LOCUS       NC_019673              22886 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Saccharothrix espanaensis DSM 44229, complete sequence.
ACCESSION   NC_019673
VERSION     NC_019673.1
KEYWORDS    RefSeq; complete genome.
SOURCE      Saccharothrix espanaensis DSM 44229
  ORGANISM  Saccharothrix espanaensis DSM 44229
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Saccharothrix.
REFERENCE   1
  AUTHORS   Strobel,T., Al-Dilaimi,A., Blom,J., Gessner,A., Kalinowski,J.,
            Luzhetska,M., Puhler,A., Szczepanowski,R., Bechthold,A. and
            Ruckert,C.
  TITLE     Complete genome sequence of Saccharothrix espanaensis DSM 44229(T)
            and comparison to the other completely sequenced Pseudonocardiaceae
  JOURNAL   BMC Genomics 13, 465 (2012)
   PUBMED   22958348
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9360653)
  AUTHORS   Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2012) IGS, CeBiTec, Bielefeld University,
            Universitaetsstr. 27, D-33335, GERMANY
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000328705.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:06:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,523
            CDSs (total)                      :: 8,451
            Genes (coding)                    :: 8,313
            CDSs (with protein)               :: 8,313
            Genes (RNA)                       :: 72
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 43 of 138
            Pseudo Genes (incomplete)         :: 116 of 138
            Pseudo Genes (internal stop)      :: 7 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:45:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7144343
            Orig. end                         :: 7167229
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            HE804045.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22886
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="34"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22886
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22886
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12886](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12886
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(749..764)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.52"
                     /tool="antismash"
     misc_feature    1623..1637
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.13"
                     /tool="antismash"
     misc_feature    complement(1624..1637)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.56"
                     /tool="antismash"
     misc_feature    complement(1631..1646)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.95"
                     /tool="antismash"
     gene            1675..2220
                     /locus_tag="BN6_RS30845"
                     /old_locus_tag="BN6_64060"
     CDS             1675..2220
                     /EC_number="3.4.24.-"
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103760.1"
                     /locus_tag="BN6_RS30845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64060"
                     /product="snapalysin family zinc-dependent metalloprotease"
                     /protein_id="WP_015103760.1"
                     /transl_table=11
                     /translation="MTGKLLRLALGALFTSLALVGTSLTTAATAAPAAPSALARTVYYS
                     ASGYSAEADQAAQIWNSRVPNLRLVRGGSATIRIAATNGGGSRAYPCGLGCATIYIDNR
                     DVAAGNYALRIVAHEIGHGLGLPDTYNGICSYLMSGGSAGTSCRNVYPNAQEANRVNQL
                     FAGRAVAAVGNPEVYARG"
     gene            complement(2514..3467)
                     /locus_tag="BN6_RS30850"
                     /old_locus_tag="BN6_64070"
     CDS             complement(2514..3467)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103761.1"
                     /locus_tag="BN6_RS30850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64070"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_015103761.1"
                     /transl_table=11
                     /translation="MSAGKITGIVAAAALALAACAGADGAVTEDKVVAGGKTVNLSPQQ
                     DRITATKVDAIAAKVPESVRQTGKLVVGGSSTTAPPLRFYASDDKTIIGVETDIAVLIA
                     GVLGLEPRLEVTSWENLFVGLDSGAYPLGLSNITVTEARKEKYDFATYRLDTLAFEGRK
                     GDSWRVTRPEDVAGRTIAVGSGTNQEKILVEWSRKNEAAGLKPTDIKYFQNASDYYLAL
                     ESGRIEAYLGPNPVSAYHAVTSGKTEVIGTISGGGELPGKIAATTKKGSGLVEPVAEAL
                     DHLIENGKYGEVLARWGLENEAVTASEVNPPGLPKS"
     gene            complement(3479..4231)
                     /locus_tag="BN6_RS30855"
                     /old_locus_tag="BN6_64080"
     CDS             complement(3479..4231)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020642395.1"
                     /locus_tag="BN6_RS30855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64080"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_148303449.1"
                     /transl_table=11
                     /translation="MVDLRGIHKSFGANEVLRGVDLEVRAGEVVVVLGPSGSGKSTLLR
                     TINHLEKVDRGHVSIDGDLVGYRRVGDKLHELREREILKQRTHIGFVFQNFNLFPHLTV
                     LENVVEAPVSAQRRPVAEVRTRARALLARVGLADKEDAYPRHLSGGQQQRVAIARALAL
                     EPKVLLFDEPTSALDPELVGEVLDVIKDLARSGTTMVVVTHEVGFAREVADTVVFLDGG
                     VVVEQGPPGQVLDDPQQPRTRAFLSKVL"
     gene            complement(4231..5130)
                     /locus_tag="BN6_RS30860"
                     /old_locus_tag="BN6_64090"
     CDS             complement(4231..5130)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103763.1"
                     /locus_tag="BN6_RS30860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64090"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_015103763.1"
                     /transl_table=11
                     /translation="MSVSAQPRLRAPDDDLSRLKVVPARHPWRWVGVVVVLVLLAQFVN
                     GLVTNPGWDWPTFARYFTAESILRAVGVTLELTLHGTAIGFALGIVLALMRLSHSRFLA
                     GVSWTYIWAFRSIPLIVQVLFWFNISYLYQELEFGIPFGPTFFGVDTKDLISPMGAAVL
                     GLGLHQAAYAAEIVRSGIISVDHGQLEAAAALGIPKSRQFRRIVLPQAMRSILPNAANE
                     VISLFKGTSIVSVVAIGELFYQVQVVYGRNARVVALLMVATVWYVVLTTLLSVVQHYVE
                     KRYAKGSTRDKGGWKWAR"
     CDS             5196..5417
                     /gene="allorf_7149539_7149760"
                     /locus_tag="allorf_7149539_7149760"
                     /protein_id="allorf_7149539_7149760"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MWGQRVWGGERRSAAATDRAGDPAVVDVPAGAEDGHSRSPSRLVL
                     TIRCTEPVSHDWTRSCHFARSRTRVPTC"
     CDS_motif       5196..5243
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MWGQRVWGGERRSAAA"
                     /locus_tag="allorf_7149539_7149760_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       5244..5417
                     /prepeptide="core"
                     /locus_tag="allorf_7149539_7149760_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="6014.6"
