctg gtgcgggaac acgcggccgc
    11461 cgctccggag ctgacgctgg cccaggtcga cgcgttcggc ttcggcggga tcaacgccgc
    11521 cgcgatcctg gaggcagccc gatgagcaca gcgcaccccg ccgccccgtc ctcgccccgc
    11581 gtggcggtcg tcaccggggc gggactcgcc gttcccgggc tgaccctgcc cgacgaactc
    11641 ctcggcaccg tccgcgaggg cggcttcgac cccgccaccg gtctggtcgg gcgggacctg
    11701 cggcacaagg accgcgcctc ccggctcgcc ctgcgcgcca ccgcccccgc cctgcgggac
    11761 gccggtctgt tcgacggcga ccgctacacc ggccccggtg acagcaccgc cgtggtggtc
    11821 agcaccaacg tcggcatcct ggagaacgtc tgctccttcg cggacaccat cgcccgcgac
    11881 accgtcctcg gcctcagccc gctcgggctg ccgcagacct ccagcaacgt catcgccgga
    11941 tcggtcgcca tggcccacgg tctgcgcggc cccaacgtca ccctgtgcaa cggccccacc
    12001 agcggcctcg acgccctcta ctgggcccgt gcgctgatcg tcacggggcg ggccgacacc
    12061 gccgtcgtga tcggcgtgga gccggccggt gagatcgtga ccaagctgct cggcaccccg
    12121 gccctggacg gcgccgtcgc cctcgtcctg gagtcggccg accgcgccgc cgggcgcggc
    12181 gccgggatcc gcgccaccgt ggccggctgc gcccgggagg cggacctcgc ccgtgcggtc
    12241 gcccgcgccg gggggctgac ccccgacctg tggctgaccg aggcggcgga cgacccggcc
    12301 gggccgcccg cggactccgt cctggacccc gccgccgggc tcggcgccgc ctccggcgcg
    12361 ctcggcgtgc tccaggcggc cgccgccgtc gcccatctcg acgcgcacgg cgggcacacc
    12421 gtcctggcca cctgcggcgg gcccgagggc gacggcgtcg ccgcggtgtt cctgaccggc
    12481 cccgatcaca ccccctgaga atccgccccc gaagaagagg agtgccccat gaccgcccgc
    12541 accgaccagg cgttcgacgc cgaggagctg cgcaccgtcg tcgccgaggc gctggaactg
    12601 cccctggacg aggtcaccga cgacgcccgg ttcaaggagg acctggaggt ggactcgctg
    12661 atctcgctgg agatcgccgt ccgggtcgag gagcgctacg gcgtgaagat cgacgagtcg
    12721 cggctggccg agatcggcag cttccggctg gtacgggagc tgatcgaggc cgagctgaac
    12781 ggcgcgtccg ccacgtgagc gggaccggca ccacgggcgg ggaggcctcg gcgcgcccgg
    12841 tggccctggt caccggcggc tcgcgcggca tcgggcgggc cgtcgtcgcc cggctcgccg
    12901 aggacgggta cgacatcgcc ttctgctacc gctccgacgc ggaggccgcc gcggaggcgg
    12961 ccctgatcgc ggagaaggcc ggggcccggg tcctgcaccg gcccgtcgac gtgtccgacg
    13021 ccgagcaggt gagggggttc gtctccgcgg ccgaggagga actcgggccg ctgacggccg
    13081 tcgtcacctc ggccgggatc acgcgggacc gtccgctcgc cctgatggcc gaggacgagt
    13141 ggcgttcggt catggacacc aatctcgacg gcacgtacaa cgtctgccgg gccgccgtgt
    13201 acccgctgat gcgccgtcgg cgtggagccg tcgttacgct ctcctccatc gccggtgtgc
    13261 acggcagcgc gggccagacc aactacgcgg cgtccaaggc cgggatcatc ggcttcaccc
    13321 gctccctggc ccgggaatgc ggccgctacg gcatccgcgc caacgtggtc gcacccggtc
    13381 tgatctccac cgacatgacg gcctccctcc ccgccgacgt ggccgaacgg catctcaaga
    13441 gcattccgct cgcccgggcc ggcacgccgc aggaggtcgc cgacctggtc tccttcctgg
    13501 tctcggaccg cgccgcctac atcaccggcc aggtcgtcga gatcaacggc ggcctgccga
    13561 gctgaccgct gccgggcccg ggccaggccc ttcccgtccg tggcccgagg acggccgcac
    13621 ggcagcgggc gcgcgctccc ggcgtgccgg ccgcggaccc tcgtacgcga cgtacccggg
    13681 tccggggccg gtgcggcggg agcgcgggca gatcggcccc gctccgggaa ccaacccgta
    13741 cggccgccgc tgcgtctgac tccatgacgg acgaccggcc gatcatcagg gagagcacgt
    13801 ggcgcgcaag gacaggacga cggacacgac gggagagaag gattccgagc ggtggatggc
    13861 ccgtttccag gtgcggctgg ccatgcggcc cggcgtggac cgggcggtcg tgctccaggc
    13921 ggtcaaggag gtcacggcgc actgcgcgga gaccggggag catccgcaga cccgcttcgg
