LOCUS       NZ_KB890923            31543 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces sp. CcalMP-8W B053DRAFT_scaffold_16.17, whole genome
            shotgun sequence.
ACCESSION   NZ_KB890923
VERSION     NZ_KB890923.1
KEYWORDS    WGS; GSC:MIGS:2.1; IMPROVED_HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. CcalMP-8W
  ORGANISM  Streptomyces sp. CcalMP-8W
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 168733)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
REFERENCE   2  (bases 1 to 168733)
  AUTHORS   Currie,C., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. CcalMP-8W
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            num_replicons                     :: Missing
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            assembly :: Velvet v. 1.1.04; ALLPATHS v. r41043
            finishing_strategy                :: Missing
            environment                       :: Missing
            trophic_level                     :: Missing
            sequencing_meth                   :: WGS
            Funding Program                   :: DOE-GLBRC 2011
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: Improved High-Quality Draft
            Assembly Method :: Velvet v. 1.1.04; ALLPATHS v. r41043
            Genome Coverage                   :: Unknown
            Sequencing Technology             :: Unknown
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 03:14:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,603
            CDSs (total)                      :: 6,529
            Genes (coding)                    :: 6,424
            CDSs (with protein)               :: 6,424
            Genes (RNA)                       :: 74
            rRNAs                             :: 6, 1 (5S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 35 of 105
            Pseudo Genes (incomplete)         :: 83 of 105
            Pseudo Genes (internal stop)      :: 5 of 105
            Pseudo Genes (multiple problems)  :: 18 of 105
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:04:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 125888
            Orig. end                         :: 157431
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KB890923.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405361
            Source DNA and Organism available from Cameron  Currie
            (currie@bact.wisc.edu)
            Source DNA available from Cameron  Currie (currie@bact.wisc.edu)
            Organism available from Cameron  Currie (currie@bact.wisc.edu)
            Contacts: Cameron  Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31543
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="(micKC and not PKS_KS)"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..31543
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-iii"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22691
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22691
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12691](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12691
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(133..147)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            complement(223..831)
                     /locus_tag="B053_RS0112310"
     CDS             complement(223..831)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511303.1"
                     /locus_tag="B053_RS0112310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GAF domain-containing protein"
                     /protein_id="WP_026237680.1"
                     /transl_table=11
                     /translation="MTPKSDSALSPAPVPAASPSDAHRDELLQSVVDVARAIFGAAAGS
                     VLLLDEEADELVFRAVSGEGQEFLVGRRFPAGRGIAGWVATSGEPMVVDDLTDDPSFDR
                     SLAESTEYVPDSLMAAPLISDSRVLGVLEVLDASPQARSSVRELDLLAMFARQAAAALR
                     VITPEPAAAAPAARPLEAAEREDALRLLGSLEQVLRGTA"
     gene            complement(815..1639)
                     /locus_tag="B053_RS0112315"
     CDS             complement(815..1639)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380876.1"
                     /locus_tag="B053_RS0112315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_018488903.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.9e-24, bitscore:
                     78.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGDPGPPGGQPAAPATGRGVRVCVVDSGVERDHPLVGEPASSWV
                     VVKDGESGEITVEPTTTGDTCGHGTACAGIIRRTAPECEIHSVRVLGERFSGTGDILMA
                     GLRWAVEQRFDVVNLSLSTTRTRFAQELHSLADSAYFARTVIVASAHNTPVESFPWRFA
                     SVISVGSHQEDDPDLHLYNPAPPVEFFGPGQNVTVPWLGGRTIRTTGNSFATPYVAGLC
                     ARLLSAHPRMTAFQLKNALYLSAANVRHDPSTADHAPRPSTAAGDTHDDAEI"
     gene            complement(1788..5330)
                     /locus_tag="B053_RS01000000133870"
     CDS             complement(1788..5330)
                     /GO_process="GO:0009190 - cyclic nucleotide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0035556 - intracellular signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380877.1"
                     /locus_tag="B053_RS01000000133870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="WP_078507673.1"
                     /transl_table=11
                     /translation="MICPSCRQDLPATARFCSSCGTPCAGPAAAAPPAPVAPPPEDERK
                     PVTVLFCDLVGSTALSGVLDPETLRTVTLRYFEAMSAQIVARGGTPEKFIGDAVMAVFG
                     VPVVREDDARRALAAALGMRRALDALNEELDASLGIRLTTRVGVNTGQVVAGSDATARQ
                     ALVSGEVVNIAARLEQNAGPGEILIGPQTLLAAGPTVKAVPTGPLRLKGKRESVEAYRL
                     LALGADDPELLRRFDAPFVGRAAELTTLDQALEKTVRNGHPGLLRVTGEAGIGKTRLVR
                     EWLTHHGGEGAFRHGAGRCRTYGDHGTLTPLADAVRSLLSQTDAPADPADPHGDAHPHR
                     DAHPHRDADAPAGTHPHTDANPRTGTPQDADTPDDEATADAMALLSGGLLRDGTPNAPF
                     EDMCAALTAVLKRAARTRPAVLVLDDWHAAAPLLVRTVERLAGDTGPARTLVICAGRPD
                     GMPEGRAHLHLSGLPREEAARLAAGLARLDGKSAPADERLLARAEGNPLYLEQLLVGEQ
                     LPDGGPGAATTPSDPDRELPPTLQALLGARIGALARPERGVVDLAAVIGREFAAAELVR
                     LEQTVRTEQSARTPDRARAAADGPGVTAAGPGAAADGGDGPATTPQDRHRVDEALAELA
                     RRRLVEPARPSGAGDPSAYRFSSGLVHEVAYSSLSKRAKAERHAWAADLPSVARTGDGA
                     VGGHLERAYRYRAELGLLDDRAQELRDRAAAALGRAGAQAAARSDLHWAHGLLERAVEL
                     RPDAARAVLGLGEVRVALGRTEEGAELLRNVRDLTTAPVESAHARLALAVLDPTAPPGP
                     AATARAVLPVFEAAGDAVGRARAHLRLAQRLQQSGRHEEAERDHARALEHAVAAGAEPE
                     RAGALGAIGISLWRGPVPVPEAVERCRALLTAHGAGRPTVRVTLNCPLAVLYGLQERSD
                     EAYACLAEAERLAGKLGFAEAEVFLPVFRATVEAVLGRGAQALELLARADAAARRVGAA
                     GMRTAVALDAARLELDAGAEGRAVEWLATVAEPSGLSGADAVDLEGLRARLAAREHPDE
                     ALHHADRAVRASLLTDSPLVQATAELDRARTLATLGLTAAAEAAARSAADHFTGKGHLP
                     GARRATAFRTALHRPRTRTTTDTATTDTATAGTVAADTATADRGTTGTGTADTAGVDLT
                     TADLATTITVREGS"
     gene            complement(5704..5886)
                     /locus_tag="B053_RS0112325"
     CDS             complement(5704..5886)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450780.1"
                     /locus_tag="B053_RS0112325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aroma-sacti cluster domain-containing protein"
                     /protein_id="WP_018488905.1"
                     /transl_table=11
                     /translation="MEETLHAAGFPVDLLTDEQRLVLGELTTQELTLLLDVKSRLDAVG
                     PEVQAHGEIAGGALF"
     gene            complement(6024..6737)
                     /locus_tag="B053_RS0112330"
     CDS             complement(6024..6737)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766799.1"
                     /locus_tag="B053_RS0112330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="WP_032779929.1"
                     /transl_table=11
                     /translation="MDVSARLRTKLLLLEPEFRGATSHMWRPEGLLERYRTYLCTMHAV
                     IRASVPLMELALRRMADRPGDPLSGPLTAYLAEHIQEEAEHDAWLLEDLRAAGAAPEDA
                     LGPLPPPDVAALVGPQYYWIEHHHPVALLGYIAVLEGYAPAPGLTDRIGGLTGLPAAAL
                     RTVREHAALDTGHLDELYALLDRLPLTRGQEAAVAVSALHSFDALTRLFVRLGRSAPAP
                     SLRGAGPTPPTGVTR"
     gene            complement(6749..7894)
                     /locus_tag="B053_RS0112335"
     CDS             complement(6749..7894)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046103.1"
                     /locus_tag="B053_RS0112335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_018488907.1"
                     /sec_met_domain="PF04055 (E-value: 1.5e-13, bitscore: 44.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELAELVGLRPFPAAGLLLGLTRRCPLRCRHCSTGSDLTVREEPN