                     /monoisotopic_mass="6011.0"
                     /core_sequence="TDRAGDPAVVDVPAGAEDGHSRSPSRLVLTIRCTEPVSHDWTR
                     SCHFARSRTRVPTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MWGQRVWGGERRSAAA"
                     /leader_location="[5195:5243](+)"
                     /alternative_weights="6032.6"
                     /alternative_weights="6050.7"
                     /alternative_weights="6068.7"
                     /alternative_weights="6086.7"
                     /alternative_weights="6104.7"
                     /alternative_weights="6122.7"
                     /alternative_weights="6140.8"
                     /alternative_weights="6158.8"
                     /alternative_weights="6176.8"
     CDS             complement(5232..5303)
                     /gene="allorf_7149575_7149646"
                     /locus_tag="allorf_7149575_7149646"
                     /protein_id="allorf_7149575_7149646"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAVLCSRRHVDYGRVSSAICRRG"
     CDS_motif       complement(5265..5303)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAVLCSRRHVDYG"
                     /locus_tag="allorf_7149575_7149646_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(5232..5264)
                     /prepeptide="core"
                     /locus_tag="allorf_7149575_7149646_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="1068.2"
                     /monoisotopic_mass="1067.6"
                     /core_sequence="RVSSAICRRG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAVLCSRRHVDYG"
                     /leader_location="[5264:5303](-)"
                     /alternative_weights="1086.3"
     CDS             complement(5355..5552)
                     /gene="allorf_7149698_7149895"
                     /locus_tag="allorf_7149698_7149895"
                     /protein_id="allorf_7149698_7149895"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPPRAEVRVRWRAQPAYGPVSPPVHARHWSIRVMRGLVNRRHIVV
                     SAGGHSCSRAGEVATSRPVV"
     CDS_motif       complement(5406..5552)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MPPRAEVRVRWRAQPAYGPVSPPVHARHWSIRVMRGLVNRRHIVVSAGG"
                     /locus_tag="allorf_7149698_7149895_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(5355..5405)
                     /prepeptide="core"
                     /locus_tag="allorf_7149698_7149895_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.20"
                     /molecular_weight="1583.8"
                     /monoisotopic_mass="1582.8"
                     /core_sequence="HSCSRAGEVATSRPVV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPPRAEVRVRWRAQPAYGPVSPPVHARHWSIRVMRGLVNRR
                     HIVVSAGG"
                     /leader_location="[5405:5552](-)"
                     /alternative_weights="1601.8"
                     /alternative_weights="1619.8"
                     /alternative_weights="1637.8"
     misc_feature    5394..5407
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.19"
                     /tool="antismash"
     misc_feature    complement(5555..5571)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.41"
                     /tool="antismash"
     gene            complement(5841..6029)
                     /locus_tag="BN6_RS30865"
                     /old_locus_tag="BN6_64100"
     CDS             complement(5841..6029)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN6_RS30865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BN6_64100"
                     /product="hypothetical protein"
                     /protein_id="WP_015103764.1"
                     /transl_table=11
                     /translation="MHLDWTALGQVFLVSFALGAGTVALFSAGLAATSRGNRVVPAACF
                     LVCAAVAGYGIYLVAVH"
     gene            complement(6041..7129)
                     /locus_tag="BN6_RS30870"
                     /old_locus_tag="BN6_64110"
     CDS             complement(6041..7129)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103765.1"
                     /locus_tag="BN6_RS30870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64110"
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_015103765.1"
                     /transl_table=11
                     /translation="MDVVVVVVVLTALAFDFTNGFHDTANAMATSIATGALSPRVAVAV
                     SAVLNLVGAFLSIEVARTISSGLVDEARIGPAIVFGGLVGAVVWNLATWLLGLPSSSSH
                     ALFGGLIGATWVAAGADAVRFAAVVEKVLVPAVASPVIAAVVAGTATFLAYRITRRAKA
                     ATRGFRYGQIASASLVSLAHGTNDAQKTMGVITLTLITAGALPAGAEPPLWVIVSAGTA
                     IALGTWLGGWRIIRTLGKGITDIEPPQGFAAETAAATVILTSSQLGFALSTTHVCAGGV
                     VGAGVGKRLADVRWTVAGRMAVAWLLTLPAAALVGALAGETAARGPVGVLAVAVAGVVV
                     AAVCWTLSRRDPVGAHNVNHAA"
     gene            complement(7278..8342)
                     /locus_tag="BN6_RS30875"
                     /old_locus_tag="BN6_64120"
     CDS             complement(7278..8342)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Catalyzes the reduction of N-ethylmaleimide
                     (NEM) to N- ethylsuccinimide"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103766.1"
                     /locus_tag="BN6_RS30875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64120"
                     /product="alkene reductase"
                     /protein_id="WP_015103766.1"
                     /transl_table=11
                     /translation="MTTAFDPLDLAGTRLPNRVVMAPMTRSRAYGTTPTQATAEYYAQR
                     ASAGLIITEGIQPSPVGQGYPDTPGLHSAGQVEAWRGVTDAVHAAGGRIFAQLMHTGRI
                     GHPSLLAGDLHPVGASPVRAAGQVFTGTSMADFVTPVELSHADIEATVADFAAAARNAV
                     AAGFDGVELHGANGYLIHQFLAPNTNLRTDGWGGSVAGRTRFAVAVVEAVADAIGAHRL
                     GLRISPANTYNDIAEHDHRELYPALVDAIDPVGLAYLHVLESDRESTRELRERSRSALI
                     LNPHTPGGVTGPAELGLVADGTADAVAFGALFLANPDLPERLASGGPFNTPDTSTFYGG
                     DERGYTDYPALATV"
     misc_feature    8454..8474
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
     misc_feature    complement(8461..8476)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    8490..8503
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.31"
                     /tool="antismash"
     gene            8503..9057
                     /locus_tag="BN6_RS30880"
                     /old_locus_tag="BN6_64130"
     CDS             8503..9057
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020628630.1"
                     /locus_tag="BN6_RS30880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64130"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_084672812.1"
                     /transl_table=11
                     /translation="MAGQAAKPTSVPVPSTAVYGPISHAIFRIARLHRMLAGQLLREAG
                     LHPGQELVMMHLWDSGPRRQAELVDVLDSDSATMTRTVQRLERAGFVRRTPDPTDRRAT
                     LVEATAASQALRHQVCRIWQELEEATTAGCPDVKRGEFLRTLEQLECNLVTRTGRSPLP
                     QSAATTGSGRAAGHSTVTDTR"
     gene            9127..9684