    13981 tgacccggac gcctacgccg tcgaggccgc cgcccggctg gtgccggcgg accggggggc
    14041 ccgtgcggag cggcacaacg gcgtgctgag gagcgtcgag tccgtcgtca ggaagatcag
    14101 ggacgtcccg ggtctgtgac cggccggagc gtacggggcc cggcacagct ccgtacgccg
    14161 ggccgcgcgg tggcacggac gaccggccga gcggctgggc cgggtggcag cgcccctgct
    14221 cgatccgtca gcccctgctg ctcgcgcgcc actcgagcgc ctgcggggtc tcgctgaact
    14281 ccaccaggtg ctctcccccg aagcgttcca gtgcggtgcg tacctcggcg ggggtgacgt
    14341 ggaagaactc cttcctgctg ttgacgcggt tgacgcggcg gtcggcgaac tcctggtgga
    14401 ggcgggtttc caggccgacg gcgtccttgc tgaagatcag ggcgtggacg tcgaagcgga
    14461 aggggacggc ggcgccgctg agttcgtaga cgcggtcgag gggttcgagg cggcgggtca
    14521 tgccgatctt gacgatgctg tcgccgaagg cgccgatgtt ggagacgacg tagacgtaac
    14581 cggtgcggac gttcgccgcc cgtgcgtcga cgtcctggag tgcctgctgg agctcggcga
    14641 gcttggcttc catgtcgcgt acggcgtcgt ggtcgccctg ggagcggagg cgttcgaggg
    14701 cggcctcgta gtggttgacc tccttgttca gtttctcccg ttcgcggtcg agttcgcgct
    14761 gggctgccgc ctcctcgcgt tcgcgggccc tggcctcgcg ctgggcttcc ttctcctcgt
    14821 ccttcttctg caggaagtcc gcggtcagcc gcagttcgcg gacgcgggcg tcgtggtagg
    14881 cgtcggagat gcggatgtgc atggtcgcgc cgagcctggc gatggtctcc cggctcttgt
    14941 agaggcggtc gaccagtgag gtgaggcggt gggggcgcat ggtgcgcacc gcgtagtcgg
    15001 cttccgcgtt gtaggcgcgg agcatcagct tggagaagtc gcggatcatc ctgcggccct
    15061 cgcgggcgga gccgttgacg gtccagtcgg tggcggcgag gaccgcccgg ttggtgcgcg
    15121 cgagatcctt gatctcggcc ttgagggagt ccaggcgcgt gcggtaggcg accgcgtcgt
    15181 ggagttggtg gtggtaggcg taaatgccgg cctgctgcag cagaacggtc tcgtcggtgg
    15241 tgacgagctg cgcgcgcagc tcggtcagac ggctttcggc ctgatagatc tcacggcggt
    15301 gccgttccgc ctccttgcgg gtcttctccg tgtccttggc gacctgcttg gcctcgctcc
    15361 tggtgtccct gacggactgg cgggcttcct cgacgatcgc ctcggcctgt tccccggcct
    15421 gcgtcagcag cacggccgct tcctggcgcg tgcggtacac cagtccggcg acctgggcgg
    15481 cgtccgcgcc gtgtgcccgg gcgatccagg ccctcagctc ttcgagctcg ctcgtcccgt
    15541 cgtgccgtcg gcggccgaac cagccccgct tccggccggc gggagcctcg ggcgcgggcg
    15601 cgtactggtg cgggacggca ccggtcgtcg gaggggcttc gggagggtcg gccagccaca
    15661 gctgccagcc cggcggaggc ggcggccacg acggatcggg ccgccagtcc tccgggggga
    15721 cccagccttc gggcaacagc cagttcggcg gtggattgaa ccggagaccg ctcacgccca
    15781 ctcgtacact cccccgcccg gccaccgttc ggtggcccgc cctcggcaac tcccgtgatc
    15841 atgccgcgca accttccgga aggggcgccg atcacggaga acggcgcaaa aggcaccctg
    15901 gcagctccgc tccggaggcg tacggcccgt cggcgggccc ctggtgttgc cgtggagtct
    15961 gccaacgttg cacgagcaga actggcaaca cggtgccgcc gggcgctcct gacctgggcg
    16021 tacggccgtg cgccgcttcg ccgccgcccg gcggttccgt tgccactact gcgatcacgt
    16081 aacgcaacgg ccgcgtcaca cctcatgctg tgtctcaccc cctggcggcc tgccgggcgg
    16141 ggatgtctcc cggccctgcg ggggtgggac ggatggagag ggggaggccg tggaacggcc
    16201 cttactgccg ctcagatcgg ccctggtgtt cctcatggcg gtgatcagcg gcataacggc
    16261 gggatgcctg tgctggatcg cgggggaagg cgtcgcgcgc ggtgtgctcg ccgggctcgc
    16321 cgtcgtcggg ctgtcggtcc ccttcttcga ccgcctgatc gcccctgagg ccgccgggga
    16381 cacccgcgag gaggttcagg accatgggtg agctgcgccc tctcggagag gacctgacgc