                     AAQLLRFVGSFTTENRPDVVMLTGGEPLLLPTLAGELSFLARRAGSRTAVLSGMFFARS
                     RRIPPAILRAIAQVDHFSASLDVYHEREVARAEVFRALHHIRESGVSVSFHLTGTGADD
                     PYLADITRAIDKEFGGRVPSLVNEVRPFGRAASWARPARTGPDPSAAAPCSMAAWPAVA
                     FDGTVLACCNQDTVDRRPAPAHLDLGHIGSDDWAAVRRRALESPVLRMIRTVGPTHLAA
                     RSGAAPQPGSYCDGCRALGGNEAVAAGARAVASGPAGALLDLAAARRGALGGPEGVVRR
                     HGCSAYARLVGAGAEAAADAAGTGSEAGAGTGVRTGAGSMR"
     misc_feature    complement(8019..8033)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.07"
                     /tool="antismash"
     gene            8201..8362
                     /locus_tag="B053_RS1000000137140"
     CDS             8201..8362
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766395.1"
                     /locus_tag="B053_RS1000000137140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018488908.1"
                     /transl_table=11
                     /translation="MSENTKPAADENNETETPEVEAHSVLDLQETPGVIDREIVPGNCV
                     STVSLVLS"
     CDS_motif       8201..8326
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSENTKPAADENNETETPEVEAHSVLDLQETPGVIDREIVPG"
                     /locus_tag="B053_RS1000000137140_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8327..8362
                     /prepeptide="core"
                     /locus_tag="B053_RS1000000137140_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="1049.2"
                     /monoisotopic_mass="1048.6"
                     /core_sequence="NCVSTVSLVLS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSENTKPAADENNETETPEVEAHSVLDLQETPGVIDREIVP
                     G"
                     /leader_location="[8200:8326](+)"
                     /alternative_weights="1067.2"
                     /alternative_weights="1085.3"
                     /alternative_weights="1103.3"
     cand_cluster    8427..31543
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    8427..31543
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[18426:21543](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(18427..21543)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
     gene            8667..9989
                     /locus_tag="B053_RS0112345"
     CDS             8667..9989
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056551.1"
                     /locus_tag="B053_RS0112345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_018488909.1"
                     /transl_table=11
                     /translation="MATPLRSNRDFRLLWLSGLFAVLGSQMSALALPLLVLKMTGSAVQ
                     AGAVGTVSVCALLVTMLPGGVMADRVERRRLMRLCDAGSLAAVTALTIAVWYGHAPMVL
                     VLLVATSGAVLSSVYGPAAFGLMRAVVPPDQMGTATARLQARTSTVKMVGPLVGGGLFG
                     IHEALPFAAQFLGLLLSTVCVALVRTRSEARSRAGSVFSRRELTAGLAFLWQLPYLRTV
                     LLVFGLGMNFAFGALTFTALAVFSDNGASGLGGGFVLTCVSAGSLAGALIAPRIAPDRH
                     ARALIVATCWACVLTAAALAWLSSALLAGLLCAICMCLSTVASIGFLSTLLIVTPEDRI
                     GRVQSAAGFLSSMVQPFGPLAGGALLTLLGSRIAFGTIGCVLAVSAAVVTLAPSVRAGA
                     AAIPSPTEPEGLPGLKPDPKPEPEPAGTSRPAPDPAGPGAH"
     gene            10001..12691
                     /gene="lanKC"
                     /locus_tag="B053_RS0112350"
     CDS             10001..12691
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046100.1"
                     /locus_tag="B053_RS0112350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_018488910.1"
                     /sec_met_domain="micKC (E-value: 3e-211, bitscore: 696.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3e-10, bitscore: 32.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVSGIQQTQLYCLADPTYYETPARLRDEETRYPLDSAPPPEGRR
                     RVRNGLWTSLLPEDREIAEQGWKIHISTVPEEAEATLRDTARICLAHGVPFKFLRSEQA
                     LLLMSDKYMARSGAGKFLTLYPPDETVFLRVLDELVPALTGRRGPYILSDLRIGDAPVY
                     VRYGAFVARWCLDADGERVPALRHPSGELVPDERGVVFRVPPWVTVPEPLRPHLAARAA
                     AGDTTFPYTVTESLQFSNAGGIYRARHRETGRQVVLREARPHSGLDAVGHDAVTRLHRE
                     YRALTALAGLDCVPEVHGVRSVWEHHFLIEEHIEGSTLLEEIVARFALLHGAGTDAELA
                     TYTAWVDSVAERLAQALAAIHARGFRFGDLHPTNVIIRPDGRLVLVDFEYATDLDDQDT
                     PVAGAPGLQAPTGTPGAESDAYALWATWLYMLMPIMEMAGHDRAKAVTLERWARRRYRL
                     AADAGPIRPAALRAAEDRLGGEGEIAALLDGPVPDWAELRTRLIAGIHAGATPERTDRL
                     FPGDPQAFATGGGDLAHGAAGVLYALHRVGAPVDPAWTDWLSDAARRRDPAAPGGLYGG
                     LPGTAVVLSLLGRADEGRELFERAAAAPPSASADLLNGRAGIALAALRLARPGGAGSGR
                     PAAAAGPVTAADPDAKVDHDLVELALRTAHDLDRLVRGESVPGLAAPASAGLLRGLSGA
                     ALLHLELHALTGDDRHLRAAGRALEREAGHCVAMPGGTVQVKDGRRHLLYLDQGSGGVA
                     LVAQAYLAHRAAPSLAALLPGVRRGCTLEFIREPGLFTGRAGLMATAGQLSPEGRRAPD
                     VLASVRNLSWHLLAEEDRLLVPGARLRRCSADLATGAAGLLLALHFLSGGGTGTGGAGT
                     GATGAGAAGTGTDGTPGLLELLTLG"
     gene            complement(13028..14929)
                     /locus_tag="B053_RS0112355"
     CDS             complement(13028..14929)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019765558.1"
                     /locus_tag="B053_RS0112355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_018488911.1"
                     /transl_table=11
                     /translation="MIRPPARPVPAGAVYFSLLGPLTAVRDGRPLPLGPRKQRIVLATL
                     LARPNTPVSVDVLTDAVWPEDPPRTARKNLQVYVSAARTLLGSTGDEDRERVVHGCGGY
                     RLTIGEGELDTLRFRSLARAGRTAGERGDLRAAARLLREALDLWEGPPLNDLRDSTGVA
                     EEAERLEARCLTVYEDWAEIETELGRGAAAVDGLRDLVDRHPLRERLRVAWMNSLHQSG
                     RQAEALAVYDDYRQLLARELGLEPSPAMAALYKVMLGRGRTHRPPTGGRESARGTALPA
                     APRHFTGRREELRELLGLLGAADERVAVVSGPAGSGKSALALRAAHLLGDSFPDGRFHV
                     GVRREDGSARTPAEVLDELARLCGVRVPGSVPGVTGGSGGVPGGAAGVVPAVGVAVAVS
                     QGAEDAWQEWLSLHRALIVLDDVPDEASVRGLLPRSSGPSSVVLTARGQLPGLAPVHRI
                     ALAALADAEALELLGKLIGPGRLRTDPAAALRIVRACGALPLAVWVSGMRLAVLRHLPL
                     AEFADRLGDPSAALDELVAGDVSVRRRMASGWQDLAADDRRALGRLAGPAQEGGITLDG
                     AMAALECGERAAIRTVESLIDAGAVTSPTGEVTAHAALYEVPRLLCLYARERVGAAQ"
     misc_feature    complement(14042..14044)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15064..15078)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.13"
                     /tool="antismash"
     gene            complement(15105..18026)
                     /locus_tag="B053_RS0112360"
     CDS             complement(15105..18026)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124639.1"
                     /locus_tag="B053_RS0112360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_018488912.1"
                     /transl_table=11
                     /translation="MRATSPVIVGRDEEIGLLSSALDAVRRRSGRALFFVGEAGIGKSR
                     LVGECAYRAYGLGMPVLRGRATSTGLVVPFRPLVEALSSRFRAAGTPTDPELAPYHPAL
                     ARLVPEWRQEASPGYPETVVELAEALLRLLSVLGRESGCTILLEDLHDSDTETIAVVEY
                     VIDNLADLPILLLGTLRPEAGAALDLVRSAERRQAAGVRELKPLGDDQMRVLTGACLEA
                     APEEIPQVVHQRLAERAGGNPYLVEVLLADLLDTDQLRQSEDGWEAADDPGGPVPSGIV
                     RSWARRLDRLDEPVRELLLAAATLGGQFSVTVLQTVTGFEDRALFTHLRSAVEAGVIAP
                     DGAAPDRYAFRHSLTAEALISSLAPAERASLARRAAGAVERSGQPLDEDGQQLVASLHL
                     AAGNRAGAALRFAEAGRRMLASGAHGSAVVLLERACPLAADADRAAISESLAVAKAEGG
                     DLDAALELADALPPVPARTEAADRRGEIHIRIAWVAVMAERAADAARQIEAARALLGEE
                     PAPGRRAALGVADAHLALMPGQEHRCPSETERAAREAAEIAEAEGLPVVACQAWQLLAL
                     LLRESGFDAADACLERMLALSTDHDLPVWRVEALVRLGANAFMRTGDSSRLRSARAAAV
                     ELGALLLTQTVDGLLAMNAVLCARWDEAQEIIDRSLEASARVGNHSAHRYLLLSTATMA
                     AHRGRRRDMDRSLAAFKRAGGEQSLLVPHQLGLCKAIGALLEEDRERALEKLDAVLAWE
                     QDHPSYFYLSGSYGLRPLLRVLTGAADGAEFTAVRGSPGAQLAWNGQFLELAEAVLLGR
                     DGDRSGAARLVASFDARATPFPVARHLGLRLVADAARTDGWGEPVAWLRRAEEFFYGIG
                     VQPVASACRAALRQAGASVTQHRGGWDRIPLSLRTSGVTPREYEVFVLLPERPGNQQIA
                     RRLSISPRTVEKHMASLLSKTGRADRSALCEFAAECAVEVEPA"
     misc_feature    complement(17130..17132)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18096..18290)
                     /locus_tag="B053_RS0112365"
     CDS             complement(18096..18290)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608631.1"
                     /locus_tag="B053_RS0112365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018488913.1"
                     /transl_table=11
                     /translation="MTHISESAMQGSGNLPQDGGYDHPAGQISFGIGGGLGMRSRLLSA
                     SEGEAGNTIDLPWTTMIPL"
     gene            complement(18427..21543)