                     /locus_tag="BN6_RS42625"
                     /old_locus_tag="BN6_64140"
     CDS             9127..9684
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN6_RS42625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BN6_64140"
                     /product="hypothetical protein"
                     /protein_id="WP_015103768.1"
                     /transl_table=11
                     /translation="MPVQRWVFAVLALALATAGCSTPVAGKPVAGPVTVEGAAPEVVRW
                     MNNFCGVANYMVASGGVKFDQPPADPVAAKKAISDALGRVVDVLNVAVHDLEELTPAPV
                     TAADAAVEVIVEPLSKARDKFVSAKSTVDGAAELTTDVFSAVMQNMTEAVSVMNEAVEK
                     MSVVKLPDTFTTAAEQAENCKK"
     gene            complement(9688..9852)
                     /locus_tag="BN6_RS47075"
                     /old_locus_tag="BN6_64150"
     CDS             complement(9688..9852)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN6_RS47075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BN6_64150"
                     /product="hypothetical protein"
                     /protein_id="WP_015103769.1"
                     /transl_table=11
                     /translation="MTVPGRLEGTAESEAVGERAPVTPTLPFKSALMDRAGARTRFQAD
                     ARAVRRGRL"
     gene            10001..12886
                     /locus_tag="BN6_RS30890"
                     /old_locus_tag="BN6_64160"
     CDS             10001..12886
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103770.1"
                     /locus_tag="BN6_RS30890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64160"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_015103770.1"
                     /sec_met_domain="DUF4135 (E-value: 1.2e-103, bitscore:
                     346.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.3e-31, bitscore:
                     106.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPSAVDRLPASWWHRGVRGGSHELVAPRGRPAWAAFVERATATA
                     AHATFPGGDWDEAFAFALRPLVDAARAQDARLDDDFGRRLGLRLARLAARALVLELNLE
                     RLAHRLVGETPQERFAHFVQHLDLADLVAKYPVLARLLGQACLHAVAAHRELLDRFAAD
                     RGTIVRTLLDGRDPGRVAQVETGRGDAHQHGRSVAVLTFEDGRRVVYKPRPVALHARFG
                     ELVAWFDGHTRLGLRVPRAVARETHGWLEFVDQAPCADVTEVGRFYHRLGALIALLYAV
                     DGTDMHYENLIAAGDQPVLVDVETLFHPTVGIPADPAVRALARSVHRTAVLPRVLLGEH
                     GALDIGGMGGDHGELFPADGVAWLNPGTDRMRLVRRPAPMPPARNRPSVAGVEAEPADY
                     QGALLAGFRTGYDALFDHRAELLGDDGLLAGFADLPVRFVPRMTQLYATLLDESTHPDA
                     LRGAPDRDLALDVLWDESAEDALRALVPHELTDLWAGDVPLFTTRPGSRDVWSAGGERL
                     PDLLPESGLEAVARKVAALDEVDRHDQQWLISAALASRPRPVDHRSGAGVPAPLEAGIP
                     DPQRLLVAACGIADEVLARASTDGGRVNWVGLELVDDRHWAVAAMGAGLSNGYPGVALF
                     LAQLGALTGAGRYTAFAREAIAPVPGLLRSFAADTELAVAVGSGAFHGLGGICYALARL
                     STLLQDDEITGWLAEAVAVAEQVEAVGEDPANIVEGWAGGLAAMLAVHAETGLPAAERL
                     ARRYAARLIAANPGGDGFARGRAGVGWAMLRYARHARDQRHGVAGRANLRADHALRQRL
                     LDVGEADHSWCSGLSGAVLAHAAHPDQPVDTYTLHLDRCLNALAVHEPLRDLSLCHGEL
                     GVLESLAVLAERGHDLATAMLTRRAGLVLGAIDQYGARCATPGGVPSAGLLTGLSGIGY
                     GLLRLGFPERAPSVLLLETPANPYPRKENPR"
     gene            12883..13092
                     /locus_tag="BN6_RS30895"
                     /old_locus_tag="BN6_64170"
     CDS             12883..13092
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN6_RS30895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BN6_64170"
                     /product="hypothetical protein"
                     /protein_id="WP_015103771.1"
                     /transl_table=11
                     /translation="MSNANHDEVTTWDDGQDGDHPAGEMALSRKSKTGARARALAGLTL
                     AVGAYVVVAAGLADSTSVSAPVTY"
     gene            13198..15246
                     /locus_tag="BN6_RS30900"
                     /old_locus_tag="BN6_64180"
     CDS             13198..15246
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.5"
                     /locus_tag="BN6_RS30900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64180"
                     /product="AAA family ATPase"
                     /protein_id="WP_015103772.1"
                     /transl_table=11
                     /translation="MQTRAPVVVGRDDELRVLARTLTDAAACRGRAVFLVGEAGIGKTR
                     LARVAAGAAFDRGMRVLRGRGSTIGPMVPFRPLAEALMSLLRGGDAPDLRELGPYQPVL
                     GRLVPEWGGEPQAGHSIVVLAEAVLRLLAVVGRVRPCLLVLEDLHDSDAETLAVIDYLV
                     DNLDQVPAALLVTARADPGPTLDVVRLAAQRDAGSLLELRPLREGEVRRMVASCLEVDE
                     AEVPEAVAQRLWSDSAGNPFVVEEMLHGLVSGGLLVRGPAGWQVLGELRINVPTALVRS
                     IAHRTDRLGPQGRELLSVAAVLGHRFPLSVLRAVTGMDDHSLLTHLHAGVAAQLVTPDE
                     PVPDWYAFRHPLTAEALLAQLTPTHRADVSRRTADAVVELHPGLPGEWCPLVASLRLDA
                     GQNAEAGALLAEAGRRALADGAAGSAVRLLDHAHRLPLGRVDVGLRADVLASLLPALGE
                     AGQFERAFALQDAVAELSAAGLDRVRRAELHTGLAKVAWLAGREEDGMAQVEAARSLLG
                     PDADDAHSARLDSVEKFLTLDARLPDRIAKRSCWPAGRPRRPAGRRCPRWAARRGSCSA
                     SWPGNGTWARPPTTSPGPAGSPRSTGCRSSGSTPWCGWPGWTGWPTARRRSWSRRARRR
                     CGSARSRWPTTSTRSSGWTSCCAGSTRRRASSWPAAARGPAGCNSSR"
     gene            15957..16118
                     /locus_tag="BN6_RS49240"
     CDS             15957..16118
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="BN6_RS49240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_231905449.1"
                     /transl_table=11
                     /translation="MAGRLGNKAIATRLHISPRTVEKHVASLITKTAQPDRESLSAFAA
                     DLGPSDRP"
     gene            16180..16881
                     /locus_tag="BN6_RS30905"
                     /old_locus_tag="BN6_64200"
     CDS             16180..16881
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088109.1"
                     /locus_tag="BN6_RS30905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64200"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_041318715.1"
                     /transl_table=11
                     /translation="MVVMGGVVGVGGVAQASEEPYRDPDVTRGPCAYTKTPDDPAARPV
                     KLPPDPRRTPDRGRVEVLLKTNQGDIPLVLDRAQAPCTVQSFLHLVEKKFYDATTCHRL
                     TAYPTLKVLQCGDPSGTGERGPGYKYKDELPTNLPPAPNDPTGERRIYPRGTLAMANAG
                     PDTNGSQFFLVTADSTLRPNYTVFGKIKPEGLRTLDKVAASGIKPTPDNPAPVDGSPAK
                     PVDIKRAKKDC"
     gene            complement(16954..17505)
                     /locus_tag="BN6_RS30910"
                     /old_locus_tag="BN6_64210"
     CDS             complement(16954..17505)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015802178.1"
                     /locus_tag="BN6_RS30910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64210"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_041314641.1"
                     /transl_table=11
                     /translation="MTDLASPDPLDDGVVRVRPWRDTDLSCVEQASRDPRIPQGTTVPA
                     RYTLEAGLAYIARQHARRTSGEGVSMAIAEQHTDQAVGHVNLMLRPQDGVAGIGYWIVP