    16441 aggagtcgcg ggcgctcgcc caggcgctgc gggagctgtt cgaggggctg gacgtgtccg
    16501 tacgccgtta cgcggccagg caccgccgcg acccgggcac gttctcccgg tacctcaacg
    16561 gaacgcggct gcctccctgg gaggtgatca tgggcatcat gacggacctc gccgagcacc
    16621 gcggcacgac cgtcaccccg gaggccatcg agttcatccg cggcctccac ggctcggcct
    16681 tcgactccag ctcctccccc aagcacgcgg tggagatcat cgaacagcag ctggccgacg
    16741 ccgaccacgt ctcacgccgt tccagcgtcc gcggcgacat cctgggcgac gcgctcctgg
    16801 agcgccagaa ccgcatcgcc aacctggaag tgcgcctcag ccagatggag gcggccctca
    16861 ccgccgagcg tgagcgcgcc ggccagctgg cggcggccca ccccgacgtg tcggaactgc
    16921 ggggggagcg cgacgtgctg cggcaggagg tgacgcggct gggcgacgag ctccaggccg
    16981 cacacgagca gcgggacgcc gccgaggcgc gctgcgacct gctggagcgg cagctcgccg
    17041 ccgtcgagca cccggtcgcc ctgccggcgg cgccgccgct gcgtatgccc aaggtgctcg
    17101 tcgtggacga ccagcccgac aacctgctgg ccatggccgc cgtcctggag acgctggacc
    17161 aggagctggt caccgtctcc tccggccgcg acgccctcaa ggcgctgctc ctccacgacg
    17221 acttcgccgt catcatcatg gacgtgcaga tgccggagat ggacggctac gagaccgccg
    17281 cccacatcaa gcgcaggccg cgcaaccggg acgtgccgat catcttcctc accgcgatgg
    17341 gcgtcgaccc cgagcacacc gcccgcgggt acgcggcggg cgcggtcgac tacatcagca
    17401 agcccttcga cccctgggcc ctgcgcgcca aggtcgcggt cttcaccgag atccacctcg
    17461 aacgccggat cggcccgtcg gagggaaccg cctcccgacc gtcgtccgcg taggtccggg
    17521 tcaccgctcg gcgcggcgga tgtcgatgtt gccgtggcgg gtgcgggcgt ggaccttcac
    17581 cgtgtcctcg gcgtcctccg gggcctgcga ctcggtgagg gcgttgcgta cccggcccga
    17641 tcccgagctg acgtcgagcc aggcggcggt gcccttgcgg acgccgacct cgacggcccc
    17701 gtaggaggtc tccagccgga cctctccccg ggccacttcg gagacgagga gagtgccgtg
    17761 cgccgccgtg gccgtgaccg atccctcggc ccgggtgacg gcgatgtctc cgttggcacc
    17821 gcgcacccgc aggtcgtcca gcgcgacccc gacggtcgtg gtgccgtgcg agttcttgag
    17881 aacggccggg ccgtccacgt gcccgaggcg caggcttccg gagctggtgg tgatctcggc
    17941 cgggccctcg acccggtcca cggtgatcga gccgtgcgat gcggtcaggt gcagcgggcc
    18001 gaccgtgtcg agccggacgt ctccggacga ggtcttcaca cggacctcgc cgagccggcc
    18061 ctcgccgagc acctgggccc aggcgccggt catctcgacg cgcgagccgg cgggcagttc
    18121 gaccgtcacg tcgacggtgc cggtgcggcc gagcagtccg ggcctcgggg tcctgacggc
    18181 aagtgcgccg ctcgcgtacg tgacctcggt ccgcccggcc gtcgtcacgt cctggtcccg
    18241 cccggggtcg cggggccgta cgtcgacgac ggtacggggg ccgtcccccg cggtgaaccg
    18301 gatggagccg gcctccacgt gcgcggtgac ggagatcggt tcgggagtgt cgaaagaagg
    18361 catggctgtt ccgtcctcgt gggtcctggg gcgttcccgt cggcgggaac gtgctgtggg
    18421 tggggtggtg cagtggtacg ggaaggggcg cggtcagcgc acccagcccg tgaagctctg
    18481 tccggccgtc ggggccctcc ccgccgtacg cagccgggta ccgccgtcga cggcggccga
    18541 caccgcccgc accagccacg cgttgaccga caggccctcg gcggccgccg cgtcctcggc
    18601 gcgggccttg aggtgcgcag gcagccgcag gttgacccgg gcggtgccgc cctcgtcgcc
    18661 gtcggccgga atcctcgccg gttcggcggg cccggcaggc tgcaccggag ccccgtcccc
    18721 ggcctgcggc accgtcacca cgaagtcggg gtccagcccg cgcaggcgca cgtcgaccga
    18781 accgggggcg agttcacgcg tgacctcgtc catcgcggcg gagagcacgt ggagcatggt
    18841 cagccgggtc gcggactcca ggggagcggt gagccggtcc gccagggcgc gggcttcgtc
    18901 gccgcccgcc tcggcggcca ccgcgagctc acggcggagg gagtcgacat agggagtgag