                     /locus_tag="B053_RS0112370"
     CDS             complement(18427..21543)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511315.1"
                     /locus_tag="B053_RS0112370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_018488914.1"
                     /sec_met_domain="DUF4135 (E-value: 2.8e-102, bitscore:
                     335.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.6e-24, bitscore:
                     76.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKELIGSGGTGAAARPVPPAVTVNGSTAVVHMNGTGGAHPVGGA
                     ARAAGTVRPGASPRAATDNSPRSGPWWLGGVVGEPPVGEPDWVVFVQGVIADAPPVVAV
                     PERKYPGLTGFALVVAPFAERAAARLLTSPSNNAVRAGTAVGLAPVLDDFRSQLTARLA
                     RLAARTLVLELHKARRAGRLAGEGPGERFRDFLRLTAGRDGLAAFLTAYPVLAHILART
                     SLSAADALTEMLGRLADDRELLAASGVLGDRGPTAGSLGAGPGPGALTGVDTGAGDSHR
                     GGRSVMLLRFNDGTRLVYKPRPLSAHRHFNSLVEWFGSLPGTPSLRALRVLDRGEYGWV
                     EFVAERPCSSPAETHLFYRRQGALLALLHLLDGTDLHQENLIACGPHPVLVDVETLFHP
                     PLTQAHSADPAARALHASAYRVGLLPQLLVGDSAALDVSAIGGGRAAPSPIETADWADA
                     GLDTMRLVRRSARFTESANRPRLEGVPADPSTYTDALCEGFRVGYTAVSEYRDELLGKR
                     GLLTDFARDEVRVVSRPTWTYTTLLDESTHPDLMRDAAERHQVLSLLRTPTLGTPALPG
                     LEEEEIEELWAGDVPVFLTRPGAAELWSGTGRGVPATPGPTGLERVEAKVRAMDSVDRQ
                     DQERIIRAAMVSTSAEPPHRSEGGARARTAATAPEPEHLLSAARSVGDQLVSLAYRHEH
                     RTNWIGLELLGERYWRLAPMAADLASGYTGPALYLAQLAALTGAERYAEAAREALTPVP
                     GLLDALHGRVDDLAVLGSGAFAGLGGIAYALAEVGALLDDRTVTELAGPATRLACAAGA
                     AEQGYGVRGGAAGGLVSLLTVHRTTGRAEAWRGAERCAERIAVAPLPVAGGFAEGAAGI
                     GWALLRFAAAGGGEQYRTAGLRALRRATVEVPDGGAWCEGSVGVALAVADSPAALADPD
                     LSGWLAERAGGLADRAPLADDSLCHGELGLLELLGHPALTGDRTPWVRRAGTLLAAADR
                     EGPRCGTPGHVPHPGLLTGLSGIGHGLLRAGFPDRIGSALLLNPSLGAA"
     gene            complement(21797..22882)
                     /locus_tag="B053_RS0112375"
     CDS             complement(21797..22882)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019763012.1"
                     /locus_tag="B053_RS0112375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_018488915.1"
                     /transl_table=11
                     /translation="MTVTLADVAARARVSPATVSRVLNGNYPVAASTRERVLRAVDDLD
                     YVLNGPASSLAAATSDLVGILVNDIADPFFGIMAGAAQTQIGGPGDGTGRAGGEKLAVI
                     CNTGGSPERELTYLTLLQRQRAAAVVLTGGAIEDPEHQTAMAAKLAKLADAGTRIVFCG
                     RPPLPEGDALVAALAFDNRGGGRRLTEHLISLGHRSIGYVAGPPERTTTRHRLEGHREA
                     LRGAGLDGGDGEGVDGGRLTVHGPYDRRSGYEATLDILRREPGITAVVAANDTVALGAC
                     AAVRDQGLRIPQDISVAGFDDLPFSVDAVPALTTVRLPLFEAGARAGRLAMGKENPPPG
                     GIATIAAELMIRGSTAPPRVG"
     misc_feature    complement(22878..22889)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 14.95"
                     /tool="antismash"
     misc_feature    complement(22958..22969)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     misc_feature    22961..22981
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     gene            22993..24144
                     /locus_tag="B053_RS0112380"
     CDS             22993..24144
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005317389.1"
                     /locus_tag="B053_RS0112380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_032779902.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 6.5e-10, bitscore:
                     32.8, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.9e-27,
                     bitscore: 88.8, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRTVRIAMNGVTGRMGYRQHLVRSILAIREQGGLDLGGGEVLW
                     PEPVLVGRRAHALEEMAALHGLTEWSTDLDAVLADDTVEIYFDAQVTSARVESVKRAVA
                     AGKHIYTEKPTATDVEGALDLARLAREAGIKHGVVQDKIFLPGLLKLKRLIDGGFFGEI
                     LSIRGEFGYWVFEGDWQEAQRPSWNYRAEDGGGIVVDMFPHWEYVLHELFGRVTSVTAQ
                     VHTHVPRRWDEHGEPYEATADDAAYGIFQLAGGAVAQINSSWAVRVNRDELVEFQVDGT
                     HGSAVAGLRNCRVQHRSSTPKPVWNPDLPVTEPFRDQWQEIPDNQEFDNGFKAQWELFL
                     RHVVLDEPYTWDLLAGARGVQLAELGLKSSAEGRRLDVPELTL"
     gene            24141..25313
                     /locus_tag="B053_RS0112385"
     CDS             24141..25313
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019763010.1"
                     /locus_tag="B053_RS0112385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_018488917.1"
                     /transl_table=11
                     /translation="MTASASASAPVPLPQGPYTPRATPLELPAGGAPLTSRTVYSAAHV
                     VADPYADTGPDGPAAVDWESTLAFRRHLWSHGLGVAEAMDTAQRGMGLDWPGAAELIRR
                     SAAEARAVGGRIACGVGTDQLLLTSEPTLAEVTSAYEEQLALAEANGVQPILMASRALT
                     RAARGPEDYLATYAHLLRQSGEPVILHWLGPMFDPALEGYWGSADLDEATDTFLKVIAE
                     HSDKVDGVKISLLDAAREIDVRRRLPSGVRCYTGDDFHYPELIAGDEQGFSHALLGIFD
                     PLGPLAAHAVRVLDTGDVDGFRALLDPTVELSRHLFRPPTRFYKTGVVLLAWLAGHQDH
                     FTMVGGLQSARSLPHLARAYQLADGLGLFPDPELAAHRMRALLEVQGGTR"
     gene            25310..26179
                     /locus_tag="B053_RS0112390"
     CDS             25310..26179
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608626.1"
                     /locus_tag="B053_RS0112390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_018488918.1"
                     /transl_table=11
                     /translation="MTTAQTPAPISAPTASLARLSINQETIKQWSLPELAEGCVKAGIG
                     QVGLWRAPIQAYGVERTARLLSDAGLTVTSLCRGGFLTALDPAARALALDDNRRAVDEA
                     AAVATDTLVLVSGGLPPGSRDLYGARERVAEALAELAPYAAERGVRLAIEPLHPMFASD
                     RCVVSTLAQALDLAERFPAERVGVVVDTYHLWWDDRAPAEIARAGAGGRIHAFQLADWI
                     TPLPAGVLLGRGQLGDGSVDFRAFRAAVEAAGYDGPIEVEIFNEELWARDGAEVLAEVA
                     ARYGQHAC"
     gene            complement(26377..27336)
                     /locus_tag="B053_RS0112395"
     CDS             complement(26377..27336)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018381499.1"
                     /locus_tag="B053_RS0112395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="WP_032779934.1"
                     /transl_table=11
                     /translation="MGGADPTVIKVGSLYVSAKAVDGGIAVRTASTAEGVATAPKHQVW
                     RDTGNLGEVWAPEIVHHAGQYRIYFAAGRGAAHRMYHIGSATPTSGYSAAVKVSLPADK
                     WAIDGVPFTFNGQRWFVWSGWSGDTNVEQNLYIARMSSPTAATGGRYVISQPREPWERV
                     VGNPYINEAPQPIVDPQGRLHVVYSANGSWSNKYCIADLRLRAGGDPTYVWDWYKSNGC
                     LFGSHAPSMMSGWTPTVNVDGPGHQTFVLPQGDVNEGPPSGNRFPTLYHAVAKGTPYTW
                     SNRHWYSGTAVWWGSTTYRRANVPGSPTDVGHSLKFFE"
     CDS             27383..27589
                     /gene="allorf_153271_153477"
                     /locus_tag="allorf_153271_153477"
                     /protein_id="allorf_153271_153477"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDAGRSVDAGRSVARCTGWAAVAVCPSASRAASPSVTAPASRREG
                     GMGVLLAGARRRGCERLSAGARA"
     CDS_motif       27383..27541
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MDAGRSVDAGRSVARCTGWAAVAVCPSASRAASPSVTAPASRREGGMGVLLAG"
                     /locus_tag="allorf_153271_153477_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       27542..27589
                     /prepeptide="core"
                     /locus_tag="allorf_153271_153477_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.60"
                     /molecular_weight="1611.8"
                     /monoisotopic_mass="1610.9"
                     /core_sequence="ARRRGCERLSAGARA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDAGRSVDAGRSVARCTGWAAVAVCPSASRAASPSVTAPAS
                     RREGGMGVLLAG"
                     /leader_location="[27382:27541](+)"
     misc_feature    complement(27590..27604)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.03"
                     /tool="antismash"
     misc_feature    27591..27605
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.16"
                     /tool="antismash"
     gene            27825..29516
                     /locus_tag="B053_RS0112400"
     CDS             27825..29516
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384873.1"
                     /locus_tag="B053_RS0112400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 76 protein"
                     /protein_id="WP_018488920.1"
                     /transl_table=11
                     /translation="MPPTPRPVSFGPVRPALCAAVALMLGVLPAATARAAGPAAPPPSV
                     APSTAAAPPPSAALSTVAAPPASAVAPPSAAPQVPLPPDRSERSGRAEPGGEPSRPTVA
                     ADGSAVSAALCNKHCDARDPAAATSDRVPVTASLHGRSIALHLSDNDVMGWASIDNGQA