                     AARRRGIASRAIALTTAWGLNVGGFARVEAWVEPDNHGSRRVLEINGYLLEGRLRSFLT
                     FGTRRADVLVYSRLATDAAR"
     misc_feature    17500..17514
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(17633..18355)
                     /locus_tag="BN6_RS30915"
                     /old_locus_tag="BN6_64220"
     CDS             complement(17633..18355)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN6_RS30915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BN6_64220"
                     /product="hypothetical protein"
                     /protein_id="WP_015103776.1"
                     /transl_table=11
                     /translation="MRWSAVPLLLCVVLAAGCASRTAVPEPTLEPVARDASSLVTSLVA
                     RVEGQYSVRFDAETAMSGRKVRAEGGLVRSRDARLVMLREDNVEVVVLPDAGYLRSDGG
                     SWTRLGRTDRAGVKSGVAVDGLADEVDPRSVVSALRGSLVVETGDESLDGVPTHRYTML
                     VDLRSQAEQTSDVTHRSQLLAAYESGFTATAVLWVGPGGLPVRVEQVLKTLEDNIFQRT
                     QHRFTNWNTDLRIVAPTR"
     misc_feature    18378..18393
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.89"
                     /tool="antismash"
     gene            18454..19104
                     /locus_tag="BN6_RS30920"
                     /old_locus_tag="BN6_64230"
     CDS             18454..19104
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103777.1"
                     /locus_tag="BN6_RS30920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64230"
                     /product="MOSC domain-containing protein"
                     /protein_id="WP_015103777.1"
                     /transl_table=11
                     /translation="MPHVLSVNIGARADFEPAVIGHTGHDKRPVSGAVRISAPAGPGSG
                     LAGDHISDGRSHGGPDQAVYAYSREDLDTWSAELGRDLAPGIFGENLTTVGVDPTNAVV
                     GERWRIGGTLLQVTDPRIPCRTFVGVMDVQGWMKLFTERALCGTYFRVLEPGSVTAGDE
                     IVLVDRPDHDVTVQLVFRALTLEPELLPRLLAVAPHLTEKTRAKVRRRLGAAV"
     gene            complement(19156..19995)
                     /locus_tag="BN6_RS30925"
                     /old_locus_tag="BN6_64240"
     CDS             complement(19156..19995)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103778.1"
                     /locus_tag="BN6_RS30925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64240"
                     /product="aldo/keto reductase"
                     /protein_id="WP_015103778.1"
                     /transl_table=11
                     /translation="MSETFSLGGDLTVNRLGYGAMRLTGEGIWGPPADRDNALAVLRRA
                     VELGIDFIDTADSYGPHVNEELIREALHPYADNLVVATKAGLVRTGPNEWHTLGKPFYL
                     RQALETSLRRLGVERIDLFQLHRIDPEVPLEDQVGELKKLRDEGKIRHIGLSEVDVSQL
                     AAAREVVPIASVQNLYNLANRRHEAVLDYATEHNIAFIPWFPVATGELARPGGVLDTAA
                     KDHGATPAQLALAWLLRRSPVVLPIPGTSSVAHLEENTAARSIELTDEQFEKLSALG"
     misc_feature    19955..19970
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.31"
                     /tool="antismash"
     gene            complement(20135..22162)
                     /gene="paaZ"
                     /locus_tag="BN6_RS30930"
                     /old_locus_tag="BN6_64250"
     CDS             complement(20135..22162)
                     /codon_start=1
                     /gene="paaZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR02278"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103779.1"
                     /locus_tag="BN6_RS30930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_64250"
                     /product="phenylacetic acid degradation bifunctional
                     protein PaaZ"
                     /protein_id="WP_015103779.1"
                     /sec_met_domain="TIGR02278 (E-value: 0.0, bitscore: 1014.8,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Aldedh (E-value: 1.5e-58, bitscore: 197.4,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMLRSYVSGRWHTSSAEGAPLHDAVTGEEITRISSAGVDMAAAL
                     DHGRRTGGPALRELTFHQRGALLKALASYLREHREELYALSARSGATRTDSLIDVDGGI
                     GVLFTYASKAKRELPNDTVYVDGALEPLSRGGTFVGRHIGTPLRGVAVQINAFNFPMWG
                     PLEKFAPAFVAGVPSLIKPASQTAYITEKLVELMLASGLLPEGSVQLVSGSAGDLLDHL
                     TAQDLVGFTGSASTAQLLRTHPAVIRSSVRFNAEADSLNCSILGPDATPGTPEFDLFVK
                     QLVSEMTTKAGQKCTAIRRALVPAELLDDVAEAARARLAEVVIGNPANESVRMGALAGL
                     EQREEVRRSLKTLLEAGEVVYGSPDTVEVVDADAERGAFLSPVLLKADPDRAQPHEVEA
                     FGPVSTLLPYSGAAHAVELAARGAGSLVGSVVSYDTSFVREVVLGVAPWHGRLLVLDRD
                     DAKESTGHGSPLPALVHGGPGRAGGGEEMGGIRGVLHHLQRTAVQGSPRVLTAVTGQWT
                     AGAERTESAEHPFRKSLAELRIGDSVVAGPRTVTLEDVEHFASFTGDTFYAHMDEEAAA
                     ANPFFGGRVAHGYLVVSFAAGLFVSPEPGPVLANYGLDNLRFLTPTFPGDELTVTLTAK
                     QITPREDQDYGEVRWDADLVNQKGESVAKYDVLTLVAKTR"
     CDS             22165..22254
                     /gene="allorf_7166508_7166597"
                     /locus_tag="allorf_7166508_7166597"
                     /protein_id="allorf_7166508_7166597"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVDLLVGAGGCPGLPDSKAPLLSSWLDSS"
     CDS_motif       22165..22194
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVDLLVGAGG"
                     /locus_tag="allorf_7166508_7166597_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       22195..22254
                     /prepeptide="core"
                     /locus_tag="allorf_7166508_7166597_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.90"
                     /molecular_weight="1883.1"
                     /monoisotopic_mass="1882.0"
                     /core_sequence="CPGLPDSKAPLLSSWLDSS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVDLLVGAGG"
                     /leader_location="[22164:22194](+)"
                     /alternative_weights="1901.1"
                     /alternative_weights="1919.1"
                     /alternative_weights="1937.2"
                     /alternative_weights="1955.2"
ORIGIN
        1 cgggtgcgca aggccaagcg cgaggtgcgc gtgcggtgcg acccggaccg gccgcacccg
       61 ttcaccaccg gcgaccaggt gcggctgctc tacccgggca cgccgaaccg cacccgggac
      121 gcggtggtgc tcggcgagtc ggccgaggac atcgtgctgg tggagagcgt cgcgccggac
      181 gacgtggacg gcgaccggcc ggcggcggtg ctgcccggca gcccggtgcg gccctcgccg
      241 aaggacgagg cggtgtacga gctcgcgcgg atggtcgccg agtcgctgcc cgtgctcccg
      301 ccgcaccccg gcgtcgacct ggcgcgccgg gcctcgcccc ggctgcgcgg gctcgcggaa
      361 ctgcccgccg gcggtgacgt gatcgcggac gtcatcgagg cggtcgaccg gctcgacggg
      421 tcggcgctgg ccgtgcaggg gccgcccggg gccgggaaga cctacctcgc cgggcggctc
      481 atcgcgcacc tggtgcgcgg cgggcgcagc gtcggggtga cgtcgaacag ccacaaggcc
      541 gtggagaacg tgctgagcgc ggcgcaggcg gccgggcgcg agctgggcgt gccgatcccg
      601 accgccaaac ggcccaaggg caccccggcg aaggactgca cgtgggagca gccgaaggac
      661 aacccggcgc tggtccggtg gcgcaccgac cagggcgcgg gtcacctggt cggcggcacg
      721 gcgtggacgt tcgccaacgc ggcggtccgc gagcagccgt tcgacgtgct gatcgtggac
      781 gagggcgggc agttcgcgct ggccgacgcg ctggccgtgt cgacgtgcgc gcgcaacctg