    18961 atccatgacg ccatcatggc atcactttgg caccacatgc aagccatgac tacggacagc
    19021 agggggaatt cggcagagcg gaagaaggat aagggatttt tgaccgtttt gacggatacg
    19081 aggacgtact tccctctgct ttcgagtggc gccatatggc accgtggggc gccattgagc
    19141 gccaacccgc gccacgaaag tcgaaccctc gacggcggac acgggcgcgc gtactctccg
    19201 tccggcgggg cagccgaccc tcatgactgt tctgcgcaga gttgcccggc ccctgctggc
    19261 ctcgatgttc gtcagcggcg gattcaccgc ggtgcgcgat ccccagcgcc tggcgcccgc
    19321 cgccgcgccc gtggccgacg ccctctcccc ggccgtcgcg ccgcggacct ccctgctgcc
    19381 ggaggatccc gagcgtctcg tacgcctcaa cggcgccgta cagctgggcg ccggcctgct
    19441 cctcgcgctg gggcgggcgc ctcggctcgc ctcggcggcc ctggcggtga ccctcgtccc
    19501 gacgaccctg gcggcccacc ggtactggga gatcgaggat ccggaggagc ggtccgccca
    19561 gcggacccac ttcctcaaga acgcgtccct gctcggcgcg ctcctcatcg ccgccgccga
    19621 cacccacggc aagccctcgt tcgcgtaccg cacccgccac gccgccgctc acgcctccga
    19681 caccgtcgcc caccgggcgc accgggccgc cgacctcgtc ggcggcgcca ccgggggtgc
    19741 cgtggacagc gtcacgggtg ccgtcgaagc ggctcgcaag cgcctgccgt gagcccgggg
    19801 cgtcaccgcc gtcccatccg tcccggcggc ggcctccgcg ccgtcgccgg cacggcccgc
    19861 ccgtggggtc actcggtcac tttggcgatg aacgcggaca ggttcgccac ggtgcggcgg
    19921 accttctcct ccagggtgag cgactcgtgc agccgcgcgc cgatcccggc gtccttcttg
    19981 ccccgcacgt agagcgagca ggccagatcg ctgcacatgt aggcgccgac cgagttgccc
    20041 tgctggccgg ccttccctgc gcgcggggcc acgagcagcg agacgcctcc ggtgtgggtg
    20101 gtcacgcaca tcgagcacat actgcggcgc gtctgccagg agcccgcgtc cgaggaacgc
    20161 aactggagac cgaccgggcg actgccccag gccgccacga ggtaggcccg gtcgggggcc
    20221 tgcgggtcgc gccagcccag gaagtccagg tcggcccagg ggcgttcggc caggtcacgg
    20281 gggacgtgca ggcgcttggc ctcacccttg gtgcagttca cgaacgcggt acggatctct
    20341 tgctcggtca gcggtctcat aactgtcacg ctagtttgcc taatatggtt aggcaaatgt
    20401 atatttcctt aggcaatcgt ggggaagtat tcggatgggt ggtggcatgg cgaaggcagg
    20461 accggccgcg gaacgcgtgg tgagggcggg ggccgagctg gcggacgaga tcgggttcga
    20521 aggggtgacc ccctccgcac tcgcccggca gctgggcgtc aggaccgcga gcctgtactc
    20581 gcacgtcagg aacgcccacg acctcaagac gaagatcgcg ctgctcgccc tggaggagct
    20641 ggccgaccgg gcctccgccg ccctcgcggg ccgggccggc aaggacgccc tcagcgcctt
    20701 cgccgacgcc taccgcgact acgccttcca gcacccgggg cgcttcgcgg cagcccagtt
    20761 ccggctcgac gccgacgcgg ccgccgccag cgccggcgta cggcattccc ggatgatgcg
    20821 ggccatcctg cgcggctacg acctgacgga gcagcagcag acgcatgccg tacggctgct
    20881 ggggagcgtc ttcagcggtt acgtcggcct ggaggcggcc ggcggcttca gccacagcgc
    20941 ccccgcctcc caggagagct ggaccgagat cctcggcgca ctcgacgccc tgctgcgcaa
    21001 ctggccctcc gccacctgac cttccgccct cgacctctcc ggagcccggg cctccccgga
    21061 gcctcggctc ctcccgggcc ctggcctcag attcccggtg tcaggtcctg ccctgcggcc
    21121 ggacgaaccc tcgcgaggag aacgcgacga tgaacacccc gcacgagtgg atcaccaccc
    21181 ccatcggccc cgacatcctg cgcggcgccc tcgacctgga gcgcaccgac cgcggcgtgc
    21241 tgccccaccg gctgcccgcc cacgcccggg cccagatccc cgacgggcag ctggccatgg
    21301 ccgaggcgca gccctccggg gtccggctgg ccttccgcag ccgggccacc accgtcgagc
    21361 tggacgtgat cgccaccaaa cgcgtctacc ccggggcgcc gcgccgcccg gacggtgtgt
    21421 acgaactcct cgtcgacggc cggcacgtcg gccgggccag cgcgcccgac ggcgacaccc