                     GDQTWLDRSFDGGRTWASGSRLGATAIPAGRTGWRSQMYNVDDWNSGGIGALRACGKAG
                     DRAEIACTGWARVDWNAGSRSKAAATALMMNYDRASGKFAGWWTSATALTSLIDNIRIS
                     HMPSYRYAVANTYDKLRTAEGGDFTNSYLDDTGWWGLAWVAAYDLTGDRRYLDTARKDA
                     DHMAAYWTDKCGGGVQWATDKAYKNAITNELYIQLNAALHNRLPGDTTYLRRATTGWDW
                     FRNSGMINSGNTVNDGLRDDCTNNGDTTWTYNQGVILAALAELHRATGDASLLARARTL
                     ADASTTSAYLNPGGTLHEPYEPDGTGCTSDGDSFKGAYVRGLGLLNKALPDRPYSAYLD
                     RQADTAYAKNRNSLDQYGPHWAGPRTVTGNGCQHSALDLMNAAEDS"
     gene            29697..30488
                     /locus_tag="B053_RS0112405"
     CDS             29697..30488
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018488921.1"
                     /locus_tag="B053_RS0112405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NPP1 family protein"
                     /protein_id="WP_018488921.1"
                     /transl_table=11
                     /translation="MPRSAHRPTRRGRVLRRGLTVTLTAAALVLTTATMAHAAPPPPLP
                     GNADDLERRFQPALDYDKDGCYATSAIGPDGTIAPGLKLGGALNGDCRDLSDLENSNAY
                     SRAKCDNGWCAILYTYYFEKDQVAPGGLFGGHRHDWEHVVVWVHDDKAQYVATSAHGNF
                     AVHKAADVPFDGTHPKVVYHKDGASTHCFRKATAKDEPPENHYGTWHYAPLVGWNGYPD
                     GLRDKLLAADFGKATIGIREDRFTGHLTKALPKGVPFNPAS"
     CDS             complement(30880..30987)
                     /gene="allorf_156768_156875"
                     /locus_tag="allorf_156768_156875"
                     /protein_id="allorf_156768_156875"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVRLGALVPYSIRWTVLRSIPVGSPRCICVRRRSS"
     CDS_motif       complement(30919..30987)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVRLGALVPYSIRWTVLRSIPVG"
                     /locus_tag="allorf_156768_156875_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(30880..30918)
                     /prepeptide="core"
                     /locus_tag="allorf_156768_156875_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.10"
                     /molecular_weight="1365.6"
                     /monoisotopic_mass="1364.7"
                     /core_sequence="SPRCICVRRRSS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVRLGALVPYSIRWTVLRSIPVG"
                     /leader_location="[30918:30987](-)"
                     /alternative_weights="1383.6"
     gene            complement(31070..31207)
                     /locus_tag="B053_RS1000000137145"
     CDS             complement(31070..31207)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018488922.1"
                     /locus_tag="B053_RS1000000137145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018488922.1"
                     /transl_table=11
                     /translation="MAKEWTDPRYADLVAAWKAGQEPDSRDPDEPRPVRGFLIPTKPEA
                     "
     gene            complement(31230..31463)
                     /locus_tag="B053_RS01000000133875"
     CDS             complement(31230..31463)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B053_RS01000000133875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_018488923.1"
                     /transl_table=11
                     /translation="MSSSLPADVAAHFPGYDPTHYDPAILDRTRQAITSLGYVPDAKLW
                     GEPSDETLVAVAARCQHAPECTIRPMPKPEWP"
ORIGIN
        1 cccgttggag ggaggagagc cccggatgta cgggctcctc ggggtgggcg cgcagttcca
       61 cgccctggta cccgtggtcg gcggcgagcc ggacgacctc gggcagcggc atgcccggca
      121 ccccgagcgt ggagaaagcg agcttcacgt gtgcgtcctt ccgtcgtcgc cgcgcgggag
      181 cccggcgccc ttcccccggg ctcctgcccg ccgtccggga cgctatgcgg tgccccggag
      241 cacctgctcc aggctaccca gcagccgcag cgcgtcctcc cgttcggcgg cctccagcgg
      301 acgcgccgcc ggagccgcgg ccgccggttc gggggtgatc acccgcaggg ccgccgccgc
      361 ctgccgggcg aacatcgcca gcaggtccag ctcccgcacg ctgctcctgg cctgcggtga
      421 cgcgtccagc acctccagga cgccgaggac ccgggagtcg ctgatcaggg gggccgccat
      481 cagggagtcg gggacgtact ccgtggactc cgccagcgag cggtcgaacg acgggtcgtc
      541 ggtcaggtcg tccaccacca tcggctcgcc cgaggtcgcc acccagccgg cgatgccccg
      601 cccggccggg aaccggcggc ccaccaggaa ctcctggccc tcaccggaga ccgcccggaa
      661 gaccagctcg tccgcctcct cgtcgagcag cagcacggag cccgccgccg cgccgaagat
      721 ggcccgggcg acgtcgacga ccgactggag cagttcgtcg cggtgcgcgt cggaggggga
      781 cgcggcaggc acgggggcgg gggagagggc ggaatcagat ttcggcgtca tcgtgggtgt
      841 ctcctgccgc tgttgaagga cgcggggcat ggtcggctgt gctcgggtcg tggcggacgt
      901 tggccgccga cagatagagc gcgttcttga gctggaaggc cgtcatccgc gggtgcgccg
      961 acagcaggcg cgcgcagagc ccggccacgt acggcgtggc gaagctgttc ccggtggtgc
     1021 ggatcgtccg gccgcccagc cacggcacgg tcacgttctg gcccgggccg aagaactcca
     1081 ccggcggggc cgggttgtag aggtggagat cggggtcgtc ctcctggtgg ctgcccacgg
     1141 agatcaccga agcgaaccgc cacgggaagc tctccaccgg ggtgttgtgg gccgaggcga
     1201 cgatcaccgt acgggcgaag taggcgctgt ccgccagcga gtgcagctcc tgcgcgaacc
     1261 gggtccgggt ggtcgacagg ctcaggttca ccacgtcgaa gcgctgctcg accgcccacc
     1321 gcagcccggc catcaggatg tcgcccgtgc cggagaaccg ttcccccagc acccgtacgc
     1381 tgtggatctc gcactccggc gcggtccggc ggatgatgcc cgcgcacgcg gtgccgtggc
     1441 cgcaggtgtc gcccgtcgtc gtcggctcga ccgtgatctc cccgctctcc ccgtccttga
     1501 cgaccaccca ggacgaggcc ggttcgccga ccagcggatg gtcgcgttcc acgcccgagt
     1561 ccaccacgca gacgcgtacg ccgcggccgg tggcgggggc cgcgggctgt ccgcccggcg
     1621 gccccggatc gcccagcacg gggacgtcct cggggccgcg tccgcgcagg ctccaggtca
     1681 ggcccagccc cggggccgta cgagccgcgg gggccgcggg ggccccagtg gccgcagggg
     1741 ccgcatgagt ggtcactgtc gtcgtctctc tcgtggtgcc catcgggtca gctcccctcc
     1801 ctcaccgtga tcgtcgtggc caggtcggcc gtggtcaggt ccaccccggc cgtgtccgcc
     1861 gtgccggtgc ccgtcgtgcc tctgtcagcc gtggccgtgt ccgccgcgac cgtcccggcc
     1921 gtggccgtgt ccgtcgtggc cgtgtccgtc gtggttctcg tcctcgggcg gtgcagcgcc
     1981 gtgcggaacg cggtcgcccg gcgcgccccc ggcagatggc ccttgcccgt gaagtggtcc
     2041 gccgcgctcc gggccgccgc ctccgccgcc gccgtgagcc ccagcgtggc gagcgtgcgg
     2101 gcccggtcca gttcggcggt ggcctgtacc agcggtgagt cggtgagcag ggaggcgcgt
     2161 acggcccggt cggcgtggtg gagcgcctcg tccgggtgct cccgggccgc cagccgggcc
     2221 cgcagcccct ccaggtcgac ggcgtccgcc ccgctcagcc ccgacggttc ggccaccgtc
     2281 gccagccact ccaccgcccg gccctccgcg cccgcgtcca gctccagccg ggccgcgtcc
     2341 agcgcgacgg ccgtccgcat gcccgccgcc ccgacgcgcc gggccgccgc gtccgcccgg
     2401 gccagcagtt ccagggcctg cgcaccccgg ccgagcaccg cctccaccgt cgcccggaac
     2461 accggaagga acacctcggc ctccgcgaac cccagcttcc ccgccagccg ttccgcctcg
     2521 gccaggcacg cgtacgcctc gtcggaccgt tcctggagcc cgtacagcac ggccagcggg
     2581 cagttgagcg tcacccgcac cgtcggccgg cccgcgccgt gggccgtcag cagggcgcgg
     2641 cagcgctcca ccgcctccgg caccgggacg ggaccgcgcc agagggagat cccgatcgcg
     2701 cccagcgccc cggcccgctc cggctccgcc ccggccgcca ccgcgtgctc cagggcccgc
     2761 gcgtggtcgc gctccgcctc ctcgtggcgg cccgactgct ggagtcgctg ggcgaggcgg
     2821 aggtgggccc gggcccggcc gaccgcgtcc ccggcggcct cgaagaccgg cagcaccgca
     2881 cgggccgtgg cggcgggacc ggggggcgcc gtcgggtcca gcaccgccag cgccagccgg
     2941 gcgtgcgccg actcgaccgg ggcggtggtc aagtccctta cgttacgcag cagttcggcg
     3001 ccctcctcgg tccggccgag cgccacccgc acctcaccga gccccagcac cgcccgcgcc
     3061 gcgtccggcc gcagctccac cgcccgctcc agcagcccgt gcgcccagtg caggtcggac
     3121 cgggcggcgg cctgcgcacc ggcccggccc agcgcggcgg cggcgcggtc ccgcagctcc
     3181 tgggcccggt cgtccagcag ccccagctcg gcgcggtagc ggtaggcgcg ctccagatgg
     3241 cccccgaccg cgccgtcccc ggtccgggcc acgctcggca gatcggccgc ccacgcgtgg
     3301 cgctccgcct tggcccgctt ggagagcgag gagtaggcga cctcgtgcac cagtccgctg
     3361 ctgaaccggt acgccgacgg gtccccggcc ccggacggcc gcgcgggctc caccagccgc
     3421 cgccgggcca gctccgccag ggcctcgtcg acgcggtgcc ggtcctgtgg ggtggtggcg
     3481 gggccgtcgc cgccgtcggc cgccgcaccg ggcccggcgg ccgtcacccc ggggccgtcg
     3541 gccgccgcac gggcccggtc cggcgtccgt gccgactgct ccgtgcgtac cgtctgctcc
     3601 aggcggacca gctccgccgc cgcgaactcc cggccgatca ccgccgccag gtccaccacc
     3661 ccgcgctcgg gccgggcgag cgcgccgatc cgggcgccca acagggcctg gagcgtgggc
     3721 ggtagctcgc ggtcggggtc cgacggggtg gtggccgcgc ctgggccgcc gtccgggagc
     3781 tgttcgccga ccaggagctg ttccaggtag agcgggttgc cctcggcgcg ggcgaggaga
     3841 cgctcgtcgg ccggggcgga ctttccgtcc aaccgggcca gtccggcggc cagtcgggcc
     3901 gcctcctcgc gggggaggcc ggagaggtgg aggtgcgccc ggccctcggg cataccgtcc
     3961 gggcggcccg cgcagatcac cagggtgcgg gcggggccgg tgtcccccgc cagccgctcc
     4021 accgtccgca cgagcagggg tgccgccgca tgccagtcgt cgaggaccag gaccgcgggc
     4081 cgggtgcggg ccgcccgctt caggaccgcg gtcagcgccg cgcacatgtc ctcgaagggg
     4141 gcgttgggag tgccgtcgcg caggagcccc ccggagagca gggccatcgc gtcggccgtc