      841 gtgctgctcg gcgacccgca gcagctgccg caggtcgtgc agggcacgca cccggcgggc
      901 gcggacgcgt cggcgctcgg ccacctgatc ggtgacgccg acgtgatccc ggcggaactg
      961 gggtacttcc tcgaccagac ccggcggatg caccccgacg tgtgcgaacc ggtgtcgcgg
     1021 ctgtcgtacg cggggctgct gcacgcgcac ccgacgacgg ccgcgcgcgg cgtggacggg
     1081 ctggtgtccg gggtgtacgt gcacgaggtg gagcaccggc acaacaccac cagctccgtc
     1141 gaggaagcgg cggcggtcgt ggagatcgtg aagtcgctga tgggtcgcat gtggacggac
     1201 ggggtgaacg cgcggccgct ggacgactcg gacgtgctgg tcgtggcgcc gtacaacctc
     1261 caggtccggt tggtgcgccg ggaactggaa cgatccgggt acgagcacgt gcgggtcggc
     1321 acggtggacc ggttccaggg gcaggaggcc ccggtggtgg tcaccacgat gacgtcgtcg
     1381 gcggccgtcg acctgccgcg cggactggac ttcttgctgt cccgcaacag ggtgaacgtg
     1441 gcgctgtccc gtgcgcaggg tgtcgcggtg gtggtgtgct caccgcgcct ggtcgaggcg
     1501 gacatccgcg gcgtcgacca gttgagattg gtgtccggga tgatcgggct caccggcgag
     1561 gcgcgcccgt ggcccatcga cggcatctat gcccaaaggc tatgactcca tccggtcaag
     1621 cgctcttact gtgaaaaccg cgagaacctt ccaccctgca ccgaaggaga tcgtgtgacc
     1681 ggcaagttgc tgcgcctcgc cctcggggcg ctgttcacct ccctcgccct cgtgggaacc
     1741 agcctgacca ccgcggcgac ggcggcaccc gccgcgccgt ccgcgctggc caggaccgtc
     1801 tactacagcg cctccgggta ctcggcggaa gccgaccagg ccgcgcagat ctggaactcc
     1861 agggtgccca acctgcggct cgtccgcggc ggcagcgcca ccatccgaat cgccgcgacc
     1921 aacggcggcg gctcccgggc ctacccctgc gggctcgggt gcgccacgat ctacatcgac
     1981 aaccgcgacg ttgccgcggg caactacgcg ctgcggatcg tggcacacga gatcgggcac
     2041 ggcctggggc tgcccgatac gtacaacggc atctgctcgt acctgatgtc gggcggcagt
     2101 gcgggcacgt cctgccgcaa cgtgtacccg aacgcccaag aggcgaaccg ggtgaaccag
     2161 ctcttcgcgg gtcgcgctgt cgcggccgtg ggcaaccccg aggtctacgc gaggggctga
     2221 gctggtcgaa gtgttccggg gtgtggtggc ggaacgcact ccccaccacc acacccgccc
     2281 tgatcgtccg gatccgacgg ccgacgctcg gcggccgggg ccggcggagc cggacgagaa
     2341 gaccagggca ccgtgaacga ccgtgccgga caggcctccc gcctgtccgg caccgtcacg
     2401 tccgccttcc gatactccga cctgccggca ctccgagctt ccggcactcc cggcccaccc
     2461 tcggaccggg tggccgggac ccgcgcgccg gtcggcgcgc ggcaccggac aggtcaggac
     2521 ttcggcaggc cgggcgggtt gacctccgag gcggtgacgg cctcgttctc caggccccag
     2581 cgggccagga cctcgccgta cttgccgttc tcgatcaggt ggtcgagcgc ctccgcgacc
     2641 ggttccacca ggccgctgcc cttcttcgtg gtggccgcga tcttgcccgg gagctcgccg
     2701 ccgccggaga tcgtgccgat cacctcggtc ttgcccgacg tgaccgcgtg gtacgccgac
     2761 accgggttcg ggccgaggta ggcctcgatc cggcccgact ccagcgccag gtagtagtcc
     2821 gacgcgttct ggaagtactt tatgtcggtg ggcttgaggc ccgcggcctc gttcttccgg
     2881 ctccactcca ccaggatctt ctcctggttg gtgcctgagc cgacggcgat cgtccggccc
     2941 gccacgtcct cgggtctggt cacccgccac gagtcgccct tgcgaccctc gaacgccagg
     3001 gtgtccagcc ggtaggtcgc gaagtcgtac ttctccttgc gcgcctcggt caccgtgatg
     3061 ttcgacaggc ccagcgggta cgccccgctg tccaggccga cgaacaggtt ctcccaggag
     3121 gtgacctcca gtcgcggctc caggcccagc acgccggcga tgagcaccgc gatgtcggtc
     3181 tccacgccga tgatcgtctt gtcgtcgctc gcgtagaacc gcagcggcgg cgcggtcgtg
     3241 gacgaaccgc ccaccaccag cttgccggtc tgccggacgg actccgggac cttggcggcg
     3301 atcgcgtcga ccttggtcgc ggtgatccgg tcctgctgcg ggctcaggtt gacggtcttg
     3361 ccgccggcga cgaccttgtc ctcggtcacc gccccgtcgg cacccgcgca cgccgccagc
     3421 gccagggccg ccgccgcgac gattccggtg atcttccctg cggacacggt gtttcctctc
     3481 agagcacttt ggacaggaac gcgcgggtgc gcggttgttg cggatcgtcg agcacctggc
     3541 ccggcggccc ctgttcgacc accacgccgc cgtcgaggaa gacgacggtg tcggcgacct
     3601 cgcgggcgaa gccgacctcg tgggtcacca cgaccatcgt ggtcccgctg cgggccaggt
     3661 ccttgatcac gtcgagcacc tcgccgacca gctccgggtc cagcgcggag gtgggctcgt
     3721 cgaacagcag gaccttcggc tccagcgcca gcgcgcgggc gatggcgacc cgctgctgct
     3781 ggccgccgga caggtgcctg gggtaggcgt cctccttgtc cgccaggccg acccgggcca
     3841 gcagggcgcg cgcccgggtc cggacctcgg cgaccgggcg gcgttgggcg gacaccgggg
     3901 cctcgaccac gttctccagc acggtcaggt gcgggaacag gttgaagttc tggaagacga
     3961 acccgatgtg cgtgcgctgc ttgaggatct cccgctcgcg cagctcgtgc agcttgtcgc
     4021 cgacccggcg gtagccgacc aggtcgccgt cgatgctcac gtggccccgg tccaccttct
     4081 ccaggtggtt gatggtgcgc agcaacgtcg acttgcccga cccggacggc ccgagcacca
     4141 ccacgacctc gcccgcccgg acctccaggt cgacgccgcg cagcacctcg ttggcgccga
     4201 agctcttgtg gatcccacgc aggtccacca tcacctcgcc cacttccaac cccccttgtc
     4261 gcgcgtcgaa cccttggcgt agcgcttctc cacgtagtgc tgaacgaccg acaggagggt
     4321 ggtcagcacg acgtaccaga cggtcgcgac catgagcagc gcgacgaccc gcgcgttgcg
     4381 cccgtacacc acctgcacct ggtagaacaa ctcgccgatg gccaccacgg acacgatcga
     4441 cgtgcccttg aacaggctga tgacctcgtt cgcggcgttc ggcaggatcg accgcatcgc
     4501 ctgcggcagc acgatccggc ggaactggcg ggacttcggg atgcccagcg ccgccgcggc
     4561 ctccagctgg ccgtggtcga ccgagatgat gccggagcgg acgatctccg ccgcgtaggc
     4621 cgcctggtgc aggcccaggc ccagcaccgc cgcgcccatc gggctgatca ggtccttggt
     4681 gtcgacgccg aagaacgtcg ggccgaacgg gatcccgaac tccagttcct ggtagaggta
     4741 ggagatgttg aaccagaaca ggacctgcac gatcagcggg atggaccgga acgcccagat
     4801 gtaggtccag gacacgccgg ccaggaacct gctgtgcgac aaccgcatca gcgcgagcac
     4861 gatgcccagc gcgaacccga tcgcggtgcc gtggagggtc agttccaggg tcacgccgac
     4921 cgcgcgcagg atggactcgg cggtgaagta gcgggcgaag gtcggccagt cccaaccggg
     4981 gttggtgacc aggccgttga cgaactgcgc cagcaggacg aggacgacca cgacgccgac
     5041 ccaccgccac gggtggcggg cgggcacgac cttgagccgg gagaggtcgt cgtcgggggc
     5101 gcgcaggcgt ggttgtgcgg acacgctcat ggtggggtcc ttcgacagag cccgccgagc
     5161 acgacggcac cggagggccg gttaccgcgc ggcgggtgtg gggccagcgg gtgtgggggg
     5221 gcgagcgccg gtcagccgcg gcgacagatc gcgctggaga cccggccgta gtcgacgtgc
     5281 ctgcgggagc agaggacggc cattcgcgct ccccttccag gcttgtgttg acgattcgtt
     5341 gcacggagcc ggtttcacac gactggacga gaagttgcca cttcgcccgc tctcgaacaa
     5401 gagtgcccac ctgctgaaac cactatgtgt cgccggttga caaggccgcg catcactcga
     5461 atcgaccaat gtcgggcgtg aacgggcggt gacaccgggc cgtatgccgg ttgcgcccgc
     5521 catcgcactc gcacctccgc gcgcggaggc atttatgtcg tattccgacg aggattcctc
     5581 ccgctacgac atttctccga ctccgtccac gacccgttct cacgaatccc gccgatggcg
     5641 cacgagcgtg ggacggtcgg atgcgaagca ggggcgttcg ggcgaaccgg ccttccacca
     5701 ccacgcgcgc cgggtcggaa cctctcccgg ccggttcgca tcccgcccac caggagtagc
     5761 aaacgcagcc cgtccggacc gtcgacggca gggtccagaa gctccggtgc tgtgccgtcc
     5821 agccgcgtgg tcccggggtg tcagtgcacg gccaccaagt agatgccgta gccggcgacc
     5881 gcggcgcaca ccaggaagca cgcggccggg acgacgcggt tgccgcgcga tgtggcggcc
     5941 aaccctgcgg agaacagcgc cacggtgccc gcgccgagcg cgaaggagac caggaagacc
     6001 tgtcccaggg cggtccagtc gaggtgcacg gcggttctcc tcacgcggcg tggttgacgt
     6061 tgtgcgcgcc caccggatca cggcgggaca gggtccagca gaccgccgcg accacgacgc
     6121 cggcgaccgc gaccgcgagc acgccgaccg gtccccgcgc ggcggtctcg ccggcgagcg
     6181 ccccgacgag cgcggcggcg ggcagggtga gcagccaggc gacggccatc cggccggcga
     6241 cggtccagcg cacgtcggcc aggcgcttgc cgacgcccgc gccgaccacg ccgccggcgc
     6301 acacgtgcgt ggtggacagc gcgaacccca gttgcgacga cgtcaggatc acggtggccg