    21481 tcaccatcga cctctcctcg ggcgcctcgc acgcccgccc ggggcccgtg gaaaccctcc
    21541 gcttcggcgg cctgcccgac gccgagaagg gcatcgagat ctggctgccg cacgacgaga
    21601 ccacccaact ggtcgccctg cgcaccgacg cccccgtcga cgtccagcgc tccggcggcc
    21661 ggccggtctg gctgcaccac ggcagttcca tcagccacgg ctccaacgcc gccaccccca
    21721 ccggcacctg gcccgccctg gccgccgccc acagcggagc ggaactgatc aacctggggt
    21781 tcagcggcag cgccctgctc gatcccttca ccgcccgcgc cctccgggac acccccgccg
    21841 atctcatcag catcaagatc ggcatcaacc tggtgaacac cgacctcatg cggctgcgcg
    21901 ccttcggccc ggccgtccac ggcttcctcg acaccgtccg cgagggccac cccaccacgc
    21961 ccctgctggt catctcaccg atccactgcc ccatccacga gcacaccccc ggccccagca
    22021 cctacgacct cggcgcgatg ggcgaaggac ggctgcggtt caccgccacc ggggatccgg
    22081 ccgagaccgc cgccgggaag ctgaccctca ccgtcatccg ggacgaactc gcccggctcg
    22141 tcgccggacg caccgccacc gacccccatc tccaccatct ggacggcctc gacctctacg
    22201 gcgagaacga tcacgccgac ctgccgctcc ccgacgacct ccaccccgac ccggccaccc
    22261 accgcctcat cgccgaacgc ttcgcccggc tcgccttcgg ccacgacggc cccttcgccg
    22321 gcacgggcca ctgacccctg aggccggggc ccgggccagg acctccaggc acggtcccca
    22381 cgggcgggcc ggagcccggc ccgccactcc cccgtcagcc gcggccccgc gcctcaccac
    22441 ccctccacga accggcgctc cgccggcagg agaccaccac caggaacggc cacagcgcct
    22501 ggacgaacgt caccacccgc tcggccacgc ccggcgcccc cgcgctctgc agctccgcca
    22561 gggaccacag cgccgtcgcc cccatcagcg cactcgcccc cagcgccacg tccggccgca
    22621 gcccccacgg caccggctcc ctcccccgga cggccgccag cggaggccac accgccagca
    22681 gtacgaggcc cagcgcggcc acggccccgt gctccagcgc cccgccgctg ctcggcgccg
    22741 gcaccaccgt caacgccagg gcgcacagtc cgccgccggc cagagccagc cgcccggccg
    22801 gggccgcctc ccacagtgcg tgtgccgtga ccacgtaaca ggtgcccagc accagcagca
    22861 tgcccgtcat cagccagtag ctggtggcac cgtaggccgc cagcacgctc agggtctcct
    22921 tcgcggggtc gtaccccggg ccctgccgct gctgcgcgat cgcccaggag ccgaccagca
    22981 ggaccggggc gcacccggag gagagcagag cccaccaagg agcagatcgc atcggagcag
    23041 cataaatcga tcaccccttc cttctgtcga tcccttggcg ggggtcggcg cgagccggta
    23101 cgaggaccaa ggcgcccggg ccgaccgttc gcgtggactc cgccccctca ccccgtaccg
    23161 gtcagtcggc ggacagagcc accgccccca ccgggcaggc ccgtacggcc tcccccacca
    23221 aggggtgggc tccggcggtc tccgcgcggc ccgggagcac ctcgctcagg ccgtcgtcgt
    23281 cctgcgtgaa cacgtccggc gcggtcagcg cgcacatgcc cgcccccacg cagcgttccc
    23341 ggtcgacctg gacgcccatg ccggtcacca ggccacgggc agttcgagca tgccctggat
    23401 cgtgtccccc ggtttgtggg ggatctcccg cgcgggtacg gcgagcctga ggcccggcag
    23461 ccgctcgaag agcgagcgca tcgcgatgtc gagttccgcg cgcgccaggt tctgccccag
    23521 gcactggtgc acgccgaagc cgaaggccag atggtgacgg gcgggccgtt cccagtcgag
    23581 cgtctcgggc cgggggaaca cgtcgtcgtc gcggttgatg agcgaggtcg agaagaggac
    23641 gccctcgccc ttgcggatcg tcaccccggc gtccggcacc tcgatgtccc cggtcgccag
    23701 acgctgcagg ccgtcggcga tggagaggaa ccgcaacagc tcctcgaccg ccccggccgt
    23761 cgtcgtcccg ccggcccgca gcgccgcgag ctgctcgggg tggcgcagca gggtgaaggt
    23821 gccgagcgag atcatgttcg ccgtcgtctc gtgccccgcg atgagcagga tcacggcgaa
    23881 cgagaccagc tcctcgcggt cgaccggtcc gccggggtgg tcgcggtgga tcagttcgtc
    23941 gaggaggccg tcccccggtt ccgtacgttt gcggtcgatc agcgcgccga ggtactcctc