     4201 gcctcgtcgt cgggtgtgtc ggcgtcctgg ggtgtgcccg tacgcgggtt ggcgtccgta
     4261 tgcgggtggg tgcctgcggg cgcgtcggcg tccctgtgcg ggtgggcgtc cctgtgaggg
     4321 tgggcgtctc cgtgcgggtc ggccgggtcg gccggggcgt cggtctggga gagcagggag
     4381 cgtacggcgt cggccagggg ggtcagcgtg ccgtggtccc cgtaggtgcg gcagcggccc
     4441 gccccgtgac ggaacgcgcc ctccccgccg tggtgcgtca gccactcccg tacgagccgg
     4501 gtcttgccga tgcccgcctc gccggtcacc cgcagcagac cggggtggcc gttccgtacg
     4561 gtcttctcca aggcctggtc cagtgtggtg agttcggcgg cgcggcccac gaagggcgcg
     4621 tcgaagcggc gcagcagctc ggggtcgtcg gcgcccagcg cgagcagccg gtacgcctcc
     4681 acgctctccc gcttcccctt gagccggagc gggccggtgg gtacggcctt caccgtgggt
     4741 ccggcggcga gcagggtctg cgggccgatc aggatctcgc cggggcccgc gttctgctcc
     4801 aggcgcgcgg cgatgttgac gacctcgccg gaaaccagcg cctgccgggc cgtggcgtcc
     4861 gaacccgcca ccacctgacc ggtgttgacg cccacgcggg tggtcagtcg gatgccgagc
     4921 gaggcgtcca gctcctcgtt cagggcgtcc agcgcccggc gcatcccgag cgccgccgcc
     4981 agcgcgcgcc gggcgtcgtc ctcgcggacc accggcaccc cgaacaccgc catcaccgcg
     5041 tccccgatga acttctccgg ggtgccgccg cgcgccacga tctgggcgct catcgcctcg
     5101 aagtaccgca gggtcaccgt gcgcagggtc tccgggtcca gcacccccga cagcgcggtc
     5161 gaccccacga gatcgcagaa cagcacggtc accggcttgc gttcgtcctc cgggggaggt
     5221 gcgacggggg cgggcggagc cgccgctgcc ggaccggcgc acggtgtccc gcaggacgag
     5281 cagaaccggg ccgtggcggg aaggtcctgt cggcacgagg ggcagatcat ggcgggtcct
     5341 caaggggtcg tggtccacat cgtgggtcaa ctcggccagg gccggggcca gggccagggc
     5401 cggaccggat ccggggccag gtccggggcc gggtccgggg ccagggccgg ggtcaggtcc
     5461 cggcaggtcc ggctccggtt ccggtatcgg gtccggggtc aggtcccggt aggtccggta
     5521 ccgattccgg ctccgggtcc ggctccgatt ccggctccgg gtccggctcc gattccggct
     5581 ccgggtccgg ctccgattcc ggggccggag gtggtgcggc cggccgtcgt ggccggccgc
     5641 accggccccg ccgcgccgga cccccgtcct ggcgcggaca cccggggggc cgcagcggtg
     5701 cgctcagaac agggcgccgc ccgcgatctc gccgtgggcc tggacctcgg ggcccaccgc
     5761 gtccagccgg ctcttgacgt cgagcagcag ggtcagctcc tgcgtcgtca actcgcccag
     5821 caccaggcgc tgttcatcgg tgaggaggtc caccgggaag cccgccgcgt gcagcgtctc
     5881 ctccaagggg gacgtatccg gggacgacgt gcccagggag tgcgtgccca gggagggcgc
     5941 gttcagaggg gacgtgcccg agggaggtgt ccccaaggag gccatgtccg gggagggttc
     6001 gggggtgggt ggtggttgtc cggtcatcgg gtgactcccg tcggtggggt gggtccggct
     6061 ccccgcagcg acggcgccgg tgcggagcgc ccgagccgga cgaacagccg ggtgagcgcg
     6121 tcgaaggagt gcagggcgct gaccgcgacg gccgcctcct ggccccgggt cagcggcagc
     6181 cggtccagca gcgcgtacag ctcgtccaga tgcccggtgt cgagcgccgc gtgttcccgt
     6241 acggtccgca gggcggcggc gggcagcccg gtcagtccgc cgatgcggtc ggtcagcccg
     6301 ggcgcgggcg cgtacccctc cagcacggcg atgtagccga gcagggccac ggggtggtgg
     6361 tgctcgatcc agtagtactg ggggccgacc agggcggcca catccggcgg cggcaacggc
     6421 ccgagcgcgt cctcgggggc cgcgcccgcc gcgcgcagat cctccagcag ccaggcgtcg
     6481 tgctccgcct cctcctggat gtgctcggcc agatacgcgg tcagcggccc ggagagcgga
     6541 tcgccgggcc ggtccgccat gcgccgcagg gccagctcca tcagcgggac cgaggcgcgg
     6601 atcacggcgt gcatggtgca caggtaggtt cggtagcgct ccaacagccc ttcggggcgc
     6661 cacatatggc tggtcgctcc ccggaactcc ggttcgagga gaaggagttt ggtgcgcagg
     6721 cgcgccgaga cgtccatggc cgcggtggtc accgcatgct cccggccccg gtgcggaccc
     6781 cggtcccagc cccggcctcg ctcccggtgc ctgccgcgtc ggccgccgcc tcggcccccg
     6841 cgcccaccag ccgcgcgtac gccgagcagc cgtgccgccg gacgaccccc tcgggcccgc
     6901 ccagcgcacc gcgccgggcc gccgccaggt cgagcagcgc gcccgccggg ccggacgcca
     6961 ccgcgcgggc cccggccgcc accgcctcgt tcccgcccag cgcgcggcac ccgtcgcagt
     7021 aggagccggg ctggggtgcg gcgccggagc gggcggccag atgggtcggg ccgaccgtac
     7081 ggatcatccg caacaccggt gattccaggg cccgtcggcg tacggccgcc cagtcgtcgg
     7141 agccgatgtg gccgaggtcc agatgggccg gggcggggcg ccggtccacc gtgtcctggt
     7201 tgcagcaggc cagcaccgta ccgtcgaagg cgaccgccgg ccaggcggcc atcgagcagg
     7261 gtgccgccgc cgacgggtcc ggtccggtgc gcgcggggcg ggcccaggag gcggcccggc
     7321 cgaacggccg cacctcgttg accagggacg gcacccggcc gccgaactcc ttgtcgatcg
     7381 cccgggtgat gtcggccaga tacgggtcgt ccgcacccgt ccccgtgagg tggaagctca
     7441 cgctcacccc cgactcgcgg atgtggtgca gggcccggaa cacctccgcg cgcgccacct
     7501 cccgctcgtg gtacacgtcc aggctcgcgg agaagtggtc gacctgggcg atcgcgcgca
     7561 ggatcgcggg cgggatccgc cgcgagcggg cgaagaacat cccgctcagc accgccgtac
     7621 gcgatccggc gcggcgggcc aggaagctca gctcgcccgc gagcgtgggc aggagcagcg
     7681 gctcgccgcc cgtcagcatg acgacgtccg gccggttctc ggtggtgaac gagccgacga
     7741 atcgcagcag ttgggcggcg ttcggctcct cccgcacggt caggtccgac ccggtggagc
     7801 agtgccggca gcgcaggggg cagcggcggg tgaggccgag cagcagaccg gcggccggga
     7861 agggccgcag tccgacgagt tcggcgagtt ccatacgggc cgcctccttc ggggccgggg
     7921 gcgcggcggg cgcacgccca ggctggggcg gaccggttca cgggcggtcg gccgacgctt
     7981 cagggtcggt atgggcgcag gtcagcgcgg tccgggggag ggccggacgg ccggcccggg
     8041 cgcccttcgg tcactgcgcg ctggccttat accggcccca taccggcgtc gaagcgtctg
     8101 gcaggcggcc gttcctactg ttctcggcaa cggcaggcac cggaccgcgg cagacgccac
     8161 ggacaccgga ccggcccacc ccgagtggac ggagaccacc atgtccgaga acaccaagcc
     8221 cgccgccgac gagaacaacg agaccgagac ccccgaggtg gaggcgcact ccgtgctgga
     8281 cctccaggag accccgggcg tcatcgaccg cgagatcgtc cccggcaact gcgtcagcac
     8341 cgtgagcctc gtcctgagct gacccagggt ccactggggc gtgcgccacg gcggcttcga
     8401 acccgccgtg gcgccggccg ccggagtcgg ggcggcctcc gtacaccacg gaggccgccc
     8461 cgccccgcgt acgggcccgg attccggcct ccccgtgtac gggaccgagc cccggcgtac
     8521 gcgattgagc cgccgtgagg atccgagccg acggacgggc ccggccccca cccgtgggtc
     8581 ccgcccccct ccgcgtaggg gaccgggacc acccgccgcc ccaccccgcg cacagccgac
     8641 gacccgacga acaacgggag cccccgatgg ccacgccgct ccgctccaac cgggatttcc
     8701 ggctgctctg gttgagcggc ctcttcgccg ttctgggcag ccagatgagc gccctcgccc
     8761 tgcccctgct ggtcctcaag atgaccggct ccgccgtgca ggccggtgcg gtggggacgg
     8821 tctccgtctg cgccctgctg gtgacgatgc tgcccggcgg ggtcatggcc gaccgggtcg
     8881 agcgccgtcg gctgatgcgg ctctgcgacg ccggaagcct cgccgccgtc acggccctga
     8941 ccatcgcggt ctggtacgga cacgccccca tggtgctcgt gctgctggtc gcgacgtcgg
     9001 gagccgtgct gagcagcgtc tacggccccg ccgccttcgg cctgatgcgg gcggtcgtcc
     9061 cgccggacca gatgggcacg gccaccgcac ggctccaggc ccgtacctcc acggtcaaga
     9121 tggtcggccc gctcgtcggc ggagggctgt tcggcatcca tgaggccctg cccttcgcgg
     9181 cccagttcct cggactgctc ctctcgaccg tctgcgtggc gctcgtgcgc acccgctccg
     9241 aggcgaggag ccgggccggt tcggtcttca gccgccgcga actcaccgcc gggctcgcct
     9301 tcctctggca actgccgtat ctgcggaccg tgttgctcgt cttcggcctc ggcatgaact
     9361 tcgccttcgg cgccctcacc ttcacggcgc tcgccgtttt ctccgacaac ggcgcctccg
     9421 gcctcggcgg cggcttcgtc ctcacctgcg tctcggccgg ctcgctcgcc ggggcgctga
     9481 tcgcgccccg catcgccccg gaccgccacg cccgcgccct gatcgtcgcc acctgctggg
     9541 cctgcgtcct gacggccgcc gcgctggcct ggctgagcag cgcgctgctg gccgggctgc
     9601 tctgcgcgat ctgcatgtgc ctctcgacgg tcgccagcat cggcttcctc tccacgctgc
     9661 tgatcgtcac cccggaggac cggatcggcc gggtgcagag cgcggcgggc ttcctctcct
     9721 cgatggtcca gccgttcggg ccgctcgcgg gcggggccct gctgacgctg ctcggcagcc
     9781 gtatcgcctt cggcaccatc ggctgtgtgc tggccgtctc ggcggccgtg gtgacgctcg
     9841 ccccctcggt acgggcgggt gcggcggcca tcccgtcgcc cacggagccg gaggggctgc
     9901 ccggcctgaa gccggacccg aagcccgaac cggagcccgc cggaacgtcc cgccccgccc
     9961 ccgaccccgc cggtcccggc gcgcactgag gagagccacc gtgtccgtct ccggtatcca
    10021 gcagacccag ctctactgcc tcgccgaccc cacctactac gagaccccgg cccgcctccg
    10081 cgacgaggag acccgctacc ccctggactc cgccccgccc cccgagggca ggcgccgggt
    10141 ccggaacggg ctgtggacct cgctgctccc cgaggaccgc gagatcgccg agcagggctg
    10201 gaagatccac atctccaccg tcccggagga ggccgaggcg accctgcgcg acaccgcccg
    10261 gatctgcctc gcccacggcg taccgttcaa gttcctccgc agcgagcagg cgctcctgct
    10321 gatgtccgac aagtacatgg cccgctccgg cgccgggaag ttcctcacgc tctacccgcc
    10381 ggacgagacc gtcttcctgc gggtgctgga cgagctggtc ccggcgctca ccggacgccg
    10441 gggcccgtac atcctcagcg atctgcggat cggggacgcc ccggtctacg tacggtacgg
    10501 agccttcgtc gcccgctggt gcctggacgc cgacggggag cgggtcccgg ccctgcgcca
    10561 cccgtccggt gaactcgtcc ccgacgagcg gggcgtggtc ttccgggtgc cgccgtgggt
    10621 caccgtcccc gaaccgctgc gcccgcacct cgcggcccgc gccgccgccg gggacaccac
    10681 gttcccgtac acggtcacgg agtccctcca gttctccaac gcgggcggga tctaccgggc
    10741 ccggcaccgc gagaccggcc ggcaggtggt gctccgcgag gcgcggccgc acagcgggct
    10801 ggacgcggtg gggcatgacg cggtgacccg gctgcaccgc gagtaccggg cgctgaccgc
    10861 gctggccggg ctggactgcg tgcccgaggt ccacggcgta cggagcgtgt gggagcacca
    10921 cttcctgatc gaggagcaca tcgaggggtc caccctcctg gaggagatcg tcgcccgctt
    10981 cgccctcctc cacggtgcgg gcacggacgc cgaactcgcc acctacaccg cctgggtgga