     6361 cggcggtctc ggccgcgaag ccctgcggcg gttcgatgtc ggtgatgccc ttgcccaggg
     6421 tgcggatgat ccgccagccg cccagccacg tgccgagcgc gatggccgtg ccggcggaca
     6481 cgatcaccca cagcggcggt tcggctccgg cgggcagcgc gccggccgtg atcagggtga
     6541 gcgtgatgac gcccatcgtc ttctgcgcgt cgttggtgcc gtgcgccagc gacaccagcg
     6601 acgccgacgc gatctggccg taccggaagc cgcgcgtggc ggccttcgcg cggcgggtga
     6661 tccggtaggc gaggaaggtc gcggtgccgg cgacgacggc cgcgatcacc ggcgacgcga
     6721 cggcgggcac caacaccttc tccaccaccg cggcgaaccg caccgcgtcc gcgccggccg
     6781 cgacccacgt cgcgccgatc agcccgccga acagcgcgtg cgacgaactc gacggcaggc
     6841 ccagcagcca ggtcgccagg ttccacacca cggccccgac cagcccgccg aacacgatcg
     6901 ccggcccgat ccgggcctcg tcgaccagcc cgctggagat ggtccgcgcc acctcgatcg
     6961 acaggaacgc ccccaccagg ttcaacaccg ccgacacggc gaccgcgacg cgcggcgaca
     7021 gcgcgccggt cgcgatggac gtggccatcg cgttggcggt gtcgtggaac ccgttggtga
     7081 agtcgaacgc caatgccgtc aacaccacga cgacgacaac cacatccacg ccaacacctc
     7141 cgcacaccga cgacgtccgc ctgggttgcc gggcgcggtg aacgcgccga catgcccggg
     7201 tgaacacccg ccgcccggtc cgggaagtgc gctgcccgcg tccggagggc cggacgcggg
     7261 caggtgggcg aggagggtca gacggtggcc agggccgggt agtcggtgta gccgcgctcg
     7321 tcgccgccgt agaacgtcga ggtgtccggg gtgttgaacg ggccgccgga ggccagccgc
     7381 tcgggcaggt cggggttggc caggaacagc gcgccgaacg cgaccgcgtc ggccgtgccg
     7441 tccgcgacca ggccgagctc ggcgggcccg gtcacgccgc cgggggtgtg cgggttgagg
     7501 atcagcgcgg agcgggagcg ctcgcgcagc tcccgggtcg actcccggtc gctctccagg
     7561 acgtgcaggt aggccaggcc gaccgggtcg atcgcgtcga ccagcgccgg gtacagctcg
     7621 cggtggtcgt gctcggcgat gtcgttgtag gtgttggccg gcgagatgcg caggcccagc
     7681 cggtgcgcgc cgatggcgtc ggcgacggcc tccacgacgg cgaccgcgaa cctggtgcgg
     7741 ccggccaccg aaccgcccca cccgtcggtg cgcaggttgg tgttgggcgc gaggaactgg
     7801 tggatgaggt agccgttcgc gccgtgcagc tcgacgccgt cgaaaccagc ggccacggcg
     7861 ttgcgcgcgg cggcggcgaa gtcggcgacg gtggcctcga tgtcggcgtg gctgagctcg
     7921 accggcgtga cgaagtcggc catcgacgtc ccggtgaaca cctggcccgc cgcgcgcacc
     7981 ggcgacgcgc cgaccgggtg caggtcaccg gccagcaggc tggggtggcc gatccggccg
     8041 gtgtgcatga gctgggcgaa gatccggccg ccggcggcgt gcacggcgtc ggtgacgccc
     8101 cgccacgcct cgacctgccc ggcggagtgc aggccggggg tgtccgggta gccctggccg
     8161 accggggagg gctggatgcc ctcggtgatg atcagcccgg cggacgcgcg ctgggcgtag
     8221 tactcggccg tggcctgcgt cggcgtcgtg ccgtacgcgc ggctgcgggt catcggggcc
     8281 atcacgacgc ggttgggcag gcgggtgccc gcgaggtcca gcgggtcgaa ggcggtggtc
     8341 atctctgggt cctccggcaa gtggcgacga gtgcctgtcg gacgatcacc cggcaggcac
     8401 atgcctgtcc gaacaggcat ttacctgttc gaacaggtat cacccgatgg atgttcccgt
     8461 cgtgatcacg atcactcctg gtacggccgt acaattagag tcatggctgg tcaggcagcg
     8521 aaaccgacga gtgtccccgt tccgtcgacc gcggtgtacg ggccgatcag ccatgccatc
     8581 ttccggatcg cccgcctgca ccggatgctc gcgggccagc tgctgcgcga ggccggcctg
     8641 caccccggcc aggagctggt gatgatgcac ctgtgggaca gcgggccgcg ccggcaggcc
     8701 gagctggtcg acgtgctgga ctccgactcg gccaccatga cccgcaccgt gcagcggctg
     8761 gaacgggccg ggttcgtccg ccgcaccccc gacccgaccg accggcgggc caccctcgtc
     8821 gaggcgaccg ccgcgagcca ggcgctgcgc caccaggtct gccggatctg gcaggagctg
     8881 gaggaggcca ccacggcggg ctgcccggac gtcaagcgcg gcgagttcct gcgcacgctg
     8941 gagcagctgg agtgcaacct ggtcacccgg accggccgct ccccgctgcc gcagagcgcc
     9001 gccacgaccg gcagcggcag ggccgccgga cattcgaccg tgaccgacac caggtagccc
     9061 accgcggccg acttttcgcc cggttgtcat gccgctgacc cctatcgggt gaacgtgagg
     9121 tagaacatgc cggtgcaacg gtgggtgttc gcggtgctgg cgctggcgct ggcgacggcg
     9181 gggtgttcga cgccggtcgc gggcaagccg gtcgccggtc cggtcacggt ggagggcgcg
     9241 gcccccgagg tcgtgcggtg gatgaacaac ttctgcggcg tcgccaacta catggtcgcc
     9301 tccggcgggg tcaagttcga ccagccgccc gccgacccgg tcgccgccaa gaaggcgatc
     9361 agcgacgccc tgggccgcgt ggtcgacgtg ctcaacgtcg ccgtgcacga cctcgaggag
     9421 ctgacccccg ccccggtgac ggccgcggac gccgccgtcg aggtgatcgt cgagccgctg
     9481 tccaaggcac gggacaagtt cgtctccgcc aagtccaccg tggacggcgc ggcggagctg
     9541 accaccgacg tgttctcggc cgtgatgcag aacatgaccg aagcggtgtc ggtgatgaac
     9601 gaggccgtgg agaagatgtc cgtggtcaag ctccccgaca ccttcaccac tgccgccgag
     9661 caggccgaga actgcaagaa gtagggctca gagccggccc cggcggactg cccgcgcgtc
     9721 tgcctggaac ctggtccgcg cgcccgcccg gtccatcaga gccgacttga acggcagggt
     9781 cggcgtcacc ggggcccgct cccccaccgc ctccgattcg gcggtcccct ccagccggcc
     9841 gggaaccgtc acgcccgccc cggagcaccg tcacgcccgc ccctgggcac cggcgcgtcc
     9901 acccccggcc acctgcggtt tccgcaacac ggcggagtgc cggcaaatct gggggcacac
     9961 cccccatgtg cgggatcccg tcgcgtgaca cttttgcaac gtgatcccgt ccgccgtaga
    10021 ccggctcccc gcctcctggt ggcaccgcgg cgtgcgcggc gggtcccacg aactggtcgc
    10081 cccacgaggg cggccggcat gggccgcgtt cgtggaacgc gccaccgcga ccgcggccca
    10141 tgcaacattc cccggcggcg actgggacga ggcgttcgcg ttcgcgctgc gccccctggt
    10201 cgacgccgcg cgggcgcagg acgcccggct ggacgacgac ttcggccgcc ggctcggcct
    10261 gcgcctggcc cgcctggcgg cccgcgcgct ggtgctggag ctcaacctgg agcggctggc
    10321 gcaccggctg gtgggcgaga ccccgcagga gcggttcgcg cacttcgtgc agcacctcga
    10381 cctggccgac ctggtcgcca agtacccggt gctggcccgg ctgctcggcc aggcgtgcct
    10441 gcacgccgtg gccgcgcacc gcgaactgct ggaccggttc gccgccgacc gcggcacgat
    10501 cgtgcgcacc ctgctggacg gccgcgaccc gggtcgggtg gcgcaggtcg agaccggtcg
    10561 gggcgacgcg caccagcacg gccggtcggt ggccgtgctg accttcgagg acggccgccg
    10621 ggtggtctac aagccgcggc cggtggcgct gcacgcccgg ttcggcgagc tggtggcgtg
    10681 gttcgacggg cacaccaggc tggggctgcg ggtgccgcgc gcggtcgccc gggagacgca
    10741 cggctggctg gagttcgtgg accaggcgcc gtgcgcggac gtgaccgagg tgggccgctt
    10801 ctaccaccgg ctgggcgcgc tgatcgccct gctgtacgcg gtggacggca ccgacatgca
    10861 ctacgagaac ctgatcgcgg cgggcgacca gccggtgctg gtggacgtcg agacgctgtt
    10921 ccacccgacg gtcggcatcc cggccgaccc ggcggtgcgg gcgctggccc ggtcggtgca
    10981 ccggaccgcg gtgctgcccc gggtgctgct cggcgagcac ggcgcgctgg acatcggcgg
    11041 catgggcggc gaccacggcg agctgttccc cgccgacggg gtggcctggc tcaaccccgg
    11101 caccgaccgg atgcggctgg tccgcaggcc ggcgccgatg ccgccggcgc gcaaccggcc
    11161 gtcggtggcg ggcgtggagg cggagcccgc cgactaccag ggcgcgctgc tggccgggtt
    11221 ccgcaccggc tacgacgccc tgttcgacca ccgcgccgaa ctgctcggcg acgacggcct
    11281 gctggccggg ttcgccgacc tgccggtgcg gttcgtgccc cggatgaccc agctctacgc
    11341 gaccctgctg gacgagtcga cgcacccgga cgcgctgcgc ggcgcgccgg accgcgacct
    11401 cgcgctggac gtgctgtggg acgagtcggc cgaggacgcg ctgcgcgccc tggtgccgca
    11461 cgagctgacc gacctgtggg cgggcgacgt gccgctgttc accacccggc cgggcagccg
    11521 ggacgtgtgg tcggcgggcg gcgagcggct gccggacctg ctgccggagt ccgggctgga
    11581 agcggtggcg cgcaaggtcg ccgcgctgga cgaggtggac cggcacgacc agcagtggct
    11641 gatcagcgcc gcgctggcga gccggccccg gcctgtggac caccgctcgg gcgcgggcgt
    11701 cccggccccg ctggaggcgg gcatccccga cccgcagcgg ctgctggtgg ccgcgtgcgg
    11761 gatcgccgac gaggtgctgg cgcgggccag caccgacggc gggcgggtca actgggtggg
    11821 cctggaactg gtggacgacc ggcactgggc ggtcgccgcg atgggcgcgg gcctgtccaa