    24001 gagttcgtcg agggcccggt cgacgtcgtc cgcgccggga ccgcgcagga gccgccgcga
    24061 gcgctcctcg aagaactcgt ggtcggcgta cggcactccg agcagggcgc agatcaccat
    24121 cgacggcacc ggcagggcga acgcgctcac cagctcggcc ggtggcccct ggcgttccat
    24181 cgcgtcgagc aggcggtcga cggtctcctg gatgcggggg cgcagggcgt tgatccgctt
    24241 cacggagaag gccgggatga gcattctgcg ctgcgtgttg tgctcggggt cgtcgacgcc
    24301 gagcagggcc acgcggcgcc ggttcgcgtt ggcgaagcgc ggggccgggg cggggaagtc
    24361 cgggtgggtg cggtcggtgg agagccgtgg atcggccagc agccgacgcg ccagggcgtg
    24421 cccggtgacc gcccagaccg ggcgcccgtc gaagagggcc accctggcga gcgggcggcc
    24481 ctcacgcagc ggcgcgtacc cggcgggcgg gtggtacggg cacccccggt cctgcgggaa
    24541 gggtgtcgcg ggggccgggt cgacggcagc cgcggtggcg ggtgcggcgg agccgggggt
    24601 ccggcgggtc gtcgggtctg tggtggattc cgtcatgggg tggggtcgcc tcgcagtgct
    24661 cggtcgtgtg cgcggagccg atcgttccgc gcctcgacac cattggatgc cttaggcacc
    24721 tatgtggtcg acaggtagac cggccagctc aacagggccg tcggactggc cggtgtcttt
    24781 cgcacacgtt cgaaccgcgt cgcatccgct cagctccggg ggtacggatg ctccgccgtc
    24841 gagccgcaga ccgggtcgcc cacggcctga accgtgcgcg gacacggggc cggaatcatg
    24901 ccgttccggc cgctgccacg cgctcccgtg gtccggcgtg gcagcggccc ggcgaggggg
    24961 cgcgccgtgg ggccggccgt tccgcgcggg gttgcgtgcg cggtccgcag cgactccccg
    25021 cccgcctcgg cgctcccccc gggcccgtgc ttggataccg cccatggacg acctcacccg
    25081 tatgtggatc agcaccgtcc cggccctcga cccggagagc cgggaggtga tcctcggcct
    25141 cgaccaggcg tcggccgatc cggccgagcg catggtccgc ctgctgctca accgggggca
    25201 cgagggggag gacggggtct tctacctgct gcccgacgat ctggccgcgt ggtacgagcg
    25261 cagcggcgac cggctcgccg tcaccgtctc ggcacaccgg gacgtcctcg cccacgatct
    25321 cgccgcgtac ggcgaggagt tgcgcgacgc cctggacggc cttccccgcc tcgcctccga
    25381 cggtggcgag cacgtcgtgc ttctgcgccg ggagatcggc accgacttcg tgcccgccga
    25441 gcaggacggt gagccgcagc ccgtcctgct cctcgaccac gtcggcgggc cggccggtcc
    25501 ggccgatccg gcccgcctgt tcgagagcgg cgaggcgagc atcgcggtcg tcaacgccgc
    25561 ctggagcccc gagggggccg cacagcacac gccttcctga agccgctcct ccccggcgac
    25621 ggcgcctcgt ggtcgtccgt tccgccgcgt tgcggcgggg gcgtgggcgg cacgtaccgt
    25681 acgcaggtga acgaactgcc cgacgccatg accggaccca ccgtggacga gcgtgaacag
    25741 gccgccacga tccgcgtgtt cctggcgctc gccccgcccg acgatgccaa ggacgagctg
    25801 gagcgggccc tgggtcccgc ctatgcggcc cacccccgcc tgcggtggaa ccggatcgag
    25861 gactggcaca tcaccctggc gttcctcggt gaactcccgc cgtcctccgt cccgcccctg
    25921 atgtccccgc tctccgggct ggcggcaggg cgccggcccc tgcggctggc gctgcgcggc
    25981 ggtgggcact tcgacgagcg ggtgctgtgg agcgggatcg acggggacct cgaagggctg
    26041 caccggctcg ccaccgacgt acgtgggctg gtccgggcct gcggtgtctc cttctccgag
    26101 cggccgctgc gccctcatct gacgctggcc cgctcccgcc ggggcgaccg gggcgcggcg
    26161 gtggagatcg ccgcgggact cgccgcgttc tcgggccgga cctgggcggc cgagcggctg
    26221 catctggtgg gcagcaacat cggccggggc ccggggccga tccactatcg agacatcgag
    26281 gcctggcgtt tcggccacgc ggcctgacga tcggtgcccg gccggcgatc tacagcgccc
    26341 cctggctctt tgccgcgcat gccgccatcg acagcgcgct cagggaactc aaggaggccg
    26401 acgggcggtt gccggagttc acgcccggcg cctcgatcgg gtgcgggcct cgaccgcgcg
    26461 gctggagcgg aacatcggcc gccgccaccc gcccggcacc gggccgcccc cgccgtccgg