    11041 ctccgtggcc gagcggctcg cccaggcgct ggcggcgatc cacgcgcgcg ggttccgctt
    11101 cggcgacctc caccccacca acgtcatcat ccgccccgac ggccggctgg tcctcgtcga
    11161 cttcgagtac gccaccgacc tcgacgacca ggacaccccg gtcgccggtg caccgggcct
    11221 ccaggcaccc accgggacgc ccggcgccga gtccgacgcc tacgcgctct gggcgacctg
    11281 gctctacatg ctgatgccga tcatggagat ggccgggcac gaccgggcca aggcggtgac
    11341 cctggagcgg tgggcccgca ggcggtaccg cctggcggcc gacgcgggcc ccatccggcc
    11401 cgccgcgctg cgggccgcgg aggaccgcct cggcggcgag ggcgagatcg ccgcgctgct
    11461 cgacgggccc gtccccgact gggcggagct gcggacccgg ctgatcgcgg gcatccacgc
    11521 cggggcgacc cccgagcgca ccgaccgcct cttccccggc gacccgcagg ccttcgcgac
    11581 cggcggcggc gacctggcgc acggggccgc cggggtgctg tacgccctgc accgcgtcgg
    11641 tgcccccgtg gaccccgcct ggaccgactg gctctccgac gccgcccgcc gccgtgaccc
    11701 ggccgcaccc ggcggactct acggcgggct gccgggcacg gcggtcgtcc tctccctgct
    11761 cggccgcgcc gacgaggggc gggaactctt cgaacgggcc gccgccgcac cgccgtccgc
    11821 ctcggccgac ctgctgaacg gccgcgcggg catcgccctc gccgccctgc gcctggcccg
    11881 gccggggggc gccgggagcg ggcggcccgc cgccgcggcc ggcccggtca ccgcggccga
    11941 tcccgacgcc aaggtcgacc acgatctcgt cgagctggcc ctgcgcaccg cccacgacct
    12001 ggaccgcctg gtccgcggcg aatccgtacc ggggctggca gcacctgcct cggccgggct
    12061 gctgcgcggg ctcagcggcg ccgccctgct ccacctcgaa ctccacgccc tcaccggtga
    12121 cgaccgccat ctgcgggccg ccggccgggc gctggagcgg gaggcggggc actgtgtggc
    12181 gatgccgggc ggcacggtcc aggtgaagga cggccgccgc catctgctct acctggacca
    12241 gggcagtggc ggcgtcgcgc tggtggccca ggcgtatctg gcccaccgcg ccgccccctc
    12301 gctggcggcc ctgctgcccg gggtccggcg gggctgcacc ctcgaattca tccgcgagcc
    12361 ggggctgttc accggccggg cggggctcat ggccacggcg ggccagctgt cgcccgaggg
    12421 ccgccgggcc cccgacgtcc tcgcctccgt acggaacctg tcctggcacc tgctcgccga
    12481 ggaggaccgg ctgctggtcc cgggcgcccg gctgcgccgc tgctccgccg acctggcgac
    12541 gggcgcggcg ggcctgctgc tggccctgca cttcctctcc ggaggcggta cggggacggg
    12601 cggggcgggg accggggcga cgggggcggg cgcggccggg acggggacgg acgggacccc
    12661 cggcctgctg gaactgctca ccctggggtg acggaccggc cacggggccg gacggatcgg
    12721 gacggggggc gagaccgaga tcaggacgga gaccgccacc gatagcgacc ccgaccccga
    12781 ggccggaccg cgaccgcagc cgacgccgga acggagaccg aagccgggac cgaggccagg
    12841 gctgggccag gaccaagacc gggccggacc aagaccgggg ccgggaccgg cggggcccgg
    12901 cccgcgcggt cccggtccct tccccgtccc ggcccccgcc taatgcgcgc cccacctcac
    12961 tgcgcgcccc acctcactac gtacccccac cccactgcgc acccccgccc cactgcgtac
    13021 ccccgcccta ctgcgccgcc cccacccgct cgcgggcgta cagacagagc agccgcggca
    13081 cctcgtagag ggcggcgtgc gcggtgacct cgcccgtcgg cgaggtcacc gcccccgcgt
    13141 cgatcagcga ctcgaccgta cggatcgccg cccgctcccc gcactccagc gccgccatcg
    13201 ccccgtccag ggtgatgccg ccctcctgcg cgggcccggc cagccgcccc agcgcccgcc
    13261 ggtcgtcggc cgccaggtcc tgccagcccg acgccatgcg ccgccgtacg gagacgtccc
    13321 cggcgaccag ttcgtccagg gccgccgacg ggtcgcccag ccggtccgcg aactccgcca
    13381 gcggcagatg gcgcagcacc gccagccgca tcccgctcac ccagaccgcc agcggcagcg
    13441 ccccgcaggc ccggacgatc cgcagggccg ccgccgggtc ggtccgcagc cggccgggcc
    13501 cgatcagctt gcccagcagc tccagcgcct cggcgtccgc cagggcggcg agggcgatcc
    13561 ggtgcacggg ggcgaggccc ggcagctggc cgcgcgcggt gagcaccacc gaggacgggc
    13621 cggaggaccg gggcagcagc ccccgtacgg acgcctcgtc cggtacgtcg tcgaggacga
    13681 tcaacgcccg gtgcagcgac agccactcct gccaggcgtc ctccgccccc tgcgacaccg
    13741 ccaccgcgac ccccaccgcc ggaacgacgc ccgcagcgcc tcccggcacg cctccggagc
    13801 cgcccgtcac ccccgggacg ctccccggga cccgcacccc gcacaaccgg gccagttcgt
    13861 ccaggacttc ggcgggcgtg cgggcggagc cgtcctcccg gcggaccccg acatggaagc
    13921 gcccgtcggg gaagctgtcg ccgagcagat gggcggcccg cagcgccagg gccgacttgc
    13981 cggaccccgc aggacccgag acgaccgcca cccgctcgtc cgcggcaccc aacagcccca
    14041 ataactcgcg cagttcctca cggcggccgg tgaaatggcg cggcgcggcg ggcagggccg
    14101 taccgcgcgc gctctcccgc ccgcccgtcg gcggccggtg ggtgcggccc cgccccagca
    14161 tcaccttgta cagggcggcc atcgccgggc tcggttccag gcccagctcc cgggccagca
    14221 gctgccggta gtcgtcgtac accgccagcg cctcggcctg ccgcccggac tggtgcaggg
    14281 agttcatcca ggccacccgc agccgctccc gcagcgggtg gcggtccacc agatcgcgca
    14341 ggccgtcgac cgccgccgcg ccccggccca gctcggtctc gatctcggcc cagtcctcgt
    14401 agacggtcag acagcgggcc tccagccgct cggcctcctc cgccaccccg gtggagtccc
    14461 gcaggtcgtt cagcggcggc ccctcccaca ggtccagcgc ctcccgcagc agccgggccg
    14521 ccgcccgcag atcgccgcgc tcaccggcgg tccgcccggc gcgggccagg gaccggaagc
    14581 gcagggtgtc caactcgccc tcgccgatgg tgagccggta gccgccgcag ccgtggacca
    14641 cccgctcgcg gtcctcgtcg ccggtgctgc ccagcagggt gcgggcggcg ctcacataga
    14701 cctggaggtt cttgcgcgcg gttctcggcg ggtcctcggg ccagaccgcg tccgtcagca
    14761 cgtcgacgga gaccggggtg ttgggccggg cgagcagggt ggcgaggacg atgcgctgtt
    14821 tgcggggacc gagcgggagc ggcctgccgt cccgtacggc ggtgagcggg ccgagcagcg
    14881 agaagtacac ggcgccggcc gggaccgggc gggcgggagg tcggatcatc agcgggcctc
    14941 cggaagcggg gacgaagggc agactgccgt acgtaccctt tgatgctccc taccgcacgg
    15001 tggccggcac atcggggcgg tacccgcatg ttccgccccc acacccgacc gaaaccgtcc
    15061 cgcaccccca tgttgtgggg gtgcgggacg ggggagtcag ccgttcatgc gggctcgacc
    15121 tccaccgcgc actccgccgc gaactcgcag agcgccgagc ggtccgcccg gcccgtcttg
    15181 ctgagcaggc tcgccatgtg cttctccacc gtgcgcggcg agatggagag ccgccgggcg
    15241 atctgctggt tgcccggccg ctccgggagc agcacgaaca cctcgtactc gcgcggggtc
    15301 accccgctgg tccgcagcga gagcgggatg cggtcccagc cgccccggtg ctgggtgacg
    15361 ctggccccgg cctgccgcag cgcggcccgg caggcggagg cgaccggctg cacgccgatc
    15421 ccgtagaaga actcctcggc ccggcgcagc caggcgaccg gctcgcccca cccgtcggta
    15481 cgggccgcgt ccgcgaccag gcgcagcccg agatggcggg cgaccgggaa gggggtggcc
    15541 cgggcgtcga aggaggccac caggcgggcg gccccggacc ggtcgccgtc ccggcccagc
    15601 agcacggcct cggccagctc caggaactgg ccgttccagg cgagttgggc cccgggtgag
    15661 ccgcgtacgg ccgtgaactc cgccccgtcc gccgcccccg tcagcacccg cagcaggggg
    15721 cgcagcccgt aactcccgct caggtagaag tagctggggt ggtcctgctc ccaggcgagc
    15781 accgcgtcca gcttttcgag agcgcgctcg cggtcctcct ccagcagggc gccgatcgcc
    15841 ttgcacagac ccaactggtg cggtacgagc agggattgct caccgcccgc ccgtttgaac
    15901 gcggccagcg agcggtccat gtcccgccgc cggccccggt gcgcggccat ggtggcggtg
    15961 gagagcagca gatagcggtg ggccgagtgg ttgccgaccc gggcgctggc ctccagcgaa
    16021 cggtcgatga tctcctgtgc ctcgtcccac cgggcgcaga gcaccgcgtt catggcgagc
    16081 agcccgtcca ccgtctgggt cagcagcagc gcccccagct cgaccgccgc cgcccgcgcc
    16141 gagcggagcc gggaggagtc cccggtccgc atgaaggcgt tggcgccgag ccgcaccagg
    16201 gcctccaccc gccagacggg caggtcgtgg tcggtggaga gcgcgagcat ccgctccaga
    16261 caggcgtccg ccgcgtcgaa cccgctctcg cgcagcagca gcgccagcaa ctgccaggcc
    16321 tggcaggcga ccacgggcag cccctcggcc tccgcgatct ccgccgcctc ccgggcggcc
    16381 cgctcggtct ccgaagggca ccggtgctcc tggcccggca tcagggcgag atgggcgtcg
    16441 gcgaccccga gcgcggcccg gcggccgggg gcgggctcct cgccgagcag ggcgcgggcg
    16501 gcctcgatct ggcgggccgc gtcggccgcc cgctcggcca tcacggcgac ccacgcgatc
    16561 ctgatgtgga tctcgccgcg ccggtcggcg gcctcggtcc gcgcgggcac cggcggcagc
    16621 gcgtcggcca gctccagggc cgcgtccagg tcgccgccct cggccttcgc gaccgccagc
    16681 gactcggaga tggcggcccg gtcggcgtcg gcggccaggg ggcaggctcg ctccagcagc
    16741 accacggccg aaccgtgggc ccccgaggcg agcatccgtc tcccggcctc cgcgaaccgc
    16801 agcgcggccc cggcccggtt gcccgcggcc aggtggaggg aggcgacgag ctgctgcccg
    16861 tcctcgtcca gcggctgccc ggaccgctcg acggccccgg cggcgcggcg ggcgagcgag
    16921 gcgcgctcgg ccggggcgag cgaggagatc agcgcctcgg cggtgagcga gtgacggaag
    16981 gcgtaacggt ccggggcggc cccgtccggg gcgatcaccc cggcctccac ggcggagcgc
    17041 agatgggtga agagggcccg gtcctcgaag ccggtgacgg tctggagcac ggtgaccgag
    17101 aactggccgc ccagggtggc cgccgccagt aacagctccc ggaccggctc gtccagccgg
    17161 tccagccggc gggcccagct ccggacgatc cccgagggga ccggcccgcc gggatcgtcc
    17221 gccgcctccc agccgtcctc cgactgccgc aactggtcgg tgtcgagcag gtccgccagc
    17281 agtacttcca ccaggtacgg attgccgccc gcccgttcgg ccagccgctg gtgcaccacc
    17341 tggggtatct cctcgggcgc cgcctccagg caggcgccgg tcagcacccg catctggtcg
    17401 tccccgagag gcttcaactc ccgcacgccc gccgcctgtc ggcgctcggc ggagcgtacg
    17461 agatcgagtg cggcccccgc ctccgggcgg agcgtcccca gcagcaggat cggcaggtcc
    17521 gcgaggttgt cgatgacgta ctcgacgacc gcgatcgtct ccgtgtcgct gtcgtgcagg
    17581 tcctccagca ggatcgtgca gccggactcc cggcccagca cggagagcag ccgcagcagc
    17641 gcctccgcca gctcgaccac ggtctccgga tagccgggcg aggcctcctg gcgccactcg
    17701 gggaccagcc gggccaacgc ggggtgatag ggcgccagtt cgggatcggt cggggtgccc
    17761 gccgcccgga accgggaaga gagcgcttcc acgagtggcc ggaaggggac gacgagaccg
    17821 gtcgaggtgg cccggccgcg cagcacgggc atgccgagcc cgtaggcccg gtaggcgcac