    11881 cggctacccc ggggtggcgt tgttcctggc gcagctgggc gcgctgaccg gggccgggcg
    11941 ctacaccgcg ttcgcccggg aggcgatcgc gccggtgccg gggctgctgc ggtcgttcgc
    12001 ggcggacacc gagctcgcgg tggcggtggg cagcggcgcg ttccacggcc tgggcgggat
    12061 ctgctacgcg ctggcccggc tgtcgaccct gctccaggac gacgagatca ccggctggct
    12121 ggccgaggcc gtcgcggtgg ccgagcaggt cgaggcggtc ggcgaggacc cggcgaacat
    12181 cgtggagggc tgggcgggcg ggctggccgc gatgctggcc gtgcacgccg agaccgggct
    12241 gcccgcggcc gaacggctgg cccggcgcta cgccgcccgg ctgatcgcgg ccaaccccgg
    12301 cggcgacggc ttcgcgcgcg gccgggcggg cgtcggctgg gccatgctgc gctacgcccg
    12361 gcacgcccgc gaccagcgcc acggcgtggc cggtcgggcg aacctgcgcg cggatcacgc
    12421 gctgcggcaa cgactcctgg acgtcggcga ggccgaccac agctggtgct ctggcctgtc
    12481 cggcgcggtg ctcgcgcacg ccgcgcaccc cgaccagccg gtcgacacct acacgctgca
    12541 cctcgaccgc tgcctcaacg cgctggcggt gcacgagccg ttgcgcgacc tcagcctgtg
    12601 ccacggcgag ctgggggtgc ttgaatcgct ggcggtgctg gccgaacgcg ggcacgatct
    12661 ggccacggcc atgctgaccc ggcgcgccgg actcgtcctc ggcgcgatcg accagtacgg
    12721 ggcgcggtgc gcgacgccgg gcggtgtgcc gtcggccggt ctgctcaccg gtctgtccgg
    12781 gatcgggtac ggactgctcc gcctcggctt ccccgagcgg gcgccgtccg tgctcctgct
    12841 cgaaacccct gccaatccct accctcgcaa ggagaacccc cgatgagcaa cgccaaccac
    12901 gacgaggtca cgacctggga cgacggccag gacggcgacc accccgccgg ggagatggcg
    12961 ctgtcccgca agtccaagac cggcgcccgc gcccgcgcgc tggcgggtct caccctggcg
    13021 gtcggcgcgt acgtcgtcgt cgccgccggc ctggccgaca gcacgtcggt gagcgcgccg
    13081 gtcacctact gacctcccgc cgggaccacc ccggccggag cgggtcgaca cccgccggac
    13141 tgcccgccca cactgggggt gcgggcagtc cggcgcgggc ttgactaagg tcgggccatg
    13201 cagacccgcg cgccggtcgt ggtcggccgc gacgacgaac tccgggtgtt ggcccggacg
    13261 ctgaccgacg ccgccgcctg tcgcgggcgc gccgtcttcc tggtcggcga ggccgggatc
    13321 ggcaagacca ggctggcccg ggtggccgcg ggcgcggcgt tcgaccgcgg gatgcgggtg
    13381 ctgcgcggtc gcggctcgac catcgggccg atggtgccgt tccgcccgct ggccgaggcg
    13441 ctgatgtcgt tgctgcgcgg cggtgacgcg ccggacctgc gcgaactggg cccgtaccag
    13501 ccggtgctgg gccggctggt gcccgagtgg ggcggcgagc cgcaggcggg ccactccatc
    13561 gtcgtgctcg ccgaggcggt gctgcggctg ctggccgtcg tcggccgggt ccggccgtgc
    13621 ctgctggtgc tggaggacct gcacgactcg gacgccgaga cgctcgcggt catcgactac
    13681 ctggtggaca acctcgacca ggtgccggcc gcgctgctgg tcaccgcgcg cgccgacccc
    13741 ggtccgacgc tggacgtggt gcggctggcc gcgcagcgcg acgccgggtc gctgctggag
    13801 ctgcgcccgt tgcgcgaggg cgaggtgcgc cggatggtgg cgtcctgcct ggaggtggac
    13861 gaggccgagg tgcccgaggc ggtggcccag cggctgtggt cggacagcgc gggcaacccg
    13921 ttcgtcgtcg aggagatgct gcacggcctg gtcagcggcg gcctgctggt gcgcgggccg
    13981 gccggctggc aggtgctggg cgagctgcgg atcaacgtgc cgacggcgct ggtccgctcg
    14041 atcgcgcacc gcaccgaccg gctggggccg cagggccgcg agctgctgtc ggtggcggcg
    14101 gtgctgggcc accggttccc gctgtcggtg ctgcgcgcgg tgaccggcat ggacgaccac
    14161 agcctgctca cccacctgca cgcgggcgtg gcggcgcagc tggtgacgcc ggacgagccg
    14221 gtgcccgact ggtacgcctt ccggcacccg ctgaccgccg aggcgctgct cgcgcagctc
    14281 accccgacgc accgggcgga cgtctcgcgg cgcaccgcgg acgcggtcgt ggagctgcac
    14341 cccgggctgc ccggcgagtg gtgcccgctg gtggcctcgc tgcggctgga cgcgggccag
    14401 aacgccgagg cgggcgcgct gctggccgag gccggccggc gggcgctggc cgacggcgcg
    14461 gcgggctccg cggtgcggct gctcgaccac gcgcaccggc tgccgctggg ccgggtcgac
    14521 gtggggctgc gcgcggacgt gctggcgtcg ctgctgccgg cgctgggcga ggcgggccag
    14581 ttcgagcggg cgttcgcgct gcaggacgcg gtggccgagc tgagcgcggc cggtctggac
    14641 cgggtgcgcc gcgccgagct gcacaccggg ctggcgaagg tggcctggct ggccggccgc
    14701 gaagaggacg gcatggcgca ggtggaggcc gcgcggtcgc tgctcggccc ggacgccgac
    14761 gacgcgcact cggcccggct cgactcggtg gaaaagttcc tgaccctcga cgcgcggctg
    14821 ccggaccgga tcgctaagcg gagctgctgg cccgccgggc ggccgaggcg gcccgccggg
    14881 cggcgctgcc cgaggtgggc tgcgaggcgt ggcagctgct cggcatcctg gcccgggaac
    14941 gggacctggg cgaggccacc gaccacttca cccgggcccg ccggctcgcc gaggagcacc
    15001 ggctgccgat ccagcggatc tacgccgtgg tgcggctggc cgggctggac tggctggccg
    15061 acggctcggc ggcggagctg gtcgaggcgc gcgaggaggc gctgcgggtc ggcgcgatca
    15121 cggtggccta caacgtcgac gcgatcctcg ggctggacct cgtgctgcgc gggcagtacc
    15181 aggcggcgcg cgagcagctg gcccgctgcg gcgaggggac ccgccggctg caactcaagt
    15241 cgatgacgct ctacgtgctg atggcccagg ccaccgccgc cgcgcaccag ggccgtcggt
    15301 ccgaagtgga cagtgcgctg gcggagttca ccgcgctggg cggggtcggc tcgcaggagc
    15361 ggccgctgtg cttcggcctg gcgcgggcgt tctgcgcgct gatggaggag gaccgcgacc
    15421 tcgccgccca cgacgtggcg cgggcgatgg cctacgaggc ggagacgccg accacgttcc
    15481 acctgtccgg cacgcacggc ctgcggctgc tgctgggcgc gctgtccggc gcgctggacc
    15541 acgcggcgta ccgggagatc acccgttcgg cggcggccgg gatgcggtgg aaccgggtgt
    15601 tcgggcagtt cgcgctggcc gtgctgcacg gccgggaggg ccgggaggcc gaggccgccg
    15661 cggcggtgcg ggcggcccgg gacgcggcgt cgatctaccc gctggcccgc cacctcgggc
    15721 tgcgcctggt cgccgaggcg gcggtggccg acggctgggg cgagccggtg gcctggctgc
    15781 gcggcgcgga ggagtacttc caccaggccg gcgcgacggc cgtggccagc gcgtgccggg
    15841 gcctgctgcg ccaggtgggc gcgtcggtgc cgcagcgccg gacggggtcc gaccaggtgc
    15901 cccgggagct gcgggcgctg ggcgtgaccg tgcgggagtt cgaagtgttc cggctgatgg
    15961 cgggcaggct gggcaacaag gcgatcgcga cccggctgca catctcgccg cgcacggtgg
    16021 agaaacacgt ggccagcctg atcaccaaga ccgcgcagcc ggaccgggag tcgctcagcg
    16081 cgttcgccgc cgacctggga ccctccgacc ggccctagcc ggggcgcggg gcggggcgct
    16141 aggaactgca ccgtgaggat cctcttggca ctggtgctga tggtggtcat gggcggtgtc
    16201 gtcggcgtcg gcggcgtggc ccaggcgtcc gaagagccgt accgcgaccc cgacgtgacg
    16261 cggggtccgt gcgcgtacac caagaccccg gacgacccgg cggcgcggcc ggtgaagctc
    16321 ccgccggacc cgaggcgcac gccggaccgg ggccgggtcg aggtgctgct caagaccaac
    16381 cagggcgaca tccccctggt gctcgaccgc gcgcaggccc cgtgcaccgt ccagagcttc
    16441 ctgcacctgg tggagaagaa gttctacgac gcgaccacgt gccaccggct gaccgcgtac
    16501 ccgacgctca aggtgctgca gtgcggcgac ccgagcggga ccggcgagcg cggccccggc
    16561 tacaagtaca aggacgagct gccgacgaac ctgccgcccg cgccgaacga cccgaccggc
    16621 gagcggcgga tctacccgcg cggcacgctg gcgatggcca acgcgggccc ggacaccaac
    16681 ggcagccagt tcttcctggt gaccgcggac agcacgctgc ggccgaacta cacggtcttc
    16741 ggcaagatca agccggaggg cctgcgcacc ctggacaagg tcgccgcgtc gggcatcaag
    16801 cccaccccgg acaacccggc cccggtcgac ggcagcccgg ccaagccggt ggacatcaag
    16861 cgcgccaaga aggactgctg acctgtcacc ggggcaccgc ggcggtgcgg tgccccggtg
    16921 acgggttcga gcgatggccg cgagtggacg tgctcagcgc gccgcgtccg tggcgaggcg
    16981 ggagtagacg agcacgtcgg cgcggcgggt gccgaaggtg aggaagctgc gcagcctccc
    17041 ctccagcagg tagccgttga tctccagcac tcgtcgcgac ccgtggttgt ccggctccac
    17101 ccacgcctcg acgcgcgcga agccgccgac gttcaggccc caggcggtcg tcagcgcgat
    17161 cgcgcgggag gcgatccccc ggcggcgggc ggcggggacg atccagtagc cgatcccggc
    17221 gacgccgtcc tgcgggcgca gcatcaggtt gacgtgcccc accgcctggt cggtgtgctg
    17281 ctcggcgatc gccatcgaca cgccttcccc cgacgtgcgc cgcgcgtgct gacgggcgat
    17341 gtaggccagg cccgcctcga gggtgtagcg cgcgggaacg gtggtgccct gcgggattcg