    26521 gggggggagg cctcagcgcc ggtgcgacac cgccagctcg atgaggtacc gcttggtgac
    26581 cgtgccgccg taacccccct cgatcagcgc ttcgacgcat ccgagcagcc cgttcctggc
    26641 agtgtccgga agggcgcggt ggccggagaa ggtccgcagc aggtccagat agccggaggt
    26701 ggtgaaggtg atgtcctgct cgtagcggcg caggaccgtg gggccgaacc ggccgctggc
    26761 cgcgacctcc cgcgcatggt ccgatccgtc gacgtcggcc gccgccggag gtctcagccc
    26821 gggcggggtc cgtgggtcga agcgctcgta gcagcgctgg acctcgacga agaactcctc
    26881 ggtgccgccc cgcacatgct ggccgcgcac cacggcgagc gccccgcccg gacgcagggc
    26941 gtcggcggcc ctggtcagcc gtaccgccgg gtcgatccag tggaaggccg tcgccgagac
    27001 cagcacgtcg tacggttcgc ccggcagcgg ccagtcctcg aagcgggccg tcaccacctc
    27061 cgcctccgcc gggccgaaac cggccccggc caggttgcgg cgggcgagcg cggccatgcg
    27121 ggggcccgcg tcgacggcgg tgacacggca gccccgtgcg gccaggggca cggtcgcctg
    27181 gccggtcccg cagcccacct ccaggacgcg gctgccgggc ccggcaccgg ccagccgccc
    27241 gagatcctcg tacagccgcg gcggatatcc gggcctggcc cggtcgtaca gctccgcgtc
    27301 ctcgtcgaag gtgcgggcca ggcgctcccg ccgcggctcc tcgggcaggt cgtcgcgccg
    27361 gggcggcggg ccgccggtca tgcggtgtcc tgccgtgcgg gacgggcgtg ggtcaggagg
    27421 aattcggtcg ctcgcgcgat ggcctcggcc gaggtgccgt aggcggcctc ggactcctcc
    27481 tcctgccggt ccgccgcggt ggccgtgtac caccaggcat ccgcgcccgg gtcgtggtgg
    27541 atgacggcgg caccgcccgc gtagtccagc gggatggact cgtcggccgg cctcttcacc
    27601 acggcgtggg gccacttgag gcgggcggac tggcgtctga tgccgcccca ggcggcgccc
    27661 agctgggtgt agctcgcccc gccccgcccg gccgcggtgg ccgcgctctc ggccagccgg
    27721 tcgaccgaga gcctggcctc gtacagcgaa cgcagcagcg ccagctgcag gtcgggggcg
    27781 gccatgagcg cggcgtcgaa gggctgcccg gcggtgcggt aggcatgggc acgtgtcgat
    27841 atccgctcgg ccagggcgcg ggccgcgtcg agcaccttcc cgtccatctc gaacgtgtcg
    27901 tcgtcgccgg gctcactcca ggcgggctcc accggcgcca tgaccacgga ccagaagttc
    27961 tcgtcgtggc gggccggggt ggggatgacc gtcgcctcgt ccatgcgaca agtctagctg
    28021 tcattcgcgg gagacgacaa gggaagctgt cactctttcg ggggttcgtc cgggatgtcg
    28081 accgcctcgc ccagggcgac cgtgaggcgg ccgagcgtct cctggagcgc gagcacctcc
    28141 tccaccgaca gaccggtcgc cgcgagcacg ccccggggga tcgacagcgc gctctcgcgc
    28201 agccgcacac cgtcgcccgt cagctcgacg accacggaac gctcgtcctc gcggctgcgc
    28261 tcgcgccgga ccagccccgc cgcctccagc cgcttcagca ggggcgacag ggtcccggaa
    28321 tccaggtgga ggcgctcgcc gatcgccttg acgggccggg ggccgtcctc ccacaggacc
    28381 agcatgacca ggtactgggg gtaggtgagg ccgaggccct tgagcgcctg ccggtagaag
    28441 ccgccgaacg cgcgcgacgc ggcgtgcagc gagaagcaga cctggtggtc cagtcgcagc
    28501 agctccgcgt cgggcacgtc ggcgaggtcg ggcgcggggg tggaggcggg agggggagcg
    28561 gatgccggct tcatgggtcc agcgtaccgc cgaccgcgcc attgagttgt gcacaactta
    28621 atggtgtgca actattactt ccgtgatcgc ggacgatccg ttcgcggtac cgacgaagga
    28681 gggtcatccc atggacgcgc tgtacaccgc cgccgccacc gccaacggcc gcgaaggccg
    28741 ggccgtcagc tccgacggtc agctcgatct gccgctcgcc ctgcccccgg ccctcggcgg
    28801 caacggcaag ggcaccaacc ccgagcagct cttcgcggcc gggtacgcgg cctgtttcgc
    28861 cagtgcgatg gcggcggtcg cccgggagat gaaggtcgac accaaggacg tctccgtgac
    28921 ctcggaggtc tccatcggca aggacggcga cggcttcggt ctctcggtcg tgatgcgcgt
    28981 ggagctgccg gactccctca ccggtgaggt cgggcagcgg ctggtcgagg ccacccacgc