    17881 tcacccacca gccgggattt cccgatcccg gcctcgccga cgaagaacag ggcgcgcccc
    17941 gaacgccgtc gcacggcgtc cagggcgctg ctcagcaggc cgatttcctc gtcccgcccg
    18001 acgatgaccg gcgaagtggc tcgcatgggc gcaggttact ggagtcgaaa ctcatccggc
    18061 agtgccccaa tgcgccacaa tccggccgag cgtggttaaa gcggaatcat cgtggtccac
    18121 ggcaggtcga tggtgttgcc cgcctcgccc tccgaggcgc tgagaagcct gctgcgcatg
    18181 cccagcccac cgccgatacc gaaggagatc tgcccggccg ggtggtcgta gccgccgtcc
    18241 tgggggaggt tgccggatcc ctgcatcgcc gattcgctga tgtgcgtcat ctctgcctca
    18301 ttctccttgg aacggtgtgt ctctgacgtt cggtcgagta agcggtcggt cgtcggtcgt
    18361 cgggacgggc ggacggtcgg catctggtgc gtgcggtacg ggggagtggt cccggcccgg
    18421 gggccgttac gcggccccca gggacgggtt gagcagcagc gcggagccga tgcggtcggg
    18481 gaaccccgcc cgcagcagtc cgtgcccgat ccccgagagg ccggtgagca gccccgggtg
    18541 cggaacatgg ccgggggtcc cgcagcgcgg cccctcccgg tcggcggcgg ccagcagcgt
    18601 cccggcccgg cgcacccacg gagtgcggtc gccggtcagc gccgggtggc ccagcagttc
    18661 gagcaggccc agctcgccgt ggcagaggct gtcgtcggcg agcggggcgc ggtcggccag
    18721 gccaccggcg cgctccgcca gccagcccga caggtccggg tcggccaggg cggccggact
    18781 gtccgcgacc gcgagggcca ccccgacgga accctcgcac caggctccgc cgtccggcac
    18841 ctcgacggtc gcccggcgca gggcccgcag ccccgccgta cggtactgct caccgccccc
    18901 cgccgcggcg aagcgcagca gcgcccagcc gatgcccgcg gccccttcgg cgaagccgcc
    18961 ggccaccggg agcggggcca ccgcgatccg ctcggcacac cgctccgcgc cccgccaggc
    19021 ctcggcccgg ccggtcgtgc ggtggaccgt gagcagggag accagcccgc cggccgcccc
    19081 gccgcgcacc ccgtacccct gctcggcggc gcccgccgcg caggccagcc gggtggcggg
    19141 gcccgccagc tccgtcaccg tacggtcgtc gagcagggcg cccacctcgg ccagggcgta
    19201 cgcgatgccg ccgagccccg cgaaggcccc ggagcccagc accgcgaggt cgtcgacccg
    19261 gccgtgcagc gcgtccagca gccccggcac cggcgtcagc gcctcacggg ccgcctcggc
    19321 gtaccgctcg gccccggtga gggcggccag ctgcgccagg tagagggcgg gaccggtgta
    19381 gccgctcgcg aggtcggccg ccatcggggc gagccgccag taccgctcgc ccagcagttc
    19441 caggccgatc cagttggtgc ggtgctcgtg ccggtaggcg agcgagacga gctggtcgcc
    19501 caccgaccgt gcggcggaga ggaggtgttc cggctcgggg gccgtcgccg ccgtccgggc
    19561 ccgcgccccg ccctccgagc ggtgcggcgg ctcggcggag gtggagacca tcgcggcccg
    19621 gatgatccgc tcctggtcct ggcggtcgac ggagtccatg gcccggacct tcgcctcgac
    19681 ccgctccagg ccggtgggcc ccggcgtggc gggcaccccg cggccggtgc cgctccacag
    19741 ctccgcggcg ccgggccggg tgaggaagac cggcacgtca ccggcccaca gctcctcgat
    19801 ctcctcctcc tccagaccgg gcagcgcggg ggtgcccagg gtgggggtgc ggagcaggga
    19861 gaggacctgg tggcgctcgg ccgcgtcccg catcagatcg gggtgggtcg actcgtcgag
    19921 cagggtggtg taggtccagg tcggccggga gaccacccgg acctcgtccc gggcgaagtc
    19981 ggtcagcagg ccgcgcttgc ccagcagttc gtcgcggtac tcgctgacgg cggtgtagcc
    20041 gacgcggaag ccctcgcaca gggcgtcggt gtacgtggac ggatcggccg gaaccccttc
    20101 cagccggggc cggttggcgg actcggtgaa ccgcgcggaa cgccgtacca gccgcatggt
    20161 gtccaggccc gcgtcggccc agtcggcggt ttcgatgggg gagggggcgg cccggccgcc
    20221 gccgatcgcg gagacgtcga gcgcggccga gtccccgacc agcaactggg gcagcaggcc
    20281 gacccggtag gccgaggcgt gcagggcgcg ggcggcgggg tcggcggagt gcgcctgggt
    20341 gagcggcggg tggaacaggg tctccacgtc caccaggacc ggatgcggcc cgcaggcgat
    20401 caggttctcc tggtgcagat cggtgccgtc cagcagatgg agcagggcca gcagcgcgcc
    20461 ctggcgccgg tagaagagat gggtctccgc cggggaggag cagggccgct ccgccacgaa
    20521 ctccacccac ccgtactcgc cccggtccag cacccgcagt gcccgcaggg acggtgtgcc
    20581 cggcagcgaa ccgaaccatt ccaccaggga gttgaagtgc cggtgcgccg agagcgggcg
    20641 cggcttgtag accagccggg tgccgtcgtt gaagcgcagc agcatcaccg agcggccccc
    20701 gcggtggctg tcgccggccc ccgtgtcgac cccggtcagc gccccgggac ccggcccggc
    20761 gcccagcgat ccggccgtcg gaccccggtc gcccagcacc ccggaggcgg ccagcagttc
    20821 ccggtcgtcg gccagccggc cgagcatctc cgtcagggcg tcggccgcgc tcaggctcgt
    20881 ccgggccagg atgtgggcca gcacgggata ggcggtgagg aaggccgcga gcccgtcccg
    20941 tccggccgtc agccgcagga agtcccggaa ccgttccccg ggcccctcgc cggccagccg
    21001 cccggcccgc cgcgccttgt gcagctccag caccagcgtc cgcgccgcga gccgggccag
    21061 ccgcgcggtc agctgggacc ggaagtcgtc cagtacgggg gcgagcccga cggcggtccc
    21121 ggcccgtacg gcgttgttcg acggggaggt gagcagccgg gcggcggccc gctcggcgaa
    21181 cggcgccacg acgagggcga agccggtgag cccggggtac ttccgctcgg ggacggccac
    21241 cacgggcggc gcgtcggcga tgaccccctg gacgaagacc acccagtcgg gctcgcccac
    21301 gggcggctcc ccgacgactc cgcccagcca ccaggggccg ctgcgggggg agttgtcggt
    21361 ggcggccctg ggcgacgcgc cggggcggac ggtaccggcg gcacgggcgg ccccacccac
    21421 ggggtgcgca ccgccggtcc cgttcatgtg caccaccgcg gtggacccgt tcacggtgac
    21481 ggccggggga acgggacggg cagcagcccc cgtaccgccg ctgccgatca gttccttctc
    21541 caccgcacct cccaggtcgg gagcggccca ccggaccgcc tgcgaccatc ctggcggtgg
    21601 ggactccctt ggcgcatggg ggagttgccc ccatctttcg cccgtcggcg cgcagcccgg
    21661 gggttccgta cgctcccacc agggcatgtc cggcggacca ggcccgcaca gtccgcccgc
    21721 cgggcgccgc gcgtccggcc gggatccgcc gggcacgccc cggggccggg ccggtctcac
    21781 cgggtgcggt gcggcctcac cccacgcggg gcggggccgt cgacccccgg atcatcaact
    21841 cggcggcgat ggtggcgatt ccaccgggcg gcgggttctc cttgcccatc gcgagccgcc
    21901 cggcccgcgc ccccgcctcg aagagcggca gccgtacggt ggtcagcgcg ggcacggcgt
    21961 ccaccgagaa cggcaggtcg tcgaagccgg ccaccgagat gtcctgcggg atgcgcagcc
    22021 cctggtcccg tacggcggcg caggcgccca gcgcgacggt gtcgttggcg gcgacgacgg
    22081 cggtgatgcc gggctcccgg cgcagtatgt cgagggtggc ctcgtagccg gagcgccggt
    22141 cgtaggggcc gtgcacggtg agccgcccgc cgtccacgcc ctcgccgtcc ccgccgtcca
    22201 gccccgcgcc ccgcagcgcc tcgcggtggc cctccagccg gtggcgggtg gtggtgcgtt
    22261 cggggggccc ggcgacgtat ccgatgctgc ggtggcccag cgagatcagg tgctcggtca
    22321 gccgccgccc gccgccccgg ttgtcgaagg cgagcgcggc gacgagcgcg tccccctcgg
    22381 ggagcggggg gcgcccgcag aagacgatcc gggtgcccgc gtccgccagc ttggccagct
    22441 tcgcggccat ggcggtctgg tgctcggggt cctcgatcgc gccgccggtg aggacgacgg
    22501 cggcggcccg ctggcgctgg aggagggtga gataggtcag ctcgcgctcg ggggagccgc
    22561 cggtgttgca gatgacggcc agcttctcgc cgcccgcccg cccggtgccg tccccgggcc
    22621 cgccgatctg ggtctgcgcg gccccggcca tgatcccgaa gaaggggtcc gcgatgtcgt
    22681 tgaccaggat gccgacgagg tcggaggtgg cggcggccag cgagctggcg ggcccgttga
    22741 gcacgtagtc gaggtcgtcg accgcgcgca ggacccgctc ccgggtcgag gcggcgaccg
    22801 ggtagttgcc gttcagcaca cgggagacgg tggccgggga cacccgggcg cgggccgcca
    22861 cgtccgccag ggtgactgtc atcgctttcc tccgtgaggt cacgtgcggc gcccctcttg
    22921 tccggccgct gtccgcaggc tagcgtcatc tcgtatagaa agcgcttgct acggctgtat
    22981 ggagggaact tcgtgacacg caggacagtg cgcatcgcca tgaacggcgt cacgggtcgc
    23041 atgggatacc ggcagcatct ggtgcgttcg atcctcgcga tccgcgagca gggcggcctg
    23101 gacctcggcg gcggggaggt cctctggccg gagcccgtcc tcgtcggccg ccgcgcccac
    23161 gccctggagg agatggctgc gctccacggt ctgaccgagt ggtccacgga cctggacgcg
    23221 gtgctcgcgg acgacacggt ggagatctac ttcgacgccc aggtcacctc ggcccgggtg
    23281 gagtcggtca agagggccgt ggcggccggc aagcacatct atacggagaa gcccacggcg
    23341 acggacgtcg agggcgccct cgacctggcc cggctggcgc gcgaggcggg catcaagcac
    23401 ggcgtcgtcc aggacaagat cttcctgccg ggcctgctca agctgaagcg cctgatcgac
    23461 ggcggcttct tcggtgagat cctctccatc cgcggggagt tcggctactg ggtcttcgag
    23521 ggcgactggc aggaggccca gcgcccctcg tggaactacc gggcggagga cggcggaggc
    23581 atcgtcgtcg acatgttccc gcactgggag tatgtgctcc acgagctgtt cggccgggtg
    23641 acctccgtga cggcccaggt gcacacgcac gttccgcgcc gctgggacga gcacggcgag
    23701 ccgtacgagg cgaccgccga cgacgccgcg tacgggatct tccagctggc gggcggggcg
    23761 gtcgcgcaga tcaactcctc ctgggcggtg cgggtcaacc gggacgagct ggtggagttc
    23821 caggtggacg gcacccacgg ctccgccgtc gccgggctgc gcaactgccg cgtacagcac
    23881 cgctcttcga cccccaagcc ggtctggaac cccgacctgc cggtcaccga gccgttccgc
    23941 gaccagtggc aggagatccc ggacaaccag gagttcgaca acggcttcaa ggcgcagtgg
    24001 gagctgttcc tgcgccatgt ggtgctcgac gagccgtaca cctgggacct gctcgccggg
    24061 gcgcggggcg tccaactcgc cgaactgggc ctgaagtcgt cggcggaggg ccgccgcctc
    24121 gacgtcccgg agctgaccct gtgacggcat cggcatcggc atcggcaccg gtaccgctgc
    24181 cgcagggccc gtacaccccg cgtgccaccc cgctggagct gcccgccggg ggtgcgccgc
    24241 tcacctcccg tacggtctac tcggcggccc atgtggtcgc ggacccgtac gcggacaccg
    24301 gaccggacgg cccggcggcc gtcgactggg agtccacgct cgccttccgc cgccacctct
    24361 ggtcgcacgg tctgggcgtg gcggaggcga tggacacggc ccagcggggg atgggcctgg
    24421 actggccggg cgcggcggag ctgatccgcc gctcggcggc ggaggcgcgg gcggtgggcg
    24481 gccggatcgc ctgcggagtg ggcacggacc aactcctcct gacgtccgaa cccaccctgg
    24541 cggaggtgac gtcggcgtac gaggagcaac tggccctggc cgaggcgaac ggcgtacagc
    24601 cgatcctgat ggcgtcgcgc gccctgaccc gcgcggcaag gggccccgag gactacctcg
    24661 cgacctacgc ccacctcctg cgccagtcgg gggagccggt gatcctgcac tggctgggcc