    17401 ggggtcccgg gatgcctgct cgacgcacga caggtccgtg tcgcgccacg ggcgcacgcg
    17461 gacgacgcca tcgtcgagcg ggtccggaga agccagatcg gtcacggtcg gccatttcag
    17521 cacaacgcag cgcaagcgtc atccggattg gacggttctc ggcttgatcg accggggtgg
    17581 acgacgggct cagctcccgc gcgaggtgtc gccgcgcccg agccgacctc ggtcaccgcg
    17641 tcggtgcgac gatcctgagg tcggtgttcc agttggtgaa ccggtgctgg gtacgctgga
    17701 agatgttgtc ctccaacgtc ttgagcacct gctccacccg caccggcagg ccgccgggcc
    17761 cgacccagag cacggccgtc gcggtgaagc cggactcgta ggccgccagc agctgggacc
    17821 ggtgggtcac gtcggaggtc tgctcggcct gcgaccgcag gtcgaccagc atggtgtagc
    17881 ggtgggtcgg cacgccgtcg agcgactcgt ccccggtctc cacgaccagc gagccgcgca
    17941 gcgccgagac caccgagcgc gggtccacct cgtcggcgag gccgtccacg gccaccccgg
    18001 acttcacgcc ggcgcggtcg gtgcgcccga gcctcgtcca cgagccgccg tcggagcgca
    18061 ggtagccggc gtcggggagc accacgacct ccacgttgtc ctcacgcagc atgaccagcc
    18121 gggcgtcccg ggaccggacc aggccgccct cggcgcgcac cttgcggccg gacatcgcgg
    18181 tctcggcgtc gaaccgcacc gagtactggc cctccaccct ggccaccagc gacgtgacca
    18241 gcgacgaggc gtcgcgcgcc acgggctcca gggtcggttc cggcaccgct gtccggctcg
    18301 cgcaccccgc cgccagcacg acgcacagca gcaacgggac cgcggaccag cgcatgattt
    18361 cccccacgaa acggatcaac ggcaaccatc ttcgcgcacc cgcgcgacat aaggagtgcg
    18421 aacccgcaaa ctacctgggc taccgttcgg cgtatgcccc acgtgctttc ggtgaacatc
    18481 ggcgcgcgcg ccgacttcga gcccgcggtg atcggccaca ccggtcacga caagcggccg
    18541 gtgtccggcg cggtccggat cagcgccccg gccggccccg ggagcggcct ggccggcgac
    18601 cacatctccg acgggcgcag ccacggcgga ccggaccagg cggtgtacgc ctactcccgc
    18661 gaggacctcg acacctggtc cgcggaactc ggccgcgacc tcgcaccggg catcttcggc
    18721 gagaacctga ccacggtggg cgtcgacccg accaacgccg tggtgggcga gcgctggcgg
    18781 atcggcggca cgctgctcca ggtgaccgac ccgcgcatcc cgtgccgcac cttcgtgggc
    18841 gtgatggacg tacagggctg gatgaagctg ttcaccgaac gcgcgctgtg cggcacgtac
    18901 ttccgggtgc tggagccggg ttcggtgacg gccggtgacg agatcgtgct ggtcgaccgg
    18961 ccggaccacg acgtgacggt ccagctcgtg ttccgggcgc tgaccctgga gccggagctg
    19021 ctcccccggt tgctcgcggt cgccccgcac ctgaccgaga agacccgggc gaaggtgcgc
    19081 cgccggctgg gcgccgcggt ctgacgaccg cgcggcggcg gacccggggc gtcccgggtc
    19141 cgccgcggcg ggggctcagc cgagcgcgga cagcttctcg aactgctcgt cggtcagctc
    19201 gatcgagcgg gccgcggtgt tctcctccag gtgcgcgacc gacgacgtgc ccgggatcgg
    19261 cagcacgacc ggcgagcggc gcagcagcca ggccagcgcg agctgcgcgg gcgtggcgcc
    19321 gtggtccttg gcggcggtgt ccagcacgcc gccggggcgg gccagttcgc cggtggcgac
    19381 cgggaaccac gggatgaacg cgatgttgtg ctcggtcgcg tagtcgagca ccgcctcgtg
    19441 ccgccggttg gccaggttgt acaggttctg cacgctggcg atcggcacga cctcccgggc
    19501 cgccgcgagc tgcgagacgt ccacttcgga cagtccgatg tgccggatct tgccctcgtc
    19561 gcggagcttc ttgagctcgc cgacctggtc ctccagcggc acctcggggt cgatccggtg
    19621 cagctggaac aggtcgatcc gctcgacgcc gagccggcgc aggctggtct ccagcgcctg
    19681 ccgcaggtag aacggcttgc ccagcgtgtg ccactcgttg gggccggtgc ggaccaggcc
    19741 cgccttggtc gcgacgacca ggttgtcggc gtaggggtgc agcgcctccc ggatgagctc
    19801 ctcgttgacg tgcggcccgt acgagtcggc cgtgtcgatg aagtcgatcc cgagttcgac
    19861 ggcccgccgc agcacggcga gcgcgttgtc ccggtcggcc ggcgggcccc agatgccctc
    19921 gccggtcagc cgcatcgcgc cgtagccgag ccggttgacc gtcaggtccc cgcccagcga
    19981 aaaggtctcg gacacctctg gtgctcctct gtcaggttga cggacgtccc caccgcgcca
    20041 actccgcgcg ggccccgtgt tgttcccgat cccgggaccg ggttcggccg gtcccggcag
    20101 ccgggaccgg cggcaggtgc cggggaggcc ggggtcagcg ggtcttggcg accagggtca
    20161 gcacgtcgta cttggcgacc gattcgccct tctggttgac caggtccgcg tcccagcgca
    20221 cctcgccgta gtcctggtcc tcgcgcgggg tgatctgctt ggcggtgagc gtcacggtga
    20281 gctcgtcgcc ggggaacgtg ggggtgagga agcgcaggtt gtccagcccg tagttggcca
    20341 gcaccgggcc cggctcgggc gagacgaaca ggccggcggc gaacgacacc accaggtagc
    20401 cgtgcgcgac ccgaccgccg aagaacgggt tggcggcggc ggcttcctcg tccatgtgcg
    20461 cgtagaacgt gtcgccggtg aacgacgcga agtgctcgac gtcctccagc gtcacggtgc
    20521 gcggcccggc caccaccgag tcgccgatcc tcagctccgc caacgacttg cggaacgggt
    20581 gctcggcgga ctcggtgcgc tcggccccgg ccgtccactg gccggtgacg gcggtgagca
    20641 cccgcgggct gccctgcacg gcggtgcgct ggaggtggtg caacacgccc cggatgccgc
    20701 ccatctcctc gccgccgccc gcccggccgg gcccgccgtg caccagggcc ggcagcggcg
    20761 agccgtgacc ggtggactcc ttggcgtcgt cgcggtcgag caccagcagc cggccgtgcc
    20821 agggggccac gccgagcacg acctcgcgga cgaacgacgt gtcgtagctc accaccgagc
    20881 cgaccaggct gcccgcaccc cgggcggcca gttccacggc gtgggcggcc ccggagtagg
    20941 gcagcagcgt ggagaccggg ccgaacgcct cgacctcgtg cggctgggcg cggtccgggt
    21001 cggccttgag cagcaccggc gagaggaacg cgccgcgctc ggcgtcggcg tcgaccacct
    21061 cgacggtgtc cggcgacccg tagaccacct cgcccgcctc cagcagcgtc ttgagcgagc
    21121 ggcgcacctc ttcgcgttgc tccagcccgg ccagcgcgcc catccgcacc gactcgttgg
    21181 ccgggttgcc gatcacgacc tcggccagcc gggctcgggc ggcctcggcg acgtcgtcga
    21241 gcagctcggc gggcaccagc gcgcgccgga tcgcggtgca cttctggccg gccttggtgg
    21301 tcatctcgct gaccagctgc ttgacgaaca ggtcgaactc gggcgtgccg ggcgtcgcgt
    21361 cggggcccag gatggagcag ttcagcgagt cggcctcggc gttgaaccgc accgacgagc
    21421 ggatcaccgc cgggtgggtg cgcagcagct gcgcggtgga ggccgagccg gtgaagccga
    21481 ccaggtcctg cgcggtgagg tggtcgagca ggtcgcccgc gctgcccgag acgagctgca
    21541 ccgagccctc cgggagcagg ccggaggcga gcatcagctc gaccagcttc tcggtgatgt
    21601 acgcggtctg cgaggcgggc ttgatcagcg acgggacgcc ggcgacgaac gcgggcgcga
    21661 acttctccaa cgggccccac atcgggaagt tgaaggcgtt gatctgcacc gcgaccccgc
    21721 gcagcggcgt gccgatgtgc cggcccacga acgtgccgcc gcggctgagc ggctccagag
    21781 cgccgtcgac gtagacggtg tcgttgggca gctcgcgctt ggccttgctc gcgtaggtga
    21841 acagcacgcc gatgccgccg tcgacgtcga tcagcgagtc ggtcctggtc gccccggagc
    21901 gggccgacag cgcatacagc tcctcgcggt gttcccgcag gtaggaggcc agggccttga
    21961 gcagcgcgcc gcgctggtgg aaggtcagct cgcgcagcgc gggcccgccg gtgcgccggc
    22021 cgtggtccag cgccgcggcc atgtcgacgc ccgccgacga gatgcgggtg atctcctcgc
    22081 cggtcaccgc gtcgtgcagc ggcgcgccct cggcggacga cgtgtgccag cgaccggaga
    22141 cgtagctgcg cagcatggcc atcggtggtc gacctccttg tcggtgccgg tgggtgtccc
    22201 ggcttaccgg acagtaaagc cccactactt tcatcgtggc ttgattcaag ctgatggagc
    22261 aacctcgggc gcgccgccgc ccgagtgacg ggagtaccgc cgaggacacg ggttctggta
    22321 gaagcgacag ccgatcaccg gcatcggcgg cgtcgccggc ggaagtgggc cgttgcggca
    22381 tgattcgccc atgcacgagc tgatcaggtc cgaggccgcc gccgccgagc agcgccgcgc
    22441 gctcaccgaa cccgtcgtgg cggcgctggt gtcgtcgggc accacccggt cgctcgcgcc
    22501 cgcccggctc ggcggccggg agctggacct gccgtcctgg ctggtcgaga tcgaggcgct
    22561 ggccagggcg gacggctcga ccggctggac cgcgatgacc accggcgcca cctcggcgct
    22621 gtcctggtac ctgaccgacg acggcgccga agaggtgttc ggctccccca cgtcggtgat
    22681 cgccgggacg gccgcgccgg cgggcacggc ggtcgcggcc gacggcgggt accgggtgac
    22741 cggccggtgg ggctggggca gcgccgtgcc gctgtgcgac tgggtggcgg gcggcgcgcg
    22801 caccgacggc ggggccacgt tcgcgatctt ccggcgcgcc gacgtgaccg tgcacgacac
    22861 gtggcacgcc gccggtctgc gcgcca
//