    29041 ctactgcccc tactccaagg ccacccgggg caacatcgac gtcgagctgg tcatcgagta
    29101 gtcggaccgc cgcgctccag gcgctccagt accgccgtga ccgcgcggtg cacggcctcg
    29161 cgggacgcgg ccgtccggtc gagcgtctcg aagccgtggc ggcccgccgg tacgtcgacc
    29221 acctcgacgt cggccccgcc acgtgcggcc gcggtcagga actcctcgac ggtcgcggcg
    29281 atctcgggca tctcgcgccc ggcccggacc agcacgatcg ggagcctccc cgcccgggcc
    29341 accgcccgta ccggccggaa ccgggcgtcg gtcactcccc agctcggcag cggggcgaga
    29401 accgggtagt tgagggccag gcagcgcagc cagggtgggg gcgccgccag ccagtcggcg
    29461 gtgagcgggc cgccgccgga gaagaaccac agggcgaccc ggtcgccgtc cacccggggg
    29521 tcggcccgca cccgttccac cgcgtcggcc acgtcctccg cggcccgccc gtagtcggtc
    29581 acggcgtgca ggcggtgatc gagcacggcg ctcgcggccc cgcgcccggc gacgtaccgc
    29641 gcgtaccccg tcagggtcgg ccagtcccgg ggcgtcggcc gggcgtcgac gggtacgggg
    29701 ccgccgtgga cgaacaccac ggccggatgc ggtcccggcc cttcgggcag gtacaggtcg
    29761 gtgttcccgg tccgttcgcg gggccgctcg gggacgtcga ggaggaacgg ccgcaggtgc
    29821 gggggcgggc caccggtgcc gggggcagtc agccggtggc ctccgcccgc ggccgcctcg
    29881 gtcaggacac cggccagctc ggcggggcgg gagagcatcg gccagtggcc cgtggggagt
    29941 tcgaagaagg tcacccgggg gccggccagg gcctggaggg cgggttcgcc catgtccacc
    30001 atcagctgga ccagttcgat gcccggcccg ttgcccgtgc acagcacccc ggtcaccggc
    30061 acctccgcca ccgcgccggt cagccgcagc ggctgcagca gggtgcccag cggctgcggg
    30121 gcggcgaggg cggtcagccc gtccagcgcc gcttcggaga gccctgccgt actcccccac
    30181 cgggaccagc cgtcccgcgc gggcggcggc agttcaccgc cggtccgccc tcccccgccc
    30241 tcggcgagtt cctcgcgcag gcgctgatcg gggacggccg ccagggcggg gacaccgtcc
    30301 cccggcatcc ccgagtccag gtggacgatc cgggcgaccg ccaccacccg ccggtcggcc
    30361 gcgcccagca ccgggtggat gccgtagtca tggccgacca gcacgatgtc accgccgccc
    30421 cgggccacca cctcgtcgat caccgcgagg acgtccgcga tatgggtctc caggtcgacg
    30481 gactccgccg gaccacccgc tcccttgccg agtccggtga gcgccaccgt acggacgtcc
    30541 gcgcctcccg ccgccaggta tgcggccgtg tcccgccata cgtacggtcc ggtgaacgca
    30601 ccggccacca ggatgaatac ggtcatggtt cctcctcgtc acgctcttcc gtgcgcgccc
    30661 cggcccggct gttccggcag cgctcgccgg taccgtagga actcctcttg ggggaggttc
    30721 aagtgttctc gtcgcacgac ggtctctgca cgatcggtga gctggccggg cacgcggggg
    30781 tcagcgtcaa gaccgtccgc ttctactcgg acggcgggct gctgccggag gcgtcccgca
    30841 gtgcgggcgg gcaccgcaga tacgggccgg aggccgtgga gcggctggtc ctgatccggt
    30901 cgctgcgggg gctcggcctg ccggtggccg aggtgcgccg gatcctcgac gagcaggacg
    30961 ccgggggtac gggggacgcg ctggagagtg ccgtcgccgg gcgactgcgg acactcggcc
    31021 cggagctgag ggcgctgcgc tggcgtgagg cggcgctccg gctcgtacgg gactgtccgc
    31081 cggccgaacg cgccgcccgg ctgcggctgg tcggggcggt ggccgaggcg ccgagcaccg
    31141 ccccgctggt ccggttctgg cgtgcctggc tgcccgcgcg gatgcccgcc cggtccgtcg
    31201 gggcgttcct ggaggtggcc gtaccgcagc cgccggagga cccccggccc gcgcaggtgc
    31261 tcgccttcgc ccggctcaac gcgttcgtgt ccgggccgtg cgacgggagg ggcgggccct
    31321 gtcagcccgg cgcgcacgag gcggcggggg cgcgcgagtc ggcggtgctg tacgcggggc
    31381 tcgccacggc gtacgacctg gcgggcgagg agctgcggcg gggtggagta ccccgttccg
    31441 gggaggcgct ggacggcttc gtggacgcgt acgcgcgtac gtacggcatc cgcgacactc
    31501 cgtcgttccg ccgccggctc gtcgggcagc tcgcgggcga tccgc
//