    24721 cgatgttcga cccggcgctg gagggctact gggggagcgc ggacctggac gaggcgaccg
    24781 acacgttcct gaaggtgatc gccgaacact cggacaaggt ggacggcgtc aagatctccc
    24841 tgctggacgc ggcccgcgag atcgacgtac gccgccgcct gccgtccggc gtgcgctgct
    24901 acacgggcga cgacttccac taccccgagc tgatcgcggg cgacgaacag ggcttcagtc
    24961 acgccctgtt gggcatcttc gacccgctcg gccccctggc ggcacacgcg gtacgcgtac
    25021 tcgacacggg tgacgtggac ggcttccggg ccctcctcga ccccacggtc gaactctccc
    25081 gccacctctt ccggccgccg acccgcttct acaagacggg cgttgtcctg ctggcctggc
    25141 tggcgggcca ccaggaccac ttcacgatgg tgggcggcct ccagtcggca cgctcgctgc
    25201 cgcatctggc gagggcatac caactggcgg acgggttggg cctgttcccg gacccggagc
    25261 tggcggcgca ccggatgcgg gccctgctgg aggtacaggg aggaacaaga tgacaacagc
    25321 acagaccccc gctcccatct ccgcccccac cgcctccctc gcgcgtctct cgatcaacca
    25381 ggagacgatc aagcagtggt cgctgcccga gctggcggag gggtgcgtca aggcggggat
    25441 cggccaggtc ggcctgtggc gggcgccgat ccaggcgtac ggcgtcgagc gcacggcgag
    25501 gctcctctcc gacgccggcc tcacggtcac cagcctctgc cggggcggct tcctcaccgc
    25561 cctggacccg gccgcgcggg ccctcgccct ggacgacaac cgccgtgcgg tggacgaggc
    25621 ggcggccgtc gccacggaca ccctggtcct ggtctcgggc ggcctcccgc ccggcagccg
    25681 cgacctgtac ggcgcccggg agcgggtggc cgaggcgctg gccgaactcg ccccgtacgc
    25741 ggcggagcgg ggcgtacgtc tggcgatcga gccgctgcac cccatgttcg cgtccgaccg
    25801 ctgcgtggtc tccaccctgg cccaggccct ggacctcgcg gagcgcttcc cggccgagcg
    25861 ggtcggcgtg gtcgtcgaca cgtaccacct ctggtgggac gaccgggccc ccgccgagat
    25921 cgcccgggcc ggggcgggcg gccgtatcca cgccttccag ctggccgact ggatcacccc
    25981 gctcccggcg ggcgtcctgc tgggccgggg ccaactgggc gacggcagcg tggacttccg
    26041 cgcgttccgt gcggcggtgg aggctgcggg ctacgacggc ccgatcgagg tggagatctt
    26101 caacgaggag ctgtgggcca gggacggggc ggaggtgctg gcggaggtgg cggcccgcta
    26161 cggacaacat gcctgctgag agccctgacc ggaccccgag gtaaagagat cgtcaagggc
    26221 tgcaaccttc gtgtgccctc ccgggtcaca catggcgtcg ggacttccgg ggaggggtcc
    26281 ggggggaacg ggaaggcccg acagggggaa agcgaggggg gtccggccgt gaggccggac
    26341 cccgttctcg cgtgcggccc ggggcggccg caccggtcac tcgaagaact tcaggctgtg
    26401 gcccacgtcg gtggggctgc cgggaacgtt ggcgcgccgg taggtggtgc tgccccacca
    26461 gaccgccgtc ccggagtacc agtggcggtt ggaccaggtg tacggggtgc ccttggcgac
    26521 cgcgtggtac agcgtgggga agcggttgcc cgacgggggg ccctcgttga cgtcgccctg
    26581 cggcaggacg aacgtctggt ggccggggcc gtccacgttc accgtcggag tccagccgga
    26641 catcatggac ggcgcgtgcg agccgaagag gcagccgttg ctcttgtacc agtcccagac
    26701 gtaggtggga tcgccgcccg ccctgagcct caggtcggcg atgcagtact tgttgctcca
    26761 gctcccgttg gcggagtaga cgacgtgcag ccggccctgc gggtcgacga tgggctgggg
    26821 ggcctcgttg atgtacgggt tgccgacgac ccgctcccac ggctcgcgcg gctgcgagat
    26881 gacgtaccgg ccgccggtgg ccgcggtggg gctgctcatc cgggcgatgt agaggttctg
    26941 ctcgacgttg gtgtcgccgg accagcccga ccagacgaac cagcgctggc cgttgaaggt
    27001 gaaggggacc ccgtcgatcg cccacttgtc ggcgggcagg gacaccttga cggccgcgga
    27061 gtagccggac gtcggggtgg cggagccgat gtggtacatc cggtgggccg caccccgccc
    27121 ggcggcgaag tagatgcggt actgacccgc gtggtgcacg atctccgggg cccacacctc
    27181 gcccaggttc ccggtgtcgc gccacacctg gtgcttgggg gccgtggcca cgccttccgc
    27241 cgtggacgcc gtccggaccg cgatgccgcc gtccaccgcc ttggcggaga cgtagaggct
    27301 gccgaccttg atgacggtcg gatcggcgcc gcccaccagc gagcggccga gcgccgagaa
    27361 gtccccggcg gctcccgggg cggtggacgc gggccggtcg gtggacgcgg gccggtcggt
    27421 ggcgcgttgc acgggctggg cggccgtcgc ggtctgcccc agtgcgagca gggcggccag
    27481 tcccagcgtg acggctccgg cgagccggcg ggaagggggc atgggggtcc tcctggcggg
    27541 tgcgcggcga cgcgggtgcg agcgcctgag cgcgggtgcg agagcctgac tgagagcgct
    27601 ctcaacgttc gcgggtggcg tacggacctg tcaagggccc ggcggtcggg tgggaggctg
    27661 tgggcctgca ggcctatcag ggcccaaatc ccttccgtat gaaccctgtt gacctgcggt
    27721 gacggcggtg gggcccgggc tgtgcccttg acggcgggca ggcggggcgg ttcgctgacg
    27781 cccagccacc ccccacttcc cgcgattcgc cggaggacag cccgatgccc ccgacacccc
    27841 gccccgtctc cttcggcccc gtccggccgg cgctctgcgc ggccgtcgcc ctgatgctcg
    27901 gtgtgctccc ggccgcgacg gcccgggccg ccggacctgc cgcgcctccg ccctccgtcg
    27961 ctccttcgac ggcggccgcg cctccgcctt ccgcagctct ttcgacggtg gccgcacctc
    28021 cggcctccgc cgtggctccg ccctccgccg cgcctcaggt ccccctcccg cccgaccgga
    28081 gcgagcggtc cggacgggcg gagccgggcg gcgagccgtc acggccgact gtcgccgccg
    28141 acggttccgc cgtctcggcg gcactctgca acaagcactg cgacgcccgc gaccccgcgg
    28201 ccgcgacctc cgaccgcgtc ccggtcaccg cctccctcca cggccgctcc atcgccctcc
    28261 atctgtccga caacgatgtc atgggctggg cctccatcga caacggtcag gcgggcgacc
    28321 agacctggct cgaccgctcc ttcgacggcg gccgcacctg ggcctcgggc agcaggctcg
    28381 gggccacggc gatccccgcg ggccggaccg gctggcgctc ccagatgtac aacgtggacg
    28441 actggaacag cggcggcatc ggggccctgc gcgcctgcgg aaaggccggc gaccgggcgg
    28501 agatcgcctg caccggctgg gcgcgcgtcg actggaacgc cgggagccgg agcaaggccg
    28561 cggcgacggc cctgatgatg aactacgacc gcgcttccgg gaagttcgcc ggctggtgga
    28621 cctcggccac cgcgctcacc tcgctgatcg acaacatccg gatcagccac atgccgagct
    28681 accgctacgc cgtcgccaac acctacgaca agctgcgcac ggccgagggc ggcgacttca
    28741 ccaactccta tctggacgac accggatggt ggggcctcgc ctgggtcgcc gcgtacgacc
    28801 tgaccggcga ccgccgctac ctggacaccg cgcgcaagga cgccgaccac atggcggcct
    28861 actggacgga caagtgcggc ggcggggtgc agtgggccac ggacaaggcc tacaagaacg
    28921 ccatcaccaa cgagctgtac atccagctca acgccgcgct ccacaaccgc ctcccgggtg
    28981 acaccaccta tctgcggcgg gcgacgaccg gctgggactg gttcaggaac agcgggatga
    29041 tcaactccgg caacaccgtc aacgacggcc tgcgggacga ctgcaccaac aacggcgaca
    29101 ccacctggac gtacaaccag ggggtcatcc tggcggccct cgccgagctg caccgggcca
    29161 ccggcgacgc ctcgctcctc gcccgggccc gcaccctggc cgacgcctcc acgacctccg
    29221 cctacctcaa ccccggcggc accctccacg agccgtacga gccggacggc acgggatgca
    29281 cctccgacgg cgactccttc aagggcgcgt acgtcagggg cctcggcctg ctcaacaagg
    29341 cgctcccgga ccgcccgtac agcgcctacc tggaccggca ggccgacacc gcgtacgcga
    29401 agaaccgcaa cagcctggac cagtacggcc cccactgggc gggcccgcgc acggtcaccg
    29461 gcaacggctg ccagcacagc gccctggacc tcatgaacgc ggcggaggac agctgacctc
    29521 tcccgcacct tcttcccgcc ccgctgtccc gccccacgcc gtcctcccgc cccgacgccg
    29581 tcccgcctct gcctgctcca ccccaccccg accgccgtcc tacctccggc tgacccaccc
    29641 cggcccgcgc gggggcggcc cccgacagct ctccaccaca gccccgaagg agtcccatgc
    29701 cccggtccgc acaccggccg acccggcgag ggcgcgtgct gcgccgaggc ctcaccgtca
    29761 cgctgacggc cgccgccctc gtcctcacca ccgccaccat ggcccacgcc gccccgccgc
    29821 cgcccctgcc cggcaacgcc gacgacctgg aacggaggtt ccagccggct ctcgactacg
    29881 acaaggacgg ctgctacgcc acctccgcga tcggcccgga cggcacgatc gcgcccggac
    29941 tgaagctcgg cggcgccctg aacggcgact gccgcgacct ctcggacctg gagaacagca
    30001 acgcctactc ccgggcgaag tgcgacaacg gctggtgcgc catcctctac acctactact
    30061 tcgagaagga ccaggtggcg ccgggcggcc tgttcggcgg ccaccgccac gactgggagc
    30121 acgtcgtggt ctgggtccac gacgacaagg cccagtacgt ggcgacatcg gcccatggca
    30181 acttcgcggt ccacaaggcc gcggacgtcc ccttcgacgg cacgcacccc aaggtcgtct
    30241 accacaagga cggcgcgagc acccactgct tccgcaaggc caccgccaag gacgagcccc
    30301 cggagaacca ctacggcacc tggcactacg caccactggt cggctggaac ggctacccgg
    30361 acggcctgcg cgacaagctc ctcgccgccg acttcggcaa ggcgacgatc ggcatccggg
    30421 aggaccgttt caccggccac ctgaccaagg ccctccccaa gggggtgccg ttcaaccccg
    30481 cgagctgaac ggggcggggc gtgctccttc cctcgtacgg cctccgcccc gggggcccgg
    30541 acgaaggagc acgcccccgc ccccggggac aagagaacga tcgcgaagga actgctccca
    30601 ccctccggga cccaccgcac cggaccaggc cccggcctgc ccgccgggga cccacactct
    30661 gtccccggac tggatcggac cacccccgct cgcgcgggga gcacccgggc ggcgaaggcg
    30721 cgttcatcct gtgctccgga acacccccgc tcgcgcgggg agcacgggga gtacggggcc
    30781 gtcatccgct ccctctccaa cgcgagagca gatgagtacc ccggacccgg gagcgcatcg
    30841 gcggaaggcg cggcgacgac ggccgaccag agccgtcctt cacgaggacc gccgcctcac
    30901 gcagatacag cgcggcgagc cgaccgggat ggaccgcaag accgtccacc gtatcgagta
    30961 cggcaccagc gccccgagcc tgaccacgcc gctccgcctg gcggcggcgc gcggcgtacc
    31021 gctcgccgag ctcgtcgccc gggccggcag ccgtcgcgga gccgggcggc tacgcctcag
    31081 gcttggtggg aatcaggaac ccccgtactg ggcggggctc gtccgggtca cgcgagtccg
    31141 gctcctgccc cgccttccac gcggccacca ggtccgcata ccgcgggtcg gtccattcct
    31201 tcgccatgag gcacctcctc cccggaaggc tacggccact ccggcttcgg catgggccgg
    31261 atcgtgcact ccggggcgtg ctggcaccgt gcggccaccg ccacgagggt ctcgtcggac
    31321 ggctcgcccc acagcttcgc gtccggcacg taccccaggc tggtgatggc ctgccgggtg
    31381 cggtccaaga tggccgggtc gtagtgcgtc gggtcgtacc cggggaagtg cgcggcaacg
    31441 tcagccggca ggctcgaact caacggtctc ctggccgcag ctctcagcca gtacggccaa
    31501 ggttccgccg ccgcctgatc gaccgacagc cccccgcgga gtt
//
